A sterile culture device for preparing influenza vaccine

By designing a sterile culture device including the cabin shell, main control frame, air control component and power component, the problem of constant temperature environment in the existing technology is solved, the precise delivery of vessel bottles and the automatic control of temperature in the cabin are realized, and the level of automation and intelligence of the cultivation process is improved.

CN115537337BActive Publication Date: 2025-04-08AB&B BIO TECH CO LTD JS
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Patent Information

Application Number
CN202211338331.7
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Priority Date
2022-06-16
Filing Date
2022-10-28
Publication Date
2025-04-08
Estimated Expiration
2042-10-28

AI Technical Summary

Technical Problem

During the sterile culture process for the preparation of existing influenza vaccines, it is necessary to frequently open the cabin door to remove the Petri dish or eggs, which will affect the constant temperature environment and poor automation control effect.

Method used

A sterile culture device for the preparation of influenza vaccine was designed, including the cabin shell, main control frame, air control assembly and power assembly. Through the cooperation of the conveyor belt, air control assembly and power assembly, the precise delivery of the vessel bottle and the automatic control of the temperature in the cabin are achieved.

Benefits of technology

It realizes efficient and precise delivery of vessel bottles and stable control of temperature in the square cabin, improves the automation and intelligence level of the entire cultivation process, and reduces interference to the constant temperature environment.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention relates to the field of vaccine culture technology, and specifically to an aseptic culture device for preparing influenza vaccine, comprising a cabin shell, in which a plurality of evenly distributed main control frames are arranged, the main control frames comprising a conveyor belt, an air control component, a power component, a slide rail and a door component, and a plurality of evenly distributed air control components are arranged above the conveyor belt. The structural design of the present invention realizes the process of sending a vessel bottle to the outside of the cabin, and only needs to control the solenoid valve above it to open, and at the same time supply a temperature airflow to a collecting and distributing pipe, so as to trigger the transmission control of the air control component and the power component. The air control component and the power component cooperate to achieve the effect of highly automated control, so that the designated vessel bottle is accurately transported to the outside of the cabin shell, and the temperature inside the cabin shell is effectively controlled during the process, so as to ensure the stability of the constant temperature culture environment inside the cabin shell.
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Description

Technical Field

[0001] The invention relates to the technical field of vaccine culture, in particular to a sterile culture device for preparing influenza vaccine. Background Art

[0002] In the aseptic culture process for influenza vaccine preparation in the prior art, a large number of culture temperature-controlled cabins are placed in the sterile room to store a large number of culture dishes or culture eggs. Vaccines are injected into the culture dishes or culture eggs for vaccine culture. The temperature in the cabin needs to be controlled to ensure the safe growth of bacteria. The staff needs to take out the culture dishes or eggs regularly for observation and treatment, which will affect the constant temperature environment in the cabin. For this reason, we provide a constant temperature compensation mechanism for the aseptic culture system. After the cabin door is opened, the heat in the cabin overflows. The constant temperature compensation mechanism continuously injects heated air into the cabin during the cabin door opening stage to ensure the internal temperature of the cabin without affecting other bacteria cultured in the cabin. In addition, the temperature compensation mechanism in the cabin is connected with the precise conveying mechanism for the culture dishes. It only needs to supply air to the temperature compensation mechanism, and at the same time, the solenoid valve at the designated position is opened through the system main control terminal, which triggers a series of automated work in the cabin, thereby improving the intelligent automation control effect of the entire culture cabin. Summary of the invention

[0003] The object of the present invention is to provide a sterile culture device for preparing influenza vaccines to solve the problems raised in the above background technology.

[0004] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: an aseptic culture device for preparing influenza vaccine, comprising a cabin shell, a plurality of evenly distributed main control frames are arranged in the cabin shell, the main control frames include a conveyor belt, an air control component, a power component, a slide rail and a door component, a plurality of evenly distributed air control components are arranged above the conveyor belt, a power component is arranged at one end of the air control component, a slide rail is distributed in parallel on one side of the conveyor belt, the slide rail is connected to the air control component in a transmission manner, the conveyor belt and the slide rail both partially extend to the outside of the cabin shell, a plurality of evenly distributed square holes are opened on one side of the cabin shell, the door assembly is blocked at the square hole of the cabin shell, the slide rail includes an intercepting plate, an L-shaped short plate, a tension spring, a brake plate, a control rail column and a brake long plate, a T-shaped columnar control rail column is distributed in parallel on one side of the brake long plate, and the control rail column is arranged in a T-shaped slide groove opened on the brake long plate.

