An OCT detection nasopharyngeal introducer and biopsy device comprising the same

Abstract

The application discloses an OCT (Optical Coherence Tomography) detection nasopharynx guide device, which comprises a guide hard tube and a guide soft tube; the inside of the guide hard tube is formed with a first guide channel and a second guide channel; one end of the first guide channel is formed with a first insertion opening, and the other end of the first guide channel is formed with a first passing opening, the first guide channel is suitable for the OCT probe to pass through and guide; one end of the second guide channel is formed with a second insertion opening, and the other end of the second guide channel is formed with a second passing opening, the second guide channel is suitable for the biopsy forceps to pass through and guide; the inside of the guide soft tube is formed with a containing channel suitable for containing the OCT probe, one end of the containing channel is closed, and the other end of the containing channel is formed with a connecting opening; one end of the guide soft tube is connected with one end of the guide hard tube, and the connecting opening of the containing channel is communicated with the first passing opening of the first guide channel. The application further discloses a biopsy device comprising the OCT detection nasopharynx guide device. The application can collect samples while observing, and has the characteristics of high detection and collection efficiency.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to an OCT nasopharyngeal guide and a biopsy device including the same. Background Technology

[0002] Optical Coherence Tomography (OCT) is an optical imaging technique based on the principle of weakly coherent light interference. It obtains two-dimensional or three-dimensional structures of biological tissues by detecting the back reflection or scattering signals of different tissues to incident weakly coherent light. The OCT optical scanning probe obtains images by rotating an internal fiber optic guidewire. Simultaneous rotation of the guidewire and axial movement of the probe allow for layer-by-layer scanning, enabling the acquisition of richer image information.

[0003] Nasopharyngeal biopsy is a commonly used method for confirming nasopharyngeal lesions, especially malignant tumors of the nasopharynx, and its histopathological diagnosis is the gold standard for final determination. Current nasopharyngeal biopsy methods include transoral and transnasal approaches. In the transoral approach, an assistant or the patient uses a tongue depressor to hold down the base of the tongue. The surgeon holds a direct or indirect nasopharyngoscope in their left hand and a nasopharyngeal biopsy forceps in their right. After visualizing the lesion, the forceps are inserted into the oral cavity, moving upwards from behind the uvula into the nasopharynx. The forceps are then opened at the anterior end to collect a biopsy sample for examination. This method has the following problems: sample collection cannot be performed simultaneously with observation, and both the detection and collection efficiency are low. Summary of the Invention

[0004] In order to overcome the shortcomings of the prior art, the present invention aims to provide an OCT nasopharyngeal guide and a biopsy device including the same, which can collect samples while observing, and has the characteristics of high detection and collection efficiency.

[0005] The first aspect of the present invention provides an OCT nasopharyngeal guide device, comprising:

[0006] The guide tube has an independent first guide channel and a second guide channel formed inside it along its axial direction; one end of the first guide channel forms a first insertion port and the other end forms a first exit port, and the first guide channel is adapted to allow an OCT probe to pass through and guide it; one end of the second guide channel forms a second insertion port and the other end forms a second exit port, and the second guide channel is adapted to allow a biopsy forceps to pass through and guide it.

[0007] The guide hose has an internal accommodating channel formed along its axial direction, suitable for accommodating an OCT probe. One end of the accommodating channel is closed, and the other end forms an inlet. One end of the guide hose is connected to one end of the guide tube, and the inlet of the accommodating channel is connected to the first outlet of the first guide channel.

[0008] In a first aspect of the invention, as a preferred embodiment, a gripping member for holding is further included, the gripping member being connected to the guide tube.

[0009] In a first aspect of the present invention, as a preferred embodiment, the gripping member includes a gripping portion and a guide portion formed above the gripping portion, wherein the guide portion has an independent third guide channel and a fourth guide channel formed inside it along its axial direction;

[0010] One end of the third guide channel forms a third insertion port, and the other end forms a third outlet. The third guide channel is adapted to allow an OCT probe to pass through and guide it. The third outlet of the third guide channel is connected to the first insertion port of the first guide channel.

