Method for detecting wall shear parameter, ultrasonic imaging system and readable storage medium

Abstract

Embodiments of the present application disclose a method for detecting wall shear parameter of a blood vessel, an ultrasonic imaging system and a computer readable storage medium. The method comprises: acquiring, by an ultrasonic probe, a first wall shear stress or a first wall shear rate of a to-be-detected position on a longitudinal section and a second wall shear stress or a second wall shear rate of the to-be-detected position on a transverse section; synthesizing a three-dimensional wall shear stress at the to-be-detected position according to the first wall shear stress and the second wall shear stress, or determining a three-dimensional wall shear rate of the to-be-detected position according to the first wall shear rate and the second wall shear rate; and displaying the three-dimensional wall shear stress or the three-dimensional wall shear rate of the to-be-detected position of the blood vessel wall. In this way, a user can perform clinical evaluation related to arteriosclerosis according to the size and direction of the displayed three-dimensional wall shear stress or three-dimensional wall shear rate, thereby improving the accuracy and repeatability of detection.

Description

Technical Field

[0001] This application relates to the field of ultrasound technology, and in particular to a method for detecting the wall shear parameters of blood vessels, an ultrasound imaging system, and a computer-readable storage medium. Background Technology

[0002] Wall shear stress (WSS) can be used in clinical research and assessment related to arteriosclerosis. Wall shear stress is related to the gradient of the blood flow velocity component along the tangential direction of the vessel wall near the measurement point. Calculating or detecting the WSS requires knowing the magnitude and direction of the blood flow velocity in the vessel to obtain its tangential velocity component value. A traditional detection method uses the Doppler principle to measure the longitudinal section of the vessel to obtain the WSS within that section. However, traditional methods only measure the WSS in a two-dimensional plane within the longitudinal section, failing to obtain WSS in other dimensions. This may result in the wall shear stress not being adequately reflected, affecting the accuracy of clinical research and assessment of arteriosclerosis. Summary of the Invention

[0003] This application provides a method for detecting blood vessel wall shear parameters, an ultrasound imaging system, and a computer-readable storage medium, which can improve the accuracy of detection.

[0004] The first aspect of this application provides a method for detecting blood vessel wall shear parameters, including:

[0005] The first ultrasound wave is emitted into the tissue containing blood vessels by an ultrasound probe, and the first ultrasound echo data is generated after receiving the first ultrasound echo returned by the tissue.

[0006] Based on the first ultrasound echo data, a longitudinal section ultrasound image of the blood vessel is obtained, and the test location on the vessel wall of the blood vessel in the longitudinal section ultrasound image is determined.

[0007] The ultrasound probe emits a third ultrasound wave into the tissue containing blood vessels and generates third ultrasound echo data after receiving the third ultrasound echo returned by the tissue.

[0008] The first vector velocity of blood flow in the blood vessel in the longitudinal section is determined based on the third ultrasound echo data.

[0009] The first wall shear stress or first wall shear rate at the test location on the longitudinal section is determined based on the first vector velocity.

[0010] The ultrasound probe emits a second ultrasound wave to the tissue containing blood vessels and generates second ultrasound echo data after receiving the second ultrasound echo returned by the tissue.

[0011] A cross-sectional ultrasound image of the blood vessel containing the location to be tested is obtained based on the second ultrasound echo data.

[0012] The ultrasound probe emits a fourth ultrasound wave into the tissue containing blood vessels and generates fourth ultrasound echo data after receiving the fourth ultrasound echo returned by the tissue.

[0013] The second vector velocity of blood flow in the blood vessel on the cross-section is determined based on the fourth ultrasound echo data.

[0014] The second wall shear stress or second wall shear rate at the measured location on the cross section is determined based on the second vector velocity.

[0015] The three-dimensional wall shear stress at the test location is determined based on the first wall shear stress and the second wall shear stress, or the three-dimensional wall shear rate at the test location is determined based on the first wall shear rate and the second wall shear rate.

[0016] This displays the three-dimensional wall shear stress or three-dimensional wall shear rate at the location to be measured.

[0017] A second aspect of this application provides a method for detecting blood vessel wall shear parameters, comprising:

[0018] The first ultrasound wave is emitted into the tissue containing blood vessels by an ultrasound probe, and the first ultrasound echo data is generated after receiving the first ultrasound echo returned by the tissue.

[0019] Based on the first ultrasound echo data, a longitudinal section ultrasound image of the blood vessel is obtained, and the test location on the vessel wall of the blood vessel in the longitudinal section ultrasound image is determined.

[0020] The first vector velocity of blood flow in the blood vessel in the longitudinal section is determined based on the first ultrasound echo data.

[0021] The first wall shear stress or first wall shear rate at the test location on the longitudinal section is determined based on the first vector velocity.

[0022] The ultrasound probe emits a second ultrasound wave to the tissue containing blood vessels and generates second ultrasound echo data after receiving the second ultrasound echo returned by the tissue.

[0023] A cross-sectional ultrasound image of the blood vessel containing the location to be tested is obtained based on the second ultrasound echo data.

[0024] The second vector velocity of blood flow in the blood vessel on the cross-section is determined based on the second ultrasound echo data.

[0025] The second wall shear stress or second wall shear rate at the measured location on the cross section is determined based on the second vector velocity.

[0026] The three-dimensional wall shear stress at the test location is determined based on the first wall shear stress and the second wall shear stress, or the three-dimensional wall shear rate at the test location is determined based on the first wall shear rate and the second wall shear rate.

[0027] This displays the three-dimensional wall shear stress or three-dimensional wall shear rate at the location to be measured.

[0028] A third aspect of this application provides a method for detecting blood vessel wall shear parameters, comprising:

[0029] The first ultrasound wave is emitted into the tissue containing blood vessels by an ultrasound probe, and the first ultrasound echo data is generated after receiving the first ultrasound echo returned by the tissue.

[0030] Based on the first ultrasound echo data, a cross-sectional ultrasound image of the blood vessel is obtained, and the test location on the vessel wall of the blood vessel in the cross-sectional ultrasound image is determined.

[0031] A second ultrasound wave is emitted into the tissue containing blood vessels by an ultrasound probe, and second ultrasound echo data is generated after receiving the second ultrasound echo returned by the tissue.

[0032] The vector velocity of blood flow in the blood vessel on the cross-section is determined based on the second ultrasound echo data.

[0033] The wall shear stress or wall shear rate at the measured location on the cross section is determined based on the vector velocity.

[0034] This displays the wall shear stress or wall shear rate at the measured location on the cross-section.

[0035] A fourth aspect of this application provides a method for detecting blood vessel wall shear parameters, comprising:

[0036] The first ultrasound wave is emitted into the tissue containing blood vessels by an ultrasound probe, and the first ultrasound echo data is generated after receiving the first ultrasound echo returned by the tissue.

[0037] Based on the first ultrasound echo data, a cross-sectional ultrasound image of the blood vessel is obtained, and the test location on the vessel wall of the blood vessel in the cross-sectional ultrasound image is determined.

[0038] The vector velocity of blood flow in the blood vessel on the cross-section is determined based on the first ultrasound echo data;

[0039] The wall shear stress or wall shear rate at the measured location on the cross section is determined based on the vector velocity.

[0040] This displays the wall shear stress or wall shear rate at the measured location on the cross-section.

[0041] The fifth aspect of this application provides a method for detecting blood vessel wall shear parameters, including:

[0042] The first ultrasound wave is emitted into the tissue containing blood vessels through an array probe, and the first ultrasound echo data is generated after receiving the first ultrasound echo returned by the tissue.

[0043] Based on the first ultrasound echo data, a three-dimensional ultrasound image of the blood vessel is obtained, and the test location on the blood vessel wall in the three-dimensional ultrasound image is determined.

[0044] The area array probe emits a second ultrasound wave into the tissue containing blood vessels and generates second ultrasound echo data after receiving the second ultrasound echo returned by the tissue.

[0045] The three-dimensional vector velocity of blood flow in the blood vessel is determined based on the second ultrasound echo data;

[0046] The three-dimensional wall shear stress or three-dimensional wall shear rate at the test location is determined based on the three-dimensional vector velocity.

[0047] This displays the three-dimensional wall shear stress or three-dimensional wall shear rate at the location to be measured.

[0048] The sixth aspect of this application provides a method for detecting blood vessel wall shear parameters, including:

[0049] The first ultrasound wave is emitted into the tissue containing blood vessels through an array probe, and the first ultrasound echo data is generated after receiving the first ultrasound echo returned by the tissue.

[0050] Based on the ultrasound echo data, a three-dimensional ultrasound image of the blood vessel is obtained, and the location to be tested on the vessel wall in the three-dimensional ultrasound image is determined.

[0051] The three-dimensional vector velocity of blood flow in the blood vessel is determined based on the first ultrasound echo data;

[0052] The three-dimensional wall shear stress or three-dimensional wall shear rate at the test location is determined based on the three-dimensional vector velocity.

[0053] This displays the three-dimensional wall shear stress or three-dimensional wall shear rate at the location to be measured.

[0054] A seventh aspect of this application provides an ultrasound imaging system, comprising:

[0055] probe;

[0056] A transmitting circuit that excites the probe to emit ultrasound waves from the tissue under test, which contains blood vessels;

[0057] A receiving circuit controls the probe to receive ultrasound echoes returned from the tissue under test to obtain ultrasound echo data;

[0058] A processor is configured to acquire the ultrasonic echo data, and when the processor executes a computer program stored in a memory, it is configured to implement some or all of the steps described in any of the methods of the first to sixth aspects of the embodiments of this application.

[0059] An eighth aspect of this application provides a computer-readable storage medium for storing a computer program for electronic data interchange, wherein the computer program causes a computer to perform some or all of the steps described in any of the methods of the first to sixth aspects of this application.

[0060] The aforementioned method for detecting vascular wall shear parameters, the ultrasound imaging system, and the computer-readable storage medium acquire three-dimensional wall shear stress or three-dimensional wall shear rate at the test location via an ultrasound probe. Thus, users can perform clinical assessments related to arteriosclerosis by displaying the magnitude and direction of the three-dimensional wall shear stress or three-dimensional wall shear rate, improving the accuracy and repeatability of the detection. Attached Figure Description

[0061] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0062] Figure 1 This is a schematic diagram of the hardware structure of an ultrasound imaging system in one embodiment of this application.

