Anti-loosening high-integrity centrifuge tube and method of use

By incorporating an anti-detachment cavity and a fixing frame within the centrifuge tube, and utilizing the water-swellable body to generate support during centrifugation, the problem of loose connection between the tube body and the cap is solved, achieving a centrifuge tube design with high stability and sealing.

CN116135314BActive Publication Date: 2025-11-18ZHEJIANG SAINING BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202111368780.1
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-11-18
Publication Date
2025-11-18
Estimated Expiration
2041-11-18

AI Technical Summary

Technical Problem

The connection between the tube body and cap of existing centrifuge tubes is unstable and prone to loosening, affecting sealing and experimental results.

Method used

An anti-detachment cavity and a fixing frame are set inside the cap of the centrifuge tube. The expansion of the water-swellable body during centrifugation creates a supporting force. Combined with the axial fixing structure and one-way valve mechanism, the tight connection between the cap and the tube body is ensured.

Benefits of technology

This improves the overall stability and sealing of centrifuge tubes, prevents loosening, and ensures the accuracy and reliability of experimental results.

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Abstract

The application discloses a kind of anti-loosening high integrity centrifugal tube and its use method, to provide a kind of anti-loosening effect is good, integrity is strong and practicality strong centrifugal tube and its use method, its technical scheme main points are by being provided with anti-disengagement cavity in cover body, and the fixed frame being set in anti-disengagement cavity and being axially movably connected with anti-disengagement cavity as carrier, and first slot being set on fixed frame and being towards cover body inside, second slot being set on fixed frame and being towards pipe body side, again by first water-swelling body being set in first slot and second water-swelling body being set in second slot, so that when centrifugal tube is carried out centrifugation operation, the water-swelling of first, second water-swelling body is formed by the shock, second water-swelling body forms acting force expansion support between cover body and bottle body after water-swelling, so that the thread between cover body and bottle body is mutually locked, the application is applicable to medical equipment technical field.
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Description

Technical Field

[0001] This invention relates to the field of medical device technology, and more specifically, to a high-integrity, anti-loosening centrifuge tube and its method of use. Background Technology

[0002] Centrifuge tubes are now widely used, especially in life sciences, such as biochemistry, molecular biology, cell biology, and microbiology.

[0003] Centrifuge tubes are widely used in education, teaching, and scientific experiments for sample preservation, chemical reactions, biological extraction and separation, strain preservation, cell and microbial culture, and genetic material amplification.

[0004] Centrifuge tubes are also widely used in hospitals for the preservation and analysis of biological and chemical samples.

[0005] Currently, centrifuge tubes on the market consist of a tube body and a cap that is detachably connected to the tube body. Traditional centrifuge tube structures have poor connection stability between the tube body and the cap, making them prone to leaks and compromised seals under the high-speed rotation of the centrifuge. This results in poor practicality and can even affect subsequent experiments. Summary of the Invention

[0006] In view of the shortcomings of the existing technology, the purpose of this invention is to provide a centrifuge tube with good anti-loosening effect, strong integrity and practicality, and a method for using it.

[0007] To achieve the above objectives, the present invention provides the following technical solution: a centrifuge tube with high integrity and anti-loosening properties, comprising a tube body and a cover detachably connected to the tube body, an anti-detachment cavity within the cover body, a fixing frame disposed within the anti-detachment cavity and axially movably connected to the anti-detachment cavity, a first groove disposed on the fixing frame and facing the inner side of the cover body, a second groove disposed on the fixing frame and facing one side of the tube body, a first water-swellable body disposed in the first groove, and a second water-swellable body disposed in the second groove, wherein the second water-swellable body abuts against the end face of the tube body after expanding upon contact with water, and the fixing frame is provided with a connecting hole communicating with the first groove.

[0008] The present invention is further configured such that: an axial fixing structure is provided between the fixing frame and the anti-detachment cavity, the axial fixing structure including a fixing rod disposed in the anti-detachment cavity and penetrating the fixing frame, and a limiting structure for limiting the fixing frame.

[0009] The present invention is further configured such that the limiting structure includes a threaded blind hole disposed on the fixed rod and a screw detachably connected to the threaded blind hole.

