Aerosol generating system and aerosol generating method, inflammation therapeutic device and application thereof

Abstract

The present invention discloses an aerosol generating system and an aerosol generating method, an inflammation therapeutic device and its application. The aerosol generating system includes a discharge unit, a fluid unit and a mixing cavity; the discharge unit includes a discharge generator, a voltage delivery device and a voltage release port connected in sequence; the voltage release port is located in the mixing cavity; the fluid unit includes a storage device and a fluid flow chamber; the storage device is provided with a fluid release port, and the side wall of the fluid flow chamber is connected to the storage device through the fluid release port; one end of the fluid flow chamber is provided with an air inlet, and the other end is connected to the mixing cavity. The system provided by the present invention has a highly efficient bactericidal and anti-inflammatory effect, uses less reagents, has lower costs, and can reduce the toxic hazards of the antibacterial agent itself.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and in particular to an aerosol generating system and an aerosol generating method, an inflammation therapeutic device including the aerosol generating system, and applications thereof. Background Art

[0002] In our daily lives, infectious inflammations caused by biological pathogens such as bacteria, viruses, rickettsia, mycoplasma, fungi and parasites often trouble people, and the pain and itching caused by these inflammations seriously disrupt people's lives.

[0003] At present, in addition to oral anti-inflammatory drugs, the most effective method for treating the above-mentioned inflammation is to eliminate the pathogens in the inflammatory area in time. Among them, the pathogens in the inflammatory area can be eliminated by directly applying antibacterial agents. At the same time, the non-direct contact gasification drug application method can significantly increase the specific surface area of ​​the anti-inflammatory effect. However, the widespread use of antibacterial agents will lead to increased bacterial resistance, and over time, the ideal antibacterial effect can no longer be achieved. Summary of the invention

[0004] In view of the above problems existing in the prior art, the present invention provides an aerosol generating system and generating method, an inflammation treatment device including the aerosol generating system and its application. The aerosol generating system of the present invention can generate negative ions by ionizing gases such as air or oxygen, and can also ionize gaseous or liquid antibacterial agents to obtain a mixed aerosol of ionized antibacterial agents and negative ions, and achieves a highly efficient bactericidal and anti-inflammatory effect through the synergistic effect of the two, and the effect of the synergistic effect is better than the effect that can be achieved when using either one alone.

[0005] A first aspect of the present invention provides an aerosol generating system, the aerosol generating system comprising a discharge unit, a fluid unit and a mixing chamber;

[0006] The discharge unit comprises a discharge generator, a voltage delivery device and a voltage release port which are connected in sequence; the voltage release port is located in the mixing cavity;

[0007] The fluid unit includes a storage device and a fluid flow chamber; a fluid release port is provided on the storage device, and the side wall of the fluid flow chamber is connected with the storage device through the fluid release port; an air inlet is provided at one end of the fluid flow chamber, and the other end is connected with the mixing chamber.

[0008] According to some embodiments of the aerosol generating system of the present invention, the storage device is a gaseous antibacterial agent container and / or a liquid antibacterial agent container.

[0009] According to some embodiments of the aerosol generating system of the present invention, when the storage device is a liquid antibacterial agent container, the fluid release port is an atomizer nozzle. The atomizer nozzle can disperse the liquid antibacterial agent into tiny droplets, which are convenient for subsequent input into the mixing cavity and ionization.

[0010] According to some embodiments of the aerosol generating system of the present invention, when the storage device is a gaseous antibacterial agent container, the fluid release port is a gas release port.

[0011] According to some embodiments of the aerosol generating system of the present invention, the discharge generator is externally connected to a power supply. Preferably, the discharge generator is a corona discharge generator. Further preferably, the corona discharge generator includes a circuit integration box, on which a positive power input line and a negative power input line are provided, and the positive power input line and the negative power input line are respectively connected to the power supply to achieve circuit connectivity.

[0012] According to some embodiments of the aerosol generating system of the present invention, the voltage transmission device is a high voltage output wire.

[0013] According to some embodiments of the aerosol generating system of the present invention, the mixing chamber is made of a non-conductive material.

