A carotid implant valve delivery system and method of delivering a valve

Abstract

The application discloses a carotid artery implanted valve delivery system and a valve delivery method. The valve delivery system comprises a control handle 100 at a proximal end, a tube assembly 200 connected with the control handle 100 and extending to a distal end, and an outer sheath 300 for guiding the tube assembly 200 to pass through a body. The tube assembly 200 has a length L1 extending to the distal end from the control handle 100, and the length L1 is at least adapted to a distance between a carotid artery surface puncture point 401 and an aortic valve 403. The outer sheath 300 has a length L2, and the length L2 is at least adapted to a distance between the carotid artery surface puncture point 401 and an aortic arch 402.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and in particular to a carotid artery implantation valve delivery system and valve delivery method. Background Technology

[0002] With an aging population, the incidence of valvular heart disease has increased significantly, primarily due to lesions in the patient's native heart valve. These lesions include narrowing, leakage, and regurgitation of the native heart valve. Current experimental and clinical results indicate that drug treatment for native heart valve disease is ineffective, while surgery yields good results. Surgery mainly involves valve replacement. During valve replacement, the native valve can be removed and replaced with a bioprosthetic or mechanical valve. Mechanical valves require lifelong anticoagulant medication to prevent blood clots, and a ticking sound can usually be heard through the chest cavity. Bioprosthetic valves generally do not require this medication. Tissue valves can utilize valves from pigs or cattle and are typically attached to a synthetic ring that is fixed to the patient's heart valve annulus.

[0003] In traditional treatment, valve implantation is typically achieved surgically, such as through open-heart surgery under general anesthesia. An incision is made through the patient's sternum, and cardiopulmonary bypass is established to allow for valve implantation. Valve replacement surgery is a highly invasive procedure with significant associated risks, including bleeding, infection, stroke, heart attack, arrhythmia, kidney failure, adverse reactions to anesthetic drugs, and sudden death. A 2-5% mortality rate occurs during the procedure, and the average hospital stay is between one and two weeks, with full recovery requiring weeks to months.

[0004] Therefore, in recent years, catheter-assisted valve implantation has gradually become a mainstream treatment method. TAVR (Transcatheter Aortic Valve Replacement) surgery involves the placement of a new valve at the aortic valve location under the guidance of a catheter. The physician inserts the catheter into a blood vessel (usually the femoral artery near the groin) and advances it to the aortic valve area. When in the correct position, the frame inflates by blowing up a balloon, at which point the artificial valve opens and begins to function. Catheter-assisted implantation has many advantages known to those skilled in the art. For example, patent document CN101309654B discloses a delivery system and method for delivering an artificial heart valve to the aortic valve annulus. The system includes a balloon catheter with a control mechanism for delivering a balloon-expandable artificial heart valve to the aortic annulus in an antegrade manner via an inlet device.

[0005] Similar to related technologies, there are two implantation routes for the aortic valve: the apex of the heart ("transapical") and the groin vessel ("transfemoral"). In practice, the catheter is usually inserted through the femoral artery. However, the inventors discovered that because the femoral artery is only of medium diameter, the catheter used must not exceed approximately 28 Fr. During TAVR surgery, approximately 12% of patients have insufficient femoral artery diameter for the procedure. To complete the surgery, the surgeon inserts the valve through the carotid artery, but the current overall design of the delivery system is based on the femoral artery route, which is highly unsuitable for carotid artery insertion, resulting in unsatisfactory surgical outcomes and making the treatment process difficult. Summary of the Invention

[0006] To address the limitations of femoral artery intervention, this application provides a carotid artery-implanted valve delivery system.

[0007] A carotid artery implantation valve delivery system includes a proximal control handle, a tubular assembly connected to the control handle and extending distally, and an outer sheath for guiding the tubular assembly through the body.

[0008] The tubular assembly has a length L1 extending distally from the control handle, the length L1 being at least adapted to the distance between the carotid artery puncture site and the aortic valve.

[0009] The outer sheath has a length L2, which is at least adapted to the distance between the carotid artery puncture site and the aortic arch.

