Therapeutic glasses and acoustofluidic micropump for glasses

Abstract

The utility model provides an eye -glasses and acoustic fluid micro -pump for eye -glasses, acoustic fluid micro -pump (2) and medicine cavity (3) are installed to one branch leg outside the frame (4) of eye -glasses, and the medicine nozzle (1) towards the direction of the eye of the wearer is installed to one spectacle frame side of frame (4), acoustic fluid micro -pump (2) includes pump cavity (22), the medicine outlet pipe (21) and medicine inlet pipe (25) that communicate with pump cavity (22), the medicine outlet pipe (21) export end is communicated the medicine nozzle (1) through hose, the medicine outlet pipe (21) inlet end is inserted into pump cavity (22), the inner wall of pump cavity (22) is provided with the GHz level resonator (24) towards the medicine outlet pipe (21) inlet end, still be provided with the power supply part (23) of electric connection resonator (24) in pump cavity (22), the inlet end of medicine inlet pipe (25) communicates medicine cavity (3). The utility model is small in volume, light in quality, convenient to carry, and energy -conserving, and can be reused, low in cost.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of glasses, in particular to glasses for treatment and an acoustic fluid micro-pump used for glasses. BACKGROUND

[0002] The research of ocular anterior segment drug delivery system currently covers many ways such as punctal plug, subconjunctival / suprachoroidal implant, conjunctival sac implant, drug-eluting contact lenses and ocular anterior segment direct current drug iontophoresis, and the defects of the current research are that all the drug delivery methods have direct contact with the ocular surface, which can affect or change the original physiological microenvironment of the ocular surface, and the implant itself is not stable enough, the metabolic degradation period is short, long-term stable drug delivery cannot be achieved, and the post-implantation complications are also many, and the non-invasive effect cannot be completely achieved. As a new type of fluid driver, the micro-pump uses the piezoelectric / inverse piezoelectric effect to make the piezoelectric vibrator deform, and then the volume change of the pump cavity is generated to realize the output of the fluid, or the piezoelectric vibrator is used to generate fluctuation to transport the fluid.

[0003] At present, in preclinical research, the micro-pump can be used as a drug delivery system in vitro, and it is portable and wearable, but it has not been applied to ocular anterior segment drug delivery. The ocular drug delivery needs to design a portable and light micro-pump without external power supply, which is used in combination with a new way of glasses frame. In view of the above problems of the related art, there is no effective solution in the prior art. SUMMARY

[0004] Therefore, the main purpose of the present application is to provide glasses for treatment, which generates GHz acoustic fluid by an acoustic fluid micro-pump, outputs the fluid stored in the drug cavity, and continuously drops the drug solution into the eye through the drug spraying hose fixed in the center of the lens, so as to realize non-contact ocular surface precise drug delivery, safety and pollution-free, and simple operation.

[0005] To achieve the above purpose, the glasses for treatment disclosed by the present application are installed with an acoustic fluid micro-pump and a drug cavity on the outside of one leg of the glasses frame, and a drug spraying nozzle is installed on one lens frame side of the glasses frame and faces the direction of the wearer's eyes.

[0006] The acoustic fluid micro-pump comprises a pump cavity, a drug outlet pipe and a drug inlet pipe in communication with the pump cavity,

[0007] The outlet end of the drug outlet pipe is communicated with the drug spraying nozzle through a hose,

[0008] The inlet end of the drug outlet pipe extends into the pump cavity,

[0009] The inner wall of the pump cavity is provided with a GHz-level resonator facing the inlet end of the drug outlet pipe,

[0010] The pump cavity is further provided with a power supply part electrically connected to the resonator,

[0011] The inlet end of the medicine inlet pipe is communicated with the medicine cavity.

[0012] From the above, the medicine spraying nozzle, the acoustic fluid micro-pump and the medicine cavity are installed on the glasses frame, the GHz resonator is included in the acoustic fluid micro-pump, the resonator is provided with power supply through the power supply part, the continuous and stable fluid pumping can be realized, and the problems of safe and pollution-free and contactless drug delivery which cannot be guaranteed in the ocular drug delivery system are solved.

