Left atrial appendage occlusion ablation device and system

Abstract

The embodiment of the application provides a left atrial appendage occlusion and ablation device and a system thereof, and relates to the technical field of interventional medical instruments.The left atrial appendage occlusion and ablation device comprises an anchoring disc, a sealing disc and an insulating connecting piece.A first conductive part is arranged on the anchoring disc, and a second conductive part is arranged on the sealing disc, and the first conductive part and the second conductive part are used for transmitting ablation energy to tissue.The left atrial appendage occlusion and ablation device combines ablation and occlusion, simplifies the procedure of a one-stop treatment operation of 'ablation+left atrial appendage occlusion', and helps to reduce the operation difficulty.The two ends of the insulating connecting piece are connected with the anchoring disc and the sealing disc respectively, so that the first conductive part and the second conductive part are electrically isolated through the insulating connecting piece, the insulating effect is good, and the ablation success rate is improved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of interventional medical devices, in particular to a left atrial appendage occlusion and ablation device and a system thereof. BACKGROUND

[0002] Atrial fibrillation (AF) is the most common sustained arrhythmia, and its incidence increases with age, reaching 10% in people over 75 years old. The prevalence of AF is also closely related to diseases such as coronary heart disease, hypertension, and heart failure. The left atrial appendage (LAA) is not only the main site of thrombus formation in AF, but also one of the key areas for the occurrence and maintenance of AF. Some AF patients can benefit from active LAA electrical isolation.

[0003] A one-stop treatment method combining catheter radiofrequency ablation and LAA occlusion has achieved many successful cases of treating AF. Currently, a one-stop treatment method combining catheter radiofrequency ablation and LAA occlusion has achieved many successful cases of treating AF. In the one-stop treatment method, through LAA occlusion, patients can still obtain good stroke prevention effect without the need for lifelong anticoagulant drugs; combined with catheter radiofrequency ablation to restore and maintain sinus rhythm and improve the symptoms of AF patients, patients can obtain stable long-term treatment effect. However, in order to perform ablation and occlusion of the LAA during the above one-stop treatment, it is necessary to introduce an ablation catheter and a LAA occlusion and ablation device in an interventional manner, and the key is to position the two devices at the LAA ostium position in sequence, and then perform ablation and occlusion, respectively. Since the ablation catheter and the LAA occlusion are difficult to position at the LAA ostium, the surgical procedure is complex and time-consuming, which is not conducive to improving the convenience of the "ablation + LAA occlusion" one-stop treatment surgery. SUMMARY

[0004] The purposes of the present application include, for example, providing a left atrial appendage occlusion and ablation device that can effectively improve the technical problems of complex and difficult "ablation + LAA occlusion" one-stop treatment surgery procedures in the prior art.

[0005] The purposes of the present application also include providing a left atrial appendage occlusion and ablation system that can effectively improve the technical problems of complex and difficult "ablation + LAA occlusion" one-stop treatment surgery procedures in the prior art.

[0006] Embodiments of the present application can be implemented as follows:

[0007] The left auricle occlusion ablation device provided by the embodiment of the present application comprises an anchoring disc, a sealing disc and an insulating connecting piece.

[0008] The embodiment of the present application also provides a left auricle occlusion ablation system.

[0009] The left auricle occlusion ablation device and the system thereof have the following beneficial effects, for example:

[0010] The left auricle occlusion ablation device provided by the embodiment of the present application comprises an anchoring disc, a sealing disc and an insulating connecting piece. The anchoring disc is provided with a first conductive part, and the sealing disc is provided with a second conductive part. The first conductive part and the second conductive part are used for transmitting ablation energy to tissues. The two ends of the insulating connecting piece are connected with the anchoring disc and the sealing disc respectively, so that the first conductive part and the second conductive part are electrically isolated through the insulating connecting piece. The left auricle occlusion ablation device combines ablation and occlusion, simplifies the procedure of one-stop treatment surgery of 'ablation+left auricle occlusion', and helps to reduce the difficulty of surgery. Meanwhile, the anchoring disc and the sealing disc are connected through the insulating connecting piece, the insulation performance between the first conductive part and the second conductive part is improved, and the success rate of ablation is improved.

[0011] The embodiment of the present application also provides a left auricle occlusion ablation system, which comprises the left auricle occlusion ablation device. Since the left auricle occlusion ablation system comprises the left auricle occlusion ablation device, the procedure of one-stop treatment surgery of 'ablation+left auricle occlusion' is simplified, the difficulty of surgery is reduced, and the success rate of ablation is high. BRIEF DESCRIPTION OF DRAWINGS

[0012] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of the present application, and therefore should not be regarded as a limitation on the scope. Other related drawings can also be obtained by those skilled in the art without creative labor on the basis of these drawings.

[0013] Figure 1 The structure schematic diagram of the left auricle occlusion ablation device provided by the embodiment 1 of the present application;

[0014] Figure 2 A cross-sectional structural schematic view of the left atrial appendage occlusion and ablation device provided for Embodiment 1 of the present application;

[0015] Figure 3 A cross-sectional structural schematic view of the left atrial appendage occlusion and ablation device provided for Embodiment 1 of the present application; Figure 2 A local structural enlarged schematic view at III in the above figure;

[0016] Figure 4 A structural schematic view of the delivery device provided for Embodiment 1 of the present application;

[0017] Figure 5 A structural schematic view of the first skeleton in the left atrial appendage occlusion and ablation device provided for Embodiment 1 of the present application;

[0018] Figure 6 A structural schematic view at the insulation connecting piece in the left atrial appendage occlusion and ablation device provided for Embodiment 2 of the present application;

[0019] Figure 7 A structural schematic view at the insulation connecting piece in the left atrial appendage occlusion and ablation device provided for Embodiment 3 of the present application;

[0020] Figure 8 A structural schematic view at the insulation connecting piece in the left atrial appendage occlusion and ablation device provided for Embodiment 4 of the present application;

[0021] Figure 9 A structural schematic view at the insulation connecting piece in the left atrial appendage occlusion and ablation device provided for Embodiment 5 of the present application;

[0022] Figure 10 A structural schematic view at the insulation connecting piece in the left atrial appendage occlusion and ablation device provided for Embodiment 5 of the present application when the insulation connecting piece is stretched and twisted;

[0023] Figure 11 A structural schematic view of the left atrial appendage occlusion and ablation device provided for Embodiment 6 of the present application;

[0024] Figure 12 A cross-sectional structural schematic view of the left atrial appendage occlusion and ablation device provided for Embodiment 6 of the present application after removing the covering film;

[0025] Figure 13 A structural schematic view of the left atrial appendage occlusion and ablation device provided for Embodiment 7 of the present application;

[0026] Figure 14 A structural schematic view of another left atrial appendage occlusion and ablation device provided for Embodiment 8 of the present application;

[0027] Figure 15 A structural schematic view of the left atrial appendage occlusion and ablation device provided for Embodiment 9 of the present application;

[0028] Figure 16Structure schematic diagram of left atrial appendage occlusion and ablation device of embodiment 9 of the present application after removing the covering;

[0029] Figure 17 Structure schematic diagram of left atrial appendage occlusion and ablation device of embodiment 10 of the present application;

[0030] Figure 18 Structure schematic diagram of left atrial appendage occlusion and ablation device of embodiment 10 of the present application after removing the covering;

[0031] Figure 19 Structure schematic diagram of left atrial appendage occlusion and ablation device of embodiment 11 of the present application;

[0032] Figure 20 Structure schematic diagram of left atrial appendage occlusion and ablation device of embodiment 11 of the present application after removing the covering;

[0033] Figure 21 Structure schematic diagram of left atrial appendage occlusion and ablation device of embodiment 12 of the present application after removing the covering;

[0034] Figure 22 Structure schematic diagram of first skeleton of left atrial appendage occlusion and ablation device of embodiment 12 of the present application;

[0035] Figure 23 Structure schematic diagram of left atrial appendage occlusion and ablation device of embodiment 13 of the present application;

[0036] Figure 24 Structure schematic diagram of left atrial appendage occlusion and ablation device of embodiment 14 of the present application;

[0037] Figure 25 Structure schematic diagram of left atrial appendage occlusion and ablation device of embodiment 14 of the present application after removing the covering.

[0038] Icon: 100 - left atrial appendage occlusion ablation device; 110 - anchor disc; 111 - first skeleton; 112 - support part; 1121 - support rod; 1122 - first branch; 1123 - second branch; 1124 - first connection point; 113 - anchor part; 1131 - connecting rod; 1132 - third branch; 1133 - fourth branch; 1134 - second connection point; 114 - first conductive part; 116 - first electrode piece; 117 - barb; 118 - connecting ring; 119 - distal end connecting piece; 120 - sealing disc; 121 - second skeleton; 122 - second conductive part; 123 - second electrode piece; 124 - second conductive connecting part; 125 - insulating film; 126 - flow resistance film; 127 - disc surface; 128 - disc bottom; 129 - waist part; 130 - insulating connecting piece; 131 - first connecting piece; 1311 - first mounting space; 132 - second connecting piece; 132A - second connecting piece; 132B - second connecting piece; 132C - second connecting piece; 1321 - large tube segment; 1322 - small tube segment; 133 - third connecting piece; 1331 - inner sleeve; 1332 - outer sleeve; 1333 - second mounting space; 134 - first conductive connecting part; 140 - delivery device; 141 - conductive cable; 142 - catheter; 143 - outer tube; 144 - handle. DETAILED DESCRIPTION

[0039] In order to make the objects, technical solutions, and advantages of the embodiments of the present application clearer, the following will be combined with the accompanying drawings for a clear and complete description of the technical solutions in the embodiments of the present application. Obviously, the described embodiments are some but not all of the embodiments of the present application. The components of the embodiments of the present application described and shown in the accompanying drawings can be arranged and designed in various different configurations.