[0010] This application also provides a carotid artery implantation valve delivery system, including a control handle located at the proximal end, a tubular assembly connected to the control handle and extending distally, and an outer sheath for guiding the tubular assembly through the body;

[0011] The tube assembly has a length L1 extending distally from the control handle, and the outer sheath has a length L2. The length L1 is less than or equal to 80 cm, and the length L2 is 20 to 40 cm shorter than the length L1.

[0012] Several alternative methods are provided below, but they are not intended as additional limitations on the overall solution above. They are merely further additions or optimizations. Provided there are no technical or logical contradictions, each alternative method can be combined individually with respect to the overall solution above, or multiple alternative methods can be combined with each other.

[0013] Optionally, the length L1 is 40 to 60 cm.

[0014] Optionally, the length L1 is 45 to 55 cm.

[0015] Optionally, the length L1 is 50cm.

[0016] Optionally, the length L2 is 12 to 25 cm.

[0017] Optionally, the length L2 is 12 to 20 cm.

[0018] Optionally, the length L2 is 15cm.

[0019] Optionally, the outer sheath has length indicators arranged along the axial direction.

[0020] Optionally, the diameter of the outer sheath is 19–28 Fr.

[0021] Optionally, the junction of the carotid artery and the aortic arch is designated as position C1, and the length L2 is at least adapted to the distance between the carotid artery puncture site and position C1.

[0022] Optionally, the junction of the carotid artery and the aortic arch is designated as position C1, the aortic valve as position C2, and the area near the midpoint between position C1 and position C2 is designated as position C3. The length L2 is at least appropriate to the distance between the carotid artery puncture site and position C3.

[0023] Optionally, the tube assembly includes a core tube and a sheath that are nested inside and out and can slide axially relative to each other under the drive of the control handle, wherein the interventional device is loaded in the distal portion of the core tube and has a loaded state that is housed in the sheath, and has a released state that expands radially outward after the sheath is retracted.

[0024] Optionally, the core tube is fitted with a locking device for connecting an interventional device, and the distal end of the core tube extends further out of the locking device and is fixed with a guide head. The position between the guide head and the locking device serves as the loading position for the interventional device.

[0025] Optionally, the outer periphery of the locking member is provided with multiple limiting grooves, and the interventional instrument has a connecting ear that is inserted into the limiting groove. The limiting groove is used for axial limiting of the interventional instrument, allowing the interventional instrument to be released and disengaged only after radial expansion.

[0026] Optionally, the locking element is also fixed with a pressure strip that mates with each limiting groove. The pressure strip is restrained by the sheath tube to confine the connecting ear within the limiting groove.

[0027] Optionally, the interventional device is a self-expanding type.

[0028] Optionally, the interventional device is a balloon-expandable type, and the core tube is provided with a balloon that can be expanded by injected fluid.

[0029] Optionally, the proximal end of the outer sheath is connected to a grip handle, and the grip handle has a bypass tube communicating with the outer sheath.

[0030] Optionally, the outer sheath itself is a straight extension, with a first curved section formed in a predetermined manner joined at the distal end of the straight extension. The angle between the first curved section and the straight extension is 10 degrees to 120 degrees, preferably 90 degrees to 120 degrees.

[0031] Optionally, the distal end of the first curved segment is also connected to a second curved segment constructed in a predetermined manner, and the angle between the second curved segment and the direction of the distal end of the first curved segment is 20 degrees to 40 degrees.

[0032] This application also provides a method for carotid artery valve delivery, including:

[0033] An external sheath is used to establish a passageway by puncturing the carotid artery from the surface, passing through the carotid artery, and extending at least into the aortic arch.

[0034] Using the control handle, the tube assembly loaded with the interventional device is traversed through the passageway into the body until the distal end of the tube assembly extends out of the outer sheath and reaches the predetermined position;

[0035] Release the interventional device within the catheter assembly and position the interventional device at the aortic valve.

[0036] The carotid artery implantation valve delivery method described in this application is implemented using the carotid artery implantation valve delivery system described in this application. Attached Figure Description

[0037] Figure 1a This is a schematic diagram of a valve delivery system in one embodiment;

[0038] Figure 1b This is a schematic diagram of the core tube structure;

[0039] Figure 1c This is a schematic diagram of the fitting relationship between the pipe components;

[0040] Figure 1d A schematic diagram showing the fit between the tubular assembly and the interventional device.