[0013] As a possible implementation manner, the inner diameter of the medicine outlet pipe increases or remains unchanged from one end close to the resonator to the other end connected to the medicine outlet pipe, and the medicine outlet pipe is arranged in non-contact with the resonator. The acoustic fluid generated by the resonator can be guided and limited.

[0014] As a possible implementation manner, the medicine outlet pipe is a hard pipe. The movement direction of the acoustic fluid can be better limited.

[0015] As a possible implementation manner, the power supply part is a wireless power supply module. The wireless power supply module can be conveniently carried and operated.

[0016] As a possible implementation manner, the medicine inlet pipe can be located at the bottom, the top or the side wall of the pump cavity. The liquid to be pumped can be introduced into the pump cavity and filled in the whole cavity without air bubbles.

[0017] As a possible implementation manner, the medicine inlet pipe is a soft pipe. The soft pipe can be more closely connected with the pump cavity to prevent liquid leakage.

[0018] An acoustic fluid micro-pump for glasses, comprising a pump cavity, a medicine outlet pipe and a medicine inlet pipe communicated with the pump cavity,

[0019] The inlet end of the medicine outlet pipe extends into the pump cavity,

[0020] The inner wall of the pump cavity is provided with a GHz-level resonator facing the inlet end of the medicine outlet pipe,

[0021] The pump cavity is further provided with a power supply part electrically connected to the resonator.

[0022] From the above, the acoustic fluid micro-pump has the advantages of simple structure, low power consumption and miniaturization, can generate strong volume force to push the liquid at the GHz-level frequency, and can obtain stable and rapid unidirectional flow through the arranged pipeline to realize continuous and rapid pumping of the fluid.

[0023] In summary, the therapeutic glasses of the present invention solve the problems of safety, pollution-free and contactless drug delivery that cannot be guaranteed in the existing anterior segment drug delivery systems. By installing the acoustofluidic micropump on the glasses frame, stable fluid output in the anterior segment of the eye can be achieved. In combination with other drug storage devices, contactless drug delivery to the eye can be achieved. The operation is simple and convenient, and the glasses are reusable and cost-saving. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 Schematic diagram of therapeutic glasses involved in a specific embodiment.

[0025] Figure 2 Schematic diagram of the acoustofluidic micropump involved in the specific implementation.

[0026] Figure 3 Schematic diagram of the medicine cavity involved in the specific implementation manner.

[0027] Explanation of the accompanying symbols: 1. spray nozzle; 2. acoustofluidic micropump; 3. medicine chamber; 4. glasses frame; 21. medicine outlet pipe; 22. pump chamber; 23. power supply unit; 24. resonator; 25. medicine inlet pipe; 31. shell; 32. inner cavity; 33. outlet. DETAILED DESCRIPTION

[0028] To make the objectives, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0029] like Figure 1 As shown, the therapeutic glasses involved in this embodiment mainly include a drug spray nozzle 1, an acoustofluidic micropump 2, a drug chamber 3 and a glasses frame 4. The drug spray nozzle 1, the acoustofluidic micropump 2 and the drug chamber 3 are connected in sequence, assembled horizontally and installed on the glasses frame 4. First, the drug solution is injected into the drug chamber 3, and the power amplifier is connected to the acoustofluidic micropump 2 to pump the drug solution. Then, the other end of the drug spray nozzle 1 connected to the acoustofluidic micropump 2 is fixed in the center of the lens and facing the wearer's eyes. The wearer can achieve vertical dripping of the drug solution into the eyes by slightly tilting his head. The material of the drug spray nozzle 1 is silicone, which has good bendability and can be cut according to different parameters. It is easy to install and simple to operate. The glasses frame 4 can be selected according to the needs of the wearer.

