An air purification composition containing Chinese herbal medicine volatile oil, an air purification device and a preparation method

Abstract

The present application relates to the field of air purification technology, and more particularly to an air purification composition containing Chinese herbal medicine volatile oil, an air purification device and a preparation method. The air purification composition comprises a chlorine dioxide slow-release gel and a Chinese herbal medicine volatile oil slow-release system, wherein the components of the chlorine dioxide slow-release gel comprise an aqueous oxalic acid solution, sodium chlorite, porous nanomaterial, hydroxypropyl methylcellulose K4M and ethyl cellulose, and the Chinese herbal medicine volatile oil slow-release system comprises Chinese herbal medicine volatile oil and a slow-release matrix material. The air purification composition is slowly released by chlorine dioxide and Chinese herbal medicine volatile oil together, has effective and persistent bactericidal action, and can also undergo oxidation-reduction reactions with various organic and inorganic substances in the air to achieve the purpose of decomposing odors and purifying air.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of air purification technology, in particular to an air purification composition containing volatile oil of Chinese herbal medicine and a preparation method thereof, and an air purification device made of the air purification composition. BACKGROUND

[0002] Toxic gases, suspended particles, bacteria, viruses and other harmful substances in the air are a constant threat to human health. In particular, for closed environments such as indoor and in-vehicle environments, the impact of air quality on human health is particularly evident. Therefore, air disinfection and purification technology for closed environments is attracting increasing attention.

[0003] Traditional air disinfection and purification technologies include activated carbon adsorption, active oxygen technology, negative oxygen ion purification technology, and electrostatic dust collection technology. Activated carbon adsorption uses micropores for physical and chemical adsorption, but it is easy to saturate and slow to adsorb, and when the temperature rises or the air flows in and out of the activated carbon, the adsorbed pollutants may be released again, greatly reducing the purification effect; active oxygen technology uses ozone to kill bacteria in the air, which is thorough and fast, but excessive ozone can cause symptoms such as sore throat, chest tightness, and coughing, and can also induce bronchitis, emphysema, and nerve poisoning; negative oxygen ion purification technology uses negative oxygen ions to neutralize positively charged air dust and make it settle, thereby purifying the air, but negative oxygen ions have a very short lifespan in the air and need to be continuously released, so the negative ion release device needs to be continuously running; electrostatic dust collection technology uses high-voltage static electricity to adsorb particulate pollutants in the air, such as dust, soot, pollen, cigarette smoke, and kitchen fumes, but it is only effective for large particle gases such as particulate matter, and it can also produce ozone and cause static electricity on the floor, walls, and furniture around the electrostatic dust collection instrument, increasing the cleaning burden.

[0004] As can be seen, traditional air purification technologies have limitations and cannot simultaneously achieve safety, non-toxicity, significant purification effect, and multiple functions.

[0005] Chlorine dioxide is safe, non-toxic, highly efficient, and broad-spectrum, and can be used for air disinfection and purification. However, chlorine dioxide is active and has a short release period and is not easy to store, which restricts its use as an active substance for air purification. SUMMARY

[0006] In view of the problems that current air disinfection and purification products cannot simultaneously achieve safety, non-toxicity, significant purification effect, and multiple functions, and chlorine dioxide has a short release period and is not easy to store, the present application provides an air purification composition containing volatile oil of Chinese herbal medicine, an air purification device, and a preparation method.

[0007] To achieve the above-mentioned application purposes, the embodiments of the present application adopt the following technical solutions:

[0008] In one aspect, the present application provides an air purification composition comprising a chlorine dioxide slow-release gel and a Chinese herbal volatile oil slow-release system, wherein the chlorine dioxide slow-release gel comprises the following ingredients in the weight ratio: 2.5-12% (w / v) aqueous oxalic acid 80-95 parts, sodium chlorite 2-8 parts, porous nanomaterial 0.02-0.05 parts, hydroxypropyl methylcellulose K4M 0.03-0.05 parts, and ethyl cellulose 0.04-0.06 parts; and the Chinese herbal volatile oil slow-release system comprises Chinese herbal volatile oil 0.4-0.8 parts and a slow-release matrix material; and the porous nanomaterial has a particle size <0.05 mm.

[0009] The present application utilizes the reaction of oxalic acid and sodium chlorite to generate chlorine dioxide, which can volatilize into the air to exert an effective sterilization effect, and can also undergo redox reactions with various organic and inorganic substances in the air to achieve the purposes of decomposing odors and purifying air. Hydroxypropyl methylcellulose K4M and ethyl cellulose can form a gel after being exposed to water, and the porous nanomaterial forms tiny pores in the gel, so that the chlorine dioxide formed by the aqueous oxalic acid and sodium chlorite can be slowly released. The slow-release matrix material in the Chinese herbal volatile oil slow-release system can adjust the release rate of the Chinese herbal volatile oil, so that the Chinese herbal volatile oil and the chlorine dioxide are slowly released together, achieving the effects of long-term air purification and reducing the incidence of epidemic diseases transmitted through the air. The present application is safe and non-toxic, has a significant purification effect, and can impart a medicinal fragrance to the air, and is suitable for various scenarios such as living rooms, offices, and car interiors.

[0010] The amount of the slow-release matrix material can be selected by a person skilled in the art according to routine experiments, and the slow-release matrix material can be saturated with the Chinese herbal volatile oil.