[0041] Figure 1e This is a schematic diagram of the interventional device release process;

[0042] Figure 1f This is a schematic diagram showing the state of the interventional device after deployment;

[0043] Figure 2a This is a schematic diagram of the structure after the outer sheath and the support sheath are assembled in one embodiment;

[0044] Figure 2b for Figure 2a Schematic diagram of the structure of the inner and outer sheaths and the grip handle;

[0045] Figure 3a This is a schematic diagram showing the outer sheath reaching position C1 from the right carotid artery;

[0046] Figure 3b A schematic diagram showing the tube assembly reaching its working position from the right carotid artery;

[0047] Figure 3c A schematic diagram showing the release of the interventional device from the right carotid artery via the catheter assembly;

[0048] Figure 4 This is a schematic diagram showing the outer sheath reaching position C3 from the right carotid artery;

[0049] Figure 5a This is a schematic diagram showing the outer sheath reaching position C1 from the left carotid artery;

[0050] Figure 5b A schematic diagram showing the tube assembly reaching its working position from the left carotid artery;

[0051] Figure 5c A schematic diagram showing the release of the interventional device from the left carotid artery via the catheter assembly;

[0052] Figure 6 This is a schematic diagram showing the outer sheath reaching position C3 from the left carotid artery.

[0053] The annotations in the figure are explained as follows:

[0054] 100. Control handle;

[0055] 200. Pipe assembly;

[0056] 201. Core tube;

[0057] 202. Sheath;

[0058] 203. Locking components;

[0059] 204. Guide head;

[0060] 205. Loading position;

[0061] 206. Limiting groove;

[0062] 207. Pressing strip;

[0063] 300. Outer sheath;

[0064] 301. Hold the handle;

[0065] 302. Bypass pipe;

[0066] 303. Support sheath;

[0067] 401. Carotid artery puncture site on the body surface;

[0068] 402. Aortic arch;

[0069] 403. Aortic valve;

[0070] 404. Left carotid artery;

[0071] 405. Right carotid artery;

[0072] 500. Interventional devices;

[0073] 501. Connecting ear. Detailed Implementation

[0074] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0075] It should be noted that when a component is said to be "connected" to another component, it can be directly connected to the other component or it can be connected to a component in between. When a component is said to be "set on" another component, it can be directly set on the other component or it may be set to a component in between.

[0076] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the scope of the application. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0077] Referring to the accompanying drawings, one embodiment of this application provides a carotid artery-based valve delivery system. The valve delivery system has a distal end and a proximal end, with the distal end closer to the lesion and the proximal end closer to the operator. To perform interventional surgery and valve delivery when the femoral artery is narrow, this embodiment improves upon existing valve delivery systems. This valve delivery system is applicable not only to the aortic valve but also to other sites such as the mitral valve. The following embodiments primarily use the aortic valve as an example, employing an interventional device for the aortic valve. In practical scenarios, interventional devices with appropriate structures can be used depending on the lesion location, and all can be inserted via the carotid artery.

[0078] The interventional device itself can be self-expanding. In other embodiments, the interventional device is a balloon-expanding type, with a balloon on the core tube that can be inflated by injected fluid.

[0079] Interventional devices, taking aortic valve devices as an example, include stents, with leaflets inside the stents, such as the common tricuspid valve, which can open and close to control blood flow.

[0080] The valve delivery system in this application embodiment includes a control handle 100 located at the proximal end, a tube assembly 200 connected to the control handle 100 and extending distally, and an outer sheath 300 for guiding the tube assembly 200 through the body.

[0081] The tubing assembly 200 has a length L1 extending distally from the control handle 100, the length L1 being at least adapted to the distance between the carotid artery puncture site 401 and the aortic valve 403.

[0082] The outer sheath 300 has a length L2, which is at least adapted to the distance between the carotid artery puncture site 401 and the aortic arch 402.

[0083] The outer sheath 300 is used to establish a passageway to prevent damage to internal tissues during the reciprocating motion of the tubular assembly 200. Generally, the length of the outer sheath 300 should be long enough to extend into the aortic arch 402, after which the tubular assembly 200 enters the predetermined position through the passageway. The length L1 is greater than the length L2 and can extend from the distal end of the passageway to the lesion site.