[0040] Therefore, the following detailed description of the embodiments of the present application provided in the accompanying drawings is not intended to limit the scope of the claimed application, but only represents selected embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative work are within the scope of protection of the present application.

[0041] It should be noted that: the same or similar reference numbers and letters represent similar items in the following drawings, therefore, once an item is defined in one drawing, it does not need to be further defined and explained in subsequent drawings.

[0042] In the description of the present application, it should be noted that if the terms "upper", "lower", "inner", "outer" and the like indicate the orientation or positional relationship shown in the drawings, or the orientation or positional relationship commonly used when the product of the present application is used, only for the convenience of describing the present application and simplifying the description, and therefore cannot be understood as indicating or implying that the device or element must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the present application.

[0043] In addition, if the terms "first", "second" and the like appear, they are only used to distinguish the description and cannot be understood as indicating or implying relative importance.

[0044] It should be noted that the features in the embodiments of the present application can be combined with each other without conflict.

[0045] Definition interpretation:

[0046] Left atrial appendage inlet: the position from the left atrium into the left atrial appendage.

[0047] Proximal and distal: after a component is placed, the end closer to the outside of the body is the proximal end of the component; after a component is placed, the end closer to the inside of the body is the distal end of the component. In other words, after the left atrial appendage occlusion and ablation device 100 is implanted in the left atrial appendage, the proximal end of a certain component in the left atrial appendage occlusion and ablation device 100 is the end of the component closer to the left atrium, and the distal end of the component is the end of the component farther away from the left atrium.

[0048] Insulation treatment: forming an insulating layer on the surface of a component, so that the part of the component is insulated. Specifically, the ways of insulation treatment are: coating an insulating coating material at the position where insulation treatment is needed, the coating material includes but is not limited to parylene coating, PTFE coating, PI coating; or covering an insulating film at the position where insulation treatment is needed, the film material includes but is not limited to FEP, PU, ETFE, PFA, PTFE, PEEK, silicone; or threading an insulating sleeve at the position where insulation treatment is needed, the material of the insulating sleeve includes but is not limited to FEP, PU, ETFE, PFA, PTFE, PEEK, silicone.

[0049] The left atrial appendage occlusion and ablation device 100 provided by the embodiment is used for implanting into the left atrial appendage orifice and can perform pulse ablation or radiofrequency ablation on the left atrial appendage tissue. Pulse ablation uses high-intensity pulse electric field to cause irreversible electric breakdown of the cell membrane, which is called irreversible electroporation (IRE) in the medical field, so as to realize non-thermal effect ablation of cells and is not affected by the heat sink effect. The high-voltage pulse sequence produces less heat and does not need to be flushed with physiological saline to cool, which can effectively reduce the occurrence of air explosion, scab and thrombus. The pulse ablation treatment time is short, and the treatment time of a group of pulse sequences is less than 1 minute, and the whole ablation time is generally not more than 5 minutes. And because there are differences in the response threshold of different tissues to the pulse electric field, it provides the possibility of ablation of the myocardium without interfering with other adjacent tissues, so as to avoid accidental injury to the tissues adjacent to the left atrial appendage. In addition, compared with other energies, pulse ablation does not need heat conduction to ablate deep tissues, all myocardial cells distributed above a certain electric field intensity will be electroporated, reducing the requirement for the ablation instrument to adhere to the pressure of the catheter 142. Therefore, even if the ablation instrument does not completely adhere to the inner wall of the left atrial appendage after entering the left atrial appendage, it does not affect the IRE ablation effect. The electrode that emits pulse energy can also collect intracardiac electrical signals. Before ablation, the intracardiac electrocardiogram signal is transmitted to the electrocardiogram synchronizer to synchronize the pulse output in the absolute refractory period of myocardial contraction, so as to not interfere with the heart rate and reduce sudden arrhythmia; after the ablation operation, it can also be judged whether the tissue is completely electrically isolated through the intracardiac signal.

[0050] Embodiment 1

[0051] Figure 1 The structure diagram of the left atrial appendage occlusion and ablation device 100 provided by the embodiment is shown in Figure 2 The structure diagram of the left atrial appendage occlusion and ablation device 100 provided by the embodiment is shown in Figure 2 Compared with Figure 1 The flow blocking film 126 is removed, and Figure 2 The part of the first skeleton 111 in the box where the middle anchor disc 110 is located forms the first conductive part 114, and the part of the second skeleton 121 in the box where the sealing disc 120 is located forms the second conductive part 122. Please refer to Figure 1 and Figure 2The embodiment provides a left atrial appendage occlusion and ablation device 100, which comprises an anchoring disc 110, a sealing disc 120 and an insulating connecting piece 130. The anchoring disc 110 is provided with a first conductive part 114, and the sealing disc 120 is provided with a second conductive part 122, and the first conductive part 114 and the second conductive part 122 are used for transmitting ablation energy to tissue. The two ends of the insulating connecting piece 130 are connected with the anchoring disc 110 and the sealing disc 120 respectively, specifically, the distal end of the insulating connecting piece 130 is connected with the anchoring disc 110, and the proximal end of the insulating connecting piece 130 is connected with the sealing disc 120, and the first conductive part 114 and the second conductive part 122 are electrically isolated through the insulating connecting piece 130. In use, different electric ablation energies are transmitted to the first conductive part 114 and the second conductive part 122 respectively, for example, the first conductive part 114 is electrically connected with the positive output end of an external signal source, and the second conductive part 122 is electrically connected with the negative output end of the external signal source, and the electric field formed between the first conductive part 114 and the second conductive part 122 realizes ablation, and the ablation effect is good. In addition, the insulating performance between the first conductive part 114 and the second conductive part 122 is improved through the insulating connecting piece 130, the possibility of realizing electrical connection between the first conductive part 114 and the second conductive part 122 is reduced, and the ablation success rate and system reliability are improved.

[0052] Meanwhile, in other embodiments, the same electric signal can also be transmitted to the first conductive part 114 and the second conductive part 122 according to requirements.

[0053] Generally, the first skeleton 111 and the second skeleton 121 are both made of metal materials with shape memory and super-elasticity, such as nickel-titanium alloy.

[0054] The left atrial appendage occlusion and ablation device 100 provided by the embodiment is further described below:

[0055] Figure 3 For Figure 2 A local structure enlarged schematic view of the position III, Figure 4 A structure schematic view of a delivery device 140 provided by the embodiment is shown in FIG. 6. Please refer to Figures 1-4 The embodiment further provides a left atrial appendage occlusion and ablation system, which comprises the delivery device 140 and the left atrial appendage occlusion and ablation device 100, the left atrial appendage occlusion and ablation device 100 is used for being loaded at the distal end of the delivery device 140, and the delivery device 140 is used for delivering and releasing the left atrial appendage occlusion and ablation device 100 to a target position, i.e. the left atrial appendage mouth. It can be understood that in some embodiments, the left atrial appendage occlusion and ablation system provided by the application can also be applied to treat other tissue defects.

[0056] The delivery device 140 includes an outer tube 143, a catheter 142, a conductive cable 141, and a handle 144 disposed at the proximal end of the outer tube 143. The distal end of the conductive cable 141 is connected to the anchor 110, so that the conductive cable 141 is used to deliver electrical energy to the first conductive part 114. The distal end of the catheter 142 is connected to the sealing disc 120, and the proximal end of the catheter 142 is electrically connected to an external signal source. Thus, the external signal source transmits electrical energy to the second conductive part 122 through the catheter 142. Specifically, the catheter 142 and the conductive cable 141 are used to connect different output terminals of the external signal source. For example, one of the catheter 142 and the conductive cable 141 is used to connect the positive terminal of the output terminal of the external signal source, and the other is used to connect the negative terminal of the output terminal of the external signal source.

[0057] The proximal end of the sealing disc 120 is detachably connected to the distal end of the catheter 142. The outer tube 143 is sleeved outside the catheter 142. In the delivery state, the distal end of the outer tube 143 is used to accommodate the left atrial appendage occlusion and ablation device 100. During the release of the left atrial appendage occlusion and ablation device 100, the outer tube 143 is withdrawn by the handle 144 to release the left atrial appendage occlusion and ablation device 100. In addition, the conductive cable 141 is provided in a tubular structure. Thus, the inner hole of the conductive cable 141 can be used to guide the traction wire to pass through, so as to facilitate the delivery of the left atrial appendage occlusion and ablation device 100 to the target position.

[0058] The insulating connector 130 is provided with a first conductive connecting part 134, which is used to detachably connect with the conductive cable 141 in the delivery device 140. The conductive cable 141 is electrically connected to the first conductive part 114 through the first conductive connecting part 134, so that the conductive cable 141 is used to deliver ablation energy to the first conductive part 114. After ablation is completed, the conductive cable 141 can be detached from the first conductive connecting part 134. In some embodiments, the insulating connector 130 is in a cylindrical shape, and the first conductive connecting part 134 is disposed on the inner surface of the first connector. Alternatively, the first conductive connecting part 134 is threadedly connected with the conductive cable 141 to achieve detachable connection between the first conductive connecting part 134 and the conductive cable 141. It can be understood that in other embodiments, other ways can be used to achieve detachable connection between the first conductive connecting part 134 and the conductive cable 141 according to requirements, such as magnetic connection or clamping, etc.

