A cardiac shunt and left atrial pressure monitoring system

Abstract

The present application relates to a cardiac shunt and a left atrial pressure monitoring system. The cardiac shunt includes a stent and a pressure detection device. The stent includes a stent body and a stent fixing portion. The stent body has a channel for redistributing atrial blood flow. The stent fixing portion is arranged at both ends of the channel of the stent body. In the pressure detection device, components in an electric energy receiving circuit and a signal sending circuit are arranged on a flexible circuit board, and the flexible circuit board is fixed on the stent fixing portion and the stent body of the stent. A pressure sensor is respectively connected to the electric energy receiving circuit and the signal sending circuit, and is arranged at one end of the channel of the stent. The left atrial pressure monitoring system includes a transceiver and the cardiac shunt. The present application arranges a pressure sensor on the cardiac shunt, and arranges an electric energy receiving circuit and a signal sending circuit to realize a passive wireless working mode, so as to achieve the purpose of integrated treatment and monitoring.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a cardiac shunt and a left atrial pressure monitoring system. Background Art

[0002] Heart failure, or HF for short, is a disease in which the heart's systolic or diastolic function is impaired, and the heart cannot adequately discharge venous blood back to the heart, resulting in blood congestion in the venous system and inability of the arterial system to be perfused with sufficient blood. Interatrial shunt is a new means of treating heart failure. At the same time, since heart failure is a chronic disease, its monitoring, management and early warning are particularly important. For this, left atrial pressure (LAP) is an important indicator for evaluating cardiac function, which has both sensitivity and specificity, early prediction time and high accuracy.

[0003] However, in the prior art, heart failure treatment and left atrial pressure monitoring are independent and separate from each other, resulting in a problem of being unable to monitor in time after treatment. Summary of the invention

[0004] In response to the above technical problems, the present application provides a cardiac shunt and left atrial pressure monitoring system, in which a pressure sensor is arranged on the cardiac shunt, and an electric energy receiving circuit and a signal sending circuit are arranged to realize a passive wireless working mode, so as to achieve the purpose of integrated treatment and monitoring.

[0005] In order to solve the above technical problems, the present application provides a cardiac shunt, including a bracket and a pressure detection device, wherein the pressure detection device includes a flexible circuit board, an electric energy receiving circuit, a signal sending circuit and a pressure sensor;

[0006] The stent comprises a stent body and a stent fixing part, the stent body has a channel for redistributing atrial blood flow, and the stent fixing part is arranged at both ends of the channel of the stent body;

[0007] The components in the electric energy receiving circuit and the signal sending circuit are arranged on the flexible circuit board, and the flexible circuit board is fixed on the bracket fixing part and the bracket body;

[0008] The pressure sensor is connected to the electric energy receiving circuit and the signal sending circuit respectively, and is arranged at one end of the channel of the bracket.

[0009] Optionally, the flexible circuit board includes a first part, a second part and a third part, and the second part and the third part are arranged at the same side of the first part with an interval; the first part is fixed to the outer wall of one end of the bracket body, the second part is fixed to the bracket fixing part, and the third part extends to one end of the channel of the bracket; components in the electric energy receiving circuit and the signal sending circuit are arranged in the first part and the second part, and the pressure sensor is arranged in the third part.

[0010] Optionally, the bracket fixing portion includes a plurality of extension arms arranged at circumferential intervals along the channel, which are symmetrically arranged and extend toward each other between the extension arms at both ends of the channel, and the second portion of the flexible circuit board is fixed to a side of the extension arm facing the outer wall of the bracket body, and the third portion of the flexible circuit board extends from a gap between adjacent extension arms to one end of the channel of the bracket.

[0011] Optionally, there are two second parts, and the bracket fixing parts arranged at both ends of the bracket body each include six extension arms, and the two second parts are respectively fixed to the two extension arms at the same end of the bracket body.

[0012] Optionally, the first part is fixed around the bracket body.

[0013] Optionally, the electric energy receiving circuit includes a first coupling coil and a power supply circuit, the first coupling coil is used to receive external electric energy, the input end of the power supply circuit is connected to the first coupling coil, and the output end of the power supply circuit is respectively connected to the signal sending circuit and the pressure sensor.

