Multi-parameter vital signs monitoring device and method

Abstract

The present invention discloses a multi-parameter vital sign monitoring device and method, which are used to detect vital sign parameters, including: a contact portion, which is arc-shaped and corresponds to the head or limbs of a living body; a light source emitting module, which is used to alternately emit detection light to illuminate the surface of the living body; a wide-spectrum photodetector, which is used to receive reflected light reflected when the detection light is projected onto the living body and generate an electrical signal; a multi-channel filter, which is used to filter ambient light when the wide-spectrum photodetector receives reflected light; a main board, which is used to trigger the light source emitting module to emit detection light within a preset signal range, and send the calculation results to an external device in real time via wired or wireless means. The present invention provides a multi-parameter vital sign monitoring device and method, which can obtain multi-parameter vital sign indicators in real time, so that the blue light treatment process has a quantitative basis.

Description

Technical Field

[0001] The present invention relates to the field of detection technology, and in particular to a multi-parameter vital sign monitoring device and method. Background Art

[0002] Neonatal jaundice is a phenomenon in which the skin, mucous membranes and sclera of the whole body turn yellow due to abnormal bilirubin metabolism in the body, resulting in increased bilirubin concentration. It is one of the common diseases in newborns. About 85% of full-term infants and most premature infants will have temporary bilirubin increase in the neonatal period. Clinically, neonatal jaundice is divided into physiological jaundice and pathological jaundice. Pathological jaundice can cause hyperbilirubinemia encephalopathy (kernicterus), and the symptoms are more severe than physiological jaundice, such as anorexia, edema and dyspnea. Because free bilirubin is lipophilic, it will enter the neonatal nerve cells and cause dysfunction of the neonatal nervous system, motor system, hearing system and kidney system. The mortality rate is as high as 80%, and the probability of suffering from sequelae after recovery is 100%. Common sequelae include hyperactivity, hearing loss, dull eyes, developmental problems, etc.

[0003] Newborns with severe jaundice symptoms need blue light therapy. Blue light therapy for neonatal jaundice is generally about 1 to 4 days. Different conditions require different time. The light therapy for severe jaundice is long, generally 48 to 72 hours, and the general light therapy for hyperbilirubinemia is 24 to 48 hours. In general, continuous light exposure should not exceed 4 days. Light therapy for neonatal jaundice is a simple, safe and effective method. It can be divided into single-sided irradiation and double-sided irradiation. It is generally believed that double-sided irradiation is better than single-sided irradiation. Light therapy is divided into continuous irradiation and intermittent irradiation. It is generally believed that continuous irradiation and intermittent irradiation have similar effects, but intermittent irradiation has significantly fewer side effects. Continuous irradiation is generally more than 24 hours. For severe conditions, continuous irradiation can be 48 to 72 hours. During the irradiation process, it is necessary to pay close attention to whether the child has adverse reactions. Intermittent irradiation can be 8 to 12 hours a day, with an interval of 16 to 12 hours; it can also be 6 to 12 hours, with an interval of 2 to 4 hours before irradiation. The irradiation time is determined according to the changes in the irradiation situation. Generally, the total irradiation time does not exceed 4 days.

[0004] At present, hospitals usually use the bilirubin concentration measured by venous blood test or the bilirubin concentration measured by trace blood as the main indicator to determine neonatal jaundice. Among them, venous blood and trace blood tests are invasive tests. The test process requires taking blood from the heel or venous blood of the newborn, and the serum bilirubin concentration is obtained by the diazo reagent method, oxidase method and chemical oxidation method. The advantage of this test method is that it has a high accuracy of about ±5.13μmol / L, but because blood sampling is required, the risk of neonatal infection is increased. Therefore, a non-invasive transcutaneous jaundice meter has emerged, which can quickly detect the bilirubin concentration in the newborn, and has played a significant role in the clinical diagnosis of jaundice.

[0005] However, the above two methods cannot achieve real-time detection of changes in bilirubin concentration in newborns. Clinically, the basis for diagnosing neonatal jaundice and distinguishing whether it is pathological jaundice is: the concentration of bilirubin and the change in bilirubin concentration within a certain period of time. The traditional venous blood test method has high accuracy, but it is not suitable for detecting changes in bilirubin concentration in newborns. The transcutaneous jaundice meter requires medical staff to conduct regular tests at regular intervals, which invisibly increases the workload and does not achieve the effect of real-time monitoring. Especially for infants undergoing blue light therapy, it is impossible to obtain real-time changes in bilirubin content in the infant's body during the treatment process, and it is difficult to make a reasonable judgment on the dose of blue light irradiation, and the effect and safety of the treatment cannot be guaranteed. Summary of the invention

[0006] In view of the above technical problems, the present invention provides a multi-parameter vital signs monitoring device and method, which can obtain the real-time bilirubin content value of the infant's blood during the blue light therapy process, and simultaneously obtain multi-parameter vital signs indicators, so that the blue light therapy process has a quantitative basis to solve the problems of large workload and inability to obtain test results in real time in the existing detection of neonatal jaundice.