[0011] Preferably, the chlorine dioxide slow-release gel comprises the following ingredients in the weight ratio: 2.5-10% (w / v) oxalic acid 80-95 parts, sodium chlorite 2-6 parts, porous nanomaterial 0.02-0.04 parts, hydroxypropyl methylcellulose K4M 0.035-0.045 parts, and ethyl cellulose 0.045-0.055 parts.

[0012] Preferably, the chlorine dioxide slow-release gel comprises the following ingredients in the weight ratio: 4-9% (w / v) oxalic acid 80-95 parts, sodium chlorite 3-5 parts, porous nanomaterial 0.03-0.04 parts, hydroxypropyl methylcellulose K4M 0.04 parts, and ethyl cellulose 0.05 parts. The chlorine dioxide slow-release gel in this ratio releases chlorine dioxide for a longer period of time.

[0013] Optionally, the Chinese herbal medicine volatile oil comprises at least one of forsythia suspense volatile oil, honeysuckle volatile oil, pachystachys jothamii volatile oil, citrus reticulata volatile oil, alpinia officinarum volatile oil, atractylodes lancea volatile oil, schizonepeta volatile oil, syzygium aromaticum volatile oil, bupleurum falcatum volatile oil, artemisia argyi volatile oil, houttuynia cordata volatile oil, eucalyptus globulus volatile oil, mentha volatile oil and lemon volatile oil.

[0014] Preferably, the Chinese herbal medicine volatile oil comprises forsythia suspense volatile oil and honeysuckle volatile oil, and the mass ratio of the forsythia suspense volatile oil to the honeysuckle volatile oil is 0.5-2:1.

[0015] The forsythia suspense volatile oil has good antibacterial and antiviral effects, and can inhibit Staphylococcus aureus, Streptococcus pneumoniae, Candida albicans, Shigella boydii, beer yeast and other bacteria and influenza virus, and can effectively inhibit Penicillium chrysogenum and Aspergillus niger and other fungi; the honeysuckle volatile oil has certain inhibitory effect on various pathogenic bacteria such as Staphylococcus aureus, hemolytic streptococcus, Escherichia coli, dysentery bacillus, Vibrio cholerae, Salmonella typhi, paratyphoid bacillus, and has inhibitory and killing effects on Streptococcus pneumoniae, meningococcus, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Shigella dysenteriae, Streptococcus mutans and other bacteria, and can inhibit influenza virus, orphan virus, herpes virus and Leptospira. The combination of the two in the above ratio not only has excellent antibacterial effect, can persistently inhibit the reproduction of harmful microorganisms, and reduce the probability of respiratory diseases such as influenza in the population in the space where the product is used, but also can improve the odor generated after the decomposition of chlorine dioxide, and help to keep the air fresh. Compared with the traditional air disinfection and purification technologies such as activated carbon adsorption, ozone purification, negative oxygen ion technology and electrostatic dust collection technology, the air purification composition obtained by combining forsythia suspense volatile oil and honeysuckle volatile oil with chlorine dioxide has remarkable antibacterial effect, is safe and non-toxic, has pleasant fragrance, and has obvious fresh air effect.

[0016] Preferably, the Chinese herbal medicine volatile oil comprises forsythia suspense volatile oil and honeysuckle volatile oil, and the mass ratio of the forsythia suspense volatile oil to the honeysuckle volatile oil is 1-1.5:1.

[0017] Optionally, the forsythia suspense volatile oil is prepared by using supercritical carbon dioxide extraction method, the extraction pressure is 40-42 MPa, the extraction temperature is 34-36℃, the separation pressure is 6.3-6.5 MPa, and the separation temperature is 27-29℃; and the honeysuckle volatile oil is prepared by using water vapor distillation method, the water amount is 8-10 times the mass of the honeysuckle, and the distillation time is 4-5 h.

[0018] Optionally, the slow-release matrix material is polypropylene, such as YUHMA POLYPRO U050.

[0019] In a second aspect, the present application further provides a preparation method of the air purification composition containing Chinese herbal medicine volatile oil, which specifically comprises the following steps:

[0020] S1, soaking the slow-release matrix material in Chinese herbal medicine volatile oil until saturated, and taking out to obtain the Chinese herbal medicine volatile oil slow-release system;

[0021] S2, mixing the sodium chlorite, porous nanomaterial, hydroxypropyl methyl cellulose K4M and ethyl cellulose, and mixing with the aqueous oxalic acid solution before use to obtain the chlorine dioxide slow-release gel;

[0022] S3, jointly releasing gas from the Chinese herbal medicine volatile oil slow-release system and the chlorine dioxide slow-release gel through a gas release container.

[0023] The slow-release matrix material can be used to slowly release the Chinese herbal medicine volatile oil. The mixed sodium chlorite, porous nanomaterial, hydroxypropyl methyl cellulose K4M and ethyl cellulose are mixed with the aqueous oxalic acid solution before use. The hydroxypropyl methyl cellulose K4M and ethyl cellulose can form a gel in the aqueous oxalic acid solution, and micropores are formed through the porous nanomaterial, so that the chlorine dioxide generated by the reaction of sodium chlorite and oxalic acid is slowly released. The chlorine dioxide and the Chinese herbal medicine volatile oil are slowly released together, which can achieve a lasting air purification effect, and the Chinese herbal medicine volatile oil can also improve the odor of the released gas and mask the unpleasant odor generated by the decomposition of chlorine dioxide.

