Multi-mode imaging uterine endoscope and method integrating optics, photoacoustics and ultrasound

Abstract

The multi-mode imaging uterine endoscope and method integrated with optics, photoacoustics and ultrasound disclosed in the present disclosure include an external hollow sleeve, an ultrasonic transducer, a reflector and an internal sleeve are sequentially arranged in the external hollow sleeve, an imaging window is also arranged on the external hollow sleeve, the imaging window is located at a position corresponding to the position of the ultrasonic transducer and the reflector, the front end of the internal sleeve is located in the external hollow sleeve, the rear end of the internal sleeve extends out of the external hollow sleeve, an optical fiber and an imaging channel are arranged in the internal sleeve, one end of the optical fiber is used to connect with a laser generator and a cold light source, and the other end is connected with a fiber coupler, a self-focusing lens is arranged at the front end of the fiber coupler, the self-focusing lens and one end of the imaging channel are both located at the front end of the internal sleeve, an imaging objective lens is arranged on the imaging channel, and the imaging objective lens is connected to an image acquisition device. The endometrium is imaged by three modes of optics, photoacoustics and ultrasound, so as to realize a comprehensive observation of the endometrium.

Description

Technical Field

[0001] The present invention relates to the technical field of endoscopes, and in particular to a multi-mode imaging uterine endoscope and method integrating optics, photoacoustics and ultrasound. Background Art

[0002] The statements in this section merely provide background information related to the present disclosure and do not necessarily constitute prior art.

[0003] At present, non-invasive observation of the endometrium is mainly carried out through magnetic resonance imaging and ultrasound observation. Although magnetic resonance imaging can evaluate characteristic information such as endometrial myometrium and cervical infiltration, and can have good tissue contrast, the spatial resolution and temporal resolution of magnetic resonance imaging equipment are limited. At the same time, the resonance imaging equipment is relatively large and is limited by the venue, making it inconvenient to use; ultrasound observation is based on the acoustic impedance characteristics of different tissues to image the tissue of the endometrium, but the spatial resolution of the imaging is poor, the tissue contrast is also limited, and the surface image of the endometrium cannot be obtained. Therefore, the current non-invasive observation of the endometrium cannot achieve convenient and comprehensive observation of the endometrium. Summary of the invention

[0004] In order to solve the above problems, the present disclosure proposes a multi-mode imaging uterine endoscope and method integrating optics, photoacoustics and ultrasound, which can image the endometrium through three modes of optics, photoacoustics and ultrasound, thereby realizing comprehensive observation of the endometrium.

[0005] To achieve the above objectives, the present disclosure adopts the following technical solutions:

[0006] On the first aspect, a multi-mode imaging uterine endoscope integrating optics, photoacoustics and ultrasound is proposed, including an external hollow sleeve, in which an ultrasonic transducer, a reflector and an internal sleeve are arranged in sequence, and an imaging window is also arranged on the external hollow sleeve, and the imaging window is located at a position corresponding to the positions of the ultrasonic transducer and the reflector, the front end of the internal sleeve is located in the external hollow sleeve, and the rear end of the internal sleeve extends out of the external hollow sleeve, an optical fiber and an imaging channel are arranged in the internal sleeve, one end of the optical fiber is used to connect to a laser generator and a cold light source, and the other end is connected to a fiber coupler, a self-focusing lens is arranged at the front end of the fiber coupler, the self-focusing lens and one end of the imaging channel are both located at the front end of the internal sleeve, an imaging objective lens is arranged on the imaging channel, and the imaging objective lens is connected to an image acquisition device.

[0007] Secondly, a multi-modal imaging method integrating optics, photoacoustics and ultrasound is proposed, including:

[0008] When the laser generator emits laser, the laser is transmitted to the fiber coupler through the optical fiber for coupling. After coupling, the light is focused by the self-focusing lens and projected to the reflector. The reflector reflects the light. After reflection, the light passes through the imaging window and enters the surface of the endometrium, stimulating a photoacoustic signal. The photoacoustic signal is detected by the ultrasonic transducer to obtain a photoacoustic image of the endometrium.

[0009] When the ultrasonic transducer emits an ultrasonic signal, the ultrasonic signal is transmitted to the surface of the endometrium, and the ultrasonic signal reflected by the endometrium is detected by the ultrasonic transducer to obtain an endometrial ultrasonic image;

[0010] When the cold light source emits cold light, the cold light is transmitted to the optical fiber coupler through the optical fiber for coupling. After coupling, the light is focused by the self-focusing lens and projected to the reflector. The reflector reflects the light. After reflection, the light passes through the imaging window and enters the surface of the endometrium. The image acquisition device obtains an optical image of the endometrium surface through the imaging device.

