An apparatus and method for extracting plants for use in anaesthesia

By designing a three-stage grinding structure and ultrasonic extraction technology for anesthetic plant extraction equipment, the problem of insufficient grinding in existing equipment has been solved, and efficient extraction of effective components from anesthetic plants has been achieved.

CN116212443BActive Publication Date: 2026-04-21WEST CHINA HOSPITAL SICHUAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
WEST CHINA HOSPITAL SICHUAN UNIV
Filing Date
2023-02-23
Publication Date
2026-04-21

AI Technical Summary

Technical Problem

Existing equipment does not grind plants sufficiently, resulting in a low extraction rate of active ingredients from anesthetic plants.

Method used

Design a plant extraction device for anesthesia, which adopts a three-stage grinding structure. By changing the distance between the grinding plate and the inner wall of the grinding cylinder through grinding components and connecting components, and combining ultrasonic extraction technology, the device can achieve thorough grinding of plants and extraction of effective components.

Benefits of technology

It improved the extraction rate of active ingredients from anesthetic plants, shortened the grinding time, and increased the extraction efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application discloses anesthetic plant extraction equipment and method, the anesthetic plant extraction equipment in the application includes support, grinding unit and extraction unit, grinding unit and extraction unit are located on the support, wherein, the grinding unit includes grinding piece and connecting piece, in the application, the distance between the grinding plate and the inner side wall of the grinding cylinder in the grinding structure is changed through the interaction of the grinding piece and the connecting piece, that is, in the application, the distance between the grinding plate and the inner side wall of the grinding cylinder is changed, so that the anesthetic plant successively experiences primary grinding, secondary grinding and tertiary grinding, so that the grinding time can be shortened to a certain extent, and meanwhile, the anesthetic plant can be fully ground, and the extraction of effective components in the anesthetic plant is facilitated.
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Description

Technical Field

[0001] This invention relates to the field of pharmaceutical technology, specifically to a plant extraction device and method for anesthetic purposes. Background Technology

[0002] Anesthetics are drugs or non-drug methods that reversibly block nerve conduction at the site of action, causing temporary loss of sensation in the local area. Nerve impulse conduction is weakened due to reduced permeability of the nerve cell membrane to sodium ions. This change in membrane permeability lowers the membrane depolarization level and raises the excitability threshold, ultimately blocking the formation of nerve cell action potentials to achieve painless surgical treatment.

[0003] Currently, commonly used narcotic drugs on the market include etorphine, acetylalfamethylfentanyl, and methadone, all of which are prone to physical and psychological dependence and can lead to addiction if used continuously, abused, or used inappropriately.

[0004] Based on this, those skilled in the art have selected some plant extracts to prepare anesthetics. For example, in the technology with patent number 201810362997.3 and patent name: "An Easily Metabolizable Plant Extract for Anesthetics and Its Manufacturing Method", extracts of Rhododendron molle and Aconitum carmichaelii are used to replace existing acetoprene, acetylalfamethylfentanyl, methadone, etc.; in the technology with patent number 201810362979.5 and patent name: "A Plant Extract for Anesthetics with Low Aftereffects and Its Manufacturing Method", extracts of Datura stramonium and Scopolamine scabra are used to replace existing acetoprene, acetylalfamethylfentanyl, methadone, etc.

[0005] Currently, the main method for extracting active ingredients from plants involves first extracting the active ingredients with a solvent, then filtering the solution through heat and condensing it to crystallize, thus achieving the goal of extracting the active ingredients. However, the cell walls of plants are difficult to break down, resulting in a low extraction rate of active ingredients.

[0006] Therefore, grinding plants has become one of the key research directions for improving the extraction rate of effective components from plants. The patent with patent number 201910605541.X and patent name "A Plant Extraction Cell Wall Breaker" provides a device that combines pulverization and grinding. This device first pulverizes the plant, and then only performs one stage of grinding on the pulverized plant. Therefore, this device suffers from insufficient grinding, which is not conducive to the subsequent extraction of effective components from the plant and achieving the goal of increasing the extraction rate of effective components.