[0024] In a third aspect, the present application also provides an application of the air purification composition containing Chinese herbal medicine volatile oil in air sterilization.

[0025] The air purification composition can effectively and durably inhibit the reproduction of pathogenic bacteria in the air through the slow release of chlorine dioxide and Chinese herbal medicine volatile oil.

[0026] In a third aspect, the present application also provides an air purification device, which comprises an air purification box and the above-mentioned air purification composition; the air purification box comprises a medicine box and a box cover.

[0027] The medicine box comprises a first box body and a second box body.

[0028] The first box body forms a liquid cavity for containing the aqueous oxalic acid solution.

[0029] The second box body is connected to the top opening of the first box body, the top and bottom of the second box body are both provided with openings, the top opening of the second box body is covered with a sealing film, and the bottom opening of the second box body is provided with a barrier plate. The sealing film, the barrier plate and the second box body form a powder cavity for containing the sodium chlorite, porous nanomaterial, hydroxypropyl methyl cellulose K4M and ethyl cellulose.

[0030] The bottom opening of the second box body is surrounded by a downwardly extending blocking ring, the inner diameter of the blocking ring gradually decreases from top to bottom, and the inner diameter of the lower end of the blocking ring is smaller than the outer diameter of the blocking plate;

[0031] The top of the medicine box is provided with an annular slot opening upward for accommodating the Chinese herbal medicine volatile oil sustained-release system;

[0032] The box cover is used to move relative to the medicine box in the axial direction of the medicine box, and the box cover comprises a connecting body, an adjusting plate and a cover body;

[0033] The connecting body is annular, the bottom of the connecting body is connected with the medicine box, a push rod is arranged in the connecting body, the push rod is used to puncture the sealing film and make the blocking plate fall into the liquid cavity when the box cover moves, and the push rod is connected with the box cover through a connecting frame;

[0034] The adjusting plate is arranged on the top of the connecting body, and a second air hole is arranged on the adjusting plate;

[0035] The cover body is arranged above the adjusting plate, the cover body is rotationally connected with the connecting body, a first air hole is arranged on the cover body, and the first air hole is used to form an air passage with different sizes in cooperation with the second air hole when the cover body rotates.

[0036] Before use, the box cover and the medicine box are two relatively independent individuals, when use is needed, the powder cavity is first punctured by other sharp objects, the puncturing process is as follows: the sharp object is pressed to gradually puncture the sealing film and push the blocking plate to fall into the liquid cavity, at the moment when the blocking plate falls, the sodium chlorite, the porous nanomaterial, the hydroxypropyl methyl cellulose K4M and the ethyl cellulose in the powder cavity also fall into the liquid cavity, and are mixed with the oxalic acid aqueous solution to form a gel (i.e. a chlorine dioxide sustained-release gel), then the box cover is installed on the top of the medicine box, the chlorine dioxide sustained-release gel in the medicine box realizes ventilation with the outside through the first air hole, starts to react to release chlorine dioxide, and realizes air purification. When the blocking plate falls, the air purification box can ensure that the materials in the powder cavity completely enter the liquid cavity, and there is no residual in the powder cavity, so that the materials are fully mixed with the oxalic acid aqueous solution, thereby ensuring that a sufficient amount of chlorine dioxide is generated, and the volatile oil of Chinese herbal medicine is released together, prolonging the use time and optimizing the air purification effect.

[0037] Preferably, the first box body is a transparent member; the connecting frame comprises a plurality of connecting rods, the connecting rods are respectively fixed to the inner wall of the box cover and the push rod, and the connecting rods are radially arranged around the outer periphery of the push rod; the connecting frame further comprises a connecting ring fixed to the inner wall of the box cover, the connecting rods are respectively fixed to the push rod and the connecting ring, the bottom of the connecting ring is provided with a limiting protrusion, and the connecting ring is provided with a third air hole corresponding to the volatile oil sustained-release system of Chinese herbal medicine. BRIEF DESCRIPTION OF DRAWINGS

[0038] Figure 1 A cross-sectional structure schematic view of the air purification box in a split state according to Embodiment 8 of the present application is provided;

[0039] Figure 2 A cross-sectional structure schematic view of the air purification box in an assembled state according to Embodiment 8 of the present application is provided;

[0040] Figure 3 A cross-sectional structure view along the line B-B in Figure 1 ;

[0041] Figure 4 A cross-sectional structure view along the line A-A in Figure 1 (usage state 1);

[0042] Figure 5 A usage state 2 schematic view of Figure 4 ;

[0043] Figure 6 A usage state 3 schematic view of Figure 4 ;

[0044] Figure 7 A top structure schematic view of the cover body adopted by the air purification box in Figure 1 ;

[0045] Figure 8 A top structure schematic view of the second box body adopted by the air purification box in Figure 1 .

[0046] In the figure: 1, box cover; 101, connecting body; 102, adjusting plate; 103, cover body; 104, first air hole; 105, second air hole; 2, medicine box; 201, first box body; 202, second box body; 3, powder cavity; 4, liquid cavity; 5, sealing film; 6, barrier plate; 7, check ring; 8, annular groove; 9, volatile oil sustained-release system of Chinese herbal medicine; 10, push rod; 11, connecting frame; 111, connecting rod; 112, connecting ring; 113, third air hole; 114, limiting protrusion; 12, conical body; 13, reinforcing rib; 14, positioning column; 15, sealing ring. DETAILED DESCRIPTION

[0047] In order to make the objectives, technical solutions and advantages of the present application clearer, the present application will be further described in detail below with specific examples. It should be understood that the specific examples described herein are only used to explain the present application and not to limit the present application.