[0014] Optionally, the signal sending circuit includes a microcontroller, a load modulation circuit and a second coupling coil, the microcontroller is connected to the load modulation circuit and the pressure sensor respectively, the input end of the load modulation circuit is connected to the microcontroller, the output end of the load modulation circuit is connected to the second coupling coil, and the second coupling coil is used to send the detection signal of the pressure sensor.

[0015] Optionally, the first coupling coil and the second coupling coil are the same coil.

[0016] Optionally, the first coupling coil and the second coupling coil both include a magnetic sheet and a coil, the coil is arranged in the channel of the bracket and extends axially spirally along the inner wall of the channel, the magnetic sheet is cylindrical and fixed on the inner side of the coil, and both ends of the coil are connected to pins on the flexible circuit board.

[0017] The present application also provides a left atrial pressure monitoring system, comprising a transceiver and a cardiac shunt as described above, wherein the transceiver is wirelessly connected to a pressure detection device of the cardiac shunt, and the transceiver is used to provide electrical energy to an electrical energy receiving circuit of the pressure detection device, and to receive a pressure detection signal sent by a signal sending circuit of the pressure detection device.

[0018] The cardiac shunt and left atrial pressure monitoring system of the present application, the cardiac shunt includes a stent and a pressure detection device, the stent includes a stent body and a stent fixing part, the stent body has a channel for redistributing atrial blood flow, and the stent fixing part is arranged at both ends of the channel of the stent body; in the pressure detection device, the components in the electric energy receiving circuit and the signal sending circuit are arranged on a flexible circuit board, and the flexible circuit board is fixed on the stent fixing part and the stent body of the stent; the pressure sensor is respectively connected to the electric energy receiving circuit and the signal sending circuit, and is arranged at one end of the channel of the stent. The left atrial pressure monitoring system includes a transceiver and the cardiac shunt. The present application arranges a pressure sensor on the cardiac shunt, and arranges an electric energy receiving circuit and a signal sending circuit to realize a passive wireless working mode, so as to achieve the purpose of integrated treatment and monitoring. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 is one of the overall structural schematic diagrams of the cardiac shunt according to the first embodiment;

[0020] Figure 2 is a second schematic diagram of the overall structure of the cardiac shunt according to the first embodiment;

[0021] Figure 3 is along Figure 1 Sectional view along line AA;

[0022] Figure 4 is along Figure 1 Sectional view along the midline BB;

[0023] Figure 5 is a schematic diagram of an unfolded state of a flexible circuit board according to the first embodiment;

[0024] Figure 6 is a cross-sectional view of a flexible circuit board according to a first embodiment;

[0025] Figure 7 is a schematic diagram of the circuit structure of a cardiac shunt according to the first embodiment;

[0026] Figure 8 FIG. 4 is a schematic structural diagram of a pressure detection system according to the second embodiment. DETAILED DESCRIPTION

[0027] The following is an explanation of the implementation of the present application by means of specific embodiments. People familiar with the art can easily understand other advantages and effects of the present application from the contents disclosed in this specification.

[0028] In the following description, reference is made to the accompanying drawings, which describe several embodiments of the present application. It should be understood that other embodiments may be used and that mechanical, structural, electrical, and operational changes may be made without departing from the spirit and scope of the present application. The following detailed description should not be considered limiting, and the terms used herein are only for the purpose of describing specific embodiments and are not intended to limit the present application.

[0029] Although the terms first, second, etc. are used herein to describe various elements in some instances, these elements should not be limited by these terms. These terms are only used to distinguish one element from another element.