[0007] Therefore, there is an urgent need to study a device and method that can improve the extraction rate of effective components from anesthetic plants. Summary of the Invention

[0008] To address the problem of insufficient plant grinding in existing equipment, one objective of this invention is to provide a plant extraction device for anesthesia.

[0009] The technical solution of the present invention to solve the above-mentioned technical problems is as follows:

[0010] An anesthetic plant extraction device, the extraction device comprising:

[0011] support;

[0012] The grinding unit includes a grinding cylinder with an inlet and an outlet located on a support, a rotating shaft arranged along the axis of the grinding cylinder and connected to the support, and a motor located at one end of the rotating shaft; grinding parts distributed around the rotating shaft, the grinding parts being movably connected to the rotating shaft via connecting parts, and locking parts located at both ends of the grinding parts and connected to the rotating shaft;

[0013] The grinding component includes a first plate, a second plate, and a third plate arranged radially along the rotation axis, with the first plate close to the rotation axis and a grinding structure located on the third plate;

[0014] The connecting component includes a first connecting block, a second connecting block, and a third connecting block located on the first plate, the second plate, and the third plate respectively, with their lengths increasing sequentially, and a support disposed on the rotating shaft. The first connecting block, the second connecting block, and the third connecting block all extend toward the rotating shaft and are matched with the support. The extended end of the third connecting block passes through the second plate and the first plate in sequence, and the extended end of the second connecting block passes through the first plate. When the grinding workpiece moves along the axis of the rotating shaft, the first connecting block, the second connecting block, and the third connecting block are connected to the support in sequence.

[0015] The extraction unit, located on the support, is used to extract the active ingredients from ground anesthetic plants.

[0016] Based on the above technical solution, the present invention can be further improved as follows:

[0017] Furthermore, the locking component includes a connecting disc sleeved on the rotating shaft, a locking block located on the rotating shaft, the locking block located outside the grinding cylinder, a connecting plate disposed at the ends of the first plate, the second plate, and the third plate, and a through hole located on the connecting disc and matching the locking block; wherein, the connecting disc and the locking block are connected by bolts, and the connecting plate and the connecting disc are connected by bolts; the locking blocks are in 3 groups and are equally spaced along the axis of the rotating shaft, and the distance between each group of locking blocks is equal to the distance between the first connecting block, the second connecting block, and the third connecting block.

[0018] Furthermore, a groove is provided on the side of the connecting plate near the grinding cylinder, and a slider matching the groove is provided on the connecting plate.

[0019] Furthermore, the grinding structure includes connecting posts distributed on the third plate, one end of which extends toward the inner wall of the grinding cylinder, and a grinding plate located at the extended end of the connecting post.

[0020] Furthermore, the third plate is provided with a baffle extending toward the inner wall of the grinding cylinder, the baffle being close to the end of the grinding cylinder; there are two sets of baffles and the two sets of baffles are symmetrically positioned.

[0021] Furthermore, the first, second, and third plates are all arc-shaped and coaxially arranged; the grinding plate is arc-shaped.

[0022] Furthermore, the extraction unit includes an extraction cylinder located on the support and below the grinding cylinder, an inlet and an outlet located on the extraction cylinder, an ultrasonic vibration source located on the extraction cylinder, a vibrating head located in the extraction cylinder and connected to the ultrasonic vibration source, and a condenser tube located at the bottom of the extraction cylinder.

[0023] Furthermore, the support includes a first pillar, a second pillar, and a first support plate and a second support plate connected sequentially from top to bottom between the first pillar and the second pillar; the grinding cylinder is located on the first support plate, the extraction cylinder is located on the second support plate, and the two ends of the rotating shaft are connected to the first pillar and the second pillar respectively through bearings.

[0024] The second objective of this invention is to provide a method for extracting the active ingredients from anesthetic plants, comprising the following steps:

[0025] Step 1: Add the powdered anesthetic plant into the grinding cylinder and perform three-stage grinding of the anesthetic plant, including first-stage grinding of the anesthetic plant by connecting the first connecting block and the support, second-stage grinding of the anesthetic plant by connecting the second connecting block and the support, and third-stage grinding of the anesthetic plant by connecting the third connecting block and the support.

