Film viewing equipment and methods
By designing a slide reading device that includes sample introduction, flipping, and clamping mechanisms, and utilizing flipping control and clamping operations at different speeds, the problem of sample slides sliding or slipping out during the flipping process of the slide basket was solved, ensuring the stability and integrity of the sample slides.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SHENZHEN REETOO BIOTECHNOLOGY CO LTD
- Filing Date
- 2022-05-31
- Publication Date
- 2026-06-30
AI Technical Summary
During the flipping of the slide basket, the sample slides are prone to sliding or slipping out, which can lead to damage.
A slide reading device was designed, including a sample feeding device, a flipping device, and a clamping device. By controlling the flipping device to flip the slide basket at different speeds, combined with the clamping operation of the clamping device, the stability of the slide basket during the flipping process is ensured.
This effectively prevents the slide from sliding or slipping out during the flipping process, thus protecting the integrity of the sample slide.
Smart Images

Figure CN114942336B_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of medical devices, and more particularly to a film reading device and a film reading method. Background Technology
[0002] Currently, people often prepare sample slides from cell samples to be tested. In order to facilitate batch processing of sample slides, the prepared sample slides are often loaded into slide baskets from top to bottom so that the sample slides can be stored or transported in batches through the slide baskets.
[0003] However, when examining the sample slides in the slide basket, the slide basket needs to be rotated at a preset angle to facilitate the handling of the sample slides. However, during the rotation process, the rotation speed is difficult to control, which can easily cause the sample slides to slide in the slide basket or even slide out of the slide basket, resulting in damage to the sample slides. Summary of the Invention
[0004] This application provides a slide reading device, which aims to solve the problem that in existing slide reading devices, the sample slides are easily allowed to slide in or out of the slide basket during the flipping process.
[0005] In a first aspect, this application provides a film viewing device, comprising:
[0006] Sample delivery device, used to transport a slide basket loaded with glass slides;
[0007] A flipping device is used to receive the slide basket transported by the sample introduction device and flip the slide basket.
[0008] A clamping device is used to clamp the target slide from the flipped slide basket and transfer the target slide to the reading position to perform the corresponding reading operation;
[0009] The controller is configured to, after the flipping device receives the slide basket, control the flipping device to perform a first flipping operation on the slide basket, so as to drive the slide basket to flip at a first speed;
[0010] When the glass slide basket reaches the preset first angle, the control flipping device performs a second flipping operation on the glass slide basket to drive the glass slide basket to flip to the preset angle at a second speed, wherein the second speed is less than the first speed.
[0011] Optionally, the flipping device is used to flip the slide basket from a first state with an upward opening to a second state with a side opening, wherein the slide basket transported by the sample injection device is in the first state with an upward opening, and when the slide basket is flipped to a preset angle, the slide basket is in the second state with a side opening.
[0012] Optionally, the first angle is 30°-60°, and the preset angle is 85°-95°.
[0013] Optionally, the flipping device is also used to drive the flipped slide basket to move up and down, so that the clamping device can switch to clamp the target slide loaded in the slide basket.
[0014] Optionally, the flipping device includes:
[0015] The receiving assembly has a receiving cavity for receiving a slide basket, and the receiving cavity has a receiving opening for the slide basket to enter and exit.
[0016] The rotating component is used to drive the receiving component to rotate so as to rotate the slide basket contained in the receiving cavity.
[0017] Optionally, the sample introduction device includes:
[0018] Sample introduction track;
[0019] A transfer assembly for moving a slide basket along a sample inlet track so that the slide basket is transferred from the accommodating opening to the flipping device.
[0020] Optionally, the controller is also configured to:
[0021] After flipping the slide basket, the control clamping device picks up the target slide from the slide basket and moves the target slide a first distance away;
[0022] After the target slide has moved a first distance, the clamping device is controlled to release the clamping of the target slide, and the clamping device is controlled to pick up the target slide from the slide basket and remove the target slide from the slide basket.
[0023] Optionally, the clamping device includes a first clamping assembly and a second clamping assembly that cooperates with the first clamping assembly to clamp the target glass slide. The first clamping assembly includes a first clamping arm and a first clamping member connected to the first clamping arm and at least partially exposed in the first clamping arm. The second clamping assembly includes a second clamping arm movably connected to the first clamping arm and a second clamping member connected to the second clamping arm and at least partially exposed in the second clamping arm.
[0024] The controller controls the first clamping member and the second clamping member to cooperate in clamping the target glass slide and moving the target glass slide out of the first distance, and / or controls the first clamping arm and the second clamping arm to cooperate in clamping the target glass slide and moving the target glass slide out of the slide basket.
[0025] Optionally, the thickness of the first clamping member and the second clamping member in the first direction is less than the thickness of the first clamping arm and the second clamping arm in the first direction, where the first direction is the direction in which the second clamping member and the first clamping member move away from or towards each other and undergo relative displacement.
[0026] Secondly, this application also provides a method for viewing images, applied to the image viewing device disclosed in any embodiment of this application, the method comprising:
[0027] Control the sample delivery device to transport the slide basket loaded with glass slides;
[0028] The control flipping device receives the slide basket transported by the sample introduction device and performs a first flipping operation on the slide basket to drive the slide basket to flip at a first speed;
[0029] When the flipping angle of the slide basket reaches the preset first angle, the control flipping device performs a second flipping operation on the slide basket to drive the slide basket to flip to the preset angle at a second speed, wherein the second speed is less than the first speed;
[0030] The control clamping device picks up the target slide from the flipped slide basket and moves the target slide to the reading position to perform the corresponding reading operation.