[0030] Furthermore, as used in this article, the singular forms "one", "an" and "the" are intended to include plural forms as well, unless there is an indication to the contrary in the context. It should be further understood that the terms "comprise", "include" indicate the presence of the described features, steps, operations, elements, components, projects, kinds, and / or groups, but do not exclude the presence, occurrence or addition of one or more other features, steps, operations, elements, components, projects, kinds, and / or groups. The terms "or" and "and / or" used herein are interpreted as inclusive, or mean any one or any combination. Therefore, "A, B or C" or "A, B and / or C" means "any of the following: A; B; C; A and B; A and C; B and C; A, B and C". Exceptions to this definition will only occur when the combination of elements, functions, steps or operations is inherently mutually exclusive in some way.

[0031] First embodiment

[0032] Please combine Figures 1 to 4 A cardiac shunt of the present application includes a support 10 and a pressure detection device, and the pressure detection device includes a flexible circuit board 20, an electric energy receiving circuit, a signal sending circuit and a pressure sensor 28. The support 10 includes a support body 11 and a support fixing portion 12, the support body 11 has a channel 111 for redistributing atrial blood flow, and the support fixing portion 12 is arranged at both ends of the channel 111 of the support body 11. The flexible circuit board 20 is fixed on the support fixing portion 12 and the support body 11, and the components in the electric energy receiving circuit and the signal sending circuit are arranged on the flexible circuit board 20. The pressure sensor 28 is arranged at one end of the channel 111 of the support 10, and the pressure sensor 28 is connected to the electric energy receiving circuit and the signal sending circuit respectively.

[0033] In the above structure, the circuit components of the pressure detection device are arranged on the bracket 10 using the flexible circuit board 20, so as to achieve the purpose of integrated treatment and monitoring. At the same time, the flexible circuit board 20 is used to integrate flexible electronics, so that the components can be better integrated on the bracket 10, meeting the demand for miniaturization of the device. The electric energy receiving circuit and the signal sending circuit are set to realize the passive wireless working mode, which can meet the demand for long-term operation and reduce the trauma and cost caused by replacing the device.

[0034] Please refer to Figure 1 and Figure 3 The stent 10 is the main structure of the cardiac shunt, which can provide sufficient mechanical strength to support the puncture and hole in the patient's atrial septum. The stent fixing part 12 and the stent body 11 are an integrated structure. The inner wall of the stent body 11 defines a channel 111 for redistributing atrial blood flow, thereby forming a shunt between the left and right atria, reducing the pressure in the left atrium or preventing the pressure in the left atrium from increasing. The stent fixing part 12 is used to position the stent 10 in the puncture and hole in the atrial septum to ensure the position stability of the stent 10.

[0035] Optionally, the bracket fixing portion 12 includes a plurality of extension arms arranged at intervals along the circumference of the channel 111, and the extension arms at both ends of the channel 111 are symmetrically arranged and extend toward each other to achieve a better fixing effect. In this embodiment, the bracket fixing portions 12 arranged at both ends of the bracket body 11 each include six extension arms. It can be understood that the number and arrangement of the extension arms can be adjusted according to the size of the bracket 10, and are not limited thereto.

[0036] The flexible circuit board 20 can use PI (polyimide) material as the base material, which has the characteristics of high wiring density, light weight, thin thickness and good bendability. Figure 5 , which is a schematic diagram of the flexible circuit board 20 in the unfolded state. The flexible circuit board 20 includes a first portion 21, a second portion 22 and a third portion 23. The second portion 22 and the third portion 23 are arranged at intervals on the same side of the first portion 21. When the first portion 21 is wound, the second portion 22 and the third portion 23 can be distributed at different positions in the circumferential direction, so as to better conform to the structural form of the bracket 10, and components can be arranged on the flexible circuit board 20 more conveniently. When installing the flexible circuit board 20, as shown in FIG. Figures 1 to 4As shown, the first part 21 of the flexible circuit board 20 is fixed to the outer wall of one end of the bracket body 11, preferably fixed around the bracket body 11 to obtain better stability; the second part 22 of the flexible circuit board 20 is fixed to the bracket fixing part 12, preferably fixed to the side of the extension arm facing the outer wall of the bracket body 11, so that a smaller size of the flexible circuit board 20 can be designed; the third part 23 extends to one end of the channel 111 of the bracket 10, preferably extending from the gap between adjacent extension arms to one end of the channel 111 of the bracket 10, for installing the pressure sensor 28, at this position, the pressure sensor 28 can more accurately detect the left atrial pressure, while avoiding or reducing the influence of endothelialization at the puncture hole, and extending the service life of the sensor. Optionally, the pressure sensor includes a bare chip and a flexible packaging layer, the bare chip is fixed on the first part of the flexible circuit board, and is electrically connected to the pins on the flexible circuit board through leads, and the flexible packaging layer can cover the bare chip by dispensing glue to meet the waterproof requirements.