[0048] The experimental methods used in the following examples are conventional methods in the art unless otherwise specified.

[0049] The forsythia suspensa and honeysuckle used in the following examples all meet the relevant provisions of the Chinese Pharmacopoeia (2015 edition) under the respective medicinal materials in the text.

[0050] The raw materials, reagents and the like used in the following examples are obtained from commercial channels unless otherwise specified.

[0051] Example 1

[0052] The present application provides an air purification composition containing Chinese herbal medicine volatile oil, which comprises a chlorine dioxide slow-release gel and a Chinese herbal medicine volatile oil slow-release system. The chlorine dioxide slow-release gel comprises the following components in parts by weight: 7% (w / v) oxalic acid aqueous solution 85 parts, sodium chlorite 4 parts, diatomite 0.03 parts, hydroxypropyl methylcellulose K4M 0.034 parts and ethyl cellulose 0.05 parts; the Chinese herbal medicine volatile oil slow-release system comprises Chinese herbal medicine volatile oil 0.6 parts and polypropylene, and the Chinese herbal medicine volatile oil is composed of forsythia suspensa volatile oil and honeysuckle volatile oil in a mass ratio of 1.2:1.

[0053] The preparation method of the forsythia suspensa volatile oil is as follows: supercritical carbon dioxide extraction method is adopted, the extraction pressure is 41 MPa, the extraction temperature is 35℃, the separation pressure is 6.4 MPa, and the separation temperature is 28℃.

[0054] The preparation method of the honeysuckle volatile oil is as follows: water vapor distillation method is adopted, the amount of water added is 9 times the mass of the honeysuckle, and the distillation time is 4.5 h.

[0055] The preparation method of the air purification composition is as follows:

[0056] S1, mix the forsythia suspensa volatile oil and the honeysuckle volatile oil, soak the polypropylene in them until saturated absorption, take out, and obtain the Chinese herbal medicine volatile oil slow-release system;

[0057] S2, mix the sodium chlorite, diatomite, hydroxypropyl methylcellulose K4M and ethyl cellulose, and mix with the oxalic acid aqueous solution before use, to obtain the chlorine dioxide slow-release gel;

[0058] S3, release the gas through the gas release container by the Chinese herbal medicine volatile oil slow-release system and the chlorine dioxide slow-release gel.

[0059] Example 2

[0060] The air purification composition containing Chinese herbal medicine volatile oil provided by the embodiment of the present application comprises a chlorine dioxide slow-release gel and a Chinese herbal medicine volatile oil slow-release system, wherein the chlorine dioxide slow-release gel comprises the following components in parts by weight: 80 parts of 4% (w / v) oxalic acid aqueous solution, 3 parts of sodium chlorite, 0.03 parts of diatomite, 0.04 parts of hydroxypropyl methylcellulose K4M and 0.05 parts of ethyl cellulose; the Chinese herbal medicine volatile oil slow-release system comprises 0.5 parts of Chinese herbal medicine volatile oil and polypropylene, and the Chinese herbal medicine volatile oil is composed of forsythia volatile oil and honeysuckle volatile oil at a mass ratio of 1.2:1.

[0061] The preparation method of the forsythia volatile oil, the honeysuckle volatile oil and the air purification composition is the same as that in Embodiment 1.

[0062] Embodiment 3

[0063] The air purification composition containing Chinese herbal medicine volatile oil provided by the embodiment of the present application comprises a chlorine dioxide slow-release gel and a Chinese herbal medicine volatile oil slow-release system, wherein the chlorine dioxide slow-release gel comprises the following components in parts by weight: 95 parts of 9% (w / v) oxalic acid aqueous solution, 5 parts of sodium chlorite, 0.04 parts of diatomite, 0.04 parts of hydroxypropyl methylcellulose K4M and 0.05 parts of ethyl cellulose; the Chinese herbal medicine volatile oil slow-release system comprises 0.7 parts of Chinese herbal medicine volatile oil and polypropylene, and the Chinese herbal medicine volatile oil is composed of forsythia volatile oil and honeysuckle volatile oil at a mass ratio of 1.2:1.

[0064] The preparation method of the forsythia volatile oil, the honeysuckle volatile oil and the air purification composition is the same as that in Embodiment 1.

[0065] Embodiment 4

[0066] The air purification composition containing Chinese herbal medicine volatile oil provided by the embodiment of the present application comprises a chlorine dioxide slow-release gel and a Chinese herbal medicine volatile oil slow-release system, wherein the chlorine dioxide slow-release gel comprises the following components in parts by weight: 80 parts of 4% (w / v) oxalic acid aqueous solution, 3 parts of sodium chlorite, 0.03 parts of diatomite, 0.04 parts of hydroxypropyl methylcellulose K4M and 0.05 parts of ethyl cellulose; the Chinese herbal medicine volatile oil slow-release system comprises 0.5 parts of Chinese herbal medicine volatile oil and polypropylene, and the Chinese herbal medicine volatile oil is composed of forsythia volatile oil and honeysuckle volatile oil at a mass ratio of 1.2:1.