[0014] According to some embodiments of the aerosol generating system of the present invention, the system further comprises a fluid delivery device, and the fluid flow chamber and the mixing cavity are connected through the fluid delivery device.

[0015] According to some embodiments of the aerosol generating system of the present invention, the system further comprises an air pump, and the air pump is connected to the air inlet.

[0016] According to some embodiments of the aerosol generating system of the present invention, the system further comprises an aerosol nozzle, and the aerosol nozzle is disposed on the mixing chamber.

[0017] According to a preferred embodiment of the aerosol generating system of the present invention, the air inlet is connected to the fluid flow chamber via a first joint, and the fluid flow chamber is connected to the fluid delivery device via a second joint.

[0018] After the power is turned on, the discharge unit in the present invention ionizes the surrounding gas to generate negative ions through the electric field generated by the voltage release port. At the same time, it can also serve as an ionization source to ionize the fluid input from the fluid flow chamber and mix it in the mixing cavity to obtain a mixed aerosol of ionized fluid and negative ions.

[0019] In a specific embodiment of the present invention, a corona discharge generator is used as a discharge generator, and a liquid antibacterial agent and / or a gaseous antibacterial agent is selected as the fluid. In this specific embodiment, in addition to being able to generate negative ions, the corona discharge generator can also be used as an ion source to ionize the antibacterial agent. Therefore, under the dual function of the corona discharge generator, the ionized antibacterial agent can be simultaneously generated and mixed with negative ions to form a gaseous sol. The mixed gaseous sol has the bactericidal effect of both. In addition, the ionized antibacterial agent can significantly improve the efficacy of the antibacterial agent. The principle is: relative to non-charged antibacterial agents, due to electrostatic effects, ionized antibacterial agents can be more easily attached and captured by bacteria; ionized antibacterial agents are easy to form a hydration layer around them. For example, molecules wrapped by the hydration layer are more likely to penetrate the outer membrane of Gram-negative bacteria (low phospholipid content), thereby contacting the bacterial inner membrane (i.e., cytoplasmic membrane) and lysing the inner membrane to kill bacteria. On the contrary, the outer membrane of Gram-negative bacteria is a barrier to normal antibacterial agents (lipid soluble).

[0020] In the present invention, the antibacterial process of the ionized antibacterial agent and the negative ion is not carried out in isolation, and there is a synergistic effect between the antibacterial and antibacterial processes of the two, which is better than the effect that one of the two substances can play independently, and thus a smaller dose of antibacterial agent can be used to achieve a higher bactericidal efficiency. In different embodiments of the present invention, when the above-mentioned aerosol generating system is used for the treatment of inflammation, it has a high bactericidal efficiency, saves the amount of antibacterial agent used, thereby saving costs, and reduces the toxic hazards caused by the antibacterial agent itself.

[0021] A second aspect of the present invention provides an aerosol generating method according to the above-mentioned aerosol generating system, the method comprising the following steps:

[0022] Step A, starting the fluid release port to release fluid, and the fluid is sent into the fluid flow chamber through the side wall of the fluid flow chamber;

[0023] Step B, sending gas into the fluid flow chamber from the gas inlet, and the gas carries the fluid into the mixing chamber;

[0024] Step C: starting the discharge generator, and the voltage release port generates an electric field in the mixing cavity.

[0025] According to some embodiments of the method of the present invention, the fluid is a gaseous antibacterial agent and / or a liquid antibacterial agent. In different embodiments of the present invention, the types of gaseous antibacterial agents and liquid antibacterial agents are not limited, and different gaseous antibacterial agents and liquid antibacterial agents can be selected according to different pathogens.

[0026] According to some embodiments of the method described in the present invention, when a liquid antibacterial agent is used, the fluid release port is preferably an atomizer nozzle, so that the liquid antibacterial agent is dispersed into tiny droplets for subsequent input into the mixing chamber and ionization.

[0027] According to some embodiments of the method of the present invention, the gaseous antibacterial agent is preferably ozone and / or volatile essential oil. The liquid antibacterial agent is preferably ethanol and / or quaternary ammonium salt.

