Antimicrobial peptide recovery device

Abstract

The present invention relates to the field of bio-fermentation technology, and specifically to an antimicrobial peptide recovery device, comprising: a filter box; a ceramic membrane filter; a spray mechanism, wherein the spray mechanism is arranged outside the ceramic membrane filter and connected to the filter box; an evaporation recovery mechanism, wherein the evaporation recovery mechanism is connected to the filter box and the spray mechanism; wherein the evaporation recovery mechanism comprises: a water delivery component, wherein the water delivery component is connected to the filter box and the spray mechanism; and an evaporation component, wherein the evaporation component is connected to the water delivery component and the filter box. By arranging the spray mechanism and the evaporation recovery mechanism, not only can the spray mechanism be driven to flush away antimicrobial peptides adsorbed on the ceramic membrane filter, but also the membrane flushing water can be absorbed and the absorbed membrane flushing water can be evaporated to obtain antimicrobial peptides. The device is easy to operate, and recovery is time-saving, labor-saving, and resource-saving.

Description

Technical Field

[0001] The invention relates to the technical field of biological fermentation, in particular to an antimicrobial peptide recovery device. Background Art

[0002] Antimicrobial peptides are small, biologically active peptides induced in vivo. Most of these peptides possess strong alkalinity, thermal stability, and broad-spectrum antimicrobial properties. They have a potent antibacterial effect on bacteria, particularly against certain drug-resistant pathogens. Furthermore, certain antimicrobial peptides have been found to kill viruses, fungi, protozoa, and cancer cells, and can even enhance immunity and accelerate wound healing. The broad range of biological activities of antimicrobial peptides suggests promising medical applications, with significant potential.

[0003] Currently, most tools for extracting antimicrobial peptides are not rinsed thoroughly, resulting in blockage and residue, while thorough rinsing easily leads to waste. It is difficult to achieve both. Therefore, in view of the above situation, there is an urgent need to develop an antimicrobial peptide recovery device to overcome the shortcomings in current practical applications. Summary of the Invention

[0004] The object of the present invention is to provide an antimicrobial peptide recovery device to solve the problems raised in the above background technology.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] An antimicrobial peptide recovery device, comprising:

[0007] A filter box, with a water inlet pipe and a drain pipe fixedly connected to both sides of the filter box;

[0008] A ceramic membrane filter, the ceramic membrane filter being arranged inside the filter box;

[0009] A spray mechanism, which is arranged outside the ceramic membrane filter and connected to the filter box, and is used to flush away the antimicrobial peptides adsorbed on the ceramic membrane filter;

[0010] An evaporation recovery mechanism, connected to the filter box and the spray mechanism, for evaporating membrane flushing water to obtain antimicrobial peptides;

[0011] Wherein, the evaporation recovery mechanism includes:

[0012] A water delivery component, connected to the filter box and the spray mechanism, for driving the spray mechanism to clean the antimicrobial peptides adsorbed on the ceramic membrane filter;

[0013] The evaporation component is connected to the water delivery component and the filter box, and is used to absorb and evaporate the membrane flushing water.

[0014] Compared with the prior art, the present invention has the following beneficial effects:

[0015] When the device is running, after the antimicrobial peptide fermentation liquid is filtered, the water delivery component delivers spray water into the inner side of the spray mechanism. The spray mechanism can not only complete the flushing of the ceramic membrane filter, but also the water delivery component will drive the spray mechanism to swing back and forth, thereby ensuring the comprehensiveness of the flushing, and the evaporation component absorbs the flushing membrane water and evaporates the absorbed flushing membrane water. The evaporated flushing membrane water is dried to a water content of less than % to obtain antimicrobial peptides. Compared with the existing technology, most of the tools for extracting antimicrobial peptides are not thoroughly flushed, resulting in blockage and residue, and thorough flushing is likely to cause waste. It is difficult to achieve both. By setting up a spray mechanism and an evaporation recovery mechanism, not only can the spray mechanism be driven to flush away the antimicrobial peptides adsorbed on the ceramic membrane filter, but also the flushing membrane water can be absorbed and evaporated to obtain antimicrobial peptides. The operation is convenient, the recovery is time-saving and labor-saving, and resources are saved. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 Schematic diagram of the structure of the antimicrobial peptide recovery device.