[0063] Figure 2 This is a flowchart of the method steps for detecting the wall shear parameters of blood vessels in one embodiment of this application.

[0064] Figure 3 This is a schematic diagram of a longitudinal section ultrasound image in one embodiment of this application.

[0065] Figure 4 This is a schematic diagram of a longitudinal section ultrasound image in another embodiment of this application.

[0066] Figure 5 This is a schematic diagram of a cross-sectional ultrasound image in one embodiment of this application.

[0067] Figure 6 This is a schematic diagram of obtaining the location to be measured in a cross-sectional ultrasound image according to one embodiment of this application.

[0068] Figure 7 This is a schematic diagram of the synthesis of three-dimensional wall shear stress in one embodiment of this application.

[0069] Figure 8 This is a schematic diagram of the velocity change curve of the measured position in the longitudinal section in one embodiment of this application.

[0070] Figure 9 This is a schematic diagram of the velocity change curve of the measured position at the cross section in one embodiment of this application.

[0071] Figure 10 This is a schematic diagram showing three-dimensional wall shear stress or three-dimensional wall shear rate in one embodiment of this application.

[0072] Figure 11 This is a flowchart of the steps of a method for detecting the wall shear parameters of blood vessels in another embodiment of this application.

[0073] Figure 12 This is a flowchart of the steps of a method for detecting the wall shear parameters of blood vessels in another embodiment of this application.

[0074] Figure 13 This is a schematic diagram showing three-dimensional wall shear stress in another embodiment of this application.

[0075] Figure 14 This is a block diagram of an ultrasound imaging system according to another embodiment of the application. Detailed Implementation

[0076] To enable those skilled in the art to better understand the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present application, and not all embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present application.

[0077] The terms "first," "second," etc., in the specification, claims, and accompanying drawings of this application are used to distinguish different objects, not to describe a specific order. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion. For example, a process, method, system, product, or apparatus that includes a series of steps or units is not limited to the listed steps or units, but may optionally include steps or units not listed, or may optionally include other steps or units inherent to these processes, methods, products, or apparatuses.

[0078] In this document, the term "embodiment" means that a particular feature, structure, or characteristic described in connection with an embodiment may be included in at least one embodiment of this application. The appearance of this phrase in various places throughout the specification does not necessarily refer to the same embodiment, nor is it a separate or alternative embodiment mutually exclusive with other embodiments. It will be explicitly and implicitly understood by those skilled in the art that the embodiments described herein can be combined with other embodiments.

[0079] Please see Figure 1 The diagram shows a hardware structure schematic of an ultrasound imaging system according to an embodiment of this application. The ultrasound imaging system 10 may include a probe 100, a transmitting circuit 102 connected to the probe 100, a receiving circuit 104 connected to the probe 100, a beamforming module 106, a signal processing module 108, an imaging processing module 110, and a display device 112. The receiving circuit 104, beamforming module 106, signal processing module 108, imaging processing module 110, and display device 112 are electrically connected sequentially. In this embodiment, the ultrasound imaging system 10 can acquire the three-dimensional wall shear stress or three-dimensional wall shear rate at the test location. This allows for clinical assessment related to arteriosclerosis by measuring the three-dimensional wall shear stress or three-dimensional wall shear rate at the test location, thereby improving the accuracy and repeatability of the detection. In one embodiment, the ultrasound imaging system 10 may also acquire the wall shear stress or wall shear rate at the location to be tested within the cross-section of the blood vessel, so that the user can perform clinical assessments related to arteriosclerosis based on wall shear stress or wall shear rate in other dimensions (such as wall shear stress or wall shear rate at the cross-section).

[0080] Please refer to the following: Figure 2 The diagram shows a flowchart of a method for detecting the wall shear parameters of a blood vessel in one embodiment of this application. The detection method includes the following steps:

[0081] In this embodiment, the probe 100 can be an ultrasonic probe, which can be a one-dimensional ultrasonic probe, such as a linear array probe, a convex array probe, or a phased array probe. Furthermore, the imaging processing module 110 can acquire the measured position 400 (shown in the image) through the ultrasonic probe. Figure 3The first wall shear stress or first wall shear ratio on the longitudinal section and the second wall shear stress or second wall shear ratio on the cross section are used to determine the three-dimensional wall shear stress at the test location 400 based on the first wall shear stress and the second wall shear stress, or to determine the three-dimensional wall shear ratio at the test location 400 based on the first wall shear ratio and the second wall shear ratio.

[0082] Step 200: A first ultrasound wave is emitted to the tissue containing blood vessels through an ultrasound probe, and first ultrasound echo data is generated after receiving the first ultrasound echo returned by the tissue.

[0083] Please refer to the following: Figure 3 The diagram shows a schematic of a longitudinal section ultrasound image in one embodiment of this application. Upon receiving the excitation timing sequence, the transmitting circuit 102 can transmit a first ultrasound wave to the tissue under test, including the blood vessel 40, via the probe 100, wherein the first ultrasound wave can be transmitted along the longitudinal axis of the blood vessel. After a certain delay, the probe 100 can receive the returned first ultrasound echo carrying information about the object being tested. The probe 100 can convert this first ultrasound echo into an electrical signal. The receiving circuit 104 receives the electrical signal generated by the probe 100 and sends the processed electrical signal (including but not limited to amplification, gain compensation, detection, noise filtering, and A / D conversion) to the beamforming module 106. The beamforming module 106 performs focusing delay, weighting, and channel summation on the electrical signal, and the signal processing module 108 performs related signal processing to generate the first ultrasound echo data.

[0084] Step 202: Obtain a longitudinal section ultrasound image of the blood vessel based on the first ultrasound echo data, and determine the location to be tested on the vessel wall of the blood vessel in the longitudinal section ultrasound image.

[0085] The imaging processing module 110 can generate a longitudinal section ultrasound image 500 of the blood vessel based on the first ultrasound echo data. For example, the imaging processing module 110 can perform different processing on the first ultrasound echo data according to the different imaging modes required by the user to obtain tissue image data of different modes. Then, after processing such as logarithmic compression, dynamic range adjustment, and digital scan transformation, different modes of ultrasound images are formed and displayed on the display device 112. The different modes of ultrasound images may include B-images, C-images, or other types of two-dimensional or three-dimensional ultrasound images. Since the first ultrasound wave is emitted along the longitudinal axis of the blood vessel 40, the longitudinal section ultrasound image 500 can be an ultrasound image of the longitudinal section of the blood vessel 40 (or an ultrasound image including the length direction of the blood vessel).

[0086] In this embodiment, the imaging processing module 110 can be used to determine the blood vessel wall 402 in the longitudinal section ultrasound image 500 and to obtain the position to be measured 400 on the blood vessel wall 402. For example, the imaging processing module 110 can display the longitudinal section ultrasound image 500 on the display device 112. Then, the user can observe the longitudinal section ultrasound image, confirm the position of the blood vessel wall 402 in the longitudinal section ultrasound image 500, and add a blood vessel wall marker at the position of the blood vessel wall 402 in the longitudinal section ultrasound image 500 through an input device (including but not limited to a mouse, buttons, touch screen, etc.), and set the position of the blood vessel wall marker as the position to be measured 400. The position to be measured may include one or more positions along the length direction of the blood vessel wall 402.

[0087] In other embodiments, the imaging processing module 110 may also use automatic identification to determine the blood vessel wall. For example, determining the blood vessel wall 402 in the longitudinal section ultrasound image 500 by the imaging processing module 110 includes: identifying regions in the longitudinal section ultrasound image 500 whose brightness is higher than a preset brightness threshold, and determining the regions whose brightness is higher than the aforementioned preset brightness threshold as the blood vessel wall 402. As another example, determining the blood vessel wall in the longitudinal section ultrasound image 500 by the imaging processing module 110 may also include: calculating the blood flow energy at the location of the blood vessel to be detected; locating the edge of the blood flow energy; and identifying regions in the longitudinal section ultrasound image 500 whose brightness is higher than the preset brightness threshold and are located at the edge of the blood flow energy, and determining the regions whose brightness is higher than the preset brightness threshold and are located at the edge of the blood flow energy as the blood vessel wall 402. The imaging processing module 110 may also compare the blood flow energy with an energy threshold to determine the location where the blood flow energy is lower than the energy threshold as the edge of the blood flow energy. Since not all ultrasound scans will show blood vessels in the scanning area, further judgment based on blood vessel energy can significantly improve the accuracy of determining the blood vessel wall 402.

[0088] The imaging processing module 110 defines and sets the test location 400 based on the aforementioned obtained blood vessel wall 402. The test location 400 can be a region within one or more location ranges on the blood vessel wall 402, including but not limited to one or more location regions on the anterior and / or posterior wall of the blood vessel 40, or a region within the location range of at least two segments set on the blood vessel wall 402.

[0089] Step 204: Determine the first vector velocity of blood flow in the longitudinal section of the blood vessel based on the first ultrasound echo data.

[0090] In one embodiment, the imaging processing module 110 can also acquire the first vector velocity of blood flow in the longitudinal section of the blood vessel 40 based on the first ultrasound echo data. Among them, the first vector velocity This includes the magnitude and direction of blood flow velocity. First vector velocity. This represents the actual velocity of blood flow, used to characterize the true direction and magnitude of blood flow within the blood vessel 40.

[0091] In this embodiment, the transmitting circuit 102 can excite the probe 100 to emit the first ultrasound wave towards the tissue containing blood vessels along at least two transmitting directions. The imaging processing module 110 can receive the first ultrasound echo returned by the tissue under test according to the receiving circuit 104 to obtain first ultrasound echo data along each of the at least two transmitting directions. Based on the first ultrasound echo data, the imaging processing module 110 obtains the velocity component of each point in the blood flow along each transmitting direction, and performs angle fitting on the obtained velocity components of each point in different transmitting directions to obtain the first vector velocity of each point in the blood flow in the blood vessel 40. The emission direction can refer to the angle between the direction of the ultrasonic beam and the normal of the probe 100 end face.