[0059] The insulating connecting member 130 extends along the axial direction, and the proximal end of the insulating connecting member 130 is connected to the sealing disc 120, and the distal end of the insulating connecting member 130 is connected to the anchoring disc 110. The insulating axial section in the insulating connecting member 130 achieves the insulating connection between the sealing disc 120 and the anchoring disc 110, thereby improving the insulation performance between the two discs. The "axial section" refers to a section extending along the axial direction of a component and surrounding the axial direction for one turn along the axial direction of the component. In the present embodiment, the left atrial appendage occlusion and ablation device 100 is symmetrical along the axial direction, and the axial direction of the insulating connecting member 130 is the axial direction of the left atrial appendage occlusion and ablation device 100.

[0060] The insulating connecting member 130 includes a first connecting member 131 and at least one second connecting member 132 connected in sequence, i.e., the first connecting member 131 and the at least one second connecting member 132 are connected in sequence along the axial direction. The distal end of the first connecting member 131 is connected to the anchoring disc 110. Among the at least one second connecting member 132, the proximal end of the second connecting member 132 closest to the proximal end is connected to the sealing disc 120.

[0061] In the present embodiment, the insulating connecting member 130 includes a first connecting member 131 and a second connecting member 132 connected in sequence. The anchoring disc 110 is connected to the first connecting member 131. The first connecting member 131 includes a first conductive connecting portion 134, and the first conductive connecting portion 134 is insulatively connected to the second connecting member 132, thereby achieving electrical isolation between the first conductive portion 114 and the second conductive portion 122. The distal end of the sealing disc 120 is connected to the second connecting member 132. Meanwhile, the second connecting member 132 is in a cylindrical shape and is formed with a passage for the conductive cable 141 to pass through. In this way, the conductive cable 141 is connected to the first conductive connecting portion 134 by passing through the passage of the second connecting member 132. In some embodiments, the second connecting member 132 is directly connected to the sealing disc 120. The second connecting member 132 is used to be fixedly connected to the distal end of the sealing disc 120, and to bundle the plurality of nickel-titanium alloy wires in the sealing disc 120.

[0062] Specifically, at least part of the axial section of the first connecting member 131 proximal to the first conductive connecting portion 134 can be provided with an insulating surface, thereby achieving the insulating connection between the first conductive connecting portion 134 and the second connecting member 132.

[0063] For example, the first connecting member 131 is provided with at least a proximal end insulation, and the first conductive connecting part 134 is provided with a thread on the inner wall of the distal end of the first connecting member 131, in which case, the conductive and insulating properties of the second connecting member 132 are not limited. The proximal end of the axial section of the insulation is closer to the proximal end of the first connecting member 131 than the proximal end of the first conductive connecting part 134, and the axial section of the insulation can be provided on the insulating surface of the first connecting member 131, or the material of the first connecting member 131 in the axial section can be insulating. The distal end of the axial section of the insulation is not limited, and in some embodiments, the distal end of the axial section of the insulation is closer to the sealing disc 120 than the proximal end of the first conductive connecting part 134 in the axial direction, or the distal end of the axial section of the insulation is closer to the anchoring disc 110 than the proximal end of the first conductive connecting part 134, or the axial section of the insulation extends through the first connecting member 131.

[0064] In some embodiments, the second connecting member 132 can also be provided with at least partial axial section surface insulation to achieve insulated connection of the first conductive connecting part 134 and the second connecting member 132, for example, the second connecting member 132 is made of insulating material at one end and conductive material at the other end, in which case the conductive properties of the first connecting member 131 except the part of the first conductive connecting part 134 are not limited, and the entire first connecting member 131 can be made of conductive material, and the anchoring part is gathered in the first connecting member 131; or at least partial axial section surface insulation of the first connecting member 131 proximal to the first conductive connecting part 134, and the second connecting member 132 is provided with at least partial axial section surface insulation.

[0065] Further, as shown in Figure 3 the insulation connecting member 130 further comprises a third connecting member 133, the distal end of the sealing disc 120 is gathered in the third connecting member 133, and the proximal end of the second connecting member 132 is connected to the third connecting member 133, that is, in the left atrial appendage occlusion and ablation device 100 shown in the embodiment, the second connecting member 132 is indirectly connected to the sealing disc 120 through the third connecting member 133.

[0066] It can be understood that in other embodiments, the structure of the insulation connecting member 130 can also be specifically set according to needs, for example, the second connecting member 132 is directly connected to the sealing disc 120, in which case the structure of the second connecting member 132 can be set as Figure 3 the structure of the second connecting member 132 and the third connecting member 133 is integrated in the structure shown in the second connecting member 132 in the

[0067] It should also be noted that, in cases such as Figure 3 In the structure shown, the number of second connectors 132 disposed between the first connector 131 and the third connector 133 is one. It can be understood that in some other embodiments, multiple parts may be disposed between the first connector 131 and the third connector 133, that is, in this case, the insulating connector 130 includes multiple second connectors 132.

[0068] Furthermore, the third connector 133 is insulated from the first conductive connector 134, thereby achieving electrical isolation between the first conductive part 114 disposed on the sealing disk 120 and the second conductive part 122 disposed on the anchoring disk 110, that is, the first conductive part 114 and the second conductive part 122 cannot be electrically connected through the insulating connector 130.

[0069] Specifically, the first conductive connection 134 and the third connector 133 can be insulated by setting the first connector 131 to have at least a portion of its axial section surface insulated near the end of the first conductive connection 134. Correspondingly, at least one second connector 132 or at least a portion of its axial section surface can be insulated. Alternatively, at least two or three of the above methods can be set simultaneously to achieve insulation between the first conductive connection 134 and the sealing disc 120, thereby achieving electrical isolation between the first conductive connection 134 and the second conductive part 122.

[0070] In this embodiment, the first connector 131 is made of conductive material, enabling electrical connection between the conductive cable 141 and the first conductive part 114. The conductive cable 141 is electrically connected to the first frame of the anchor plate 110 through the first conductive connection part 134. The second connector 132 is made of insulating material, thereby achieving insulating connection between the second connector 132 and the third connector 133 and the first conductive connection part 134. Thus, the third connector 133 can be configured to be either entirely insulating or entirely conductive as required.

[0071] It should be noted that in this embodiment, the first connector 131 is made entirely of conductive material, and the second connector 132 is made entirely of insulating material. It is understood that in other embodiments, the insulation of each part can be set as needed. For example, the first connector 131 can be set as a cylinder, and the outer surface of the first connector 131 can be set as insulating, while the inner surface of the first connector 131 can be conductive and serve as the first conductive connection part 134. In this way, the first conductive connection part 134 is insulated from the second connector 132 and the third connector 133.

[0072] In the embodiment, the insulating connecting piece 130 is formed with a through cavity for the conductive cable 141 to pass through, and the through cavity extends to the first conductive connecting part 134, so that the conductive cable 141 passing through the through cavity can be electrically connected with the first conductive connecting part 134. Specifically, the insulating connecting piece 130 in the embodiment includes a first connecting piece 131, a second connecting piece 132 and a third connecting piece 133, the first connecting piece 131, the second connecting piece 132 and the third connecting piece 133 are all in a cylindrical shape, and the first connecting piece 131, the second connecting piece 132 and the third connecting piece 133 are sequentially communicated to form the through cavity. Figure 3 The arrow position is the through cavity, and the arrow direction represents the passing direction of the conductive cable 141 in the through cavity during product loading.

[0073] The two parts connected with each other in the insulating connecting piece 130 are detachably connected, that is, in the embodiment, the first connecting piece 131 is detachably connected with the second connecting piece 132, and the second connecting piece 132 is detachably connected with the third connecting piece 133. Alternatively, the first connecting piece 131 is screwed with the second connecting piece 132, and the second connecting piece 132 is screwed with the third connecting piece 133. Specifically, the first connecting piece 131 is provided with a first threaded part, the distal end of the second connecting piece 132 is provided with a second threaded part, and the first threaded part is screwed with the second threaded part to realize the detachable connection of the first connecting piece 131 and the second connecting piece 132. The second connecting piece 132 is screwed with the third connecting piece 133. Specifically, the proximal end of the second connecting piece 132 is provided with a third threaded part, and the third connecting piece 133 is provided with a fourth threaded part, and the third threaded part is screwed with the fourth threaded part.

[0074] Specifically, the second connecting piece 132 includes a large pipe segment 1321 and a small pipe segment 1322 arranged in the axial direction, and the outer diameter of the large pipe segment 1321 is larger than that of the small pipe segment 1322. The first threaded part is an internal thread arranged on the inner wall of the proximal end of the first connecting piece 131, and the second threaded part is an external thread arranged on the outer wall of the small pipe segment 1322. The third threaded part is an internal thread arranged on the inner wall of the large pipe segment 1321, and the fourth threaded part is an external thread arranged on the outer wall of the third connecting piece 133. It can be understood that in other embodiments, the second connecting piece 132 can also be arranged as a single pipe segment with equal diameters at both ends.

