Sample delivery device and gynecological discharge detection device

Abstract

A sample conveying device and a gynecological secretion detection device, wherein the detection device comprises a sample inlet mechanism, a sample reaction mechanism, a conveying mechanism and a detection mechanism, a sampling position and a reaction position are defined along the movement track of the sample inlet mechanism, a sample adding position and a detection position are defined along the conveying direction of the conveying mechanism, the sampling position, the reaction position and the sample adding position are arranged in sequence in a first direction, and the sample adding position and the detection position are arranged in sequence along the conveying direction of the conveying mechanism. Through the setting of the positions of the mechanisms and functional positions of the device, the reasonable layout of each mechanism of the whole device is realized, the dependency and interference between the mechanisms are reduced, and conditions for improving the detection efficiency of the device are created.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical detection, in particular to a sample conveying device and a gynecological secretion detection device. BACKGROUND

[0002] Gynecological secretion (also known as vaginal secretion) is a liquid secreted by the female reproductive system, commonly known as "leukorrhea". The detection and analysis of gynecological secretion is a routine detection item in clinical medicine, and the detection and analysis results of gynecological secretion can provide a basis for the diagnosis of gynecological diseases. For the detection of gynecological secretion, the traditional method mainly relies on manual operation to complete the sample pretreatment task (such as sample addition, reagent addition, elution mixing, etc.) and sample detection task (such as physical detection, chemical detection, and analysis of formed elements of the sample), which is not only tedious and inefficient, but also mostly subjective to the human eye, which can easily lead to misdiagnosis and other problems.

[0003] With the development of science and technology, some automatic detection instruments have appeared on the market. Such instruments mainly complete the operation items (such as sample addition, reagent addition, elution mixing, and detection) required for the detection of a sample, and use a linear conveying device to sequentially convey the sample to be detected to the sample addition position, the reagent addition position, the elution mixing position, and the detection position in the order of the operation items. Then, the relevant execution mechanisms complete the processing of the sample to be detected at the corresponding position area, thereby relying on the instrument to automatically complete part or all of the operation items, greatly improving the detection efficiency and quality. However, the existing automatic detection instruments still have the following defects: the operation execution mechanisms are arranged in a linear structure along the linear conveying device, which is an unreasonable layout, resulting in a large size of the instrument and relatively low detection efficiency. SUMMARY

[0004] The technical problem to be solved by the present application is to provide a sample conveying device and a gynecological secretion detection device, aiming to solve the problem of low detection efficiency of gynecological secretion samples.

[0005] According to a first aspect, a sample conveying device is provided in an embodiment, comprising:

[0006] a sample introduction mechanism controllably moving in a first direction, a plurality of functional positions being defined along the movement trajectory of the sample introduction mechanism, the plurality of functional positions comprising a sampling position and a reaction position;

[0007] a sample reaction mechanism arranged at the reaction position, so that the sample introduction mechanism sucks the sample to be detected at the sampling position, and conveys the sample to be detected to the reaction position and adds it to the sample reaction mechanism in the first direction;

[0008] The conveying mechanism has a sample dispensing position defined along its conveying direction. The sampling position, reaction position, and sample dispensing position are arranged sequentially in the first direction so that the sample injection mechanism conveys the sample to be tested to the sample dispensing position and adds it to the conveying mechanism in the first direction.

[0009] According to the second aspect, a gynecological secretion detection device includes:

[0010] The sample introduction mechanism is controllably movable along a first direction, and multiple functional positions are defined along the movement trajectory of the sample introduction mechanism, including sampling positions and reaction positions;

[0011] A sample reaction mechanism is disposed on a reaction position, such that the sample introduction mechanism picks up the sample to be tested at the sampling position, conveys the sample to be tested to the reaction position in the first direction, and adds it to the sample reaction mechanism.

[0012] The conveying mechanism has a sample dispensing position and a detection position defined along the conveying direction of the conveying mechanism. The sampling position, reaction position and sample dispensing position are arranged sequentially in the first direction. The sample dispensing position and the detection position are arranged sequentially along the conveying direction of the conveying mechanism, so that after the sample injection mechanism conveys the sample to be tested to the sample dispensing position and adds it to the conveying mechanism in the first direction, the conveying mechanism conveys the sample to be tested from the sample dispensing position to the detection position.

[0013] The testing institution is used to perform gynecological tests on the sample to be tested when the transport mechanism transports the sample to be tested to the testing position.

[0014] The gynecological secretion detection device according to the above embodiment includes a sample injection mechanism, a sample reaction mechanism, a transport mechanism, and a detection mechanism. A sampling position and a reaction position are defined along the movement trajectory of the sample injection mechanism, and a sample application position and a detection position are defined along the transport direction of the transport mechanism. The sampling position, reaction position, and sample application position are arranged sequentially in a first direction, and the sample application position and detection position are arranged sequentially along the transport direction of the transport mechanism. By setting the positions of each mechanism and functional position of the device, a reasonable layout of all mechanisms in the entire device is achieved, reducing the dependence and interference between mechanisms, and creating conditions for improving the detection efficiency of the device. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the isometric structure of the detection device in one embodiment;

[0016] Figure 2 for Figure 1 A top view of the detection device;

[0017] Figure 3 for Figure 1 Axonometric structural diagram of the rotary conveyor mechanism;

[0018] Figure 4 For Figure 3 The functional bit distribution identification chart of the detection device in the middle;

[0019] Figure 5 For Figure 1 The shaft structure schematic diagram of the card bin mechanism in the middle;

[0020] Figure 6 For Figure 1 The shaft structure schematic diagram of the sample injection mechanism in the middle;

[0021] Figure 7 For Figure 1 The shaft structure schematic diagram of the mirror detection mechanism in the middle;

[0022] Figure 8 For Figure 7 The structural exploded schematic diagram of the mirror detection mechanism in the middle;

[0023] Figure 9 For Figure 1 The shaft structure schematic diagram of the photographing mechanism in the middle;

[0024] Figure 10 For Figure 1 The shaft structure schematic diagram of the sample delivery part in the middle (1);

[0025] Figure 11 For Figure 1 The shaft structure schematic diagram of the sample delivery part in the middle (2);

[0026] Figure 12 For Figure 10 And Figure 11 The shaft structure schematic diagram of the elution mechanism in the middle;

[0027] Figure 13 For Figure 10 And Figure 11 The shaft structure schematic diagram of the compression assembly in the middle;

[0028] Figure 14 For Figure 10 And Figure 11 The top view sectional structure schematic diagram of the compression assembly in the middle;

[0029] Figure 15 The shaft structure schematic diagram of the sample reaction mechanism in the middle of an embodiment;

[0030] Figure 16 For Figure 15 The structural exploded schematic diagram of the sample reaction mechanism in the middle;

[0031] Figure 17 For Figure 1 The system architecture reference schematic diagram of the detection device in the middle

[0032] Figure 18 For Figure 1 The detection process schematic diagram of the detection device in the embodiment;

[0033] Figure 19 For Figure 1 The detection method flow chart of the detection device in the embodiment;

[0034] Figure 20 For Figure 19 The method flow chart of the sample adding step in the embodiment;

[0035] Figure 21 For Figure 19 The method flow chart of the gynecological item detection step in the embodiment;

[0036] Figure 22 For Figure 1 The scheduling method flow chart of the carousel conveying mechanism in the embodiment. DETAILED DESCRIPTION

[0037] The gynecological item detection described in the present application includes but is not limited to two types of projects of microscopic examination (also known as microscopic examination) and dry chemical detection for gynecological secretions (i.e. vaginal secretions, commonly known as "leukorrhea"). The microscopic examination project mainly detects the formed elements in the gynecological secretions (such as mold, hyphae, clue cells, trichomonas, epithelial cells, white blood cells, bacilli, cocci, small round epithelial cells, red blood cells, etc.); the dry chemical detection mainly detects the reaction structure of the gynecological secretions, including sialidase (SNA), β-N-acetylglucosaminidase (NAG), leukocyte esterase activity (LE), proline aminopeptidase (PIP), pH value, hydrogen peroxide, etc.

[0038] The gynecological secretion detection device provided by the present application completes sample preparation, detection card adding, detection card transfer, sample adding, sample detection, and card discarding in one detection cycle. The detection cycle refers to the operation required to complete the detection of one sample. Each sample corresponds to a detection card. When the sample is detected, the detection card corresponding to the sample is placed in a predetermined position of the carousel conveying mechanism, and then the sample is added to the detection card. Subsequently, the detection card with the added sample is detected, and finally the detection card after completion of the detection is discarded and recycled.

[0039] The first direction and the second direction described in the present application refer to two different directions naturally formed by the device in the environmental space. The first direction and the second direction can be orthogonal directions or intersecting directions. In the case of orthogonal directions, taking a spatial orthogonal coordinate system as an example, if the first direction is the Y-axis direction, the second direction can refer to the X-axis direction. In this case, the third direction described in the present application can refer to the Z-axis direction.

[0040] The application will be described in further detail below with reference to the drawings.

[0041] Please refer to Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 6 , Figure 15 and Figure 16 , one embodiment provides a sample delivery device, comprising a sample feeding mechanism 300 for conveying a sample, a sample reaction mechanism 1400 for reaction processing of the sample, and a delivery mechanism for delivering the sample to a detection position for detection; wherein:

[0042] Please refer to Figure 4 and Figure 6 , the sample feeding mechanism 300 comprises a support arm 301, a third direction walking driving assembly 302 and a first direction walking driving assembly 303 electrically connected with the controller 1300 respectively, and a sampling assembly 304 installed on the support arm 301 through the third direction walking driving assembly 302 and the first direction walking driving assembly 303; wherein, the first direction walking driving assembly 303 drives the sampling assembly 304 to move in the first direction, and a plurality of functional positions are defined along the movement track of the sample feeding mechanism 300 in the first direction, and the plurality of functional positions comprise a sampling position g and a reaction position n. The sample reaction mechanism 1400 is arranged at the reaction position n, when the first direction walking driving assembly 303 drives the sampling assembly 304 to move to the sampling position g, the sampling assembly 304 sucks the sample to be detected, and then conveys the sample to be detected to the reaction position n, adds the sample to be detected to the sample reaction mechanism 1400, so as to use the sample reaction mechanism 1400 to process the sample such as dilution, staining, turbidity detection and the like. At the same time, a sample adding position b is defined along the delivery direction of the delivery mechanism, wherein the sampling position g, the reaction position n and the sample adding position b are arranged in sequence in the first direction; after the sampling assembly 304 sucks the sample to be detected which has completed the reaction processing from the sample reaction mechanism 1400, the first direction walking driving assembly 302 drives the sampling assembly 304 to the sample adding position b, so as to add the sample to be detected to the delivery mechanism. In this process, by driving the sampling assembly 304 through the third direction walking driving assembly 302, the sampling assembly 304 can complete the action of sucking the sample to be detected at the sampling position g, complete the actions of sucking and adding the sample to be detected at the reaction position n, and complete the action of adding the sample to be detected at the sample adding position b.

