Intracranial pressure probe

Abstract

The present invention discloses an intracranial pressure probe, comprising a shell, one end of which is connected to a hemispherical head, the other end of which is provided with an open nozzle, the open nozzle is fixedly connected to a hollow catheter, a window is provided on the top of the shell, a pressure chip is provided inside the shell, the pressure chip is located below the window, the pressure chip is fixedly connected and sealed to the window by glue, the pressure chip is connected to a wire, and the wire passes through the hollow catheter. The intracranial pressure probe of the present invention uses the wire of the chip itself to bend into a Π-shaped structure to form a chip stop bracket, the chip wire is directly hot-pressed and welded to the chip, the packaging structure is simplified, and the problem of the bending and pulling of the outer catheter of the intracranial pressure probe during use affecting the measurement accuracy is effectively solved; the intracranial pressure probe has a simple structure and a small size, can monitor intracranial pressure and temperature at the same time, has high accuracy and good stability.

Description

Technical Field

[0001] The invention relates to the technical field of intracranial pressure and intracranial temperature monitoring, and in particular to an intracranial pressure probe. Background Art

[0002] The intracranial pressure probe is used to monitor the pressure and temperature of patients with craniocerebral injury during and after craniocerebral surgery. Due to the environmental restrictions of its use, the intracranial pressure probe is usually required to have a small size (generally less than 1.3 mm in diameter), and cannot be pulled out of the skull for zero calibration during use, and the measurement accuracy is required to be extremely high. At present, the intracranial pressure probe generally uses a differential pressure piezoelectric chip to be inserted into the skull to measure the intracranial pressure. Therefore, the metal shell is sealed and packaged, the chip is exposed through a window for measurement, the outer layer of the chip is coated with a biocompatible material, and the chip connection wire is connected to the external signal processing equipment through a pipeline and the inside is connected to the atmosphere. These methods are all well-known technologies. Since the piezoelectric chip itself has the characteristic that the output value changes with temperature and time drift, and since the probe structure is small (generally less than 1.3 mm in diameter), the packaging structure will have a great impact on the measurement results. The measurement error of the intracranial pressure probe caused by the change of the chip output value with temperature and time drift can be corrected in real time in vitro by software and hardware, but the random error caused by the packaging structure cannot be eliminated. Therefore, the packaging structure of the intracranial pressure probe has a decisive influence on the detection accuracy of the intracranial pressure probe.

[0003] At present, the packaging structure of intracranial pressure probes (such as the structure given in the sensor for intracranial pressure monitoring in Chinese patent CN 206197935 U) generally has the following technical defects: 1. The chip wire is directly connected to the chip, and the connection is only fixed by silicone and the tube shell. There is no isolation measure between the connection wire and the chip. During use, the external wiring tube will bend and pull, and the chip will inevitably be disturbed by external forces and generate stress, which will have unpredictable and uneliminable effects on the detection data and detection accuracy of the chip. In severe cases, the intracranial pressure probe will fail; 2. Generally, the structure of the intracranial pressure probe is small, for the convenience of assembly. Many of them are equipped with a support structure integrated with the shell or a separate support. When encapsulating, the chip is directly placed on the support structure or support, but the shell and the chip are not made of the same material. When the external temperature changes (after zeroing at room temperature, they are placed in the skull for measurement), due to the different thermal expansion coefficients of different materials, the thermal deformation of each component is inconsistent, especially the vertical direction of the chip (the direction of the measurement sensing surface of the chip). The stress caused by the deformation will be directly reflected on the chip, resulting in reduced measurement accuracy. Since the intracranial pressure probe is not allowed to be pulled out and zeroed again after being placed in the skull, the measurement error caused by this cannot be eliminated, and in severe cases, the intracranial pressure measurement will fail; 3. Due to the tiny structure of the intracranial pressure probe, the space inside the shell is even smaller, and the gap between the chip and its components and the inner wall of the metal shell is extremely small. During use, static electricity generated by dry environment and other reasons will be introduced into the probe through the patient. Due to the small gap, the discharge of static electricity can cause the measured value to be instantly distorted. When the static voltage is high, it can also affect the measurement zero point of the probe in severe cases, and the zero point cannot be reset, resulting in probe failure. In addition, the patient's bioelectricity will also affect the measurement accuracy, resulting in measurement errors, and these errors cannot be eliminated. Summary of the invention

[0004] In view of the above technical problems in the related art, the present invention proposes an intracranial pressure probe for monitoring intracranial pressure and temperature. The packaging structure and manufacturing method of the probe can overcome the above deficiencies of the prior art.