[0092] In one embodiment, the imaging processing module 110 may use a speckle tracking method to track the first ultrasound echo data to obtain the first vector velocity of blood flow in the longitudinal section of the blood vessel 40. Alternatively, the imaging processing module 110 determines the transverse and longitudinal velocities of the blood flow in the blood vessel 40 in the longitudinal section based on the first ultrasound echo data, and obtains the first vector velocity of the blood flow in the blood vessel in the longitudinal section based on the transverse and longitudinal velocities of the blood flow in the longitudinal section. Optionally, the longitudinal velocity can be obtained using traditional calculation methods based on the Doppler principle, or the transverse velocity can be obtained by generating a transversely oscillating ultrasonic field and then calculating it based on the autocorrelation method.

[0093] For example, the imaging processing module 110 can obtain at least two frames of image data based on the aforementioned first ultrasonic echo data, such as at least a first frame of image data and a second frame of image data, and select a tracking region in the first frame of image data. This tracking region may contain the target point whose velocity vector is to be obtained. For example, the tracking region may be a neighborhood of the target point or a data block containing the target point. Then, the imaging processing module 110 searches for a region corresponding to the tracking region in the second frame of image data, for example, searching for the region with the greatest similarity to the aforementioned tracking region as the tracking result region. Here, the similarity can be measured using methods commonly used in the art. The imaging processing module 110 can also obtain the first vector velocity of each target point based on the positions of the aforementioned tracking region and the aforementioned tracking result region, as well as the time interval between the first frame of image data and the second frame of image data. The magnitude of the first vector velocity can be obtained by dividing the distance between the tracking area and the tracking result area (i.e., the displacement of the target point within a preset time interval) by the distance between the tracking area and the tracking result area. The direction of the first vector velocity can be the direction of the line connecting the tracking area and the tracking result area, i.e., the direction of the target point's movement within the preset time interval.

[0094] In one embodiment, compared to the aforementioned embodiment based on at least two transmission directions, ultrasound echo data can be obtained through at least two receiving directions. For example, the imaging processing module 110 can receive the first ultrasound echo returned from the tissue under test along at least two receiving directions to obtain ultrasound echo data along each of the at least two receiving directions. Then, based on the ultrasound echo data from each of the at least two receiving directions, the imaging processing module 110 determines the velocity component of the blood flow in the blood vessel along each of the at least two receiving directions in the longitudinal section, and based on the velocity component of each of the at least two receiving directions, determines the first vector velocity of the blood flow in the blood vessel 40 in the longitudinal section.

[0095] Step 206: Determine the first wall shear stress or the first wall shear rate at the test location on the longitudinal section based on the first vector velocity.

[0096] In this embodiment, the imaging processing module 110 determines the first wall shear stress or the first wall shear rate based on the velocity component of the first vector velocity along the first tangential direction at the test location. The first tangential direction is located within the plane of the longitudinal section of the blood vessel 40 and is the tangential direction on the anterior or posterior wall of the blood vessel where the test location 400 is located. Figure 3 The direction of tangent a shown, or, as Figure 4 The direction of the tangent b shown.

[0097] For example, the imaging processing module 110 is used to calculate the wall shear stress (WSS) or wall shear rate (WSR) of the test location 400 based on the first vector velocity of multiple points (or target points) near the test location 400, so as to obtain the first wall shear stress or first wall shear rate of the test location on the longitudinal section. Figure 3 As shown, the imaging processing module 110 determines the direction of the tangent a relative to the vessel wall 402 at the test location 400. The direction of the tangent a is parallel to the anterior or posterior wall of the vessel wall 402 in the longitudinal section, and extracts the first vector velocity of multiple points near the test location 400. If the first vector velocity Parallel to the direction of the tangent a at the position to be measured (400), the imaging processing module 110 can determine the first vector velocity of multiple points. Obtain the first wall shear stress or first wall shear rate at the test location 400. For example... Figure 4 As shown, if the location to be measured 400 is located at the curved portion of the blood vessel wall 402, the imaging processing module 110 acquires the first vector velocity. The velocity component v in the first tangential direction (parallel to the tangent b at the position to be measured 400) is the first vector velocity. The blood flow velocity component along the tangent direction (such as the direction of tangent b) of the blood vessel wall at the location to be measured, 400.

[0098] The imaging processing module 110 can process the first vector velocity. The velocity gradient of the blood vessel wall is obtained by differentiating the velocity component v in the first tangential direction from the normal radius of the vessel wall at the test location 400. The first wall shear rate is then determined based on this velocity gradient, or the first wall shear stress is determined based on the velocity gradient and the blood viscosity coefficient. The formula for the first wall shear stress can be expressed as:

[0099]

[0100] Where τ represents the shear stress on the blood vessel wall, μ is the blood viscosity coefficient, v is the velocity component of the vector velocity along the tangent direction of the blood vessel wall at the position to be measured, which is the direction parallel to the blood vessel wall when the blood vessel wall is a straight line, wall represents the measurement position of WSS, i.e. the blood vessel wall; r is the position information of velocity v, which can also be expressed as the distance relative to the blood vessel wall or relative to the center of the blood vessel cross-section. It represents the velocity derivative of the instantaneous vector velocity of blood flow near the test location along the tangential direction of the vessel wall at that test location; express The corresponding distance derivative; This can be represented as the velocity gradient. Wherein, This represents the wall shear rate of the blood vessel wall.

[0101] In this embodiment, μ refers to the blood viscosity coefficient. Human blood is a non-Newtonian fluid, so theoretically, this blood viscosity coefficient should be a variable (a non-constant number). This value is not only related to parameters such as hematocrit and plasma viscosity, but also changes with velocity gradients, although sometimes this effect is very small. If only approximate calculations are needed, a specific constant can be directly used as the blood viscosity coefficient for WSS calculation. For example, when calculating carotid artery WSS, an average blood viscosity coefficient value can be used.

[0102] For example, 0.0035 Pa·s, or expressed in centipoise (cP), 0.0035 Pa·s = 3.5 cP. Of course, this value varies from person to person and will fluctuate due to factors such as age and gender. Even for the same person, this value will fluctuate depending on blood flow velocity. This value can also be measured using the falling ball method. In practical applications, the default value provided by the system can be used. If the default value is considered inaccurate, it can be adjusted by manually entering a new value, such as the user inputting a new human blood viscosity coefficient value through an input device.

[0103] Step 208: A second ultrasound wave is emitted to the tissue containing blood vessels through the ultrasound probe, and second ultrasound echo data is generated after receiving the second ultrasound echo returned by the tissue.

[0104] In this embodiment, to obtain the three-dimensional wall shear stress or three-dimensional wall shear rate of the test location 400, after determining the first wall shear stress or first wall shear rate in the longitudinal section of the blood vessel, the imaging processing module 110 can also determine the second wall shear stress or second wall shear rate of the test location 400 in the cross section, and determine the three-dimensional wall shear stress of the test location 400 based on the first wall shear stress and the second wall shear stress, or determine the three-dimensional wall shear rate of the test location 400 based on the first wall shear rate and the second wall shear rate.

[0105] To obtain the second wall shear stress or second wall shear rate within the cross-section of the measured location 400, the transmitting circuit 102 can transmit a second ultrasonic wave to the blood vessel 40 via an ultrasonic probe after receiving the excitation timing. In this embodiment, the user can move the probe 100 along the transverse axis of the blood vessel 40 to transmit the second ultrasonic wave to one or more locations along the transverse axis of the blood vessel 40.

[0106] After a certain delay, the ultrasound probe can receive a second ultrasound echo reflecting from the tissue under test, carrying information about the object being detected. The probe 100 can convert this second ultrasound echo into an electrical signal. The receiving circuit 104 receives the electrical signal generated by the probe 100 and sends the processed electrical signal (including but not limited to amplification, gain compensation, detection, noise filtering, and A / D conversion) to the beamforming module 106. The beamforming module 106 performs focusing delay, weighting, and channel summation on the electrical signal, and the signal processing module 108 performs related signal processing to generate the second ultrasound echo data.

[0107] Step 210: Obtain a cross-sectional ultrasound image of the blood vessel containing the location to be tested based on the second ultrasound echo data.

[0108] Please refer to the following: Figure 5The diagram shows a cross-sectional ultrasound image in one embodiment of this application. The imaging processing module 110 can generate a cross-sectional ultrasound image 510 based on the second ultrasound echo data. Since the second ultrasound wave is emitted along the transverse axis of the blood vessel 40, the second ultrasound echo data can include cross-sectional ultrasound images 510 at one or more locations. Figure 5 As shown, the cross-sectional ultrasound image 510 shows that the vessel wall 402 can be roughly circular. Therefore, the tangent direction at any point on the vessel wall 402 or at the location to be measured is within the range of 0 to 360 degrees.

[0109] Step 212: Determine the second vector velocity of blood flow in the blood vessel on the cross-section based on the second ultrasound echo data.

[0110] In this embodiment, the transmitting circuit 102 can excite the probe 100 to emit second ultrasound waves towards the tissue containing blood vessels along at least two transmitting directions. The imaging processing module 110 can receive the second ultrasound echo returned by the tissue under test according to the receiving circuit 104 to obtain second ultrasound echo data along each of the at least two transmitting directions. Based on the second ultrasound echo data, the imaging processing module 110 obtains the velocity components of each point in the blood flow along each transmitting direction, and performs angle fitting on the obtained velocity components of each point in different transmitting directions to obtain the second vector velocity of each point in the blood flow in the blood vessel 40.

[0111] In one embodiment, the imaging processing module 110 may employ a speckle tracking method to track the second ultrasound echo data in order to obtain the second vector velocity of blood flow in the blood vessel 40 on the cross-section. Alternatively, the imaging processing module 110 determines the transverse and longitudinal velocities of the blood flow in the blood vessel 40 on the cross-section based on the second ultrasound echo data, and obtains the second vector velocity of the blood flow in the blood vessel on the cross-section based on the transverse and longitudinal velocities of the blood flow on the cross-section. For details, please refer to the aforementioned content on obtaining the first vector velocity.

[0112] Step 214: Determine the second wall shear stress or second wall shear rate at the test location on the cross section based on the second vector velocity.

[0113] In this embodiment, the imaging processing module 110 determines the second wall shear stress or the second wall shear rate based on the velocity component of the second vector velocity along the second tangential direction at the test location. The second tangential direction lies within the plane containing the cross-section of the blood vessel and is the tangential direction along the circumference of the blood vessel wall at the test location. Figure 5 The direction of the tangent c in the middle.