[0031] This application provides a slide reading device and a slide reading method. The slide reading device includes a sample feeding device, a flipping device, a clamping device, and a controller. The sample feeding device is used to transport a slide basket loaded with slides. The flipping device is used to receive the slide basket transported by the sample feeding device and flip the slide basket. The clamping device is used to clamp a target slide from the flipped slide basket and transfer the target slide to the reading position to perform the corresponding reading operation. The controller is configured to, after the flipping device receives the slide basket, control the flipping device to perform a first flipping operation on the slide basket to drive the slide basket to flip at a first speed. When the flipping angle of the slide basket reaches a preset first angle, control the flipping device to perform a second flipping operation on the slide basket to drive the slide basket to flip at a second speed to a preset angle. The second speed is less than the first speed, thereby avoiding the sample slide from sliding in or out of the slide basket during the flipping process, which could lead to damage to the sample slide.
[0032] It should be understood that the above general description and the following detailed description are exemplary and explanatory only, and do not limit the disclosure of the embodiments of this application. Attached Figure Description
[0033] To more clearly illustrate the technical solutions in the embodiments of this application, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0034] Figure 1 A block diagram of a module structure of a film reading device provided in an embodiment of this application;
[0035] Figure 2 A schematic diagram of the sample feeding device and flipping device of a film reading device provided in an embodiment of this application;
[0036] Figure 3 This is a schematic diagram of the structure of a flipping device and a clamping device for a film reading device provided in an embodiment of this application;
[0037] Figure 4 This is a schematic diagram of the structure of a microscopic examination device for a film reading equipment provided in an embodiment of this application;
[0038] Figure 5 This is a schematic diagram of the structure of a flipping device for a film reading device provided in an embodiment of this application;
[0039] Figure 6 A schematic diagram of the structure of a transfer component of a film reading device provided in an embodiment of this application;
[0040] Figure 7 This is a schematic diagram of the structure of a clamping device for a film reading device provided in an embodiment of this application;
[0041] Figure 8 This is an exploded structural diagram of a clamping device for a film reading device provided in an embodiment of this application;
[0042] Figure 9 This is a schematic flowchart of the image reading method provided in the embodiments of this application;
[0043] Figure label:
[0044] 100. Film viewing equipment; 10. Sample injection device; 11. Sample injection track;
[0045] 12. Transfer assembly; 121. Transfer drive component; 122. Transfer transmission component;
[0046] 123. Push claw; 13. Claw guide rail; 20. Tilting device;
[0047] 21. Receiving assembly; 211. First clamping plate; 212. Second clamping plate;
[0048] 213. Connecting plate; 214. Receiving cavity; 215. First positioning part;
[0049] 22. Rotating assembly; 23. Lifting assembly; 231. Lifting drive component;
[0050] 232. Lifting transmission components; 233. Guide seat; 234. Lifting guide rail;
[0051] 24. Optical sensor; 30. Clamping device; 31. First clamping assembly;
[0052] 311. First clamping arm; 312. First clamping component; 32. Second clamping assembly;
[0053] 321. Second clamping arm; 322. Second clamping component; 40. Controller;
[0054] 50. Microscopic examination device; 51. Image acquisition device; 52. Oil dripping device;
[0055] 200. Sample slide; 201. Target slide; 300. Slide basket; 301. Slide inlet. Detailed Implementation
[0056] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.
[0057] Currently, cell samples to be tested are often prepared into sample slides. To facilitate batch processing, the prepared sample slides are usually loaded into slide baskets from top to bottom for batch storage or transport. However, when reviewing the sample slides in the slide basket, the basket needs to be rotated at a preset angle for easy handling. During this rotation, the speed is difficult to control, which can cause the sample slides to slide within the basket or even slip out, resulting in damage. Therefore, this application provides a slide reading device.
[0058] The following detailed description of some embodiments of this application is provided in conjunction with the accompanying drawings. Unless otherwise specified, the following embodiments and features can be combined with each other.
[0059] Please see Figures 1 to 3 , Figure 1 This is a block diagram of a module structure of a film reading device provided in an embodiment of this application. Figure 2 This is a schematic diagram of the sample feeding device and the flipping device of a film reading device provided in an embodiment of this application. Figure 3 This is a schematic diagram of the flipping device and clamping device of a film reading device provided in an embodiment of this application.
[0060] like Figures 1 to 3As shown, the slide reading device 100 includes a sample feeding device 10, a flipping device 20, a clamping device 30, and a controller 40. The sample feeding device 10 transports a slide basket 300 containing slides. The flipping device 20 receives the slide basket 300 transported by the sample feeding device 10 and flips it. The clamping device 30 clamps a target slide 201 from the flipped slide basket 300 and transfers the target slide 201 to the reading position to perform the corresponding reading operation. The controller 40 is electrically connected to the sample feeding device 10, the flipping device 20, and the clamping device 30 to control their operation. The controller 40 is configured to... After receiving the slide basket 300, the device 20 controls the flipping device 20 to perform a first flipping operation on the slide basket 300, so as to drive the slide basket 300 to flip at a first speed. When the flipping angle of the slide basket 300 reaches a preset first angle, the device 20 controls the flipping device 20 to perform a second flipping operation on the slide basket 300, so as to drive the slide basket 300 to flip at a second speed to a preset angle. The second speed is less than the first speed, so that when the slide basket 300 is flipped, it is fast at first and then slows down. This does not affect the flipping speed of the slide basket 300, and also avoids the sample slide 200 from sliding in or out of the slide basket 300 during the flipping process, which would cause damage to the sample slide 200.
[0061] It should be understood that the sample slide 200 includes the target slide 201, which is at least one of several sample slides 200. The target slide 201 is generally stored together with the other sample slides 200, for example, by storing the target slide 201 and other sample slides 200 alternately in a preset slide basket 300. The following description uses the example of storing the target slide 201 and other sample slides 200 in the slide basket 300 to illustrate the structure and workflow of each component of the slide reading device 100.