[0005] Preferably, one end of the control rail column extends to the outside of the braking long plate, and an intercepting plate is fixedly connected to the end of the control rail column, an L-shaped short plate is fixed to the braking long plate on one side of the intercepting plate, a tension spring is fixedly connected to one side of the intercepting plate, one end of the tension spring is fixedly connected to the braking plate, the braking plate is fixed on the braking long plate, and a plurality of evenly distributed protruding teeth are provided on one side wall of the braking long plate.

[0006] Preferably, the door assembly includes a switch door, a bolt rod, a pressure plate and a concave plate frame, the switch door is sealed at the square hole on the cabin shell, one end of the switch door is fixedly connected to the pressure plate, one end of the bolt rod is pressed against the pressure plate, the other end of the bolt rod contacts the L-shaped short plate, the concave plate frame is fixed on the inner wall of the cabin shell, the bolt rod passes through the inner cavity of the concave plate frame, and part of the bolt rod is movably sleeved in the through hole opened on the cabin shell.

[0007] Preferably, the air control assembly includes a riser, an air column, a cutoff block, a sleeve, an L-shaped control plate, a first spring, a container bottle, a lifting plate rack, a loading plate and an L-shaped air pipe, the upper end of the riser extends to the outside of the cabin shell, the lower end of the riser is movably sleeved with an air column, one side of the riser is connected to an L-shaped air pipe, one end of the L-shaped air pipe extends into the power assembly, the air column is sleeved with a sleeve and a first spring, the sleeve is fixedly sleeved on the air column, the upper end of the first spring contacts the sleeve, the lower end of the first spring contacts the L-shaped control plate, one side of the air column is fixedly connected to the cutoff block, the cutoff block is arranged in a long plate hole opened on the L-shaped control plate, and the air column passes through the plate body of the L-shaped control plate.

[0008] Preferably, the bottom end of the gas column is fixedly connected to a lifting plate frame, and the lifting plate frame is shaped like two parallel L-shaped plates with a vertical plate integrally connected therebetween. A loading plate is supported on the lifting plate frame, and the loading plate is in the shape of a T-shaped plate, and a circular plate groove is provided on the loading plate body, and the vessel bottle is placed in the circular plate groove of the loading plate.

[0009] Preferably, the power assembly includes a boost cylinder, an L-shaped support rod, fan blades, an external frame, a cylinder gear, a support block, a transverse axis, a second spring, an L-shaped intercepting plate, an internal plate, an internal control column, an air guide tube and an air box, one side of the L-shaped intercepting plate is in sliding contact with a support block, a transverse axis passes through the support block, one end of the transverse axis is fixedly sleeved with a cylinder gear, and the other end of the transverse axis is fixedly sleeved with fan blades, the fan blades are shaped like a plurality of evenly distributed square plates arranged on the outer wall of the cylinder, the cylinder gear is transmission-connected to a brake long plate below, the brake long plate is located directly below the cylinder gear, and the brake long plate falls down and meshes with the cylinder gear.

[0010] Preferably, a trapezoidal booster cylinder is provided above the fan blades, and an air box is provided below the fan blades. The booster cylinder is in the shape of a funnel shell, and an L-shaped air pipe is provided above the booster cylinder. The bottom end of the L-shaped air pipe extends into the booster cylinder, and an L-shaped support rod is fixedly connected between the booster cylinder and the support block.