[0017] Figure 2 A top view of the flushing components in the antimicrobial peptide recovery device.

[0018] Figure 3 This is a schematic diagram of the structure of the transmission box in the antimicrobial peptide recovery device.

[0019] Figure 4 Schematic diagram of the structure of the regulating frame in the antimicrobial peptide recovery device.

[0020] In the figure: 1-filter box, 2-water inlet pipe, 3-drain pipe, 4-ceramic membrane filter, 5-first water pump, 6-water suction pipe, 7-water guide pipe, 8-connecting box, 9-evaporation box, 10-heating plate, 11-pressure relief pipe, 12-water storage tank, 13-transmission box, 14-infusion pipe, 15-connecting pipe, 16-transmission rod, 17-first gear, 18-threaded rod, 19-slide plate, 20-second gear, 21-first rack, 22-support pipe, 23-third gear, 24-spray pipe, 25-fan blade, 26-water outlet pipe, 27-adjustment frame, 28-second rack, 29-limit block, 30-third rack. DETAILED DESCRIPTION

[0021] The technical solution of this patent is further described in detail below in conjunction with specific implementation methods.

[0022] The following describes in detail embodiments of the present invention, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.

[0023] See also Figure 1 In one embodiment of the present invention, an antimicrobial peptide recovery device includes: a filter box 1, wherein a water inlet pipe 2 and a drain pipe 3 are fixedly connected on both sides of the filter box 1; a ceramic membrane filter 4, wherein the ceramic membrane filter 4 is arranged on the inner side of the filter box 1; a spray mechanism, wherein the spray mechanism is arranged on the outer side of the ceramic membrane filter 4 and is connected to the filter box 1, and is used to flush away the antimicrobial peptides adsorbed on the ceramic membrane filter 4; an evaporation recovery mechanism, wherein the evaporation recovery mechanism is connected to the filter box 1 and the spray mechanism, and is used to evaporate the membrane flushing water to obtain the antimicrobial peptides; wherein the evaporation recovery mechanism includes: a water delivery component, wherein the water delivery component is connected to the filter box 1 and the spray mechanism, and is used to drive the spray mechanism to clean the antimicrobial peptides adsorbed on the ceramic membrane filter 4; and an evaporation component, wherein the evaporation component is connected to the water delivery component and the filter box 2, and is used to absorb and evaporate the membrane flushing water.

[0024] In this embodiment, when the device is running, after the antimicrobial peptide fermentation liquid is filtered, the water delivery component delivers spray water into the inner side of the spray mechanism. The spray mechanism can not only complete the flushing of the ceramic membrane filter 4, but also the water delivery component will drive the spray mechanism to swing back and forth, thereby ensuring the comprehensiveness of the flushing, and the evaporation component absorbs the flushing membrane water and evaporates the absorbed flushing membrane water. The evaporated flushing membrane water is dried to a water content of less than 8% to obtain antimicrobial peptides. Compared with the existing technology, most of the tools for extracting antimicrobial peptides are not thoroughly flushed, resulting in blockage and residue. Thorough flushing easily causes waste, and it is difficult to achieve both. By setting up a spray mechanism and an evaporation recovery mechanism, not only can the spray mechanism be driven to flush away the antimicrobial peptides adsorbed on the ceramic membrane filter 4, but the flushing membrane water can also be absorbed and evaporated to obtain antimicrobial peptides. The operation is convenient, the recovery is time-saving and labor-saving, and resources are saved.