[0075] Further, the first connecting member 131 is provided with a first mounting space 1311, and one end of the anchoring disc 110 extends into the first mounting space 1311 and is thus contained in the first mounting space 1311. Specifically, the first connecting member 131 is provided with two annular protrusions that are sleeved with each other, and a receiving groove is formed between the two annular protrusions. The space in the receiving groove is the first mounting space 1311, and the first mounting space 1311 is annular. The receiving groove has an opening facing the distal end, and one end of the anchoring disc 110 extends into the first mounting space 1311 from the opening. It can be understood that in other embodiments, the first connecting member 131 can also be provided as including an inner sleeve and an outer sleeve that are sleeved with each other, and the annular region formed between the inner sleeve and the outer sleeve is the first mounting space 1311. At this time, one of the inner sleeve and the outer sleeve is connected with the second connecting member 132.

[0076] Further, the third connecting member 133 is formed with a second mounting space 1333, and the distal end of the sealing disc 120 is contained in the second mounting space 1333. Specifically, the third connecting member 133 includes an inner sleeve 1331 and an outer sleeve 1332 that are sleeved with each other, and the second mounting space 1333 is formed between the inner sleeve 1331 and the outer sleeve 1332. The second mounting space 1333 is annular. One of the inner sleeve 1331 and the outer sleeve 1332 is connected with the second connecting member 132. In this embodiment, the fourth threaded portion is provided on the outer peripheral wall of the outer sleeve 1332, that is, the outer sleeve 1332 of the third connecting member 133 is connected with the second connecting member 132. It can be understood that in other embodiments, the third connecting member 133 can also be provided as a one-piece structure, and a receiving groove is formed in the third connecting member 133. The space in the receiving groove is the second mounting space 1333.

[0077] Please refer to Figure 1 and Figure 2 In this embodiment, the left atrial appendage occlusion and ablation device 100 includes a support framework, the sealing disc 120 includes a proximal end portion of the support framework, the anchoring disc 110 includes a distal end portion of the support framework, and the first conductive portion 114 and the second conductive portion 122 are part of the support framework. That is, the first conductive portion 114 is at least part of the support framework within the range of the anchoring disc 110, and the second conductive portion 122 is at least part of the support framework within the range of the sealing disc 120.

[0078] Further, the region in the support skeleton corresponding to the first conductive part 114 and the second conductive part 122 is used as an action region, and the region in the support skeleton other than the action region is used as an insulating region. In this embodiment, the support skeleton is made of a conductive material as a whole, and the surface of at least part of the support skeleton corresponding to the insulating region is insulated. Optionally, the surface of at least part of the support skeleton in the insulating region is insulated by using the aforementioned insulating treatment method. For example, the surface of at least part of the support skeleton in the insulating region is coated with an insulating film 125 to achieve surface insulation. That is, the insulating method of the sealing disc 120 is as shown in FIG. 12, or other insulating treatment methods can also be used. It can be understood that in some other embodiments, at least part of the support skeleton in the insulating region can also be made of an insulating material, for example, an insulating biodegradable material. Figure 1

[0079] Specifically, the part of the support skeleton belonging to the anchor disc 110 is the first skeleton 111, that is, the anchor disc 110 includes the first skeleton 111. At least part of the first skeleton 111 is made of a conductive material, which is used as the first conductive part 114 to release ablation energy to the tissue. The part of the support skeleton belonging to the sealing disc 120 is the second skeleton 121, that is, the sealing disc 120 includes the second skeleton 121. In this embodiment, at least part of the second skeleton 121 of the sealing disc 120 is made of a conductive material, which is used as the second conductive part 122 to release ablation energy to the tissue. The first skeleton 111 and the second skeleton 121 are connected by the insulating connecting piece 130. In this embodiment, the first connecting piece 131 is used to bundle the end of the first skeleton 111 in the anchor disc 110, and the third connecting piece 133 is used to bundle the distal end of the second skeleton 121 in the sealing disc 120.

[0080] ​In the embodiment, the first skeleton 111 is made of metal material as a whole, and part of the surface thereof is used as the first conductive part 114, i.e., the part of the first skeleton 111 used as the first conductive part 114 is not insulated, and the surface of the remaining part is insulated, so as to insulate the surface of the part and avoid the problem that the conductive area of the first conductive part 114 is too large and affects the ablation effect. Since the first skeleton 111 is made of metal material, the first connecting piece 131 is conductive as a whole, and the first conductive part 114 and the first conductive connecting part 134 can be directly electrically connected through the first skeleton 111. It can be understood that in some other embodiments, only part of the first skeleton 111 can be made of metal material, and the remaining part can be made of insulating material, so as to insulate the surface of the part, and thus an additional wire needs to be provided to electrically connect the first conductive connecting part 134 and the first conductive part 114. Further, the part of the first skeleton 111 used to abut against the inner wall tissue position of the left atrial appendage is used as the first conductive part 114, and the first conductive part 114 is annular, so that the ablation zone corresponding to the first conductive part 114 is annular, which helps to improve the ablation effect of the left atrial appendage. The outer periphery of the first conductive part 114 is covered with a flow resistance film 126, and the flow resistance film 126 has apertures, so that the flow resistance film 126 can at least filter thrombus, i.e., avoid the thrombus in the left atrial appendage from entering the left atrium, and also ensure that the first conductive part 114 can release ablation energy to the tissue.

[0081] It should be noted that in the embodiment, part of the first skeleton 111 is used as the first conductive part 114, and the surface of the remaining part is insulated. It can be understood that in some other embodiments, the entire first skeleton 111 can be used as the first conductive part 114 at the same time, so as to release ablation energy to the tissue.

[0082] As for the sealing disc 120, the second skeleton 121 is made of metal material as a whole, and part of the second skeleton 121 is used as the second conductive part 122, i.e., the part of the second skeleton 121 used as the second conductive part 122 is not insulated, and the surface of the remaining part is insulated.

[0083] It should be noted that in the embodiment, the part of the second skeleton 121 that needs to be insulated is insulated by insulation treatment. In the embodiment, the sealing disc 120 is further provided with a first insulating film and a second insulating film, the first insulating film and the second insulating film are respectively wrapped on the inner and outer sides of the two ends of the second skeleton 121 in the proximal-to-distal direction, and the part of the second skeleton 121 between the first insulating film and the second insulating film that is not wrapped by the insulating film is used as the second conductive part 122, and the second conductive part 122 is annular and extends in the circumferential direction around the sealing disc 120.

[0084] It should be noted that in the embodiment, part of the second skeleton 121 is used as the second conductive part 122, and the rest of the surface is insulated. It can be understood that in some other embodiments, the entire second skeleton 121 can be used as the second conductive part 122 to release ablation energy to the tissue.

[0085] Optionally, the second conductive part 122 is a position of the second skeleton 121 for abutting the tissue of the left atrial appendage, and the second conductive part 122 is an annular structure extending along the circumference of the second skeleton 121, so as to form an annular ablation zone around the left atrial appendage inlet through the second conductive part 122, thereby improving the ablation effect of the left atrial appendage. In the embodiment, the second skeleton 121 is a double-layer mesh disc made of wire weaving, which includes a proximal skeleton and a distal skeleton, the proximal skeleton is located on one side of the proximal end of the distal skeleton, and the proximal skeleton is connected with the distal skeleton at the circumference. The second conductive part 122 is located on the distal skeleton and is distributed at a position with a larger radial dimension on the distal skeleton, which abuts the tissue of the left atrial appendage inlet, so as to achieve ablation of the tissue at the position. Optionally, the axial projection of the outer shape of the sealing disc 120 is a trapezoidal shape, so as to match the anatomical structure of the left atrial appendage inlet position, and the left atrial appendage inlet is closed by the sealing disc 120.

[0086] It should be noted that in the embodiment, the second skeleton 121 is made of wire weaving, and it can be understood that in some other embodiments, the second skeleton 121 can be made in other ways according to requirements, for example, by cutting a pipe material.

[0087] Please refer to Figures 1-4 In the embodiment, the sealing disc 120 further includes a second conductive connection part 124, the proximal end of the second skeleton 121 is connected with the second conductive connection part 124, and specifically, the proximal end of the second skeleton 121 is gathered at the second conductive connection part 124. The second conductive connection part 124 is used for detachably connecting with a catheter 142, and an external signal source is electrically connected to the second conductive part 122 through the catheter 142 and the second conductive connection part 124 in sequence. Specifically, the second conductive connection part 124 is an annular structure, and the catheter 142 is detachably connected with the second conductive connection part 124. In this way, when the left atrial appendage occlusion and ablation device 100 is released at the left atrial appendage under the action of a delivery device, the implantation of the left atrial appendage occlusion and ablation device 100 is completed, and after ablation, the catheter 142 can be detached from the sealing disc 120, so as to leave the left atrial appendage occlusion and ablation device 100 in the left atrial appendage, and the catheter 142 and the conductive cable 141 are withdrawn from the body.

[0088] Optionally, the second conductive connecting part 124 is threadedly connected with the catheter 142. Specifically, the inner wall of the second conductive connecting part 124 is provided with a sixth threaded part, so that the detachable connection between the second conductive connecting part 124 and the sixth threaded part is realized through the threading of the sixth threaded part and the catheter 142. It can be understood that in other embodiments, the detachable connection between the second conductive connecting part 124 and the catheter 142 can also be realized by magnetic connection or clamping, etc. according to requirements.