[0011] Preferably, the lower part of the support block is fixedly connected to an inner control column, a second spring is sleeved on the inner control column, the second spring pad is placed between the support block and the L-shaped intercepting plate, the inner control column is movably sleeved in a through hole opened on the bottom plate of the L-shaped intercepting plate, one side of the bottom of the vertical plate of the L-shaped intercepting plate is fixedly connected to a U-shaped inner connecting plate, one end of the inner connecting plate is fixed on the L-shaped intercepting plate, the other end of the inner connecting plate is fixed on the air box, the air box is a square box shell with an opening on the top, one side of the top of the vertical plate of the L-shaped intercepting plate is fixedly connected to an external frame, one end of the external frame is fixedly connected to a control rail column, a portion of the control rail column protrudes to the outside of the brake long plate, and the external frame is fixed to the protruding portion of the control rail column.

[0012] Preferably, the air box is in the shape of a box shell with an opening on the top, one side of the air box is connected to an air duct, part of the tube body of the air duct is distributed parallel to the conveyor belt, and a plurality of evenly distributed through holes are opened on the part of the tube body.

[0013] Compared with the prior art, the present invention has the following beneficial effects:

[0014] 1. The structural design of the present invention realizes the process of delivering the container bottle to the outside of the shelter. It only needs to control the solenoid valve above it to open, and supply the temperature airflow to the distribution pipe at the same time, which can trigger the transmission control of the air control component and the power component. The air control component and the power component cooperate to achieve the effect of highly automated control, so that the designated container bottle is accurately delivered to the outside of the shelter shell, and the temperature inside the shelter shell is effectively controlled during the process, ensuring the stability of the constant temperature culture environment inside the shelter shell;

[0015] 2. The present invention realizes effective control and guidance of the kinetic energy of the airflow by setting a series of sophisticated transmission parts in the air control component and the power component, thereby realizing the effect of automatic control. After the detection and processing work is completed, the air supply of the distribution pipe is controlled, and the terminal signal of the solenoid valve is controlled. The air control component and the power component can be reset and controlled stably, and the vessel bottle can be automatically stored back to the designated position in the cabin. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the structure of the present invention.

[0017] Figure 2 This is a schematic diagram of the main control frame structure.

[0018] Figure 3 It is a schematic diagram of the slide rail structure.

[0019] Figure 4 Schematic diagram of the conveyor belt structure.

[0020] Figure 5 Schematic diagram of the door assembly structure.

[0021] Figure 6 This is a schematic diagram of the gas control component structure.

[0022] Figure 7 This is a schematic diagram of the power component structure.

[0023] Figure 8 Schematic diagram of the airway structure.

[0024] Fig. 9 Schematic diagram of the gas box structure.

[0025] Fig.10 It is a schematic diagram of the brake long board structure.

[0026] Fig.11 This is the L-shaped trachea location distribution map.

[0027] Fig.12 for Fig.11 Schematic diagram of the structure at point A in the middle.

[0028] In the figure: cabin shell 1, main control frame 2, conveyor belt 3, air control assembly 4, power assembly 5, slide rail 6, door assembly 7, solenoid valve 8, collecting and distributing pipe 9, interception plate 10, L-shaped short plate 11, tension spring 12, brake plate 13, control rail column 14, brake long plate 15, switch door 16, bolt rod 17, pressure plate 18, concave plate frame 19, riser 20, gas column 22, cut-off block 23, sleeve 24, L-shaped control plate 25, first spring 26, vessel bottle 27, lifting plate frame 28, loading plate 29, L-shaped air pipe 30, booster cylinder 31, L-shaped support rod 32, fan blade 33, external frame 34, cylinder gear 35, support block 36, horizontal axis 37, second spring 38, L-shaped interception plate 39, internal plate 40, internal control column 41, air guide pipe 42, air box 43. DETAILED DESCRIPTION

[0029] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the technical solutions in the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0030] See also Figures 1 to 12The present invention provides a technical solution: a sterile culture device for preparing influenza vaccine, comprising a cabin shell 1, a plurality of evenly distributed main control frames 2 are arranged in the cabin shell 1, the main control frame 2 comprises a conveyor belt 3, an air control component 4, a power component 5, a slide rail 6 and a door component 7, a plurality of evenly distributed air control components 4 are arranged above the conveyor belt 3, a power component 5 is arranged at one end of the air control component 4, a slide rail 6 is distributed in parallel on one side of the conveyor belt 3, and the slide rail 6 and the air control component 4 are transmission-connected The conveyor belt 3 and the slide rail member 6 are partially extended to the outside of the cabin shell 1. A plurality of evenly distributed square holes are opened on one side of the cabin shell 1. The door assembly 7 is blocked at the square holes of the cabin shell 1. The slide rail member 6 includes an intercepting plate 10, an L-shaped short plate 11, a tension spring 12, a brake plate 13, a control rail column 14 and a brake long plate 15. A T-shaped columnar control rail column 14 is distributed in parallel on one side of the brake long plate 15. The control rail column 14 is set in a T-shaped slide groove opened on the brake long plate 15.