[0025] In one embodiment of the present invention, the water delivery component includes: a connecting box 8, which is fixedly connected to the filter box 2; a water storage tank 12, which is fixedly connected to the inner side of the connecting box 8 and is provided with a second water pump inside; a transmission component, which is provided between the second water pump and the spray mechanism and is connected to the connecting box 8 for realizing water delivery; a connecting component, which is provided between the transmission component and the spray mechanism and is used to cooperate with the transmission component to drive the spray mechanism to rotate.

[0026] In this embodiment, the connecting box 8 is fixedly connected to the outside of the filter box 1. By setting a water delivery component, the second water pump drives water along the transmission component into the inside of the spray mechanism. During the flow of water inside the transmission component, on the one hand, it drives the connecting component, and the connecting component can drive the spray mechanism to rotate, thereby improving the comprehensiveness of flushing. On the other hand, it can cooperate with the evaporation component to accelerate the evaporation efficiency.

[0027] In one embodiment of the present invention, please refer to Figure 1 and Figure 3 The transmission assembly includes: a transmission box 13, which is fixedly connected to the connecting box 8 and is connected to the output end of the second water pump through a liquid infusion pipe 14; a water outlet pipe 26, which is arranged between the transmission box 13 and the spray mechanism to realize water transportation; a transmission rod 16, which is rotatably connected to the transmission box 13, fixedly connected to the fan blade 25 arranged on the inner side of the transmission box 13, and connected to the evaporation component; a first gear 17, which is arranged between the connecting assembly and the transmission rod 16, fixedly connected to the transmission rod 16, and is used to cooperate with the transmission rod 16 to drive the connecting assembly to realize the rotation of the spray mechanism.

[0028] In this embodiment, the water outlet pipe 26 is fixedly connected to the top of the transmission box 13, and the connection between the infusion pipe 14 and the transmission box 13 is located on the side wall of the transmission box 13, and is arranged at an oblique angle to the transmission rod 16. The first gear 17 is provided on the outside of the transmission rod 16 close to one end of the connecting assembly and is connected to the connecting assembly. The first gear 17 is a half gear. By setting up the transmission assembly, water enters the inside of the transmission box 13 along the infusion pipe 14 under the action of the second water pump, and enters the inside of the spray mechanism through the water outlet pipe 26. In the process of flowing inside the transmission box 13, the water cooperates with the fan blades 25 to drive the transmission rod 16 to rotate. The transmission rod 16 uses the first gear 17 to drive the connecting assembly. The transmission rod 16 is also connected to the stirring rod inside the evaporation assembly, which can drive the stirring rod to rotate, thereby accelerating the evaporation of the flushing membrane water.

[0029] In one embodiment of the present invention, please refer to Figure 1 and Figure 4The connecting component includes: an adjusting frame 27, which is arranged on the outside of the first gear 17 and is slidably connected to the connecting box 8; a third rack 30, which is symmetrically arranged on both sides of the first gear 17, meshed with the first gear 17, and fixedly connected to the adjusting frame 27, and is used to cooperate with the first gear 17 to drive the adjusting frame 27 to reciprocate; a second rack 28, which is fixedly connected to the outside of the adjusting frame 27 and is connected to the spray mechanism, and is used to cooperate with the movement of the adjusting frame 27 to drive the spray mechanism to rotate.

[0030] In this embodiment, limit blocks 29 are fixedly connected on both sides of the adjustment frame 27, and the limit blocks 29 are slidably connected to the box wall of the connecting box 8. By setting a connecting component, the first gear 17 cooperates with the third racks 30 on both sides to realize the reciprocating operation of the adjustment frame 27. The adjustment frame 27 cooperates with the second gear 20 set on the inner side of the spray mechanism through the second rack 28 to realize the reciprocating swing of the spray mechanism, which is beneficial to the comprehensiveness of the flushing of the lifting device.