[0089] Please refer to Figure 1 In the embodiment, the sealing disc 120 further comprises a flow-blocking film 126 arranged on the second framework 121. Specifically, in the embodiment, the flow-blocking film 126 is arranged radially inside the second framework 121. In other embodiments, the flow-blocking film 126 can also be arranged on the outside of the second framework 121, or even on both the inside and the outside of the second framework 121. The flow-blocking film 126 can at least be used to block the thrombus in the left atrial appendage from flowing out, and according to the porosity of the flow-blocking film 126, the flow-blocking film 126 can even block the blood flow in the left atrial appendage from flowing into the left ventricle. Specifically, since the second framework 121 of the sealing disc 120 is a mesh structure with a plurality of mesh holes formed thereon, the mesh holes are closed by arranging the flow-blocking film 126, so as to block the thrombus at the distal end of the flow-blocking film 126 from moving proximally, so as to avoid the thrombus in the left atrial appendage from entering the left ventricle.

[0090] The distal end of the anchoring disc 110 is provided with a flow-blocking film 126 having a flow-blocking effect. The flow-blocking film 126 is arranged at the distal end of the first framework 111, so as to help block the thrombus at the distal end of the anchoring disc 110 from moving towards the sealing disc 120. Further, the flow-blocking film 126 on the anchoring disc 110 is arranged in a structure with holes, so that the first conductive part 114 can release ablation energy to the tissue. It should be noted that in some embodiments, the material of the flow-blocking film 126 and the material used for insulation treatment can be the same.

[0091] Figure 5 A structure schematic view of the first framework 111 of the left atrial appendage occlusion and ablation device 100 provided in the embodiment is shown in FIG. 6. Please refer to Figure 1 and Figure 5 In the embodiment, the first framework 111 comprises a plurality of support parts 112 and a plurality of anchoring parts 113. The plurality of anchoring parts 113 are arranged around the outer periphery of the plurality of support parts 112.

[0092] Each support part 112 includes a support rod 1121, and a first branch 1122 and a second branch 1123 arranged at one end of the support rod 1121, both the first branch 1122 and the second branch 1123 are in the shape of a rod, thus the outer shape of the support part 112 is approximately Y-shaped. Specifically, the support rod 1121 includes opposite first and second ends, the first ends of the plurality of support rods 1121 are connected to the insulating connecting piece 130, the second ends of the plurality of support rods 1121 spread outward in the radial direction, forming a shape similar to a horn, and the first branch 1122 and the second branch 1123 are connected at the second ends of the corresponding support rods 1121. In this embodiment, the first end is the proximal end of the support rod 1121, and the second end is the distal end of the support rod 1121. It can be understood that in alternative embodiments, the first end is not limited to the proximal end of the support rod 1121, and the second end is not limited to the distal end of the support rod 1121.

[0093] The end of each first branch 1122 away from the support rod 1121 is connected to the end of the second branch 1123 of the adjacent support part 112 away from the support rod 1121, and the connection forms a first connection point 1124. Each anchor part 113 is connected to the corresponding first connection point 1124 and extends towards the proximal end. The first skeleton 111 thus formed is a double-layer structure, the plurality of support rods 1121 surround the inner layer forming the first skeleton 111, and the plurality of anchor parts 113 surround the outer layer forming the first skeleton 111. In the first skeleton 111, the part of the anchor part 113 used to abut the tissue of the inner wall of the left atrial appendage serves as a first conductive part 114, and the first conductive part 114 is annular, thereby forming an annular ablation zone extending circumferentially along the first skeleton 111 through the first conductive part 114.

[0094] Optionally, the first skeleton 111 further includes a connecting ring 118, the proximal ends of the plurality of support rods 1121 are connected to the connecting ring 118, thereby connecting the proximal ends of the plurality of support rods 1121 together. When the anchor disc 110 is connected to the insulating connecting piece 130, the connecting ring 118 is accommodated in the first mounting space 1311, thereby bundling the proximal end of the inner layer of the first skeleton 111 in the first mounting space 1311. It can be understood that in some other embodiments, the connecting ring 118 can not be provided, and the proximal end of the support rod 1121 can be directly bundled and limited in the first mounting space 1311 to achieve the connection between the anchor disc 110 and the insulating connecting piece 130. Optionally, the connecting ring 118, the plurality of support parts 112 and the plurality of anchor parts 113 are integrally made by cutting a pipe material.

[0095] Further, the plurality of anchors 113 are divided into groups, each group of anchors 113 comprising two adjacent anchors 113, and the proximal ends of the two anchors 113 in each group of anchors 113 are connected, thereby forming a grid structure. Further, in each group of anchors 113, the connection between the two anchors 113 extends in a direction of the axis of the first skeleton 111, i.e., inwardly, in a hook shape, thereby reducing the irritation and damage of the tissue by the ends of the anchors.

[0096] Further, the anchoring disc 110 further comprises barbs 117 disposed radially outward of the first skeleton 111, the distal ends of the barbs 117 being connected to the anchors 113, and the proximal ends of the barbs 117 being located radially outward of the first skeleton 111. Specifically, the barbs 117 are connected to the anchors 113, and after the left atrial appendage occlusion and ablation device 100 is implanted in the left atrial appendage, the barbs 117 are inserted into the tissue of the left atrial appendage, thereby preventing the anchoring disc 110 from detaching from the tissue of the left atrial appendage.

[0097] The left atrial appendage occlusion and ablation device 100 according to the present embodiment has the following working principle:

[0098] The first conductive connection 134 of the left atrial appendage occlusion and ablation device 100 is connected to the conductive cable 141, and the second conductive connection 124 is connected to the catheter 142. Before use, the left atrial appendage occlusion and ablation device 100 is in a compressed state and is contained in the delivery device. During use, the left atrial appendage occlusion and ablation device 100 is delivered and released into the left atrial appendage of the body by the delivery device 140. At this time, the anchoring disc 110 of the left atrial appendage occlusion and ablation device 100 is in an expanded state and is anchored in the left atrial appendage, and the barbs 117 of the anchoring disc 110 are inserted into the tissue of the left atrial appendage. The sealing disc 120 of the left atrial appendage occlusion and ablation device 100 is in an expanded state and is located at the entrance of the left atrial appendage, so as to close the left atrial appendage by the sealing disc 120.

[0099] After implantation, an external energy source successively delivers electric ablation energy to the second conductive part 122 through the catheter 142 and the second conductive connection 124, and the conductive cable 141 delivers electric ablation energy to the first conductive part 114 through the first conductive connection 134. The electric ablation energy of the first conductive part 114 and the second conductive part 122 is different. For example, if the first conductive part 114 is electrically connected to the positive electrode of the external signal source, the second conductive part 122 is electrically connected to the negative electrode of the external signal source. If the first conductive part 114 is electrically connected to the negative electrode, the second conductive part 122 is electrically connected to the positive electrode. In this way, an electric field is formed between the first conductive part 114 and the second conductive part 122 to achieve ablation, and the ablation effect is good. After ablation, the first conductive connection 134 is disconnected from the conductive cable 141, and the second conductive connection 124 is disconnected from the catheter 142, so as to withdraw the conductive cable 141 and the catheter 142 from the body, and the left atrial appendage occlusion and ablation device 100 is left in the patient's body.

[0100] The left atrial appendage occlusion and ablation device 100 provided in this embodiment has at least the following advantages:

[0101] The left atrial appendage occlusion and ablation device 100 provided in this embodiment realizes the connection of the anchor disc 110 and the sealing disc 120 by arranging the insulating connecting piece 130, so as to realize the electrical isolation of the first conductive part 114 on the anchor disc 110 and the second conductive part 122 on the sealing disc 120, and the insulation effect is good, thereby helping to improve the success rate of ablation. At the same time, the first conductive part 114 transmits electric energy through the conductive cable 141 which is detachably connected with the first conductive connecting part 134, and the second conductive part 122 transmits electric energy through the catheter 142 which is detachably connected with the second conductive connecting part 124, and after the ablation is completed, the conductive cable 141 and the catheter 142 can be easily withdrawn from the body, without the need to cut the wire. Moreover, the first skeleton 111 and the second skeleton 121 are partially used as conductive parts, and the remaining parts are insulated on the surface, so as to reduce the discharge area and improve the ablation effect.

[0102] Embodiment 2

[0103] Figure 6 The structure schematic diagram of the insulating connecting piece 130 in the left atrial appendage occlusion and ablation device 100 provided in this embodiment is shown. This embodiment also provides a left atrial appendage occlusion and ablation device 100, and the main difference between the left atrial appendage occlusion and ablation device 100 provided in this embodiment and the left atrial appendage occlusion and ablation device 100 provided in Embodiment 1 is that the structure of the insulating connecting piece 130 is different.

[0104] In this embodiment, the parts connected to each other in the insulating connecting piece 130 are in interference fit, so that the parts connected to each other in the insulating connecting piece 130 are detachably connected. That is, the first connecting piece 131 and the second connecting piece 132 are in interference fit, and the second connecting piece 132 and the third connecting piece 133 are in interference fit. It can be understood that in other embodiments, the connection mode between the first connecting piece 131 and the second connecting piece 132 can also be arranged to be different from the connection mode between the second connecting piece 132 and the third connecting piece 133.

[0105] Specifically, the inner peripheral wall of the proximal end of the first connecting piece 131 is in interference fit with the outer peripheral wall of the small tube segment 1322 of the second connecting piece 132. The inner peripheral wall of the large tube segment 1321 of the second connecting piece 132 is in interference fit with the outer peripheral wall of the outer sleeve 1332 of the third connecting piece 133.

[0106] Embodiment 3

[0107] Figure 7A structure schematic diagram of the insulation connecting piece 130 in the left atrial appendage occlusion and ablation device 100 provided in the present embodiment is shown. The present embodiment also provides a left atrial appendage occlusion and ablation device 100, which is mainly different from the left atrial appendage occlusion and ablation device 100 provided in Embodiment 1 in that the structure of the insulation connecting piece 130 is different.