[0028] In different embodiments of the present invention, different antibacterial agents can be selected according to different antibacterial purposes. For example, alcohol organic antibacterial agents such as ethanol in the present invention can remove lipid substances in pathogenic bacteria biofilm and denature proteins, and the most commonly used alcohol organic antibacterial agent is ethanol with a mass concentration of 75%. Moreover, the quaternary ammonium salt antibacterial agent in the present invention can adsorb negatively charged pathogenic microorganisms, destroy the cell wall structure of microorganisms, and cause the contents therein to leak out. At the same time, the quaternary ammonium salt antibacterial agent also has the effect of inhibiting the activity of pathogenic bacteria oxidase and dehydrogenase, etc.

[0029] According to some embodiments of the method of the present invention, the gas is oxygen and / or nitrogen. Preferably, the gas is a mixed gas of oxygen and nitrogen. Further preferably, in the mixed gas of oxygen and nitrogen, the volume ratio of oxygen is 28%. In some embodiments of the present invention, the type of gas introduced is not limited. From the perspective of cost and feasibility, the gas can be selected from air.

[0030] According to some embodiments of the method of the present invention, the mixing cavity is made of a non-conductor material, which can prevent the electric field generated by the voltage release port from being conducted through the mixing cavity. Preferably, the material for preparing the mixing cavity is selected from at least one of polyvinyl fluoride, nylon, and organic glass.

[0031] According to some embodiments of the method of the present invention, the local intensity of the electric field is ≥20kV / cm. In different embodiments of the present invention, the input voltage of the discharge generator is not limited, because the electric field is a non-uniform electric field, as long as the local intensity of the electric field is ≥20kV / cm.

[0032] In the present invention, after the gas is input into the air inlet by the air pump, it enters the fluid flow chamber through the air inlet, and the gas carries the fluid therein into the mixing cavity. In the mixing cavity, after the discharge generator is started, the voltage release port at the end thereof releases a strong electric field in the mixing cavity to ionize the surrounding gas to generate negative ions. At the same time, the strong electric field can also be used as an ionization source to ionize the fluid therein, thereby obtaining a mixed aerosol of ionized fluid and negative ions.

[0033] In a specific embodiment of the present invention, the fluid is selected from a gaseous antibacterial agent and / or a liquid antibacterial agent, so that the method has a bactericidal and anti-inflammatory effect. The mixed aerosol obtained in this specific embodiment is a mixed aerosol of ionized antibacterial agent and negative ions, and has a high efficiency of bactericidal and anti-inflammatory ability.

[0034] In the present invention, the discharge generator is a corona discharge generator. After the corona discharge generator is powered on, the voltage release port at the end generates a strong electric field to ionize the nearby gas, which can be air or a high-purity gas input by an air pump, or a mixed gas of air and at least one high-purity gas.

[0035] The specific ionization process is as follows: the strong electric field of the voltage release port can cause the free electrons in the air to collide violently with oxygen molecules, generating oxygen free radicals. - and superoxide radicals·O 2 - , the reaction process is shown in formula (1) and formula (2):

[0036] e+O 2 =·O - +O (1)

[0037] ·O - +O 2 =·O 2 - +O (2)

[0038] Oxygen free radicals - and superoxide radicals·O 2 - Can continue to react with NO in the air 2 and CO 2 The reaction produces NO 3 - , HCO 3 - , CO 3 - and CO 4 - In addition, the negative ions produced by this process will attract the positive polarity ends (i.e. hydrogen atoms) of free water molecules in the air to form hydrates, such as CO 3 - ·H 2 O, HCO 3 - ·H 2 O、NO 3 - ·H 2 O and CO 4 - ·H 2 O. For ease of description, n is used in the present invention.- It represents the general term for the negative ions, namely n - For O - , ·O 2 - 、NO 3 - , CO 3 - , HCO 3 - , CO 4 - , CO 3 - ·H 2 O, HCO 3 - ·H 2 O、NO 3 - ·H 2 O and CO 4 - ·H 2 O and other negative ions.

[0039] The process of ionizing the antibacterial agent molecules (M) by the corona generator is shown in formula (3):

[0040] e+M=M - (3)

[0041] The non-high-energy free electrons are captured by the antibacterial agent molecules to form ions M - Similarly, M - It can also form hydrates M - ·H 2 O.