[0031] In one embodiment of the present invention, the evaporation component includes: an evaporation box 9, which is fixedly connected to the inner side of the connection box 8; a heating plate 10, which is fixedly connected to the inner side of the evaporation box 9, and is used to realize the evaporation of the flushing membrane water; a first water pump 5, which is fixedly connected to the filter box 1, and the input end is connected to the filter box 1 through a water suction pipe 6, and the output end is connected to the evaporation box 9 through an air guide pipe 7, and is used to realize the diversion of the flushing membrane water; a stirring rod, which is rotatably connected to the inner side of the evaporation box 9 and is connected to the transmission assembly, and is used to cooperate with the transmission assembly to realize the stirring of the flushing membrane water.

[0032] In this embodiment, the heating plate 10 is fixedly connected to the bottom inner side of the evaporation box 9, one end of the water guide pipe 7 is connected to the output end of the first water pump 5, and the other end is connected to the top of the side wall of the evaporation box 9. In addition, a pressure relief pipe 11 is fixedly connected to the top of the evaporation box 9, wherein the pressure relief pipe 11, the water suction pipe 6 and the inner side of the water guide pipe 7 are fixedly connected with a valve, and the stirring rod is provided inside the evaporation box 9, and is rotatably connected to the box wall of the evaporation box 9, and is connected to the transmission rod 16 through a bevel gear. By setting up an evaporation component, the first water pump 5 uses the water suction pipe 6 to extract the flushing membrane water located inside the filter box 1, and uses the water guide pipe 7 to send it to the inside of the evaporation box 9. The heating plate 10 heats the flushing membrane water located inside the evaporation box 9, and the stirring rod stirs the flushing membrane water under the drive of the transmission rod 16, thereby accelerating the evaporation efficiency. The flushing membrane water after evaporation is dried to a water content of less than 8% to obtain antimicrobial peptides.

[0033] In one embodiment of the present invention, the spray mechanism includes: a support tube 22, which is rotatably connected to the inner side of the filter box 2; a connecting tube 15, which is arranged between the support tube 22 and the transmission assembly, and one end of which is connected to the inner side of the support tube 22; a third gear 23, which is fixedly connected to the support tube 22; a spray pipe 24, which is fixedly connected to the outer side of the support tube 22, and is used to cooperate with the water supply assembly to flush the ceramic membrane filter 4; an adjusting assembly, which is arranged between the third gear 23 and the connecting assembly, and is used to cooperate with the connecting assembly to drive the support tube 22 to rotate.

[0034] In this embodiment, the support tube 22 is rotatably connected to the connecting seat fixedly connected to the box wall at both ends of the inner side of the filter box 2, and a sealing ring is fixedly connected to the outer side of the tube wall at the connection between the support tube 22 and the connecting seat. A third gear 23 is fixedly connected to the outer side of the two ends of the support tube 22, and a number of spray pipes 24 fixedly connected to the support tube 22 are provided between the second gears 23 on both sides. A connecting pipe 15 is provided on the inside of the support tube 22, and the other end of the connecting pipe 15 passes through the box wall of the filter box 1 and is connected to the water outlet pipe 26 of the transmission assembly. By setting up a spray mechanism, the connecting assembly will drive the adjusting assembly, and the adjusting assembly and the third gear 23 can realize the reciprocating swing of the support tube 22. After the water is discharged from the water outlet pipe 26, it enters the inner side of the support tube 22 along the connecting pipe 15 and is discharged from the spray pipe 24, which can wash away the antimicrobial peptides adsorbed on the ceramic membrane filter 4, and as the support tube 22 rotates, the comprehensiveness of the cleaning is guaranteed.

[0035] In one embodiment of the present invention, please refer to Figure 1 and Figure 2 The adjusting assembly includes: a slide 19, which is arranged on the outside of the support tube 22 and is slidingly connected to the filter box 1; a threaded rod 18, which is threadedly connected to the slide 19, rotatably connected to the filter box 1, and is connected to the connecting assembly through a second gear 20, and is used to cooperate with the connecting assembly to drive the slide 19 to reciprocate along the wall of the filter box 1; a first rack 21, which is meshingly connected and arranged on the outside of the third gear 23, and is fixedly connected to the slide 19, and is used to cooperate with the slide 19 to drive the support tube 22 to rotate.

