Multi-channel full-automatic split type actinide separation solid phase extraction instrument

Abstract

The present application relates to a kind of multi-channel full-automatic split type actinide separation solid-phase extraction instrument, belong to nuclide separation equipment technical field, the extraction instrument includes multiple channel modules, each channel module includes multi-port solenoid valve and injection pump, the channel of multi-port solenoid valve is sequentially communicated with injection pump, sample liquid bottle inlet end, chromatographic column inlet end, reagent bottle one-to-one correspondence;Injection pump front end is equipped with three-way valve head, and other two ports are connected with air pipe and multi-port solenoid valve respectively;Chromatographic column inlet end is connected with three-way, and the two import ends of three-way are communicated with the third channel of multi-port solenoid valve and sample liquid bottle outlet end respectively;The multi-port solenoid valve and injection pump of each channel module are connected with main controller using different bus control interface respectively, and are sequentially set to different ID by hardware address respectively.The present application can reduce the human cost, instability of manual operation and radiation damage to workers when manually operating to the greatest extent when carrying out chemical separation to radionuclide in solution.

Description

Technical Field

[0001] This invention belongs to the field of radionuclide separation equipment technology, specifically a multi-channel fully automatic split-type solid-phase extraction instrument for separating actinides. Background Technology

[0002] Actinide radionuclides are key radionuclides of concern in environmental monitoring and effluent monitoring. Therefore, in accordance with relevant radioactive emission regulatory standards and regulations, all environmental monitoring stations and nuclear power plants must monitor key radionuclides of concern. 239 Pu、 240 Pu、 241 Regular monitoring of radionuclides (such as Am) and timely analysis of monitoring data are crucial to prevent radiation hazards to personnel and the surrounding environment. Therefore, regularly collecting samples from the environment surrounding nuclear facilities, the ecological environment, and effluents from nuclear facilities, and testing key radionuclides within these samples, is an important aspect of radiation hazard monitoring. The radiochemical separation of low-level radionuclides in samples heavily relies on the experience of chemical operators, requiring systematic training. Furthermore, existing radionuclide analysis methods are mostly manual, requiring multiple manual reagent additions and separation equipment operations, which can pose unnecessary radiation hazards to analysts, especially for samples with high activity. These methods are insufficient to address the challenge of rapid and accurate analysis of radionuclides in large quantities of samples in the nuclear industry. Against this market demand, automated solid-phase extraction instruments for radionuclides have emerged.

[0003] However, the variety of automated solid-phase extraction instruments for radioactive nuclides currently available in the domestic and international markets is limited, and most cannot solve the problem of cross-contamination between samples during chemical processing of low-content samples. Furthermore, structurally, many fully automated solid-phase extraction instruments for radioactive nuclides on the market do not completely isolate their electronic components from chemical reagents, causing the electronic components to be frequently exposed to strong acid environments. This significantly increases the likelihood of instrument malfunction and shortens the lifespan of electronic components. Summary of the Invention

[0004] To address the shortcomings of existing technologies, the present invention aims to provide a multi-channel fully automated split-type solid-phase extraction instrument for separating actinide nuclides. This extraction instrument can minimize the labor costs associated with manual operation, the instability of manual sample preparation, and radiation damage to workers. Its user-friendly structure and pipeline design can solve the fatal flaw of cross-contamination in existing similar instruments.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A multi-channel fully automated split-type solid-phase extraction instrument for separating actinides, the extractor comprising a main controller, a human-machine interface, and multiple channel modules, each channel module including a multi-port solenoid valve, a syringe pump, a chromatography column, multiple reagent bottles, sample bottles, and multiple collection bottles, wherein:

[0007] The multi-port solenoid valve has multiple channels, namely the first channel, the second channel, ... the Nth channel. The first channel serves as a common channel and is connected to the injection pump. The second channel is connected to the inlet end of the sample bottle. The third channel is connected to the inlet end of the chromatography column. The remaining channels are connected to the multiple reagent bottles one by one.