[0030] like Figure 2As shown, the acoustofluidic micropump 2 involved in this embodiment includes a drug outlet tube 21, a pump chamber 22, a resonator 24, a power supply unit 23, and a drug inlet tube 25. The drug outlet tube 21 is made of a glass tube. The inlet end of the drug outlet tube 21 is inserted into the pump chamber 22. The inner diameter of the pipe at the outlet end of the drug outlet tube 21 inserted into the pump chamber 22 gradually decreases, which can guide and restrict the acoustofluid. The use of a hard tube material for the drug outlet tube 21 can reduce the loss of friction resistance on the inner wall of the pipe to the fluid, and push the liquid outward more quickly. The pump chamber 22 can be used to store liquid medicine. The wireless AC power supply unit 23 is placed on the side wall of the pump chamber 22, and the GHz-level resonator 24 is placed in the direction opposite the inlet end of the drug outlet tube 21, and the drug outlet tube 21 does not contact the resonator 24. Connecting power supply 23 to resonator 24 drives resonant 24 to resonate, rapidly attenuating GHz bulk acoustic waves in the fluid. This converts acoustic energy into fluid kinetic energy, generating an acoustic fluid. This fluid is then guided and confined by boundary conditions such as the cavity and capillary tubes, achieving efficient and continuous pumping of the fluid. The drug inlet tube 25, made of a silicone hose, is positioned outside the pump chamber 22 to better seal it and prevent drug leakage. The inlet end of the drug inlet tube 25 is connected to the drug chamber 3.

[0031] like Figure 3 As shown, the medicine cavity 3 involved in this embodiment includes a shell 31, an inner cavity 32 and an outlet 33. The shell 31 is a rectangular parallelepiped structure made of polyvinyl chloride resin. The inner cavity 32 is located inside the shell 31 and is provided with an outlet 33, which can be inserted into the medicine inlet tube 25 of the acoustic fluid micropump 2 to the inner cavity 32. A portion of the inner cavity 32 is exposed to the outside of the shell 31. The exposed portion is located outside the surface of the shell 31 opposite the outlet 33. It is made of polyethylene and has a telescopic plastic bag-like structure with variable volume. By guiding and restricting the fluid through boundary conditions such as the cavity and capillary, energy loss can be prevented and fluid transport can be achieved. The dimensions of the inner cavity 32 and the shell 31 can be selected in different specifications according to the wearer's demand for medicine dosage, such as 300ul, 500ul and 1000ul. The medicine cavity 3 can be made of the shell 31 and the inner cavity 32 using 3D printing technology, and then firmly glued with shadowless adhesive. The medicine chamber 3 is removable and replaceable, making it easy and cost-effective to operate. It can be sterilized and reused repeatedly, or it can be discarded as a disposable medical device. Made of food-grade materials, it can be safely applied to the human body without contamination. The medicine chamber 3 can be used in conjunction with the acoustofluidic micropump 2 and mounted on an eyeglass frame 4 for use by the wearer.

[0032] When using the therapeutic eyewear described in this embodiment, the drug inlet tube 25 of the acoustofluidic micropump 2 is inserted into the outlet 33 of the drug chamber 3, ensuring a tight connection to prevent leakage. The drug spray nozzle 1 is then tightly connected to the drug outlet tube 21 of the acoustofluidic micropump 2. The other end of the drug spray nozzle 1 is fixed to the center of the lens. The assembled drug spray device is mounted on the eyeglass frame 4. The wearer can then slightly tilt their head to drip the drug solution into the eye. First, by pressing the exposed portion of the inner cavity 32 to create an air pressure differential, atmospheric pressure is used to push the liquid in the drug chamber 3 into the acoustofluidic micropump 2. This operation is simple and convenient, and does not contaminate the drug solution. After the drug solution enters the acoustofluidic micropump 2 through the drug inlet tube 25, the GHz-frequency AC power supply 23 within the pump chamber 22 drives the resonator 24 to resonate, generating a GHz acoustic fluid, which is then guided and confined by the drug outlet tube 21. One end of the spray nozzle 1 is connected to the drug outlet tube 21, and the other end is fixed to the center of the lens facing the wearer's eye. The drug solution passes through the drug outlet tube 21 and enters the spray nozzle 1, causing the drug solution to drip into the wearer's eye. The efficiency of fluid delivery is related to the density of the drug solution and the boundary conditions such as the cavity and capillary. By continuously applying pressure to the drug cavity 3, the acoustofluidic micropump 2 can continuously pump fluid, continuously dripping the drug solution into the wearer's eye.