[0043] By arranging the sampling position g, the reaction position n and the adding position b in sequence along one direction, the sampling mechanism 300 can perform the actions of sample suctioning, sample adding, sample suctioning and sample adding in sequence for one sample to be detected when the sampling mechanism 300 moves in the first direction in one direction. For multiple samples to be detected, the sampling mechanism 300 can continuously add the multiple samples to be detected to the conveying mechanism by reciprocating in the first direction. Based on this, the automatic conveying process of the samples to be detected is realized by the structure of the conveying device and the layout of the functional positions.

[0044] The sample conveying device provided by one embodiment further comprises a cleaning mechanism, and the functional positions further comprise a cleaning position p. The sampling position g, the cleaning position p, the reaction position n and the adding position b are arranged in sequence in the first direction. The cleaning mechanism is arranged at the cleaning position p, so that the sampling mechanism 300 (in particular, the sampling assembly 304) is cleaned after adding the sample to be detected to the cleaning mechanism. For one sample, the sampling mechanism 300 continuously conveys different samples in the order of the sampling position g, the reaction position n, the adding position b, the cleaning position p and the sampling position g. In this process, the cleaning mechanism at the cleaning position p cleans the sampling mechanism 300 after conveying each sample, so as to remove the residual samples, reagents and the like on the sampling mechanism 300, and effectively avoid cross contamination between the samples. In this embodiment, the cleaning mechanism mainly comprises a cleaning tank for containing cleaning liquid and other conventional components.

[0045] One embodiment, please refer to Figure 1 、 Figure 15 and Figure 16 The sample reaction mechanism 1400 comprises a support frame 1410, a reaction container 1420, a turbidity detector 1430 and a reagent adding pipe 1440. Wherein:

[0046] The support frame 1410 is mainly used for providing structural assembly space for the reaction container 1420, the turbidity detector 1430 and the reagent adding pipe 1440, so that the reaction container 1420, the turbidity detector 1430 and the reagent adding pipe 1440 can be structurally integrated to form a complete sample reaction component. At the same time, the support frame 1410 can also assemble the entire sample reaction mechanism 1400 in the form of an independent individual in the existing sample analysis and detection device, so as to create favorable conditions for the structural optimization and functional integration of such devices

[0047] The reaction container 1420 is mainly used for containing the sample to be detected and the reagent added due to the reaction, detection and operation of the sample, and is installed on the support frame 1410 and forms a containing space including the cup mouth area 1421 and the detection area 1422 which are communicated with each other. The maximum cross-sectional area of the detection area 1422 in the communication direction is less than or equal to the minimum cross-sectional area of the cup mouth area 1421, so as to effectively prevent the sample to be detected and the reagent from splashing out of the reaction container 1420 when the sample to be detected and the reagent are contained from the cup mouth area 1421 to the detection area 1422. In an embodiment, the reaction container 1420 can also use the existing reaction cup, sample test tube and the like.

[0048] The turbidity detector 1430 is mainly used for detecting the turbidity of the sample to be detected contained in the detection area 1422, is installed on the support frame 1410 and located at the outer peripheral side of the reaction container 1420 (specifically the detection area 1422). In this embodiment, the turbidity detector 1430 mainly consists of a detection light emitting member 1431 and a detection light receiving member 1432, the emission end of the detection light emitting member 1431 is oppositely arranged with the receiving end of the detection light receiving member 1432, and the reaction container 1420 (specifically the detection area 1422) is located between the detection light emitting member 1431 and the detection light receiving member 1432. Accordingly, at least the detection area 1422 of the reaction container 1420 is made of a light-transmitting material, so as to use the intensity of the detection light emitted by the detection light emitting member 1431 and the intensity of the scattered light or transmitted light received by the detection light receiving member 1432 to achieve the purpose of automatically detecting the turbidity of the sample to be detected by the turbidimetry method. In this embodiment, the light source of the turbidity detector 1430 can use laser or infrared light. In other embodiments, the turbidity detector 1430 can also use a sound wave turbidity detection device and the like.

[0049] The reagent adding pipe 1440 is mainly used for connecting with the matched reagent supply device to automatically inject the reagent (such as the staining agent, the diluent, the cleaning liquid, etc.) required due to the sample reaction or the corresponding operation into the holding space of the reaction container 1420. The reagent adding pipe 1440 is installed on the support frame 1410 and extends into the holding space. In this embodiment, the reagent adding pipe 1440 includes a diluent adding pipe, a staining agent adding pipe and a cleaning liquid adding pipe. The diluent adding pipe is mainly used for injecting the diluent into the reaction container 1420 when the turbidity of the sample to be detected detected by the turbidity detector 1430 is greater than the turbidity threshold value, so as to make the turbidity of the sample to be detected less than or equal to the turbidity threshold value, thereby meeting the requirements of the sample detection and analysis. The staining agent adding pipe is used for injecting the staining agent into the reaction container 1420 to stain the sample to be detected, thereby providing guarantee for the subsequent sample detection and analysis. The cleaning liquid adding pipe is mainly used for injecting the cleaning liquid into the reaction container 1420 to clean the residual sample and reagent in the reaction container 1420, thereby providing conditions for repeated use (or reaction processing of the next sample to be detected) of the sample reaction mechanism 1400, avoiding pollution between samples. In another embodiment, the reagent adding pipe 1440 can also use any one or more of the diluent adding pipe, the staining agent adding pipe and the cleaning liquid adding pipe according to the actual situation.

[0050] Therefore, the reaction container 1420, the turbidity detector 1430 and the reagent adding pipe 1440 are integrated as a whole by the support frame 1410. On the one hand, after the sample to be detected is added to the reaction container 1420, the turbidity detection operation item and the reagent adding operation item can be automatically performed, which can solve the problems of complicated operation steps and low efficiency due to the dependence on manual operation, enhance the automation degree of the sample reaction processing, guarantee the effect of the sample reaction processing, and create conditions for the subsequent sample conveying and sample detection. On the other hand, the whole sample reaction mechanism 1400 exists as a whole, which can effectively reduce the volume, the occupied space and the structural complexity of the sample conveying device in cooperation with the sample adding mechanism 300 and the conveying mechanism.

[0051] Please refer to Figures 1 to 4 , Figure 6 , Figure 15 and Figure 16In one embodiment, a gynecological secretion detection device is provided, comprising a conveying mechanism, a sample feeding mechanism 300, a sample reaction mechanism 1400, a detection mechanism, a driving mechanism 1200 and a controller 1300; wherein the conveying mechanism, the sample feeding mechanism 300 and the sample reaction mechanism 1400 are the conveying mechanism, the sample reaction mechanism 1400 and the sample feeding mechanism 300 adopted by the sample conveying device provided in the foregoing embodiments. In this embodiment, the conveying mechanism is a rotary conveying mechanism 100; in another embodiment, the conveying mechanism is a linear conveying mechanism.

[0052] The rotary conveying mechanism 100 operates in a rotary manner and is used to carry a detection card A (the detection card A is used to carry a sample to be detected); the sample feeding mechanism 300 and the detection mechanism are respectively arranged on the outer circumferential side of the rotary conveying mechanism 100 along the circumferential direction of the rotary conveying mechanism 100; the power output end of the driving mechanism 1200 is coupled to the rotary conveying mechanism 100 to drive the rotary conveying mechanism 100 to rotate around its axis (in this embodiment, the rotary conveying mechanism 100 rotates around the third direction); the controller 1300 is electrically connected with the sample feeding mechanism 300, the detection mechanism and the driving mechanism 1200, and the controller 1300 is used to: on the one hand, drive the rotary conveying mechanism 100 to rotate by controlling the driving mechanism 1200, and make the rotary conveying mechanism 100 stop due to the sample adding operation and the sample detection operation; on the other hand, control the sample feeding mechanism 300 to add the sample to be detected to the detection card A, and control the detection mechanism to detect the sample to be detected on the detection card A.

[0053] Please refer to Figure 3 and Figure 4 The rotary conveying mechanism 100 is provided with a plurality of sample card positions (such as 24 or other numbers set according to actual needs) distributed along the circumferential direction, and each sample card position can carry a detection card A (of course, after the sample to be detected is added to the detection card A, the sample card position is used to carry the sample to be detected); a plurality of functional positions are defined along the rotation track of the rotary conveying mechanism 100, including a sample adding position b and a detection position; the sample adding position b corresponds to the sample feeding mechanism 300, and the detection position corresponds to the detection mechanism; so that the sample adding position b, the reaction position n and the sample adding position b are arranged in the first direction in sequence, and the sample adding position b and the detection position are arranged in sequence along the conveying direction of the rotary conveying mechanism 100. The functional positions described in this application can be realized based on the software algorithm implanted in the controller 1300, the system function architecture or the combination of the two.

[0054] The detection method flow of the gynecological secretion detection device will be described below with some specific embodiments. Please refer to Figure 19, including the following steps: step 101, control the rotating of the carousel conveying mechanism 100, rotate the unused detection card A placed on the sample card position to the sample adding position b, stop and wait for the sample adding operation. Step 102, control the sample adding mechanism 300 to add the sample to be detected to the detection card A located at the sample adding position b during the stop of the carousel conveying mechanism 100; step 103, after the sample adding operation is completed, control the rotating of the carousel conveying mechanism 100, rotate the detection card A added with the sample to be detected to the detection position, stop and wait for the detection operation, and rotate the next unused detection card A to the sample adding position b; step 104, control the detection mechanism to detect the gynecological items of the sample to be detected on the detection card A located at the detection position during the stop of the carousel conveying mechanism 100.

[0055] In step 102, the sample adding mechanism 300 needs to perform the following sub-steps before adding the sample to be detected to the detection card A, please refer to Figure 20 , including the following steps: step 1021, control the sample adding mechanism 300 to suck the sample to be detected from the sampling position g, transport the sample to be detected to the reaction position n, and wait for the sample reaction operation. Step 1022, control the sample reaction mechanism 1400 to detect the turbidity of the sample to be detected, if the turbidity detection value is less than or equal to the turbidity threshold value, control the sample reaction mechanism 1400 to dye the sample to be detected; if the turbidity detection value is greater than the turbidity threshold value, control the sample reaction mechanism 1400 to dilute the sample to be detected until the turbidity detection value is less than or equal to the turbidity threshold value, and then control the sample reaction mechanism 1400 to dye the sample to be detected. Step 1023, control the sample adding mechanism 300 to suck the dyed sample to be detected from the sample reaction mechanism 1400, and transport the sample to be detected to the sample adding position b. Step 1024, after the sample to be detected is added to the detection card A, clean the sample adding mechanism 300 (for example, if the cleaning mechanism exists, control the sample adding mechanism 300 to move to the cleaning position p, so that the cleaning mechanism cleans the sample adding mechanism 300), thereby completing the complete transport process of one sample.