[0007] Other features and advantages of the present disclosure will become apparent from the following detailed description, or may be learned in part by the practice of the present disclosure.

[0008] According to one aspect of the present invention, a multi-parameter vital sign monitoring device is disclosed, which is used to detect vital sign parameters, comprising:

[0009] A contact portion, the contact portion is arc-shaped, corresponds to the head or limbs of the living body, and a first hollow area is provided at the center thereof;

[0010] A light source emitting module, the light source emitting module is used to alternately emit detection light, the detection light passes through the first hollow area and then irradiates the surface of the living body;

[0011] A wide-spectrum photoelectric detector is isolated from the light source emission module, and is used to receive the reflected light when the detection light is projected onto the living body, and generate an electrical signal;

[0012] a multi-channel filter, the multi-channel filter being used to filter ambient light when the wide-spectrum photodetector receives the reflected light;

[0013] The mainboard is used to trigger the light source emission module to emit the detection light within a preset signal range, receive and calculate the electrical signal, and send the calculation result to an external device in real time via wired or wireless means.

[0014] Furthermore, the contact portion is made of a soft material, and a detachable silicone pad is provided on its surface.

[0015] Furthermore, the light source emission module and the wide-spectrum photodetector are arranged on the main board, and the light source emission module includes a plurality of LED light sources for emitting the detection light, which are distributed in equal distances around the wide-spectrum photodetector. The detection light emitted by the LED light source includes fluorescence for exciting the surface of a living organism, and / or includes monochromatic light absorbed by the tissue of the living organism.

[0016] Furthermore, an optical path separation component is provided on the main board, and the optical path separation component forms a light output channel corresponding to the detection light emitted by different LED light sources and a light guide channel corresponding to the wide-spectrum photodetector through a partition, and the light guide channel is isolated from the light output channel.

[0017] Furthermore, the outer periphery of the optical path separation component is surrounded by a light-proof cover body, the upper surface of the cover body is hollowed out to form through holes corresponding to the partitions respectively, and the upper surface of the cover body is made of light-transmitting material, wherein the multi-channel filter is arranged at a position in the cover body corresponding to the light guiding channel, or the multi-channel filter is formed on the surface of the wide-spectrum photodetector by coating.

[0018] Furthermore, the device also includes a shell, and the wide-spectrum photodetector, the light source emission module, the multi-channel filter, the main board and the optical path separation assembly are all accommodated in the shell. The lower part of the shell is provided with a second hollow area corresponding to the first hollow area where the contact part is provided. The optical path separation assembly passes through the second hollow area and reaches the first central control area, and the contact part is detachably connected to the lower part of the shell.

[0019] Furthermore, the multi-channel filter is formed on the surface of the broadband photodetector by coating.

[0020] Further, the mainboard includes a main control module, a DAC module, a light source driving module, a signal reading module, and an ADC module. The mainboard is also connected to a power supply module, the main control module is connected to the DAC module and the ADC module, the DAC module is connected to the light source driving module, the light source driving module is connected to the light source transmitting module, the ADC module is connected to the signal reading module, and the signal reading module is connected to the wide-spectrum photoelectric detector, wherein the main control module is used to:

[0021] Control the DAC module to perform a current scanning procedure on the light source driving module, so that the output signal of each LED light source in the light source transmitting module is within a preset signal range, and store the working parameters of each LED light source;

[0022] Sending a trigger signal according to the working parameter, the trigger signal is converted by the DAC module into digital-to-analog form to drive the light source emission module to work through the light source driving module;

[0023] The electrical signal read by the signal reading module is calculated and then transmitted to the external device via wireless / wired, or the read electrical signal is directly transmitted to the external device via wireless / wired.

[0024] Furthermore, the mainboard is also connected to a temperature measuring module, which includes a first temperature sensor and a second temperature sensor respectively arranged in contact with different hollow first copper tubes and second copper tubes, one end of the first copper tube is in contact with the contact portion, and one end of the second copper tube is in contact with the mainboard. After detecting the temperatures of the first copper tube and the second copper tube, the first temperature sensor and the second temperature sensor respectively generate a first temperature signal and a second temperature signal and transmit them to the mainboard. The mainboard adjusts a preset signal range of an output signal of the LED light source according to the second temperature signal, and transmits the first temperature signal to the external device in real time.