[0005] To achieve the above technical objectives, the technical solution of the present invention is implemented as follows:

[0006] An intracranial pressure probe comprises a shell, one end of which is connected to a hemispherical head, the other end of which is provided with an open pipe mouth, the open pipe mouth is fixedly connected to a hollow catheter, a window is provided on the top of the shell, a pressure chip is provided inside the shell, the pressure chip is located below the window, the pressure chip is fixedly connected and sealed to the window through glue 1, the pressure chip is connected to a wire, the wire passes through the hollow catheter, a groove is provided on the inner wall of the shell below the window, and the wire is fixedly connected to the rear edge of the groove through glue 2.

[0007] Furthermore, a temperature measuring element is provided below the pressure chip, the temperature measuring element is connected to a wire, and the wire is fixedly connected to the rear edge of the groove by glue 2.

[0008] Furthermore, the pressure chip is hot-pressed and welded to one end of the wire through a chip pad, and the wire connected to the pressure chip is in a Π shape. The pressure chip, the temperature measuring element, the wire and the inner wall of the shell are not in contact.

[0009] Furthermore, the temperature measuring element is a thermistor or a temperature measuring chip.

[0010] Furthermore, an insulating layer is provided on the inner wall of the shell.

[0011] Furthermore, a coating is provided on the top of the pressure chip, and the coating is seamlessly connected to the glue.

[0012] Furthermore, the wire passes through the hollow conduit and is connected to an external circuit.

[0013] Furthermore, the hollow conduit is connected to the open pipe opening by epoxy resin glue.

[0014] The beneficial effects of the present invention are as follows: the intracranial pressure probe of the present invention utilizes the chip's own wires to be bent into a Π-shaped structure to form a chip stop bracket, the chip wires are directly hot-pressed and welded to the chip, the packaging structure is simplified, and the problem of the bending and pulling of the external catheter of the intracranial pressure probe affecting the measurement accuracy during use is effectively solved; the suspension structure of the chip stop bracket is utilized to effectively avoid the measurement error caused by thermal expansion deformation caused by ambient temperature; the insulating layer provided on the inner wall of the shell is utilized to well solve the measurement error caused by static electricity and human bioelectricity; the intracranial pressure probe has a simple structure and a small size, can simultaneously monitor intracranial pressure and temperature, and has high accuracy and good stability. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0016] Figure 1 This is an overall structural diagram of the packaging structure of the intracranial pressure probe (without thermistor or temperature measurement chip) according to an embodiment of the present invention;

[0017] Figure 2 It is an overall structural diagram of the packaging structure of the intracranial pressure probe (with a thermistor or a temperature measurement chip) according to an embodiment of the present invention;

[0018] Figure 3 is a top view of an intracranial pressure probe according to an embodiment of the present invention;

[0019] Figure 4 is a schematic diagram of a chip retaining bracket of an intracranial pressure probe according to an embodiment of the present invention;

[0020] In the figure: 101, shell, 102, hemispherical head, 103, open nozzle, 104, window, 105, groove, 201, pressure chip, 202, coating, 203, chip pad, 204, glue 1, 205, glue 2, 206, epoxy resin glue, 207, insulation layer, 301, wire, 302, temperature measuring element, 401, hollow catheter, 501, chip stop bracket. DETAILED DESCRIPTION

[0021] The following will be combined with the accompanying drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field belong to the scope of protection of the present invention.

[0022] Example 1

[0023] like Figure 1 As shown, the packaging structure of the intracranial pressure probe (for intracranial pressure monitoring) according to the embodiment of the present invention includes a shell 101, the shell 101 is hollow inside, a pressure chip 201 and a chip stop bracket 501 composed of a wire 301 (enameled wire) connected to the pressure chip are installed in the shell 101, one end of the shell 101 is a sealed hemispherical head 102 made of the same material as the shell, and the other end is an open pipe mouth 103, the open pipe mouth 103 is fixedly connected to the hollow catheter 401 with epoxy resin glue 206, a window 104 larger than the pressure chip 201 is opened on the shell 101, and a groove 1 is provided on the inner wall of the shell just below the window 104 05, the inner wall of the shell is provided with a non-conductive insulating layer 207, the wire 301 connected to the pressure chip 201 passes through the inside of the hollow catheter 401 and is fixed with glue 205 at the rear edge of the groove 105, the pressure chip 201 is fixedly connected and sealed with glue 204 (medical glue) around the window 104 (perpendicular to the pressure sensing surface of the pressure chip), and is suspended at the window 104, the pressure chip 201 is provided with a coating 202, and the coating is seamlessly connected with the glue 204 around the window 104 that fixes the chip, the wire 301 is connected to the external circuit through the hollow catheter 401, and the top view of the intracranial pressure probe is as shown in Figure 3 shown.