[0056] In summary, for the detection of the same sample, the controller 1300 controls the driving mechanism 1200 to drive the rotating disc conveying mechanism 100 to rotate, so that the detection card A (or sample card position) carrying the sample can rotate to the sample adding position b and the detection position in turn. When the rotating disc conveying mechanism 100 stops due to the addition of the sample and the sample detection operation, the controller 1300 controls the sample adding mechanism 300 to perform the sample adding operation and controls the detection mechanism to complete the sample detection operation, so as to realize the one-by-one operation of multiple task items of the same sample to be detected and the continuous completion of the detection of multiple samples to be detected. At the same time, after the sample adding mechanism 300 adds the sample to be detected to the detection card A, the sample adding mechanism 300 and the sample reaction mechanism 1400 are used to perform the sampling and sample reaction processing operations in the first direction during the rotation of the rotating disc conveying mechanism 100 or the waiting for the corresponding operation. First, in terms of the structure layout of the detection device, the sample adding mechanism 300 is used to form a sample conveying device arranged in the first direction on the side of the rotating disc conveying mechanism 100. At the same time, the sample adding mechanism 300 and the detection mechanism are arranged around the rotating disc conveying mechanism 100, and a detection device with the rotating disc conveying mechanism 100 as the center is formed, which can effectively reduce the volume and occupied space of the entire device. Compared with the existing straight-line assembly line type detection device, the structure of the detection device can be more compact, which can create conditions for the miniaturization and compact structure design of the device. Second, in terms of the efficiency of sample detection, the sample conveying operation is independent of the sample detection operation, which can create favorable conditions for improving the detection efficiency of the detection device.

[0057] In this embodiment, the driving mechanism 1200 can be composed of existing power output devices such as motors and related devices such as reducers and encoders. The controller 1300 can be a computer, a single-chip microcomputer, a PLC controller 1300, or a distributed or centralized control system, which can be used to coordinate and control the various mechanisms in the detection device, including but not limited to the start-stop control of the various mechanisms, the transmission of sample images, the reception and feedback of signals, etc. The controller 1300 has the function of indirectly controlling or directly controlling the above-mentioned mechanisms to perform corresponding operation actions, which can be realized based on software algorithms implanted in the controller 1300, system function architecture, or a combination of the two. Therefore, the driving mechanism 1200 and the controller 1300 are not described here.

[0058] In one embodiment, please refer to Figure 1 、 Figure 2 、 Figure 3 and Figure 4The rotating disc type conveying mechanism 100 comprises a base disc 101 and a plurality of clamping protrusions 102 arranged on the axial surface (also understood as the axial end surface or disc surface) of the base disc 101 in the circumferential direction, each clamping protrusion 102 is distributed along the radial direction of the base disc 101, so that the clamping protrusions 102 on the axial surface of the base disc 101 present a radial structure form with the axis of the base disc 101 as the base point, and the clamping position is naturally formed between two adjacent clamping protrusions 102, the spatial shape of the clamping position is consistent with the shape of the detection card, and at the same time, due to the certain interval space between the two adjacent clamping protrusions 102, the clamping position exists in the radial direction of the base disc 101 in a way that the inner and outer peripheries are penetrated; thus, the clamping position formed by the two adjacent clamping protrusions 102 can provide a convenient structural channel for the execution of actions such as adding a detection card A (i.e., an upper card) or removing a detection card A.

[0059] In one detection cycle, the carousel conveying mechanism 100 rotates and stops waiting according to the operation sequence steps of adding samples and sample detection, and in this process, the gynecological item detection is performed according to the following steps: step 11, the controller 1300 issues a task of judging whether the detection card A exists in the adding sample position b and the detection position c; if it exists, steps 13 and 15 are executed at the same time; if it does not exist, the detection card A is added to the card position located at the predetermined initial position, and step 12 is executed. Step 12, the carousel conveying mechanism 100 rotates one card position (i.e., equivalent to advancing one card position) at a predetermined time interval, and at the same time, a detection card A is added to the corresponding card position from the predetermined initial position at each predetermined time interval (i.e., stop waiting) of the carousel conveying mechanism 100; if the detection card A exists in the adding sample position b, step 13 is executed; if it does not exist, it is queried and waits. Step 13, the carousel conveying mechanism 100 stops waiting, and the sample adding mechanism 300 performs the sample adding operation to add the sample to be detected to the detection card A; if the execution is successful, step 14 is executed; if the execution fails, the fault information is reported to the controller 1300, and after the fault is eliminated, the sample adding operation is continued. Step 14, the carousel conveying mechanism 100 continues to rotate one card position at a predetermined time interval, and if the detection card exists in the detection position, step 15 is executed; if it does not exist, it is queried and waits. Step 15, the carousel conveying mechanism 100 stops waiting, and the detection mechanism performs the sample detection operation, first moves the detection card A to which the sample to be detected is added from the card position located at the detection position, and then detects the sample to be detected on the detection card A, and after the detection is completed, the detection card A is moved into the card position located at the detection position or the detection card A after the detection is completed is directly discarded; if the execution is successful, step 16 is executed; if the execution fails, the fault information is reported to the controller 1300, and after the fault is eliminated, the sample detection operation is continued. Step 16, the carousel conveying mechanism 100 continues to rotate one card position at a predetermined time interval, and at the same time, the detection card A after the detection is completed is removed from the carousel conveying mechanism 100 before it reaches the predetermined initial position, so as to continuously add the unused detection card A to the carousel conveying mechanism 100; in this way, a plurality of samples to be detected are continuously detected.

[0060] In one embodiment, please refer to Figure 1 、 Figure 2 、 Figure 3 and Figure 4 , the end of the protrusion 102 is provided with a pressing arm 103 extending into the card position, which is used to press the surface of the detection card A, so that the detection card A is stably positioned on the card position, and during the rotation of the base disc 101, the detection card A can be prevented from being separated from the card position due to the centrifugal force. The pressing arm 103 can have a certain elastic ability, which can ensure that a certain pressing force is generated on the detection card A, and the detection card A is not completely stuck in the card position.

[0061] In one embodiment, the detection card A has a dry chemical area and a microscopic area; when the sample adding mechanism 300 performs the operation of adding the sample to be detected to the detection position b, the general principle should include the following steps: 1. The sample adding mechanism 300 sucks the sample to be detected. 2. Add the first part of the sample to be detected to the dry chemical area of the detection card A. 3. Add the second part of the sample to be detected to the sample reaction mechanism 1400. 4. The staining mechanism performs turbidity detection, dilution, staining and other processes on the sample to be detected. 5. The sample adding mechanism 300 adds the stained sample to be detected to the microscopic area of the detection card A at the sample adding position b.

[0062] In this embodiment, referring to Figure 1 and Figure 2 , the detection mechanism includes a microscopic mechanism 400 and a photographing mechanism 600; accordingly, the detection position includes a microscopic position c and a photographing position e, the microscopic mechanism 400 corresponds to the microscopic position c, and the photographing mechanism 600 corresponds to the photographing position e; the sample adding mechanism 300, the microscopic mechanism 400 and the photographing mechanism 600 are sequentially arranged on the outer circumferential side of the turntable conveying mechanism 100 along the circumferential direction of the turntable conveying mechanism 100. And the gynecological project includes microscopic detection projects and dry chemical detection projects, accordingly, the detection card A carried and transported by the turntable conveying mechanism 100 has a dry chemical area and a microscopic area; the microscopic mechanism 400 is used for detecting at least one of the microscopic detection projects to obtain information of formed elements in the sample; the photographing mechanism 600 is used for detecting at least one of the dry chemical detection projects to obtain reaction structure information of the sample.

[0063] Referring to Figure 21 , step 104 specifically includes: step 1041, controlling the turntable conveying mechanism 100 to first rotate the detection card A to which the sample to be detected is added to the microscopic position c, and stop waiting for the microscopic scanning operation. Step 1042, control the microscopic mechanism 400 to move the detection card A at the microscopic position c from the turntable conveying mechanism 100, and perform microscopic scanning on the sample to be detected in the microscopic area of the detection card to complete at least one of the microscopic detection projects. Step 1043, after the microscopic scanning is completed, control the microscopic mechanism 400 to move the detection card A into the turntable conveying mechanism 100. Step 1044, control the turntable conveying mechanism 100 to rotate, and rotate the detection card A on which the microscopic scanning is completed to the photographing position e, and stop waiting for the photographing operation. Step 1045, control the photographing mechanism 600 to move the detection card A at the photographing position e from the turntable conveying mechanism 100, and perform photographing on the sample to be detected in the dry chemical area of the detection card A to complete at least one of the dry chemical detection projects; at the same time, the detection card A is discarded and recycled.

[0064] In another embodiment, the detection mechanism can be one of the mirror detection mechanism 400 and the photographing mechanism 600, and correspondingly, the detection position is the mirror detection position c or the photographing position d. In this embodiment, the detection card A can only have the mirror detection area or the dry chemical area. If the detection mechanism is the mirror detection mechanism 400, after the mirror detection scanning of the sample to be detected is completed, the detection card A is directly discarded and recycled. If the detection mechanism is the photographing mechanism 600, after the photographing imaging of the sample to be detected is completed, the detection card A is directly discarded and recycled. In this way, the detection card A that has completed the detection is removed from the rotating disc conveying mechanism 100, which creates conditions for the subsequent addition of the detection card and the cyclic detection of more samples to be detected.

[0065] Referring to Figure 1 In an embodiment, the gynecological secretion detection device further comprises a color developing mechanism 500 for adding a color developing agent to the sample to be detected before the photographing operation, so as to create a prerequisite for the photographing imaging operation. Correspondingly, the function position further comprises a color developing position d. The color developing mechanism 500 adopts an existing product, mainly a color developing agent supply system composed of a liquid pump, a pipeline, a valve and the like, and the specific structure is not described herein. If the detection mechanism is the photographing mechanism 600, the sample feeding mechanism 300, the color developing mechanism 500 and the photographing mechanism 600 are sequentially arranged on the outer circumferential side of the rotating disc conveying mechanism 100 along the circumferential direction of the rotating disc conveying mechanism 100. If the detection mechanism comprises the mirror detection mechanism 400 and the photographing mechanism 600, the sample feeding mechanism 300, the mirror detection mechanism 400, the color developing mechanism 500 and the photographing mechanism 600 are sequentially arranged on the outer circumferential side of the rotating disc conveying mechanism 100 along the circumferential direction of the rotating disc conveying mechanism 100. In this embodiment, referring to Figure 21 Step 104 further comprises: step 1046, after the detection by the mirror detection mechanism 400 and before the detection by the photographing mechanism 600, the rotating disc conveying mechanism 100 is controlled to rotate, so as to rotate the detection card A that has completed the mirror detection scanning to the color developing position d and stop to wait for the color developing operation. Step 1047, the color developing mechanism 500 is controlled to add the color developing agent to the dry chemical area of the detection card A located at the color developing position d, so as to rotate the detection card A to which the color developing agent is added to the photographing position e.

