Anti-hair loss care composition and its preparation method and application

By combining an amino acid surfactant with an alkyl glycoside surfactant and adding a pentaerythritol stearate thickener, an anti-hair loss care composition is prepared, which solves the problem of poor anti-hair loss effect in the prior art and achieves an anti-hair loss care effect with good thickening and stability.

CN115887272BActive Publication Date: 2025-09-12GUANGZHOU SHIHANG BIOTECH CO LTD
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Patent Information

Application Number
CN202211575887.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-12-09
Publication Date
2025-09-12
Estimated Expiration
2042-12-09

AI Technical Summary

Technical Problem

The effects of ginger extract and caffeine in existing anti-hair loss shampoos are not significant, sulfate anionic surfactants are highly irritating, and adenosine is easily precipitated in shampoo and reduces viscosity, resulting in poor anti-hair loss effect.

Method used

An anti-hair loss care composition is prepared by combining an amino acid surfactant with an alkyl glycoside surfactant, adding a pentaerythritol stearate thickener, mixing adenosine and polyols, avoiding irritating ingredients, and enhancing viscosity and stability.

Benefits of technology

The product can gently clean the scalp, supplement nutrition to hair roots, reduce hair loss, and has a significant thickening effect. The composition has good stability and no side effects.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention provides an anti-hair loss care composition comprising the following components, measured by weight: 0.5% to 0.75% adenosine, 1% to 10% polyol, 0.5% to 3% pentaerythritol stearate, 30% to 50% surfactant, 0.3% to 1% cationic conditioning agent, 0.05% to 0.15% chelating agent, 0.2% to 1% softening agent, 2% to 4% auxiliary agent, and the balance water; wherein the surfactant is selected from one or more of an amino acid surfactant and an alkyl glycoside surfactant. The composition has a strong anti-hair loss effect, high viscosity, and good stability.
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Description

Technical Field

[0001] The present invention relates to the technical field of fine chemicals, and in particular to an anti-hair loss care composition and a preparation method and application thereof. Background Art

[0002] As an integral part of our body structure, hair plays a vital role in our daily lives. Hair not only directly protects the scalp but also acts as a buffer against external forces acting on the scalp, thereby reducing damage and protecting the head. Furthermore, hair has a crucial aesthetic function as well as unique and important social and psychological functions. Traditional Chinese Medicine (TCM) believes that hair is the product of blood, and that the kidneys store essence, the essence of which is found in hair. Hair growth depends on the nourishment of essence and blood. Thick, lustrous hair symbolizes health and creates a positive image. Different hair shapes and conditions create different impressions. Healthy, beautiful hair enhances interpersonal confidence. Conversely, various hair disorders, such as hair loss and thinning hair, can lead to negative emotions like low self-esteem and anxiety, and in severe cases, can even affect social interaction. With changes in living environments and pressures, hair loss and other conditions are becoming increasingly common among young people.

[0003] Traditional anti-hair loss shampoos often contain ginger extract in an attempt to prevent hair loss. However, 6-gingerol, the main active ingredient in ginger, has little effect on promoting hair growth and may even inhibit hair growth. Some traditional anti-hair loss shampoos also add caffeine to their formulas. While caffeine shampoos do have the potential to promote hair growth, the ultimate hair loss prevention effect has not met expectations. Furthermore, some commercially available anti-hair loss shampoos contain sulfate anionic surfactants and use formaldehyde-releasing preservatives such as kasone and DMDM ​​hydantoin. These are highly irritating and, in turn, reduce their effectiveness.

[0004] Other traditional technologies attempt to improve hair loss prevention by adding adenosine to shampoo. However, adenosine easily precipitates during storage and has a strong viscosity-reducing effect in shampoo. Adding polyols to the shampoo further reduces viscosity, while amino acid shampoo systems inherently struggle to thicken. This complicates the use of adenosine in amino acid shampoo products. Consequently, currently available adenosine hair loss prevention shampoos almost all utilize sulfate systems. Sulfate anionic surfactants are inherently irritating to the scalp, resulting in limited hair loss prevention effectiveness. Summary of the Invention

[0005] Based on this, the present invention provides an anti-hair loss care composition, which has a strong anti-hair loss effect, high viscosity and good stability.

[0006] The present invention is achieved through the following technical solutions.