[0011] One end of the fourth guide channel forms a fourth insertion port, and the other end forms a fourth exit port. The fourth guide channel is adapted to allow biopsy forceps to pass through and guide them. The fourth exit port of the fourth guide channel is connected to the second insertion port of the second guide channel.

[0012] In a first aspect of the invention, as a preferred embodiment, the guide tube and the gripper are detachably connected.

[0013] In a first aspect of the invention, as a preferred embodiment, a transition member is further included, one end of which is connected to the gripping member and the other end of which is connected to the guiding rigid tube; the interior of the transition member has a mutually independent fifth guide channel and a sixth guide channel formed along its axial direction.

[0014] One end of the fifth guide channel forms a fifth insertion port, and the other end forms a fifth exit port. The fifth guide channel is adapted to allow an OCT probe to pass through and guide it. The fifth insertion port of the fifth guide channel is connected to the third exit port of the third guide channel, and the fifth exit port of the fifth guide channel is connected to the first insertion port of the first guide channel.

[0015] One end of the sixth guide channel forms a sixth insertion port, and the other end forms a sixth exit port. The sixth guide channel is adapted to allow biopsy forceps to pass through and guide them. The sixth insertion port of the sixth guide channel is connected to the fourth exit port of the fourth guide channel, and the sixth exit port of the sixth guide channel is connected to the second insertion port of the second guide channel.

[0016] In a first aspect of the invention, as a preferred embodiment, one end of the transition member is detachably connected to the gripping member, and the other end is detachably connected to the guiding rigid tube.

[0017] In a first aspect of the invention, as a preferred embodiment, the guide hose has pleats formed on it.

[0018] In a first aspect of the invention, as a preferred embodiment, an inclined surface is formed at the second outlet of the second guide channel.

[0019] In a first aspect of the invention, as a preferred embodiment, the guide hose and the guide rigid tube are detachably connected.

[0020] The second objective of this invention is achieved by the following technical solution:

[0021] A biopsy device includes an OCT nasopharyngeal guide, biopsy forceps, and an OCT probe as described in one of the objectives of this invention; the OCT probe extends from a first guide channel into a receiving channel, and the forceps head extends from a second guide channel.

[0022] Compared to existing technologies, the advantages of this invention are as follows: The OCT nasopharyngeal guide of this invention includes a rigid guide tube and a flexible guide tube. The rigid guide tube has independent first and second guide channels formed along its axial direction. The first guide channel is suitable for the OCT probe to pass through and guide it; the second guide channel is suitable for the biopsy forceps to pass through and guide it. The flexible guide tube has a receiving channel formed along its axial direction suitable for accommodating the OCT probe. By setting independent first and second guide channels, the OCT probe extends into the receiving channel through the first guide channel, and obtains an image through rotational scanning of the internal fiber optic guide wire using the OCT optical scanning probe. Furthermore, the flexible guide tube can flexibly change its bending angle, allowing for 360-degree bending. The second guide channel allows the biopsy forceps to pass through, and it acquires sample information from specific locations by pulling and closing. Therefore, this invention can collect samples simultaneously with observation, exhibiting high detection and acquisition efficiency. Attached Figure Description

[0023] Figure 1 This is a three-dimensional view of the OCT detection nasopharyngeal guide in Example 1;

[0024] Figure 2 This is another perspective view of the OCT detection nasopharyngeal guide in Example 1;

[0025] Figure 3 This is a cross-sectional view of the OCT detection nasopharyngeal guide in Example 1;

[0026] Figure 4 This is a perspective view of the gripping component in Embodiment 1;

[0027] Figure 5 This is a perspective view of the transition component in Embodiment 1;

[0028] Figure 6 This is a perspective view of the guiding rigid tube in Embodiment 1;

[0029] Figure 7 This is a perspective view of the guide hose in Embodiment 1;

[0030] Figure 8 This is a perspective view of the biopsy device in Example 2.