[0025] According to a second aspect of the present disclosure, a multi-parameter vital sign monitoring method is provided, which can be applied to the above-mentioned device, and comprises the following steps:

[0026] Placing the contact part on the head or limbs of the person being tested;

[0027] The control mainboard triggers several LED light sources of the light source emission module to alternately emit detection light within a preset signal range to illuminate the surface of the living body;

[0028] Using a wide-spectrum photoelectric detector to receive the reflected light when the detection light is projected onto the living body, and generate a corresponding electrical signal;

[0029] Using a temperature measurement module to measure the temperature of the detected person and the mainboard, and respectively generate a first temperature signal and a second temperature signal, and according to the second temperature signal, adjust the preset signal range of the output signal of the LED light source;

[0030] The mainboard is used to receive and calculate the electrical signal and the temperature signal through a preset algorithm, and the calculation result is sent to an external device in real time through a wired or wireless manner, so that the external device displays the calculation result in real time.

[0031] Furthermore, the method also includes performing absorbance calibration on the LED light source to eliminate the optical path difference, and performing calculation compensation on the light signal intensity of the detection light emitted by the LED light source.

[0032] The technical solution disclosed in this disclosure has the following beneficial effects:

[0033] According to the multi-parameter vital signs monitoring device and method provided by the present invention, medical staff can obtain the real-time bilirubin content value of the infant's blood during the blue light treatment process, and simultaneously obtain vital signs indicators such as body temperature, heart rate, blood oxygen, and respiratory rate, so that the blue light treatment process has a quantitative basis to ensure the effect and safety of the treatment. The present invention uses a combined LED light source as a light source, and effectively reduces the interference of ambient light on the detection by combining a multi-channel filter with a wide-spectrum photodetector, and uses a current scanning program to eliminate the detection consistency error caused by the inconsistency between the light intensity of the LED light source and the central wavelength, thereby realizing a spectral signal acquisition device with a small size, compact optical path structure, and good consistency. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 This is a schematic diagram of the exploded structure of the monitoring device in the embodiment of this specification;

[0035] Figure 2 This is a spectrum correspondence diagram of the multi-channel filter and the wide-spectrum photodetector in the embodiment of this specification;

[0036] Figure 3 This is a schematic diagram of the structure of the optical path separation component in the embodiment of this specification;

[0037] Figure 4 This is a schematic diagram of the structure of the cover body in the embodiment of this specification;

[0038] Figure 5 This is a structural block diagram of the mainboard in the embodiment of this specification;

[0039] Figure 6 It is another exploded structural diagram of the monitoring device in the embodiment of this specification;

[0040] Figure 7 is an exemplary flow chart of the monitoring method in the embodiments of this specification;

[0041] Figure 8 This is an example diagram of a signal spectrum diagram in an embodiment of this specification;

[0042] Fig. 9 This is a flow chart of the absorbance calibration method in the embodiments of this specification.

[0043] Reference numerals:

[0044] 1. contact part; 101. first hollow area; 102. silicone pad;

[0045] 2. Light source emission module;

[0046] 3. Broad spectrum photodetector;

[0047] 4. Multi-channel filter;

[0048] 5. Mainboard; 501. Main control module; 502. DAC module; 503. Light source driving module; 504. Signal reading module; 205. ADC module; 506. Temperature measurement module;

[0049] 6. Light path separation component; 601; partition; 602, light outlet channel; 603, light guide channel;

[0050] 7. Light source lens; 701. Through hole

[0051] 8. Shell; 801. Second hollow area;

[0052] 9. First copper tube;

[0053] 10. Second copper tube;

[0054] 11. A first temperature sensor;

[0055] 12. A second temperature sensor;

[0056] 13. External devices. DETAILED DESCRIPTION

[0057] The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0058] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, which are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0059] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0060] like Figure 1 As shown, the embodiment of this specification provides a multi-parameter vital sign monitoring device for detecting vital sign parameters, including:

[0061] The contact part 1 is arc-shaped, corresponding to the head or limbs of a living body, and a first hollow area 101 is provided at the center thereof;

[0062] Among them, exemplary, both ends of the contact part 1 can be bent inwardly by 10 to 60 degrees, so that it can be stably placed on the head or limbs of the baby, and the first hollow area 101 is provided to detect the skin in contact with the contact part 1.

[0063] A light source emitting module 2, the light source emitting module 2 is used to alternately emit detection light, the detection light passes through the first hollow area 101 and then irradiates the surface of the living body;

[0064] The light source emitting module 2 emits detection light to detect the skin in the first hollow area 101 .

[0065] A wide-spectrum photoelectric detector 3 is isolated from the light source emission module 2, and is used to receive the reflected light when the detection light is projected onto the living body, and generate an electrical signal;

[0066] Among them, the broadband photodetector 3 receives the emitted light from the skin. In order to avoid cross-contamination between the detection light and the emission light, the detection light and the emission light should be isolated, that is, the light source emission module 2 and the broadband photodetector 3 are isolated by opaque material. The opaque material should extend all the way to the skin surface of the person being tested to prevent light pollution. In addition, in other embodiments, the broadband photodetector 3 can be replaced by one of a silicon-based photodiode or a silicon-based CMOS array detector.