[0007] An anti-hair loss care composition, comprising the following components in percentage by weight:

[0008]

[0009] Wherein, the surfactant is selected from one or more of amino acid surfactants and alkyl glycoside surfactants.

[0010] In one embodiment, the polyol is selected from one or more of glycerol, sorbitol, butylene glycol and propylene glycol.

[0011] In one embodiment, the amino acid surfactant is selected from one or more of cocamidopropyl betaine, sodium lauroyl sarcosinate, sodium lauryl glycol carboxylate and sodium cocoyl methyl taurate;

[0012] The alkyl glucoside surfactant is selected from one or more of decyl glucoside, lauryl glucoside and coconut glucoside.

[0013] In one embodiment, the cationic conditioning agent is selected from one or more of guar hydroxypropyltrimonium chloride and polyquaternium-10.

[0014] In one embodiment, the chelating agent is selected from one or more of disodium EDTA, tetrasodium EDTA and hydroxyethylethylenediaminetriacetic acid.

[0015] In one embodiment, the softener is selected from one or more of PPG-3 caprylyl ether, PEG-7 glyceryl cocoate, and dimethicone PEG-7 cocoate.

[0016] In one embodiment, the auxiliary agent includes one or more of a pH regulator, an active ingredient, a preservative, and a flavor.

[0017] In one embodiment, the auxiliary agent satisfies one or more of the following conditions:

[0018] (1) The pH regulator is selected from one or more of citric acid, phosphoric acid, sodium hydroxide and triethanolamine;

[0019] (2) The active ingredient is selected from one or more of adenosine, oxidized keratin, hydrolyzed keratin, Platycladus orientalis leaf extract, Swertia japonica extract, and Morus alba root extract;

[0020] (3) The preservative is selected from one or more of sodium benzoate, phenoxyethanol, ethylhexylglycerin and DMDM ​​hydantoin.

[0021] The present invention also provides a method for preparing the above-mentioned anti-hair loss composition, comprising the following steps:

[0022] Step S1, mixing water, the polyol, the cationic conditioning agent, the surfactant and the chelating agent to prepare a first mixture;

[0023] Step S2, mixing the first mixed material, the surfactant and the pentaerythritol stearate at a temperature of 80° C. to 85° C., and cooling the mixture to 68° C. to 72° C. to prepare a second mixed material;

[0024] Step S3, mixing the second mixed material, the surfactant, the softener and the adenosine, and cooling the mixture to 43° C. to 47° C. to prepare a third mixed material;

[0025] Step S4, mixing the third mixed material with the auxiliary agent;

[0026] Wherein, the mass ratio of the surfactant in step S1, the surfactant in step S2 and the surfactant in step S3 is (5-10):(15-20):1.

[0027] The present invention also provides use of the above-mentioned anti-hair loss care composition in the preparation of shampoo, hair conditioner, hair mask or hair care essential oil.

[0028] Compared with the prior art, the anti-hair loss care composition of the present invention has the following beneficial effects:

[0029] The present invention adds adenosine to the hair care composition to enhance the anti-hair loss effect. Pentaerythritol stearate is selected as a thickener and compounded with adenosine, polyols, amino acid surfactants, alkyl glycoside surfactants and other adjuvants. The composition can gently cleanse the scalp and supplement the scalp with nutrients, thereby strengthening the hair roots and reducing hair loss. At the same time, the composition can also effectively thicken the hair to avoid a significant decrease in viscosity.

[0030] Furthermore, the anti-hair loss care composition of the present invention has good stability, does not require the addition of highly irritating or harmful additives, and does not produce any side effects for users in the long term. DETAILED DESCRIPTION

[0031] To facilitate understanding of the present invention, the present invention will be described more fully below. Preferred embodiments of the present invention are provided. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to provide a more thorough and comprehensive understanding of the disclosure of the present invention.

[0032] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of the features. In the description of the invention, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined. In the description of the present invention, the meaning of "several" is at least one, such as one, two, etc., unless otherwise clearly and specifically defined.

[0033] The terms "preferably," "more preferably," and the like, used herein refer to embodiments of the present invention that may provide certain benefits under certain circumstances. However, other embodiments may also be preferred under the same or other circumstances. Furthermore, the recitation of one or more preferred embodiments does not imply that other embodiments are not useful, nor is it intended to exclude other embodiments from the scope of the present invention.