[0084] The tube assembly 200 includes a core tube 201 and a sheath tube 202 that are nested inside and out and can slide axially relative to each other under the drive of the control handle 100. The interventional device 500 is loaded in the distal part of the core tube 201 and has a loaded state that is housed in the sheath tube 202, and has a released state that expands radially outward after the sheath tube 202 is retracted.

[0085] The interventional device 500 is mounted and connected to the core tube 201. When the sheath tube 202 slides axially relative to the core tube 201, the interventional device 500 can be housed or exposed to enable the release of the interventional device 500 and, if necessary, its retrieval.

[0086] In order to load and connect the interventional device 500, a locking member 203 for connecting the interventional device 500 is installed on the core tube 201. The locking member 203 extends further from the distal end of the core tube 201 and a guide head 204 is fixed thereon. The position between the guide head 204 and the locking member 203 serves as the loading position 205 for the interventional device 500.

[0087] The locking element 203 can have a variety of different structures. For example, it can be connected to the connecting ear 501 on the interventional device 500 in the form of a groove, or in the form of a radially outward protruding head, or in the form of a wire control, using a long wire or wire loop to connect to the interventional device 500. Regardless of the form, its purpose is to achieve cooperation with the connecting ear 501 of the interventional device 500.

[0088] The distal end of the guide head 204 has a converging rounded head structure to facilitate its insertion and movement within the body. The locking member 203 has one or more limiting grooves 206 on its outer periphery. The interventional instrument 500 has connecting ears 501 that fit into these limiting grooves 206. The limiting grooves 206 are used for axial limiting of the interventional instrument 500, allowing it to release only after radial expansion. To prevent the connecting ears 501 from accidentally dislodging or suddenly protruding outwards and injuring tissue during release, pressure strips 207 that mate with each limiting groove 206 are fixed at the locking member 203. After loading, the pressure strips 207 are restrained by the sheath 202, confining the connecting ears 501 within the limiting grooves 206. This further enhances safety; during release, the flexible pressure strips 207 fold outwards, allowing the connecting ears 501 to disengage from the locking member 203.

[0089] The control handle can drive the core tube 201 and the sheath tube 202 to slide axially relative to each other. In one embodiment, the control handle includes a control component and a front handle; wherein the control component includes:

[0090] A first support body fixed relative to the front handle;

[0091] It is slidably mounted on the first support body, and the proximal end of the sheath 202 is fixed to the first connector;

[0092] A first driving member that is movably mounted on the first support and drives the first connecting member to slide;

[0093] The pipe joint is fixedly installed at the proximal end of the second support body. The proximal end of the core tube 201 passes through the sheath tube 202 and is fixed to the pipe joint.

[0094] In one embodiment, the first driving member is rotatably sleeved on the outer periphery of the first support body, and a limiting mechanism is provided between the front handle and the first driving member to limit the rotation angle of the first driving member.

[0095] The first support body is cylindrical, and the side wall of the first support body has a guide bar hole extending axially. The first connector is slidably installed inside the first support body. The first connector has a guide key extending radially out of the guide bar hole. The inner wall of the first drive member has a threaded structure that mates with the guide key.

[0096] When the first driving member rotates, it can drive the sheath tube 202 to slide axially relative to the core tube 201 through the first connecting member.

[0097] One embodiment of this application provides a valve delivery system for carotid artery implantation. The valve delivery system is not limited to the delivery of aortic valve devices. It includes a control handle 100 located at the proximal end, a tubular assembly 200 connected to the control handle 100 and extending distally, and an outer sheath 300 for guiding the tubular assembly 200 through the body.

[0098] The tube assembly 200 has a length L1 extending distally from the control handle 100, and the outer sheath 300 has a length L2. The length L1 is less than or equal to 80 cm, and the length L2 is 20 to 40 cm shorter than the length L1.

[0099] Since it enters the body through the carotid artery and reaches the heart or surrounding area, the lengths L1 and L2 can be adjusted accordingly to facilitate operation.

[0100] In the preferred embodiments described above, the length L1 is 40-60cm, for example, 45-55cm, or 50cm.