[0026] Step 2: Input the anesthetic plant that has undergone three-stage grinding into an extraction tube containing solvent, start the ultrasonic vibration source to extract the effective components from the anesthetic plant in the extraction tube, and obtain the extract after filtration;

[0027] Step 3: The extract is subjected to macroporous adsorption resin for adsorption and decolorization, elution, and concentration to obtain the active ingredient.

[0028] Furthermore, the particle size of the anesthetic plant in step 1 is 0.5–1.0 mm; the solvent in step 2 is ethanol; and elution is performed using ethanol in step 3.

[0029] The present invention has the following beneficial effects:

[0030] 1. In this invention, the distance between the grinding plate and the inner wall of the grinding cylinder in the grinding structure is changed by the interaction between the grinding component and the connecting component; that is, by changing the distance between the grinding plate and the inner wall of the grinding cylinder, the anesthetic plants undergo primary grinding, secondary grinding and tertiary grinding in sequence. This not only shortens the grinding time to a certain extent, but also achieves sufficient grinding of the anesthetic plants, which is conducive to the extraction of effective components from the anesthetic plants.

[0031] 2. In this invention, based on the thorough grinding of anesthetic plants, ultrasonic extraction is used to extract the effective components of anesthetic plants, which can further improve the yield of effective components extracted from anesthetic plants. Attached Figure Description

[0032] Figure 1 This is a schematic diagram of the structure of the plant extraction device for anesthesia in this invention;

[0033] Figure 2 This is a schematic diagram of the left-side structure of the grinding unit in this invention;

[0034] Figure 3 This is an enlarged left-side view of the grinding component in this invention;

[0035] Figure 4 This is a magnified structural diagram of region A;

[0036] Figure 5 This is an enlarged cross-sectional view of the connector in this invention.

[0037] Figure 6 This is a magnified structural diagram of region B;

[0038] Explanation of reference numerals in the attached figures:

[0039] 100 - Support frame, 110 - First support column, 120 - Second support column, 130 - First support plate, 140 - Second support plate;

[0040] 200-Grinding unit, 210-Grinding cylinder, 220-Feed inlet, 230-Discharge outlet, 240-Rotating shaft, 250-Motor, 260-Grinding component, 261-First plate, 262-Second plate, 263-Third plate, 264-Grinding structure, 1-Connecting column, 2-Grinding plate, 270-Connecting component, 271-First connecting block, 272-Second connecting block, 273-Third connecting block, 274-Support, 275-Card block, 276-Card groove, 277-Slope, 280-Locking component, 281-Connecting disc, 282-Locking block, 283-Connecting plate, 284-Perforation, 285-Slide groove, 286-Slider, 290-Baffle;

[0041] 300 - Extraction unit, 310 - Extraction cylinder, 320 - Liquid inlet, 330 - Liquid outlet, 340 - Ultrasonic vibration source, 350 - Vibration head, 360 - Condenser tube. Detailed Implementation

[0042] Example embodiments will now be described more fully with reference to the accompanying drawings. However, it should not be construed that the embodiments of this disclosure are limited to those described herein. The same reference numerals in the drawings denote the same or similar structures, and therefore their detailed descriptions will be omitted.

[0043] In the description of this disclosure, it should be understood that the terms “center,” “upper,” “lower,” “front,” “rear,” “left,” “right,” “vertical,” “horizontal,” “top,” “bottom,” “inner,” and “outer,” etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this disclosure and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this disclosure.

[0044] The terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this disclosure, unless otherwise stated, "a plurality of" means two or more.

[0045] In the description of this disclosure, it should be noted that, unless otherwise expressly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection between two components. Those skilled in the art can understand the specific meaning of the above terms in this disclosure according to the specific circumstances.

[0046] The present invention will now describe a plant extraction device and method for anesthetic purposes.