[0037] In this embodiment, the components in the electric energy receiving circuit and the signal transmitting circuit are arranged in the first part 21 and the second part 22. Optionally, the second part 22 is used to arrange the main components in the electric energy receiving circuit and the signal transmitting circuit, such as capacitors, resistors, chips, etc. The first part 21 is mainly used for routing to have good flexibility. The number of the second part 22 can be selected according to the number and size of the components. Figure 2 , Figure 4 and Figure 5 In this embodiment, there are two second parts 22, and the two second parts 22 are respectively fixed on two extension arms at the same end of the bracket body 11. Preferably, the positions of the extension arms provided with the second parts 22 are symmetrical to each other.

[0038] Please refer to Figure 6 The packaging structure of the flexible circuit board 20 includes a first insulating layer 201, a biocompatible layer 202, a component layer 203, a flexible substrate 204 and a second insulating layer 205 stacked in sequence. The first insulating layer 201 and the second insulating layer 205 are used to ensure the insulation and water-proof properties of the circuit, and the materials used can be silicone, polyimide, etc., preferably silicone. The component layer 203 is used to arrange circuit components and circuit routing.

[0039] Please refer to Figure 7, is a circuit connection diagram of this embodiment. The electric energy receiving circuit and the signal sending circuit use the same coupling coil 24, wherein the electric energy receiving circuit includes the coupling coil 24 and the power supply circuit 25, and the signal sending circuit includes the microcontroller 27, the load modulation circuit 26 and the coupling coil 24, the coupling coil 24 is used to receive external electric energy and send the detection signal of the pressure sensor 28, the input end of the power supply circuit 25 is connected to the coupling coil 24, the output end of the power supply circuit 25 is respectively connected to the microcontroller 27 and the pressure sensor 28, the microcontroller 27 is respectively connected to the load modulation circuit 26 and the pressure sensor 28, the input end of the load modulation circuit 26 is connected to the microcontroller 27, and the output end of the load modulation circuit 26 is connected to the coupling coil 24. In actual implementation, there can be two coupling coils 24, namely the first coupling coil and the second coupling coil, wherein the first coupling coil is used in the electric energy receiving circuit to receive external electric energy, and the second coupling coil is used in the signal sending circuit to send the detection signal of the pressure sensor 28.

[0040] Specifically, the external electric energy can be coupled to the coupling coil 24 in the pressure detection device in the form of high-frequency electromagnetic energy, and the power supply circuit 25 is used to rectify and stabilize the received high-frequency electric energy and convert it into a working voltage suitable for the microcontroller 27 and the pressure sensor 28. The microcontroller 27 can be a microcontroller unit (MCU), which has low power consumption, thereby reducing the circuit power consumption of the pressure detection device, thereby obtaining a longer transmission distance of electric energy and data.

[0041] The detection signal of the pressure detection device is transmitted to the external device through the coupling coil 24 in a load impedance modulation manner. Specifically, the microcontroller 27 controls the load modulation circuit 26 to change the voltage across the coupling coil 24 according to the detection data of the pressure sensor 28. Based on the inductive coupling between the coupling coil 24 and the coil in the external device, the change in the voltage across the coupling coil 24 will cause the amplitude change of the voltage across the coil in the external device. The change in the voltage amplitude of the coil in the external device can use the principle of envelope detection to realize the demodulation of the low-frequency signal, and further data shaping is performed to read the detection data to realize the transmission of the detection signal.

[0042] Through the above method, the working power of the pressure detection device is provided based on the coupling coil 24, and the pressure detection data is synchronously transmitted to the external device. The structure is simple, and there is no need to set up a power module and a signal transmission line, which can meet the needs of long-term operation.