[0031] In the picture:

[0032] 100. OCT detection nasopharyngeal guide;

[0033] 10. Guiding tube; 11. First guide channel; 111. First insertion port; 112. First exit port; 12. Second guide channel; 121. Second insertion port; 122. Second exit port;

[0034] 20. Guide hose; 201. Pleats; 21. Receiving channel; 211. Inlet;

[0035] 30. Holding component; 31. Holding part; 32. Guiding part; 321. Third guide channel; 3211. Third insertion port; 3212. Third through-outlet; 322. Fourth guide channel; 3221. Fourth insertion port; 3222. Fourth through-outlet;

[0036] 40. Transition component; 41. Fifth guide channel; 411. Fifth insertion port; 412. Fifth through-hole outlet; 42. Sixth guide channel; 421. Sixth insertion port; 422. Sixth through-hole outlet;

[0037] 200. Biopsy forceps; 210. Forceps head;

[0038] 300, OCT probe. Detailed Implementation

[0039] The present invention will now be further described in conjunction with the accompanying drawings and specific embodiments. It should be noted that, without conflict, the various embodiments or technical features described below can be arbitrarily combined to form new embodiments. Unless otherwise specified, the materials and equipment used in this embodiment are commercially available. Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this application, and should not be construed as limiting this application.

[0040] In the description of this application, it should be understood that the terms "upper," "lower," "front," "rear," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation on this application. In the description of this application, "a plurality of" means two or more, unless otherwise precisely specified.

[0041] In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "connected," "linked," and "connected" should be interpreted broadly. For example, they can refer to a fixed connection, a connection through an intermediary, or a connection within two elements or an interaction between two elements. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0042] The terms "first," "second," etc., in the specification, claims, and accompanying drawings of this application are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such process, method, product, or apparatus.

[0043] Example 1

[0044] Please refer to Figure 1-7 As shown, Embodiment 1 provides an OCT nasopharyngeal guide 100, including a guide rigid tube 10 and a guide flexible tube 20;

[0045] Specifically, the guide tube 10 has an independent first guide channel 11 and a second guide channel 12 formed inside it along its axial direction; one end of the first guide channel 11 forms a first insertion port 111 and the other end forms a first penetration port 112, and the first guide channel 11 is adapted to allow the OCT probe to pass through and guide it; one end of the second guide channel 12 forms a second insertion port 121 and the other end forms a second penetration port 122, and the second guide channel 12 is adapted to allow biopsy forceps to pass through and guide it;

[0046] Specifically, the guide tube 20 has a receiving channel 21 formed inside along its axial direction, suitable for accommodating the OCT probe. One end of the receiving channel 21 is closed, and the other end forms an inlet 211. One end of the guide tube 20 is connected to one end of the guide tube 10, and the inlet 211 of the receiving channel 21 communicates with the first outlet 112 of the first guide channel 11. Preferably, the guide tube 20 can be made entirely of transparent material, or a transparent area can be formed in a portion corresponding to the OCT probe.

[0047] Based on the above structure, this embodiment incorporates independent first guide channels 11 and second guide channels 12. The OCT probe extends into the receiving channel 21 through the first guide channel 11, where it obtains images through rotational scanning of the internal fiber optic guide wire. Furthermore, the guide tube 20 can flexibly change its bending angle, allowing for 360-degree bending. The second guide channel 12 allows biopsy forceps to pass through, and its pull-close mechanism collects sample information from specific locations. Therefore, this embodiment enables sample collection during observation, exhibiting high detection and collection efficiency.

[0048] In a preferred embodiment of the present invention, in order to facilitate gripping and ensure the stability and accuracy of operation, the OCT nasopharyngeal guide 100 of this embodiment further includes a gripping member 30 for gripping, and the gripping member 30 is connected to the guide tube 10.

[0049] In a preferred embodiment of the present invention, the grip member 30 includes a grip portion 31 and a guide portion 32 formed above the grip portion 31;

[0050] Specifically, the grip 31 is a handle, which may have multiple sub-grips arranged in the vertical direction. Each sub-grip may be shaped to fit the corresponding fingertip. For example, there may be four sub-grips, and the shapes of the four sub-grips from top to bottom may fit the shapes of the fingertips from the index finger to the little finger. This further facilitates the user's grip on the handle, increases grip comfort, and effectively prevents relative slippage between the hand and the handle.