[0011] Comprehensive analysis of the endometrium is performed using photoacoustic images, ultrasound images, and optical images.

[0012] Compared with the prior art, the present invention has the following beneficial effects:

[0013] 1. The present invention can image the endometrium through optical, photoacoustic and ultrasonic modes, combining the unique advantages of the three imaging modes. It can not only use optical imaging to obtain the surface structure imaging of the endometrium, but also use ultrasonic and photoacoustic imaging to obtain internal information. Therefore, it can obtain a physical image of the endometrium with multi-parameter information and multi-structural characteristics, realizing a comprehensive observation of the endometrium.

[0014] 2. The image acquisition device of the present invention acquires images of the endometrium and the ultrasonic transducer acquires photoacoustic images of the endometrium through the imaging window, so as to observe and image the same position of the endometrium, thereby ensuring the accuracy of comprehensive detection of the same position of the endometrium.

[0015] Advantages of additional aspects of the present invention will be given in part in the following description, and in part will become obvious from the following description, or will be learned through practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] The drawings in the specification, which constitute a part of the present application, are used to provide further understanding of the present application. The illustrative embodiments of the present application and their descriptions are used to explain the present application and do not constitute improper limitations on the present application.

[0017] Figure 1 This is a simplified diagram of the structure of the uterine endoscope disclosed in Example 1.

[0018] Wherein: 1. protective cover, 2. outer shell, 3. outer hollow sleeve, 4. inner sleeve, 5. sealed water tank, 6. ultrasonic transducer, 7. reflector, 8. imaging window, 9. multimode optical fiber, 10. optical fiber coupler, 11. self-focusing lens, 12. imaging channel, 13. motor, 14. image acquisition device, 15. transmission component, 16. bearing, 17. fixing component, 18. fixing component, 19. ultrasonic high-frequency data line, 20. motor control line, 21. image acquisition device data line.

[0019] Figure 2 This is a cross-sectional view of the internal sleeve disclosed in Example 1. DETAILED DESCRIPTION

[0020] The present disclosure is further described below in conjunction with the accompanying drawings and embodiments.

[0021] It should be noted that the following detailed descriptions are illustrative and are intended to provide further explanation of the present application. Unless otherwise specified, all technical and scientific terms used herein have the same meanings as those commonly understood by those skilled in the art to which the present application belongs.

[0022] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, it indicates the presence of features, steps, operations, devices, components and / or combinations thereof.

[0023] In the present disclosure, terms such as "upper", "lower", "left", "right", "front", "back", "vertical", "horizontal", "side", "bottom" and the like indicating directions or positional relationships are based on the directions or positional relationships shown in the accompanying drawings. They are relational words determined only for the convenience of describing the structural relationships of the various parts or elements of the present disclosure, and do not specifically refer to any part or element in the present disclosure and should not be understood as limitations on the present disclosure.

[0024] In the present disclosure, terms such as "fixed connection", "connected", "connection", etc. should be understood in a broad sense, indicating that it can be fixedly connected, integrally connected or detachably connected; it can be directly connected or indirectly connected through an intermediate medium. For relevant scientific research or technical personnel in this field, the specific meanings of the above terms in the present disclosure can be determined according to specific circumstances, and they cannot be understood as limitations on the present disclosure.

[0025] Example 1

[0026] In this embodiment, a multi-mode imaging uterine endoscope integrating optics, photoacoustics and ultrasound is disclosed, including an external hollow sleeve, in which an ultrasonic transducer, a reflector and an internal sleeve are sequentially arranged, an imaging window is also arranged on the external hollow sleeve, and the imaging window is located at a position corresponding to the positions of the ultrasonic transducer and the reflector, the front end of the internal sleeve is located in the external hollow sleeve, and the rear end of the internal sleeve extends out of the external hollow sleeve, an optical fiber and an imaging channel are arranged in the internal sleeve, one end of the optical fiber is used to be connected to a laser generator and a cold light source, and the other end is connected to a fiber coupler, a self-focusing lens is arranged at the front end of the fiber coupler, the self-focusing lens and one end of the imaging channel are both located at the front end of the internal sleeve, an imaging objective lens is arranged on the imaging channel, and the imaging objective lens is connected to an image acquisition device.