[0067] A multi-channel filter 4, wherein the multi-channel filter 4 is used to filter ambient light when the wide-spectrum photodetector 3 receives the reflected light;

[0068] Exemplarily, the multi-channel filter 4 can be a multi-channel multi-channel filter 4, and the number of channels corresponds to the wavelength and number of LED light sources. For example, when there are four LED light sources, the multi-channel filter 4 is a four-channel multi-channel filter 4, and the communication wavelength of each channel corresponds to the center wavelength of each light-emitting LED chip. For example, the spectral bandwidth of each channel is 10nm, and the cut-off depth is greater than OD3. The narrower spectral bandwidth and larger cut-off depth effectively suppress the interference of ambient light on detection. Especially when the baby enters the blue light room for treatment, there is a large amount of ambient light interference. The set multi-channel filter 4 can effectively prevent interference.

[0069] The mainboard 5 is used to trigger the light source emitting module 2 to emit the detection light within a preset signal range, receive and calculate the electrical signal, and send the calculation result to the external device 13 in real time via wired or wireless means.

[0070] Exemplarily, when the mainboard 5 triggers the light source transmitting module 2 to emit detection light within the preset signal range, the LED light source should be lit up in time-sharing mode and the multi-channel split light path multiplexing mode should be adopted. That is, the LED light source only lights up a specific wavelength each time, and the output signal of the wide-spectrum photodetector 3 is collected to obtain an electrical signal. When all LED light sources are off, the ambient light background signal value is collected, and all LED light sources are lit in turn to complete a signal collection cycle. Then, the mainboard 5 calculates the collected electrical signal according to the preset calculation model to calculate the corresponding detection result.

[0071] The mainboard 5 may calculate by controlling some LED light sources to light up alternately, and calculate the electrical signals at the corresponding electrical signals at the corresponding time points to obtain a set of parameters representing the vital signs. Figure 2 The signal spectrum is shown.

[0072] Among them, in the above calculation, the main board 5 can also, after completing the above calculation, control another part of the LED light sources to light up alternately, repeat the above operation, obtain another set of signal spectra containing parameters representing its vital signs, and then take the average value of the two sets of signal spectra.

[0073] In one embodiment, please continue to refer to Figure 1 The contact portion 1 is made of a soft material, and a detachable silicone pad 102 is arranged on its surface.

[0074] Among them, since the subjects in the present disclosure are mostly infants, infants are active and have delicate skin, the provided silicone pad 102 can protect the infant's skin, and the detachable installation of the silicone pad 102 can facilitate the replacement of the silicone pad 102 and prevent the silicone pad 102 from being contaminated by repeated use.

[0075] In one embodiment, please continue to refer to Figure 1 The light source emitting module 2 and the wide-spectrum photodetector 3 are arranged on the main board 5. The light source emitting module 2 includes a plurality of LED light sources for emitting the detection light, which are distributed in an equidistant circle around the wide-spectrum photodetector 3. The detection light emitted by the LED light source includes fluorescence for exciting the surface of a living body, and / or includes monochromatic light absorbed by the tissue of the living body.

[0076] In order to reduce the volume of the device and make it suitable for infants, the light source transmitting module 2 and the light source receiving module are directly installed on the main board 5. At the same time, in order to improve the detection accuracy, the LED light source is arranged around the circumference of the wide-spectrum photodetector 3.

[0077] In one embodiment, see Figure 3 A light path separation component 6 is provided on the main board 5, and the light path separation component 6 is formed with a light output channel 602 corresponding to the detection light emitted by different LED light sources and a light guide channel 603 corresponding to the wide-spectrum photodetector 3 through a partition 601, and the light guide channel 603 is isolated from the light output channel 602.

[0078] It should be explained that the optical path partitioning component 6 is arranged on the main board 5, and can be fixed by pasting, or can be indirectly fixed on the main board 5 by other devices such as the housing 8 and the fixing frame, or can be fixed on the main board 5 by a fixing column. A plurality of opaque partitions 601 should be arranged inside the optical path partitioning component 6, and the partitions 601 divide the space inside the optical path partitioning component 6 into a light guide channel 603 and a light outlet channel 602, so as to achieve isolation between the detection light and the reflected light.

[0079] In the above implementation, as a supplement, please refer to Figure 1and Figure 4 The outer periphery of the optical path separation component 6 is surrounded by a light-proof cover body, and the upper surface of the cover body is hollowed out to form through holes 701 corresponding to the partitions 601 respectively. The upper surface of the cover body is made of a light-transmitting material, wherein the multi-channel filter 4 is arranged at a position in the cover body corresponding to the light guiding channel 603, or the multi-channel filter 4 is formed on the surface of the wide-spectrum photodetector 3 by coating.