[0034] When a numerical range is disclosed herein, the range is considered continuous and includes the minimum and maximum values ​​of the range, as well as every value between such minimum and maximum values. Further, when a range refers to an integer, every integer between the minimum and maximum values ​​of the range is included. In addition, when multiple ranges are provided to describe a feature or characteristic, the ranges can be combined. In other words, unless otherwise indicated, all ranges disclosed herein are understood to include any and all subranges subsumed therein.

[0035] Unless otherwise indicated, all percentages, fractions, and ratios are calculated based on the total weight of the compositions of the present invention. Unless otherwise indicated, all masses relating to listed ingredients are given as active ingredients and therefore do not include solvents or byproducts that may be present in commercially available materials. The term "mass percentage content" may be expressed herein with the symbol "%." All molecular weights herein are weight-average molecular weights expressed in Daltons, unless otherwise indicated. All formulations and testing herein took place at 25°C, unless otherwise indicated. The terms "comprise," "include," "contain," "have," "have," and other variations herein are intended to encompass non-exclusive inclusions, and do not distinguish between these terms. The term "comprising" means that additional steps and ingredients that do not affect the end result may be added. The compositions and methods / processes of the present invention comprise, consist of, and consist essentially of the essential elements and limitations described herein, as well as any additional or optional ingredients, components, steps, or limitations described herein. The terms "efficacy," "performance," "effect," and "efficacy" are not used herein to distinguish between.

[0036] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which the present invention pertains. The terms used herein in the specification of the present invention are for the purpose of describing specific embodiments only and are not intended to limit the present invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0037] The present invention provides an anti-hair loss care composition, which comprises the following components in percentage by weight:

[0038]

[0039] Wherein, the surfactant is selected from one or more of amino acid surfactants and alkyl glycoside surfactants.

[0040] In a specific example, the polyol is selected from one or more of glycerol, sorbitol, butylene glycol and propylene glycol.

[0041] In a specific example, the amino acid surfactant is selected from one or more of cocamidopropyl betaine, sodium lauroyl sarcosinate, sodium lauryl glycol carboxylate and sodium cocoyl methyl taurate.

[0042] In a specific example, the alkyl glucoside surfactant is selected from one or more of decyl glucoside, lauryl glucoside and coconut glucoside.

[0043] In a specific example, the cationic conditioning agent is selected from one or more of guar hydroxypropyltrimonium chloride and polyquaternium-10.

[0044] In a specific example, the chelating agent is selected from one or more of disodium EDTA, tetrasodium EDTA and hydroxyethylethylenediaminetriacetic acid.

[0045] In a specific example, the softener is selected from one or more of PPG-3 caprylyl ether, PEG-7 glyceryl cocoate, and dimethicone PEG-7 cocoate.

[0046] In a specific example, the auxiliary agent includes one or more of a pH adjuster, an active ingredient, a preservative, and a flavor.

[0047] In a specific example, the pH adjuster is selected from one or more of citric acid, phosphoric acid, sodium hydroxide and triethanolamine.

[0048] In a specific example, the active ingredient is selected from one or more of adenosine, oxidized keratin, hydrolyzed keratin, Platycladus orientalis leaf extract, Swertia japonica extract, and Morus alba root extract.

[0049] In a specific example, the preservative is selected from one or more of sodium benzoate, phenoxyethanol, ethylhexylglycerin and DMDM ​​hydantoin.

[0050] Preferably, the preservative is a mixture of sodium benzoate and phenoxyethanol. More specifically, the preservative is a mixture of sodium benzoate and phenoxyethanol in a ratio of 0.7:1.

[0051] In a specific example, the anti-hair loss composition comprises the following components by weight:

[0052]

[0053]

[0054] The present invention also provides a method for preparing the above-mentioned anti-hair loss care composition, comprising the following steps:

[0055] Step S1, mixing water, polyol, cationic conditioning agent, surfactant and chelating agent to prepare a first mixture;

[0056] Step S2: mixing the first mixed material, the surfactant and pentaerythritol stearate at a temperature of 80° C. to 85° C., and cooling the mixture to 68° C. to 72° C. to prepare a second mixed material;

[0057] Step S3, mixing the second mixed material, the surfactant, the softener and the adenosine, and cooling the mixture to 43° C. to 47° C. to prepare a third mixed material;

[0058] Step S4, mixing the third mixed material with an auxiliary agent;

[0059] The mass ratio of the surfactant in step S1, the surfactant in step S2 and the surfactant in step S3 is (5-10):(15-20):1.

