A slicing device for processing pathological paraffin specimens

Abstract

The present invention relates to a slicing device for processing pathological paraffin specimens. A clamping mechanism and a slicing mechanism are provided inside the body. A spraying mechanism is provided around the slicing mechanism. The slicing mechanism includes a conical table and a slicing knife. The end face of the conical table is a right triangle. The slicing knife is arranged on the upper part of the conical table. The spraying mechanism includes a water tank, a water pump, an input pipe, a ground nozzle and a stand nozzle. The water pump is externally connected to an input pipe, and the input pipe is respectively connected to the ground nozzle and the stand nozzle. The slicing device for processing pathological paraffin specimens can accurately control the thickness of the slices, is stable and reliable during the slicing process, and is convenient for the clamping plate to clamp the paraffin block, and also avoids the paraffin block from being excessively squeezed and deformed. The present invention increases the sliding speed of the paraffin by spraying water, alcohol and surfactant to the lower part of the cutter, and also appropriately softens the paraffin to avoid serious cracking and damage of the paraffin caused by the blade, and can ensure the stability of the paraffin.

Description

Technical Field

[0001] The invention relates to the technical field of pathological paraffin wax, in particular to a slicing device for processing pathological paraffin wax specimens. Background Art

[0002] Paraffin sections are the most widely used method in conventional histological preparation techniques. Paraffin sections are not only used to observe the morphology and structure of normal cell tissues, but are also the primary method used by disciplines such as pathology and forensic medicine to study, observe, and determine morphological changes in cell tissues. They are also widely used in research in many other disciplines.

[0003] The preparation of paraffin specimens is to collect materials and fix them, and then rinse them with water, and then dehydrate, make them transparent, dip them in wax and embed them. The embedded tissue blocks can be sliced ​​as needed, which requires a slicing device. However, the existing slicing devices cannot fix the materials well during slicing, resulting in low slice quality. In addition, the knife seriously damages the paraffin slices during the slicing process. After slicing, the paraffin slices stick to the knife or the conical table and cannot fall off. Although the existing technology has used methods such as static electricity removal to solve this problem, they are all complex in structure and have unsatisfactory effects. The slicing efficiency is low and the quality is poor, which makes it difficult to meet the use requirements and the functionality is greatly limited. Therefore, a slicing device for pathological paraffin specimen processing is proposed to solve the existing problems. Summary of the Invention

[0004] In response to the shortcomings of the existing technology, the present invention provides a slicing device for processing pathological paraffin specimens, which has the advantage of being easy to slice. It solves the problems of existing slicing devices, such as the inability to fix the material well, the paraffin slices sticking to the knife or the conical table after slicing, and the knife causing serious damage to the paraffin, thereby improving the slicing quality and slicing efficiency.

[0005] To achieve the above-mentioned object, the present invention provides the following technical solution: a slicing device for processing pathological paraffin specimens, comprising a body, wherein a clamping mechanism and a slicing mechanism are provided inside the body;

[0006] The slicing mechanism is surrounded by a spray mechanism, and the slicing mechanism includes a conical platform and a slicing knife. The end surface of the conical platform is a right triangle, and the slicing knife is arranged on the upper part of the conical platform;

[0007] The spray mechanism includes a water tank, a water pump, an input pipe, a floor nozzle and a stand nozzle. The water pump is externally connected to the input pipe, and the input pipe is respectively connected to the floor nozzle and the stand nozzle.

[0008] Furthermore, the clamping mechanism described in the present invention includes a longitudinal moving structure, a vertical moving structure and a clamping plate; the longitudinal moving structure includes a longitudinal skeleton, a first slide rail, a second slide rail and a spiral micrometer mechanism, and the longitudinal skeleton is connected to the body through the first slide rail and the spiral micrometer mechanism; the vertical moving structure includes a pneumatic telescopic rod, a stabilizing mechanism and a fixing mechanism, the pneumatic telescopic rod is fixed on the longitudinal moving structure, and a clamping plate is connected to the front of the pneumatic telescopic rod, and a stabilizing mechanism and a fixing mechanism are provided on both sides of the clamping plate.

[0009] Furthermore, the stabilizing mechanism of the present invention includes a telescopic rod, a return spring assembly, a vertical plate and a horizontal plate; the horizontal plate is connected to the longitudinal frame through a second slide rail, a vertical plate is provided under the horizontal plate, a return spring assembly is provided in the middle of the vertical plate, a telescopic rod is provided at the bottom of the vertical plate, and a fixing mechanism is provided at the upper part of the vertical plate.