[0042] According to some embodiments of the method of the present invention, the n - and M - ·H 2 The aerosol formed by the mixture of O can penetrate the outer cell membrane of Gram-negative bacteria to reach the inner cell membrane of the bacteria. Specifically, the antibacterial mechanism of the mixed aerosol is: (1) acting on the protease or other biologically active substances required for biochemical reactions. (2) acting on genetic material DNA or other genetic particle structures. (3) acting on the biofilm system or cell wall. The present invention does not limit the type of bacteria. In different embodiments of the present invention, different antibacterial agents can be selected specifically for different types of bacteria.

[0043] Ionized antibacterial agents can also have the antibacterial effect of negative ions.

[0044] In some embodiments of the present invention, the antibacterial mechanism of negative ions against Gram-positive bacteria is as follows:

[0045]

[0046] First, the negative ions tend to attack the carbonyl groups on the tetrapeptide chains and pentaglycine bridges that constitute the main framework of the pathogen cell wall, as shown in reaction equations (4) and (5). - Through nucleophilic addition and interaction with the C=O bond, a tetrahedral intermediate is generated, i.e., the product of reaction formula (4). Then, the tetrahedral intermediate decomposes, the peptide bond breaks, and the process of reaction formula (5) occurs.

[0047] Then, the skeleton of the pathogen cell wall breaks down, leaving only the polysaccharide skeleton, which means that the pathogen's protective layer has been destroyed, making the cell more vulnerable. - Through cell transfer, it further attacks the cell membrane. Subsequently, the reaction between the negative ion and the cell membrane also occurs on the phospholipid molecules. Among them, the phospholipid molecules are the basic components of the stable membrane structure. Through the nucleophilic addition reaction (6), the negative ion n - Attacks the =O group, resulting in damage to the ester bond to produce reaction (7).

[0048] At the same time, negative ions n - It is also easy to attack the phosphate bond P=O on the phospholipids in the intracellular membrane, resulting in reaction formula (8). After its adduct, the skeleton is decomposed, resulting in reaction formula (9).

[0049]

[0050]

[0051] In the present invention, the antibacterial process of the ionized antibacterial agent and the negative ion is not carried out in isolation, and there is a synergistic effect between the antibacterial and antibacterial processes of the two, and the synergistic effect is better than the effect that one of the two substances can play independently. In different embodiments of the present invention, when the above-mentioned aerosol generation method is used for inflammation treatment, it has a high bactericidal efficiency, saves the amount of antibacterial agent used, thereby saving costs, and reduces the toxic hazards caused by the antibacterial agent itself.

[0052] A third aspect of the present invention provides an inflammation treatment device, which includes the above-mentioned aerosol generating system.

[0053] According to some embodiments of the inflammation therapeutic apparatus of the present invention, the therapeutic apparatus further comprises a cleaning device having a cleaning liquid inlet, a cleaning liquid flow channel and a cleaning liquid nozzle.

[0054] According to some embodiments of the inflammation therapeutic apparatus of the present invention, the therapeutic apparatus further comprises a drying device having a drying gas inlet, a drying gas flow channel and a drying gas nozzle.

[0055] In the present invention, the cleaning device and the drying device can be used to clean and dry the affected area before and after treatment, which can better ensure the anti-inflammatory and sterilization effects and reduce the probability of recurrence of infection.

[0056] According to some embodiments of the inflammation treatment device of the present invention, the treatment device further includes a control device, which includes a motor, a rotating screw and a translation platform. The translation platform is provided with the aerosol nozzle, the cleaning liquid nozzle and the dry gas nozzle. The motor is electrically connected to the rotating screw and is used to control the rotation of the rotating screw. The rotating screw is used to control the translation platform to translate. The translation platform is used to switch the aerosol nozzle, the cleaning liquid nozzle and the dry gas nozzle to work.

[0057] According to some embodiments of the inflammation treatment apparatus of the present invention, the control device further comprises a frame, and the frame is used to fix the motor, the rotating screw and the translation platform.

[0058] The present invention does not limit the type of control device. For example, the control device in the present invention uses an electric control translation stage, which can be self-made according to needs or purchased from a manufacturer. For example, the electric control translation stage can be purchased from FUYU electric CNC linear guide slide of Chengdu Fuyu Technology Co., Ltd., and the specific model is FSL80.