[0060] More specifically, the mass ratio of the surfactant in step S1, the surfactant in step S2 and the surfactant in step S3 is (7-8):(17-18):1.

[0061] In a specific example, the surfactant in step S1 is selected from amino acid surfactants. More specifically, the surfactant in step S1 is cocamidopropyl betaine.

[0062] In a specific example, the surfactant in step S2 is selected from an amino acid surfactant. More specifically, the surfactant in step S2 is one or more of sodium lauroyl sarcosinate, sodium lauryl glycol carboxylate, and sodium cocoyl methyl taurate.

[0063] In a specific example, the surfactant in step S3 is selected from alkyl glycoside surfactants. More specifically, the surfactant in step S3 is decyl glucoside.

[0064] In a specific example, the softener in step S3 is selected from one or more of PPG-3 caprylyl ether, PEG-7 glyceryl cocoate, and dimethicone PEG-7 cocoate.

[0065] The present invention also provides the use of the anti-hair loss care composition in the preparation of shampoo, hair conditioner, hair mask or hair care essential oil.

[0066] The anti-hair loss care composition and its preparation method of the present invention are further described in detail below with reference to specific examples. The raw materials used in the following examples, unless otherwise specified, are all commercially available products.

[0067] Example 1

[0068] This embodiment provides an anti-hair loss shampoo, and the weight percentage of each component is shown in Table 1.

[0069] The preparation method is as follows:

[0070] (1) Equipment and weighing tools should be cleaned and disinfected and kept ready for use;

[0071] (2) After adding the water of phase A into the beaker, the remaining raw materials of phase A, polyquaternium-10, cocamidopropyl betaine, polyol, and chelating agent are added to the beaker in sequence while stirring, and stirred evenly; the polyol is to prevent adenosine from precipitating at low temperatures;

[0072] (3) Add the ingredients of phase B in sequence, heat to 80-85°C, stir until completely dissolved, and begin stirring to cool; PEG-150 pentaerythritol tetrastearate is added for thickening;

[0073] (4) Cool to 70°C, add the raw materials of phase C in sequence, stir evenly and continue to cool;

[0074] (5) Cool down to 45°C, add Phase D raw materials, and stir for 15 minutes until uniform. Sample inspection, and discharge if qualified.

[0075] Example 2

[0076] This embodiment provides an anti-hair loss shampoo, and the weight percentage of each component is shown in Table 1.

[0077] The preparation method is as follows:

[0078] (1) Equipment and weighing tools should be cleaned and disinfected and kept ready for use;

[0079] (2) After adding the water of phase A into the beaker, the remaining raw materials of phase A, polyquaternium-10, cocamidopropyl betaine, polyol, and chelating agent are added to the beaker in sequence while stirring, and stirred evenly; the polyol is to prevent adenosine from precipitating at low temperatures;

[0080] (3) Add the ingredients of phase B in sequence, heat to 80-85°C, stir until completely dissolved, and begin stirring to cool; PEG-150 pentaerythritol tetrastearate is added for thickening;

[0081] (4) Cool to 70°C, add the raw materials of phase C in sequence, stir evenly and continue to cool;

[0082] (5) Cool down to 45°C, add Phase D raw materials, and stir for 15 minutes until uniform. Sample inspection, and discharge if qualified.

[0083] Example 3

[0084] This embodiment provides an anti-hair loss shampoo, and the weight percentage of each component is shown in Table 1.

[0085] The preparation method is as follows:

[0086] (1) Equipment and weighing tools should be cleaned and disinfected and kept ready for use;

[0087] (2) After adding the water of phase A into the beaker, the remaining raw materials of phase A, polyquaternium-10, cocamidopropyl betaine, polyol, and chelating agent are added to the beaker in sequence while stirring, and stirred evenly; the polyol is to prevent adenosine from precipitating at low temperatures;

[0088] (3) Add the ingredients of phase B in sequence, heat to 80-85°C, stir until completely dissolved, and begin stirring to cool; PEG-150 pentaerythritol tetrastearate is added for thickening;

[0089] (4) Cool to 70°C, add the raw materials of phase C in sequence, stir evenly and continue to cool;

[0090] (5) Cool down to 45°C, add Phase D raw materials, and stir for 15 minutes until uniform. Sample inspection, and discharge if qualified.