[0062] Specifically, the slide reading device 100 has a preset flip position, and the flipping device 20 is set accordingly. When the slide reading device 100 performs a slide reading operation on the target slide 201, the controller 40 first controls the sample feeding device 10 to transport the slide basket 300 containing the target slide 201 to the flip position, and then controls the flipping device 20 to receive the slide basket 300 transported to the flip position and flip the slide basket 300. The clamping device 30 is used to clamp the target slide 201 from the flipped slide basket 300. After the flipping device 20 receives the slide basket 300, the controller 40 controls the flipping device 20 to perform the first... The flipping operation drives the slide basket 300 to flip at a first speed. When the flipping angle of the slide basket 300 reaches a preset first angle, the controller 40 controls the flipping device 20 to perform a second flipping operation on the slide basket 300, so as to drive the slide basket 300 to flip at a second speed to a preset angle, wherein the second speed is less than the first speed. After this, the controller 40 controls the clamping device 30 to clamp the target slide 201 from the flipped slide basket 300 and transfer the target slide 201 to the reading position to perform the corresponding reading operation.
[0063] In some embodiments, the flipping device 20 is used to flip the slide basket 300 from a first state with an upward opening to a second state with a side opening, wherein the slide basket 300 transported by the sample feeding device 10 is in the first state with an upward opening, and when the slide basket 300 is flipped to a preset angle, the slide basket 300 is in the second state with a side opening.
[0064] It should be understood that the slide basket 300 is provided with a slide inlet 301. The target slide 201 and other sample slides 200 are loaded into the slide basket 300 through the slide inlet 301. The slide basket 300 transported by the sample introduction device 10 is in a first state with the slide inlet 301 facing upwards. The clamping device 30 is used to clamp the target slide 201 from the side-opening slide basket 300 and transfer the target slide 201 to the reading position to perform the corresponding reading operation. Therefore, before controlling the clamping device 30 to clamp the target slide 201 from the slide basket 300, the slide basket 300 needs to be in a second state with a side opening so that the clamping device 30 can smoothly clamp the target slide 201 from the side-opening slide basket 300.
[0065] Specifically, controller 40 controls flipping device 20 to receive signals from the device in the following position: Figure 2 The slide basket 300, with the slide inlet opening 301 facing upwards, is first controlled by the flipping device 20 to flip the slide basket 300 at a first speed. When the flipping angle of the slide basket 300 reaches the first angle, the flipping device 20 is controlled to flip the slide basket 300 at a second speed less than the first speed to a preset angle, so that the slide basket 300 is in the position shown. Figure 3In the second state of the lateral opening shown, the clamping device 30 is then controlled to smoothly clamp the target slide 201 from the slide basket 300 with the lateral opening.
[0066] In some embodiments, the first angle is 30°-60°, and the preset angle is 85°-95°. It should be understood that the preset angle is 85°-95°, that is, the flipping device 20 is used to flip the slide basket 300 from the vertically upward state of the slide inlet 301 to the horizontal state of the opening, so that the clamping device 30 can horizontally clamp and remove the target slide 201 from the side-opening slide basket 300.
[0067] Specifically, taking a first angle of 60° and a preset angle of 90° as an example: During the flipping process of the slide basket 300, the controller 40 controls the flipping device 20 to perform a first flipping operation on the slide basket 300, so as to drive the slide basket 300 to flip at a first speed. When the flipping angle of the slide basket 300 reaches 60°, the controller 40 controls the flipping device 20 to perform a second flipping operation on the slide basket 300, so that the slide basket 300 flips another 30° at a second speed, so that the flipping angle of the slide basket 300 reaches the preset angle of 90°, wherein the second speed is less than the first speed.
[0068] For example, the first speed can be one revolution per second and the second speed can be half a revolution per second, so that when the flipping device 20 flips the slide basket 300, it is fast at first and then slows down, which does not affect the flipping speed and prevents the sample slide 200 from sliding in or out of the slide basket 300.
[0069] The slide reading device 100 provided in this embodiment first controls the flipping device 20 to drive the slide basket 300 to flip at a first speed. When the flipping angle of the slide basket 300 reaches the first angle, the flipping device 20 is then controlled to drive the slide basket 300 to flip at a second speed less than the first speed to a preset angle. This avoids the sample slide 200 from sliding in or out of the slide basket 300 during the flipping process of the slide reading device 100, which could lead to damage to the sample slide 200.
[0070] Please see Figure 4 , Figure 4 This is a schematic diagram of the structure of a microscopic examination device for a film reading equipment provided in an embodiment of this application.
[0071] like Figure 4As shown, the slide reading device 100 further includes a microscopic inspection device 50 corresponding to the slide reading position. The microscopic inspection device 50 is used to perform a preset microscopic inspection operation on the target slide 201 transferred to the slide reading position to complete the corresponding slide reading operation. The microscopic inspection device 50 includes at least an image acquisition device 51. The image acquisition device 51 is used to acquire images of the target slide 201 to complete the corresponding slide reading operation. The image acquisition device 51 includes, but is not limited to, a combination of a camera and a lens group.
[0072] Furthermore, the microscopic examination device 50 also includes an oil-drip device 52, which is used to perform a preset oil-drip operation on the target slide 201 so that at least part of the surface of the target slide 201 is covered with immersion oil, thereby improving the acquisition quality of the image of the target slide 201 acquired by the image acquisition device 51. The image acquisition device 51 is used to acquire images of the target slide 201 with or without immersion oil to complete the corresponding slide reading operation.