[0101] Accordingly, in the preferred embodiment, the length L2 is 12 to 25 cm, for example, the length L2 is 12 to 20 cm, or for example, the length L2 is 15 cm.

[0102] In one embodiment, the junction of the carotid artery and the aortic arch 402 is at location C1, and the length L2 is at least appropriate to the distance between the carotid artery puncture point 401 and location C1, that is, extending to location C1.

[0103] In one embodiment, the junction of the carotid artery and the aortic arch 402 is location C1, the aortic valve 403 is location C2, and the area near the midpoint between location C1 and location C2 is location C3. The length L2 is at least appropriate to the distance between the carotid artery puncture point 401 and location C3, that is, extending to location C3.

[0104] For ease of identification or measurement, in one embodiment the outer sheath 300 has length indicators arranged along the axial direction.

[0105] The delivery system of this application uses carotid artery intervention, which can not only meet the needs of smaller-sized external sheath 300 interventions, but also adapt to larger-sized external sheath 300 interventions compared to femoral artery interventions, such as external sheath 300 with a diameter of 19-28 Fr.

[0106] The outer sheath 300 has a handle 301 attached to its proximal end, and the handle 301 has a bypass tube 302 that communicates with the outer sheath 300. The outer sheath 300 and the handle 301 are axially connected, and the connection area is sealed by a hemostatic valve. In use, the axially connected part can be inserted into the support sheath 303, and blood is prevented from flowing out under the action of the hemostatic valve. The distal end of the support sheath 303 gradually narrows to form a pointed structure so as to pass through the body. When the outer sheath 300 and the support sheath 303 are inserted into the body and in place, the support sheath 303 can be retracted, leaving only the outer sheath 300 in the body.

[0107] In one embodiment, the outer sheath itself is a straight extension, and a first curved section formed in a predetermined manner is joined at the distal end of the straight extension. The angle between the first curved section and the straight extension is 10 degrees to 120 degrees, preferably 90 degrees to 120 degrees.

[0108] In another embodiment, the distal end of the first curved segment is further connected to a second curved segment constructed in a predetermined manner, and the angle between the second curved segment and the direction of the distal end of the first curved segment is 20 degrees to 40 degrees.

[0109] In a preferred embodiment, the first bending segment and the second bending segment bend in opposite directions. The first bending segment and the second bending segment may be coplanar or non-coplanar. A straight-line transition segment may be provided between them, for example, the length of the transition segment is 3 to 6 cm.

[0110] The design of each curved segment can create a more suitable passageway towards the mitral valve or other areas requiring a significant bend. The length of the aforementioned outer sheath 300 can be understood as the length of the straight extension segment. If all curved segments are included, the total length can reach 40-60 cm, for example, 45 cm.

[0111] One embodiment of this application also provides a method for delivering a valve via carotid artery implantation, comprising:

[0112] An external sheath 300 is used to establish a passageway from the carotid artery puncture point 401 on the body surface, through the carotid artery and extending at least into the aortic arch 402.

[0113] In one embodiment, the distal end of the outer sheath 300 may extend to the junction of the carotid artery and the aortic arch 402, i.e., position C1. In other embodiments, the distal end of the outer sheath 300 may extend to position C3.

[0114] In one embodiment, the outer sheath 300 enters the aortic arch 402 along the left carotid artery 404; in other embodiments, the outer sheath 300 enters the aortic arch 402 along the right carotid artery 405.

[0115] After the outer sheath 300 is in place, the tube assembly 200 carrying the interventional device 500 is passed through the body via the passage channel using the control handle 100 until the distal end of the tube assembly 200 extends out of the outer sheath 300 and reaches the predetermined position.

[0116] Taking the aortic valve 403 as an example, when the outer sheath 300 reaches the predetermined position, the position of the interventional device 500 corresponds to the position of the aortic valve 403.

[0117] By keeping the core tube 201 stationary and retracting the sheath 202 proximally, the interventional device 500 is gradually exposed, i.e., the interventional device 500 is released from the tube assembly 200 and positioned at the aortic valve 403.

[0118] The carotid artery implantation valve delivery method of this embodiment can be implemented using the carotid artery implantation valve delivery system described in the above embodiments.