[0027] Furthermore, the optical fiber adopts a multimode optical fiber.

[0028] Furthermore, the imaging window is a ring-shaped transparent window.

[0029] Furthermore, a shell is arranged outside the outer hollow sleeve.

[0030] Furthermore, a protective cover is provided on the outside of the shell.

[0031] Furthermore, a motor is arranged on the inner sleeve, and an output shaft of the motor is connected to the outer hollow sleeve through a transmission assembly, and when the output shaft of the motor rotates, the outer hollow sleeve can be driven to rotate.

[0032] Furthermore, the transmission assembly is a gear transmission, a belt transmission or a chain transmission.

[0033] Furthermore, a handheld component is sleeved on the rear end of the internal sleeve, and the motor, transmission assembly and image acquisition device are all located inside the handheld component.

[0034] Furthermore, the outer hollow sleeve is connected to the inner sleeve via a bearing.

[0035] The multi-mode imaging hysteroscope disclosed in this embodiment, which integrates optics, photoacoustics and ultrasound, is described in detail.

[0036] In order to achieve comprehensive observation of the endometrium, the multi-mode imaging hysteroscope integrating optics, photoacoustics and ultrasound disclosed in this embodiment integrates three imaging modes: optics, photoacoustics and ultrasound.

[0037] Among them, photoacoustic observation is a non-destructive biophoton imaging method based on the difference in optical absorption inside biological tissues and using ultrasound as a medium. It combines the advantages of high contrast characteristics of pure optical imaging and high penetration depth characteristics of pure ultrasound imaging. When the laser irradiates biological tissues, local thermal expansion will occur, thereby generating sound waves. The information detected by ultrasound is transmitted to a computer, and the tissue image is reconstructed based on the light absorption of different tissues, thereby reflecting the physiological information inside the tissue. Photoacoustic observation can reflect the parameter information of tissue optical absorption differences.

[0038] like Figure 1 , Figure 2 As shown, the multi-mode imaging uterine endoscope integrating optics, photoacoustics and ultrasound disclosed in this embodiment includes: an external hollow sleeve 3, an internal sleeve 4, an optical transmission path, an optical imaging component, an imaging window 8, a reflector 7, an image acquisition device 14 and an ultrasonic transducer 6.

[0039] The ultrasonic transducer 6 , the reflector 7 and the inner sleeve 4 are coaxially arranged in the outer hollow sleeve 3 in sequence. The front end of the inner sleeve 4 is located in the outer hollow sleeve 3 , and the rear end extends out from the outer hollow sleeve 3 .

[0040] The ultrasonic transducer is a water-immersed piezoelectric transducer, which is used for the excitation of ultrasonic signals and the detection of photoacoustic signals and ultrasonic signals to form photoacoustic images and ultrasonic images.

[0041] In order to reduce noise and other interference, a sealed water tank 5 is provided on the ultrasonic transducer 6, and an ultrasonic coupling medium is placed in the sealed water tank 5. The ultrasonic coupling medium can be deionized water.

[0042] The reflector adopts a flat metal reflector to meet the needs of different imaging methods.

[0043] An imaging window 8 is also provided on the external hollow sleeve 3, and the imaging window 8 is located at a position corresponding to the position of the ultrasonic transducer 6 and the reflector 7, so that the light reflected by the reflector 7 can pass through the imaging window 8 and illuminate the endometrium, and the photoacoustic signal generated after the endometrium is excited can also be received by the ultrasonic transducer 6 through the imaging window 8.

[0044] The optical transmission path includes an optical fiber 9 , a fiber coupler 10 and a self-focusing lens 11 .

[0045] The optical imaging assembly includes an imaging channel 12 and an imaging objective lens.

[0046] The inner sleeve 4 is a cylindrical structure, and an optical fiber channel and an imaging channel 12 are opened on the inner sleeve 4 along the axial direction of the inner sleeve 4 .

[0047] The size of the optical fiber channel is adapted to that of the optical fiber 9, which is located in the optical fiber channel. One end of the optical fiber 9 is used to connect to a laser generator and a cold light source, and the other end is connected to an optical fiber coupler 10. A self-focusing lens 11 is provided at the front end of the optical fiber coupler 10, and the self-focusing lens 11 is provided at the front end of the internal sleeve 4. The light emitted by the laser generator or the cold light source can enter the optical fiber coupler 10 through the optical fiber 9 for coupling, and the coupled light is focused by the self-focusing lens 11 and then enters the reflector 7 for reflection.