[0031] One end of the control rail post 14 extends to the outside of the brake long plate 15, and the end of the control rail post 14 is fixedly connected to the interception plate 10, and the brake long plate 15 on one side of the interception plate 10 is fixedly connected to an L-shaped short plate 11, and one side of the interception plate 10 is fixedly connected to a tension spring 12, and one end of the tension spring 12 is fixedly connected to a brake plate 13, and the brake plate 13 is fixed on the brake long plate 15. A plurality of evenly distributed protruding teeth are arranged on one side wall of the brake long plate 15, refer to Figure 4 It is understood that the conveyor belt 3 is a conveyor belt mechanism in the prior art, and a gear structure is set on a driving shaft at one end of the conveyor belt. The gear structure and the brake long plate 15 are meshed and driven to connect, and the movement of the brake long plate 15 drives the conveyor belt, thereby realizing the movement of the vessel bottle 7 falling thereon.

[0032] The door assembly 7 includes a switch door 16, a bolt rod 17, a pressure plate 18 and a concave plate frame 19. The switch door 16 is blocked at the square hole on the cabin shell 1. One end of the switch door 16 is fixedly connected to the pressure plate 18. One end of the bolt rod 17 is pressed against the pressure plate 18. The other end of the bolt rod 17 contacts the L-shaped short plate 11. Here, the L-shaped short plate 11 is telescopically arranged on the brake long plate 15 through an electric push rod. The electric push rod is arranged in the brake long plate 15 to control the telescopic movement of the L-shaped short plate 11. The purpose of the telescopic movement is to achieve the switching between limited and unlimited positions. The concave plate frame 19 is fixed on the inner wall of the cabin shell 1. The bolt rod 17 passes through the inner cavity of the concave plate frame 19. Part of the bolt rod 17 is movably sleeved in the through hole opened on the cabin shell 1. Fig.12It is understood that the switch door 16 is an up and down flip revolving door controlled by a torsion spring in the prior art, a torsion spring is sleeved on the door shaft, one end of the torsion spring is fixed on the shell of the cabin shell 1, the torsion spring applies continuous elastic force to the door, a pressure plate 18 fixedly connected to one end of the door shaft is supported by the bolt rod 17, if the bolt rod 17 is retracted into the cabin shell 1, the door shaft, which is only subjected to the pressure of the torsion spring, rotates, the door panel flips upward, and the discharge square hole on the cabin shell 1 is exposed, and the bolt rod 17 is retracted into the cabin shell 1 because the L-shaped short plate 11 moves and no longer supports the bottom end of the bolt rod 17.

[0033] The air control assembly 4 includes a riser 20, an air column 22, a stop block 23, a sleeve 24, an L-shaped control plate 25, a first spring 26, a container bottle 27, a lifting plate frame 28, a loading plate 29 and an L-shaped air pipe 30. The upper end of the riser 20 extends to the outside of the cabin shell 1, and the lower end of the riser 20 is movably sleeved with the air column 22. One side of the riser 20 is connected to the L-shaped air pipe 30, and one end of the L-shaped air pipe 30 extends to the power assembly 5. The air column 22 is sleeved with a sleeve 24 and a first spring 26. The sleeve 24 is fixedly sleeved on the air column 22. The upper end of the first spring 26 contacts the sleeve 24, and the lower end of the first spring 26 contacts the L-shaped control plate 25. One side of the air column 22 is fixedly connected to the stop block 23. The stop block 23 is set in a long plate hole opened on the L-shaped control plate 25. The air column 22 passes through the plate body of the L-shaped control plate 25. Figure 2 and Figure 6 It is understood that the top of the riser 20 is connected with the solenoid valve 8 in the prior art, the collecting and distributing pipe 9 is connected with multiple solenoid valves 8, one end of the collecting and distributing pipe 9 is connected with the hot air flow supply mechanism in the prior art, and a mature heating air pump can be selected to carry out the air supply process in the cabin shell 1, control the control terminal of the culture system, control the designated solenoid valve 8 and the heating air pump to make the top of the corresponding riser 20 unobstructed, so that the hot air flow injected into the collecting and distributing pipe 9 is then injected into the riser 20, thereby triggering the control of the air control component 4 and the power component 5.