[0008] The injection pump has a built-in three-way valve head at the front end. The three-way valve head has port a, port b and port c. Port a is connected to the injection pump. Port b and port c are respectively connected to the air tube and the first channel of the multi-way solenoid valve.

[0009] The inlet end of the chromatography column is connected to a three-way valve, and the two inlet ends of the three-way valve are respectively connected to the third channel of the multi-way solenoid valve and the outlet end of the sample bottle; the collection bottle is located below the chromatography column and is used to collect the effluent from the chromatography column.

[0010] Each channel module's multi-port solenoid valve and injection pump are connected to the main controller via different bus control interfaces. Communication cables for identical components in all channel modules are connected in parallel. The two control groups for multi-port solenoid valves and injection pumps are set to different IDs via hardware addresses, thereby enabling overall control of all channel modules and separate control of individual channel modules.

[0011] Furthermore, as described above, the multi-channel fully automated split-type actinide solid-phase extraction instrument includes an electrical control cabinet and an experimental cabinet. The multi-port solenoid valve, injection pump, main controller, human-machine interface, and reagent bottles are integrated in the electrical control cabinet, while the chromatography column, sample bottle, and collection bottle are integrated in the experimental cabinet. The electrical control cabinet and the experimental cabinet are connected by pipelines and cables.

[0012] Furthermore, as described above, the multi-channel fully automated split-type actinide solid-phase extraction instrument has equal pipe lengths in each channel module to ensure the accuracy of multi-channel solution column throughput.

[0013] Furthermore, in the multi-channel fully automated split-type actinide solid-phase extraction instrument described above, the highest point of the liquid level in the sample bottle is lower than the lowest point of the chromatography column, to ensure that the sample solution cannot flow through the chromatography column on its own.

[0014] Furthermore, as described above, the multi-channel fully automated split-type actinide solid-phase extraction instrument for separation has a buffer tube installed on the pipeline connecting the first channel of the multi-way solenoid valve and the injection pump. This buffer tube is used to prevent reagents from flowing into the injection pump and thus affecting its accuracy and lifespan, while also avoiding cross-contamination between reagents.

[0015] Furthermore, as described above, the multi-channel fully automated split-type actinide solid-phase extraction instrument has a first one-way valve installed on the pipeline connecting the three-way valve to the third channel of the multi-way solenoid valve, and a second one-way valve installed on the pipeline connecting the three-way valve to the outlet end of the sample bottle.

[0016] Furthermore, as described above, the multi-channel fully automated split-type actinide solid-phase extraction instrument has a switching valve installed on the pipeline between the outlet end of the sample bottle and the second one-way valve to facilitate control of the loading of the sample solution.

[0017] Furthermore, in the multi-channel fully automated split-type actinide solid-phase extraction instrument described above, the sample bottle is equipped with a sieve plate, which is a hydrophilic sieve plate with a pore size of <30μm.

[0018] Furthermore, as described above, the multi-channel fully automated split-type actinide solid-phase extraction instrument for separation also integrates a precision motor guide rail in the experimental cabinet. A tray is fixed on the guide rail, and multiple collection bottles are installed in the tray. The precision motor guide rail can sequentially move the collection bottles in the tray horizontally to directly below the chromatography column to collect the effluent from each step individually.

[0019] The experimental cabinet also integrates a Y-axis robotic arm and a longitudinal motor. The Y-axis robotic arm is connected to the chromatography column and is used to control the vertical movement of the chromatography column. The longitudinal motor can control the Y-axis robotic arm to drive the outlet of the chromatography column down below the mouth of the collection bottle to prevent splashing of the effluent during discharge and causing cross-contamination between the instrument and the sample.

[0020] Furthermore, in the multi-channel fully automated split-type actinide solid-phase extraction instrument described above, the electrical control cabinet also integrates a precision gravity sensor. Each reagent bottle is placed on the precision gravity sensor to compare the remaining reagent volume in the reagent bottle with a set threshold. If the volume is lower than the set threshold, an alert is issued and the experimental process is locked.