[0059] According to some embodiments of the inflammation therapeutic device described in the present invention, the therapeutic device also includes an assembly cavity, in which the aerosol generating system, the cleaning device, the drying device and the control device are disposed, and one end of the assembly cavity is open, and the translation platform is disposed directly below the opening.

[0060] The inflammation treatment device provided by the present invention generates a mixed aerosol of ionized antibacterial agent and negative ions through an aerosol generating system to treat inflammation of the affected area. By controlling the rotation of the rotating screw in the control device, the aerosol nozzle, cleaning liquid nozzle and dry gas nozzle on the translation stage are switched to work in turn, thereby realizing the functions of sterilization and anti-inflammation, cleaning and drying respectively.

[0061] In a specific embodiment of the present invention, if there is impurity in the inflamed area, the device can be switched to a cleaning device to clean the affected area first, and then switched to a drying device to dry it, and each cleaning action must be followed by a drying process, and then switched to an aerosol nozzle to sterilize and reduce inflammation of the affected area, and then cleaning and drying are performed, and each sterilization and reduction of inflammation action must be followed by a cleaning and drying process, thereby achieving high efficiency in sterilization and reduction of inflammation, saving the use of antibacterial agents, reducing the toxic hazards caused by the antibacterial agents themselves, saving costs, and achieving the lowest probability of recurrence of infection through the cleaning and drying process.

[0062] The fourth aspect of the present invention provides an application of the above-mentioned aerosol generating system, the above-mentioned inflammation therapeutic device or the above-mentioned aerosol generating method in a local inflammation therapeutic device, preferably in a gynecological inflammation therapeutic device and / or a hemorrhoidal anal inflammation therapeutic device, but is not limited thereto.

[0063] Beneficial effects of the present invention:

[0064] 1. The antibacterial process of the mixed aerosol of ionized antibacterial agent and negative ion in the present invention is not carried out in isolation. There is a synergistic effect between the antibacterial and antibacterial processes of the two. The effect of the synergistic effect is better than the effect of one of the two substances acting alone, and can achieve a more extensive antibacterial effect.

[0065] 2. When the mixed aerosol of ionized antibacterial agent and negative ions provided by the present invention is used for the treatment of inflammation, it has a more efficient bactericidal efficiency, saves the amount of antibacterial agent used, thereby saving costs, and reduces the toxic hazards caused by the antibacterial agent itself.

[0066] 3. The inflammation treatment device provided by the present invention adopts an aerosol generating system, a cleaning device and a drying device to comprehensively treat the affected area, which can achieve the lowest probability of recurrent infection. BRIEF DESCRIPTION OF THE DRAWINGS

[0067] Figure 1 This is a schematic structural diagram of an aerosol generating system provided in Example 1 of the present invention.

[0068] Figure 2 This is a schematic structural diagram of an aerosol generating system provided in Example 2 of the present invention.

[0069] Figure 3 This is a schematic structural diagram of an aerosol generating system provided in Example 3 of the present invention.

[0070] Figure 4 This is a schematic diagram of the structure of an inflammation treatment device provided in Example 4 of the present invention.

[0071] Figure 5A schematic diagram of the structure of a control device, a cleaning device, a drying device and a circuit device in an inflammation treatment device provided in Example 4 of the present invention.

[0072] Description of reference numerals:

[0073] 1. Assembly cavity, 2. Control device, 3. Aerosol generating system, 4. Cleaning device, 5. Drying device, 6. Circuit device;

[0074] 201. Motor, 202. Rotating screw, 203. Frame, 204. Translation stage;

[0075] 311. Positive power input line, 312. Negative power input line, 313. Circuit integration box, 314. High voltage output wire, 315. Voltage release port;

[0076] 321. air inlet, 322. first interface, 323. fluid flow chamber, 324. second interface, 325. fluid delivery device, 326. mixing chamber, 327. aerosol nozzle;

[0077] 331. Liquid antibacterial agent container, 332. Atomizer nozzle;

[0078] 341. Gas antibacterial agent container, 342. Gas release port;

[0079] 401. cleaning liquid inlet, 402. third interface, 403. cleaning liquid flow channel, 404. fourth interface, 405. cleaning liquid nozzle;

[0080] 501. Drying gas inlet, 502. Fifth interface, 503. Drying gas flow channel, 504. Sixth interface, 505. Drying gas nozzle;

[0081] 601. Power adapter, 602. Electrical wires. DETAILED DESCRIPTION

[0082] In order to make the present invention easier to understand, the present invention will be described in detail below with reference to the accompanying drawings and embodiments. These drawings and embodiments are only for illustration and are not intended to limit the application scope of the present invention.