[0010] Furthermore, the reset spring assembly of the present invention includes a pull rod and a spring. The pull rod passes through and extends to the outside of the vertical plate. One end of the pull rod close to the clamping plate is fixedly connected to the clamping plate.

[0011] Furthermore, the fixing mechanism described in the present invention includes a connecting plate, a plug-in block, a third slide rail, an electric push rod and a connecting block. The electric push rod and the third slide rail are provided on the vertical plate. A connecting plate is provided on the upper part of the electric push rod. The connecting plate and the vertical plate are connected through the third slide rail. A connecting block is provided at the end of the connecting plate. A plug-in block is provided on the clamping plate. The plug-in block and the connecting block are magnetically connected.

[0012] Furthermore, the clamping plate of the present invention includes a clamping side wall and a clamping bottom plate. The clamping bottom plate is provided with guide bars on the upper and lower sides respectively. The clamping side wall is arranged between the guide bars and is movably connected to the guide bars.

[0013] Furthermore, the conical platform and the slicing knife of the present invention are connected in an arc shape.

[0014] Furthermore, the stand nozzle of the present invention is directly facing the upper part of the arc connecting the conical table and the slicing knife.

[0015] Furthermore, the water pump of the present invention is provided with a liquid supply mechanism outside, and a spraying liquid is provided inside the liquid supply mechanism. The spraying liquid is water, alcohol and surfactant, and the mass ratio of water: alcohol: surfactant is 95:4:1.

[0016] Furthermore, the floor sprinklers of the present invention are provided in a plurality of groups, and the floor sprinklers are evenly arranged on the bottom of the water tank and on the side opposite to the conical platform.

[0017] Compared with the existing technology, the technical solution of this application has the following beneficial effects:

[0018] The slicing device for processing pathological paraffin specimens can accurately advance the paraffin block through structures such as a spiral micrometer mechanism and a first slide rail, thereby accurately controlling the thickness of the slice. At the same time, a reset spring assembly, a vertical plate, and a horizontal plate are used for positioning and clamping, and a fixing mechanism is used to ensure stability and reliability during the slicing process, making it easier for the clamping plate to clamp the paraffin block and preventing the paraffin block from being excessively squeezed and deformed.

[0019] The present invention increases the sliding speed of the paraffin wax by spraying water, alcohol and surfactant on the lower part of the cutter, appropriately softens the paraffin wax, avoids severe cracking and damage of the paraffin wax caused by the cutting edge, and ensures the stability of the paraffin wax.

[0020] Use the ground nozzle to slowly let water in upwards, forming an upward diffusion force underwater, which is conducive to the rapid expansion of the paraffin block. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a cross-sectional view of the structure of the present invention;

[0022] Figure 2 This is a schematic structural diagram of the wax block clamping mechanism of the present invention;

[0023] Figure 3 This is a schematic diagram of the wax block slicing mechanism structure of the present invention;

[0024] Figure 4 For the present invention Figure 1 Schematic diagram of the enlarged structure of A shown.

[0025] In the figure: 1 base, 2 support column, 3 body, 4 slicer, 5 longitudinal moving structure, 501 first slide rail, 502 screw micrometer mechanism, 503 second slide rail, 504 longitudinal skeleton, 6 pneumatic telescopic rod, 7 clamping plate, 701 clamping side wall, 702 clamping bottom plate, 8 stabilizing mechanism, 801 telescopic rod, 802 return spring assembly, 803 vertical plate, 804 horizontal plate, 9 fixing mechanism, 901 connecting plate, 902 plug-in block, 903 third slide rail, 904 electric push rod, 905 connecting block, 10 water pump, 101 input pipe, 102 floor nozzle, 103 stand nozzle, 104 water tank, 11 conical table. DETAILED DESCRIPTION

[0026] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0027] See also Figure 1-4In this embodiment, a pathological paraffin specimen processing and slicing device includes a base 1, a support column 2, and a body 3. The support column 2 is fixedly mounted on the upper surface of the base 1, and the body 3 is fixedly mounted on the upper surface of the support column 2. A clamping mechanism and a slicing mechanism are provided inside the body 3.

[0028] The slicing mechanism is surrounded by a spray mechanism, and the slicing mechanism includes a conical platform 11 and a slicing knife 4. The end surface of the conical platform 11 is a right triangle, and the slicing knife 4 is arranged on the upper part of the conical platform 11;

[0029] The spray mechanism includes a water tank 104, a water pump 10, an input pipe 101, a floor sprinkler 102, and a stand sprinkler 103. The water pump 10 is externally connected to the input pipe 101, which is respectively connected to the floor sprinkler 102 and the stand sprinkler 103. The floor sprinkler 102 and the stand sprinkler 103 are respectively equipped with a waterproof solenoid valve.