[0021] Furthermore, as described above, the multi-channel fully automated split-type actinide solid-phase extraction instrument uses a quick-connect method for easy replacement of the tubing from the sample bottle to the chromatography column.

[0022] Furthermore, in the multi-channel fully automated split-type actinide solid-phase extraction instrument described above, the reagent bottle is externally mounted on the electrical control cabinet, and the sample solution bottle is externally mounted on the experimental cabinet.

[0023] The multi-channel fully automated split-type actinide solid-phase extraction instrument described in this invention has the following significant technical advantages:

[0024] 1. This invention separates the sample solution and the chromatography column washing solution tubing. The sample solution connection tubing can be replaced with a quick-connect method before each experiment. Structurally, this ensures the uniqueness of the tubing through which each sample flows, and can completely solve the problem of cross-contamination between samples.

[0025] 2. This invention designs and installs important electronic components and chemical experimental parts in different chassis, completely isolating the core, easily damaged electronic components from the strong acid environment, thereby increasing the service life and operational stability of the instrument; at the same time, the experimental parts can be placed in a fume hood or a large glove box, effectively reducing the harm to people from radiation operation and reducing personal radiation dose.

[0026] 3. This invention makes the overall structure more compact and small by rationally arranging the pipelines and various components. The experimental cabinet can be placed in a fume hood or glove box for operation, which meets the user's requirements for radiation protection and laboratory operation specifications in actual operation and increases the flexibility of instrument movement and placement. The reagent bottles and sample bottles are placed on the outside of the electrical control cabinet and the experimental cabinet, respectively, which facilitates the addition of solutions and samples before the experiment, making the overall structure more reasonable.

[0027] 4. This invention installs a gravity sensor at the bottom of the reagent bottle, achieving a reagent load-bearing accuracy of 0.1g. If the weight is insufficient, feedback is sent to the control system, avoiding experimental failures caused by the experimenter's failure to add liquid in time.

[0028] 5. The present invention has up to 16 sample preparation channels, allowing multiple samples in a batch to be prepared simultaneously, which not only greatly improves experimental efficiency, but also allows for the operation of all channels under overall control and individual channels under separate control. In practical applications, the number of sample preparation channels can be flexibly controlled according to the actual number of samples analyzed in a single batch, avoiding the ineffective operation of empty sample channels.

[0029] 6. The precision motor of this invention has a control accuracy of ≤0.1mm for the moving distance, which can accurately realize the effective collection of effluent from different steps, and realize the accurate traceability of the target nuclide in different steps of the whole process, avoiding solution loss and instrument contamination caused by misalignment of the chromatography column outlet with the collection bottle. Attached Figure Description

[0030] Figure 1This is a schematic diagram of the liquid circuit connection of one channel module of a multi-channel fully automated split-type actinide solid-phase extraction instrument provided in an embodiment of the present invention;

[0031] Figure 2 A schematic diagram showing the connection method between the control interface of each channel injection pump and the main controller;

[0032] In the diagram: 1-Multi-port solenoid valve, 2-Injection pump, 3-Reagent bottle, 4-Sample bottle, 5-Chromatography column, 6-Collection bottle, 7-Buffer tube, 8-T-connector, 9-First one-way valve, 10-Second one-way valve, 11-Switch valve; 101-First channel, 102-Second channel, 103-Third channel, 104-Fourth channel, 105-Fifth channel, 106-Sixth channel, 107-Seventh channel. Detailed Implementation

[0033] The present invention will now be further described with reference to specific embodiments and the accompanying drawings.

[0034] To address the shortcomings of existing instruments of the same type, this invention focuses on three aspects: control method, structural design, and process flow. It proposes a multi-channel fully automatic split-type solid-phase extraction instrument for separating actinide nuclides, based on precise control of liquid flow by an injection pump and independent collection of multi-step effluent.