[0051] Specifically, the interior of the guide section 32 has a third guide channel 321 and a fourth guide channel 322 that are independent of each other along its axial direction;

[0052] Furthermore, one end of the third guide channel 321 forms a third insertion port 3211, and the other end forms a third through-hole 3212. The third guide channel 321 is adapted to allow the OCT probe to pass through and guide it. The third through-hole 3212 of the third guide channel 321 is connected to the first insertion port 111 of the first guide channel 11. In this way, the third guide channel 321 can guide the OCT probe into the first guide channel 11, which facilitates the installation of the OCT probe and the guidance and positioning of the OCT probe.

[0053] Furthermore, one end of the fourth guide channel 322 forms a fourth insertion port 3221, and the other end forms a fourth through-hole 3222. The fourth guide channel 322 is adapted for the biopsy forceps to pass through and guide them; the fourth through-hole 3222 of the fourth guide channel 322 communicates with the second insertion port 121 of the second guide channel 12. In this way, the fourth guide channel 322 can guide the biopsy forceps into the second guide channel 12, which facilitates the installation of the biopsy forceps and the guiding and positioning of the biopsy forceps.

[0054] In a preferred embodiment of the present invention, the guide tube 10 and the gripper 30 are detachably connected. Specifically, the two can be connected by a snap-fit ​​connection, a threaded connection, a plug-in connection, or other detachable methods. In this way, the guide tube 10 can be designed as a disposable structure, facilitating timely replacement.

[0055] In a preferred embodiment of the present invention, a transition member 40 is further included, one end of which is connected to the gripping member 30 and the other end of which is connected to the guiding rigid tube 10.

[0056] Specifically, the interior of the transition member 40 has a fifth guide channel 41 and a sixth guide channel 42 that are independent of each other along its axial direction;

[0057] Furthermore, one end of the fifth guide channel 41 forms a fifth insertion port 411, and the other end forms a fifth through port 412. The fifth guide channel 41 is adapted to allow the OCT probe to pass through and guide it. The fifth insertion port 411 of the fifth guide channel 41 is connected to the third through port 3212 of the third guide channel 321, and the fifth through port 412 of the fifth guide channel 41 is connected to the first insertion port 111 of the first guide channel 11. In this way, the fifth guide channel 41 can guide the OCT probe passing through the third guide channel 321 into the first guide channel 11, which facilitates the installation of the OCT probe and the guidance and positioning of the OCT probe.

[0058] Furthermore, one end of the sixth guide channel 42 forms a sixth insertion port 421, and the other end forms a sixth through-hole 422. The sixth guide channel 42 is adapted for the biopsy forceps to pass through and for guiding them. The sixth insertion port 421 of the sixth guide channel 42 is connected to the fourth through-hole 3222 of the fourth guide channel 322, and the sixth through-hole 422 of the sixth guide channel 42 is connected to the second insertion port 121 of the second guide channel 12. In this way, the sixth guide channel 42 can guide the biopsy forceps passing through the fourth guide channel 322 into the second guide channel 12, which facilitates the installation of the biopsy forceps and the guiding and positioning of the biopsy forceps.

[0059] In a preferred embodiment of the present invention, one end of the transition member 40 is detachably connected to the gripper 30, and the other end is detachably connected to the guide tube 10. Specifically, the two can be connected by a snap-fit ​​connection, threaded connection, plug-in connection, or other detachable methods. In this way, the guide tube 10 can be designed as a disposable structure, facilitating timely replacement.

[0060] In a preferred embodiment of the invention, a pleat 201 is formed on the guide hose 20. This allows the guide hose 20 to be formed into a bent tube structure.

[0061] In a preferred embodiment of the present invention, an inclined surface is formed at the second outlet 122 of the second guide channel 12. This provides better guidance and prevents the second outlet 122 from forming a sharp point that could damage human tissue.

[0062] In a preferred embodiment of the present invention, the guide hose 20 and the guide rigid tube 10 are detachably connected. Specifically, they can be connected by a snap-fit ​​connection, threaded connection, plug-in connection, or other detachable methods. In this way, both the guide hose 20 and the guide rigid tube 10 can be designed as disposable structures, facilitating timely replacement.

[0063] In a preferred embodiment of the present invention, the outer diameter of the guide tube 20 is 4 mm, the distance from the pleated portion 201 of the guide tube 20 to the closed end of the guide tube 20 is 15 mm, the outer diameter of the guide tube 10 is 7.3 mm, and the total length of the OCT nasopharyngeal guide is 280 mm.