[0080] Among them, in order to reduce the volume of the device, the light path separation component 6 is set on the main board 5. For the sake of stability in use, the volume of the light path separation component 6 cannot be too large. Therefore, a cover is set to isolate ambient light in a larger range. In addition, it should be noted that the surface of the cover and the opening of the light path separation component 6 should be flush.

[0081] In addition, in order to facilitate installation, the multi-channel filter 4 can be laid flat on the light guiding channel 603, or the entire hollow surface of the cover body can be the multi-channel filter 4, and a through hole 701 for the detection light to be emitted is provided on the hollow surface, that is, the through hole 701 corresponds to the light output channel 602.

[0082] In addition, in order to reduce the number of assembly steps and improve stability, that is, to prevent the multi-channel filter 4 from loosening during use of the device, the multi-channel filter 4 can be formed on the surface of the wide-spectrum photodetector 3 by chemical coating, that is, coated on the surface of the detector's photosensitive array.

[0083] In one embodiment, please continue to refer to Figure 1 The device also includes a shell 8, the wide-spectrum photodetector 3, the light source emission module 2, the multi-channel filter 4, the main board 5 and the optical path separation component 6 are all accommodated in the shell 8, and the lower part of the shell 8 is provided with a second hollow area 801 corresponding to the first hollow area 101 of the contact part 1, and the optical path separation component 6 reaches the first central control area after passing through the second hollow area 801, and the contact part 1 is detachably connected to the lower part of the shell 8.

[0084] Among them, since the user group of this device is mostly infants, the volume of this device cannot be too large, otherwise it is easy to cause a heavy burden on the infant and affect the detection result. Many components are stored in a flat spheroidal shell 8 to achieve a small volume. The contact part 1 can be connected to the shell 8 by means of a buckle or a bolt, which is convenient for replacing the contact part 1.

[0085] In addition, when the device is installed, the cover body should pass through the second hollow area 801 and the first hollow area 101, and the side of the cover body provided with the through hole 701 (the hollow surface) should be flush with the edge surface of the first hollow area 101 to prevent causing discomfort to the baby.

[0086] In one embodiment, see Figure 5 The main board 5 includes a main control module 501, a DAC module 502, a light source driving module 503, a signal reading module 504, and an ADC module 205. The main board 5 is also connected to a power supply module. The main control module 501 is connected to the DAC module 502 and the ADC module 205. The DAC module 502 is connected to the light source driving module 503. The light source driving module 503 is connected to the light source transmitting module 2. The ADC module 205 is connected to the signal reading module 504. The signal reading module 504 is connected to the wide-spectrum photodetector 3. The main control module 501 is used for:

[0087] Control the DAC module 502 to perform a current scanning procedure on the light source driving module 503, so that the output signal of each LED light source in the light source transmitting module 2 is within a preset signal range, and store the working parameters of each LED light source;

[0088] A trigger signal is sent out according to the working parameter, and the trigger signal is converted by the DAC module 502 into digital-to-analog signals to drive the light source emitting module 2 to work through the light source driving module 503;

[0089] The electrical signal read by the signal reading module 504 is calculated and then transmitted to the external device 13 via wireless / wired, or the read electrical signal is directly transmitted to the external device 13 via wireless / wired.

[0090] Among them, the main control chip can be an MCU chip, and the MCU chip transmits the calculation results to the external device 13 in real time by connecting to the wired interface module or the wireless connection module. By way of example, in order to reduce the cost and the volume of the mainboard 5, the main control chip can also be a Bluetooth SOC chip. The wireless connection of the device can be directly realized through the Bluetooth SOC chip. Due to the mobility of the user group, the practicality of the device can be greatly improved after reducing the constraints of cables. The external device 13 can be any electronic device with Bluetooth wireless function, such as a mobile phone, a tablet, a computer, etc.

[0091] When the mainboard 5 is triggered to work and calculate, firstly, due to the natural limitation of the manufacturing process, there are differences in the luminous power between individuals of the same model of LED light source, which must be eliminated in the application of using light intensity as the detection signal; secondly, due to the difference in human tissue parameters, the absorption and scattering coefficients of detection light of different wavelengths in the human body are quite different. In order to eliminate the above differences, without changing the parameters of the signal reading module 504, the best detection signal value can be achieved by designing a program. Specifically, firstly, an optimal signal range is preset for a specific LED light source, and this signal range is determined by the low point threshold LED1_LOW and the high point threshold LED1_HIGH, and each LED light source corresponds to a different low point threshold and high point threshold; after the device contacts the human body, the Bluetooth SOC chip controls the DAC module 502 to perform a precise current scanning program, so that the output signal of each LED light source enters the set threshold range, and determines the corresponding working parameters at this time; the LED light source is driven to work according to the determined working parameters, and then the wide spectrum photodetector 3 collects the signal to obtain the desired electrical signal.