[0073] Specifically, the slide reading device 100 is equipped with preset oil-spraying positions and microscopic examination positions. The image acquisition device 51 and the oil-spraying device 52 are respectively set for the oil-spraying positions and microscopic examination positions. The controller is configured to control the clamping device 30 to clamp the target slide 201 from the side-opening slide basket 300 and move the target slide 201 to the oil-spraying position. After the target slide 201 is moved to the oil-spraying position, the controller controls the oil-spraying device 52 to perform an oil-spraying operation on the target slide 201 so that at least part of the surface of the target slide 201 is covered with immersion oil. The controller moves the target slide 201 to the microscopic examination position and controls the image acquisition device 51 to acquire an image of the target slide 201 with the surface covered with immersion oil to complete the corresponding slide reading operation.
[0074] Please see Figure 5 , Figure 5 This is a schematic diagram of the structure of a flipping device for a film reading device provided in an embodiment of this application.
[0075] like Figures 2 to 5 As shown, in some embodiments, the flipping device 20 includes a receiving component 21 and a rotating component 22, wherein the receiving component 21 forms a receiving cavity 214 for receiving the slide basket 300, and the receiving cavity 214 has a receiving opening for the slide basket 300 to enter and exit, and the rotating component 22 is used to drive the receiving component 21 to flip so as to drive the slide basket 300 received in the receiving cavity 214 to flip.
[0076] Specifically, the receiving component 21 is connected to the output end of the rotating component 22, and the controller 40 is configured to control the rotating component 22 to drive the output end of the rotating component 22 to move after the receiving component 21 receives the slide basket 300 transported by the sample introduction device 10, so as to cause the receiving component 21 connected to the output end of the rotating component 22 and the slide basket 300 contained in the receiving component 21 to rotate.
[0077] For example, the rotating component 22 includes, but is not limited to, a motor, and the receiving component 21 is connected to the output end of the motor and rotates with the rotation of the output end of the motor.
[0078] In some embodiments, the slide reading device 100 is provided with a rotation sensor connected to the rotation assembly 22, and the controller 40 is electrically connected to the rotation sensor. The rotation sensor is used to sense the angle at which the rotation assembly 22 drives the receiving assembly 21 to rotate to generate a corresponding electrical signal, and sends the electrical signal to the controller 40 so that the controller 40 can determine whether the rotation angle of the slide basket 300 has reached a first angle or a preset angle based on the electrical signal.
[0079] In some other embodiments, the slide reading device 100 is provided with an optical sensor 24, and the controller 40 is electrically connected to the optical sensor 24. The optical sensor 24 is used to sense the angle at which the rotating component 22 drives the receiving component 21 to flip, so as to generate a corresponding electrical signal and send the electrical signal to the controller 40, so that the controller 40 can determine whether the flip angle of the slide basket 300 has reached a first angle or a preset angle based on the electrical signal. The optical sensor 24 includes, but is not limited to, an optical coupler or an optical imaging component.
[0080] It should be noted that the slide reading device 100 can implement either of the two methods: sensing the angle of rotation of the rotating component 22 to drive the receiving component 21 to flip by a rotation sensor, or sensing the angle of rotation of the rotating component 22 to drive the receiving component 21 to flip by an optical sensor 24. They can be implemented separately or together. That is, the flip angle of the slide basket 300 is determined by the sensing result of the rotation sensor and the detection result of the optical sensor 24.
[0081] In some embodiments, the receiving component 21 includes a first clamping plate 211, a second clamping plate 212, and a connecting plate 213. The first clamping plate 211 is connected to the output end of the rotating component 22, the second clamping plate 212 is spaced apart from the first clamping plate 211, and the connecting plate 213 connects the first clamping plate 211 and the second clamping plate 212. The first clamping plate 211, the second clamping plate 212, and the connecting plate 213 cooperate to form a receiving cavity 214.
[0082] Specifically, the controller 40 is configured to control the rotating assembly 22 to drive the output end of the rotating assembly 22 to move after the receiving assembly 21 receives the slide basket 300 transported by the sample introduction device 10, so as to drive the first clamping plate 211 connected to the output end of the rotating assembly 22 to rotate, and drive the receiving assembly 21 and the slide basket 300 contained in the receiving cavity 214 to flip.
[0083] In some embodiments, at least one of the first clamping plate 211 and the second clamping plate 212 is provided with a first positioning part 215, and the outer wall of the slide basket 300 is provided with a second positioning part for detachably engaging with the first positioning part 215. The slide reading device 100 provided in this application, through the detachable engagement of the first positioning part 215 and the second positioning part, ensures that the slide basket 300 is tightly clamped within the receiving cavity 214, thereby improving the firmness of the receiving assembly 21 in accommodating the slide basket 300 and the stability of the flipping device 20 in flipping the slide basket 300.
[0084] In some embodiments, the flipping device 20 is also used to drive the flipped slide basket 300 to move up and down, so that the clamping device 30 can switch to clamp the target slide 201 loaded in the slide basket 300.
[0085] It should be understood that the sample slide 200 loaded in the slide basket 300 includes at least one target slide 201. After being flipped, the slide basket 300 is in a second state with a side opening. The target slide 201 to be clamped is opposite to the clamping port of the clamping device 30. The clamping device 30 clamps the target slide 201 opposite to the clamping device 30 from the side-opening slide basket 300. When it is necessary to switch the target slide 201, the flipping device 20 drives the flipped slide basket 300 to perform a lifting and lowering movement to switch the position of the slide basket 300 relative to the clamping device 30 and switch the target slide 201 opposite to the clamping port of the clamping device 30, so that the clamping device 30 can switch the target slide 201 to be clamped.