[0067] The preparation method of the forsythia volatile oil, the honeysuckle volatile oil and the air purification composition is the same as that in Embodiment 1.

[0068] Embodiment 5

[0069] The air purification composition containing Chinese herbal medicine volatile oil provided by the embodiment of the present application comprises a chlorine dioxide slow-release gel and a Chinese herbal medicine volatile oil slow-release system, wherein the chlorine dioxide slow-release gel comprises the following components in parts by weight: 10% (w / v) oxalic acid aqueous solution 95 parts, sodium chlorite 6 parts, diatomite 0.04 parts, hydroxypropyl methylcellulose K4M 0.045 parts and ethyl cellulose 0.055 parts; the Chinese herbal medicine volatile oil slow-release system comprises Chinese herbal medicine volatile oil 0.7 parts and a slow-release matrix material, and the Chinese herbal medicine volatile oil is composed of forsythia suspense volatile oil and honeysuckle flower volatile oil at a mass ratio of 1.5:1.

[0070] The preparation method of the forsythia suspense volatile oil, the honeysuckle flower volatile oil and the air purification composition is the same as that in Embodiment 1.

[0071] Embodiment 6

[0072] The air purification composition containing Chinese herbal medicine volatile oil provided by the embodiment of the present application comprises a chlorine dioxide slow-release gel and a Chinese herbal medicine volatile oil slow-release system, wherein the chlorine dioxide slow-release gel comprises the following components in parts by weight: 2.5% (w / v) oxalic acid aqueous solution 80 parts, sodium chlorite 2 parts, diatomite 0.02 parts, hydroxypropyl methylcellulose K4M 0.03 parts and ethyl cellulose 0.04 parts, and the Chinese herbal medicine volatile oil is composed of forsythia suspense volatile oil and honeysuckle flower volatile oil at a mass ratio of 2:1.

[0073] The preparation method of the forsythia suspense volatile oil, the honeysuckle flower volatile oil and the air purification composition is the same as that in Embodiment 1.

[0074] Embodiment 7

[0075] The air purification composition containing Chinese herbal medicine volatile oil provided by the embodiment of the present application comprises a chlorine dioxide slow-release gel and a Chinese herbal medicine volatile oil slow-release system, wherein the chlorine dioxide slow-release gel comprises the following components in parts by weight: 12% (w / v) oxalic acid aqueous solution 95 parts, sodium chlorite 8 parts, diatomite 0.05 parts, hydroxypropyl methylcellulose K4M 0.05 parts and ethyl cellulose 0.06 parts, and the Chinese herbal medicine volatile oil is composed of forsythia suspense volatile oil and honeysuckle flower volatile oil at a mass ratio of 2:1.

[0076] The preparation method of the forsythia suspense volatile oil, the honeysuckle flower volatile oil and the air purification composition is the same as that in Embodiment 1.

[0077] Embodiment 8

[0078] The air purification device provided by the embodiment of the present application comprises an air purification box and the air purification composition containing Chinese herbal medicine volatile oil in Embodiment 1.

[0079] Please refer to Figures 1-8The air purification box comprises a medicine box 2 and a box cover 1; the medicine box 2 comprises a first box body 201 and a second box body 202; the first box body 201 forms a liquid cavity 4 for containing oxalic acid aqueous solution; the second box body 202 is connected to the top opening of the first box body 201, the top and bottom of the second box body 202 are both provided with openings, the top opening of the second box body 202 is covered with a sealing film 5, the bottom opening of the second box body is provided with a blocking plate 6, and the sealing film 5, the blocking plate 6 and the second box body 202 form a powder cavity 3 for containing sodium chlorite, diatomite, hydroxypropyl methyl cellulose K4M and ethyl cellulose;

[0080] A sealing ring 15 is arranged between the second box body 202 and the first box body 201 to play a sealing role and prevent liquid evaporation; the bottom opening of the second box body 202 is surrounded by a downwardly extending blocking ring 7, the inner diameter of the blocking ring 7 gradually decreases from top to bottom, and the inner diameter of the lower end of the blocking ring 7 is smaller than the outer diameter of the blocking plate 6;

[0081] The top of the medicine box 2 is provided with an annular groove 8 opening upward for containing a Chinese herbal medicine volatile oil sustained-release system 9;

[0082] The box cover 1 is used to move relative to the medicine box 2 in the axial direction of the medicine box 2, and the box cover 1 comprises a connecting body 101, an adjusting plate 102 and a cover body 103;

[0083] The connecting body 101 is annular, the bottom of the connecting body 101 is connected to the medicine box 2, a push rod 10 is arranged in the connecting body 101, the push rod 10 is used to puncture the sealing film 5 and make the blocking plate 6 fall into the liquid cavity 4 when the box cover 1 moves, and the push rod 10 is connected to the box cover 1 through a connecting frame 11;

[0084] The adjusting plate 102 is arranged at the top of the connecting body 101, and the adjusting plate 102 is provided with a second air hole 105;

[0085] The cover body 103 is arranged above the adjusting plate 102, the cover body 103 is rotationally connected to the connecting body 101, the cover body 103 is provided with a first air hole 104, and the first air hole 104 is used to form an air passage with different sizes in cooperation with the second air hole 105 when the cover body 103 rotates.