[0024] like Figure 4As shown, one end of the wire 301 is directly hot-pressed and welded to the chip pad 203 and bent into a Π shape to form a chip stop bracket 501. The wire 301 is fixed to the shell with glue 205 in the rear edge of the groove away from the probe hemispherical head end. After the pressure chip 201 and the wire 301 are fixed with glue, they are not in contact with the inner wall of the shell 101 on all sides and are in a freely suspended state at the window 104.

[0025] Example 2

[0026] like Figure 2 As shown, the packaging structure of the intracranial pressure probe (for monitoring intracranial pressure and intracranial temperature) according to the embodiment of the present invention includes a shell 101, the shell 101 is hollow inside, and a pressure chip 201, a chip stop bracket 501 composed of a wire 301 (enameled wire) connected to the pressure chip, a temperature measuring element 302 (thermistor or temperature measuring chip) and a wire 301 connected to the temperature measuring element 302 are installed in the shell 101. One end of the shell 101 is a sealed hemispherical head 102 made of the same material as the shell, and the other end is an open pipe mouth 103. The open pipe mouth 103 is fixedly connected to the hollow catheter 401 with epoxy resin glue 206. The shell 101 is provided with a window 104 larger than the pressure chip 201. A groove 105 is provided on the inner wall of the shell just below the window 104, and a non-conductive insulating layer 207 is provided on the inner wall of the shell. The wire 301 connected to the pressure chip 201 and the wire 301 connected to the temperature measuring element pass through the inside of the hollow catheter 401 and are fixed with glue 205 at the rear edge of the groove 105. The temperature measuring element 302 is placed below the pressure chip 201 (for placement of an intracranial pressure probe with a temperature measuring function), and the pressure chip 201 is fixedly connected and sealed with glue 204 around the window 104 (perpendicular to the pressure sensing surface of the pressure chip). A coating 202 is provided on the pressure chip 201, and the coating 202 is seamlessly connected with the glue 204 that fixes the chip around the window 104.

[0027] One end of the wire 301 is directly hot-pressed and welded to the chip pad 203 and bent into a Π shape. The wire 301 is fixed to the shell with glue 205 in the rear edge of the groove away from the probe hemispherical head end. After being fixed with glue, the pressure chip 201, the temperature measuring element 302 and the wire 301 are not in contact with the inner wall of the shell 101 on all sides, and are in a freely suspended state at the window 104.

[0028] In order to facilitate understanding of the above technical solutions of the present invention, the above technical solutions of the present invention are described in detail below through specific usage methods.

[0029] In specific use, the pressure chip and temperature measuring element can also be various sensors that can sense changes in the external boundary environment (such as pressure, temperature, pH value, etc.) and generate electrical signal outputs. The probe can be surgically implanted into the human body to measure various physiological signals, such as intracranial pressure, intracranial temperature, etc.

[0030] The housing 101 is required to have a certain degree of rigidity to provide good protection for the internal pressure chip 201 and the temperature measuring element 302, and to prevent the entire probe from being scrapped due to impact and collision caused by external stress. The housing 101 should be made of biocompatible materials, such as polymer plastics, titanium alloys, stainless steel, ceramics, etc. When implanted, the probe needs to pass through the surface of the human body to reach the internal tissue. In order to prevent damage to the human tissue and increase the pain of the patient, the probe housing should be made into a smooth curved surface without edges and corners. Figure 1 In the example given, the end of the shell is connected to one end of the hollow conduit. A window is opened in the middle of the shell 101, and the function of this window is to allow the sensing surface of the pressure chip 201 to directly contact the external environment to ensure the accuracy of the measurement;

[0031] The chip stop bracket 501 is formed by a wire (enameled wire) 301, one end of the wire is directly hot-pressed and welded to the chip pad 203 and bent into a Π shape, and the wire is fixed to the shell with glue in the rear edge of the groove away from the probe hemisphere head end. After the front chip and the chip wire are fixed with glue, they are not in contact with the inner wall of the shell and are in a free floating state at the window. This Π-shaped structure should have a certain strength, not only can it serve as a bracket to make the pressure chip naturally suspended, but also can ensure that the pressure chip will not be affected when the external catheter of the intracranial pressure probe is bent or pulled.