[0034] The bottom end of the gas column 22 is fixedly connected with a lifting plate frame 28, which is shaped like two parallel L-shaped plates with a vertical plate integrally connected therebetween. A loading plate 29 is supported on the lifting plate frame 28, and the loading plate 29 is in the shape of a T-shaped plate, and a circular plate groove is provided on the loading plate 29, in which the container bottle 27 is placed.

[0035] The power assembly 5 includes a boost cylinder 31, an L-shaped support rod 32, a fan blade 33, an external frame 34, a cylinder gear 35, a support block 36, a transverse axis 37, a second spring 38, an L-shaped intercepting plate 39, an internal plate 40, an internal control column 41, an air guide tube 42 and an air box 43. One side of the L-shaped intercepting plate 39 is in sliding contact with the support block 36, and a transverse axis 37 runs through the support block 36. One end of the transverse axis 37 is fixedly sleeved with a cylinder gear 35, and the other end of the transverse axis 37 is fixedly sleeved with a fan blade 33. The fan blade 33 is shaped like a plurality of evenly distributed square plates arranged on the outer wall of the cylinder. The cylinder gear 35 is connected to the brake long plate 15 for transmission below, and the brake long plate 15 is located directly below the cylinder gear 35. The second spring 38 contracts the cylinder gear 35 to ensure that the brake long plate 15 and the cylinder gear 35 can be meshed and connected.

[0036] A trapezoidal booster cylinder 31 is arranged above the fan blade 33, and an air box 43 is arranged below the fan blade 33. The booster cylinder 31 is in the shape of a funnel shell. An L-shaped air pipe 30 is arranged above the booster cylinder 31. The bottom end of the L-shaped air pipe 30 extends into the booster cylinder 31. An L-shaped support rod 32 is fixedly connected between the booster cylinder 31 and the support block 36. Fig.11 It is understood that the inner diameter of the closing end of the boost cylinder 31 is smaller than the air outlet of the L-shaped air pipe 30, so that the airflow ejected from the L-shaped air pipe 30 impacts the boost cylinder 31, forcing the boost cylinder 31 to keep the cylinder gear 35 better engaged with the brake long plate 15, while providing a more stable blowing force for the fan blades 33.

[0037] An inner control column 41 is fixedly connected to the bottom of the support block 36, and a second spring 38 is sleeved on the inner control column 41. The second spring 38 is padded between the support block 36 and the L-shaped intercepting plate 39. The inner control column 41 is movably sleeved in a through hole opened on the bottom plate of the L-shaped intercepting plate 39. A U-shaped inner plate 40 is fixedly connected to the bottom side of the vertical plate of the L-shaped intercepting plate 39. One end of the inner plate 40 is fixed on the L-shaped intercepting plate 39, and the other end of the inner plate 40 is fixed on the air box 43. The air box 43 is a square box shell with an open top. An external frame 34 is fixedly connected to the top side of the vertical plate of the L-shaped intercepting plate 39, and one end of the external frame 34 is fixedly connected to the control rail column 14. The control rail column 14 partially protrudes to the outside of the brake long plate 15, and the external frame 34 is fixed on the protruding part of the control rail column 14.

[0038] The air box 43 is in the shape of a box shell with an open top. One side of the air box 43 is connected to the air guide pipe 42. Part of the air guide pipe 42 is parallel to the conveyor belt 3, and a plurality of evenly distributed through holes are opened on the part of the air guide pipe. Figure 8 It is understood that the positions of the plurality of air ducts 42 are distributed so that the hot air discharged from the air ducts 42 can be diffused in the cabin shell 1 .