[0010] The present invention is further configured such that: the anti-detachment cavity is provided with a water storage part, the water storage part includes a water storage cavity, a water outlet hole provided on the inner wall of the water storage cavity, and a one-way valve structure provided in the water outlet hole. The one-way valve structure is configured to be in an open state when the centrifuge tube is rotating and in a closed state when the centrifuge tube is stationary. The cover is provided with a water injection hole communicating with the water storage cavity.

[0011] The present invention is further configured such that: the one-way valve structure includes an installation channel disposed on the end face of the water outlet and extending toward the inner wall of the water storage chamber, a tightening section disposed in the installation channel, a valve ball disposed at the tightening section, an installation ring groove disposed at the outer end of the installation channel, a retaining spring disposed in the installation ring groove, and a spring having one end abutting against the retaining spring and the other end abutting against the valve ball.

[0012] The invention is further configured such that the outer diameter of the tightening section gradually decreases from outside the water storage chamber towards inside the chamber.

[0013] The invention is further configured such that: an abutment pad is provided between the end face of the second water-swellable body and the tube body, and the abutment pad is made of ordinary rubber material.

[0014] The present invention is further configured such that the first water-swellable body and the second water-swellable body are made of water-absorbing resin or water-swellable rubber.

[0015] By adopting the above technical solution, the following beneficial effects are achieved: 1. By setting an anti-detachment cavity in the cap body and using a fixed frame set in the anti-detachment cavity and axially movably connected to the anti-detachment cavity as a carrier, and a first groove set on the fixed frame facing the inner side of the cap body and a second groove set on the fixed frame facing the tube body, and by using a first water-swellable body set in the first groove and a second water-swellable body set in the second groove, the turbulence generated during the centrifugation operation of the centrifuge tube causes the first water-swellable body and the second water-swellable body to expand upon contact with water. After the second water-swellable body expands upon contact with water, it forms an expansion support force between the cap body and the bottle body, causing the threads between the cap body and the bottle body to interlock, thereby improving the overall anti-detachment effect, with strong stability and simple structure. Furthermore, by providing a connecting hole on the fixed frame that communicates with the first groove, the connecting hole structure can also cause the first water-swellable body in the first groove to expand upon contact with water, thereby forming a bidirectional expansion support effect and providing an overall interlocking effect of the threads.

[0016] 2. To ensure the fixation effect of the fixed frame, an axial fixing structure is provided between the fixed frame and the anti-detachment cavity. The axial fixing structure includes a fixing rod set in the anti-detachment cavity and passing through the fixed frame, and a limiting structure for limiting the fixed frame. The limiting structure includes a threaded blind hole set in the fixing rod and a screw detachably connected to the threaded blind hole. The fixed frame is limited by the fixing rod and the limiting structure, while the cooperation of the screw and the threaded blind hole achieves the effect of easy disassembly. The structure is simple and highly practical.

[0017] 3. To improve the overall expansion effect, a water storage section is provided within the anti-detachment cavity. This water storage section includes a water storage chamber, a water outlet on the inner wall of the water storage chamber, and a one-way valve structure within the water outlet. When the centrifuge tube is rotating, the one-way valve is in the open state; when the centrifuge tube is stationary, the one-way valve is in the closed state. This ensures a strong expansion support effect during high-speed centrifugal motion, thereby improving the overall anti-detachment effect, providing high stability, and a simple structure. Furthermore, a water injection hole on the cover, communicating with the water storage chamber, facilitates the addition of water for future use.

[0018] 4. Further, the one-way valve structure is configured to include an installation channel located on the end face of the water outlet and extending into the inner wall of the water storage chamber, a tightening section located within the installation channel, a valve ball located at the tightening section, an installation ring groove located at the outer end of the installation channel, a retaining ring located within the installation ring groove, and a spring with one end in contact with the retaining ring and the other end in contact with the valve ball. Through the installation channel structure and the cooperation of the spring and valve ball, the spring acts as a support for the valve ball, forming a blockage at the water outlet. When the centrifuge tube is in centrifugal motion, the valve ball moves outward, thereby opening the water outlet, increasing the expansion degree of the water-swellable body in the anti-detachment cavity, and improving the overall anti-detachment effect.