[0086] Specifically, the flipping device 20 also includes a lifting component 23, which is connected to the rotating component 22 and is used to drive the rotating component 22 to perform lifting and lowering movements, so as to drive the receiving component 21 and the slide basket 300 contained in the receiving component 21 to perform lifting and lowering movements, so that the slide basket 300 moves to a position that is convenient for the clamping device 30 to clamp the target slide 201, and also enables the slide reading device to switch the target slide 201 corresponding to the clamping port of the clamping device 30.
[0087] Specifically, after the flipping device 20 flips the slide basket 300, the clamping device 30 can remove the sample slides 200 one by one. The lifting component 23 can drive the rotating component 22, the receiving component 21 and the slide basket 300 contained in the receiving component 21 to lift and switch the position of the slide basket 300 relative to the clamping device 30. The position of the slide basket 300 relative to the clamping device 30 can also be switched by controlling the clamping device 30 to lift and switch the position of the slide basket 300 relative to the clamping device 30.
[0088] For example, the lifting assembly 23 includes a lifting drive component 231 and a lifting transmission component 232. The lifting transmission component 232 is connected to the rotating assembly 22. The lifting drive component 231 is connected to the lifting transmission component 232 and is used to drive the lifting transmission component 232 to drive the rotating assembly 22 to move vertically up and down, thereby driving the slide basket 300 to move vertically up and down. The lifting drive component 231 can be a drive motor, and the lifting transmission component 232 can be any one of a belt conveyor mechanism, chain conveyor mechanism, gear and rack transmission mechanism, or screw transmission mechanism, to drive the rotating assembly 22 to move the slide basket 300 up and down.
[0089] For example, the lifting assembly 23 also includes a guide seat 233. The guide seat 233 is equipped with a lifting guide rail 234 extending vertically. The rotating assembly 22 is slidably connected to the lifting guide rail 234. The lifting drive component 231 drives the lifting transmission component 232 to vertically lift the rotating assembly 22 along the lifting guide rail 234. By setting the lifting guide rail 234 to guide the lifting of the rotating assembly 22, the overall lifting stability of the tilting device 20 is ensured.
[0090] Please see Figure 6 , Figure 6 This is a schematic diagram of the structure of a transfer component of a film reading device provided in an embodiment of this application.
[0091] like Figure 2 and Figure 6 As shown, in some embodiments, the sample introduction device 10 includes a sample introduction track 11 and a transfer component 12, wherein the transfer component 12 is used to transfer the slide basket 300 along the sample introduction track so that the slide basket 300 is transferred from the accommodating opening to the flipping device 20.
[0092] Specifically, the sample inlet track 11 is configured to correspond to the receiving opening, and the transfer component 12 is used to transfer the slide basket 300 along the sample inlet track so that the slide basket 300 enters the receiving cavity 214 from the receiving opening. The sample inlet track 11 is provided with a preset placement position and a flip position. The slide basket 300 loaded with sample slides 200 is placed in the placement position, and the extension direction of the sample inlet track 11 is opposite to the receiving opening, and the position of the receiving cavity 214 corresponds to the flip position. The transfer component 12 is used to transfer the slide basket 300 placed in the placement position along the sample inlet track so that the slide basket 300 placed in the placement position is transferred from the receiving opening into the receiving cavity 214 and reaches the flip position.
[0093] It should be understood that when the slide reading device 100 provided in this application is used independently, samples can be manually introduced through the sample introduction track 11. Specifically, the slide basket 300 containing the sample slide 200 is placed in the placement position. When the slide reading device 100 is used in conjunction with other machines, such as when the slide reading device 100 is connected to the staining slide preparation instrument, the sample introduction track 11 can be connected to the staining slide preparation instrument, and the placement position of the sample introduction track 11 can be aligned with the sample output position of the staining slide preparation instrument, so that the staining slide preparation instrument can automatically transfer the slide basket 300 to the placement position, thereby realizing the automatic sample introduction of the slide basket 300.
[0094] In some embodiments, the transfer assembly 12 includes a transfer drive 121, a transfer transmission 122, and a pusher claw 123. The sample injection mechanism also includes a claw guide rail 13 located below and parallel to the sample injection track 11. The pusher claw 123 is slidably connected to the claw guide rail 13. The transfer drive 121 is connected to the pusher claw 123 through the transfer transmission 122. The transfer drive 121 is used to drive the transfer transmission 122 to move the pusher claw 123 along the claw guide rail 13 to push the slide basket 300 along the sample injection track 11.
[0095] For example, the transfer drive 121 can be a drive motor, and the transfer transmission 122 can be any one of a belt transmission mechanism, a chain transmission mechanism, a gear and rack transmission mechanism, or a screw transmission mechanism, so as to drive the pusher 123 to push the slide basket 300 along the sample introduction track 11.
[0096] In some embodiments, the slide basket 300 has an upper part and a lower part, the transfer assembly 12 is used to push the lower part of the slide basket 300, and the receiving assembly 21 is used to hold the upper part of the slide basket 300. Specifically, the contact position between the receiving assembly 21 and the slide basket 300 is the upper part of the slide basket 300, while the contact position between the transfer assembly 12 and the slide basket 300 is the lower part of the slide basket 300. For example, the pusher claw 123 contacts the lower part of the slide basket 300.
[0097] In other embodiments, the transfer assembly 12 is used to push the upper part of the slide basket 300, and the receiving assembly 21 is used to hold the lower part of the slide basket 300. Specifically, the receiving assembly 21 contacts the lower part of the slide basket 300, while the transfer assembly 12 contacts the upper part of the slide basket 300; for example, the pusher claw 123 contacts the upper part of the slide basket 300.