[0043] Please combine Figure 3 and Figure 4The coupling coil 24 includes a magnetic sheet 242 and a coil 241. The coil 241 is disposed in the channel 111 of the bracket 10 and extends axially and spirally along the inner wall of the channel 111. The magnetic sheet 242 is cylindrical and fixed to the inner side of the coil 241 to ensure the smooth passage of the channel 111 in the bracket 10. Both ends of the coil 241 are connected to the pins on the flexible circuit board 20. Preferably, the magnetic sheet 242 is made of ferrite material, which has the advantages of high magnetic permeability and strong signal gathering ability, and is helpful to receive more electromagnetic energy.

[0044] The cardiac shunt of the present application includes a stent and a pressure detection device. The stent includes a stent body and a stent fixing part. The stent body has a channel for redistributing atrial blood flow. The stent fixing part is arranged at both ends of the channel of the stent body. In the pressure detection device, components in the electric energy receiving circuit and the signal sending circuit are arranged on a flexible circuit board. The flexible circuit board is fixed on the stent fixing part and the stent body of the stent. The pressure sensor is respectively connected to the electric energy receiving circuit and the signal sending circuit, and is arranged at one end of the channel of the stent. The present application arranges a pressure sensor on the cardiac shunt, and arranges an electric energy receiving circuit and a signal sending circuit to realize a passive wireless working mode, so as to achieve the purpose of integrated treatment and monitoring.

[0045] Second embodiment

[0046] The present application also provides a left atrial pressure monitoring system, including a transceiver and a cardiac shunt as described in the first embodiment, the transceiver and the pressure detection device of the cardiac shunt are wirelessly connected, the transceiver is used to provide electrical energy to the electrical energy receiving circuit of the pressure detection device, and to receive the pressure detection signal sent by the signal sending circuit of the pressure detection device.

[0047] like Figure 8 As shown, the connection mode of the circuit part is mainly illustrated. The electric energy receiving circuit of the pressure detection device includes a coupling coil 24 and a power supply circuit 25, and the signal sending circuit includes a microcontroller 27, a load modulation circuit 26 and a coupling coil 24. The coupling coil 24 is used to receive external electric energy and send the detection signal of the pressure sensor 28. The input end of the power supply circuit 25 is connected to the coupling coil 24, and the output end of the power supply circuit 25 is respectively connected to the microcontroller 27 and the pressure sensor 28. The microcontroller 27 is respectively connected to the load modulation circuit 26 and the pressure sensor 28. The input end of the load modulation circuit 26 is connected to the microcontroller 27, and the output end of the load modulation circuit 26 is connected to the coupling coil 24. In actual implementation, there can be two coupling coils 24, namely a first coupling coil and a second coupling coil, wherein the first coupling coil is used in the electric energy receiving circuit to receive external electric energy, and the second coupling coil is used in the signal sending circuit to send the detection signal of the pressure sensor 28. The working process and structure of the pressure detection device are the same as those of the first embodiment, and will not be repeated here.

[0048] The transceiver device includes a high-frequency oscillator 31, a high-frequency amplifier 32, a parallel resonant coil 33, an amplification and detection circuit 34, a shaping circuit 35, an external microcontroller 36 and a transmission circuit 37 which are connected in sequence. The frequency source of the high-frequency oscillator 31 is processed by the high-frequency amplifier 32 and then coupled to the coupling coil 24 of the pressure detection device through the parallel resonant coil 33 to realize the transmission of electrical energy.

[0049] The detection signal of the pressure detection device is sent to the parallel resonant coil 33 through the inductive coupling effect of the coupling coil 24 and the parallel resonant coil 33. After the demodulation of the low-frequency signal is realized by the amplification detection circuit 34, the detection data is further read by Schmidt shaping through the shaping circuit 35, and then sent to the transmission circuit 37 through the external microcontroller 36, and transmitted to the corresponding components through the transmission circuit 37, such as being transmitted to the display for display. The external microcontroller 36 can adopt a microcontroller unit (MCU), which has low power consumption and can obtain a longer transmission distance of electric energy and data. The transceiver can be set on a shoulder strap or a chest strap to achieve portability.