[0091] Example 4

[0092] This embodiment provides an anti-hair loss shampoo, and the weight percentage of each component is shown in Table 1.

[0093] The preparation method is as follows:

[0094] (1) Equipment and weighing tools should be cleaned and disinfected and kept ready for use;

[0095] (2) After adding the water of phase A into the beaker, the remaining raw materials of phase A, polyquaternium-10, cocamidopropyl betaine, polyol, and chelating agent are added to the beaker in sequence while stirring, and stirred evenly; the polyol is to prevent adenosine from precipitating at low temperatures;

[0096] (3) Add the ingredients of phase B in sequence, heat to 80-85°C, stir until completely dissolved, and begin stirring to cool; PEG-150 pentaerythritol tetrastearate is added for thickening;

[0097] (4) Cool to 70°C, add the raw materials of phase C in sequence, stir evenly and continue to cool;

[0098] (5) Cool down to 45°C, add Phase D raw materials, and stir for 15 minutes until uniform. Sample inspection, and discharge if qualified.

[0099] Example 5

[0100] This embodiment provides an anti-hair loss shampoo, and the weight percentage of each component is shown in Table 2.

[0101] The preparation method is as follows:

[0102] (1) Equipment and weighing tools should be cleaned and disinfected and kept ready for use;

[0103] (2) After adding the water of phase A into the beaker, the remaining raw materials of phase A, polyquaternium-10, cocamidopropyl betaine, polyol, and chelating agent are added to the beaker in sequence while stirring, and stirred evenly; the polyol is to prevent adenosine from precipitating at low temperatures;

[0104] (3) Add the ingredients of phase B in sequence, heat to 80-85°C, stir until completely dissolved, and begin stirring to cool; PEG-150 pentaerythritol tetrastearate is added for thickening;

[0105] (4) Cool to 70°C, add the raw materials of phase C in sequence, stir evenly and continue to cool;

[0106] (5) Cool down to 45°C, add Phase D raw materials, and stir for 15 minutes until uniform. Sample inspection, and discharge if qualified.

[0107] Example 6

[0108] This embodiment provides an anti-hair loss shampoo, and the weight percentage of each component is shown in Table 2.

[0109] The preparation method is as follows:

[0110] (1) Equipment and weighing tools should be cleaned and disinfected and kept ready for use;

[0111] (2) After adding the water of phase A into the beaker, the remaining raw materials of phase A, polyquaternium-10, cocamidopropyl betaine, polyol, and chelating agent are added to the beaker in sequence while stirring, and stirred evenly; the polyol is to prevent adenosine from precipitating at low temperatures;

[0112] (3) Add the ingredients of phase B in sequence, heat to 80-85°C, stir until completely dissolved, and begin stirring to cool; PEG-150 pentaerythritol tetrastearate is added for thickening;

[0113] (4) Cool to 70°C, add the raw materials of phase C in sequence, stir evenly and continue to cool;

[0114] (5) Cool down to 45°C, add Phase D raw materials, and stir for 15 minutes until uniform. Sample inspection, and discharge if qualified.

[0115] Comparative Example 1

[0116] This comparative example provides an anti-hair loss shampoo, and the weight percentage of each component is shown in Table 2.

[0117] The preparation method is as follows:

[0118] (1) Equipment and weighing tools should be cleaned and disinfected and kept ready for use;

[0119] (2) After adding the water of phase A into the beaker, the remaining raw materials of phase A, polyquaternium-10, cocamidopropyl betaine, polyol, and chelating agent are added to the beaker in sequence while stirring, and stirred evenly; the polyol is to prevent adenosine from precipitating at low temperatures;

[0120] (3) Add the ingredients of phase B in sequence, heat to 80-85°C, stir until completely dissolved, and begin stirring to cool; PEG-120 is added for thickening;

[0121] (4) Cool to 70°C, add the raw materials of phase C in sequence, stir evenly and continue to cool;

[0122] (5) Cool down to 45°C, add Phase D raw materials, and stir for 15 minutes until uniform. Sample inspection, and discharge if qualified.