[0098] It should be understood that in the above two embodiments, when the transfer component 12 pushes the slide basket 300 into the receiving cavity 214 along the sample introduction track 11, the contact positions of the transfer component 12 and the receiving component 21 with the slide basket 300 are staggered to avoid interference between the transfer component 12 and the receiving component 21, thereby improving the transfer efficiency.
[0099] like Figure 3 As shown, in some embodiments, the controller 40 is further configured to:
[0100] After flipping the slide basket 300, the control clamping device 30 clamps the target slide 201 from the slide basket 300 and moves the target slide 201 a first distance away;
[0101] After the target slide 201 has moved a first distance, the clamping device 30 is controlled to release the clamping of the target slide 201, and the clamping device 30 is controlled to pick up the target slide 201 from the slide basket 300 and remove the target slide 201 from the slide basket 300.
[0102] Specifically, the clamping device 30 is used to clamp and move the target glass slide 201 from the slide basket 300. The controller 40 is used to control the clamping device 30 to clamp the target glass slide 201 from the slide basket 300 and move the target glass slide 201 a first distance after the sample feeding device 10 feeds the slide basket 300; after the target glass slide 201 has moved the first distance, the controller 40 controls the clamping device 30 to release the clamping of the target glass slide 201 and controls the clamping device 30 to clamp the target glass slide 201 from the slide basket 300 and move the target glass slide 201 out of the slide basket 300.
[0103] For example, when the slides in the slide basket 300 are in the second state with a side opening, the controller 40 controls the clamping device 30 to first clamp the target slide 201 from the side-opening slide basket 300 and move the target slide 201 a first distance away from the slide basket 300, so as to separate the target slide 201 from other sample slides 200, while the target slide 201 is still partially contained in the slide basket 300. After the target slide 201 has moved the first distance, the controller 40 controls the clamping device 30 to release the clamp on the target slide 201, and controls the clamping device 30 to move in the opposite direction of the displacement of the first distance and clamp the target slide 201 from the slide basket 300 for the second time, and then completely removes the target slide 201 from the slide basket 300, completing the clamping of the target slide 201.
[0104] After the clamping device 30 picks up the target slide 201 from the slide basket 300 and removes it, it transports the target slide 201 to a preset microscopic examination position on the microscopic examination device 50, allowing the microscopic examination device 50 to perform microscopic examination on the target slide 201 picked up by the clamping device 30. After the microscopic examination device 50 completes the microscopic examination of the target slide 201, the controller 40 controls the clamping device 30 to return to the position where the target slide 201 was completely removed from the slide basket 300 when it was picked up. After the clamping device 30 returns to this position, it is controlled to move in the opposite direction of the first displacement distance toward the slide basket 300, so that the target slide 201 is partially placed in the slide basket 300, at which point the target slide 201 is staggered from other sample slides 200. After the target slide 201 is partially placed in the slide basket 300, the control clamping device 30 releases its grip on the target slide 201 and moves in the opposite direction to the displacement direction of the first displacement distance to clamp the target slide 201 again. After the clamping device 30 clamps the target slide 201 again, the controller 40 controls the clamping device 30 to move in the slide basket 300 a first distance to complete the return of the target slide 201.
[0105] The clamping device 30 grips the target slide 201 and moves it a first distance out of the slide basket 300, ensuring that the target slide 201 extends at least a first distance beyond the slide basket 300, thus separating the target slide 201 from other sample slides 200. At this point, when the clamp is released and the target slide 201 is gripped again, there is no interference from non-target slides 201, and the slide can be gripped with a larger contact area, resulting in more stable gripping and transport of the target slide 201. With the slide basket 300 reduced in size and the slide spacing reduced, interference from non-target slides 201 is avoided during the gripping of the target slide 201, achieving precise gripping of the target slide 201.
[0106] Please see Figures 7 to 8 , Figure 7 This is a schematic diagram of the structure of a clamping device for a film reading device provided in an embodiment of this application. Figure 8 This is an exploded structural diagram of a clamping device for a film reading device provided in an embodiment of this application.
[0107] like Figures 3 to 8As shown, in some embodiments, the clamping device 30 includes a first clamping assembly 31 and a second clamping assembly 32 that cooperates with the first clamping assembly 31 to clamp the target glass slide 201. The first clamping assembly 31 includes a first clamping arm 311 and a first clamping member 312 connected to the first clamping arm 311 and at least partially exposed therefrom. The second clamping assembly 32 includes a second clamping arm 321 movably connected to the first clamping arm 311 and a second clamping member 322 connected to the second clamping arm 321 and at least partially exposed therefrom.
[0108] Specifically, during the process of the first clamping component 31 and the second clamping component 32 clamping the target glass slide 201, the controller 40 controls the first clamping component 312 and the second clamping component 322 to cooperate in clamping the target glass slide 201 and moving the target glass slide 201 out of the first distance, and / or controls the first clamping arm 311 and the second clamping arm 321 to cooperate in clamping the target glass slide 201 and moving the target glass slide 201 out of the slide basket 300.
[0109] For example, the first clamping member 312 and the second clamping member 322 may be elastic clamping pieces. In the displacement direction of the first displacement distance, the first clamping member 312 and the second clamping member 322 are respectively exposed on the first clamping arm 311 and the second clamping arm 321. When the controller 40 controls the clamping device 30 to clamp the target glass slide 201 for the first time, the first clamping member 312 and the second clamping member 322 cooperate to clamp the target glass slide 201. After the first clamping arm 311 and the second clamping arm 321 cooperate to perform a second clamping of the target glass slide 201 after displacement of the first distance, the target glass slide 201 is removed from the slide basket 300.