[0048] An imaging objective lens is arranged on the imaging channel 12 . The imaging objective lens is a white light imaging objective lens. The imaging objective lens collects the endometrial surface image through the imaging channel 12 .

[0049] The image acquisition device 14 is passed through the internal sleeve 4 and connected to the imaging objective lens, and an optical image of the endometrial surface is acquired through the image acquisition device 14 .

[0050] In the specific implementation, the laser generator used is a pulse laser, the wavelength range of the pulse laser emitted is 400nm~2600nm, the wavelength range covers the visible light band and the near infrared band, the pulse width is 5ns~50ns, and the types of pulse lasers include semiconductor lasers, solid lasers, dye lasers or gas lasers. This embodiment uses the OPO laser of EKSPKLA company, the output wavelength range is 400nm~2600nm, the pulse repetition frequency is 1KHz, and the pulse width is less than 10ns.

[0051] The outer hollow sleeve has an outer diameter of 9 mm and an inner diameter of 8 mm, and the inner sleeve has an outer diameter of 6 mm.

[0052] The imaging window is a transparent annular piece that allows the transmission of optical and acoustic waves.

[0053] The ultrasonic transducer uses a water-immersed ultrasonic transducer with a center frequency of 40 MHz, a bandwidth of 60%, and a size of 0.6 mm*0.5 mm*0.2 mm. The water-immersed piezoelectric transducer can achieve high-resolution imaging.

[0054] The optical fiber 9 is a multimode optical fiber, which is made of plastic, quartz or multi-component glass fiber, and preferably has a core of 50 μm and a cladding of 125 μm.

[0055] The imaging objective lens is a white imaging objective lens.

[0056] The image acquisition device uses a micro-focus optical camera with a diameter of 3.5mm and a pixel of 1280*720.

[0057] In order to achieve 360° annular scanning imaging of endometrial tissue, a motor 13 and a transmission assembly 15 are also provided. The motor 13 is a hollow motor fixed on the internal sleeve 4. The output shaft of the motor 13 is connected to the external hollow sleeve 3 via the transmission assembly 15. When the output shaft of the motor 13 rotates, the external hollow sleeve 3 is driven to rotate through the transmission assembly 15.

[0058] The ultrasonic transducer 6 and the reflector 7 are both mechanically connected to the external hollow sleeve 3. When the external hollow sleeve 3 rotates, the ultrasonic transducer 6 and the reflector 7 are driven to rotate together, thereby achieving 360° annular scanning imaging of the endometrium.

[0059] Motor 13 is a micro stepping motor.

[0060] The transmission component 15 can be a gear drive, a belt drive or a chain drive. Taking the gear drive as an example, the transmission component 15 includes an internal gear and an external gear. The internal gear is meshed with the external gear. The internal gear is fixed on the output shaft of the motor 13 and can rotate with the output shaft. The external hollow sleeve 3 is fixed on the external gear. The internal gear drives the external gear to rotate, thereby driving the external hollow sleeve 3 to rotate.

[0061] In order to ensure the stability of the rotation of the outer hollow sleeve 3 , a bearing 16 is provided at the connection between the outer hollow sleeve 3 and the inner sleeve 4 .

[0062] An outer hollow sleeve 3 is placed inside the housing 2 as the probe portion of the hysteroendoscope disclosed in this embodiment.

[0063] The shell 2 is a transparent hard shell made of acrylic material to achieve packaging for the entire probe part, with an outer diameter of 12 mm, an inner diameter of 10 mm, and a length of 10 cm.

[0064] The rear end of the internal sleeve 4 , the motor 13 , the transmission assembly and the image acquisition device are all placed in the handheld component, and the handheld component is connected to the housing 2 .

[0065] The motor 13 is connected to the handheld component via a fixing assembly 17 , and the inner sleeve 4 is connected to the handheld component via a fixing assembly 18 .

[0066] The fixing assembly 17 and the fixing assembly 18 both include a fixing block, and the fixing block is connected to the motor, the internal sleeve or the handheld component through bolts.

[0067] The optical fiber 9, the ultrasonic high-frequency data line 19 connected to the ultrasonic transducer 6, the motor control line 20 connected to the motor 13, and the image acquisition device data line 21 connected to the image acquisition device are all led out from the handheld component.

[0068] In order to avoid direct contact between the endoscope and the endometrial tissue and to improve the reuse rate of the endoscope in a short time, a replaceable protective cover 1 is provided on the outside of the housing 2, and the protective cover 1 is connected to the handheld component.