[0114] In this embodiment, after obtaining the first wall shear stress or the first wall shear rate within the longitudinal section, the user can further adjust the position and direction of the ultrasonic waves emitted by the probe 100 to obtain the second wall shear stress or the second wall shear rate within the cross-section; or, after obtaining the second wall shear stress or the second wall shear rate within the cross-section, the user can further adjust the position and direction of the ultrasonic waves emitted by the probe 100 to obtain the first wall shear stress or the first wall shear rate within the longitudinal section. In one embodiment, the first wall shear stress or the first wall shear rate and the second wall shear stress or the second wall shear rate can be obtained at different times. For example, the first wall shear stress or the first wall shear rate can be obtained within a first preset time, and the second wall shear stress or the second wall shear rate can be obtained within a second preset time, where the first preset time is earlier than the second preset time. After obtaining the first wall shear stress or the first wall shear rate at the location to be measured, the user needs to move the probe 100 along the length of the blood vessel 40 to obtain the second wall shear stress or the second wall shear rate within the cross-section. Therefore, the imaging processing module 110 needs to determine the test location 400 on the cross-section of the blood vessel from the second ultrasound echo data. That is, it needs to obtain an ultrasound image containing the test location 400 from the cross-sectional ultrasound images 510 corresponding to multiple location points, and determine the second wall shear stress or second wall shear rate at the test location 400 based on the obtained ultrasound image.

[0115] When obtaining a cross-sectional ultrasound image of blood vessel 40, the user can obtain multiple frames of cross-sectional ultrasound images at different positions as the probe 100 moves along the transverse axis of blood vessel 40. Therefore, the imaging processing module 110 can obtain multiple frames of cross-sectional ultrasound images of blood vessel 40 based on the second ultrasound echo data, and also needs to include the cross-sectional ultrasound image of the blood vessel at the test position 400 from the multiple frames of cross-sectional ultrasound images.

[0116] Please refer to the following: Figure 6 The image shown is a schematic diagram illustrating the acquisition of the target location in a cross-sectional ultrasound image according to an embodiment of this application. For example, as... Figure 6 As shown in (a), in the longitudinal section ultrasound image 500, if the position to be measured 400 is point p, the imaging processing module 110 needs to acquire cross-sectional ultrasound images 510 at multiple locations along the length of the blood vessel 40. For example, the user can place the probe 100 at the first position 410, the second position 412, the third position 414, and the fourth position 416 to obtain the cross-sectional ultrasound image 510 at each position, and select the cross-sectional ultrasound image 510 containing the position to be measured 400 from the cross-sectional ultrasound images at the first position 410, the second position 412, the third position 414, and the fourth position 416.

[0117] In this embodiment, the blood vessels in the longitudinal section ultrasound image have first morphological information, and the blood vessels in the cross-sectional ultrasound images of different frames have second morphological information. The imaging processing module 110 can determine the first morphological information in the ultrasound image (such as the longitudinal section ultrasound image 500) of the location 400 to be tested at the longitudinal section, and determine the cross-sectional ultrasound image with the second morphological information corresponding to the first morphological information from multiple frames of cross-sectional ultrasound images as the cross-sectional ultrasound image of the blood vessel at the location 400 to be tested. The first morphological information may include one or more of the diameter of the blood vessel and the number of blood vessels, and the second morphological information may include one or more of the diameter of the blood vessel and the number of blood vessels.

[0118] In one embodiment, the imaging processing module 110 may determine, based on the first diameter of the location 400 in the longitudinal section ultrasound image 500, a cross-sectional ultrasound image having a second diameter corresponding to the first diameter from multiple cross-sectional ultrasound images as the cross-sectional ultrasound image of the blood vessel at the location 400 to be tested.

[0119] like Figure 6 As shown in (a), if the position to be tested 400 is located at position m, then the first morphological information of the position to be tested 400 in the longitudinal section ultrasound image 500 is determined as follows: the first diameter is e. Therefore, the imaging processing module 110 can select the ultrasound image with a blood vessel diameter of e from the cross-sectional ultrasound images 510 corresponding to the first position 410, the second position 412, the third position 414, and the fourth position 416. For example, the cross-sectional ultrasound image corresponding to the blood vessel 40 at the third position 414 is determined as the cross-sectional ultrasound image of the position to be tested 400. In one embodiment, the imaging processing module 110 will also calculate the first diameter at the position to be tested 400 and display the calculated first diameter; the imaging processing module 110 can also calculate the second diameter contained in each frame of cross-sectional ultrasound image. Furthermore, the imaging processing module 110 can select the cross-sectional ultrasound image containing the second diameter that is closest to or the same as the first diameter from multiple frames of cross-sectional ultrasound images as the cross-sectional ultrasound image of the position to be tested 400. Alternatively, the user can perform a selection operation based on the first diameter and the second diameter of the blood vessel in each cross-sectional ultrasound image, such as selecting the cross-sectional ultrasound image containing the second diameter that is closest to or the same as the first diameter from multiple frames of cross-sectional ultrasound images as the cross-sectional ultrasound image of the location to be tested 400.

[0120] In one embodiment, the user can adjust the current position of the probe 100 along the length direction of the blood vessel 40 based on the second diameter of the cross-sectional ultrasound image of the current frame and the first diameter of the position to be measured in the longitudinal section. For example, if the first diameter of the position to be measured (e.g., position m) in the longitudinal section ultrasound image is e, and based on the longitudinal section ultrasound image, it is known that position m is located between the second position 412 and the fourth position 416, and the first diameter of position m is also between the diameters of the second position 412 and the fourth position 416. Thus, if the second diameter of the current cross-sectional ultrasound image is smaller than the first diameter e, the user can control the probe 100 to move from the second position 412 to the fourth position 416 (e.g., from left to right), and can acquire the third position 414 (i.e., the cross-sectional ultrasound image corresponding to position m) during the movement. If the second diameter of the current cross-sectional ultrasound image is larger than the first diameter e, the user can control the probe 100 to move from the fourth position 416 to the second position 412 (e.g., from right to left), and can acquire the third position 414 (i.e., the cross-sectional ultrasound image corresponding to position m) during the movement.

[0121] In one embodiment, the imaging processing module 110 may also perform coarse screening of multiple cross-sectional ultrasound images based on the number of blood vessels at the location to be tested, in order to determine the cross-sectional ultrasound images containing the location to be tested.

[0122] For example, if the target location is at point p, and point p is the bifurcation point of blood vessel 40, then the imaging processing module 110 can determine that the first morphological information of the target location 400 in the longitudinal section ultrasound image 500 is: the number of blood vessels is 2. Therefore, the imaging processing module 110 can select the ultrasound image with a number of blood vessels of 2 from the cross-sectional ultrasound images 510 corresponding to the first location 410, the second location 412, the third location 414, and the fourth location 416, that is, from... Figure 6 (b) Figure 6 (c) Figure 6 (d) Figure 6 (e) As shown in the cross-sectional ultrasound image 510, the imaging processing module 110 can determine that the cross-sectional ultrasound image 510 corresponding to the first position 410 contains the position to be measured 400. Furthermore, the imaging processing module 110 can obtain the second wall shear stress or the second wall shear rate based on the second ultrasound echo data generated from the cross-sectional ultrasound image 510 at the first position 410. In one embodiment, if multiple cross-sectional ultrasound images exist with the same number of blood vessels as the position to be measured, the imaging processing module 110 further determines the blood vessel diameter at the position to be measured in the longitudinal cross-sectional ultrasound image and selects the cross-sectional ultrasound image with the same or closest blood vessel diameter from among the multiple cross-sectional ultrasound images with the same number of blood vessels.

[0123] In this embodiment, the imaging processing module 110 is used to determine the second vector velocity based on multiple points located near the test location 400. The wall shear stress at the test location 400 is calculated using the velocity component along the second tangential direction to obtain the second wall shear stress or the second wall shear rate. For example, the imaging processing module 110 can calculate the second vector velocity based on multiple points near the test location 400. The velocity component v in the direction parallel to the tangent c is used to obtain the second wall shear stress or the second wall shear rate. The formula for calculating the second wall shear stress or the second wall shear rate can be understood by referring to the formula used to calculate the first wall shear stress or the first wall shear rate mentioned above, and will not be repeated here.

[0124] Step 216: Determine the three-dimensional wall shear stress at the test location based on the first wall shear stress and the second wall shear stress, or determine the three-dimensional wall shear rate at the test location based on the first wall shear rate and the second wall shear rate.

[0125] For an example of synthesizing three-dimensional wall shear stress, please refer to [link / reference]. Figure 7 The diagram shows a schematic representation of the synthesis of three-dimensional wall shear stress in one embodiment of this application. After obtaining the first and second wall shear stresses, the imaging processing module 110 can obtain the three-dimensional wall shear stress at the target location 400 based on vector synthesis. The method for synthesizing the three-dimensional wall shear rate can be found in [reference needed]. Figure 7 The relevant explanations regarding the synthesis of three-dimensional wall shear stress are explained below. In this embodiment, since the first wall shear stress or the first wall shear rate is located within the longitudinal section, and the second wall shear stress or the second wall shear rate is located within the cross section, and the longitudinal section and the cross section at the same location on the vessel wall 402 are perpendicular or approximately perpendicular to each other, the direction of the first wall shear stress or the first wall shear rate is also perpendicular or approximately perpendicular to each other.

[0126] Because the heart beats periodically, the state information of any point on the vessel wall 402 is directly or indirectly related to the heartbeat. For example, when the heart beats periodically, the blood flow velocity within the vessel 40 changes constantly, and the wall shear stress or wall shear rate also changes over time. Therefore, the state information of any point on the vessel wall 402 also exhibits a periodic changing trend. Thus, when the imaging processing module 110 obtains the three-dimensional wall shear stress or three-dimensional wall shear rate at the target location 400, the corresponding state information of the first wall shear stress or first wall shear rate and the second wall shear stress or second wall shear rate should be the same or corresponding.