[0108] In the present embodiment, the parts connected to each other in the insulation connecting piece 130 are clamped, so that the parts connected to each other in the insulation connecting piece 130 are detachably connected. That is, the first connecting piece 131 is clamped with the second connecting piece 132, and the second connecting piece 132 is clamped with the third connecting piece 133.

[0109] Specifically, the first connecting piece 131 is provided with a clamping groove, and the distal end of the second connecting piece 132 is provided with a clamping wedge. The first connecting piece 131 is clamped with the second connecting piece 132 through the clamping of the clamping groove and the clamping wedge, so that the first connecting piece 131 and the second connecting piece 132 are stopped in the direction from the proximal end to the distal end. The proximal end of the second connecting piece 132 is provided with a clamping groove, and the outer side of the third connecting piece 133 is provided with a clamping wedge. The second connecting piece 132 is clamped with the third connecting piece 133 through the clamping of the clamping groove of the second connecting piece 132 and the clamping wedge of the third connecting piece 133, so that the second connecting piece 132 and the third connecting piece 133 are stopped in the direction from the proximal end to the distal end.

[0110] It should be noted that the specific structure of the clamping is not limited here. It can be understood that in other embodiments, other structures can also be used to realize the clamping cooperation between the parts connected to each other in the insulation connecting piece 130 according to requirements.

[0111] Embodiment 4

[0112] Figure 8 A structure schematic diagram of the insulation connecting piece 130 in the left atrial appendage occlusion and ablation device 100 provided in the present embodiment is shown. The present embodiment also provides a left atrial appendage occlusion and ablation device 100, which is mainly different from the left atrial appendage occlusion and ablation device 100 provided in Embodiment 1 in that the structure of the insulation connecting piece 130 is different.

[0113] In the present embodiment, the parts connected to each other in the insulation connecting piece 130 are clamped, so that the parts connected to each other in the insulation connecting piece 130 are detachably connected. That is, the first connecting piece 131 is clamped with the second connecting piece 132, and the second connecting piece 132 is clamped with the third connecting piece 133.

[0114] Specifically, the proximal end and the distal end of the second connecting member 132 are respectively provided with a pivot slot, the proximal end of the first connecting member 131 is provided with a first pivot joint, and the first connecting member 131 is pivoted with the distal end of the second connecting member 132 through the first pivot joint and the pivot slot of the distal end of the second connecting member 132; the distal end of the third connecting member 133 is provided with a second pivot joint, and the first connecting member 131 is pivoted with the proximal end of the second connecting member 132 through the second pivot joint and the pivot slot of the proximal end of the second connecting member 132.

[0115] It should be noted that the insulating connecting member 130 in the embodiment is provided with a through hole in the axial direction to form a cavity, so that components such as catheters or guide wires can pass through.

[0116] Example 5

[0117] Figure 9 The structure schematic diagram of the insulating connecting member 130 in the left atrial appendage occlusion and ablation device 100 provided in the embodiment is provided. The embodiment also provides a left atrial appendage occlusion and ablation device 100, which is mainly different from the left atrial appendage occlusion and ablation device 100 provided in the embodiment 1 in that the structure of the insulating connecting member 130 is different.

[0118] In the embodiment, the parts connected to each other in the insulating connecting member 130 are flexibly connected, so that the first connecting member 131 and the second connecting member 132 can be flexibly connected, and the second connecting member 132 and the third connecting member 133 can be flexibly connected. Specifically, the second connecting member 132 is a flexible rubber structure as a whole, the proximal end of the first connecting member 131 is provided with a first connecting head, the distal end of the third connecting member 133 is provided with a second connecting head, the second connecting member 132 is vulcanized and formed between the first connecting head and the second connecting head, and the distal end of the second connecting member 132 covers the first connecting head and the distal end of the second connecting member 132 covers the second connecting head, so that the anchor disc 110 connected to the first connecting member 131 and the sealing disc 120 connected to the third connecting member 133 can be relatively stretched and twisted (as shown in Figure 10

[0119] It should be noted that in the embodiment, the second connecting member 132 is directly formed on the first connecting head and the second connecting head by vulcanization, and the connection between the second connecting member 132 and the first connecting member 131 and the third connecting member 133 is not detachable. It can be understood that in other embodiments, other ways can also be used to realize the flexible detachable connection between the parts according to the needs.

[0120] It should be noted that the insulating connecting member 130 in the embodiment is provided with a through hole in the axial direction to form a cavity, so that components such as catheters or guide wires can pass through.

[0121] Example 6

[0122] ​Figure 11 A structural schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in the embodiment, Figure 12 A cross-sectional structural schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in the embodiment without the flow blocking film 126 and the insulating film 125. The embodiment also provides a left atrial appendage occlusion and ablation device 100, which is mainly different from the left atrial appendage occlusion and ablation device 100 provided in Embodiment 1 in that the first conductive part 114 and the second conductive part 122 are formed in different ways.

[0123] In the embodiment, the first conductive part 114 and the second conductive part 122 are electrode members arranged on the support framework. Specifically, the anchoring disc 110 further comprises a first electrode member 116 arranged on the first framework 111, so that the first electrode member 116 is used as the first conductive part 114, and the surface of at least the part of the first framework 111 not corresponding to the first electrode member 116 is insulated, that is, the anchoring disc 110 can be arranged such that only the surface of the part of the first framework 111 not corresponding to the first electrode member 116 is insulated, or the surface of the entire first framework 111 can be insulated.

[0124] In the embodiment, the anchoring disc 110 is provided with the flow blocking film 126, and the first electrode member 116 is located outside the flow blocking film 126, that is, the flow blocking film 126 is arranged between the first electrode member 116 and the first framework 111, and the part of the first framework 111 corresponding to the first electrode member 116 can be regarded as the projection part of the first electrode member 116 on the anchoring part 113. As shown in the figure, in the case where the flow blocking film 126 is omitted from the anchoring disc 110, the part of the first framework 111 corresponding to the first electrode member 116 is the part of the first framework 111 in contact with the first electrode member 116, and correspondingly, the part of the first framework 111 not corresponding to the first electrode member 116 is the part of the first framework 111 not in contact with the first electrode member 116. Figure 14

[0125] The first conductive part 114 extends along the circumferential bending of the left atrial appendage ablation device. In the embodiment, the first electrode member 116 extends along the circumferential bending of the first framework 111, so that the first electrode member 116 arranged on the outer periphery of the first framework 111 extends in a certain range in the axial direction of the first framework 111, and further, the ablation area formed by the first electrode member 116 extends in a strip shape along the axial direction of the first framework 111.

[0126] Specifically, the first electrode member 116 is a sawtooth structure formed by bending an electrode wire. It can be understood that in other embodiments, the first electrode member 116 can also be arranged in other shapes extending by bending, such as a wave shape.

[0127] ​Optionally, the first electrode member 116 is an electrode wire or an electrode strip. It can be understood that the type of the first electrode member 116 can also be selected according to requirements, for example, the first electrode member 116 can be provided as a rod-shaped electrode, an array ring-shaped electrode or a ring-shaped ablation catheter, etc. Optionally, the first electrode member 116 extends to the first conductive connecting portion 134 and is connected to the first conductive connecting portion 134 by welding, so as to realize the electrical connection between the first electrode member 116 and the first conductive connecting portion 134.

[0128] In the embodiment, the first electrode member 116 is electrically connected to the first skeleton 111 in the action area, and a hole can be arranged in the flow resistance film 126 between the first electrode member 116 and the first skeleton 111 to ensure the electrical conduction between the first electrode member 116 and the first skeleton 111. In an embodiment, the first connecting member 131 is surface-insulated, and / or the first skeleton 111 is surface-insulated, and the first electrode member 116 extends to the first conductive connecting portion or is connected to the first conductive connecting portion by a wire to transmit the ablation energy.

[0129] It should be noted that the insulating connecting member 130 in the left atrial appendage occlusion and ablation device 100 provided in the embodiment is the structure of the insulating connecting member 130 provided in Embodiment 1. It can be understood that the structure of the insulating connecting member 130 provided in Embodiments 2-6 can also be adopted.

[0130] Embodiment 7

[0131] Figure 13 The structure schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in the embodiment is provided. The embodiment also provides a left atrial appendage occlusion and ablation device 100, and the main difference between the left atrial appendage occlusion and ablation device 100 provided in the embodiment and the left atrial appendage occlusion and ablation device 100 provided in Embodiment 1 is that the structure of the insulating connecting member 130 is different.

[0132] In the embodiment, the number of the second connecting members is two, and the two second connecting members are respectively a second connecting member 131A and a second connecting member 131B. The second connecting member 131A and the second connecting member 131B are connected in sequence along the axial direction, and the second connecting member 131A is arranged at the distal end of the second connecting member 131B. The second connecting member 132B is connected to the third connecting member 133, the second connecting member 132A is connected to the first connecting member 131, and the anchor disc 110 is gathered at the second connecting member 132A. Specifically, the first mounting space 1311 is arranged at the second connecting member 132A.

[0133] The first connecting member 131 and the third connecting member 133 are integrally made of conductive material, that is, the first connecting member 131 is a first conductive connecting part 134, and the second connecting member 132A and the second connecting member 132B are at least surface insulated to realize insulated connection between the first conductive connecting part 134 and the third connecting member 133. In this embodiment, the second connecting member 132A and the second connecting member 132B are integrally made of insulating material. It can be understood that in some other embodiments, the second connecting member 132A and the second connecting member 132B can be one part, that is, integrally formed, or can realize insulated connection between the third connecting member 133 and the first conductive connecting part 134 by other means.