[0047] However, the invention may be exemplified in many different forms and should not be construed as limited to the specific inventions set forth herein. Rather, these inventions are provided so that the invention will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art.

[0048] The anesthetic plant extraction device of this invention is mainly used to extract the effective components from anesthetic plants. It changes the distance between the grinding plate and the inner wall of the grinding cylinder by the interaction of the grinding components and the connecting components. That is, by changing the distance between the grinding plate and the inner wall of the grinding cylinder, the anesthetic plants undergo primary grinding, secondary grinding and tertiary grinding in sequence. This not only shortens the grinding time to a certain extent, but also achieves sufficient grinding of the anesthetic plants, which is conducive to the extraction of the effective components from the anesthetic plants.

[0049] In addition, in practice, this plant extraction equipment for anesthesia can also be used to extract active ingredients from other plants, such as polypeptides.

[0050] The following is a detailed description of the plant extraction equipment and method for anesthesia in this invention.

[0051] The first aspect of this invention provides a plant extraction device for anesthetic purposes; such as... Figures 1-6 The anesthetic plant extraction device of this invention includes a support 100, a grinding unit 200, and an extraction unit 300, wherein both the grinding unit 200 and the extraction unit 300 are located on the support 100. In this invention, the anesthetic plant is ground by the grinding unit and then enters the extraction unit for the extraction of its active ingredients.

[0052] Specifically, the support 100 includes a first pillar 110, a second pillar 120, and a first support plate 130 and a second support plate 140 connected from top to bottom between the first pillar 110 and the second pillar 120; the grinding unit 200 in this invention is located on the first support plate 130, and the extraction unit 300 is located on the second support plate 140.

[0053] according to Figures 1-6 The grinding unit 200 of this invention includes a grinding cylinder 210, a feed inlet 220, a discharge outlet 230, a rotating shaft 240, a motor 250, a grinding component 260, a connecting component 270, and a locking component 280. Specifically, the grinding cylinder 210 is located on the first support plate 130, and both the feed inlet 220 and the discharge outlet 230 are located on the side wall of the grinding cylinder 210, with the feed inlet 220 located above the discharge outlet 230. In this invention, the discharge outlet 230 is provided with a baffle (not shown in the figures) that is connected to the side wall of the grinding cylinder 210 by a hinge and matches the discharge outlet 230. One end of the baffle is connected to the side wall of the grinding cylinder 210 by a hinge, and the other end is connected to the side wall of the grinding cylinder 210 by a snap-fit. In addition, to prevent the material in the grinding cylinder 210 from leaking out from the gap between the baffle and the discharge outlet 230, a sealing ring (not shown in the figures) is provided at the discharge outlet 230.

[0054] A rotating shaft 240 is arranged along the axis of the grinding cylinder 210 and passes through the grinding cylinder 210. In this embodiment, one end of the rotating shaft 240 is connected to the second support column 120 via a bearing, and the other end is connected to the first support column 110 via a bearing. A motor 250 is located on one end of the rotating shaft 240. In this invention, the motor 250 is located on the end of the rotating shaft 240 closer to the second support column 120. Grinding parts 260 are distributed around the rotating shaft 240. The grinding parts 260 and the rotating shaft 240 are movably connected via connecting parts 270. Locking parts 280 are located at both ends of the grinding parts 260, and the grinding parts 260 and the rotating shaft 240 are further connected via locking parts 280.

[0055] In this embodiment, the number of grinding parts is four, and they are evenly distributed around the rotating shaft. According to... Figures 1-6 The grinding element 260 of this invention includes a first plate 261, a second plate 262, a third plate 263, and a grinding structure 264. Specifically, the first plate 261, the second plate 262, and the third plate 263 are arranged radially 240 along the rotation axis, wherein the first plate 261 is close to the rotation axis 240, the third plate 263 rotates along the rotation axis 240, and the second plate 262 is located between the first plate 261 and the third plate 263; the grinding structure 264 is located on the third plate 263. Furthermore, the grinding structure 264 of this invention includes connecting posts 1 and grinding plates 2. In this invention, multiple connecting posts 1 are provided and evenly distributed on the third plate 263, extending towards the inner wall of the grinding cylinder 210, and the grinding plates 2 are located on the extended ends of the connecting posts 1.