[0064] Example 2

[0065] Example 2 is an improvement based on Example 1.

[0066] Please refer to Figure 3 and Figure 8As shown, Embodiment 2 provides a biopsy device, including the OCT nasopharyngeal guide 100, biopsy forceps 200, and OCT probe 300 from Embodiment 1. The OCT probe 300 extends from the first guide channel 11 into the receiving channel 21, and the forceps head 210 of the biopsy forceps 200 extends from the second guide channel 12. Both the OCT probe and the biopsy forceps can employ existing conventional structures. For example, the OCT probe can be an OCT optical scanning probe, which obtains images by rotating and scanning through an internal fiber optic guidewire. The biopsy forceps are then pulled and closed to collect sample information from specific locations.

[0067] Although only certain components and embodiments of this application have been illustrated and described, many modifications and alterations (e.g., variations in the size, dimensions, structure, shape and proportion of the various elements, installation arrangement, material use, color, orientation, etc.) will be conceived by those skilled in the art without actually departing from the scope and spirit of the claims.

[0068] Finally, it should be noted that the above embodiments are merely preferred embodiments of the present invention and should not be construed as limiting the scope of protection of the present invention. Any non-substantial changes and substitutions made by those skilled in the art based on the present invention shall fall within the scope of protection claimed by the present invention.

Claims

1. An OCT nasopharyngeal guide device, characterized in that, include: The guide tube has an independent first guide channel and a second guide channel formed inside it along its axial direction; one end of the first guide channel forms a first insertion port and the other end forms a first exit port, and the first guide channel is adapted to allow an OCT probe to pass through and guide it; one end of the second guide channel forms a second insertion port and the other end forms a second exit port, and the second guide channel is adapted to allow a biopsy forceps to pass through and guide it. The guide hose has an internal accommodating channel formed along its axial direction, suitable for accommodating an OCT probe. One end of the accommodating channel is closed, and the other end forms an inlet. One end of the guide hose is connected to one end of the guide tube, and the inlet of the accommodating channel communicates with the first outlet of the first guide channel. The guide hose has pleats. A gripper is provided for gripping and is detachably connected to the guide tube. The gripper includes a gripping portion and a guide portion formed above the gripping portion. The guide portion has two independent guide channels formed along its axial direction: a third guide channel and a fourth guide channel. One end of the third guide channel forms a third insertion port, and the other end forms a third exit port. The third guide channel is adapted for allowing an OCT probe to pass through and for guiding it. The third exit port of the third guide channel communicates with the first insertion port of the first guide channel. One end of the fourth guide channel forms a fourth insertion port, and the other end forms a fourth exit port. The fourth guide channel is adapted for allowing biopsy forceps to pass through and for guiding it. The fourth exit port of the fourth guide channel communicates with the second insertion port of the second guide channel. A transition piece, one end of which is detachably connected to the gripper, and the other end of which is detachably connected to the guide tube; the interior of the transition piece has a fifth guide channel and a sixth guide channel formed along its axial direction; one end of the fifth guide channel forms a fifth insertion port, and the other end forms a fifth exit port, the fifth guide channel being adapted for OCT probes to pass through and guide; the fifth insertion port of the fifth guide channel communicates with the third exit port of the third guide channel, and the fifth exit port of the fifth guide channel communicates with the first insertion port of the first guide channel; one end of the sixth guide channel forms a sixth insertion port, and the other end forms a sixth exit port, the sixth guide channel being adapted for biopsy forceps to pass through and guide; the sixth insertion port of the sixth guide channel communicates with the fourth exit port of the fourth guide channel, and the sixth exit port of the sixth guide channel communicates with the second insertion port of the second guide channel.

2. The OCT nasopharyngeal guide device according to claim 1, characterized in that, An inclined surface is formed at the second exit of the second guide channel.

3. The OCT nasopharyngeal guide device according to claim 1, characterized in that, The guide hose and the guide rigid tube are detachably connected.

4. A biopsy device, characterized in that, Includes the OCT nasopharyngeal guide, biopsy forceps, and OCT probe as described in any one of claims 1-3; the OCT probe extends from the first guide channel into the receiving channel, and the forceps head extends from the second guide channel.

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