[0134] Embodiment 8

[0135] Figure 14 The structure of another left atrial appendage occlusion and ablation device 100 provided by this embodiment is shown, for the sake of clarity, Figure 14 The membrane structure of the left atrial appendage occlusion and ablation device 100 is omitted, such as the flow blocking membrane and the insulating membrane. The insulating connecting member 130 provided by this embodiment is suitable for the embodiment in which the first conductive part is the first electrode member 116.

[0136] Please refer to Figure 14 In this example, the number of second connecting members 132 is three, which are sequentially connected in the axial direction from the distal end to the proximal end, and are respectively the second connecting member 132A, the second connecting member 132B, and the second connecting member 132C. The second connecting member 132B in the middle is conductive, and the second connecting member 132A and the second connecting member 132C located at both ends of the second connecting member 132B are at least partially insulated, that is, they can be integrally insulated. In a preferred embodiment, the first connecting member 131 is integrally conductive (that is, the first connecting member 131 is a first conductive connecting part 134), the second connecting member 132A is integrally insulated, the second connecting member 132B is integrally conductive, the second connecting member 132C is integrally insulated, and the third connecting member 133 is integrally conductive.

[0137] The second connecting member 132B is used to bind the first skeleton, and the third connecting member 133 is used to bind the second skeleton. The second connecting member 132B and the third connecting member 133 are made of conductive metal material, which can firmly bind the skeleton and is beneficial to improve the mechanical properties of the sealing disc 120 and the anchoring disc 110.

[0138] The second connecting member 132C is integrally insulated to electrically isolate the sealing disc 120 and the anchoring disc 110.

[0139] The first connecting member 131 is conductive as a whole, or at least the first conductive connecting part is conductive, for electrically connecting with the first electrode member 116 arranged on the periphery of the anchoring disc 110. The first electrode member 116 directly extends to the first conductive connecting part, or is connected to the first conductive connecting part through an additional wire.

[0140] The second connecting member 132A is insulating as a whole, for isolating the two ends of the second connecting member 132A from the first connecting member 131, so that the first skeleton in the anchoring disc 110 is electrically isolated from the first conductive connecting part and the first electrode member 116. When the first electrode member 116 is conductive, the first skeleton is insulating, thus, without discussing the specific form of the second conductive part on the sealing disc 120, the distance between the conductive part on the anchoring disc 110 and the sealing disc 120 is increased, and the insulation performance between the sealing disc 120 and the anchoring disc 110 is improved. In the case where the insulation treatment on the surface of the first skeleton 111 is damaged, the insulation between the sealing disc 120 and the anchoring disc 110 can still be ensured, so as to realize the insulation between the first conductive part and the second conductive part.

[0141] Embodiment 9

[0142] Figure 15 A structure schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in the embodiment is shown in the figure, Figure 16 A structure schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in the embodiment is shown in the figure,

[0143] In the embodiment, the first skeleton 111 of the anchoring disc 110 is made of wire weaving, and the distal ends of the first skeleton 111 are connected together radially inwardly, so that the first skeleton 111 is in a cage shape. Specifically, the anchoring disc 110 further comprises a distal end connecting member 119 arranged at the distal end of the anchoring disc 110. The distal ends of the wires woven to form the first skeleton 111 are radially inwardly gathered at the distal end connecting member 119, and the distal end connecting member 119 is located inside the cage formed by the wires.

[0144] Meanwhile, in the left atrial appendage occlusion and ablation device 100 shown in the embodiment, the sealing disc 120 is conductive through the second skeleton 121 to form the second conductive part 122, and the anchoring disc 110 is provided with the first electrode member 116, which is used as the first conductive part 114 to transmit the ablation energy.

[0145] Embodiment 10

[0146] Figure 17A structure schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in the embodiment, Figure 18 A structure schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in the embodiment without the covering film (such as the flow blocking film and the insulating film). The embodiment also provides a left atrial appendage occlusion and ablation device 100, which is mainly different from the left atrial appendage occlusion and ablation device 100 provided in the embodiment 1 in the structure of the anchoring disc 110 and the structure of the second conductive part 122.

[0147] In the embodiment, the first skeleton 111 of the anchoring disc 110 is made of wire weaving, and the woven first skeleton 111 is double-layered inside and outside. Specifically, the metal wire extends from the proximal end to the distal end of the anchoring disc 110 to form the inner layer of the first skeleton 111, and then folds back from the distal end to the proximal end to weave the outer layer of the first skeleton 111.

[0148] In the embodiment, the sealing disc 120 further comprises a second electrode piece 123 arranged on the second skeleton 121, so that the second electrode piece 123 is used as the second conductive part 122, and the surface of at least the part of the second skeleton 121 not corresponding to the second electrode piece 123 is insulated, that is, the sealing disc 120 can be arranged to only insulate the surface of the part of the second skeleton 121 not corresponding to the second electrode piece 123, or can be arranged to insulate the surface of the whole second skeleton 121. Specifically, the surface insulation of the second skeleton 121 is realized by arranging an insulating film 125 on the second skeleton 121. The part of the second skeleton 121 corresponding to the second electrode piece 123 is the part of the second skeleton 121 in contact with the second electrode piece 123, and correspondingly, the part of the second skeleton 121 not corresponding to the second electrode piece 123 is the part of the second skeleton 121 not in contact with the second electrode piece 123. It can be understood that in other embodiments, the second electrode piece 123 can also be arranged in a circumferentially folded structure, such as a zigzag shape, a wave shape, etc.

[0149] Specifically, the second skeleton 121 is a wire woven structure, and the sealing disc 120 comprises a disc surface 127 facing away from the anchoring disc 110, a disc bottom 128 facing towards the anchoring disc 110, and a waist part 129 connected between the disc surface 127 and the disc bottom 128. The diameter of the disc surface 127 is greater than the diameter of the disc bottom 128, and the diameter of the disc surface 127 is slightly greater than the inner diameter of the left atrial appendage. After implantation, the disc surface 127 presses the left atrial appendage outlet, the disc bottom 128 is inserted into the left atrial appendage, and the diameter of the disc bottom 128 is substantially the same as the inner diameter of the left atrial appendage. The second electrode piece 123 is arranged at the waist part 129 of the sealing disc 120, so as to be in close contact with the left atrial appendage opening.

[0150] Meanwhile, in the left atrial appendage occlusion and ablation device 100 shown in this embodiment, the first conductive part on the anchor disc 110 is part of the first framework 111, and the second conductive part on the sealing disc 120 is the second electrode piece 123 arranged on the second framework 121. It can be understood that the framework or the electrode piece can also be selected according to the needs.

[0151] Embodiment 11

[0152] Figure 19 The structure schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in this embodiment is shown in Figure 20 The structure schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in this embodiment is shown in

[0153] In this embodiment, the first framework 111 of the anchor disc 110 is made of metal wire weaving, and the first framework 111 of the anchor disc 110 in the first embodiment is cut from a pipe material. The first framework and the second framework in this application are not limited to the manufacturing process, and the first framework can be woven or cut, and the second framework can be woven or cut.

[0154] As shown in Figures 19-20 The distal end of the first framework 111 is open, that is, the distal end of the first framework 111 has an opening, so that the outer shape of the first framework 111 is cup-shaped.

[0155] Meanwhile, in the left atrial appendage occlusion and ablation device 100 shown in this embodiment, the first conductive part on the anchor disc 110 and the second conductive part on the sealing disc 120 can be selected according to the needs of the framework or the additional electrode piece.

[0156] Embodiment 12

[0157] Figure 21 The structure schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in this embodiment is shown in Figure 22 The structure schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in this embodiment is shown in

[0158] In the embodiment, the anchoring disc 110 is made by cutting a pipe material. Different from the first skeleton 111 of the embodiment, the two adjacent anchoring portions 113 of the first skeleton 111 are independently arranged in the embodiment, that is, any anchoring portion 113 is not directly connected with other anchoring portions 113. The anchoring portion 113 extends in the proximal direction in a rod shape, and the end of the anchoring portion 113 away from the first connecting point 1124 is bent inward.

[0159] Similarly, the first conductive portion and the second conductive portion of the left atrial appendage occlusion and ablation device 100 provided in the embodiment can also be made in the form of a skeleton or provided with an additional electrode according to requirements.

[0160] Embodiment 13

[0161] Figure 23 A structural schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in the embodiment is shown. The embodiment also provides a left atrial appendage occlusion and ablation device 100, which is mainly different from the left atrial appendage occlusion and ablation device 100 provided in the embodiment 1 in that the structure of the anchoring disc 110 is different, specifically, the structure of the anchoring portion 113 is different from that of the embodiment 1.

[0162] In the embodiment, the anchoring disc 110 is made by cutting a pipe material, and each anchoring portion 113 includes a third branch 1132 and a fourth branch 1133 connected at the distal end, the connection between the third branch 1132 and the fourth branch 1133 forms a second connecting point 1134, and the second connecting point 1134 is connected with the first connecting point 1124. Meanwhile, the proximal end of each third branch 1132 is connected with the proximal end of the fourth branch 1133 of the adjacent anchoring portion 113, so that a grid structure is formed between the two adjacent anchoring portions 113.