[0036] In this embodiment, the third gear 23 is meshed with the second rack 28, and the first rack 21 is provided on both sides of the threaded rod 18, and is respectively meshed with the third gear 23 on both sides. By setting an adjustment component, when the adjustment frame 27 moves, the second rack 28 provided on the outside of the adjustment frame 27 cooperates with the second gear 20 to drive the threaded rod 18 to rotate alternately clockwise and counterclockwise, and the threaded rod 18 drives the slide 19 to reciprocate, and the first rack 21 on the outside of the slide 19 cooperates with the third gear 23 to drive the support tube 22 to swing back and forth, thereby ensuring the comprehensiveness of the device in cleaning the ceramic membrane filter 4.

[0037] The antimicrobial peptide recovery device, by providing a spray mechanism and an evaporation recovery mechanism, can not only drive the spray mechanism to flush away antimicrobial peptides adsorbed on the ceramic membrane filter 4, but also absorb the membrane flushing water and evaporate the absorbed membrane flushing water to obtain antimicrobial peptides. The device is easy to operate, saves time and effort, and conserves resources. By providing a water delivery component, a second water pump drives water along the transmission component into the inside of the spray mechanism. During the process of water flowing inside the transmission component, it drives the connecting component, which can drive the spray mechanism to rotate, thereby improving the comprehensiveness of flushing. On the other hand, it can cooperate with the evaporation component to accelerate evaporation efficiency. By providing the spray mechanism, the connecting component will drive the adjusting component, which cooperates with the third gear 23 to achieve reciprocating swing of the support tube 22. After being discharged from the water outlet pipe 26, the water enters the inside of the support tube 22 along the connecting pipe 15 and is discharged from the spray pipe 24, which can flush away the antimicrobial peptides adsorbed on the ceramic membrane filter 4. As the support tube 22 rotates, comprehensive cleaning is ensured.

[0038] The above are only preferred embodiments of the present invention. It should be pointed out that for those skilled in the art, several modifications and improvements can be made without departing from the concept of the present invention. These should also be regarded as the scope of protection of the present invention. These will not affect the effect of the implementation of the present invention and the practicality of the patent.

Claims

1. An antimicrobial peptide recovery device, characterized in that ,include: A filter box (1), wherein a water inlet pipe (2) and a drain pipe (3) are fixedly connected to both sides of the filter box (1); A ceramic membrane filter (4), the ceramic membrane filter (4) being arranged inside the filter box (1); a spray mechanism, the spray mechanism being arranged outside the ceramic membrane filter (4), connected to the filter box (1), and being used to flush away antimicrobial peptides adsorbed on the ceramic membrane filter (4); An evaporation recovery mechanism, the evaporation recovery mechanism is connected to the filter box (1) and the spray mechanism, and is used for evaporating and flushing membrane water to obtain antimicrobial peptides; Wherein, the evaporation recovery mechanism includes: A water delivery component, the water delivery component being connected to the filter box (1) and to the spray mechanism, and being used to drive the spray mechanism to clean the antimicrobial peptides adsorbed on the ceramic membrane filter (4); An evaporation component, the evaporation component is connected to the water delivery component and to the filter box (1), and is used to achieve absorption and evaporation of membrane flushing water; The water delivery assembly includes a transmission assembly, and the transmission assembly includes a transmission rod (16) fixedly connected to a fan blade (25) arranged inside a transmission box (13); The evaporation component comprises a stirring rod, which is used to cooperate with the transmission component to achieve stirring of the membrane flushing water; the stirring rod is rotatably connected to the inside of the evaporation box (9) and is connected to the transmission component.