[0083] The equipment used in the present invention is as follows:

[0084] (1) The electric control translation stage is the FUYU electric CNC linear guide slide, model FSL80, produced by Chengdu Fuyu Technology Co., Ltd.

[0085] (2) The corona discharge generator is the product in CN201710285159.6.

[0086] [Example 1]

[0087] like Figure 1 , which is a schematic diagram of the structure of an aerosol generating system provided in this embodiment, comprising a discharge unit, a fluid unit and a mixing chamber 326. The mixing chamber 326 is made of polytetrafluoroethylene.

[0088] The discharge unit includes a positive power input line 311, a negative power input line 312, a circuit integration box 313, a high-voltage output line 314, and a voltage release port 315. The positive power input line 311 and the negative power input line 312 are arranged on the circuit integration box 313 for external power supply. The circuit integration box 313 and the voltage release port 315 are connected through the high-voltage output line 314. The voltage release port 315 is located in the mixing chamber 326, and is used to release a strong electric field after power is turned on, and ionize the air and other gases therein to generate negative ions.

[0089] The fluid unit includes a liquid antibacterial agent container 331, a gaseous antibacterial agent container 341 and a fluid flow chamber 323. Among them, an atomizer nozzle 332 is provided on the liquid antibacterial agent container 331, which is used to disperse the liquid antibacterial agent into tiny droplets. A gas release port 342 is provided on the gaseous antibacterial agent container 341. The side wall of the fluid flow chamber 323 is connected to the liquid antibacterial agent container 331 and the gaseous antibacterial agent container 341 through the atomizer nozzle 332 and the gas release port 342 respectively. In addition, an air inlet 321 is provided at one end of the fluid flow chamber 323, and the other end is connected to the mixing cavity 326 via a fluid conveying device 325. Among them, the air inlet 321 is externally connected to an air pump (not shown in the figure), and the air inlet 321 is connected to the fluid flow chamber 323 through a first joint 322, and the fluid flow chamber 323 is connected to the fluid conveying device 325 through a second joint 324.

[0090] The atomized liquid antibacterial agent sprayed from the liquid antibacterial agent container 331 and the gaseous antibacterial agent sprayed from the gaseous antibacterial agent container 341 are input into the mixing cavity 326 via the fluid delivery device 325, and are ionized under the action of the strong electric field released by the voltage release port 315 to obtain an ionized antibacterial agent, which then generates a mixed aerosol with negative ions. The mixed aerosol is sprayed from the aerosol nozzle 327 to sterilize and reduce inflammation on the affected area.

[0091] [Example 2]

[0092] like Figure 2 As shown, the structure of the aerosol generating system of this embodiment is the same as that of the embodiment 1, except that: the liquid antibacterial agent container 331 and the atomizer nozzle 332 are not provided in this embodiment.

[0093] [Example 3]

[0094] like Figure 3As shown, the structure of the aerosol generating system of this embodiment is the same as that of the embodiment 1, except that: the gaseous antibacterial agent container 341 and the gas release port 342 are not provided in this embodiment.

[0095] [Example 4]

[0096] like Figure 4 As shown, it is a schematic diagram of the structure of an inflammation treatment device provided in this embodiment, including an assembly cavity 1, a control device 2, an aerosol generating system 3, a cleaning device 4, a drying device 5 and a circuit device 6. Among them, the structure of the aerosol generating system is the same as that described in Example 1, and will not be repeated here.