[0066] In this embodiment, the color developing mechanism 500 can complete the operation of adding the color developing agent according to the following action flow steps, specifically: step 51, judging whether the color developing position d exists the detection card A; if yes, executing step 52; if no, querying the waiting. Step 52, judging whether the state of the color developing mechanism 500 is the state of waiting for adding the color developing agent; if yes, executing step 53; if no, querying the waiting. Step 53, judging whether the incubation of the detection sample to be detected is completed; if yes, executing step 54; if no, querying the waiting. Step 54, executing the action of adding the color developing agent, judging whether the color developing agent is successfully added; if yes, executing step 55; if no, reporting the fault information to the controller 1300, and continuing to execute after the fault is eliminated. Step 55, judging whether the adding of the color developing agent is completed; if yes, executing step 56; if no, querying the waiting. Step 56, updating the state of adding the color developing agent, and executing step 51.

[0067] In one embodiment, please refer to 1, Figure 2 , Figure 7 and Figure 8 The microscope mechanism 400 mainly includes a carrier assembly 410, and a first push card assembly 420 and a microscope assembly 430 (which mainly consists of a focusing lens and a microscope light source) installed on the carrier assembly 410, and at least the first push card assembly 420 and the microscope assembly 430 are respectively electrically connected with the controller 1300; wherein the carrier assembly 410 is arranged at the outer circumferential side of the rotary disc type conveying mechanism 100, for carrying the detection card A pushed out from the card position and carrying the detection sample to be detected, the first push card assembly 420 is installed on the carrier assembly 410 and electrically connected with the controller 1300, and the first push card assembly 420 reciprocally walks between the rotary disc type conveying mechanism 100 and the carrier assembly 410 along the radial direction of the rotary disc type conveying mechanism 100, so as to push the detection card A rotating to the microscope position c and carrying the detection sample to be detected from the card position to the carrier assembly 410 when the rotary disc type conveying mechanism 100 stops due to the microscope scanning operation, so that the detection card A is aligned with the microscope assembly 430, and then the microscope assembly 430 is used to perform the microscope scanning on the detection sample to be detected; after the microscope scanning of the detection sample to be detected is completed, the detection card A is pushed from the carrier assembly 410 to the card position located at the microscope position c, or the detection card A is removed from the carrier assembly 410, so as to perform the card discarding and recycling treatment on the detection card A.

[0068] In one embodiment, please refer to Figure 8The first push-pull assembly 420 comprises a first push-pull driving member 421 and a first push-pull linkage. The first push-pull driving member 421 can be a power element such as a motor or a pneumatic cylinder. The body of the first push-pull driving member 421 is mounted on the object carrying assembly 410. The power output end of the first push-pull driving member 421 is connected to the first push-pull linkage through a transmission mode such as synchronous belt transmission, screw transmission or direct connection. The first push-pull linkage has a first push-pull arm 422 and a second push-pull arm 423. The first push-pull arm 422 is vertically distributed parallel to the axial direction of the rotary disc conveying mechanism 100. The second push-pull arm 423 is horizontally distributed parallel to the radial direction of the rotary disc conveying mechanism 100. The body of the first push-pull linkage is linearly and slidingly connected to the object carrying assembly 410 (e.g. guide rail + sliding groove). When the microscopic examination mechanism 400 does not perform the microscopic examination scanning operation, the detection card A on the clamping position at the microscopic examination position c is located between the first push-pull arm 422 and the second push-pull arm 423. When the first push-pull driving member 421 drives the first push-pull linkage to move away from the rotary disc conveying mechanism 100 along the radial direction of the rotary disc conveying mechanism 100, the first push-pull arm 422 abuts against the side wall of the end of the rotary disc conveying mechanism 100 towards the shaft, thereby pushing the detection card A onto the object carrying assembly 410. Conversely, after the microscopic examination scanning of the detection card A is completed by the microscopic assembly 430, when the first push-pull driving member 421 drives the first push-pull linkage to move towards the shaft of the rotary disc conveying mechanism 100 along the radial direction of the rotary disc conveying mechanism 100, the second push-pull arm 423 abuts against the side wall of the end of the object carrying assembly 410, thereby pushing the detection card A into the clamping position at the microscopic examination position c. Of course, in another embodiment, only the first push-pull arm 422 can be provided. After the microscopic examination scanning is completed, the first push-pull linkage continues to move away from the rotary disc conveying mechanism 100, so as to move the detection card A out of the object carrying assembly 410 by using the first push-pull arm 422, and finally achieve the detection card A recycling processing.

[0069] In one embodiment, please refer to Figure 8The carrier assembly 410 comprises a support platform 411, a scanning platform 412 and a scanning driving element 413; wherein the support platform 411 is fixedly assembled near the rotating track of the rotating disc type conveying mechanism 100 and is used as a support carrier of the microscope assembly 430 and the first push-clamp assembly 420; the scanning platform 412 is linearly slidably connected with the support platform 411 (such as guide rail + sliding groove), and the sample conveying groove 414 and the perspective window 415 are arranged on the surface of the scanning platform 412; the scanning driving element 413 can be a power element such as a motor or a pneumatic cylinder and is connected with the controller 1300, the body of the scanning driving element 413 is installed on the scanning platform 412, and the power output end of the scanning driving element 413 can be connected with the scanning platform 412 in a mode such as synchronous belt transmission, screw rod transmission or direct connection based on the specific type of the scanning driving element 413; when the first push-clamp assembly 420 pushes the detection card A out from the card position at the microscope position c, the detection card A enters the perspective window 415 through the sample conveying groove 414; at this time, based on the requirement that the to-be-detected sample needs to be aligned with the microscope assembly 430, the controller 1300 can control the scanning driving element 413 to drive the scanning platform 412 to move on the support platform 411 along the radial direction of the rotating disc type conveying mechanism 100, so that the microscope assembly 430 is aligned with the detection card A in the perspective window 415, and then the fine adjustment or precise adjustment of the final position of the detection card A in the microscope scanning mechanism 400 is realized, and the smooth completion of the microscope scanning operation is ensured.

[0070] The microscope mechanism 400 in the embodiment of the application can complete the microscope scanning operation according to the following action flow steps, specifically: step 41, judging whether the detection card A added with the sample to be detected exists on the card position at the microscope position c; if yes, executing step 42; if no, querying waiting. Step 42, judging whether the state of the microscope mechanism 400 is the state of waiting for microscope; if yes, executing step 43; if no, querying waiting. Step 43, executing the microscope lamp source opening action of the microscope assembly 430, executing the action of pushing the detection card A into the object carrier assembly 410 by the first push card assembly 420, and aligning the sample to be detected on the detection card A with the focusing lens of the microscope assembly 430; if the execution is successful, executing step 44; if the execution fails, reporting the fault information to the controller 1300, and continuing to execute after the fault is eliminated. Step 44, executing the focusing microscope action of the focusing lens of the microscope assembly 430, and judging whether the microscope scanning is successful; if yes, executing step 45; if no, reporting the fault information to the controller 1300, and continuing to execute after the fault is eliminated. Step 45, judging whether the microscope scanning is completed; if yes, executing step 46; if no, querying waiting. Step 46, executing the microscope lamp source closing action of the microscope assembly 430, executing the action of pushing the detection card A into the card position of the rotary disc type conveying mechanism 100 by the first push card assembly 420 or executing the action of forcibly moving the detection card A away from the object carrier assembly 410 by the first push card assembly 420, so that the detection card A reenters the rotary disc type conveying mechanism 100 or is discarded and recycled; if the execution is successful, executing step 47; if the execution fails, reporting the fault information to the controller 1300, and continuing to execute after the fault is eliminated. Step 47, updating the microscope state, and executing step 41.

[0071] In one embodiment, referring to Figure 1 、 Figure 2 and Figure 9The photographing mechanism 600 comprises a second material carrying platform 601, a photographing function part 602, a second push-and-pull driving part 603, a base plate 604, a second push-and-pull linkage part 605 and a waste card collecting bin 606. The second material carrying platform 601 is arranged at the outer circumferential side of the rotating disc type conveying mechanism 100, and is used to carry the detection card A (the detection card A carries the sample to be detected with the color developing agent added) moved out from the card position rotated to the photographing position e. The photographing function part 602 is mainly composed of existing products such as CCD camera and dry chemical light source, and is installed on the second material carrying platform 601 and electrically connected with the controller 1300. The image pickup surface of the photographing function part 602 faces the surface of the second material carrying platform 601, and is used to take photograph of the reaction structure of the sample to be detected (i.e. the sample to be detected carried on the detection card A) transferred to the second material carrying platform 601. The base plate 604 is installed on the second material carrying platform 601, and is mainly used to provide structural assembly space for the second push-and-pull driving part 603 and the second push-and-pull linkage part 605. The second push-and-pull driving part 603 can be a power element such as motor or air cylinder according to actual situation. The second push-and-pull driving part 603 is electrically connected with the controller 1300, and the body of the second push-and-pull driving part 603 is installed on the base plate 604. The waste card collecting bin 606 is located at the side of the second material carrying platform 601 away from the rotating disc type conveying mechanism 100 (also can be understood as located at the end of the walking stroke of the second push-and-pull linkage part 605). The second push-and-pull linkage part 605 is connected with the power output end of the second push-and-pull driving part 603, and is linearly slidably connected with the base plate 604 (such as through the cooperation structure of guide rail and sliding groove). The second push-and-pull driving part 603 drives the push-and-pull linkage part 605 to walk along the radial direction of the rotating disc type conveying mechanism 100 between the rotating disc type conveying mechanism 100 and the waste card collecting bin 606, so as to push the detection card A rotated to the photographing position e from the card position to the second material carrying platform 601 and align with the photographing function part 602, thereby making the photographing function part 602 take photograph of the sample to be detected. After the photographing is completed, the controller 1300 controls the second push-and-pull driving part 603 to continue driving the push-and-pull linkage arm 605 to walk, thereby pushing the detection card A into the waste card collecting bin 606, and completing the card discarding and collecting operation of the detection card A.

[0072] In one embodiment, referring to Figure 9The second push-and-pull linkage 605 has a third push-and-pull arm 607 extending towards the upper surface side of the second object platform 601 along the axial direction of the rotary disc conveying mechanism 100. The third push-and-pull arm 607 can abut against the side wall of the rotary disc conveying mechanism 100 at the end of the shaft center from the inner circumferential side of the card slot, so that the detection card A is pushed out of the card slot by the third push-and-pull arm 607 during the driving of the second push-and-pull linkage 605 by the second push-and-pull driving member 603. In this embodiment, the second push-and-pull driving member 603 is a motor, and the power output end of the second push-and-pull driving member 603 is connected with the second push-and-pull linkage 605 through a synchronous belt 608. Of course, the connection between the power output end of the second push-and-pull driving member 603 and the second push-and-pull linkage 605 can also be a screw transmission structure, a gear and rack transmission structure, etc. In other embodiments, the second push-and-pull driving member 603 can also be a pneumatic cylinder, and the second push-and-pull linkage 605 is directly connected with the output shaft of the pneumatic cylinder.