[0110] In some embodiments, the thickness of the first clamping member 312 and the second clamping member 322 in the first direction is less than the thickness of the first clamping arm 311 and the second clamping arm 321 in the first direction, where the second clamping member 322 and the first clamping member 312 move away from or closer to each other and undergo relative displacement.
[0111] By setting the thickness of the first clamping member 312 and the second clamping member 322 in the first direction to be less than the thickness of the first clamping arm 311 and the second clamping arm 321 in the first direction, when the distance between the target glass slide 201 and other sample glass slides 200 is small, the target glass slide 201 can be clamped for the first time by the first clamping member 312, which has a smaller thickness and is exposed in the first clamping arm 311, and the second clamping member 322, which is exposed in the second clamping arm 321. The target glass slide 201 is moved out of the glass slide basket 300 by a first distance, so that the target glass slide 201 extends out of the glass slide basket 300 by at least a first distance. At this time, when the target glass slide 201 is clamped again, it will not be interfered with by other sample glass slides 200. When clamping again, the glass slide can be clamped with more contact area, so as to clamp and transport the target glass slide 201 more stably in the future.
[0112] In some embodiments, the first clamping member 312 may be displaced relative to the first clamping arm 311 so that the first clamping member 312 is received in the first clamping arm 311, and / or the second clamping member 322 may be displaced relative to the second clamping arm 321 so that the second clamping member 322 is received in the second clamping arm 321.
[0113] It should be understood that, in scenarios where it is not necessary to clamp the target glass slide 201 using the first clamping member 312 and the second clamping member 322, the displacement of the first clamping member 312 relative to the first clamping arm 311 and / or the displacement of the second clamping member 322 relative to the second clamping arm 321 can be controlled so that the first clamping member 312 and the second clamping member 322 are respectively housed in the first clamping arm 311 and the second clamping arm 321, thereby achieving protection for the first clamping member 312 and the second clamping member 322 and improving the durability of the first clamping member 312 and the second clamping member 322.
[0114] For example, the displacement of the first clamping member 312 relative to the first clamping arm 311 includes, but is not limited to, the first clamping member 312 moving toward the first clamping arm 311 in the extension direction of the first clamping arm 311, and the first clamping member 312 rotating toward the first clamping arm 311 about the thickness direction of the first clamping arm 311.
[0115] Similarly, the displacement of the second clamping member 322 relative to the second clamping arm 321 includes, but is not limited to, the second clamping member 322 moving toward the second clamping arm 321 in the extension direction of the second clamping arm 321, and the second clamping member 322 rotating toward the second clamping arm 321 about the thickness direction of the second clamping arm 321.
[0116] This application also provides a slide reading method, which aims to solve the problem that the sample slide 200 is prone to sliding in or out of the slide basket 300 during the process of flipping the slide basket 300 in the existing slide reading equipment 100.
[0117] It should be noted that the film reading method can be specifically applied to the film reading device 100 provided in the above embodiments. The following will take the film reading device 100 provided in the above embodiments as an example to describe the steps of the film reading method provided in this application in detail. However, it should be understood that the film reading method is not limited to the film reading device 100 provided in the above embodiments.
[0118] Please see Figure 9 , Figure 9 This is a schematic diagram of the image reading method provided in an embodiment of this application.
[0119] like Figure 9 As shown, the image viewing method provided in this application includes steps S1-S4:
[0120] Step S1: Control the sample delivery device to transport the slide basket loaded with glass slides;
[0121] Step S2: Control the flipping device to accept the slide basket transported by the sample injection device and perform the first flipping operation on the slide basket to drive the slide basket to flip at the first speed;
[0122] Step S3: When the flipping angle of the slide basket reaches the preset first angle, control the flipping device to perform a second flipping operation on the slide basket, so as to drive the slide basket to flip to the preset angle at a second speed, wherein the second speed is less than the first speed;
[0123] Step S4: Control the clamping device to pick up the target slide from the flipped slide basket and move the target slide to the reading position to perform the corresponding reading operation.
[0124] Specifically, in combination Figures 1 to 9 The following description uses the slide reading method applied to the slide reading device 100 provided in the embodiments of this application as an example: The slide reading device 100 first controls the sample feeding device 10 to transport a slide basket 300 loaded with slides, and then controls the flipping device 20 to receive the slide basket 300 transported by the sample feeding device 10 and perform a first flipping operation on the slide basket 300 to drive the slide basket 300 to flip at a first speed. When the flipping angle of the slide basket 300 reaches a preset first angle, the flipping device 20 is controlled to perform a second flipping operation on the slide basket 300 to drive the slide basket 300 to flip at a second speed to a preset angle. The second speed is less than the first speed, so that when the slide basket 300 is flipped, it is fast at first and then slow, which does not affect the flipping speed and avoids the sample slide 200 from sliding in or out of the slide basket 300 during the flipping process, which would cause damage to the sample slide 200.
[0125] After flipping the slide basket 300 to a preset angle, the slide reading device 100 controls the clamping device 30 to clamp the target slide 201 from the flipped slide basket 300 and move the target slide 201 to the reading position to perform the corresponding reading operation.
[0126] In summary, this application provides a slide reading device 100 and a slide reading method. The slide reading device 100 includes: a sample injection device 10, a flipping device 20, a clamping device 30, and a controller 40. The sample injection device 10 is used to transport a slide basket 300 containing slides. The flipping device 20 is used to receive the slide basket 300 transported by the sample injection device 10 and flip the slide basket 300. The clamping device 30 is used to clamp a target slide 201 from the flipped slide basket 300 and transfer the target slide 201 to the reading position to perform the corresponding slide reading operation. The controller 40 is configured to... Then, the control flipping device 20 performs a first flipping operation on the slide basket 300 to drive the slide basket 300 to flip at a first speed. When the flipping angle of the slide basket 300 reaches a preset first angle, the control flipping device 20 performs a second flipping operation on the slide basket 300 to drive the slide basket 300 to flip at a second speed to a preset angle. The second speed is less than the first speed, so that when the slide basket 300 is flipped, it is fast at first and then slows down. This does not affect the flipping speed and avoids the sample slide 200 from sliding in or out of the slide basket 300 during the flipping process, which would damage the sample slide 200.