[0097] like Figure 5 As shown, the cleaning device 4 has a cleaning liquid inlet 401, a cleaning liquid channel 403 and a cleaning liquid nozzle 405, wherein the cleaning liquid inlet 401 and the cleaning liquid channel 403 are connected via a third interface 402, and the cleaning liquid channel 403 and the cleaning liquid nozzle 405 are connected via a fourth interface 404.

[0098] The drying device 5 has a drying gas inlet 501 , a drying gas channel 503 and a drying gas nozzle 505 , wherein the drying gas inlet 501 and the drying gas channel 503 are connected via a fifth interface 502 , and the drying gas channel 503 and the drying gas nozzle 505 are connected via a sixth interface 504 .

[0099] The control device 2 in this embodiment uses an electric control translation stage, wherein the electric control translation stage includes a motor 201, a rotating screw 202, a frame 203 and a translation stage 204. The frame 203 is used to fix the motor 201, the rotating screw 202 and the translation stage 204. The translation stage 204 is provided with an aerosol nozzle 327, a cleaning liquid nozzle 405 and a drying gas nozzle 505. The motor 201 is electrically connected to the rotating screw 202 to control the rotation of the rotating screw 202, and the rotating screw further controls the translation stage 204 to translate, thereby realizing the switching of the aerosol nozzle 327, the cleaning liquid nozzle 405 and the drying gas nozzle 505 to work in turn.

[0100] The circuit device 6 includes a power adapter 601 and a wire 602 connected thereto, and is used to provide power for the inflammation therapeutic device.

[0101] like Figure 4 As shown, the aerosol generating system 3, the cleaning device 4, the drying device 5, the control device 2 and the circuit device 6 are all arranged in the assembly cavity 1. In addition, one end of the assembly cavity 1 is open, and the translation stage 204 is located directly below the opening, so that the materials in the aerosol nozzle 327, the cleaning liquid nozzle 405 and the drying gas nozzle 505 can be sprayed toward the affected area.

[0102] [Example 5]

[0103] This embodiment provides an aerosol generating system as shown in Embodiment 1 for use in a sterilization process of Gram-negative bacteria, comprising the steps of:

[0104] Step A: liquid ethanol antibacterial agent with a mass concentration of 75% is used, and atomized ethanol is sprayed out through the atomizer nozzle 332 and sent into the fluid flow chamber 323.

[0105] Step B: A mixed gas of oxygen and nitrogen with a volume ratio of 28% is delivered into the fluid flow chamber 323 through the air inlet 321 by an air pump, and the atomized ethanol is carried into the mixing chamber 326 .

[0106] Step C: the circuit integration box 313 is turned on, and the voltage release port 315 generates a corona induction electric field with a local electric field strength of 20 kV / cm in the mixing cavity 326 .

[0107] Under the action of the strong electric field, the atomized ethanol undergoes an ionization reaction to obtain ionized ethanol, and the oxygen undergoes a negative ion reaction to obtain oxygen free radicals·O - and superoxide radicals·O 2 - The negative ions are mixed in the mixing chamber 326 to obtain a mixed aerosol. The mixed aerosol is used to treat pathogens.

[0108] In summary, the aerosol generating system and inflammation treatment device provided by the present invention have highly efficient bactericidal and anti-inflammatory effects, can effectively solve the problem of increased drug resistance of pathogens due to the widespread use of antibacterial agents, and have a wider antibacterial effect, use less reagents, and have lower costs. It can also reduce the toxic hazards of the antibacterial agents themselves and significantly reduce the chance of recurrent infection.

[0109] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this field, under the technical enlightenment provided by the present invention, as common knowledge in the field, other equivalent variations and improvements can also be made, which should also be regarded as the protection scope of the present invention.

Claims

1. An aerosol generating system, It is characterized in that The aerosol generating system comprises a discharge unit, a fluid unit and a mixing chamber; The discharge unit comprises a discharge generator, a voltage delivery device and a voltage release port connected in sequence; the voltage release port is located in the mixing chamber; when the discharge generator is started, the voltage release port at the end thereof releases a strong electric field in the mixing chamber to ionize the surrounding gas and generate negative ions; The fluid unit comprises a storage device and a fluid flow chamber; the storage device is provided with a fluid release port, and the side wall of the fluid flow chamber is connected with the storage device through the fluid release port; one end of the fluid flow chamber is provided with an air inlet, and the other end is connected with the mixing chamber; The storage device is a gaseous bacteriostatic agent container and / or a liquid bacteriostatic agent container. When the storage device is a liquid bacteriostatic agent container, the fluid release port is an atomizer nozzle.