[0073] The photographing mechanism 600 in the embodiment of the present application can complete the sample photographing operation according to the following action flow steps. Specifically, step 61: judging whether the detection card A added with the sample to be detected exists in the card slot at the photographing position e; if yes, executing step 62; if not, querying and waiting. Step 62: judging whether the state of the photographing mechanism 600 is the state of being ready for photographing; if yes, executing step 63; if not, querying and waiting. Step 63: executing the starting action of the dry chemical light source of the photographing function member 602, executing the action of pushing the detection card A into the second object platform 601 by the second push-and-pull linkage 605, and aligning the sample to be detected on the detection card A with the photographing function member 602; if the execution is successful, executing step 64; if the execution fails, reporting the fault information to the controller 1300, and continuing the execution after the fault is eliminated. Step 64: executing the photographing action of the photographing function member 602, and judging whether the photographing is successful; if yes, executing step 65; if not, reporting the fault information to the controller 1300, and continuing the execution after the fault is eliminated. Step 65: judging whether the photographing imaging is completed; if yes, executing step 66; if not, querying and waiting. Step 66: executing the closing action of the dry chemical light source of the photographing function member 602, executing the action of pushing the detection card A into the waste card collection bin 606 by the second push-and-pull linkage 605, and realizing the card discarding and recycling of the detection card A; if the execution is successful, executing step 66; if the execution fails, reporting the fault information to the controller 1300, and continuing the execution after the fault is eliminated. Step 67: updating the photographing state, and executing step 61.

[0074] Please refer to Figure 3In the embodiment, the gynecological secretion detection device further comprises an incubation mechanism 1000 electrically connected with the controller 1300, and used for heating the sample to be detected on the rotating disc conveying mechanism 100, so that the temperature of the sample to be detected is kept in a preset range. The incubation mechanism 1000 can be in structural and functional cooperation with the rotating disc conveying mechanism 100 in a contact heat conduction mode or a radiation heat conduction mode. In an embodiment, the incubation mechanism 1000 is arranged opposite to the rotating disc conveying mechanism 100 (i.e., located below the rotating disc conveying mechanism 100).

[0075] In the presence of the photographing mechanism 600, the incubation mechanism 1000 is controlled to heat the sample to be detected on the rotating disc conveying mechanism 100, so that the sample to be detected can be heated after being added on the detection card A, thereby performing the incubation heating reaction, which creates favorable conditions for shortening the waiting time of the photographing operation of the photographing mechanism 600, and further effectively improves the operation and detection efficiency of the detection device. In the presence of the microscope mechanism 400, the sample to be detected can be quickly removed from the rotating disc conveying mechanism 100 after being rotated to the microscope position c, which not only completes the detection of the sample in the microscope project, but also avoids the incubation mechanism 1000 from drying the sample to be detected, thereby ensuring the quality of the microscope scanning.

[0076] In an embodiment, the incubation mechanism 1000 comprises a base, a substrate 1001 and a heating film. The substrate 1001 is arranged below the rotating disc conveying mechanism 100 and is distributed opposite to the rotating disc conveying mechanism 100. The heating film is attached to the surface of the substrate 1001 close to the rotating disc conveying mechanism 100. The heating film is electrically connected with the controller 1300 to receive the control of the controller 1300. The substrate 1001 is connected with the base, so that the substrate 1001 and the heating film remain in a stationary state (i.e., do not move with the rotation of the rotating disc conveying mechanism 100) when the rotating disc conveying mechanism 100 rotates, thereby facilitating the wiring arrangement of the heating film, i.e., optimizing the structure of the device and preventing the occurrence of problems such as winding.

[0077] In an embodiment, please refer to Figure 1 、 Figure 2 and Figure 3The incubation mechanism 1000 further comprises a heat preservation cover 1002 installed on the rotary disc conveying mechanism 100, which is used to cover the area between the mirror inspection position c and the photographing position e in the presence of the mirror inspection mechanism 400, or the area between the sample adding position b and the photographing position e in the absence of the mirror inspection mechanism 400, so as to ensure the incubation effect of the sample to be detected in the covered area by the heat preservation cover 1002, thereby improving the detection efficiency of the detection device by shortening the incubation time as much as possible.

[0078] In one embodiment, based on the incubation mechanism 1000 and the implementation condition that the sample adding mechanism 300, the mirror inspection mechanism 400 and the photographing mechanism 600 are arranged at least on the outer periphery of the rotary disc conveying mechanism 100, the rotation period of the rotary disc conveying mechanism 100 can be determined based on the structural characteristics of the above mechanisms distributed around the rotary disc conveying mechanism 100 and the time sequence requirement of the detection process steps, so as to realize the scheduling of the entire detection process. Please refer to Figure 22 The detection scheduling method comprises the following steps: step 201, controlling the incubation mechanism 1000 to heat the sample to be detected on the rotary disc conveying mechanism 100. Step 202, control the rotary disc conveying mechanism 100 to rotate and transfer the sample to be detected from the sample adding position b to the detection position. In one detection cycle, the rotation period of the rotary disc conveying mechanism 100 is determined based on the preset heating time of the sample to be detected on the rotary disc conveying mechanism 100.

[0079] In one embodiment, step 202 is specifically: controlling the rotary disc conveying mechanism 100 to rotate step by step according to the number of clamping positions, so as to transfer the sample to be detected from the sample adding position c to the detection position. In one detection cycle, the progressive period (or step period) of the rotary disc conveying mechanism 100 is determined based on the preset heating time of the sample to be detected on the rotary disc conveying mechanism 100. More specifically, since there are a plurality of clamping positions (represented by the number S) between the sample adding position b and the photographing position e, controlling the rotary disc conveying mechanism 100 to rotate step by step according to the number of clamping positions is specifically:

[0080] The carousel conveying mechanism 100 is controlled to rotate one card position every Δt time, and the Δt time is determined based on the following formula: Δt = T / S, wherein T is the preset heating time of the sample to be detected on the carousel conveying mechanism, and S is an integer greater than 1. In order to ensure that the multiple samples to be detected can be detected one by one in a cycle, based on the selection of the heating temperature of the incubation mechanism 1000, the Δt time is at least greater than the time required for the microscope mechanism 400 to complete the microscope scanning operation and the time required for the sample adding mechanism to complete the sample adding operation. In this way, the related operation tasks of each mechanism, the close connection between the tasks, and the cycle continuous detection of the sample can be created to create favorable conditions.

[0081] Please refer to Figure 1 、 Figure 2 、 Figure 4 、 Figure 10 、 Figure 11 and Figure 12 In one embodiment, a gynecological secretion detection device is provided, further comprising a sample feeding mechanism 700 and an elution mechanism 800. The sample feeding mechanism 700 is arranged on the outer periphery of the carousel conveying mechanism 100 and is controllably movable in the second direction, and is used to convey the sample test tube B (which is used to contain the sample to be detected). The elution mechanism 800 is arranged on the side of the sample feeding mechanism 700 (for example, between the carousel conveying mechanism 100 and the sample feeding mechanism 800), and the main function is: when the sample feeding mechanism 700 stops due to dilution and elution operation, the elution mechanism 800 is controlled to first add eluent (i.e. diluent) into the sample test tube B on the test tube station moved to the elution position f, and then stir and mix the sample to be detected and the eluent in the sample test tube B, thereby realizing the elution of the sample. The sample test tube B is used for dilution and elution treatment of the sample to be detected. Wherein, the controller 1300 is electrically connected with the sample feeding mechanism 700 and the elution mechanism 800 respectively, so that the controller 1300 has the function of indirectly controlling or directly controlling the sample feeding mechanism 700, the elution mechanism 800 and the sample feeding mechanism 300 to perform dilution and elution and sample suction operation respectively. This function can be realized based on the software algorithm, system function architecture or the combination of the two implanted in the controller 1300.

[0082] Please refer to the drawings Figure 10 and Figure 11The sample feeding mechanism 700 is provided with a plurality of test tube stations arranged in a straight line along the advancing direction of the second direction, each of which can carry a sample test tube B; the movement track of the sample feeding mechanism 700 defines an elution position f and a sampling position g; the elution mechanism 800 is fixedly aligned or movably aligned with the elution position f, and the sample feeding mechanism 300 is movably aligned with the sampling position g. In the specific implementation, if the axis of the rotating disc conveying mechanism 100 is located on the Z axis (i.e., the rotating disc conveying mechanism 100 rotates around the Z axis), and the sample feeding mechanism 300 is arranged near the rotating track of the rotating disc conveying mechanism 100 along the X axis direction, the sample feeding mechanism 700 can be arranged on the side of the rotating track of the rotating disc conveying mechanism 100 along the Y axis direction. Through this layout, conditions can be created for minimizing the structural volume of the device and improving the structural compactness of the device after the device is configured with the sample feeding mechanism 700, the elution mechanism 800 and other mechanisms.

[0083] In this embodiment, the sample feeding mechanism 700 can use a test tube rack device with an automatic test tube advancing function in the prior art to realize the function of conveying the sample test tube B along a straight line. Please refer to Figure 10 and Figure 11 , which can specifically include a test tube rack 701 and a linear transmission assembly 702. The test tube rack 701 is installed on the linear transmission assembly 702, and the test tube stations are arranged on the test tube rack 701 and distributed along a straight line parallel to the transmission direction of the linear transmission assembly 702. The linear transmission assembly 702 can be a linear transmission structure of a motor + synchronous belt, a linear transmission structure of a motor + screw, or a linear transmission structure of a cylinder directly connected to the test tube rack 701. Thus, the test tube rack 701 can be conveyed along a straight line by using the linear transmission assembly 702, so that the test tube stations on the test tube rack 701 are transferred to the elution position f and the sampling position g one by one. Since the sample feeding mechanism 700 can use the prior art, it will not be described in detail here.

[0084] From the perspective of sample feeding, for the same sample, the controller 1300 controls the sample feeding mechanism 700 to move, so that the test tube station carrying the sample can be moved to the elution position f and the sampling position g in sequence. When the sample feeding mechanism 700 stops due to the dilution elution and sample suction operations, the controller 1300 controls the elution mechanism 700 and the sample feeding mechanism 300 to perform the dilution elution and sample suction operations in a timely manner. When the rotating disc conveying mechanism 100 stops due to the sample addition operation, the controller 1300 controls the sample feeding mechanism 300 to suck the sample to be detected from the sample test tube B and finally add the sample to be detected to the detection card A located at the sample addition position b, so that the rotating disc conveying mechanism 100 continues to operate. For multiple samples, the dilution elution and sample suction operations of at least two different samples can be completed simultaneously during the conveying of the sample feeding mechanism 700.