[0019] A method for using the above-mentioned anti-loosening high-integration centrifuge tube includes the following steps: S1, open the water injection hole on the cover, add water into the water storage chamber, and tighten the cover;

[0020] S2. Place the centrifuge tubes into the centrifuge and turn on the centrifuge to perform the centrifugation operation;

[0021] S3. As the centrifuge speed gradually increases, the valve ball in the water storage chamber inside the centrifuge tube pushes open the spring under centrifugal force. At this time, the water in the water storage chamber is thrown out and enters the anti-detachment chamber.

[0022] S4. The first water-swellable body in the anti-detachment cavity expands continuously after encountering water and compresses the fixing frame.

[0023] S5. At the same time, when the centrifuge tube is centrifuged, the second water-swellable body will also expand when it comes into contact with water and squeeze the cap, and the threads of the cap and the bottle will form an interlocking state.

[0024] S6. As the amount of water thrown out of the water storage chamber gradually increases, the expansion amount of the first water-swellable body is greater than that of the second water-swellable body. At this time, the fixing frame bends towards the inside of the bottle and seals the bottle mouth.

[0025] S7. Continue until the centrifugation operation is completed. After the centrifugation operation is completed, remove the failed first and second water-swellable bodies through the inlet and replace them for future use.

[0026] By adopting the above technical solution, beneficial effects are achieved. By using the water-swellable body as the expansion carrier, the water in the storage chamber as the expansion source, and the centrifugal motion of the centrifuge as the trigger condition, the one-way valve opens under the centrifugal motion, thus creating a water discharge effect. This causes the first water-swellable body to fully expand upon contact with water and compresses the cap. The threads of the cap and the bottle body will form an interlocking state. The expansion amount of the first water-swellable body is greater than that of the second water-swellable body. At this time, the fixing frame bends towards the inside of the bottle and seals the bottle mouth, greatly improving the anti-detachment effect. The structure is simple and highly practical. Attached Figure Description

[0027] Figure 1 This is a partial cross-sectional view of an embodiment of the anti-loosening, high-integrity centrifuge tube and its usage method according to the present invention.

[0028] Figure 2 This invention relates to an anti-loosening, high-integrity centrifuge tube and its usage method. Figure 1 Enlarged schematic diagram of the central structure.

[0029] In the attached diagram, the following are the reference numerals: 1. Pipe body; 2. Cover body; 3. Anti-detachment cavity; 301. First groove; 302. Second groove; 303. First water-swellable body; 304. Second water-swellable body; 305. Connecting hole; 306. Abutment pad; 40. Fixing rod; 401. Threaded blind hole; 402. Screw; 50. Water storage cavity; 51. Water outlet; 52. Installation channel; 520. Tightening section; 53. Valve ball; 521. Installation ring groove; 54. Snap ring; 55. Spring. Detailed Implementation

[0030] Reference Figures 1 to 2 The present invention provides a description of an anti-loosening, high-integrity centrifuge tube and its usage method.

[0031] For ease of explanation, spatial relative terms such as “up,” “down,” “left,” and “right” are used in the embodiments to describe the relationship of one element or feature shown in the figures relative to another element or feature. It should be understood that, in addition to the orientations shown in the figures, spatial terms are intended to include different orientations of the device in use or operation. For example, if the device in the figures is inverted, an element described as being “down” of other elements or features would be positioned “up” of those other elements or features. Therefore, the exemplary term “down” can encompass both up and down orientations. The device may be positioned in other ways (rotated 90 degrees or in other orientations), and the spatial relative descriptions used herein will be interpreted accordingly.

[0032] Moreover, relational terms such as “first” and “second” are used merely to distinguish one component from another that has the same name, without necessarily requiring or implying any such actual relationship or order between the components.