[0119] In this application, unless otherwise expressly specified and limited, the first feature being "on" or "below" the second feature may be in direct contact with the first feature and the second feature, or indirect contact between the first feature and the second feature through an intermediate medium.

[0120] Furthermore, "above," "on top of," and "above" the first feature in relation to the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. Similarly, "below," "under," and "beneath" the first feature in relation to the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0121] In the description of this specification, references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0122] The technical features of the embodiments described above can be combined arbitrarily. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as the combination of these technical features does not contradict each other, it should be considered to be within the scope of this specification. When technical features of different embodiments are embodied in the same drawing, it can be regarded as the drawing also disclosing examples of combinations of the various embodiments involved.

[0123] The embodiments described above are merely examples of several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these modifications and improvements all fall within the protection scope of this application.

Claims

1. A carotid artery implantation valve delivery system, characterized in that, It includes a control handle located at the proximal end, a tube assembly connected to the control handle and extending distally, and an outer sheath for guiding the tube assembly through the body; The tubular assembly has a length L1 extending distally from the control handle, the length L1 being at least adapted to the distance between the carotid artery puncture site and the aortic valve. The outer sheath has a length L2, which is at least adapted to the distance between the carotid artery puncture site and the aortic arch. The length L1 is 40-60cm; the length L2 is 12-25cm; The outer sheath itself is a straight extension segment, and a first curved segment constructed in a predetermined manner is joined at the distal end of the straight extension segment. The angle between the first curved segment and the straight extension segment is 10 degrees to 120 degrees. The distal end of the first curved segment is also connected to a second curved segment constructed in a predetermined manner. The angle between the second curved segment and the direction of the distal end of the first curved segment is 20 degrees to 40 degrees. The first curved segment and the second curved segment bend in opposite directions, and a straight transition segment with a length of 3 to 6 cm is provided between the first curved segment and the second curved segment.

2. A carotid artery implantation valve delivery system, characterized in that, Includes a control handle located at the proximal end, a tube assembly connected to the control handle and extending distally, and an outer sheath for guiding the tube assembly through the body; The tube assembly has a length L1 extending distally from the control handle, and the outer sheath has a length L2, wherein the length L1 is 40-60 cm and the length L2 is 12-25 cm; The outer sheath itself is a straight extension segment, and a first curved segment constructed in a predetermined manner is joined at the distal end of the straight extension segment. The angle between the first curved segment and the straight extension segment is 10 degrees to 120 degrees. The distal end of the first curved segment is also connected to a second curved segment constructed in a predetermined manner. The angle between the second curved segment and the direction of the distal end of the first curved segment is 20 degrees to 40 degrees. The first and second curved sections bend in opposite directions, and a straight transition section with a length of 3 to 6 cm is provided between the first and second curved sections.

3. The carotid artery implantation valve delivery system as described in claim 1 or 2, characterized in that, The junction of the carotid artery and the aortic arch is located at position C1, and the length L2 is at least appropriate to the distance between the carotid artery puncture point on the body surface and the location C1.

4. The carotid artery implantation valve delivery system as described in claim 1 or 2, characterized in that, The junction of the carotid artery and the aortic arch is designated as position C1, the aortic valve as position C2, and the area near the midpoint between position C1 and position C2 is designated as position C3. The length L2 is at least appropriate to the distance between the carotid artery puncture site and position C3.

5. The carotid artery implantation valve delivery system as described in claim 1 or 2, characterized in that, The tubular assembly includes a core tube and a sheath that are nested together and can slide axially relative to each other under the drive of the control handle. The interventional device is loaded in the distal portion of the core tube and has a loaded state that is housed in the sheath, and a released state that expands radially outward after the sheath is retracted.

6. The carotid artery implantation valve delivery system as described in claim 5, characterized in that, The core tube is fitted with a locking device for connecting an interventional device. The distal end of the core tube extends further out of the locking device and is fixed with a guide head. The position between the guide head and the locking device serves as the loading position for the interventional device.

7. The carotid artery implantation valve delivery system as described in claim 6, characterized in that, The outer periphery of the locking member is provided with multiple limiting grooves, and the interventional device has a connecting ear that is inserted into the limiting groove. The limiting groove is used to limit the axial movement of the interventional device, allowing the interventional device to be released and detached only after radial expansion.

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