[0085] Since the work of completing the gynecological secretion sample detection needs to perform pretreatment operations such as sample feeding and sample sending, dilution and elution, sample staining, cleaning and the like, and subsequent detection operations such as sample suction, sample adding, detection (such as microscopic scanning, photographing and imaging), the carousel conveying mechanism 100 is used to integrate operation tasks such as adding a detection card, adding a sample, microscopic scanning, adding a color developing agent, photographing and imaging, and discarding a card on the same control thread (which can be defined as a first task thread), and the sample feeding mechanism 700 is used to integrate operation tasks such as sample feeding and sample sending, dilution and elution, sample suction and sample staining on another control thread (which can be defined as a second task thread), so that the first task thread and the second task thread are separated from each other and can be executed synchronously. On the one hand, since the first task thread and the second task thread independently execute related operation tasks, the dependency between tasks can be reduced, the waiting time before execution of each operation task can be reduced, and thus the running and detection efficiency of the detection device can be improved. On the other hand, each mechanism involved in the first task thread forms a rotating carousel platform assembly around the carousel conveying mechanism 100, each mechanism involved in the second task thread forms a linear sample feeding platform assembly around the sample feeding mechanism 700, and the two assemblies are connected through the sample feeding mechanism 300. Not only can each mechanism be more compact in structure layout, further reducing the volume of the detection device, but also the independent running control of each mechanism or the two assemblies can effectively ensure the stability of the detection device running and reduce the failure rate, providing a guarantee for improving the running and detection efficiency of the device.

[0086] In one embodiment, referring to Figure 10 , Figure 11 and Figure 12 , the elution mechanism 800 includes a translation guide seat 801, a lifting guide seat 802, a translation travel driving member 803, a lifting travel driving member 804, an elution liquid sample adding assembly 805, a stirring rod 806, a stirring motor 807 and a stirring positioning seat 808. Among them:

[0087] The translation guide seat 801 is arranged near the walking movement track of the sample feeding mechanism 700, the bottom end of the lifting guide seat 802 is linearly and slidably connected with the translation guide seat 801 (for example, by a sliding rail and sliding groove matching structure), the eluent sample adding assembly 805 is installed at the bottom end of the lifting guide seat 802, the body of the translation travel driving part 803 is arranged at one end of the translation guide seat 801, the power output end of the translation travel driving part 803 is connected with the base of the lifting guide seat 802, and the translation travel driving part 803 is electrically connected with the controller 1300; the translation travel driving part 803 is used to drive the lifting guide seat 802 and the eluent sample adding assembly 805 to synchronously and linearly reciprocate on the translation guide seat 801 (the reciprocating direction is perpendicular to the walking movement direction of the sample feeding mechanism 700, for example, if the walking movement direction of the sample feeding mechanism 700 is the left-right direction, the moving direction of the lifting guide seat 802 and the eluent sample adding assembly 805 is the front-back direction), so that when the eluent sample adding assembly 805 moves to the elution position f, the eluent is added into the sample test tube B located at the elution position f.

[0088] The stirring positioning seat 808 is linearly and slidably connected with the lifting guide seat 802 (for example, by a sliding rail and sliding groove matching structure), the body of the stirring motor 807 is installed on the stirring positioning seat 808, the power output end of the stirring motor 807 is connected with the stirring rod 806, the body of the lifting travel driving part 804 is installed on the top end side of the lifting guide seat 802, the power output end of the lifting travel driving part 804 is connected with the stirring positioning seat 808, and the lifting travel driving part 804 and the stirring motor 807 are electrically connected with the controller 1300 respectively; the lifting travel driving part 804 is used to drive the stirring positioning seat 808, the stirring motor 807 and the stirring rod 806 to synchronously and vertically lift on the lifting guide seat 802, so that the stirring rod 806 can enter the sample test tube B in the test tube station at the elution position f, and then the stirring motor 807 is used to drive the stirring rod 806 to fully stir and mix the sample to be detected and the eluent in the sample test tube B, so as to realize the elution of the sample.

[0089] In this embodiment, the translation travel driving part 803 and the lifting travel driving part 804 can adopt power devices such as motors and air cylinders according to actual conditions, and the connection modes between the translation travel driving part 803 and the lifting guide seat 802 and between the lifting travel driving part 804 and the stirring positioning seat 808 include but are not limited to modes such as screw transmission connection, synchronous belt transmission connection, gear and rack transmission connection and the like.

[0090] In one embodiment, please refer to Figure 12The power output shaft of the stirring motor 807 is connected to the stirring rod 806 in an eccentric manner, so that the stirring motor 807 drives the stirring rod 806 to rotate eccentrically, so as to realize eccentric stirring of the sample to be detected in the sample test tube B. This can effectively eliminate the vortex in the liquid medium (i.e., the sample and the diluent) in the sample test tube B, strengthen the turbulent flow between the liquid layers, shorten the reaction time of the sample and the diluent, improve the stirring efficiency, and avoid problems such as falling of the sample test tube B from the sample adding mechanism 700 and leakage of the sample liquid from the sample test tube B by reducing the high-speed oscillation risk in the stirring process.

[0091] In one embodiment, referring to Figure 10 、 Figure 11 、 Figure 13 and Figure 14 , the elution mechanism 800 further comprises a pressing assembly for elastically pressing the test tube rack 701 in the sample adding mechanism 700 and the sample test tube B being diluted and eluted, so as to reduce the vibration amplitude of the sample test tube B when being subjected to eccentric stirring, avoid affecting the sample test tubes B on other test tube stations, and ensure the normal execution of processes such as sample suction and subsequent code scanning. The pressing assembly comprises a pressing guide seat 809, a pressing driving member 810, a pressing moving seat 811, a test tube rack pressing column 812, a test tube pressing column 813, and an elastic buffer 814. The pressing guide seat 809 is arranged near the moving track of the sample adding mechanism 700 and is oppositely distributed with the translation guide seat 801, i.e., the pressing guide seat 809 and the pressing moving seat 811 are respectively located on both sides of the moving track of the sample adding mechanism 700, and the test tube rack 701 of the sample adding mechanism 700 is located between the pressing guide seat 809 and the translation guide seat 801. The pressing driving member 810 can be a power element such as a motor or a pneumatic cylinder and is electrically connected with the controller 1300. The body of the pressing driving member 810 is installed on the pressing guide seat 809, and the power output end of the pressing driving member 810 is connected with the pressing moving seat 811 in a screw transmission or direct connection manner based on the specific type of the pressing driving member 810. At the same time, the pressing moving seat 811 is linearly and slidably connected with the pressing guide seat 809 (such as the form of guide rail + sliding groove).

[0092] Three elastic buffers 814 are installed in the pressing moving seat 811 side by side along the moving direction of the sample adding mechanism 700, and the test tube pressing column 813 is arranged on the pressing moving seat 811, one end of the test tube pressing column 813 is inserted into the pressing moving seat 811 and coaxially abuts against the elastic buffer 814 in the middle, and the test tube rack pressing column 812 is arranged on both sides of the test tube pressing column 813 along the moving direction of the sample adding mechanism 700, one end of the test tube rack pressing column 812 is inserted into the pressing moving seat 811 and coaxially abuts against the corresponding elastic buffer 814. When the sample adding mechanism 700 is stopped due to the second predetermined operation, the controller 1300 controls the pressing driving member 810 to drive the pressing moving seat 811 to move towards the test tube rack 701, so that the test tube rack pressing column 812 abuts against the test tube rack 701, and the test tube pressing column 813 abuts against the sample test tube B at the elution position f, so as to firmly clamp the sample test tube B between the translation guide seat 801 and the pressing moving seat 811, and due to the existence of the elastic buffer 814, the sample test tube B can be prevented from being pressed too tightly or too loosely, and the sample test tube B with different diameters and the test tube rack 701 with different tolerances can be self-adapted.

[0093] In one embodiment, referring to Figure 14 The test tube rack pressing column 812 and the test tube pressing column 813 are provided with strip-shaped limiting holes 815 distributed along the circumferential wall of the test tube rack pressing column 812 and the test tube pressing column 813 perpendicular to the extension direction of the elastic buffer 814 (or the moving direction of the pressing moving seat 811), and a limiting pin 816 is arranged in each strip-shaped limiting hole 815, the test tube rack pressing column 812 and the test tube pressing column 813 are installed in the pressing moving seat 811 in the form of insertion by means of the limiting pin 816, and due to the cooperation between the limiting pin 816 and the strip-shaped limiting hole 815, the moving stroke of the test tube rack pressing column 812 and the test tube pressing column 813 can be limited, the test tube rack pressing column 812 and the test tube pressing column 813 can be prevented from being separated from the pressing moving seat 811, and the test tube rack pressing column 812 and the test tube pressing column 813 can be prevented from being affected by the angle deflection when abutting against the test tube rack 701 and the sample test tube B, respectively.

[0094] Referring to Figure 1 , Figure 2 and Figure 5One embodiment provides a gynecological secretion detection device, which further includes a card holder mechanism 200. The card holder mechanism 200, the sample injection mechanism 300, and the detection mechanism are sequentially arranged on the outer periphery of the rotary conveyor mechanism 100 along the circumferential direction. Correspondingly, the functional position defined on the rotation trajectory of the rotary conveyor mechanism 100 also includes an upper card holder a. The card holder mechanism 200 is mainly used to store unused test cards A, and when the rotary conveyor mechanism 100 stops due to the addition of a test card, an unused test card A is added to the empty card holder located at the upper card holder a (i.e., the card holder rotated to the upper card holder a). In this embodiment, the card holder mechanism 200 mainly includes a card holder 201, a first loading platform 202, an upper card pusher assembly 203, and a card position detection component 204. The card holder 201 is a hollow structure with an opening at its lower end. The card holder 201 is mounted on the surface of the first loading platform 202 along the vertical direction (i.e., along the axial direction of the turntable conveyor mechanism 100), and the cross-sectional shape of the card holder 201 is adapted to the shape of the detection card to store unused detection cards A (detection cards A are stored in the card holder 201 in a stacked manner). A card outlet (not shown in the figure) is formed between the card holder 201 and the first loading platform 202, communicating with the lower opening of the card holder 201. The card outlet and the card position rotated to the upper card position a are located on the same straight line distributed along the radial direction of the turntable conveyor mechanism 100. Online, the card magazine mechanism 200 is aligned horizontally with the card slot a rotated to the upper card slot a. A card slot detection element 204 is mounted on the first loading platform 202 and close to the turntable conveyor mechanism 100. The card slot detection element 204 is electrically connected to the controller 1300 and is used to detect whether a detection card A exists on the card slot rotated to the upper card slot a. An upper card pusher assembly 203 is mounted on the first loading platform 202 and electrically connected to the controller 1300. When the turntable conveyor mechanism 100 stops due to the addition of a detection card, and the card slot detection element 204 detects that the corresponding card slot is empty, the controller 1300 controls the upper card pusher assembly 203 to push the detection card A stored in the card magazine 201 and located at the bottom layer to the corresponding card slot along the radial direction of the turntable conveyor mechanism 100 via the card outlet. In another embodiment, the card magazine mechanism 200 may also employ other existing devices with similar functions, existing in a structure that is fixedly aligned with the upper card slot a or movablely aligned with the upper card slot a, which will not be elaborated here.