[0033] A high-integration centrifuge tube with anti-loosening features include a tube body 1 and a cover 2 detachably connected to the tube body 1. The cover 2 contains an anti-detachment cavity 3, a fixing frame axially connected to and disposed within the anti-detachment cavity 3, a first groove 301 on the fixing frame facing inwards towards the cover 2, a second groove 302 on the fixing frame facing inwards towards the tube body 1, a first water-swellable body 303 in the first groove 301, and a second water-swellable body 304 in the second groove 302. The second water-swellable body 304, after expanding upon contact with water, abuts against the end face of the tube body 1. The fixing frame has a connecting hole 305 communicating with the first groove 301. The anti-detachment cavity 3 is provided within the cover 2, and the fixing frame axially connected to and disposed within the anti-detachment cavity 3 serves as a carrier. The fixing frame facing inwards towards the cover 2... The first groove 301 and the second groove 302, which are set on the fixed frame and face the tube body 1, are connected by a first water-swellable body 303 in the first groove 301 and a second water-swellable body 304 in the second groove 302. When the centrifuge tube is centrifuged, the turbulence causes the first and second water-swellable bodies to expand upon contact with water. After the second water-swellable body 304 expands upon contact with water, it forms an expansion support between the cap 2 and the bottle body, causing the threads between the cap 2 and the bottle body to interlock, thereby improving the overall anti-detachment effect, providing strong stability and a simple structure. Furthermore, the fixed frame is provided with a connecting hole 305 that communicates with the first groove 301. The structure of the connecting hole 305 also allows the first water-swellable body 303 in the first groove 301 to expand upon contact with water, thereby forming a bidirectional expansion support effect and providing an overall interlocking effect for the threads.

[0034] The present invention is further configured such that an axial fixing structure is provided between the fixing frame and the anti-detachment cavity 3. The axial fixing structure includes a fixing rod 40 disposed in the anti-detachment cavity 3 and penetrating the fixing frame, and a limiting structure for limiting the fixing frame. The limiting structure includes a threaded blind hole 401 disposed on the fixing rod 40 and a screw 402 detachably connected to the threaded blind hole 401. In order to ensure the fixing effect of the fixing frame, an axial fixing structure is provided between the fixing frame and the anti-detachment cavity 3. The axial fixing structure includes a fixing rod 40 disposed in the anti-detachment cavity 3 and penetrating the fixing frame, and a limiting structure for limiting the fixing frame. The limiting structure includes a threaded blind hole 401 disposed on the fixing rod 40 and a screw 402 detachably connected to the threaded blind hole 401. The fixing rod 40 and the limiting structure together limit the fixing frame, while the cooperation of the screw 402 and the threaded blind hole 401 achieves the effect of easy disassembly. The structure is simple and highly practical.

[0035] The invention is further configured such that the anti-detachment cavity 3 is provided with a water storage section, which includes a water storage chamber 50, a water outlet 51 on the inner wall of the water storage chamber 50, and a one-way valve structure within the water outlet 51. The one-way valve structure is configured to be open when the centrifuge tube rotates and closed when the centrifuge tube is stationary. The cover 2 is provided with a water injection hole communicating with the water storage chamber 50. To improve the overall expansion effect, a water storage section is provided within the anti-detachment cavity 3. The part includes a water storage chamber 50, a water outlet 51 on the inner wall of the water storage chamber 50, and a one-way valve structure in the water outlet 51. When the centrifuge tube is rotating, the one-way valve is in the open state; when the centrifuge tube is stationary, the one-way valve is in the closed state. This ensures a strong expansion support effect during high-speed centrifugal motion, thereby improving the overall anti-detachment effect, strong stability, and simple structure. In addition, the cover 2 has a water injection hole that communicates with the water storage chamber 50, which facilitates the addition of water for future use.

[0036] The present invention is further configured such that the one-way valve structure includes an installation channel 52 disposed on the end face of the water outlet 51 and extending into the inner wall of the water storage chamber 50, a tightening section 520 disposed within the installation channel 52, a valve ball 53 disposed at the tightening section 520, an installation annular groove 521 disposed at the outer end of the installation channel 52, a retaining spring 54 disposed within the installation annular groove 521, and a spring 55 having one end abutting against the retaining spring 54 and the other end abutting against the valve ball 53. The one-way valve structure is further configured to include an installation channel 52 disposed on the end face of the water outlet 51 and extending into the inner wall of the water storage chamber 50, and a tightening section 520 disposed within the installation channel 52. 0. A valve ball 53 located at the tightening section 520, an installation ring groove 521 located at the outer end of the installation channel 52, a retaining ring 54 located in the installation ring groove 521, and a spring 55 with one end abutting against the retaining ring 54 and the other end abutting against the valve ball 53, through the structure of the installation channel 52 and the cooperation of the spring 55 and the valve ball 53, the spring 55 acts as a support for the valve ball 53, forming a blockage for the water outlet 51, and when the centrifuge tube is in centrifugal motion, the valve ball 53 moves outward, thereby opening the water outlet 51, increasing the expansion degree of the water-swellable body in the anti-detachment cavity 3, and improving the overall anti-detachment effect.