[0086] In the embodiment, the first box body 201 is a transparent member; the connecting frame 11 comprises a plurality of connecting rods 111, the connecting rods 111 are respectively fixed to the push rod 10 and the inner wall of the box cover 1, and the plurality of connecting rods 111 are arranged in a radial manner around the outer periphery of the push rod 10; the connecting frame 11 further comprises a connecting ring 112 fixed to the inner wall of the box cover 1, the connecting rods 111 are respectively fixed to the push rod 10 and the connecting ring 112, the bottom of the connecting ring 112 is provided with a limiting protrusion 114, and the connecting ring 112 is provided with a third air hole 113 corresponding to the Chinese herbal medicine volatile oil sustained-release system 9.

[0087] In the embodiment, the bottom of the connecting rod 111 is provided with a conical body 12, the tip of the conical body 12 is downward and used to pierce the sealing film 5. The connecting rod 111 is further connected with the push rod 10 through a reinforcing rib 13, which prevents the push rod 10 from being skewed by the reaction force, ensures the verticality of the push rod 10, and thus the tip of the push rod 10 is vertically directed to the sealing film 5, which is beneficial to pierce the powder cavity 3. The bottom of the reinforcing rib 13 is lower than the bottom of the limiting protrusion 114, so that when the limiting protrusion 114 contacts the Chinese herbal medicine volatile oil sustained-release system 9, the reinforcing rib 13 directly enters the powder cavity 3, and after the push rod 10 opens the sealing film 5, the reinforcing rib 13 can further expand the opening, which is beneficial to the contact between the mixture and air. The connecting frame 11 is further connected with the adjusting plate 102 through a positioning column 14, which plays a fixing role on the top of the push rod 10.

[0088] The air purification box uses the box cover 1 and the medicine box 2 as two relatively independent individuals before use. When in use, the powder cavity 3 is first pierced by other sharp objects. The piercing process is as follows: press the sharp object to gradually pierce the sealing film 5 and push the blocking plate 6 to fall into the liquid cavity 4. At the moment when the blocking plate 6 falls, the sodium chlorite, porous nanomaterial, hydroxypropyl methyl cellulose K4M and ethyl cellulose in the powder cavity 3 also fall into the liquid cavity 4, and mix with the oxalic acid aqueous solution to form a gel (i.e. chlorine dioxide sustained-release gel). Then the box cover 1 is installed on the top of the medicine box 2. The chlorine dioxide sustained-release gel in the medicine box 2 realizes ventilation with the outside through the first ventilation hole 104, starts to react to release chlorine dioxide, and realizes the purification of air. The air purification box can ensure that the materials in the powder cavity 3 completely enter the liquid cavity 4 when the blocking plate 6 falls, and there is no residue in the powder cavity 3, so that the materials and the oxalic acid aqueous solution are fully mixed, thereby ensuring that a sufficient amount of chlorine dioxide is generated and released together with the Chinese herbal medicine volatile oil, prolonging the use time and optimizing the air purification effect.

[0089] The air purification composition containing Chinese herbal medicine volatile oil in the embodiment can also be replaced by the air purification composition containing Chinese herbal medicine volatile oil in embodiments 2-7.

[0090] Comparative example

[0091] The present comparative example provides a chlorine dioxide sustained-release gel, which has the same components as the chlorine dioxide sustained-release gel in embodiment 1 and is prepared by the same method S2 as in embodiment 1.

[0092] Test example 1

[0093] The present test example investigates the bactericidal effect of the air purification compositions prepared in embodiments 1-7 and the chlorine dioxide sustained-release gel prepared in the comparative example.

[0094] The composition of the nutrient agar medium used in the following experiments is as follows: 10 g of peptone, 3 g of beef extract, 5 g of sodium chloride, 17 g of agar, and 1000 mL of distilled water.

[0095] The composition of the Sabouraud medium is as follows: 10 g of peptone, 20 g of agar, 40 g of glucose, and 1 L of distilled water.

[0096] 1. Experimental method

[0097] The 5th generation nutrient agar medium slant culture (24 h) of the test bacteria was washed with 5 mL of 0.03 mol / L phosphate buffer (hereinafter referred to as PBS) to remove the bacterial mat, and was diluted with the above PBS to prepare a bacterial suspension with a concentration of 5 x 10 4 cfu / mL.

[0098] The air purification compositions prepared in Examples 1 to 7 and the chlorine dioxide slow-release gel prepared in the comparative example were used as test samples. 0.1 mL of the bacterial suspension was applied to the surface of the nutrient agar medium (bacteria) or the surface of the Sabouraud medium (yeast), and four samples were prepared for each test sample, and were placed in a 1 m 3 incubator at 36°C together with 10 g of the test sample. Another 0.1 mL of the bacterial suspension was applied to the surface of the nutrient agar medium and was placed in another 1 m 3 incubator at 36°C as a blank control (four samples were prepared). The viable bacterial colony count was performed at 30 min, 2 h, 6 h, 12 h, 18 h, and 24 h, respectively.

[0099] The test was repeated three times, and the bacteriostatic rate was calculated according to the following formula:

[0100] X = (A - B) / A x 100%

[0101] In the formula, X is the bacteriostatic rate, A is the average number of colonies of the blank control, and B is the average number of colonies of the test sample.