[0127] In this embodiment, the longitudinal section ultrasound image includes one or more ultrasound images of the test location at different times, and the cross section ultrasound image includes one or more ultrasound images of the test location. The imaging processing module 110 can obtain the wall shear stress or wall shear rate of each ultrasound image based on the aforementioned processing steps, such as obtaining each first wall shear stress or first wall shear rate in one or more longitudinal section ultrasound images, and obtaining each second wall shear stress or second wall shear rate in one or more cross section ultrasound images. After determining the first target wall shear stress of the longitudinal section ultrasound image of the first target frame at the location to be measured, the imaging processing module 110 can determine the second target wall shear stress of the cross-sectional ultrasound image of the second target frame corresponding to the first target wall shear stress of the longitudinal section ultrasound image of the first target frame based on the cardiac cycle or velocity curve of the location to be measured. Alternatively, it can determine the second target wall shear stress of the cross-sectional ultrasound image of the second target frame corresponding to the first target wall shear rate of the longitudinal section ultrasound image of the first target frame based on the cardiac cycle or velocity curve of the location to be measured. After determining the second target wall shear stress of the cross-sectional ultrasound image of the second target frame corresponding to the first target wall shear rate of the longitudinal section ultrasound image of the first target frame, the imaging processing module 110 can determine the three-dimensional wall shear stress of the location to be measured 400 based on the first target wall shear stress and the second target wall shear stress. Alternatively, it can determine the three-dimensional wall shear rate of the location to be measured 400 based on the first target wall shear rate and the second target wall shear rate.

[0128] Please refer to the following: Figure 8 and Figure 9 The figure shown is a schematic diagram of the velocity change curves of the measured position in the longitudinal section and the cross section, respectively, in one embodiment of this application.

[0129] For example, the first preset time includes the first velocity curve corresponding to one or more cardiac cycles at the location to be measured (e.g., Figure 8 As shown), the second preset time includes the second velocity curve (e.g., at the location to be measured) corresponding to one or more cardiac cycles. Figure 9As shown, a cardiac cycle includes several frames of velocity information, including but not limited to velocity values ​​and velocity change values. The imaging processing module 110 can determine whether the velocity information of the first target wall shear stress in a cardiac cycle corresponds to the velocity information of the second target wall shear stress in a cardiac cycle, or it can determine whether the velocity information of the first target wall shear rate in a cardiac cycle corresponds to the velocity information of the second target wall shear rate in a cardiac cycle. For example, if the velocity information corresponding to the first target wall shear stress or the first target wall shear rate is the location of the maximum velocity in a cardiac cycle of the first velocity curve (such as the location corresponding to 3.5 Pa), then the imaging processing module 110 can also obtain the second target wall shear stress or the second target wall shear rate corresponding to the location of the maximum velocity in a cardiac cycle of the second velocity curve (such as the location corresponding to 1.5 Pa).

[0130] In one embodiment, the velocity gradient can be a value that changes over time. The imaging processing module 110 can obtain the maximum, minimum, or average value of the first wall shear stress or the first wall shear rate within a cardiac cycle, and obtain the maximum, minimum, or average value of the second wall shear stress or the second wall shear rate within a cardiac cycle. Furthermore, the three-dimensional wall shear stress or three-dimensional wall shear rate synthesized by the imaging processing module 110 can be the maximum, minimum, or average value of the three-dimensional wall shear force or three-dimensional wall shear rate within a cardiac cycle.

[0131] Step 218: Display the three-dimensional wall shear stress or three-dimensional wall shear rate at the location to be measured.

[0132] Please refer to the following: Figure 10 The figure shown is a schematic diagram of three-dimensional wall shear stress or three-dimensional wall shear rate in one embodiment of this application.

[0133] The imaging processing module 110 can display a two-dimensional ultrasound image 500 of the longitudinal section of the blood vessel 40, including the location to be measured, within the display device 112, such as... Figure 10 As shown in (a), the marker information corresponding to the magnitude of the three-dimensional wall shear stress or the magnitude of the three-dimensional wall shear rate, or the direction of the three-dimensional wall shear stress or the direction of the three-dimensional wall shear rate is displayed at the test location of the blood vessel. The marker information has characteristic values. Different magnitudes of three-dimensional wall shear stress or three-dimensional wall shear rate have different characteristic values, and different directions of three-dimensional wall shear stress or three-dimensional wall shear rate have different characteristic values.

[0134] Since three-dimensional wall shear stress or three-dimensional wall shear rate includes both magnitude and direction, in order to display the magnitude and direction of three-dimensional wall shear stress or three-dimensional wall shear rate in a two-dimensional plane, the imaging processing module 110 can display the magnitude of the three-dimensional wall shear stress or three-dimensional wall shear rate in the first output image 520, such as... Figure 10 As shown in (b), the direction of the three-dimensional wall shear stress or the three-dimensional wall shear rate can be displayed in the second output image 530, such as... Figure 10 As shown in (c). The imaging processing module 110 can acquire the three-dimensional wall shear force or three-dimensional wall shear rate at each location point (such as each location point on the anterior and posterior walls of the vessel wall 402) or the location to be measured in the longitudinal section ultrasound image 500. Therefore, the imaging processing module 110 can display corresponding marking information (such as color) at each location point on the vessel wall 402 displayed in the first output image 520, that is, display the magnitude of the three-dimensional wall shear stress or three-dimensional wall shear rate at each location point through the marking information. The imaging processing module 110 can also display corresponding marking information (such as color) at each location point on the vessel wall 402 displayed in the second output image 530, that is, display the direction of the three-dimensional wall shear stress or three-dimensional wall shear rate at each location point through the marking information, wherein the direction of the three-dimensional wall shear stress or three-dimensional wall shear rate at each location point is within the range of 0 to 360 degrees. In this embodiment, colors have different feature values ​​(or pixel values, including but not limited to grayscale pixel values ​​and color pixel values). The magnitude of the three-dimensional wall shear stress or the three-dimensional wall shear rate is related to or corresponds to the pixel value of the color. The direction of the three-dimensional shear stress or the three-dimensional wall shear rate can also be related to or correspond to the pixel value of the color.

[0135] In one embodiment, the ultrasound imaging system 10 may only obtain the second wall shear stress or second wall shear rate at the test location within the cross-section, and display the second wall shear stress or second wall shear rate at the test location. When displaying the second wall shear stress or second wall shear rate, the ultrasound imaging system 10 may display the blood vessel included in the cross-sectional ultrasound image 510, and display the second wall shear stress or second wall shear rate at the test location on the approximately circular blood vessel wall, such as through corresponding marking information (e.g., color). In one embodiment, the ultrasound imaging system 10 may determine the second wall shear stress or second wall shear rate at each point along the circumference of the blood vessel wall within the cross-section, such as displaying information such as the magnitude and direction of the second wall shear stress or second wall shear rate at each point along the circumference of the blood vessel wall.

[0136] The aforementioned method for detecting wall shear stress acquires the first wall shear stress or first wall shear rate at the test location within the longitudinal section using an ultrasound probe, and also acquires the second wall shear stress or second wall shear rate at the test location within the cross section. The three-dimensional wall shear stress at the test location is obtained by combining the first and second wall shear stresses, or the three-dimensional wall shear rate at the test location is obtained by combining the first and second wall shear rates. By providing wall shear stress or wall shear rate in other dimensions, users can perform clinical assessments related to arteriosclerosis based on the magnitude and direction of the displayed three-dimensional wall shear stress or wall shear rate, thus improving the accuracy and repeatability of the detection.

[0137] Please see Figure 11 The diagram shows a flowchart of a method for detecting the wall shear parameters of a blood vessel in another embodiment of this application. The detection method may include the following steps:

[0138] Step 700: A first ultrasound wave is emitted to the tissue containing blood vessels through an ultrasound probe, and first ultrasound echo data is generated after receiving the first ultrasound echo returned by the tissue.

[0139] In this embodiment, step 700 performs a similar function to step 200 in the aforementioned embodiment, and can be referred to step 200 in the aforementioned embodiment for details.

[0140] Step 702: Obtain a longitudinal section ultrasound image of the blood vessel based on the first ultrasound echo data, and determine the location to be tested on the vessel wall of the blood vessel in the longitudinal section ultrasound image.

[0141] In this embodiment, step 702 performs a similar function to step 202 in the aforementioned embodiment, and can be referred to step 202 in the aforementioned embodiment for details.

[0142] Step 704: A second ultrasound wave is emitted to the tissue containing blood vessels through the ultrasound probe, and second ultrasound echo data is generated after receiving the second ultrasound echo returned by the tissue.

[0143] In this embodiment, step 704 performs a similar function to step 208 in the aforementioned embodiment, and can be referred to step 208 in the aforementioned embodiment for details.

[0144] Step 706: Obtain a cross-sectional ultrasound image of the blood vessel containing the location to be tested based on the second ultrasound echo data.

[0145] In this embodiment, step 706 performs a similar function to step 210 in the aforementioned embodiment, and can be referred to step 210 in the aforementioned embodiment for details.

[0146] Step 708: A third ultrasound wave is emitted through the ultrasound probe toward the tissue containing blood vessels, and third ultrasound echo data is generated after receiving the third ultrasound echo returned by the tissue.

[0147] Step 710: Determine the first vector velocity of blood flow in the longitudinal section of the blood vessel based on the third ultrasound echo data.

[0148] Compared to the aforementioned embodiments, this embodiment can acquire the first vector velocity of blood flow in the longitudinal section of the blood vessel 40 based on the emission of a new ultrasonic wave. For example, a third ultrasonic wave is emitted to the test tissue containing the blood vessel through an ultrasonic probe, and after receiving the third ultrasonic echo returned by the test tissue, third ultrasonic echo data is generated, and the first vector velocity is acquired based on the third ultrasonic echo data. For example, a third ultrasonic wave is emitted to the test tissue containing the blood vessel through an ultrasonic probe along at least two emission directions, and the imaging processing module 110 can be used to receive the third ultrasonic echo returned by the test tissue to obtain third ultrasonic echo data along each of the at least two emission directions; the imaging processing module 110 acquires the velocity component of blood flow in the blood vessel along each of the at least two emission directions based on the third ultrasonic echo data; the imaging processing module 110 can also determine the first vector velocity based on the velocity component of blood flow in the blood vessel along each of the at least two emission directions. In one embodiment, the imaging processing module 110 may use a speckle tracking method to track the third ultrasound echo data to obtain the first vector velocity of blood flow in the longitudinal section of the blood vessel; or, the imaging processing module 110 may determine the transverse and longitudinal velocities of blood flow in the longitudinal section of the blood vessel based on the third ultrasound echo data, and obtain the first vector velocity of blood flow in the longitudinal section of the blood vessel based on the transverse and longitudinal velocities of blood flow in the longitudinal section. Alternatively, the imaging processing module 110 may receive the third ultrasound echo returned from the tissue under test along at least two receiving directions via the receiving circuit 104 to obtain ultrasound echo data along each of the at least two receiving directions; the imaging processing module 110 may also determine the velocity component of blood flow in the longitudinal section along each of the at least two receiving directions based on the ultrasound echo data in each of the at least two receiving directions, and determine the first vector velocity based on the velocity component of each of the at least two receiving directions.