[0069] The protective cover 1 is made of medical-grade light-transmitting and sound-transmitting material. The protective cover 1 is sealed at the top of the probe, and is designed to be open at the contact with the handheld component. It is connected and fixed to the handheld component through an interface, and the interface is a Luer interface.

[0070] The motor, ultrasonic transducer, image acquisition device, laser generator, and cold light source are all connected to the control system. The control system receives the photoacoustic image and ultrasonic image acquired by the ultrasonic transducer, and the optical image acquired by the image acquisition device, and controls the start and stop of the motor, ultrasonic transducer, laser generator, and cold light source.

[0071] The multi-mode imaging uterine endoscope disclosed in this embodiment integrates optics, photoacoustics and ultrasound. The specific imaging process is as follows: a laser generator emits a laser, which is transmitted to a fiber coupler through an optical fiber for coupling. After coupling, the light is focused by a self-focusing lens and then projected to a reflector. The reflector reflects the light. After reflection, the light passes through an imaging window and enters the surface of the endometrium, stimulating a photoacoustic signal. The photoacoustic signal is detected by an ultrasonic transducer to obtain a photoacoustic image of the endometrium.

[0072] After the laser generator outputs the laser, the ultrasonic transducer emits an ultrasonic signal after a certain delay to avoid the aliasing of the ultrasonic signal and the photoacoustic signal. The ultrasonic signal is transmitted to the surface of the endometrium, and the ultrasonic signal reflected by the endometrium is detected by the ultrasonic transducer to obtain an endometrial ultrasonic image.

[0073] A cold light source emits cold light, which is transmitted to a fiber coupler through an optical fiber for coupling. After coupling, the light is focused by a self-focusing lens and then projected to a reflector. The reflector reflects the light, and after reflection, the light passes through an imaging window and enters the surface of the endometrium. An image acquisition device obtains an optical image of the surface of the endometrium through an imaging device.

[0074] Comprehensive analysis of the endometrium through photoacoustic, ultrasound, and optical images;

[0075] After collecting the photoacoustic image, ultrasound image and optical image of a certain part of the endometrium, the micro-stepping motor is controlled to drive the reflector located in the external hollow sleeve to rotate, and the photoacoustic image, ultrasound image and optical image of the next endometrial tissue are collected, thereby completing the 360° annular data collection of the endometrium.

[0076] The multi-mode imaging hysteroendoscope that integrates optics, photoacoustics, and ultrasound disclosed in this embodiment can image the endometrium through the three modes of optics, photoacoustics, and ultrasound, and combines the unique advantages of the three imaging modes. It can not only use optical imaging to obtain the surface structure imaging of the endometrium, but also use ultrasound and photoacoustic imaging to obtain internal information, so that the physical image of the endometrium with multi-parameter information and multi-structural features can be obtained, realizing a comprehensive observation of the endometrium. The image acquisition device acquires the image of the endometrium and the ultrasonic transducer acquires the photoacoustic image of the endometrium through the imaging window, which is for the observation imaging of the same position of the endometrium, ensuring the accuracy of the comprehensive detection of the same position of the endometrium.

[0077] Example 2

[0078] In this embodiment, a multi-mode imaging method integrating optics, photoacoustics and ultrasound is disclosed, including:

[0079] When the laser generator emits laser, the laser is transmitted to the fiber coupler through the optical fiber for coupling. After coupling, the light is focused by the self-focusing lens and projected to the reflector. The reflector reflects the light. After reflection, the light passes through the imaging window and enters the surface of the endometrium, stimulating a photoacoustic signal. The photoacoustic signal is detected by the ultrasonic transducer to obtain a photoacoustic image of the endometrium.

[0080] When the ultrasonic transducer emits an ultrasonic signal, the ultrasonic signal is transmitted to the surface of the endometrium, and the ultrasonic signal reflected by the endometrium is detected by the ultrasonic transducer to obtain an endometrial ultrasonic image;

[0081] When the cold light source emits cold light, the cold light is transmitted to the optical fiber coupler through the optical fiber for coupling. After coupling, the light is focused by the self-focusing lens and projected to the reflector. The reflector reflects the light. After reflection, the light passes through the imaging window and enters the surface of the endometrium. The image acquisition device obtains an optical image of the endometrium surface through the imaging device.

[0082] Comprehensive analysis of the endometrium is performed using photoacoustic images, ultrasound images, and optical images.