[0092] Through the above method, the detection amplitude is standardized, and there is no need to calibrate the hardware and adjust the parameters. Combined with the preset detection algorithm, accurate real-time detection can be achieved.

[0093] In one embodiment, please continue to refer to Figure 5 and see Figure 6 The mainboard 5 is also connected to a temperature measuring module 506, which includes a first temperature sensor 11 and a second temperature sensor 12 respectively arranged in contact with different hollow first copper tubes 9 and second copper tubes 10, one end of the first copper tube 9 is in contact with the contact portion 1, and one end of the second copper tube 10 is in contact with the mainboard 5. After detecting the temperatures of the first copper tube 9 and the second copper tube 10, the first temperature sensor 11 and the second temperature sensor 12 respectively generate a first temperature signal and a second temperature signal and transmit them to the mainboard 5. The mainboard 5 adjusts the preset signal range of the output signal of the LED light source according to the second temperature signal, and transmits the first temperature signal to the external device 13 in real time.

[0094] Among them, the first temperature sensor 11 and the second temperature sensor 12 can be thermistors. In terms of circuit connection, the negative pole of the LED light source is connected to an electrode of the second temperature sensor 12, and continuous large-area copper plating is used on the main board 5 to ensure reliable and rapid heat conduction. After the second temperature signal is collected by the Bluetooth SOC, the constant current optical power change of the LED light source can be compensated according to the second temperature signal.

[0095] According to a multi-parameter vital signs monitoring device provided by the above embodiment, medical staff can obtain the real-time bilirubin content value of the infant's blood during the blue light treatment process, and simultaneously obtain vital signs indicators such as body temperature, heart rate, blood oxygen, and respiratory rate, so that the blue light treatment process has a quantitative basis to ensure the effect and safety of the treatment. The present invention uses a combined LED light source as a light source, and effectively reduces the interference of ambient light on the detection by combining a multi-channel filter 4 with a wide-spectrum photodetector 3, and uses a current scanning program to eliminate the detection consistency error caused by the inconsistency between the light intensity of the LED light source and the central wavelength, thereby realizing a spectral signal acquisition device with a small size, compact optical path structure, and good consistency.

[0096] Based on the same idea, the exemplary embodiment of the present disclosure also provides a multi-parameter vital sign monitoring method, as shown in FIG. 7 , the method comprises the following steps S1 to S5:

[0097] In step S1: placing the contact part on the head or limbs of the person being tested;

[0098] In step S2: the control mainboard triggers several LED light sources of the light source emission module to alternately emit detection light within a preset signal range to illuminate the surface of the living body;

[0099] In step S3: using a wide-spectrum photoelectric detector to receive the reflected light when the detection light is projected onto the living body, and generating a corresponding electrical signal;

[0100] In step S4: using the temperature measurement module to measure the temperature of the detected person and the mainboard, and respectively generate a first temperature signal and a second temperature signal, and according to the second temperature signal, adjust the preset signal range of the output signal of the LED light source;

[0101] In step S5: the mainboard is used to receive and calculate the electrical signal and the temperature signal through a preset algorithm, and the calculation result is sent to an external device in real time via wired or wireless means, so that the external device displays the calculation result in real time.

[0102] In one embodiment, a calculation method and algorithm for a vital sign parameter is provided, as follows:

[0103] The number of LED light sources is set to four by way of example, and the wavelengths thereof are 650nm, 850nm, 550nm, and 460nm, respectively, wherein:

[0104] By controlling the 650nm LED light source and the 850nm LED light source to light up alternately, and passing the respective electrical signals of the mainboard at the corresponding time points, the signal acquisition frequency is between 1K-2K, and the acquisition time is between 10-20s. A set of signal spectra containing heart rate changes is obtained, such as Figure 3 As shown:

[0105] Calculate blood oxygen and heart rate from the above signals:

[0106] Blood oxygen calculation method:

[0107]

[0108]

[0109] Wherein AC_650nm is the difference between the peak and valley of the signal of the 650nm LED light source, specifically, the arithmetic mean of each peak and valley signal difference; DC_650nm is the average value of the signal intensity of the 650nm LED light source;

[0110] Wherein AC_850nm is the difference between the peak and valley of the signal of the 850nm LED light source, specifically, the arithmetic mean of each peak and valley signal difference; DC_850nm is the average value of the signal intensity of LED2;

[0111] ε-hb_650nm is the absorption coefficient of deoxyhemoglobin at 650nm, ε-hbo2_650nm is the absorption coefficient of oxygen and hemoglobin at 650nm;

[0112] ε-hb_850nm is the absorption coefficient of deoxyhemoglobin at 850nm, ε-hbo2_850nm is the absorption coefficient of oxygen and hemoglobin at 850nm;

[0113] A is the correction coefficient, which is obtained through a finite number of experiments.