[0127] It should be understood that the modular structure diagrams shown in the accompanying drawings are merely illustrative and do not necessarily include all the connections between structures. In the description of this application, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linkage" should be interpreted broadly. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to mechanical connections or electrical connections; they can refer to direct connections or indirect connections through an intermediate medium; and they can refer to the internal communication between two components. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.
[0128] It should also be understood that the terminology used in this specification is for the purpose of describing particular embodiments only and is not intended to limit the scope of the application. As used in this specification and the appended claims, the singular forms “a,” “an,” and “the” are intended to include the plural forms unless the context clearly indicates otherwise.
[0129] It should also be understood that the term “and / or” as used in this application specification and the appended claims means any combination of one or more of the associated listed items and all possible combinations, and includes such combinations.
[0130] It should also be understood that the term "and / or" as used in this specification and the appended claims refers to any combination and all possible combinations of one or more of the associated listed items, and includes such combinations. It should be noted that, herein, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or system that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or system. Without further limitation, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or system that includes that element.
[0131] The sequence numbers of the embodiments in this application are for descriptive purposes only and do not represent the superiority or inferiority of the embodiments. The above descriptions are merely specific implementations of this application, but the scope of protection of this application is not limited thereto. Any person skilled in the art can easily conceive of various equivalent modifications or substitutions within the technical scope disclosed in this application, and these modifications or substitutions should all be covered within the scope of protection of this application. Therefore, the scope of protection of this application should be determined by the scope of the claims.
Claims
1. A reading apparatus, characterized by include: Sample delivery device, used to transport a slide basket loaded with glass slides; A flipping device for receiving the slide basket transported by the sample introduction device and flipping the slide basket; A clamping device is used to clamp a target slide from the flipped slide basket and transfer the target slide to the reading position to perform the corresponding reading operation; A controller is configured to, after the flipping device receives the slide basket, control the flipping device to perform a first flipping operation on the slide basket, so as to drive the slide basket to flip at a first speed; When the flipping angle of the slide basket reaches a preset first angle, the flipping device is controlled to perform a second flipping operation on the slide basket, so as to drive the slide basket to flip to the preset angle at a second speed, wherein the second speed is less than the first speed; The clamping device includes a first clamping assembly and a second clamping assembly that cooperates with the first clamping assembly to clamp the target glass slide. The first clamping assembly includes a first clamping arm and a first clamping member connected to the first clamping arm and at least partially exposed outside the first clamping arm. The second clamping assembly includes a second clamping arm movably connected to the first clamping arm and a second clamping member connected to the second clamping arm and at least partially exposed outside the second clamping arm. The controller controls the first clamping member and the second clamping member to cooperate in clamping the target glass slide and moving the target glass slide out of the first distance, and / or controls the first clamping arm and the second clamping arm to cooperate in clamping the target glass slide and moving the target glass slide out of the slide basket.
2. The device of claim 1, wherein, The flipping mechanism is used to flip the slide basket from a first state with an upward opening to a second state with a side opening. The slide basket transported by the sample injection device is in the first state with an upward opening, and when the slide basket is flipped to the preset angle, the slide basket is in the second state with a side opening.
3. The device of claim 1, wherein, The first angle is 30°-60°, and the preset angle is 85°-95°.
4. The device of claim 1, wherein, The flipping device is also used to drive the flipped slide basket to move up and down, so that the clamping device can switch to clamp the target slide loaded in the slide basket.
5. The device of claim 1, wherein, The flipping device includes: A receiving assembly having a receiving cavity for receiving the slide basket, and the receiving cavity having a receiving opening for the slide basket to enter and exit. A rotating assembly is used to drive the receiving assembly to rotate so as to rotate the slide basket contained in the receiving cavity.
6. The device of claim 5, wherein, The sample introduction device includes: Sample introduction track; A transfer assembly for transferring the slide basket along the sample inlet track to transfer the slide basket from the receiving opening to the flipping device.
7. The reading device according to any one of claims 1 to 6, characterized in that, The controller is also configured to: After flipping the slide basket, the clamping device is controlled to clamp the target slide from the slide basket and move the target slide a first distance away; After the target slide has moved the first distance, the clamping device is controlled to release the clamping of the target slide, and the clamping device is controlled to pick up the target slide from the slide basket and remove the target slide from the slide basket.
8. The device of claim 1, wherein, The thickness of the first clamping member and the second clamping member in the first direction is less than the thickness of the first clamping arm and the second clamping arm in the first direction. The first direction is the direction in which the second clamping member and the first clamping member move away from or towards each other and undergo relative displacement.
9. A method for viewing films, characterized in that, The method, applied to the film reading device according to any one of claims 1-8, comprises: Control the sample delivery device to transport a slide basket loaded with glass slides; The flipping device is controlled to accept the slide basket transported by the sample introduction device and perform a first flipping operation on the slide basket to drive the slide basket to flip at a first speed; When the flipping angle of the slide basket reaches a preset first angle, the flipping device is controlled to perform a second flipping operation on the slide basket, so as to drive the slide basket to flip to the preset angle at a second speed, wherein the second speed is less than the first speed; The clamping device is controlled to pick up the target slide from the flipped slide basket and move the target slide to the reading position to perform the corresponding reading operation.