[0083] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the above embodiments, ordinary technicians in the relevant field should understand that the specific implementation methods of the present invention can still be modified or replaced by equivalents. Any modification or equivalent replacement that does not depart from the spirit and scope of the present invention should be covered within the scope of protection of the claims of the present invention.

Claims

1. A multi-mode imaging hysteroscope integrating optics, photoacoustics and ultrasound, characterized in that: The device comprises an external hollow sleeve, wherein an ultrasonic transducer, a reflector and an internal sleeve are sequentially arranged in the external hollow sleeve, an imaging window is also arranged on the external hollow sleeve, and the imaging window is located at a position corresponding to the positions of the ultrasonic transducer and the reflector, the front end of the internal sleeve is located in the external hollow sleeve, and the rear end of the internal sleeve extends out of the external hollow sleeve, an optical fiber and an imaging channel are arranged in the internal sleeve, one end of the optical fiber is used to connect with a laser generator and a cold light source, and the other end is connected with an optical fiber coupler, a self-focusing lens is arranged at the front end of the optical fiber coupler, and the self-focusing lens and one end of the imaging channel are both located at the front end of the internal sleeve, an imaging objective lens is arranged on the imaging channel, and the imaging objective lens is connected with an image acquisition device; A motor is arranged on the inner sleeve, and the output shaft of the motor is connected to the outer hollow sleeve through a transmission assembly, and when the output shaft of the motor rotates, the outer hollow sleeve can be driven to rotate; The ultrasonic transducer and the reflector are mechanically connected to the external hollow sleeve. When the external hollow sleeve rotates, the ultrasonic transducer and the reflector are driven to rotate together, thereby achieving 360° annular scanning imaging of the endometrium.

2. The multi-mode imaging hysteroendoscope integrating optics, photoacoustics and ultrasound as claimed in claim 1, characterized in that: The optical fiber adopts multimode optical fiber.

3. The multi-mode imaging hysteroendoscope integrating optics, photoacoustics and ultrasound as claimed in claim 1, characterized in that: The imaging window adopts an annular transparent window.

4. The multi-mode imaging hysteroendoscope integrating optics, photoacoustics and ultrasound as claimed in claim 1, characterized in that: The outer casing of the outer hollow casing is provided.

5. The multi-mode imaging hysteroendoscope integrating optics, photoacoustics and ultrasound as claimed in claim 4, characterized in that: A protective cover is arranged on the outside of the shell.

6. The multi-mode imaging hysteroendoscope integrating optics, photoacoustics and ultrasound as claimed in claim 1, characterized in that: The transmission assembly is gear transmission, belt transmission or chain transmission.

7. The multi-mode imaging hysteroendoscope integrating optics, photoacoustics and ultrasound as claimed in claim 1, characterized in that: A handheld component is sleeved on the rear end of the internal sleeve, and the motor, the transmission component and the image acquisition device are all located in the handheld component.

8. The multi-mode imaging hysteroendoscope integrating optics, photoacoustics and ultrasound as claimed in claim 1, characterized in that: The outer hollow sleeve is connected to the inner sleeve through a bearing.

9. A multi-mode imaging method integrating optics, photoacoustics and ultrasound, applied to a multi-mode imaging hysteroscope integrating optics, photoacoustics and ultrasound as claimed in claim 1, characterized in that: include: When the laser generator emits laser, the laser is transmitted to the fiber coupler through the optical fiber for coupling. After coupling, the light is focused by the self-focusing lens and projected to the reflector. The reflector reflects the light. After reflection, the light passes through the imaging window and enters the surface of the endometrium, stimulating a photoacoustic signal. The photoacoustic signal is detected by the ultrasonic transducer to obtain a photoacoustic image of the endometrium. When the ultrasonic transducer emits an ultrasonic signal, the ultrasonic signal is transmitted to the surface of the endometrium, and the ultrasonic signal reflected by the endometrium is detected by the ultrasonic transducer to obtain an endometrial ultrasonic image; When the cold light source emits cold light, the cold light is transmitted to the optical fiber coupler through the optical fiber for coupling. After coupling, the light is focused by the self-focusing lens and projected to the reflector. The reflector reflects the light. After reflection, the light passes through the imaging window and enters the surface of the endometrium. The image acquisition device obtains an optical image of the endometrium surface through the imaging device. Comprehensive analysis of the endometrium is performed using photoacoustic images, ultrasound images, and optical images.

Images