[0035] The extractor includes a main controller, a human-machine interface, and multiple channel modules, each of which is independently controlled. Figure 1 A schematic diagram of the liquid circuit connection of a channel module is shown. Each channel module mainly includes a multi-way solenoid valve 1 and a syringe pump 2. The multi-way solenoid valve 1 has multiple channels, namely the first channel 101, the second channel 102, ... the Nth channel. The first channel 101 serves as a common channel and is connected to the syringe pump 2 of the corresponding channel module. The second channel 102 is connected to the inlet end of the sample bottle 4. The third channel 103 is connected to the inlet end of the chromatography column 5. The remaining channels are connected to multiple reagent bottles 3 respectively. The syringe pump 2 has a three-way valve head at the front end, which has a port a, a port b, and a port c. The port a is connected to the syringe pump. The ports b and c are connected to the air tube and the first channel of the multi-way solenoid valve 1, respectively. The inlet end of the chromatography column 5 is connected to a three-way valve 8. The two inlet ends of the three-way valve 8 are connected to the third channel of the multi-way solenoid valve 1 and the outlet end of the sample bottle 4, respectively. The collection bottle 6 is located directly below the chromatography column 5 and is used to collect the effluent from the chromatography column 5.

[0036] In terms of electrical control, each channel module is distinguished by a hardware address to achieve independent control. The hardware data control electrical interface adopts a bus-based control method, simplifying hardware connections and reducing control interfaces and cable connections in complex multi-hardware control environments. In terms of hardware, the main control components for each channel are a multi-port solenoid valve 1 and a syringe pump 2. All channels use different bus control interfaces for controlling the multi-port solenoid valve 1 and syringe pump 2. Communication cables for identical components in all channels are connected in parallel, and the two control groups for multi-port solenoid valve 1 and syringe pump 2 are sequentially set to different IDs using hardware addresses. This allows for simultaneous setting of multiple channels in hardware control while enabling the flexibility of independent control of each channel through different ID settings. Taking the syringe pump electrical interface as an example... Figure 2 This describes the connection method between the control interfaces of each channel's syringe pump and the main controller. Software control distinguishes between channels by their ID bytes in the communication protocol, enabling separate control of each independent channel. Different commands are used to control each channel when switching between the multi-port solenoid valve 1 and controlling the movement of syringe pump 2. Before the experiment, the operator sets the number of channels to be operated. Upon receiving this command, the main controller automatically determines the total number of channels to be operated in the experiment and assigns commands to the corresponding IDs of the channels to be operated for each experimental procedure. The problem of precise control of multi-channel solution column throughput can be solved by equalizing the length of tubing from different channels in the same step.

[0037] The extraction instrument consists of an electronic control cabinet for electronic control and an experimental cabinet for chemical operations. A multi-port solenoid valve 1, syringe pump 2, main controller, human-machine interface, and reagent bottles 3 are integrated in the electronic control cabinet. Sample solution bottles 4, chromatography columns 5, and collection bottles 6 are integrated in the experimental cabinet. The electronic control cabinet and the experimental cabinet are connected by pipes and cables. The length of the interconnecting pipes and cables can be adjusted according to the usage scenario for ease of use. The overall structure of the extraction instrument adopts a separate, compact design with two independent chassis, physically isolating important electronic components from the chemical pretreatment module. This minimizes the size and weight of individual instrument modules and effectively prevents sensitive electronic components from being damaged by acid fumes. It also facilitates the handling of high-activity samples in a glove box.

[0038] In this embodiment, the multi-port solenoid valve 1 has seven channels, with the fourth to seventh channels respectively connected to different reagent bottles.

[0039] In this embodiment, the highest point of the liquid level in the sample bottle 4 is lower than the lowest point of the chromatography column 5. This utilizes the principle of communicating vessels to ensure that the sample solution cannot flow through the chromatography column 5 on its own. Only when the gas pressure in the sample bottle is increased can the sample solution be forced through the resin column in the chromatography column 5. This design requires no expensive electronic components and, after the sample solution is installed, can fully automate the entire experimental process, including resin column pretreatment, feed loading, and solution washing of the resin column.