[0163] Further, the anchoring portion 113 also includes a connecting rod 1131, the two ends of the connecting rod 1131 are connected with the first connecting point 1124 and the second connecting point 1134 respectively, so that the grid structure formed between the two adjacent anchoring portions 113 is in the form of a hexagon. The barb 117 is arranged on the connecting rod 1131. The first conductive portion is an electrode wire wound on the first branch 1122 and the second branch 1123. Specifically, part of the electrode wire is spirally wound along the circumference of the first branch 1122 so as to be wound on the first branch 1122, and another part of the electrode wire is spirally wound along the circumference of the second branch 1123 so as to be wound on the second branch 1123. It can be understood that in other embodiments, other forms of the first conductive portion 114 can also be used, for example, the structure of the first conductive portion 114 provided in the embodiment 1 or the embodiment 7.

[0164] Embodiment 14

[0165] Figure 24 A structural schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in the embodiment is shown.Figure 25 The structure schematic diagram of the left atrial appendage occlusion and ablation device 100 provided in the embodiment is shown in the figure. The left atrial appendage occlusion and ablation device 100 provided in the embodiment is mainly different from the left atrial appendage occlusion and ablation device 100 provided in the embodiment 1 in the structure of the support framework.

[0166] In the embodiment, the support framework is a three-disc structure, and the first conductive part 114 and the second conductive part 122 are arranged on any two of the three discs respectively. Meanwhile, the first conductive part and the second conductive part can be selected according to the requirement.

[0167] Similarly, the left atrial appendage occlusion and ablation device 100 provided in the embodiment can also adopt the related structure in other embodiments. Specifically, the three discs of the support framework are a first disc 161, a second disc 162 and a third disc 163 arranged in sequence. The first conductive part and the second conductive part are arranged on two of the first disc 161, the second disc 162 and the third disc 163 respectively, for example, when the first conductive part is arranged on the second disc 162 and the second conductive part is arranged on the third disc 163, the second disc 162 and the third disc 163 are connected through the insulating connecting part 130; when the first conductive part is arranged on the first disc 161 and the second conductive part is arranged on the third disc 163, the second disc 162 can be regarded as a part of the insulating connecting part 130, which can be arranged as an insulating material or an electrically conductive material.

[0168] In the embodiment, the first conductive part is the first electrode 116 arranged on the first disc 161, and the second conductive part is the second electrode 123 arranged on the second disc 162. In the embodiment, the first disc 161 is used for anchoring in the left atrial appendage, the third disc 163 is used for occluding the left atrial appendage opening, and the second disc 162 is located near the left atrial appendage opening.

[0169] It should be noted that the specific technical solutions in the above embodiments of the present application can be mutually applicable.

[0170] The above is only a specific implementation of the present application, but the protection scope of the present application is not limited to this. Any changes or replacements within the technical range disclosed in the present application can be easily thought by those skilled in the art, which should be covered in the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.

Claims

1. A left atrial appendage occlusion ablation device, characterized by, The application relates to an ablation device, which comprises: an anchor disc, a sealing disc, and an insulating connecting piece. The anchor disc comprises a first skeleton, the distal end of the first skeleton is provided with an opening, and the anchor disc is provided with a first conductive part. The sealing disc is provided with a second conductive part. The insulating connecting piece is connected with the anchor disc and the sealing disc at two ends respectively. The first conductive part and the second conductive part are used for transmitting ablation energy to tissues. The insulating connecting piece is provided with a first conductive connecting part, the first conductive connecting part is used for detachably connecting with a conductive cable in a delivery device, and the conductive cable is electrically connected with the first conductive part through the first conductive connecting part. The sealing disc comprises a second skeleton and a second conductive connecting part, the proximal end of the second skeleton is connected with the second conductive connecting part, the second conductive connecting part is used for detachably connecting with a catheter in a delivery device, and an external signal source is electrically connected with the second conductive part through the catheter and the second conductive connecting part in sequence. The insulating connecting piece is provided with a through hole in the axial direction to form a cavity, the first conductive connecting part is arranged on the inner surface of the insulating connecting piece, the insulating connecting piece is provided with a first mounting space, the first mounting space is annular, and one end of the anchor disc is collected in the first mounting space. The first conductive connecting part is connected with the conductive cable through thread connection, magnetic connection or clamping.

2. The left atrial appendage occlusion ablation device of claim 1, wherein, The insulating connecting piece comprises a first connecting piece and at least one second connecting piece which are connected in sequence, the anchor disc is connected with the first connecting piece, the first connecting piece comprises the first conductive connecting part, the distal end of the sealing disc is connected with one of the second connecting pieces, at least one of the second connecting pieces is in a cylindrical shape and is provided with a channel for the conductive cable to pass through, and the first conductive connecting part is insulatively connected with at least one of the second connecting pieces.

3. The left atrial appendage occlusion ablation device of claim 1, wherein, At least part of the axial section of the first connecting piece near the first conductive connecting part is insulated; and / or 4. The left atrial appendage occlusion ablation device of claim 3, wherein, At least part of the axial section of at least one of the second connecting pieces is insulated. The insulating connecting piece further comprises a third connecting piece, the distal end of the sealing disc is collected in the third connecting piece, the distal end of the third connecting piece is connected with the proximal end of one of the second connecting pieces, and the first conductive connecting part is insulatively connected with the third connecting piece.

5. The left atrial appendage occlusion ablation device of claim 3, wherein, At least part of the axial section of the first connecting piece near the first conductive connecting part is insulated; and / or 6. The left atrial appendage occlusion ablation device of claim 5, wherein, At least part of the axial section of at least one of the second connecting pieces is insulated; and / or At least part of the axial section of the third connecting piece is insulated. The first connecting piece is in a cylindrical shape, the outer surface of the first connecting piece is insulated, and the inner surface of the first connecting piece is provided with the first conductive connecting part.

7. The left atrial appendage occlusion ablation device of claim 3, wherein, The first connecting piece or one of the second connecting pieces is provided with a first mounting space; and / or 8. The left atrial appendage occlusion ablation device of claim 5, wherein, The third connecting piece is provided with a second mounting space, and the distal end of the sealing disc is collected in the second mounting space. One end of the anchor disc is collected in one of the second connecting pieces, and at least the surface of the second connecting piece in which the anchor disc is collected is insulated.

9. The left atrial appendage occlusion ablation device of claim 3, wherein, ​ 10. The left atrial appendage occlusion ablation device of claim 3, wherein, The at least one second connector is three second connectors, one of which is conductive, and the other two are insulated, the conductive second connector is connected between the two insulated second connectors, and one end of the anchor disc is narrowed to the conductive second connector.

11. The left atrial appendage occlusion ablation device of claim 1, wherein, The insulated connector is provided with a through cavity for the conductive cable, and the through cavity extends to the first conductive connection part.

12. The left atrial appendage occlusion and ablation device of any of claims 1-11, wherein, The parts connected to each other in the insulated connector are detachably connected.

13. The left atrial appendage occlusion ablation device of any of claims 1-11, wherein, The parts connected to each other in the insulated connector are threadedly connected, clamped, interference fit, pivoted or flexibly connected.

14. The left atrial appendage occlusion ablation device of claim 1, wherein, The sealing disc comprises a proximal end portion of the support framework, the anchor disc comprises a distal end portion of the support framework, the first conductive part and the second conductive part are part of the support framework, or are electrode parts provided on the support framework.

15. The left atrial appendage occlusion ablation device of claim 14, wherein, The area corresponding to the first conductive part and the second conductive part in the support framework is an active area, and the area outside the active area in the support framework is an insulating area. At least part of the support framework in the insulating area is made of insulating material; or The inner side and the outer side surface of at least part of the support framework corresponding to the insulating area are covered by an insulating film.

16. The left atrial appendage occlusion ablation device of claim 1, wherein, The first conductive part and / or the second conductive part extend along the circumferential bending of the left atrial appendage occlusion and ablation device.

17. The left atrial appendage occlusion ablation device of claim 1, wherein, The sealing disc comprises a second framework and a flow blocking film provided on the second framework, and the flow blocking film is used to block the thrombus at the distal end of the flow blocking film from moving proximally.

18. The left atrial appendage occlusion ablation device of claim 1, wherein, The anchor disc comprises a plurality of support parts and a plurality of anchor parts, and the plurality of anchor parts are arranged around the outer periphery of the plurality of support parts; Each support part comprises a support rod and a first branch and a second branch; each support rod has opposite first and second ends, the first ends of the plurality of support rods are connected to the insulated connector, the second ends of the plurality of support rods radially diverge outward, and the first branch and the second branch are connected to the corresponding first end; the end of each first branch away from the support rod is connected to the end of the second branch of the adjacent support part away from the support rod, and the connection forms a first connection point; each anchor part is connected to the corresponding first connection point and extends towards the proximal end.

19. The left atrial appendage occlusion ablation device of claim 18, wherein, The plurality of anchor parts are divided into groups, each group of anchor parts comprises two adjacent anchor parts; the proximal ends of the two anchor parts in each group of anchor parts are connected.

20. The left atrial appendage occlusion ablation device of claim 1, wherein, The sealing disc comprises a second framework, and the first framework and the second framework are made of wire knitting or pipe cutting.

21. The left atrial appendage occlusion ablation device of claim 20, wherein, The distal ends of the first framework are connected together radially inwardly.

22. A left atrial appendage occlusion ablation system, comprising: The left atrial appendage occlusion and ablation system comprises a delivery device and the left atrial appendage occlusion and ablation device of any one of claims 1-21, and the delivery device is used to deliver and release the left atrial appendage occlusion and ablation device.

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