[0050] The above embodiments are merely illustrative of the principles and effects of the present application and are not intended to limit the present application. Anyone familiar with the technology may modify or change the above embodiments without violating the spirit and scope of the present application. Therefore, all equivalent modifications or changes made by a person of ordinary skill in the art without departing from the spirit and technical ideas disclosed in the present application shall still be covered by the claims of the present application.

Claims

1. A cardiac shunt, characterized in that: It includes a bracket and a pressure detection device, wherein the pressure detection device includes a flexible circuit board, an electric energy receiving circuit, a signal sending circuit and a pressure sensor; The stent comprises a stent body and a stent fixing part, the stent body has a channel for redistributing atrial blood flow, and the stent fixing part is arranged at both ends of the channel of the stent body; The components in the electric energy receiving circuit and the signal sending circuit are arranged on the flexible circuit board, and the flexible circuit board is fixed on the bracket fixing part and the bracket body; The pressure sensor is connected to the electric energy receiving circuit and the signal sending circuit respectively, and is arranged at one end of the channel of the bracket; The flexible circuit board includes a first part, a second part and a third part, the second part and the third part are arranged at the same side of the first part with a spacing; the first part is fixed to the outer wall of one end of the bracket body, the second part is fixed to the bracket fixing part, and the third part extends to one end of the channel of the bracket; the components in the electric energy receiving circuit and the signal sending circuit are arranged in the first part and the second part, and the pressure sensor is arranged in the third part.

2. The cardiac shunt according to claim 1, characterized in that: The first part surrounds the bracket body and is fixed.

3. The cardiac shunt according to claim 1, characterized in that: The bracket fixing portion includes a plurality of extension arms arranged at intervals along the circumference of the channel, which are symmetrically arranged between the extension arms at both ends of the channel and extend toward each other. The second portion of the flexible circuit board is fixed to a side of the extension arm facing the outer wall of the bracket body, and the third portion of the flexible circuit board extends from a gap between adjacent extension arms to one end of the channel of the bracket.

4. The cardiac shunt according to claim 3, characterized in that: There are two second parts, and the bracket fixing parts arranged at both ends of the bracket body each include six extension arms, and the two second parts are respectively fixed on the two extension arms at the same end of the bracket body.

5. The cardiac shunt according to any one of claims 1 to 4, characterized in that: The electric energy receiving circuit includes a first coupling coil and a power supply circuit, the first coupling coil is used to receive external electric energy, the input end of the power supply circuit is connected to the first coupling coil, and the output end of the power supply circuit is respectively connected to the signal sending circuit and the pressure sensor.

6. The cardiac shunt according to claim 5, characterized in that: The signal sending circuit includes a microcontroller, a load modulation circuit and a second coupling coil. The microcontroller is connected to the load modulation circuit and the pressure sensor respectively. The input end of the load modulation circuit is connected to the microcontroller, and the output end of the load modulation circuit is connected to the second coupling coil. The second coupling coil is used to send the detection signal of the pressure sensor.

7. The cardiac shunt according to claim 6, characterized in that: The first coupling coil and the second coupling coil are the same coil.

8. The cardiac shunt according to claim 6, characterized in that: The first coupling coil and the second coupling coil both include a magnetic sheet and a coil. The coil is arranged in the channel of the bracket and extends axially and spirally along the inner wall of the channel. The magnetic sheet is cylindrical and fixed on the inner side of the coil. Both ends of the coil are connected to the pins on the flexible circuit board.

9. A left atrial pressure monitoring system, characterized in that: It comprises a transceiver and a cardiac shunt as described in any one of claims 1-8, wherein the transceiver is wirelessly connected to a pressure detection device of the cardiac shunt, and the transceiver is used to provide electrical energy to an electrical energy receiving circuit of the pressure detection device, and to receive a pressure detection signal sent by a signal sending circuit of the pressure detection device.

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