[0149] Step 712: Determine the first wall shear stress or the first wall shear rate at the test location on the longitudinal section based on the first vector velocity.

[0150] In this embodiment, step 712 performs a similar function to step 206 in the aforementioned embodiment, and can be referred to step 206 in the aforementioned embodiment for details.

[0151] Step 714: A fourth ultrasound wave is emitted through the ultrasound probe toward the tissue containing blood vessels, and fourth ultrasound echo data is generated after receiving the fourth ultrasound echo returned by the tissue.

[0152] Step 716: Determine the second vector velocity of blood flow in the blood vessel on the cross-section based on the fourth ultrasound echo data.

[0153] Compared to the aforementioned embodiments, this embodiment can acquire the second vector velocity of blood flow in the cross-section of the blood vessel 40 based on the emission of new ultrasound waves. For example, a fourth ultrasound wave is emitted to the test tissue containing the blood vessel through an ultrasound probe, and after receiving the fourth ultrasound echo returned by the test tissue, fourth ultrasound echo data is generated, and the second vector velocity is acquired based on the fourth ultrasound echo data. For example, a fourth ultrasound wave is emitted to the test tissue containing the blood vessel through an ultrasound probe along at least two emission directions, and the imaging processing module 110 can be used to receive the fourth ultrasound echo returned by the test tissue to obtain fourth ultrasound echo data along each of the at least two emission directions; the imaging processing module 110 acquires the velocity component of blood flow in the blood vessel along each of the at least two emission directions based on the fourth ultrasound echo data; the imaging processing module 110 can also determine the second vector velocity based on the velocity component of blood flow in the blood vessel along each of the at least two emission directions. In one embodiment, the imaging processing module 110 may use a speckle tracking method to track the fourth ultrasound echo data to obtain a second vector velocity of blood flow in the blood vessel on a cross-section; or, the imaging processing module 110 may determine the transverse and longitudinal velocities of blood flow in the blood vessel on a cross-section based on the fourth ultrasound echo data, and obtain a first vector velocity of blood flow in the blood vessel on a cross-section based on the transverse and longitudinal velocities of blood flow on a cross-section. Alternatively, the imaging processing module 110 may receive the fourth ultrasound echo returned from the tissue under test along at least two receiving directions via the receiving circuit 104 to obtain ultrasound echo data along each of the at least two receiving directions; the imaging processing module 110 may also determine the velocity component of blood flow in the blood vessel on a cross-section along each of the at least two receiving directions based on the ultrasound echo data in each of the at least two receiving directions, and determine the second vector velocity based on the velocity component of each of the at least two receiving directions.

[0154] Step 718: Determine the second wall shear stress or second wall shear rate at the test location on the cross section based on the second vector velocity.

[0155] In this embodiment, step 718 performs a similar function to step 214 in the aforementioned embodiment, and can be referred to step 214 in the aforementioned embodiment for details.

[0156] Step 720: Determine the three-dimensional wall shear stress at the test location based on the first wall shear stress and the second wall shear stress, or determine the three-dimensional wall shear rate at the test location based on the first wall shear rate and the second wall shear rate.

[0157] In this embodiment, step 720 performs a similar function to step 216 in the aforementioned embodiment, and can be referred to step 216 in the aforementioned embodiment for details.

[0158] Step 722: Display the three-dimensional wall shear stress or three-dimensional wall shear rate at the location to be measured.

[0159] In this embodiment, step 722 performs a similar function to step 218 in the aforementioned embodiment, and can be referred to step 218 in the aforementioned embodiment for details.

[0160] In one embodiment, steps 708 to 712 can be adjusted to occur after step 702. In this way, after obtaining a longitudinal section ultrasound image using the first ultrasound echo data, the user can emit a third ultrasound wave through the probe to obtain a first vector velocity based on the corresponding third ultrasound echo data. Subsequently, the user can adjust the emission direction of the probe 100 to emit the second ultrasound wave and then the subsequent fourth ultrasound wave.

[0161] The above-mentioned method for detecting wall shear parameters uses an ultrasound probe to emit different ultrasound waves to obtain longitudinal section ultrasound images, cross section ultrasound images, first vector velocity, and second vector velocity. This eliminates the need for users to repeatedly change or adjust the probe's emission method relative to the blood vessel, thus providing certain operational convenience.

[0162] Please see Figure 12 The diagram shows a flowchart of a method for detecting the wall shear parameters of a blood vessel in another embodiment of this application. The detection method may include the following steps:

[0163] In this embodiment, the probe 100 can be a planar array probe, that is, the ultrasound imaging system 10 can obtain the three-dimensional wall shear stress or three-dimensional wall shear rate at any point on the vessel wall 402 of the blood vessel 40 through the planar array probe.

[0164] Step 900: A first ultrasound wave is emitted to the tissue under test containing blood vessels through an area array probe, and first ultrasound echo data is generated after receiving the first ultrasound echo returned by the tissue under test.

[0165] The probe 100 typically comprises an array of multiple elements. During each ultrasonic wave transmission, all or a portion of the elements of the probe 100 participate in the transmission. Each element or portion of these elements is excited by the transmission pulse and transmits an ultrasonic wave. The ultrasonic waves emitted by these elements superimpose during propagation, forming a composite ultrasonic beam that is transmitted to the scanning target. The direction of this composite ultrasonic beam is the ultrasonic propagation direction mentioned in this paper.

[0166] In this embodiment, the transmitting circuit 102 excites the probe 100 to emit an ultrasonic beam toward the tissue under test. Different ultrasonic propagation directions are obtained by controlling the sound beam and dynamically focusing the probe by changing the delay time of each array element in the probe 100. After a certain delay, the probe 100 receives the ultrasonic echo reflecting back from the tissue under test, carrying information about the object being detected. The probe 100 converts this ultrasonic echo into an electrical signal. The receiving circuit 104 receives the electrical signal generated by the probe 100 and sends the processed electrical signal (including but not limited to amplification, gain compensation, detection, noise filtering, and A / D conversion) to the beamforming module 106. The beamforming module 106 performs focusing delay, weighting, and channel summation on the electrical signal, and the signal processing module 108 performs related signal processing to generate ultrasonic echo data.

[0167] Step 902: Based on the ultrasound echo data, acquire a three-dimensional ultrasound image of the blood vessel and determine the location to be tested on the vessel wall in the three-dimensional ultrasound image.

[0168] The imaging processing module 110 can generate a three-dimensional ultrasound image based on ultrasound echo data, and can display the three-dimensional ultrasound image through the display device 112. The three-dimensional ultrasound image contains the three-dimensional spatial information of each location point, such as the three-dimensional coordinate value of each location point in a three-dimensional spatial coordinate system. When displaying the three-dimensional ultrasound image, the user can select a location point on the blood vessel wall as the location to be measured in the three-dimensional ultrasound image. In other embodiments, the imaging processing module 110 can automatically acquire the blood vessel wall of the three-dimensional ultrasound image and determine a location point on the blood vessel wall or a location point in a region as the location to be measured.

[0169] Step 904: Determine the three-dimensional vector velocity of blood flow in the blood vessel based on the first ultrasound echo data.

[0170] An ultrasonic beam can be emitted towards the tissue under test along multiple emission directions (e.g., at least three directions) using an area array probe to generate multiple sets of ultrasonic echo data corresponding to these emission directions. Based on these multiple sets of ultrasonic echo data, the velocity components of each location point within the tissue under test in the multiple emission directions can be calculated. Thus, the imaging processing module 110 can calculate (e.g., through angle fitting) the three-dimensional vector velocity at the corresponding location point based on the velocity components of each location point within the tissue under test in the multiple emission directions. Alternatively, the three-dimensional vector velocity at the corresponding location point can be obtained by performing angle fitting based on the velocity components obtained in multiple receiving directions. For a related explanation of obtaining vector velocity through multi-angle fitting, please refer to the aforementioned synthesis of vector velocities; it will not be repeated here.

[0171] In one embodiment, a new ultrasonic wave (such as a second ultrasonic wave) can be emitted by an area array probe, and second ultrasonic echo data can be generated after receiving the second ultrasonic echo returned by the tissue under test; the imaging processing module 110 can determine the three-dimensional vector velocity of blood flow in the blood vessel based on the second ultrasonic echo data.

[0172] Step 906: Determine the three-dimensional wall shear stress or three-dimensional wall shear rate at the location to be measured based on the three-dimensional vector velocity.

[0173] In this embodiment, the imaging processing module 110 can determine a first plane tangent to the position to be measured, and determine the velocity component of the three-dimensional vector velocity in the projection direction of the first plane; the imaging processing module 110 also determines the three-dimensional wall shear stress or three-dimensional wall shear rate at the position to be measured based on the velocity component of the three-dimensional vector velocity in the projection direction of the first plane, wherein the three-dimensional wall shear stress at the position to be measured... The calculation formula is as follows:

[0174]

[0175] in, It is three-dimensional wall shear stress. This represents the three-dimensional wall shear rate, where μ is the blood viscosity coefficient. It is the normal vector pointing into the blood vessel at the location to be measured. · represents the dot product (also called the dot product or inner product), and × represents the cross product (also called the cross product or outer product). The strain tensor can be expressed as:

[0176]

[0177] Step 908: Display the three-dimensional wall shear stress or three-dimensional wall shear rate at the location to be measured.

[0178] Please refer to the following example, which focuses on three-dimensional wall shear stress. Figure 13The figure shown is a schematic diagram of three-dimensional wall shear stress in another embodiment of this application.