[0039] When the cabin is working normally, a stable hot air flow is originally supplied to the collecting and distributing pipe 9 to control the opening of the corresponding solenoid valve 8, and the air pressure in the riser 20 is maintained so that the air column 22 can move down to the position where the L-shaped air pipe 30 is connected to the riser 22. At this time, the hot air flow provides a guarantee for the culture temperature in the cabin. When it is necessary to check or inject nutrients into the vessel bottle 27 at the designated position, the solenoid valve increases the air pressure of the hot air flow. The air supply here can use a known heating air pump. Because it is a prior art, the power of the air pump, the size of the air supply pressure and the control of the air valve are all known and there is no difficulty. The increased hot air flow will continue to push the air column 22 downward. During the downward extension process of the air column 22, it continues to overcome the elastic pushing effect of the first spring 26. The air column 22 drives the lifting plate frame 28, and the lifting plate frame 28 controls the loading plate 29 to fall. When the loading plate 29 falls onto the conveyor belt 3, the lifting plate frame 28 continues to fall, and the loading plate 29 and the lifting plate frame 28 are separated. At this time, the loading plate 29 lifts The lifting plate frame 28 falls completely on the conveyor belt 3. At this time, the air column 22 extends downward to the maximum distance, and the increased air flow will be injected into the L-shaped air pipe 30. The hot air flow is ejected from the L-shaped air pipe 30 and impacts the boost cylinder 31. The boost cylinder 31 is to make the cylinder gear 35 and the brake long plate 15 mesh more stably and provide pneumatic action on the fan blade 33. The hot air flow ejected from the boost cylinder 31 impacts the fan blade 33 to control the rotation of the fan blade 33. A part of it will be affected by the fan blade 33. This part of the hot air flow impacts the fan blade 33. The heat is hit into the air box 43, and then diffused above the conveyor belt 3 after being guided by the air guide pipe 42, so as to assist in heating the internal space of the cabin shell 1 (it can offset and reduce the influence of heat loss after the door is opened). The fan blade 33 rotates to drive the horizontal shaft 37, and then controls the rotation of the cylinder gear 35. The cylinder gear 35 drives the brake long plate 15, and the brake long plate 15 slides under the directional guidance of the control rail column 14. The brake long plate 15 drives the driving shaft on the conveyor belt 3, and the conveyor belt 3 works to transport the loading plate 29 that falls thereon.

[0040] The brake long plate 15 moves away from the intercepting plate 10, and the tension spring 12 elastically pulls the brake long plate 15 to realize the later reset of the brake long plate 15. The movement of the brake long plate 15 drives the L-shaped short plate 11, and the electric push rod realizes the telescopic adjustment of the L-shaped short plate 11 in a direction parallel to the axial direction of the horizontal axis 37. That is, when the L-shaped short plate 11 reaches the corresponding power assembly 5, if the telescopic position of the L-shaped short plate 11 is blocked by the horizontal axis 37, the brake long plate 15 stops here. When you want to move to the position of the next power assembly 5, the electric push rod controls the L-shaped short plate 11 to telescope around the first power assembly 5 and go to the next power assembly. Component 5, and so on, the adjustment of the L-shaped short board 11 is achieved through the control of the electric push rod, and the interception is achieved by cooperating with the horizontal axis 37 at the corresponding position. The electric push rod controls the extension and retraction, which is a very simple technology. It can be understood in combination with the drawings of the present application. When the L-shaped short board 11 moves initially, the L-shaped short board 11 no longer supports the bolt rod 17, and directly triggers the flipping and opening of the switch door 16. The loading plate 29 corresponding to the position of the corresponding power component 5 moves with the vessel bottle 27 to the end position of the conveyor belt 3 outside the cabin shell 1, so that the staff can process the culture medium in the removed vessel bottle 27.