[0095] In one embodiment, please refer to Figure 1 , Figure 2 and Figure 5two card storage mechanisms 200 are arranged on the outer periphery of the rotating disc conveying mechanism 100, and each of the card storage mechanisms 200 corresponds to an upper card position a. When the rotating disc conveying mechanism 100 is stopped due to the operation of adding detection cards, the controller 1300 controls one of the card storage mechanisms 200 to add detection cards A to the corresponding upper card position a and the empty card position, thereby forming a double card storage function, so that the two card storage mechanisms 200 are used as backup for each other. Compared with the configuration of one card storage mechanism 200, the problem of stopping the device due to the failure of the card storage mechanism 200, the lack of cards, the replenishment of detection cards, and the like can be effectively avoided, thereby creating conditions for improving the operation and detection efficiency of the device. Of course, according to the control requirements of the controller 1300 on the action time sequence of each mechanism, more than two card storage mechanisms 200 can also be arranged near the rotating track of the rotating disc conveying mechanism 100. In this embodiment, two card storage mechanisms 200 are taken as an example (for the convenience of distinction, one of the card storage mechanisms 200 is defined as a first card storage mechanism, and the other card storage mechanism is defined as a second card storage mechanism), and the two card storage mechanisms 200 can complete the operation of adding detection cards according to the following action process steps. Specifically, step 21 is to determine whether the state of the upper card position a is a card insertion state; if yes, step 22 is executed; if no, the waiting is queried. Step 22 is to determine whether the upper card buffer queue is empty; if yes, the waiting is queried; if no, step 23 is executed. Step 23 is to determine whether the first card storage mechanism or the second card storage mechanism is used; if the first card storage mechanism is used, step 24 is executed; if the second card storage mechanism is used, step 26 is executed. Step 24 is to execute the upper card action by the first card storage mechanism, and to determine whether the first card storage mechanism is in a cardless state; if yes, step 25 is executed; if no, step 28 is executed. Step 25 is to determine whether the second card storage mechanism is in a cardless fault in the fault list; if yes, it is reported that the first card storage mechanism and the second card storage mechanism are both in a cardless fault, the fault information is reported to the controller 1300, and the fault prompt is made; if no, the second card storage mechanism is switched to, and the next operation of adding detection cards is executed by the second card storage mechanism. Step 26 is to execute the upper card action by the second card storage mechanism, and to determine whether the second card storage mechanism is in a cardless state; if yes, step 25 is executed; if no, step 27 is executed. Step 27 is to determine whether the first card storage mechanism is in a cardless fault in the fault list; if yes, it is reported that the first card storage mechanism and the second card storage mechanism are both in a cardless fault, the fault information is reported to the controller 1300, and the fault prompt is made; if no, the first card storage mechanism is switched to, and the next operation of adding detection cards is executed by the first card storage mechanism. Step 28 is to determine whether the upper card action is completed; if yes, step 29 is executed; if no, the waiting is queried. Step 29 is to update the upper card state, update the upper card buffer information, and execute step 21 to form a cycle.

[0096] Please refer to Figure 4 and Figure 17One embodiment provides a gynecological secretion detection device, further comprising a detection mechanism 1500, and the controller 1300 defines a detection position h on the moving track of the sample feeding mechanism 700; the detection mechanism 1500 is located near the moving track of the sample feeding mechanism 700 and is electrically connected with the controller 1300; for the same sample, the controller 1300 controls the test tube station carrying the sample to pass through the detection position h, the elution position f and the sampling position g in sequence; when the sample feeding mechanism 700 stops due to the detection sample operation, the controller 1300 controls the detection mechanism 1500 to perform the detection sample operation, so as to use the detection mechanism 1500 to detect whether there is a sample (i.e. whether there is a sample test tube B containing the sample to be detected) in the test tube station moving to the detection position h, thereby providing a signal basis for whether the card loading mechanism 200 performs the detection card adding operation and whether the elution mechanism 800 and the sample feeding mechanism 300 perform corresponding operations when the test tube station moves to the elution position f or the sampling position g. Wherein, if there is a sample at the detection position h, when the carousel conveying mechanism 100 stops due to the first operation, the controller 1300 can control the card loading mechanism 200 to perform the detection card adding operation, so that each sample to be detected corresponds to a detection card A, preventing the detection card A on the carousel conveying mechanism 100 from being idle; if there is no sample at the detection position h, the sample feeding mechanism 700 continues to travel to determine whether there is a sample on the next test tube station, and if there is, the related mechanism performs the related operation, thereby ensuring that the detection device can continuously process multiple samples to be detected without interruption. In this embodiment, the detection mechanism 1500 can use sensing devices such as photoelectric sensors according to actual conditions.

[0097] Please refer to Figure 4 、 Figure 10 and Figure 11 One embodiment provides a gynecological secretion detection device, further comprising a code scanning mechanism 900, and the controller 1300 defines a code scanning position k on the moving track of the sample feeding mechanism 700; the code scanning mechanism 900 is located near the moving track of the sample feeding mechanism 700 and is electrically connected with the controller 1300, and for the same sample, the controller 1300 controls the test tube station carrying the sample to pass through the detection position h, the code scanning position k, the elution position f and the sampling position g in sequence; when the sample feeding mechanism 700 stops due to the information extraction operation, the controller 1300 controls the code scanning mechanism 900 to perform the information extraction operation, so as to use the code scanning mechanism 900 to extract information from the sample on the test tube station moving to the code scanning position k, thereby creating conditions for obtaining or retaining the information of the sample on the corresponding detection card A.

[0098] In one embodiment, please refer to Figure 10 and Figure 11The code scanning mechanism 900 mainly comprises a code scanning support 901, a code scanner 902, a friction wheel 903 and a friction driving member (such as a motor, not shown in the figure); wherein the code scanning support 901 is arranged at the side of the sample feeding mechanism 700 in the moving direction, the code scanner 902 is installed on the code scanning support 901 and located above the friction wheel 903, and the friction driving member is installed on the code scanning support 901 and connected with the friction wheel 903; when the sample feeding mechanism 700 stops due to the information extraction operation, the controller 1300 drives the friction wheel 903 to rotate around the vertical direction as the axis, so that the circumferential wall of the friction wheel 903 contacts with the circumferential wall of the sample test tube B moved to the code scanning position k, and the sample test tube B is driven to rotate synchronously by the friction contact effect between the two, at the same time, the controller 1300 controls the code scanner 902 to extract the information of the sample test tube B (such as the bar code attached to the sample test tube B and associated with the sample information), and the information extraction operation is realized.

[0099] Based on the sample feeding platform combination composed of the sample feeding mechanism 700, the elution mechanism 800, the detection mechanism 1500 and the code scanning mechanism 900, the operation of preparing the sample can be completed according to the following action flow steps, specifically: step 71, judging whether the test tube rack 701 exists; if yes, executing step 72; if no, ending the detection task. Step 72, the linear transmission assembly 702 executes the test tube rack 701 conveying action, and judges whether the test tube rack 701 reaches the predetermined initial position; if yes, executing step 73; if no, reporting the fault information to the controller 1300, and continuing to execute after the fault is eliminated. Step 73, the detection mechanism 1500 executes the sample detection action, and judges whether the sample test tube B exists; if yes, executing step 74; if no, querying the waiting. Step 74, updating the sample test tube information, adding the detection card A to the card position, and judging whether the test tube rack 701 reaches the predetermined end position; if yes, executing step 77; if no, executing step 75. Step 75, judging whether the sample test tube B exists in the code scanning position k, the elution position f and the sampling position g; if yes, executing step 76; if no, querying the waiting. Step 76, the code scanning mechanism 900 executes the information extraction action, the elution mechanism 800 executes the dilution and elution action, and the sample feeding mechanism 300 executes the sample sucking action, and judging whether the execution is successful; if yes, updating the task information, and executing step 73; if no, reporting the fault information to the controller 1300, and continuing to execute after the fault is eliminated. Step 77, judging whether the waste sample area is full; if yes, reporting the fault information to the controller 1300 and making the fault prompt; if no, pushing the test tube rack 701 into the waste sample area, and executing step 78. Step 78, updating the information, and executing step 71.

[0100] In other embodiments, the foregoing embodiments can also be flexibly arranged on the outer periphery of the carousel conveying mechanism 100 (correspondingly, the upper card position a, the sample adding position b, the microscope examination position c, the color development position d, and the photographing position e are defined on the rotation track of the carousel conveying mechanism 100 according to the specific positions of the corresponding mechanisms). At this time, the controller 1300 can control the forward and reverse rotation of the carousel conveying mechanism 100, so that the card positions pass through the upper card position a, the sample adding position b, the microscope examination position c, the color development position d, and the photographing position e in turn, thereby completing the corresponding operation tasks under the cooperation of the related mechanisms.

[0101] Referring to Figure 18 Based on the overall structural layout of the gynecological secretion detection device provided in the present application and the cooperation relationship between the mechanisms, the following process and control flow can be used to complete the complete detection task of the gynecological secretion sample. Taking the detection process of the same sample as an example:

[0102] 1. Sample adding process: The sample test tube B containing the sample to be detected is driven by the sample sending mechanism 700 to pass through the detection position h, the code scanning position k, the elution position f, and the sampling position g in sequence, and the detection mechanism 1500 performs a detection sample operation at the detection position h to determine whether the sample to be detected exists on the test tube station corresponding thereto, the code scanning mechanism 900 performs an information extraction operation at the code scanning position k to determine the information of the sample to be detected on the test tube station corresponding thereto, the elution mechanism 800 performs a dilution and elution operation at the elution position f to dilute and elute the sample to be detected on the test tube station corresponding thereto and stir and mix, and the sample adding mechanism 300 performs a sample sucking operation at the sampling position g to suck the sample to be detected from the sample test tube B on the test tube station corresponding thereto. First, a part of the sample to be detected is added to the dry chemical area of the detection card A on the card position rotated to the sample adding position b, and then the remaining part of the sample to be detected is added to the sample reaction mechanism 1400 for dyeing. The turbidity (or turbidity) of the part of the sample to be detected is detected in the sample reaction mechanism 1400. After the sample turbidity is less than or equal to the threshold turbidity and the sample dyeing is qualified, the sample adding mechanism 300 sucks the part of the sample to be detected from the sample reaction mechanism 1400 and adds the part of the sample to be detected to the microscope examination area of the detection card A on the card position rotated to the sample adding position b. After the elution mechanism 800 and the sample adding mechanism 300 complete the related operations of one sample, they are moved to the cleaning mechanism for cleaning, so as to prepare for the same operation of the next sample.