[0040] In this embodiment, a buffer tube 7 is provided on the pipeline connecting the first channel of the multi-way solenoid valve 1 and the syringe pump 2 to prevent reagents from flowing into the syringe pump 2 and thus affecting the accuracy and lifespan of the syringe pump 2. At the same time, it eliminates the problem of cross-contamination between reagents caused by the residue of solution in the rubber stopper of the syringe pump.

[0041] In this embodiment, a first one-way valve 9 is installed on the pipeline connecting the three-way valve 8 and the third channel of the multi-way solenoid valve 1, and a second one-way valve 10 is installed on the pipeline connecting the three-way valve and the outlet end of the sample bottle 4. These two one-way valves are used to ensure that when the sample solution in the pipeline flows into the chromatography column through one of the two inlet ends of the selected three-way valve 8, it cannot flow back to the multi-way solenoid valve 1 through the other inlet end of the three-way valve 8.

[0042] In this embodiment, a switch valve 11 is also provided at the outlet end of the sample bottle 4 to facilitate the control of the loading of the sample solution. Before use, the new sample bottle 4 and the switch valve 11 are connected but not installed on the instrument. The switch valve 11 is closed, the sample solution is added to the new sample bottle 4, and then this part is installed on the instrument and the switch valve 11 is opened.

[0043] In this embodiment, the sample bottle 4 is equipped with a sieve plate, which is a hydrophilic sieve plate with a pore size of <30μm.

[0044] In this embodiment, the number of reagent bottles 3 is two or more, and the number of reagent bottles 3 depends on the type of washing solution and elution solution required for the separation and purification process.

[0045] In this embodiment, the experimental cabinet also integrates a precision motor guide rail, on which a tray is fixed. Multiple collection bottles are installed in the tray to enable horizontal movement of the collection bottles. After each solution collection, the precision motor guide rail moves the tray horizontally a set distance, moving the new collection bottle directly below the chromatography column for easy collection of the next step's effluent. For the effluent flowing through the chromatography column in each step of the experiment, the precision motor guide rail controls the sequential movement of the collection bottles in the tray to the corresponding step, collecting the effluent from each step individually.

[0046] The experimental cabinet also integrates a Y-axis robotic arm and a longitudinal motor. The Y-axis robotic arm is connected to the chromatography column and is used to control the vertical movement of the column. Before each step, the Y-axis robotic arm lowers the outlet of the chromatography column below the collection bottle opening to prevent splashing of the effluent during discharge and cross-contamination between the instrument and the sample. After each column pass, the Y-axis robotic arm raises the chromatography column above the collection bottle opening. The surfaces of the robotic arm and motor are also coated with polytetrafluoroethylene (PTFE) to effectively prevent acid and alkali corrosion.

[0047] In this embodiment, the electrical control cabinet also integrates a precision gravity sensor, with each reagent bottle placed on the precision gravity sensor. Before each experiment begins, the precision gravity sensor compares the remaining reagent volume in the bottle with a set threshold. If the volume is lower than the set threshold, an alert is issued and the experiment is locked. The experiment is restarted only after the liquid addition is detected to be complete, thus avoiding experimental failure due to insufficient solution in the reagent bottle.

[0048] In this embodiment, the tubing from the sample bottle to the chromatography column uses a quick-connect fitting that can be easily replaced. Before each experiment, a new sample bottle, switch valve, second check valve, tee, chromatography column, collection bottle, and tubing in between need to be installed. The quick-connect fitting allows for easy replacement before each experiment, ensuring that each sample is replaced only once, thus completely eliminating the possibility of cross-contamination between samples from a physical structure perspective.

[0049] In this embodiment, multiple reagent bottles are externally mounted on the electrical control cabinet, and multiple sample liquid bottles are externally mounted on the experimental cabinet, making it convenient for experimental personnel to observe the liquid volume and replace the pipelines for reagents and liquids.