[0030] In this embodiment, the clamping mechanism includes a longitudinal moving structure 5, a vertical moving structure and a clamping plate 7; the longitudinal moving structure 5 includes a longitudinal skeleton 504, a first slide rail 501, a second slide rail 503 and a screw micrometer mechanism 502, and the longitudinal skeleton 504 is connected to the body 3 through the first slide rail 501 and the screw micrometer mechanism 502; the vertical moving structure includes a pneumatic telescopic rod 6, a stabilizing mechanism 8 and a fixing mechanism 9, the pneumatic telescopic rod 6 is fixed on the longitudinal moving structure 5, and the front of the pneumatic telescopic rod 6 is connected to the clamping plate 7, and the stabilizing mechanism 8 and the fixing mechanism 9 are provided on both sides of the clamping plate 7.

[0031] It should be noted that the micrometer screw mechanism 502 of the present invention is the same as the rotary propulsion structure on a common precision moving platform or micrometer screw, and is a common micron-level moving control structure.

[0032] In this embodiment, the stabilizing mechanism 8 comprises a telescopic rod 801, a return spring assembly 802, a vertical plate 803, and a horizontal plate 804. The horizontal plate 804 is connected to the longitudinal frame 504 via a second slide rail 503. The vertical plate 803 is located below the horizontal plate 804, and the return spring assembly 802 is located in the middle of the vertical plate 803. The telescopic rod 801 is located at the bottom of the vertical plate 803, and the fixing mechanism 9 is located above the vertical plate 803. The second slide rail 503 is made of rubber, which creates a strong friction between it and the longitudinal frame 504. This resistance prevents the vibration caused by unstable airflow when the pneumatic telescopic rod 6 is advanced, ensuring slow and stable advancement of the paraffin block.

[0033] It should be noted that the reset spring assembly 802 of the present invention includes a pull rod and a spring. The pull rod passes through and extends to the outside of the vertical plate. One end of the pull rod close to the clamping plate 7 is fixedly connected to the clamping plate 7.

[0034] In this embodiment, the fixing mechanism 9 includes a connecting plate 901, a plug-in block 902, a third slide rail 903, an electric push rod 904 and a connecting block 905. The vertical plate 803 is provided with an electric push rod 904 and a third slide rail 903. The upper part of the electric push rod 904 is provided with a connecting plate 901. The connecting plate 901 and the vertical plate 803 are connected through the third slide rail 903. The end of the connecting plate 901 is provided with a connecting block 905. The clamping plate 7 is provided with a plug-in block 902. The plug-in block 902 and the connecting block 905 are magnetically connected.

[0035] It should be noted that the magnetic connection between the plug-in block 902 and the connecting block 905 of the present invention can not only ensure that the connection will not slide and is stable and reliable, but also cooperate with the pneumatic telescopic rod 6 and the electric push rod 904 to facilitate their separation. The reset spring assembly 802 pulls open the clamping side walls 701 on both sides of the clamping plate 7 to clamp the paraffin block.

[0036] It should be noted that the electric push rod 901 is a micro electric push rod.

[0037] In this embodiment, the clamping plate 7 includes a clamping side wall 701 and a clamping bottom plate 702 . The clamping bottom plate 702 is provided with guide bars on the upper and lower sides respectively. The clamping side wall 701 is arranged between the guide bars and is movably connected to the guide bars.

[0038] In this embodiment, the conical platform 11 and the slicing knife 4 are connected in an arc shape to prevent the paraffin cut by the slicing knife from breaking due to a large turning angle at the blade edge.

[0039] In this embodiment, the stage nozzle 103 of the present invention is directly facing the upper part of the arc connecting the conical stage 11 and the slicing knife 4.

[0040] In this embodiment, the water pump 10 of the present invention is externally provided with a liquid supply mechanism, which is internally provided with a spray liquid. The spray liquid comprises water, alcohol, and a surfactant, with the mass ratio of water:alcohol:surfactant being 95:4:1. After numerous tests, the present invention determined that the surfactant used in the present invention was disodium lauryl sulfosuccinate, which is required to ensure the stability of paraffin wax while also preventing it from being too slippery to remain stable on a glass slide.

[0041] In this embodiment, the floor nozzles 102 are provided in several groups and are evenly distributed on the bottom of the water tank 104 and on the side opposite the conical platform 11. These form upward water waves, which provide a weak expansion force and increase the water tension. Combined with the tension provided by the surfactant, this makes it easier for the paraffin sheet to unfold.