2. The antimicrobial peptide recovery device according to claim 1, characterized in that , the water delivery component includes: A connecting box (8) is fixedly connected to the filter box (1); the transmission assembly is provided between the second water pump and the spray mechanism, and is connected to the connecting box (8) for transporting water; the connecting assembly is provided between the transmission assembly and the spray mechanism, and is used to cooperate with the transmission assembly to drive the spray mechanism to rotate; A water storage tank (12) is fixedly connected to the inner side of the connection box (8), and a second water pump is provided on the inner side.

3. The antimicrobial peptide recovery device according to claim 2, characterized in that: The transmission assembly comprises: A transmission box (13), the transmission box (13) is fixedly connected to the connection box (8) and is connected to the output end of the second water pump through a liquid infusion tube (14); the transmission rod (16) is rotatably connected to the transmission box (13) and is connected to the evaporation component A water outlet pipe (26), the water outlet pipe (26) is provided between the transmission box (13) and the spray mechanism, and is used to realize water transportation; A first gear (17) is provided between the connecting assembly and the transmission rod (16), is fixedly connected to the transmission rod (16), and is used to cooperate with the transmission rod (16) to drive the connecting assembly to realize the rotation of the spray mechanism.

4. The antimicrobial peptide recovery device according to claim 3, characterized in that , the connection component includes: an adjustment frame (27), the adjustment frame (27) being arranged outside the first gear (17) and being slidably connected to the connection box (8); a third rack (30), the third rack (30) being symmetrically arranged on both sides of the first gear (17), being meshed and connected with the first gear (17), and being fixedly connected with the adjustment frame (27), and being used to cooperate with the first gear (17) to drive the adjustment frame (27) to reciprocate; A second rack (28) is fixedly connected to the outside of the adjustment frame (27) and is connected to the spray mechanism, and is used to drive the spray mechanism to rotate in conjunction with the movement of the adjustment frame (27).

5. The antimicrobial peptide recovery device according to claim 4, characterized in that: The evaporation assembly comprises: an evaporation box (9), the evaporation box (9) being fixedly connected to the inner side of the connection box (8); A heating plate (10), the heating plate (10) is fixedly connected to the inner side of the evaporation box (9) and is used to evaporate the membrane flushing water; A first water pump (5) is fixedly connected to the filter box (1), and its input end is connected to the filter box (1) via a water pumping pipe (6), and its output end is connected to the evaporation box (9) via an air guide pipe (7), for achieving the diversion of membrane flushing water.

6. The antimicrobial peptide recovery device according to claim 2, characterized in that , the spraying mechanism includes: A support tube (22), the support tube (22) being rotatably connected and arranged inside the filter box (1); A connecting pipe (15), the connecting pipe (15) being arranged between the supporting pipe (22) and the transmission assembly, and having one end extending to the inner side of the supporting pipe (22); a third gear (23), the third gear (23) being fixedly connected to the support tube (22); A spray pipe (24), the spray pipe (24) being fixedly connected to the outside of the support pipe (22) and used to cooperate with the water delivery assembly to flush the ceramic membrane filter; An adjusting component is provided between the third gear (23) and the connecting component, and is used to cooperate with the connecting component to drive the support tube (22) to rotate.

7. The antimicrobial peptide recovery device according to claim 6, characterized in that , the adjustment component includes: A slide plate (19), the slide plate (19) being arranged outside the support tube (22) and being slidably connected to the filter box (1); a threaded rod (18), the threaded rod (18) being threadedly connected to the slide plate (19), being rotationally connected to the filter box (1), and being connected to the connecting assembly via a second gear (20), and being used to cooperate with the connecting assembly to drive the slide plate (19) to reciprocate along the wall of the filter box (1); A first rack (21) is meshingly connected and disposed outside the third gear (23), and is fixedly connected to the slide plate (19), and is used to cooperate with the slide plate (19) to drive the support tube (22) to rotate.

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