[0050] The instrument has specially reserved space inside to accommodate excess tubing, ensuring an aesthetically pleasing appearance. All tubing and wiring in the control cabinet and experimental cabinet are arranged using conduits / cable trays, and the control cabinet and experimental cabinet are directly connected via through-plate connectors, ensuring neat and clear wiring and facilitating future replacement of pipes and cables.

[0051] In operation, the desired reagent solution is selected via a multi-port solenoid valve, and the syringe pump precisely controls the reagent aspiration volume and flow rate through the chromatography column. When separating and purifying elements in the sample solution, the reagent is first drawn into a buffer tube connected to the syringe pump. Then, the multi-port solenoid valve selects the chromatography column channel, pushing the liquid in the buffer tube through the column and into the collection bottle. For sample solution passage, the sample bottle is connected to the syringe pump via the multi-port solenoid valve, directly pushing the air drawn in by the syringe pump into the sample bottle at a certain speed. The resulting positive pressure slowly forces the sample solution through the chromatography column at a controlled flow rate.

[0052] This invention provides a multi-channel fully automated split-type actinide solid-phase extraction instrument for separation. The instrument is rationally designed in three aspects: control method, structural design, and process flow. The control method employs a combination of a precision syringe pump and multi-channel solenoid valves to precisely control the type, volume, and column velocity of the sample solution and resin washing solution. A precision motor guide rail moves the position of the effluent receiving bottle, enabling independent collection of the effluent from each step of the multi-channel chromatography column. The overall structure adopts a split, compact design with two independent chassis, physically isolating important electronic components from the chemical pretreatment module. This minimizes the size and weight of individual instrument modules and effectively prevents damage to sensitive electronic components from acid fumes. It also facilitates the handling of high-activity samples in a glove box. The process flow features a rationally planned arrangement of multiple pipelines, resulting in a compact overall structure, clear pipeline routing, and easy installation and replacement. The independent design of the sample solution channel and washing solution channel allows for quick and convenient replacement of the pipelines and chromatography column through which the sample solution passes, significantly reducing the possibility of cross-contamination between different samples.

[0053] The above embodiments are merely illustrative examples of the present invention. The present invention may also be implemented in other specific ways or forms without departing from its spirit or essential characteristics. Therefore, the described embodiments should be considered illustrative rather than limiting in any respect. The scope of the present invention should be defined by the appended claims, and any variations equivalent to the intent and scope of the claims should also be included within the scope of the present invention.

Claims

1. A multi-channel fully automated split-type solid-phase extraction instrument for separating actinides, characterized in that, The extractor includes a main controller, a human-machine interface, and multiple channel modules. Each channel module includes a multi-port solenoid valve (1), a syringe pump (2), a chromatography column (5), multiple reagent bottles (3), a sample solution bottle (4), and multiple collection bottles (6), wherein: The multi-port solenoid valve (1) has multiple channels, namely the first channel, the second channel, ... the Nth channel. The first channel is connected to the injection pump (2) as a common channel, the second channel is connected to the inlet end of the sample bottle (4), the third channel is connected to the inlet end of the chromatography column (5), and the remaining channels are connected to the multiple reagent bottles (3) one by one. The injection pump (2) has a three-way valve head at the front end. The three-way valve head has port a, port b and port c. Port a is connected to the injection pump (2). Port b and port c are respectively connected to the air tube and the first channel of the multi-way solenoid valve (1). The inlet end of the chromatography column (5) is connected to a three-way valve, and the two inlet ends of the three-way valve (8) are respectively connected to the third channel of the multi-way solenoid valve (1) and the outlet end of the sample bottle (4); the collection bottle (6) is located below the chromatography column (5) and is used to collect the effluent from the chromatography column (5); The multi-port solenoid valve (1) and injection pump (2) of each channel module are connected to the main controller through different bus control interfaces. The communication cables of the same components of all channel modules are connected in parallel. The two control groups of multi-port solenoid valve (1) and injection pump (2) are set to different IDs in sequence through hardware addresses, so as to realize the method that all channel modules can be controlled as a whole and individual channel modules can be controlled separately.