[0037] In this embodiment of the invention, the water storage chamber 50 has a water injection hole, and the water injection hole is provided with a cover. The cover and the water injection hole are interference fit. The above-mentioned structure is simple, practical, and easy to install and disassemble.

[0038] The invention is further configured such that the outer diameter of the tightening section 520 gradually decreases from the outside of the water storage chamber 50 to the inside of the chamber. With the above-mentioned structural configuration, the valve ball 53 is gradually tightened, resulting in good limiting effect, simple structure, and strong practicality.

[0039] The invention is further configured such that an abutment pad 306 is provided between the end face of the second water-swellable body 304 and the tube body 1, and the abutment pad 306 is made of ordinary rubber material.

[0040] The invention is further configured such that the first water-swellable body and the second water-swellable body are made of water-absorbing resin or water-swellable rubber. The water-absorbing resin and the water-swellable rubber have a significant swelling effect after contact with water. When used in centrifuge tubes, they improve the swelling support effect between the tube body 1 and the cap 2 of the centrifuge tube, realize the integrity between the tube body 1 and the cap 2 of the centrifuge tube, and ensure the anti-detachment effect. The structure is simple and highly practical.

[0041] In this embodiment of the invention, there is one water outlet 51. When in use, the water outlet 51 needs to be oriented towards the outside of the centrifuge to ensure that the water outlet 51 can discharge water normally, thus achieving full expansion of the first water-swellable body 303 and ensuring the integrity between the bottle body and the cap body 2.

[0042] A method for using the above-mentioned anti-loosening high integrity centrifuge tube includes the following steps: S1, open the water injection hole on the cover 2, add water into the water storage chamber 50, and tighten the cover 2;

[0043] S2. Place the centrifuge tubes into the centrifuge and turn on the centrifuge to perform the centrifugation operation;

[0044] S3. As the speed of the centrifuge gradually increases, the valve ball 53 of the water storage chamber 50 in the centrifuge tube pushes open the spring 55 under the centrifugal action. At this time, the water in the water storage chamber 50 is thrown out and enters the anti-detachment chamber 3.

[0045] S4. The first water-swellable body 303 in the anti-detachment cavity 3 continuously increases in volume after encountering water, and exerts pressure on the fixing frame.

[0046] S5. At the same time, when the centrifuge tube is centrifuged, the second water-swellable body 304 will also expand when it comes into contact with water and squeeze the cap 2. The threads of the cap 2 and the bottle will form an interlocking state.

[0047] S6. As the amount of water thrown out of the water storage chamber 50 gradually increases, the expansion amount of the first water-swellable body 303 is greater than that of the second water-swellable body 304. At this time, the fixing frame bends towards the inside of the bottle and seals the bottle mouth.

[0048] S7. Continue until the centrifugation operation is completed. After the centrifugation operation is completed, remove the failed first and second water-swellable bodies through the inlet and replace them for future use.

[0049] By adopting the above technical solution, beneficial effects are achieved. By using the water-swellable body as the expansion carrier, the water in the water storage chamber 50 as the expansion source, and the centrifugal motion of the centrifuge as the trigger condition, the one-way valve opens under the centrifugal motion, thereby creating the effect of water discharge. This also causes the first water-swellable body 303 to fully expand upon contact with water and compress the cap 2. The threads of the cap 2 and the bottle body will form an interlocking state. The expansion amount of the first water-swellable body 303 is greater than that of the second water-swellable body 304. At this time, the fixing frame bends towards the inside of the bottle and forms a sealing effect on the bottle mouth, greatly improving the anti-detachment effect. The structure is simple and highly practical.

[0050] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any ordinary changes and substitutions made by those skilled in the art within the scope of the technical solution of the present invention should be included within the protection scope of the present invention.