[0041] Because the top of the L-shaped short board 11 will eventually be intercepted by the horizontal axis 37 during the movement of the L-shaped short board 11 with the braking long board 15, and the L-shaped short board 11 and the horizontal axis 37 are in a blocking state. At this time, the L-shaped short board 11 reversely controls the braking long board 15, and the braking long board 15 will not continue to move. At this time, the conveyor belt 3 stops after conveying a specified distance, because the tension of the tension spring 12 is stable at this time, and the air pressure at this time controls the rotation of the corresponding control blade 33. The rotational force given by the blade 33 to the cylinder gear 35 is balanced with the tension provided by the tension spring 12, so that the brake long plate 15 can be kept in a stable static state, that is, the conveyor belt 3 is in a conveying static state; when the staff can complete the processing of the removed vessel bottle 27 (that is, the cultured ones are taken away and the new ones to be cultured are put in), the supplied air pressure can be adjusted to weaken, so that the rotational force provided by the cylinder gear 35 is less than the tension of the tension spring 12, and the contraction force of the tension spring 12 is greater than the limiting force that can be provided by the air pressure, the brake long plate 15 is recovered, the conveyor belt is reversed, and the cultured ones enter the cabin again, the door assembly is closed, and the previous culture state is returned. The device is provided with multiple groups of power components 5, corresponding multiple groups of air control components 4, solenoid valves 8, and distribution pipes 9. An air supply heat pump can be set corresponding to one group of the above structure per week, or several groups can share one. The formed culture device can culture multiple groups of vaccines and is a large-scale vaccine culture device that can be industrialized.

[0042] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A sterile culture device for preparing influenza vaccine, comprising a cabin housing (1), characterized in that: The cabin shell (1) is provided with a plurality of evenly distributed main control frames (2), the main control frames (2) comprising a conveyor belt (3), an air control assembly (4), a power assembly (5), a slide rail member (6) and a door assembly (7), a plurality of evenly distributed air control assemblies (4) are provided above the conveyor belt (3), a power assembly (5) is provided at one end of the air control assembly (4), a slide rail member (6) is distributed parallel to one side of the conveyor belt (3), the slide rail member (6) and the air control assembly (4) are transmission-connected, and the conveyor belt (3) and the slide rail member (6) are partially The sliding rail member (6) extends to the outside of the cabin shell (1); a plurality of evenly distributed square holes are opened on one side of the cabin shell (1); a door assembly (7) is sealed at the square holes of the cabin shell (1); the sliding rail member (6) comprises an intercepting plate (10), an L-shaped short plate (11), a tension spring (12), a braking plate (13), a control rail post (14) and a braking long plate (15); a T-shaped columnar control rail post (14) is parallelly distributed on one side of the braking long plate (15); and the control rail post (14) is arranged in a T-shaped slide groove opened on the braking long plate (15); The power assembly (5) comprises a boost cylinder (31), an L-shaped support rod (32), a fan blade (33), an external frame (34), a cylinder gear (35), a support block (36), a transverse shaft (37), a second spring (38), an L-shaped intercepting plate (39), an internal plate (40), an internal control column (41), an air guide tube (42) and an air box (43); one side of the L-shaped intercepting plate (39) is in sliding contact with the support block (36); a transverse shaft (37) runs through the support block (36); one end of the transverse shaft (37) is fixedly sleeved with a cylinder gear (35); the other end of the transverse shaft (37) is fixedly sleeved with a fan blade (33); the fan blade (33) is in the shape of a plurality of evenly distributed square plates arranged on the outer wall of a cylinder; the cylinder gear (35) is transmission-connected to a brake long plate (15) below; the brake long plate (15) is located directly below the cylinder gear (35); and the brake long plate (15) is meshingly connected with the cylinder gear (35); One end of the control rail post (14) extends to the outside of the braking long plate (15), and the end of the control rail post (14) is fixedly connected to an intercepting plate (10), an L-shaped short plate (11) is fixed to the braking long plate (15) on one side of the intercepting plate (10), a tension spring (12) is fixedly connected to one side of the intercepting plate (10), one end of the tension spring (12) is fixedly connected to a braking plate (13), the braking plate (13) is fixed to the braking long plate (15), and a plurality of evenly distributed protruding teeth are provided on one side wall of the braking long plate (15); The door assembly (7) comprises a switch door (16), a bolt rod (17), a pressure plate (18) and a concave plate frame (19); the switch door (16) is sealed at a square hole on the cabin shell (1); one end of the switch door (16) is fixedly connected to the pressure plate (18); one end of the bolt rod (17) is pressed against the pressure plate (18); the other end of the bolt rod (17) contacts the L-shaped short plate (11); the concave plate frame (19) is fixed on the inner wall of the cabin shell (1); the bolt rod (17) passes through the inner cavity of the concave plate frame (19); and part of the bolt rod (17) is movably sleeved in a through hole opened on the cabin shell (1); The air control assembly (4) comprises a standpipe (20), an air column (22), a stop block (23), a sleeve (24), an L-shaped direction control plate (25), a first spring (26), a container bottle (27), a lifting plate frame (28), a loading plate (29) and an L-shaped air pipe (30); the upper end of the standpipe (20) extends to the outside of the cabin shell (1); the lower end of the standpipe (20) is movably sleeved with the air column (22); one side of the standpipe (20) is connected to the L-shaped air pipe (30); one side of the L-shaped air pipe (30) is The end of the gas column (22) extends into the power assembly (5), the gas column (22) is sleeved with a sleeve (24) and a first spring (26), the sleeve (24) is fixedly sleeved on the gas column (22), the upper end of the first spring (26) contacts the sleeve (24), the lower end of the first spring (26) contacts the L-shaped direction control plate (25), one side of the gas column (22) is fixedly connected to a stop block (23), the stop block (23) is arranged in a long plate hole opened on the L-shaped direction control plate (25), and the gas column (22) passes through the plate body of the L-shaped direction control plate (25); The bottom end of the gas column (22) is fixedly connected to a lifting plate frame (28), the lifting plate frame (28) is in the shape of two parallel L-shaped plates with a vertical plate integrally connected therebetween, a loading plate (29) is supported on the lifting plate frame (28), the loading plate (29) is in the shape of a T-shaped plate, and a circular plate groove is provided on the plate body of the loading plate (29), and a vessel bottle (27) is placed in the circular plate groove of the loading plate (29); A trapezoidal-cylindrical booster cylinder (31) is arranged above the fan blade (33), an air box (43) is arranged below the fan blade (33), the booster cylinder (31) is in the shape of a funnel shell, an L-shaped air pipe (30) is arranged above the booster cylinder (31), the bottom end of the L-shaped air pipe (30) extends into the booster cylinder (31), and an L-shaped support rod (32) is fixedly connected between the booster cylinder (31) and the support block (36).