2. The aerosol generating system according to claim 1, It is characterized in that The discharge generator is externally connected to a power source; and / or, The mixing chamber is made of non-conductive material.

3. The aerosol generating system according to claim 2, It is characterized in that The discharge generator is a corona discharge generator.

4. The aerosol generating system according to claim 3, It is characterized in that The voltage transmission device is a high voltage output wire.

5. An aerosol generating system according to any one of claims 1 to 4, It is characterized in that The system further comprises a fluid delivery device, through which the fluid flow chamber and the mixing chamber are connected; and / or, The system further comprises an air pump, the air pump being in communication with the air inlet; and / or, The system further comprises an aerosol nozzle, wherein the aerosol nozzle is arranged on the mixing chamber; and / or, The air inlet is connected to the fluid flow chamber via a first joint, and the fluid flow chamber is connected to the fluid delivery device via a second joint.

6. An aerosol generating method according to the aerosol generating system according to any one of claims 1 to 5, It is characterized in that The method comprises the following steps: Step A, starting the fluid release port to release fluid, and the fluid is sent into the fluid flow chamber through the side wall of the fluid flow chamber; Step B, sending gas into the fluid flow chamber from the gas inlet, and the gas carries the fluid into the mixing chamber; Step C, starting the discharge generator, and the voltage release port generates an electric field in the mixing cavity; The fluid is a gaseous bacteriostatic agent and / or a liquid bacteriostatic agent.

7. The aerosol generating method according to claim 6, It is characterized in that The gaseous antibacterial agent is ozone and / or volatile essential oil; and / or, The liquid antibacterial agent is ethanol and / or a quaternary ammonium salt; and / or, The mixing cavity is made of a non-conductive material; and / or, The local intensity of the electric field is ≥20 kV / cm.

8. The aerosol generating method according to claim 7, It is characterized in that The mixing cavity is made of at least one of polyvinyl fluoride, nylon and organic glass.

9. An inflammation treatment device, It is characterized in that The therapeutic apparatus comprises an aerosol generating system as described in any one of claims 1-5.

10. The inflammation treatment device according to claim 9, It is characterized in that The therapeutic apparatus further comprises a cleaning device, wherein the cleaning device comprises a cleaning liquid inlet, a cleaning liquid flow channel and a cleaning liquid nozzle; and / or, The therapeutic apparatus also includes a drying device, which has a drying gas inlet, a drying gas flow channel and a drying gas nozzle.

11. The inflammation treatment device according to claim 10, It is characterized in that The therapeutic apparatus also includes a control device, which includes a motor, a rotating screw and a translation platform; wherein the aerosol nozzle, the cleaning liquid nozzle and the dry gas nozzle are arranged on the translation platform; the motor is electrically connected to the rotating screw and is used to control the rotation of the rotating screw, the rotating screw is used to control the translation of the translation platform, and the translation platform is used to switch the aerosol nozzle, the cleaning liquid nozzle and the dry gas nozzle to work.

12. The inflammation treatment device according to claim 11, It is characterized in that The control device further comprises a frame, and the frame is used for fixing the motor, the rotating screw and the translation stage.

13. The inflammation treatment device according to claim 11 or 12, It is characterized in that The therapeutic device also includes an assembly cavity, in which the aerosol generating system, the cleaning device, the drying device and the control device are arranged. One end of the assembly cavity is open, and the translation platform is arranged directly below the opening.

14. A local inflammation treatment device, It is characterized in that The local inflammation treatment device comprises the aerosol generating system described in any one of claims 1-5.

15. A gynecological inflammation treatment device, It is characterized in that The gynecological inflammation therapeutic device comprises the aerosol generating system described in any one of claims 1-5.

16. A therapeutic device for hemorrhoidal anal inflammation, It is characterized in that The hemorrhoidal anal inflammation treatment device comprises the aerosol generating system described in any one of claims 1-5.

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