Claims

1. A centrifuge tube with high integrity and anti-loosening properties, comprising a tube body (1) and a cap (2) detachably connected to the tube body (1), characterized in that, The cover (2) contains an anti-detachment cavity (3), a fixing frame is provided in the anti-detachment cavity (3) and axially movably connected to the anti-detachment cavity (3), a first groove (301) is provided on the fixing frame and facing the inside of the cover (2), a second groove (302) is provided on the fixing frame and facing the side of the tube (1), a first water-swellable body (303) is provided in the first groove (301), and a second water-swellable body (304) is provided in the second groove (302). The fixing frame is provided with a connecting hole (305) communicating with the first groove (301). An axial fixing structure is provided between the fixing frame and the anti-detachment cavity (3). The axial fixing structure includes a fixing rod (40) disposed in the anti-detachment cavity (3) and passing through the fixing frame, and a limiting structure for limiting the fixing frame. The anti-detachment cavity (3) is provided with a water storage part, which includes a water storage cavity (50), a water outlet (51) provided on the inner wall of the water storage cavity (50), and a one-way valve structure provided in the water outlet (51). The one-way valve structure is configured to be in the open state when the centrifuge tube is rotating and in the closed state when the centrifuge tube is stationary. The cover (2) is provided with a water injection hole that communicates with the water storage cavity (50).

2. The anti-loosening, high-integrity centrifuge tube according to claim 1, characterized in that, The limiting structure includes a threaded blind hole (401) provided on the fixed rod (40) and a screw (402) detachably connected to the threaded blind hole (401).

3. The anti-loosening, high-integrity centrifuge tube according to claim 1, characterized in that, The one-way valve structure includes an installation channel (52) disposed on the end face of the outlet hole (51) and extending into the inner wall of the water storage chamber (50), a tightening section (520) disposed in the installation channel (52), a valve ball (53) disposed in the tightening section (520), an installation ring groove (521) disposed at the outer end of the installation channel (52), a retaining ring (54) disposed in the installation ring groove (521), and a spring (55) with one end abutting against the retaining ring (54) and the other end abutting against the valve ball (53).

4. A high-integrity, anti-loosening centrifuge tube according to claim 3, characterized in that, The outer diameter of the tightening section (520) gradually decreases from the outside of the water storage chamber (50) towards the inside of the chamber.

5. A high-integrity, anti-loosening centrifuge tube according to claim 1, characterized in that, A contact pad (306) is provided between the end face of the second water-swellable body (304) and the tube body (1), and the contact pad (306) is made of ordinary rubber material.

6. A high-integrity, anti-loosening centrifuge tube according to claim 1, characterized in that, The first and second water-swellable bodies are made of water-absorbing resin or water-swellable rubber.

7. A method of using the anti-loosening, high-integrity centrifuge tube according to any one of claims 1-6, characterized in that, The steps include the following: S1, open the water inlet on the cover (2), add water into the water storage chamber (50), and tighten the cover (2); S2. Place the centrifuge tubes into the centrifuge and turn on the centrifuge to perform the centrifugation operation; S3. When the speed of the centrifuge gradually increases, the valve ball (53) of the water storage chamber (50) in the centrifuge tube pushes open the spring (55) under the centrifugal action. At this time, the water in the water storage chamber (50) is thrown out and enters the anti-detachment chamber (3). S4. The first water-swellable body (303) in the anti-detachment cavity (3) increases in volume after encountering water and exerts pressure on the fixing frame. S5. At the same time, when the centrifuge tube is centrifuged, the second water-swellable body (304) will also expand when it comes into contact with water and squeeze the cap (2). The threads of the cap (2) and the bottle will form an interlocking state. S6. As the amount of water thrown out of the water storage chamber (50) gradually increases, the expansion amount of the first water-swellable body (303) is greater than that of the second water-swellable body (304). At this time, the fixing frame forms a phenomenon of bending towards the inside of the bottle and seals the bottle mouth. S7. Continue until the centrifugation operation is completed. After the centrifugation operation is completed, remove the failed first and second water-swellable bodies through the inlet and replace them for future use.

Citation Information

Patent Citations

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