[0179] While displaying a three-dimensional structural schematic diagram of the blood vessel 40 on the display device 112, the imaging processing module 110 displays marking information of three-dimensional wall shear stress at the corresponding test location. It also controls the display of marking information with corresponding three-dimensional wall shear stress magnitude or direction at the test location of the blood vessel. The marking information has characteristic values; different three-dimensional wall shear stress magnitudes have different characteristic values, and different three-dimensional wall shear stress directions have different characteristic values. Since the three-dimensional wall shear stress includes both magnitude and direction, the imaging processing module 110 displays the magnitude and direction of the three-dimensional wall shear stress at various points on the blood vessel wall (e.g., displaying various points within a three-dimensional blood vessel wall of a preset length) through different output images. Figure 13 (a) is the output image of the three-dimensional wall shear stress magnitude. Figure 13 (b) is the output image of the three-dimensional wall shear stress direction. Different sizes and directions can be distinguished by different colors. The vessel wall can be a cylindrical surface or an irregular curved surface. The display method of the three-dimensional wall shear rate can also be found in [reference needed]. Figure 13 Please refer to the relevant explanations for further details; they will not be repeated here.

[0180] The aforementioned method for detecting three-dimensional wall shear parameters acquires the three-dimensional surface shear stress or three-dimensional wall shear rate at various locations on the blood vessel using an area array probe. The display device then shows the marking information of the corresponding three-dimensional surface shear stress or three-dimensional wall shear rate at each location on the blood vessel wall. In this way, users can perform clinical assessments related to arteriosclerosis by observing the magnitude and direction of the displayed three-dimensional wall shear stress or three-dimensional wall shear rate, thereby improving the accuracy and repeatability of the detection.

[0181] Please see Figure 14 The diagram shown is a block diagram of an ultrasound imaging system according to another embodiment of this application. Figure 13 As shown, the ultrasound imaging system 80 can be applied to the above embodiments. The ultrasound imaging system 80 provided in this application will be described below. The ultrasound imaging system 80 may include a processor 800, a memory 802, a probe 100, a control circuit 804, and a display device 112, as well as a computer program (instructions) stored in the memory 802 and executable on the processor 800. The ultrasound imaging system 80 may also include other hardware components, such as communication devices, buttons, keyboards, etc., which will not be elaborated here. The processor 800 can exchange data with the probe 100, the control circuit 804, the memory 802, and the display device 112 via signal line 808.

[0182] The processor 800 can be a Central Processing Unit (CPU), or other general-purpose processors, digital signal processors (DSPs), application-specific integrated circuits (ASICs), field-programmable gate arrays (FPGAs), or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, etc. The general-purpose processor can be a microprocessor or any conventional processor. The processor is the control center of the ultrasound imaging system 80, connecting various parts of the ultrasound imaging system 80 via various interfaces and lines. In this embodiment, the processor 800 can be used to generate excitation timing to control the probe 100 to emit ultrasonic waves, and can be used to implement all the functions of the imaging processing module 110. It can also integrate the functions of the beamforming module 106 and the signal processing module 108, as detailed in the foregoing embodiments.

[0183] The control circuit 804 may include the functions of the transmitting circuit 102, receiving circuit 104, beamforming module 106 and / or signal processing module 108 in the above embodiments, and can be referred to the foregoing embodiments for details.

[0184] The memory 802 can be used to store the computer program and / or modules. The processor 800 implements various functions of the above-mentioned detection method by running or executing the computer program and / or modules stored in the memory 802 and calling the data stored in the memory 802. The memory 802 may mainly include a program storage area and a data storage area. The program storage area may store the operating system, at least one application program required for a function, etc. In addition, the memory 802 may include high-speed random access memory, and may also include non-volatile memory, such as hard disk, memory, plug-in hard disk, smart media card (SMC), secure digital (SD) card, flash card, at least one disk storage device, flash memory device, or other volatile solid-state storage device.

[0185] The display device 112 can display a user interface (UI), a graphical user interface (GUI), or a two-dimensional or three-dimensional image of the tissue being tested. The ultrasound imaging system 80 can also be used as an input device and an output device. The display device 112 may include at least one of liquid crystal display (LCD), thin film transistor LCD (TFT-LCD), organic light-emitting diode (OLED) touch display, flexible touch display, three-dimensional (3D) touch display, etc.

[0186] The processor 800 reads the executable program code stored in the memory 802 to run a program corresponding to the executable program code, so as to execute the detection method in any of the preceding embodiments.

[0187] In the above embodiments, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions in other embodiments.

[0188] In the several embodiments provided in this application, it should be understood that the disclosed apparatus can be implemented in other ways. For example, the apparatus embodiments described above are merely illustrative; for instance, the division of modules is only a logical functional division, and in actual implementation, there may be other division methods. For example, multiple modules or components may be combined or integrated into another system, or some features may be ignored or not executed. Furthermore, the coupling or direct coupling or communication connection shown or discussed may be an indirect coupling or communication connection between devices or units through some interfaces, and may be electrical or other forms.

[0189] In the various embodiments of this application, the functional units can be integrated into one processing unit, or each unit can exist physically separately, or two or more units can be integrated into one unit. The integrated unit can be implemented in hardware or as a software functional unit.

[0190] If the integrated unit is implemented as a software functional unit and sold or used as an independent product, it can be stored in a computer-readable storage device. Based on this understanding, the technical solution of this application, in essence, or the part that contributes to the prior art, or all or part of the technical solution, can be embodied in the form of a software product. This computer software product is stored in a memory and includes several instructions to cause a computer device (which may be a personal computer, server, or network device, etc.) to execute all or part of the steps of the methods described in the various embodiments of this application.

[0191] The embodiments of this application have been described in detail above. Specific examples have been used to illustrate the principles and implementation methods of this application. The description of the above embodiments is only for the purpose of helping to understand the method and core ideas of this application. At the same time, for those skilled in the art, there will be changes in the specific implementation methods and application scope based on the ideas of this application. Therefore, the content of this specification should not be construed as a limitation of this application.

Claims

1. A method for detecting shear parameters of blood vessel walls, characterized in that, The method includes: The first ultrasound wave is emitted into the tissue containing blood vessels by an ultrasound probe, and the first ultrasound echo data is generated after receiving the first ultrasound echo returned by the tissue. Based on the first ultrasound echo data, a longitudinal section ultrasound image of the blood vessel is obtained, and the test location on the vessel wall of the blood vessel in the longitudinal section ultrasound image is determined. The ultrasound probe emits a third ultrasound wave into the tissue containing blood vessels and generates third ultrasound echo data after receiving the third ultrasound echo returned by the tissue. The first vector velocity of blood flow in the blood vessel in the longitudinal section is determined based on the third ultrasound echo data. The first wall shear stress or first wall shear rate at the test location on the longitudinal section is determined based on the first vector velocity. The ultrasound probe emits a second ultrasound wave to the tissue containing blood vessels and generates second ultrasound echo data after receiving the second ultrasound echo returned by the tissue. A cross-sectional ultrasound image of the blood vessel containing the location to be tested is obtained based on the second ultrasound echo data. The ultrasound probe emits a fourth ultrasound wave into the tissue containing blood vessels and generates fourth ultrasound echo data after receiving the fourth ultrasound echo returned by the tissue. The second vector velocity of blood flow in the blood vessel on the cross-section is determined based on the fourth ultrasound echo data. The second wall shear stress or second wall shear rate at the measured location on the cross section is determined based on the second vector velocity. The three-dimensional wall shear stress at the test location is determined based on the first wall shear stress and the second wall shear stress, or the three-dimensional wall shear rate at the test location is determined based on the first wall shear rate and the second wall shear rate. This displays the three-dimensional wall shear stress or three-dimensional wall shear rate at the location to be measured.

2. A method for detecting shear parameters of the blood vessel wall, characterized in that, The method includes: The first ultrasound wave is emitted into the tissue containing blood vessels by an ultrasound probe, and the first ultrasound echo data is generated after receiving the first ultrasound echo returned by the tissue. Based on the first ultrasound echo data, a longitudinal section ultrasound image of the blood vessel is obtained, and the test location on the vessel wall of the blood vessel in the longitudinal section ultrasound image is determined. The first vector velocity of blood flow in the blood vessel in the longitudinal section is determined based on the first ultrasound echo data. The first wall shear stress or first wall shear rate at the test location on the longitudinal section is determined based on the first vector velocity. The ultrasound probe emits a second ultrasound wave to the tissue containing blood vessels and generates second ultrasound echo data after receiving the second ultrasound echo returned by the tissue. A cross-sectional ultrasound image of the blood vessel containing the location to be tested is obtained based on the second ultrasound echo data. The second vector velocity of blood flow in the blood vessel on the cross-section is determined based on the second ultrasound echo data. The second wall shear stress or second wall shear rate at the measured location on the cross section is determined based on the second vector velocity. The three-dimensional wall shear stress at the test location is determined based on the first wall shear stress and the second wall shear stress, or the three-dimensional wall shear rate at the test location is determined based on the first wall shear rate and the second wall shear rate. This displays the three-dimensional wall shear stress or three-dimensional wall shear rate at the location to be measured.

3. The detection method as described in claim 1 or 2, characterized in that, The step of determining the first wall shear stress or first wall shear rate at the test location on the longitudinal section based on the first vector velocity includes: The first wall shear stress or the first wall shear rate is determined based on the velocity component of the first vector velocity along the first tangential direction at the test location, wherein the first tangential direction is located in the plane of the longitudinal section of the blood vessel and is the tangential direction on the anterior or posterior wall of the blood vessel at the test location. The step of determining the second wall shear stress or second wall shear rate at the test location on the cross-section based on the second vector velocity includes: The second wall shear stress or the second wall shear rate is determined based on the velocity component of the second vector velocity along the second tangential direction at the test location, wherein the second tangential direction is located in the plane containing the cross-section of the blood vessel and is the tangential direction on the perimeter of the blood vessel wall at the test location.