[0102] The average bacteriostatic rate of the air purification compositions prepared in each example and the comparative example at different action times was recorded, and the bacteriostatic logarithmic value was calculated, and the results are shown in Tables 1 to 3.

[0103] Table 1: Bacteriostatic data against Staphylococcus aureus

[0104]

[0105] Table 2: Bacteriostatic data against Escherichia coli

[0106]

[0107] Table 3: Bacteriostatic data against Candida albicans

[0108]

[0109] From the test results of Table 1 to Table 3, it can be seen that the air purification compositions containing Chinese herbal medicine volatile oil obtained in Examples 1 to 7 have high bacteriostatic rates on Staphylococcus aureus, Escherichia coli and Candida albicans in 30 min to 24 h, and the release amount of chlorine dioxide in the sample of Example 1 is lower than that of the comparative example, but the bacteriostatic rate is the same as that of the comparative example, which shows that the forsythia suspense volatile oil and the honeysuckle volatile oil help to improve the bacteriostatic effect.

[0110] Test Example 2

[0111] This test example investigates the toxicological safety of the chlorine dioxide slow-release gel prepared in S2 of the above Example 1.

[0112] 1. Experimental method

[0113] The chlorine dioxide slow-release gel prepared in S2 of Example 1 is used as the sample to be tested.

[0114] (1) Acute oral toxicity test:

[0115] Sample preparation: accurately weigh 5 g ± 0.0025 g of the sample to be tested into a 20 ml volumetric flask, add pure water to the calibration mark, mix well and use, the final concentration is about 250 mg / ml (calculated by the mass of the sample to be tested).

[0116] Experimental method: take 4-week-old Kunming mice, half male and half female, fast overnight before the test, and do not limit the water. The amount of intragastric administration is 5000 mg / kg·bw (calculated by the mass of the sample to be tested), and the intragastric administration volume is 20 ml / kg. After the poisoning, the animal's poisoning performance and the number and time of death are observed, and the autopsy of the dead animals and the animals killed at the end of the observation period is performed, and the abnormal tissues and organs are observed by naked eye, and further histopathological screening is performed. The observation time of symptoms is 14 days.

[0117] (2) Acute inhalation toxicity test

[0118] Experimental method: take 4-week-old Kunming mice, half male and half female, use static poisoning method, put about 0.6 g of the sample to be tested (without preparation, use the original sample to be tested) into the evaporator of the static poisoning cabinet, and make it volatilize, so that the disinfectant concentration required for the experiment is 10000 mg / m 3 , and the animals are exposed to the disinfectant for 2 hours at a time. The symptoms of the animals are observed at any time during the poisoning process, and once a day. The time of appearance and disappearance of poisoning signs and the time of death should be recorded. The observation period is 14 days.

[0119] 2. Experimental results

[0120] The results are shown in Table 4 and Table 5.

[0121] Table 4 Results of acute oral toxicity test

[0122]

[0123] The acute oral toxicity test results show that no toxic symptoms and toxic death were observed in the experimental animals within 14 days, and the body weight of male and female animals showed no abnormalities. At the end of the actual observation, no abnormal changes were observed in the gross autopsy of the test animals. Therefore, under the conditions of this experiment, the LC 50 > 5000 mg / kg·bw, according to the acute toxicity classification standard of Disinfection Technical Specification (2002 edition), the sample of the acute oral toxicity test is practically non-toxic.

[0124] Table 5 Acute inhalation toxicity test results

[0125]

[0126] The acute inhalation toxicity test results show that no toxic symptoms and toxic death were observed in the experimental animals within 14 days, and the body weight of male and female animals showed no abnormalities. At the end of the actual observation, no abnormal changes were observed in the gross autopsy of the test animals. Therefore, under the conditions of this experiment, the LC 50 > 10000 mg / m 3 , according to the acute inhalation toxicity evaluation standard of Disinfection Technical Specification (2002 edition), the sample of the acute inhalation toxicity test is practically non-toxic.

[0127] Test Example 3

[0128] In this test example, the products prepared in Examples 1 to 7 and Comparative Example were subjected to product trial research.

[0129] 1. Experimental purpose: to test the degree of odor preference of consumers for the products prepared in Examples 1 to 7 and Comparative Example.

[0130] 2. Experimental method:

[0131] The air purification compositions containing volatile oils of Chinese herbal medicines of Examples 1 to 7 and the chlorine dioxide slow-release gel of Comparative Example were each made into an air purification device using the gas release box of Example 8, as the test sample of this test example.

[0132] Fifteen women and fifteen men, a total of 30 trial users, were randomly selected to arrange sample trials, and after the trial was completed, they were arranged to fill out the trial research form, and the research results were counted. Among them, 1 point is very dislike, 2 points is dislike, 3 points is general, 4 points is like, and 5 points is very like.

[0133] 3. Experimental data analysis

[0134] The experimental results are shown in Table 6.

[0135] Table 6 consumer trial research results

[0136]

[0137]

[0138] The above research results show that the average score of the trial users on the like degree of the embodiments 1-7 of the present application is the highest, 4.77 points, and feedback that the fragrance is moderate and the fresh air effect is obvious; the average score of the like degree for the comparative examples is 2.93, and feedback that the chlorine dioxide smell is too obvious, and there is a pungent smell when close, although the odor can be eliminated, but the fresh air effect is not as good as that of the embodiments 1-7. The bactericidal and deodorizing effect and the fresh air effect of the products obtained from the embodiments 1-7 are the most obvious, and are most loved by consumers.