2. The aseptic culture device for preparing influenza vaccine according to claim 1, characterized in that: The lower part of the support block (36) is fixedly connected to an inner control column (41), a second spring (38) is sleeved on the inner control column (41), the second spring (38) is cushioned between the support block (36) and the L-shaped intercepting plate (39), the inner control column (41) is movably sleeved in a through hole provided on the bottom plate of the L-shaped intercepting plate (39), one side of the bottom of the vertical plate of the L-shaped intercepting plate (39) is fixedly connected to a U-shaped plate-shaped inner connecting plate (40), one end of the inner connecting plate (40) is fixed to the L The inner plate (40) is fixed on the L-shaped intercepting plate (39), and the other end of the inner plate (40) is fixed on the air box (43). The air box (43) is in the shape of a square box shell with an open top. One side of the top of the vertical plate of the L-shaped intercepting plate (39) is fixedly connected to an external frame (34), one end of the external frame (34) is fixedly connected to the control rail column (14), the control rail column (14) partially protrudes to the outside of the brake long plate (15), and the external frame (34) is fixed on the protruding part of the control rail column (14).

3. The aseptic culture device for preparing influenza vaccine according to claim 1, characterized in that: The air box (43) is in the shape of a box shell with an open top, one side of the air box (43) is connected to an air guide pipe (42), a portion of the air guide pipe (42) is distributed in parallel above the conveyor belt (3), and a plurality of evenly distributed through holes are provided on the portion of the pipe.

Citation Information

Patent Citations

  • Sterile culture device for influenza vaccine preparation

    CN114752497A