[0103] 2、Detection process: the detection card for carrying the sample to be detected is placed in the rotating action of the rotating disc conveying mechanism 100, and is circulated through the card position a, the sample adding position b, the microscope examination position c, the color developing position d and the photographing position e in turn. After the detection mechanism 1500 performs the detection sample operation in the detection position h and determines that the sample to be detected exists in the test tube position corresponding thereto, the card warehouse mechanism 200 performs the adding detection card operation in the card position a to add the detection card A to the card position corresponding thereto, so as to realize the association of the detection card A and the sample to be detected. The sample adding mechanism 300 performs the adding sample operation in the sample adding position b to add a part of the sample to be detected which is diluted, eluted, stirred and mixed to the dry chemical area of the detection card A in the card position corresponding thereto, and adds another part of the sample to be detected which is diluted, eluted, turbidity detected and dyed to the microscope examination area of the detection card A. The microscope examination mechanism 400 performs the microscope examination scanning operation in the microscope examination position c to perform the microscope examination scanning on the detection card A in the card position corresponding thereto and the sample to be detected in the microscope examination area of the detection card A. The color developing mechanism 500 performs the adding color developing agent operation in the color developing position d to add the color developing agent to the sample to be detected in the dry chemical area of the detection card A in the card position corresponding thereto. The photographing mechanism 600 performs the photographing operation in the photographing position e to perform the photographing on the sample to be detected in the dry chemical area of the detection card A, and finally performs the card discarding treatment on the detection card A (specifically, first transferring the detection card A from the card position corresponding to the photographing position e to the photographing mechanism 600, and then performing the card discarding treatment after the photographing is completed).

[0104] 3、Based on the cooperation of the sample adding process and the detection process, the rotating disc conveying mechanism 100, the card warehouse mechanism 200, the sample adding mechanism 300, the microscope examination mechanism 400, the color developing mechanism 500, the photographing mechanism 600 and the incubation mechanism 1000 are combined into a rotating disc platform for realizing the tasks of adding card, adding sample, microscope examination, incubation, adding color developing agent, photographing and card discarding. The detection mechanism 1500, the code scanning mechanism 900, the elution mechanism 800, the cleaning mechanism, the sample reaction mechanism 1400 and the sample adding mechanism 300 are combined into a sample conveying platform for realizing the tasks of sample test tube detection, code scanning, elution dilution stirring, sample dyeing, sample turbidity detection, sample sucking and cleaning. Thus, the controller 1300 can be used to coordinately control the rotating disc platform and the sample conveying platform to automatically realize the complete detection process of the same sample and the cyclic continuous detection of multiple samples.

[0105] Firstly, although the operation tasks of the rotating disc platform and the operation tasks of the sample conveying platform complement each other, they will not be affected by each other, and each mechanism can independently use an independent control thread to complete the operation, which can effectively reduce the dependency between part of the operation tasks, improve the operation and detection efficiency of the detection device, and ensure the stable operation of the device and reduce the failure rate.

[0106] Secondly, the layout of each mechanism is centered on the rotary table type conveying mechanism 100, which can effectively reduce the structural volume of the entire device, reduce the occupied space, and create favorable conditions for the miniaturization and compact design of the device.

[0107] The above application of specific examples to the present application is described, which is only used to help understand the present application, and does not limit the present application. For those skilled in the art to which the present application belongs, according to the idea of the present application, a number of simple deductions, deformations or substitutions can be made.

Claims

1. A sample delivery device, characterized by, The application relates to a sample injection mechanism, a sample reaction mechanism and a sample delivery mechanism. The sample injection mechanism is controlled to move along a first direction, and a plurality of functional positions are defined along the movement track of the sample injection mechanism, wherein the plurality of functional positions include a sampling position and a reaction position. The sample reaction mechanism is arranged at the reaction position, so that the sample injection mechanism sucks the sample to be detected at the sampling position, and the sample to be detected is delivered to the reaction position and added to the sample reaction mechanism in the first direction. The sample reaction mechanism includes a reaction container for containing the sample to be detected, a turbidity detector arranged at the outer circumferential side of the reaction container and used for detecting the turbidity of the sample to be detected, and a reagent adding pipe extending into the reaction container and used for adding a reaction reagent into the reaction container.

2. The sample delivery device of claim 1, wherein The reagent adding pipe includes a diluent adding pipe, which injects diluent into the reaction container when the turbidity of the sample to be detected detected by the turbidity detector is greater than a turbidity threshold, so that the turbidity of the sample to be detected is finally less than or equal to the turbidity threshold.

3. A gynecological discharge detection device, characterized in that, The sample delivery mechanism is defined with a sample adding position along the delivery direction of the sample delivery mechanism, and the sampling position, the reaction position and the sample adding position are arranged in sequence in the first direction, so that the sample injection mechanism delivers the sample to be detected to the sample adding position and adds the sample to the sample delivery mechanism in the first direction. The application further relates to a cleaning mechanism, and the functional positions further include a cleaning position. The sampling position, the cleaning position, the reaction position and the sample adding position are arranged in sequence in the first direction, and the cleaning mechanism is arranged at the cleaning position, so that the sample injection mechanism is cleaned after adding the sample to be detected to the sample delivery mechanism. The application relates to a sample injection mechanism, a sample reaction mechanism and a sample delivery mechanism. The sample injection mechanism is controlled to move along a first direction, and a plurality of functional positions are defined along the movement track of the sample injection mechanism, wherein the plurality of functional positions include a sampling position and a reaction position. The sample reaction mechanism is arranged at the reaction position, so that the sample injection mechanism sucks the sample to be detected at the sampling position, and the sample to be detected is delivered to the reaction position and added to the sample reaction mechanism in the first direction. The sample reaction mechanism includes a reaction container for containing the sample to be detected, a turbidity detector arranged at the outer circumferential side of the reaction container and used for detecting the turbidity of the sample to be detected, and a reagent adding pipe extending into the reaction container and used for adding a reaction reagent into the reaction container. The reagent adding pipe includes a diluent adding pipe, which injects diluent into the reaction container when the turbidity of the sample to be detected detected by the turbidity detector is greater than a turbidity threshold, so that the turbidity of the sample to be detected is finally less than or equal to the turbidity threshold. The sample delivery mechanism is defined with a sample adding position and a detection position along the delivery direction of the sample delivery mechanism, the sampling position, the reaction position and the sample adding position are arranged in sequence in the first direction, and the sample adding position and the detection position are arranged in sequence along the delivery direction of the sample delivery mechanism, so that the sample injection mechanism delivers the sample to be detected to the sample adding position and adds the sample to the sample delivery mechanism in the first direction, and then the sample delivery mechanism delivers the sample to be detected from the sample adding position to the detection position. And a detection mechanism, the detection mechanism is used for detecting the gynecological item of the sample to be detected when the conveying mechanism conveys the sample to be detected to the detection position.

4. The gynecological discharge detection device of claim 3, wherein, The conveying mechanism is a rotating disc conveying mechanism, the rotating disc conveying mechanism is controllable to rotate, the sample adding position and the detection position are arranged along a rotation track of the rotating disc conveying mechanism, and the detection mechanism and the sample adding mechanism are arranged along a circumferential direction of the rotating disc conveying mechanism. A plurality of sample detection cards are arranged on the rotating disc conveying mechanism along the circumferential direction, and the sample adding mechanism conveys the sample to be detected to the sample adding position in the first direction and adds the sample to the sample detection card.

5. The gynecological discharge detection device of claim 4, wherein the absorbent material is a hydrogel. The sample conveying mechanism is further provided, and the sample conveying mechanism is controllable to move along a second direction and is used for conveying the sample to be detected to the sampling position.

6. The gynecological discharge detection device of claim 5, wherein, The detection mechanism and the card storage mechanism are further provided, a detection position is defined on a movement track of the sample conveying mechanism, an upper card position is defined on a rotation track of the rotating disc conveying mechanism, the detection position and the sampling position are arranged along the movement track of the sample conveying mechanism, and the upper card position, the sample adding position and the detection position are arranged along the rotation track of the rotating disc conveying mechanism. The detection mechanism is arranged on a side of the sample conveying mechanism along the second direction and is used for detecting whether the detection position has the sample to be detected. The card storage mechanism is arranged along the circumferential direction of the rotating disc conveying mechanism and is used for adding the detection card from the upper card position to the rotating disc conveying mechanism when the detection mechanism detects that the detection position has the sample to be detected. The card storage mechanism, the sample adding mechanism and the detection mechanism are arranged along the circumferential direction of the rotating disc conveying mechanism.

7. The gynecological discharge detection device of claim 3, wherein the absorbent pad is a hydrophilic pad. The detection card is carried on the conveying mechanism, and the detection card has a dry chemical area and a microscope area. The sample adding mechanism is used for adding a first part of the sample to be detected to the dry chemical area of the detection card and adding a second part of the sample to be detected to the sample reaction mechanism when the conveying mechanism conveys the detection card to the sample adding position, and then adding the reacted sample to be detected to the microscope area of the detection card. The detection mechanism is used for detecting the gynecological item of the sample to be detected in the dry chemical area and the microscope area of the detection card when the conveying mechanism conveys the detection card to the detection position.

8. The gynecological discharge detection device of claim 7, wherein, The detection mechanism comprises a microscope mechanism and a photographing mechanism arranged along a conveying direction of the conveying mechanism in sequence, and the detection position comprises a microscope position and a photographing position. The microscope mechanism is used for moving the detection card out of the conveying mechanism when the conveying mechanism conveys the detection card to the microscope position, and moving the detection card into the conveying mechanism after completing microscope scanning of the sample to be detected in the microscope area of the detection card. The photographing mechanism is used for moving the detection card out of the conveying mechanism when the conveying mechanism conveys the detection card to the photographing position, and photographing the sample to be detected in the dry chemical area of the detection card.

9. The gynecological discharge detection device of claim 8, wherein, The incubation mechanism is further provided, and the incubation mechanism is arranged opposite to the conveying mechanism and is used for heating the sample to be detected on the conveying mechanism to keep the temperature of the sample to be detected in a preset range. The detection mechanism further comprises a color developing mechanism, the microscope mechanism, the color developing mechanism and the photographing mechanism are sequentially arranged along the conveying direction of the conveying mechanism, the detection position further comprises a color developing position, the sample adding position, the microscope mechanism, the color developing position and the photographing position are sequentially arranged along the conveying direction of the conveying mechanism; The color developing mechanism is configured to add a color developing agent to the dry chemical area of the detection card when the conveying mechanism conveys the detection card completing the microscope scanning to the color developing position.

Images