[0033] In summary, the therapeutic glasses involved in this embodiment mainly include a glasses frame equipped with an acoustofluidic micropump, a drug spray nozzle 1 and a drug chamber 3. The drug spray nozzle 1, the acoustofluidic micropump 2 and the drug chamber 3 are connected in sequence and installed on the glasses frame 4, which can realize contactless medication for the eyes. The operation is simple and convenient, safe and pollution-free, easy to carry and low cost, and has great potential and prospects in the research and development and clinical application of ophthalmic drug delivery systems.

[0034] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

[0035] For example, in the above embodiment, the exposed portion is located on the exterior of the surface of the housing 31 directly opposite the outlet 33. However, it can also be located on the exterior of a surface of the housing 31 away from the frame, or on a surface without the outlet 33. The exposed portion can be single or multiple, such as one exposed portion on each of two parallel surfaces without the outlet 33, which can be pressed simultaneously to promote the discharge of the drug solution. Furthermore, the inner diameter of the outlet end of the drug outlet tube 21 can be gradually reduced or kept constant, both of which can guide and restrict the acoustic fluid flow.

[0036] In addition, in the above embodiment, some parameter ranges of a pair of therapeutic glasses are described. However, these parameters do not constitute a limitation to the present invention, and the present invention may also adopt other parameters.

Claims

1. A pair of glasses for treatment, characterized in that: An acoustic fluid micro pump (2) and a medicine chamber (3) are installed on the outside of one leg of a glasses frame (4), and a medicine spray nozzle (1) facing the wearer's eyes is installed on a lens frame side of the glasses frame (4); The acoustofluidic micropump (2) comprises a pump chamber (22), a drug outlet pipe (21) and a drug inlet pipe (25) connected to the pump chamber (22). The outlet end of the medicine outlet pipe (21) is connected to the medicine spray nozzle (1) through a hose. The inlet end of the medicine outlet pipe (21) extends into the pump cavity (22). The inner wall of the pump chamber (22) is provided with a GHz-level resonator (24) facing the inlet end of the medicine outlet pipe (21), which generates GHz body sound waves that decay rapidly in the fluid, converting sound energy into fluid kinetic energy, thereby generating an acoustic fluid that enters the medicine outlet pipe (21); A power supply unit (23) electrically connected to the resonator (24) is also provided in the pump cavity (22). The inlet end of the medicine inlet pipe (25) is connected to the medicine cavity (3).

2. The therapeutic glasses according to claim 1, characterized in that The inner diameter of the medicine outlet tube (21) generally increases or remains unchanged from its inlet end to its outlet end. Furthermore, the medicine outlet pipe (21) and the resonator (24) are arranged in a non-contact manner.

3. The therapeutic glasses according to claim 2, characterized in that: The medicine outlet pipe (21) is a hard pipe.

4. The therapeutic glasses according to claim 1, characterized in that The power supply unit (23) is a wireless power supply module.

5. The therapeutic glasses according to claim 1, characterized in that: The drug inlet pipe (25) may be located at the bottom, top or side wall of the pump chamber (22).

6. The therapeutic glasses according to claim 1, characterized in that: The medicine inlet pipe (25) is a flexible pipe.

7. An acoustofluidic micropump for glasses, characterized in that: It comprises a pump chamber (22), a medicine outlet pipe (21) and a medicine inlet pipe (25) connected to the pump chamber (22). The inlet end of the medicine outlet pipe (21) extends into the pump cavity (22). The inner wall of the pump chamber (22) is provided with a GHz-level resonator (24) facing the inlet end of the medicine outlet pipe (21), which generates GHz body sound waves that decay rapidly in the fluid, converting sound energy into fluid kinetic energy, thereby generating an acoustic fluid that enters the medicine outlet pipe (21); A power supply portion (23) electrically connected to the resonator (24) is also provided in the pump cavity (22).

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