[0123] Comparative Example 2

[0124] This comparative example provides an anti-hair loss shampoo, and the weight percentage of each component is shown in Table 2.

[0125] The preparation method is as follows:

[0126] (1) Equipment and weighing tools should be cleaned and disinfected and kept ready for use;

[0127] (2) After adding the water of phase A into the beaker, the remaining raw materials of phase A, polyquaternium-10, cocamidopropyl betaine, polyol, and chelating agent are added to the beaker in sequence while stirring, and stirred evenly; the polyol is to prevent adenosine from precipitating at low temperatures;

[0128] (3) Add the raw materials of phase B in sequence, heat to 80-85°C, stir until completely dissolved, and start stirring to cool; the purpose of adding cocamidomethyl MEA is to thicken;

[0129] (4) Cool to 70°C, add the raw materials of phase C in sequence, stir evenly and continue to cool;

[0130] (5) Cool down to 45°C, add Phase D raw materials, and stir for 15 minutes until uniform. Sample inspection, and discharge if qualified.

[0131] Table 1

[0132]

[0133] Table 2

[0134]

[0135] Effect verification test

[0136] Effect verification experiments were conducted on the above Examples 1-6 and Comparative Examples 1-2, including physical and chemical tests and anti-shedding tests.

[0137] 1. Physical and chemical test indicators

[0138] (1) Dilute 10 cups of water at 25°C, test with a pH meter, and record the results.

[0139] (2) Viscosity: Model BROOKFIELD, No. 3 rotor, 12 rpm, test and record results;

[0140] The results of physical and chemical tests are shown in Table 3.

[0141] Table 3

[0142] Indicator average pH Viscosity / mPa.s Example 1 5.68 3005 Example 2 5.68 2475 Example 3 5.71 4597 Example 4 5.63 4925 Example 5 5.66 2854 Example 6 5.64 3668 Comparative Example 1 5.69 1768 Comparative Example 2 5.70 2122

[0143] Comparing Examples 4 and 5, we can see that increasing the amount of polyol reduces viscosity; comparing Examples 1 and 2, we can see that increasing the amount of adenosine also reduces viscosity. Comparing the viscosity results of Comparative Examples 1 and 2 with the viscosity of Example 5 demonstrates that PEG-150 pentaerythritol tetrastearate is an irreplaceable thickener in this formulation. A certain ratio of PEG-150 pentaerythritol tetrastearate and citric acid mitigates the severe viscosity-reducing effect caused by the addition of adenosine and polyols, stabilizing the formulation and maintaining certain physical and chemical properties.

[0144] 2. Anti-shedding test

[0145] Subjects should not wash their hair within 48±4 hours before screening and each visit during the trial, and the time without washing hair before each visit should be basically consistent. They should not comb their hair on the day of the visit; they should not have their hair cut within 2 weeks before each visit evaluation during the trial; they should not perform any hair care or hairdressing measures during the trial, nor should they receive any anti-hair loss or hair growth treatments; they should maintain their original lifestyle habits during the trial and avoid large mood swings.

[0146] (1) 140 subjects with mild hair loss were divided into 7 groups, with 20 subjects in each group. Each group was asked to try the shampoo prepared in the above six embodiments for 3 months respectively.

[0147] (2) Two-week washout test: Wash once every two days, using 10 g of the shampoo of Comparative Example 1 each time;

[0148] (3) After the washout period, the subjects entered the experimental group for a ten-week trial: the subjects washed their hair once every two days, using 10 g of the shampoo of Examples 1-6 and Comparative Example 1 each time. Requirement: From the washout period onwards, the subjects were not allowed to wash their hair within 48 hours after using the trial shampoo, and were not allowed to comb their hair after 48 hours;

[0149] (4) Special person combing requirements: specific specifications of combs and specific personnel. Comb from left front to left back, right front to right back, at a constant speed 60 times (30 times on each side);

[0150] (5) Collect and count the fallen hair.

[0151] The anti-shedding test results are shown in Table 4.

[0152] Table 4

[0153] Average amount of hair loss Week 2 First month Second month Third month Example 1 120 101 93 87 Example 2 130 118 106 85 Example 3 110 98 86 73 Example 4 108 92 79 68 Example 5 130 119 108 93 Example 6 120 98 73 56 Comparative Example 1 125 113 94 74

[0154] After using shampoo containing adenosine for 3 months, the symptoms of all people with mild hair loss will improve, and the improvement effect will become more obvious as the amount of adenosine added increases.