[0042] The working principle of the above embodiment is:

[0043] After the pneumatic telescopic rod 6 is stable, the electric push rod 904 is turned on and pushed open, the plug block 902 and the connecting block 905 are disconnected, the pull rod of the stabilizing mechanism 8 is pulled open to put the paraffin block in, the pull rod is released and reset by the spring, the electric push rod 904 is retracted to make the plug block 902 and the connecting block 905 combined, the water pump 10 is turned on to spray liquid through the ground nozzle 102 and the stage nozzle 103 to lubricate the conical table 11, the pneumatic telescopic rod 6 is turned on to push the paraffin block down, the spiral micrometer mechanism 502 is adjusted so that the paraffin is just lifted up when it is close to the slicer 4, and then the spiral micrometer mechanism 502 is adjusted to obtain the slice thickness of the appropriate size, and the pneumatic telescopic rod 6 is started again, and the slice is pressed down. At this time, there is already a suitable height of spray liquid in the water tank 104, which can provide tension for the cut paraffin slice to unfold. When the paraffin falls in, it is quickly flattened, and the slide is placed from the lower side of the water tank 104 to the bottom of the paraffin slice, and it is gently lifted up so that the paraffin slice is flat on the slide.

[0044] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply the existence of any such actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article, or device comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or elements inherent to such process, method, article, or device. In the absence of further limitations, an element defined by the phrase "comprising a ..." does not exclude the presence of other identical elements in the process, method, article, or device comprising the element.

[0045] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A device for slicing pathological paraffin specimens, comprising a body, characterized in that: The interior of the machine body is provided with a clamping mechanism and a slicing mechanism; The slicing mechanism is surrounded by a spray mechanism, and the slicing mechanism includes a conical platform and a slicing knife. The end surface of the conical platform is a right triangle, and the slicing knife is arranged on the upper part of the conical platform; The spray mechanism includes a water tank, a water pump, an input pipe, a floor nozzle and a stand nozzle. The water pump is externally connected to an input pipe, and the input pipe is respectively connected to the floor nozzle and the stand nozzle; The clamping mechanism includes a longitudinal moving structure, a vertical moving structure and a clamping plate; the longitudinal moving structure includes a longitudinal frame, a first slide rail, a second slide rail and a screw micrometer mechanism, and the longitudinal frame is connected to the body through the first slide rail and the screw micrometer mechanism; the vertical moving structure includes a pneumatic telescopic rod, a stabilizing mechanism and a fixing mechanism, the pneumatic telescopic rod is fixed to the longitudinal moving structure, the front of the pneumatic telescopic rod is connected to the clamping plate, and the stabilizing mechanism and the fixing mechanism are provided on both sides of the clamping plate; The stabilizing mechanism includes a telescopic rod, a return spring assembly, a vertical plate and a horizontal plate; the horizontal plate is connected to the longitudinal frame through a second slide rail, a vertical plate is provided under the horizontal plate, a return spring assembly is provided in the middle of the vertical plate, a telescopic rod is provided at the bottom of the vertical plate, and a fixing mechanism is provided at the upper part of the vertical plate; The return spring assembly includes a pull rod and a spring. The pull rod passes through and extends to the outside of the vertical plate. One end of the pull rod close to the clamping plate is fixedly connected to the clamping plate. The fixing mechanism includes a connecting plate, a plug-in block, a third slide rail, an electric push rod and a connecting block. The electric push rod and the third slide rail are provided on the vertical plate. A connecting plate is provided on the upper part of the electric push rod. The connecting plate and the vertical plate are connected through the third slide rail. A connecting block is provided at the end of the connecting plate. The plug-in block is provided on the clamping plate. The plug-in block and the connecting block are magnetically connected. The conical platform and the slicing knife are connected in an arc.

2. The device for processing pathological paraffin specimens according to claim 1, characterized in that: The clamping plate includes a clamping side wall and a clamping bottom plate. The clamping bottom plate is provided with guide bars on the upper and lower sides respectively. The clamping side wall is arranged between the guide bars and is movably connected to the guide bars.

3. The device for processing pathological paraffin specimens according to claim 1, characterized in that: The stand nozzle is directly opposite to the upper portion of the arc connecting the conical stand and the slicing knife.

4. The device for processing pathological paraffin specimens according to claim 1, characterized in that: A liquid supply mechanism is provided outside the water pump, and a spraying liquid is provided inside the liquid supply mechanism. The spraying liquid is water, alcohol and surfactant, and the mass ratio of water: alcohol: surfactant is 95:4:

1.

5. The pathological paraffin specimen processing device according to claim 1, characterized in that: The floor sprinklers are provided in a plurality of groups and are evenly arranged on the bottom of the water tank and on a side opposite to the conical platform.

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