2. The multi-channel fully automated split-type actinide solid-phase extraction instrument for separation according to claim 1, characterized in that, The extraction instrument includes an electrical control cabinet and an experimental cabinet. The multi-port solenoid valve (1), injection pump (2), main controller, human-machine interface, and reagent bottle (3) are integrated in the electrical control cabinet. The chromatography column (5), sample bottle (4), and collection bottle (6) are integrated in the experimental cabinet. The electrical control cabinet and the experimental cabinet are connected by pipelines and cables.

3. The multi-channel fully automated split-type actinide solid-phase extraction instrument for separation according to claim 2, characterized in that, The corresponding pipe lengths in each channel module are equal to ensure the accuracy of the multi-channel solution flow volume.

4. The multi-channel fully automated split-type actinide separation solid-phase extraction instrument according to any one of claims 1-3, characterized in that, The highest point of the liquid level in the sample bottle (4) is lower than the lowest point of the chromatography column (5) to ensure that the sample solution cannot flow through the chromatography column on its own.

5. The multi-channel fully automated split-type actinide solid-phase extraction instrument for separation according to claim 4, characterized in that, A buffer tube (7) is provided on the pipeline connecting the first channel of the multi-way solenoid valve (1) and the injection pump (2) to prevent reagents from flowing into the injection pump (2) and thus affecting its accuracy and lifespan, while also avoiding cross-contamination between reagents.

6. The multi-channel fully automated split-type actinide solid-phase extraction instrument for separation according to claim 5, characterized in that, A first one-way valve (9) is installed on the pipeline connecting the three-way valve (8) and the third channel of the multi-way solenoid valve (1), and a second one-way valve (10) is installed on the pipeline connecting the three-way valve (8) and the outlet end of the sample bottle (4).

7. The multi-channel fully automated split-type actinide solid-phase extraction instrument for separation according to claim 6, characterized in that, A switching valve (11) is provided on the pipeline between the outlet end of the sample bottle (4) and the second one-way valve (10) to facilitate the control of the loading of the sample solution.

8. The multi-channel fully automated split-type actinide solid-phase extraction instrument for separation according to claim 7, characterized in that, The sample bottle (4) is equipped with a sieve plate, which is a hydrophilic sieve plate with a pore size of <30μm.

9. The multi-channel fully automated split-type actinide solid-phase extraction instrument for separation according to claim 8, characterized in that, The experimental cabinet also integrates a precision motor guide rail, on which a tray is fixed. Multiple collection bottles (6) are installed in the tray. The precision motor guide rail can sequentially move the collection bottles (6) in the tray horizontally to directly below the chromatography column (5) to collect the effluent from each step individually. The experimental cabinet also integrates a Y-axis robotic arm and a longitudinal motor. The Y-axis robotic arm is connected to the chromatography column (5) and is used to control the vertical movement of the chromatography column (5). The longitudinal motor can control the Y-axis robotic arm to drive the outlet of the chromatography column (5) down to below the mouth of the collection bottle to prevent the effluent from splashing during discharge and causing cross-contamination between the instrument and the sample.

10. The multi-channel fully automated split-type actinide solid-phase extraction instrument according to claim 9, characterized in that, The electrical control cabinet also integrates a precision gravity sensor. Each reagent bottle (3) is placed on the precision gravity sensor to compare the remaining capacity of the reagent in the reagent bottle (3) with a set threshold. If it is lower than the set threshold, a reminder is given and the experimental process is locked.

11. The multi-channel fully automated split-type actinide solid-phase extraction instrument for separation according to claim 10, characterized in that, The tubing from the sample bottle (4) to the chromatography column (5) uses a quick-connect fitting that allows for easy replacement.

12. The multi-channel fully automated split-type actinide solid-phase extraction instrument according to any one of claims 5-11, characterized in that, The reagent bottle (3) is externally mounted on the electrical control cabinet, and the sample liquid bottle (4) is externally mounted on the experimental cabinet.

Images