[0155] The technical features of the above-mentioned embodiments can be combined arbitrarily. In order to make the description concise, not all possible combinations of the technical features in the above-mentioned embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0156] The embodiments described above only express several implementation methods of the present invention, which are convenient for understanding the technical solutions of the present invention in a specific and detailed manner, but they cannot be understood as limiting the scope of protection of the invention patent. It should be pointed out that for ordinary technicians in this field, without departing from the concept of the present invention, several variations and improvements can be made, which all fall within the scope of protection of the present invention. It should be understood that the technical solutions obtained by those skilled in the art through logical analysis, reasoning or limited experiments on the basis of the technical solutions provided by the present invention are all within the scope of protection of the claims attached to the present invention. Therefore, the scope of protection of the patent of the present invention shall be based on the content of the attached claims, and the description can be used to interpret the content of the claims.

Claims

1. An anti-hair loss care composition, characterized in that In terms of weight percentage, it is composed of the following components: Wherein, the pentaerythritol stearate is PEG-150 pentaerythritol tetrastearate; The surfactant is an amino acid surfactant and an alkyl glycoside surfactant; The pH regulator is selected from one or more of citric acid, phosphoric acid, sodium hydroxide and triethanolamine; The active ingredient is selected from one or more of oxidized keratin, hydrolyzed keratin, Platycladus orientalis leaf extract, Swertia japonica extract and mulberry root extract.

2. The anti-hair loss composition according to claim 1, characterized in that The polyol is selected from one or more of glycerol, sorbitol, butylene glycol and propylene glycol.

3. The anti-hair loss composition according to claim 1, characterized in that The amino acid surfactant is selected from one or more of cocamidopropyl betaine, sodium lauroyl sarcosinate, sodium lauryl glycol carboxylate and sodium cocoyl methyl taurate; The alkyl glucoside surfactant is selected from one or more of decyl glucoside, lauryl glucoside and coconut glucoside.

4. The anti-hair loss composition according to claim 1, characterized in that The cationic conditioning agent is selected from one or more of guar hydroxypropyltrimonium chloride and polyquaternium-10.

5. The anti-hair loss composition according to claim 1, characterized in that The chelating agent is selected from one or more of disodium EDTA, tetrasodium EDTA and hydroxyethylethylenediaminetriacetic acid.

6. The anti-hair loss composition according to claim 1, characterized in that The softener is selected from one or more of PPG-3 caprylyl ether, PEG-7 glyceryl cocoate and dimethicone PEG-7 cocoate.

7. The anti-hair loss composition according to claim 6, characterized in that The preservative is selected from one or more of sodium benzoate, phenoxyethanol, ethylhexylglycerin and DMDM ​​hydantoin.

8. A method for preparing the anti-hair loss composition according to any one of claims 1 to 7, characterized in that: The steps include: Step S1, mixing water, the polyol, the cationic conditioning agent, cocamidopropyl betaine and the chelating agent to prepare a first mixture; Step S2, mixing the first mixture, sodium lauroyl sarcosinate, sodium lauryl glycol carboxylate, sodium cocoyl methyl taurate and pentaerythritol stearate at a temperature of 80° C. to 85° C., and cooling the mixture to 68° C. to 72° C. to prepare a second mixture; Step S3, mixing the second mixed material, decyl glucoside, the softener and the adenosine, and cooling the mixture to 43° C. to 47° C. to prepare a third mixed material; Step S4, mixing the third mixed material with the pH regulator, the active ingredient, the preservative and the flavor; The mass ratio of the surfactant in step S1, the surfactant in step S2 and the surfactant in step S3 is (5-10):(15-20):1; the surfactant in step S1 is the cocamidopropyl betaine, the surfactant in step S2 is the sodium lauroyl sarcosinate, the sodium lauryl glycol carboxylate and the sodium cocoyl methyl taurate taurate, and the surfactant in step S3 is the decyl glucoside.

9. Use of the anti-hair loss care composition according to any one of claims 1 to 7 in the preparation of shampoo, hair conditioner, hair mask or hair care essential oil.

Citation Information

Patent Citations

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