[0114] How to calculate heart rate:

[0115] By performing the same data collection on a 550nm LED light source, the waveform signal of this wavelength can be obtained, and then the waveform period can be calculated to obtain the heart rate value.

[0116] Calculation method of jaundice value:

[0117] By collecting data for the 460nm LED light source, the same set of signal values ​​is obtained, and the average value of the set of signal values ​​is calculated. Correspondingly, the average value of the 550nm LED light source signal is calculated.

[0118] Then, the jaundice value is calculated by the following formula.

[0119]

[0120] Where I_550nm is the average signal intensity of the LED light source of 550nm; where I_460nm is the average signal intensity of the LED light source of 460nm; E, α, and D are correction coefficients obtained through a limited number of experiments.

[0121] The above method can be used to quickly and stably obtain multiple human health parameters; the sensor is small in size and can be attached to the human body for use.

[0122] In one embodiment, the multi-parameter vital sign monitoring method further includes: performing absorbance calibration on the LED light source to eliminate optical path differences, and performing computational compensation on the light signal intensity of the detection light emitted by the LED light source.

[0123] In this embodiment, a method for compensating temperature variation of constant current optical power of an LED light source is provided as follows:

[0124] Since the luminous efficiency of LED chips is greatly affected by temperature, in applications where light intensity is used as a detection signal, such as the detection of jaundice value in this case, it is necessary to ensure that the light power of the LED light source remains stable during the signal acquisition cycle. However, in actual applications, the continuously luminous LED chip also generates a large amount of heat, and the junction temperature of the LED continues to rise, causing the light emission efficiency to continue to decrease. Here, a relative value method based on experimental data is proposed to perform temperature compensation on the constant current luminous power of the LED. The specific method steps include S201 to S205:

[0125] In step S201, a specific white board (made of polytetrafluoroethylene) is fixed in front of the light source in the device embodiment.

[0126] In step S202, the device in the above embodiment is placed in a constant temperature control box with adjustable temperature.

[0127] In step S203, the mainboard controls to light up a certain LED light source with a very short pulse (0-10ms), and at the same time controls to collect the output signal of the wide spectrum detector and the output signal of the second temperature sensor; the above process is repeated with a period of seconds.

[0128] In step S204, the temperature of the thermostat is adjusted to perform a temperature scan from 0 to 50 degrees Celsius at an interval of 5 degrees Celsius.

[0129] In step S205, the above process is repeated to collect data of other LED light sources.

[0130] According to the experimental data, the following temperature compensation method is obtained:

[0131]

[0132] V act It is the current directly collected LED light source signal voltage value, and the unit of voltage is millivolt (mv).

[0133] V cal is the corrected LED signal voltage value.

[0134] K is 100 times the relative change in voltage relative to 25 degrees Celsius.

[0135] According to the formula K = b0 + b1T + b2T 2 +b3T 3 , T is 100 times the actual temperature.

[0136] Taking a 469nm LED light source as an example, the following coefficients are obtained by performing a third-order polynomial fitting according to formula 1 based on the data obtained in steps S203 to S204:

[0137] b0=4.48746;

[0138] b1=-0.00292;

[0139] b2=4.57625E-7;

[0140] b3 = -3.91797E-12;

[0141] Based on the above coefficients, the ratio of temperature compensation for the constant current luminous power of the LED can be obtained.

[0142] As a supplement, the absorbance calibration of the LED light source can also be performed. Due to the optical path differences caused by the manufacturing tolerances and assembly errors of the LED light source and the light source lens, multi-channel filter, optical path separation component, and wide-spectrum detector in the device embodiment, the absorbance of each LED light source is calibrated by the following method to eliminate the inter-unit difference and improve the precision of the device. Specifically, a calibration method flow chart is provided through experimental data, as shown in FIG. Fig. 9 shown.

[0143] It is worth noting that in the absorbance calibration method for eliminating the optical path difference of the LED light source in the above embodiment, a two-point linear calibration method is used to obtain the standard absorbance curve of the specific LED, and it is ensured that the light source driver module has a default output current of 20ma at an ambient temperature of 25°C.

[0144] It is worth noting that in Fig. 9 In the embodiment, ADC corresponds to the ADC module in the device implementation, and the light source driver corresponds to the light source driver module.

[0145] The specific details of the above method have been described in detail in the implementation method of the device part. The undisclosed details can be found in the implementation method of the device part, so they will not be repeated here.