[0139] The above only describes the preferred embodiments of the present application and is not intended to limit the present application. Any modification, equivalent replacement or improvement made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. An air purification device, characterized in that, Includes an air purification box and an air purification composition containing volatile oils from traditional Chinese medicine; The air purification box includes a medicine box and a lid; The medicine box includes a first box body and a second box body; The first housing forms a liquid cavity for containing an aqueous solution of oxalic acid; The second box is connected to the top opening of the first box. The second box has openings at both the top and bottom. The top opening of the second box is covered with a sealing film, and the bottom opening of the second box has a barrier plate. The sealing film, the barrier plate, and the second box form a powder cavity for containing sodium chlorite, porous nanomaterials, hydroxypropyl methylcellulose K4M, and ethyl cellulose. The bottom opening of the second box is surrounded by a downwardly extending retaining ring. The inner diameter of the retaining ring gradually decreases from top to bottom, and the inner diameter of the lower end of the retaining ring is smaller than the outer diameter of the barrier plate. The top of the medicine box is provided with an annular groove with an upward opening, which is used to accommodate the slow-release system of volatile oils from traditional Chinese medicine. The lid is used to move relative to the medicine box in the axial direction, and the lid includes a connector, an adjusting plate, and a cover body; The connector is ring-shaped, and its bottom is connected to the medicine box. The connector is provided with a push rod, which is used to puncture the sealing film as the box lid moves, and to cause the barrier plate to fall into the liquid cavity. The push rod is connected to the box lid through a connecting frame. The adjusting plate is located on the top of the connecting body, and the adjusting plate is provided with a second vent hole; Therefore, the cover is placed on top of the adjusting plate, and the cover is rotatably connected to the connecting body. The cover is provided with a first vent hole, which is used to cooperate with the second vent hole to form air passages of different sizes as the cover rotates. The air purification composition containing volatile oils from traditional Chinese medicine comprises a chlorine dioxide slow-release gel and a volatile oil slow-release system from traditional Chinese medicine. The chlorine dioxide slow-release gel comprises the following components in parts by weight: 80-95 parts of 2.5-12% (w / v) oxalic acid aqueous solution, 2-8 parts of sodium chlorite, 0.02-0.05 parts of porous nanomaterials, 0.03-0.05 parts of hydroxypropyl methylcellulose K4M, and 0.04-0.06 parts of ethyl cellulose. The volatile oil slow-release system from traditional Chinese medicine comprises 0.4-0.8 parts of volatile oil from traditional Chinese medicine and a slow-release framework material. The porous nanomaterials have a particle size <0.05 mm. The volatile oils from traditional Chinese medicine include forsythia suspensa volatile oil and honeysuckle volatile oil, with a mass ratio of forsythia suspensa volatile oil to honeysuckle volatile oil of 0.5-2:

1. The slow-release framework material is polypropylene.

2. The air purification device according to claim 1, characterized in that, The chlorine dioxide sustained-release gel comprises the following components in parts by weight: 2.5-10% (w / v) oxalic acid 80-95 parts, sodium chlorite 2-6 parts, porous nanomaterials 0.02-0.04 parts, hydroxypropyl methylcellulose K4M 0.035-0.045 parts, and ethyl cellulose 0.045-0.055 parts.

3. The air purification device according to claim 2, characterized in that, The chlorine dioxide sustained-release gel comprises the following components in parts by weight: 80-95 parts of 4-9% (w / v) oxalic acid, 3-5 parts of sodium chlorite, 0.03-0.04 parts of porous nanomaterials, 0.04 parts of hydroxypropyl methylcellulose K4M, and 0.05 parts of ethyl cellulose.

4. The air purification device according to claim 1, characterized in that, The volatile oils of the Chinese herbal medicines include forsythia volatile oil and honeysuckle volatile oil, and the mass ratio of forsythia volatile oil to honeysuckle volatile oil is 1~1.5:

1.

5. The air purification device according to any one of claims 1 to 4, characterized in that, The preparation method of the air purification composition containing volatile oils from traditional Chinese medicine specifically includes the following steps: S1. Soak the sustained-release framework material in the volatile oil of traditional Chinese medicine until it is saturated with absorption, then remove it to obtain the sustained-release system of the volatile oil of traditional Chinese medicine; S2. The sodium chlorite, porous nanomaterials, hydroxypropyl methylcellulose K4M and ethyl cellulose are mixed, and then mixed with the oxalic acid aqueous solution before use to obtain the chlorine dioxide sustained-release gel. S3. The herbal volatile oil sustained-release system and chlorine dioxide sustained-release gel are released together with the gas through a gas release container.

6. The air purification device according to claim 1, characterized in that, The barrier plate is a silicone sheet; the first box body is a transparent component; and / or The connecting frame includes multiple connecting rods, which are fixedly connected to the inner wall of the push rod and the box cover, respectively, and the multiple connecting rods are arranged radially around the outer periphery of the push rod; the connecting frame also includes a connecting ring fixedly connected to the inner wall of the box cover, the connecting rods are fixedly connected to the push rod and the connecting ring, the bottom of the connecting ring is provided with a limiting protrusion, and the connecting ring is provided with a third vent hole corresponding to the herbal volatile oil slow-release system.

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