[0032] The inner wall of the housing 101 is provided with a non-conductive insulating layer 207, and the insulating layer may be surface treated by electroplating, coating or the like;

[0033] The pressure chip 201 is fixedly connected and sealed with the window 104 by glue 204 perpendicular to the pressure sensing surface of the chip, and is suspended at the window 104. Glue 204 can be selected from various medical grade glues, such as two-component UV glue, RTV, etc. Different glues have different curing properties and water absorption properties. Suitable glue can be selected according to the specific characteristics of the pressure chip measuring physiological signals and accuracy requirements;

[0034] The coating 202 is a coating material on the surface of the pressure chip to protect the chip and prevent the body tissue fluid from corroding the pressure chip and affecting the measurement accuracy. The coating 202 should have high dielectric strength, good water vapor penetration resistance and other characteristics. Materials such as Parylene, epoxy resin, and silicone resin can be used. The coating 202 is applied after the hot pressing process is completed.

[0035] The wire (enameled wire) 301 is connected to the external circuit through the hollow conduit 401. The hollow conduit 401 is used to protect the circuit connection wire (enameled wire) and also serves as an airway. The material should have a certain hardness and elasticity and be difficult to bend to prevent blocking the airway.

[0036] To sum up, with the help of the above-mentioned technical scheme of the present invention, the intracranial pressure probe of the present invention utilizes the chip's own wires to form the structure of the chip stop bracket, the chip wires are directly hot-pressed and welded to the chip, and the packaging structure is simplified, which effectively solves the problem of the bending and pulling of the external catheter of the intracranial pressure probe affecting the measurement accuracy during use; the suspension structure of the chip stop bracket is utilized to effectively avoid the measurement error caused by thermal expansion deformation caused by ambient temperature; the non-conductive insulating layer arranged on the inner wall of the shell is utilized to well solve the measurement error caused by static electricity and human bioelectricity; the structure is simple, the size is small, and it can monitor intracranial pressure and temperature at the same time, with high accuracy and good stability.

[0037] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. An intracranial pressure probe, characterized in that: The invention comprises a shell (101), one end of the shell (101) is connected to a hemispherical head (102), the other end of the shell (101) is provided with an open pipe mouth (103), the open pipe mouth (103) is fixedly connected to a hollow conduit (401), a window (104) is provided at the top of the shell (101), a pressure chip (201) is provided inside the shell (101), the pressure chip (201) is located below the window (104), the pressure chip (201) is fixedly connected and sealed to the window (104) by glue (204), the pressure chip (201) is connected to a wire (301), the wire (301) passes through the hollow conduit (401), and a groove (105) is provided on the inner wall of the shell below the window (104). The wire (301) is fixedly connected to the rear edge of the groove (105) by means of glue (205); a temperature measuring element (302) is provided below the pressure chip (201); the temperature measuring element (302) is connected to the wire (301); the pressure chip (201) is hot-pressed welded to one end of the wire (301) by means of a chip pad (203); the wire (301) connected to the pressure chip (201) is in a Π shape, forming a chip stop bracket (501); the pressure chip (201), the temperature measuring element (302), and the wire (301) are not in contact with the inner wall of the shell, and are in a freely suspended state at the window (104); the temperature measuring element (302) is a thermistor or a temperature measuring chip; and an insulating layer (207) is provided on the inner wall of the shell (101).

2. The intracranial pressure probe according to claim 1, characterized in that: A coating (202) is provided on the top of the pressure chip (201), and the coating (202) is seamlessly connected to the glue 1 (204).

3. The intracranial pressure probe according to claim 1, characterized in that: The wire (301) passes through the hollow tube (401) and is connected to an external circuit.

4. The intracranial pressure probe according to claim 1, characterized in that: The hollow conduit (401) is connected to the open tube opening (103) via epoxy resin glue (206).

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