[0146] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit them; although the present invention is described in detail with reference to the above embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the above embodiments, or replace some or all of the technical features therein by equivalents; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present invention. In addition, those skilled in the art can understand that although some embodiments described herein include certain features included in other embodiments instead of other features, the combination of features of different embodiments means that they are within the scope of the present invention and form different embodiments. For example, in the above claims, any one of the embodiments claimed for protection can be used in any combination. The information disclosed in this background technology section is only intended to deepen the understanding of the overall background technology of the present invention, and should not be regarded as admitting or suggesting in any form that the information constitutes prior art known to those skilled in the art.

Claims

1. A multi-parameter vital signs monitoring device for detecting vital signs parameters, characterized in that: include: A contact portion, the contact portion is arc-shaped, corresponds to the head or limbs of the living body, and a first hollow area is provided at the center thereof; A light source emitting module, the light source emitting module is used to alternately emit detection light, the detection light passes through the first hollow area and then irradiates the surface of the living body; A wide-spectrum photoelectric detector is isolated from the light source emission module, and is used to receive the reflected light when the detection light is projected onto the living body and generate an electrical signal, and is used to collect the ambient light background signal value when all LED light sources are turned off; a multi-channel filter, the multi-channel filter being used to filter ambient light when the wide-spectrum photodetector receives the reflected light, and being used to separate an optical signal of a preset wavelength from the reflected light; A mainboard, the mainboard is used to trigger the light source emission module to emit the detection light within a preset signal range, receive and calculate the electrical signal, and send the calculation result to an external device in real time via a wired or wireless manner; The light source emission module and the wide-spectrum photoelectric detector are arranged on the main board. The light source emission module includes a plurality of LED light sources for emitting the detection light and distributed in an equidistant circle around the wide-spectrum photoelectric detector. The detection light emitted by the LED light source includes fluorescence for stimulating the surface of a living body and / or includes monochromatic light absorbed by the tissue of the living body. An optical path separation component is arranged on the main board. The optical path separation component forms a light output channel corresponding to the detection light emitted by different LED light sources and a light guiding channel corresponding to the wide-spectrum photoelectric detector through a partition. The light guiding channel and the light output channel are isolated from each other.

2. The multi-parameter vital signs monitoring device according to claim 1, characterized in that: The contact part is made of soft material, and a detachable silicone pad is arranged on its surface.

3. The multi-parameter vital signs monitoring device according to claim 1, characterized in that: The outer periphery of the optical path separation component is surrounded by a light-proof cover body, the upper surface of the cover body is hollowed out to form through holes corresponding to the partitions respectively, and the upper surface of the cover body is made of light-transmitting material, wherein the multi-channel filter is arranged at a position in the cover body corresponding to the light guiding channel, or the multi-channel filter is formed on the surface of the wide-spectrum photodetector by coating.

4. The multi-parameter vital signs monitoring device according to claim 1, characterized in that: The device also includes a shell, and the wide-spectrum photodetector, the light source emission module, the multi-channel filter, the main board and the optical path separation component are all accommodated in the shell. The lower part of the shell is provided with a second hollow area corresponding to the first hollow area where the contact part is provided. The optical path separation component reaches the first hollow area after passing through the second hollow area, and the contact part is detachably connected to the lower part of the shell.

5. The multi-parameter vital signs monitoring device according to claim 1, characterized in that: The mainboard includes a main control module, a DAC module, a light source driving module, a signal reading module, and an ADC module. The mainboard is also connected to a power supply module. The main control module is connected to the DAC module and the ADC module. The DAC module is connected to the light source driving module. The light source driving module is connected to the light source transmitting module. The ADC module is connected to the signal reading module. The signal reading module is connected to the wide-spectrum photoelectric detector. The main control module is used for: Control the DAC module to perform a current scanning procedure on the light source driving module, so that the output signal of each LED light source in the light source transmitting module is within a preset signal range, and store the working parameters of each LED light source; Sending a trigger signal according to the working parameter, the trigger signal is converted by the DAC module into digital-to-analog form to drive the light source emission module to work through the light source driving module; The electrical signal read by the signal reading module is calculated and then transmitted to the external device via wireless / wired, or the read electrical signal is directly transmitted to the external device via wireless / wired.

6. The multi-parameter vital signs monitoring device according to claim 5, characterized in that: The main board is also connected to a temperature measuring module, which includes a first temperature sensor and a second temperature sensor respectively arranged in contact with different hollow first copper tubes and second copper tubes, one end of the first copper tube is in contact with the contact portion, and one end of the second copper tube is in contact with the main board. After detecting the temperatures of the first copper tube and the second copper tube, the first temperature sensor and the second temperature sensor respectively generate a first temperature signal and a second temperature signal and transmit them to the main board. The main board adjusts a preset signal range of an output signal of the LED light source according to the second temperature signal, and transmits the first temperature signal to the external device in real time.

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