4. The detection method as described in claim 1, characterized in that, The process of emitting a third ultrasound wave through the ultrasound probe to the tissue containing blood vessels, and generating third ultrasound echo data after receiving the third ultrasound echo returned by the tissue, includes: The ultrasound probe emits a third ultrasound wave into the tissue containing blood vessels along at least two emission directions and receives the third ultrasound echo returned by the tissue to obtain the third ultrasound echo data along each of the at least two emission directions. The determination of the first vector velocity of blood flow in the blood vessel in the longitudinal section based on the third ultrasound echo data includes: Based on the third ultrasound echo data, the velocity component of the blood flow in the blood vessel along each of the at least two emission directions is obtained; Based on the velocity component of the blood flow in the blood vessel along each of the at least two emission directions, determine the first vector velocity of the blood flow in the blood vessel on the longitudinal section; The process of emitting a fourth ultrasound wave through the ultrasound probe to the tissue containing blood vessels, and generating fourth ultrasound echo data after receiving the fourth ultrasound echo returned by the tissue, includes: The ultrasound probe emits a fourth ultrasound wave into the tissue containing blood vessels along at least two emission directions and receives the fourth ultrasound echo returned by the tissue to obtain the fourth ultrasound echo data along each of the at least two emission directions. The determination of the second vector velocity of blood flow in the blood vessel on the cross-section based on the fourth ultrasound echo data includes: Based on the fourth ultrasound echo data, the velocity component of the blood flow in the blood vessel along each of the at least two emission directions is obtained; The second vector velocity of the blood flow in the blood vessel on the cross section is determined based on the velocity component of the blood flow in the blood vessel along each of the at least two emission directions.

5. The detection method as described in claim 1, characterized in that, The determination of the first vector velocity of blood flow in the blood vessel in the longitudinal section based on the third ultrasound echo data includes: The third ultrasound echo data is tracked using a speckle tracking method to obtain the first vector velocity of blood flow in the blood vessel on the longitudinal section; or... Based on the third ultrasound echo data, the transverse velocity and longitudinal velocity of the blood flow in the blood vessel on the longitudinal section are determined, and based on the transverse velocity and longitudinal velocity of the blood flow on the longitudinal section, the first vector velocity of the blood flow in the blood vessel on the longitudinal section is obtained. The determination of the second vector velocity of blood flow in the blood vessel on the cross-section based on the fourth ultrasound echo data includes: The fourth ultrasound echo data is tracked using a speckle tracking method to obtain the second vector velocity of blood flow in the blood vessel on a cross-section; or, Based on the fourth ultrasound echo data, the transverse and longitudinal velocities of the blood flow in the blood vessel on the cross-section are determined, and based on the transverse and longitudinal velocities of the blood flow on the cross-section, the second vector velocity of the blood flow in the blood vessel on the cross-section is obtained.

6. The detection method as described in claim 1, characterized in that, The step of generating third ultrasound echo data after receiving the third ultrasound echo returned by the tested tissue includes: A third ultrasound echo returned from the tissue under test is received along at least two receiving directions to obtain ultrasound echo data along each of the at least two receiving directions. The determination of the first vector velocity of blood flow in the blood vessel in the longitudinal section based on the third ultrasound echo data includes: Based on the ultrasound echo data from each of the at least two receiving directions, determine the velocity components of the blood flow in the blood vessel along each of the at least two receiving directions in the longitudinal section; Based on the velocity component of each of the at least two receiving directions, the first vector velocity of the blood flow in the blood vessel on the longitudinal section is determined. The step of generating fourth ultrasound echo data after receiving the fourth ultrasound echo returned by the tested tissue includes: A fourth ultrasound echo returned from the tissue under test is received along at least two receiving directions to obtain ultrasound echo data along each of the at least two receiving directions. The determination of the second vector velocity of blood flow in the blood vessel on the cross-section based on the fourth ultrasound echo data includes: Based on the ultrasound echo data from each of the at least two receiving directions, determine the velocity component of the blood flow in the blood vessel along each of the at least two receiving directions in the cross-section; Based on the velocity component of each of the at least two receiving directions, a second vector velocity of the blood flow in the blood vessel on the cross-section is determined.

7. The detection method as described in claim 2, characterized in that, The step of generating first ultrasound echo data after receiving the first ultrasound echo returned by the tested tissue includes: First ultrasound echoes returned from the tissue under test are received along at least two receiving directions to obtain ultrasound echo data along each of the at least two receiving directions; The step of determining the first vector velocity of blood flow in the blood vessel in the longitudinal section based on the first ultrasound echo data includes: Based on the ultrasound echo data from each of the at least two receiving directions, determine the velocity components of the blood flow in the blood vessel along each of the at least two receiving directions in the longitudinal section; Based on the velocity component of each of the at least two receiving directions, the first vector velocity of the blood flow in the blood vessel on the longitudinal section is determined. The step of generating second ultrasound echo data after receiving the second ultrasound echo returned by the tested tissue includes: Second ultrasound echoes returned from the tissue under test are received along at least two receiving directions to obtain ultrasound echo data along each of the at least two receiving directions; The determination of the second vector velocity of blood flow in the blood vessel on the cross-section based on the second ultrasound echo data includes: Based on the ultrasound echo data from each of the at least two receiving directions, determine the velocity component of the blood flow in the blood vessel along each of the at least two receiving directions in the cross-section; Based on the velocity component of each of the at least two receiving directions, a second vector velocity of the blood flow in the blood vessel on the cross-section is determined.

8. The detection method as described in claim 1 or 2, characterized in that, The longitudinal section ultrasound image includes one or more ultrasound images of the location to be measured, and the cross section ultrasound image includes one or more ultrasound images of the location to be measured. The step of determining the three-dimensional wall shear stress at the test location based on the first wall shear stress and the second wall shear stress includes: Obtain the first target wall shear stress in the first target frame ultrasound image of the longitudinal section ultrasound image; Based on the cardiac cycle or velocity curve at the location to be tested, determine the second target wall shear stress of the second target frame ultrasound image corresponding to the first target wall shear stress of the first target frame ultrasound image in the cross-sectional ultrasound image; The three-dimensional wall shear stress at the test location is determined based on the first target wall shear stress and the second target wall shear stress. The step of determining the three-dimensional wall shear rate at the test location based on the first wall shear rate and the second wall shear rate includes: Obtain the first target wall shear rate of the first target frame ultrasound image in the longitudinal section ultrasound image; Based on the cardiac cycle or velocity curve at the location to be tested, determine the second target wall shear rate of the second target frame ultrasound image in the cross-sectional ultrasound image, which corresponds to the first target wall shear rate of the first target frame ultrasound image. The three-dimensional wall shear rate at the test location is determined based on the first target wall shear rate and the second target wall shear rate.

9. The detection method as described in claim 1 or 2, characterized in that, The step of obtaining a cross-sectional ultrasound image of the blood vessel at the location to be tested based on the second ultrasound echo data includes: Based on the second ultrasound echo data, multi-frame cross-sectional ultrasound images of the blood vessel are obtained. A cross-sectional ultrasound image containing the location to be tested is determined from multiple frames of cross-sectional ultrasound images of the blood vessel.

10. The detection method as described in claim 9, characterized in that, The blood vessels in the longitudinal section ultrasound image have first morphological information, and the blood vessels in different frames of cross-sectional ultrasound images have second morphological information. Determining the cross-sectional ultrasound image containing the blood vessel at the location to be tested from multiple frames of cross-sectional ultrasound images of the blood vessel includes: Obtain the first morphological information of the location to be measured in the longitudinal section ultrasound image; The cross-sectional ultrasound image with second morphological information corresponding to the first morphological information is determined from the multi-frame cross-sectional ultrasound images as the cross-sectional ultrasound image of the blood vessel at the location to be tested.

11. The detection method as described in claim 10, characterized in that, The first morphological information includes the diameter of the blood vessel, the second morphological information includes the diameter of the blood vessel, and the step of obtaining the first morphological information of the location to be measured in the longitudinal section ultrasound image includes: Obtain the first diameter of the blood vessel at the location to be tested; The step of determining the cross-sectional ultrasound image with second morphological information corresponding to the first morphological information from the multi-frame cross-sectional ultrasound images as the cross-sectional ultrasound image of the blood vessel at the location to be tested includes: From the multiple frames of cross-sectional ultrasound images, a frame of cross-sectional ultrasound image with a second diameter corresponding to the first diameter is determined as the cross-sectional ultrasound image of the blood vessel at the location to be tested.

12. The detection method as described in claim 11, characterized in that, The first morphological information also includes the number of blood vessels, and the second morphological information also includes the number of blood vessels. Before obtaining the first diameter of the blood vessels at the location to be tested, the method further includes: Obtain the first number of blood vessels at the location to be tested; Based on the first number of blood vessels, the multi-frame cross-sectional ultrasound images are coarsely screened to determine one or more target cross-sectional ultrasound images with the same number of blood vessels as the first. The step of determining a single cross-sectional ultrasound image with a second diameter corresponding to the first diameter from the multiple cross-sectional ultrasound images as the cross-sectional ultrasound image of the blood vessel at the location to be tested includes: From the one or more frames of target cross-sectional ultrasound images, determine a frame of cross-sectional ultrasound image with a second diameter corresponding to the first diameter as the cross-sectional ultrasound image of the blood vessel at the location to be tested.

13. The detection method as described in claim 1 or 2, characterized in that, The three-dimensional wall shear stress at the test location includes the magnitude and direction of the wall shear stress, and the three-dimensional wall shear rate at the test location includes the magnitude and direction of the wall shear rate. The three-dimensional wall shear stress at the test location of the blood vessel wall includes: Displaying a longitudinal cross-sectional ultrasound image of the blood vessel; The system controls multiple test locations of the blood vessel to display marking information corresponding to the magnitude or direction of three-dimensional wall shear stress. The marking information has characteristic values, with different three-dimensional wall shear stress magnitudes having different characteristic values ​​and different three-dimensional wall shear stress directions having different characteristic values. The three-dimensional wall shear rate displayed at the test location of the blood vessel wall includes: Displaying a longitudinal cross-sectional ultrasound image of the blood vessel; The system controls multiple test locations on the blood vessel to display marker information corresponding to the magnitude or direction of the three-dimensional wall shear rate. The marker information has feature values, with different feature values ​​for different three-dimensional wall shear rate magnitudes and different feature values ​​for different three-dimensional wall shear rate directions.

14. An ultrasound imaging system, characterized in that, The ultrasound imaging system includes: probe; A transmitting circuit that excites the probe to emit ultrasound waves from the tissue under test, which contains blood vessels; A receiving circuit controls the probe to receive ultrasound echoes returned from the tissue under test to obtain ultrasound echo data; A processor is configured to acquire the ultrasonic echo data, and when the processor executes a computer program stored in a memory, it is configured to implement the detection method as described in any one of claims 1 to 13.

15. A computer-readable storage medium storing computer instructions, characterized in that, When the computer instructions are executed by the processor, they implement the detection method as described in any one of claims 1 to 13.

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