[0056] In this invention, to further improve the fineness of grinding the anesthetic plants, the grinding plate 2 is arc-shaped. The arc shape facilitates contact between the grinding plate and the inner wall of the grinding cylinder 210, thereby improving the fineness of grinding the anesthetic plants. Furthermore, the inner wall of the grinding cylinder 210 and the side of the grinding plate 2 closest to the grinding cylinder 210 are both provided with a frosted layer (not shown in the drawings), further enhancing the fineness of grinding the anesthetic plants.

[0057] In addition, in order to reduce the resistance generated by the first plate 261, the second plate 262 and the third plate 263 when the rotating shaft 240 drives the grinding workpiece 260 to rotate, preferably, the first plate, the second plate and the third plate in the present invention are all arc-shaped, and the first plate, the second plate and the third plate are coaxially arranged and the distance from the rotating shaft 240 increases sequentially.

[0058] To enable the rotating shaft 240 to drive the grinding element 260, the connecting element 270 includes a first connecting block 271, a second connecting block 272, a third connecting block 273, and a support 274. The support 274 is located on the rotating shaft 240. The first connecting block 271, the second connecting block 272, and the third connecting block 273 are located on the first plate 261, the second plate 262, and the third plate 263, respectively, with their lengths increasing sequentially, and all extending towards the rotating shaft. Furthermore, in this embodiment, the extension end of the third connecting block 273 passes through the second plate 262 and the first plate 261 sequentially, and the extension end of the second connecting block 272 passes through the first plate 261. When the grinding element 260 moves along the axis of the rotating shaft 240, the first connecting block 271, the second connecting block 272, and the third connecting block 273 are sequentially connected to the support 274, thereby changing the distance between the grinding plate and the inner wall of the grinding cylinder, enabling fine grinding of anesthesia plants to varying degrees.

[0059] Furthermore, the third connecting block 273 in this invention can move radially relative to the first plate 261 and the second plate 262 along the rotation axis 240, and the second connecting block 272 can move radially relative to the first plate 261 along the rotation axis 240. According to... Figures 1-6 As shown, the height of the third connecting block 273 in this application is slightly less than the sum of the heights of the first connecting block 271 and the support 274.

[0060] To improve the stability of the first connecting block 271, the second connecting block 272, and the third connecting block 273 when connected to the support 274, and to prevent displacement of the first connecting block 271, the second connecting block 272, or the third connecting block 273 on the support 274 during the rotation of the grinding workpiece 260 driven by the rotating shaft 240; according to Figures 1-6 The support 274 has a locking block 275 protruding towards the side wall of the grinding cylinder 210 at its top. The extension ends of the first connecting block 271, the second connecting block 272, and the third connecting block 273 are all provided with a locking groove 276 that is recessed towards the side wall of the grinding cylinder 210 and matches the locking block 275. In this invention, when the locking block 275 and the locking groove 276 are used together, the stability between the first connecting block 271, the second connecting block 272, or the third connecting block 273 and the support 274 can be improved.

[0061] In addition, in order to facilitate the replacement of the first connecting block 271 on the support 274 with the second connecting block 272, or the second connecting block 272 with the third connecting block 273, the support 274 in this application is provided with slopes 277 on both sides.

[0062] In addition, in order to improve the stability of the drive shaft 240 driving the grinding workpiece 260 to rotate, according to Figure 1 As shown, the connectors 270 in this invention are in three groups and are distributed along the rotation axis 240.

[0063] Taking the initial state of the first connecting block 271 connected to the support 274 as an example, the change in the distance between the grinding plate and the inner wall of the grinding cylinder in this invention will be explained. Specifically, when the first plate 261, the second plate 262, and the third plate 263 move away from the motor 250, the first connecting block 271 moves away from the support along the slope on one side of the support 274. As it continues to move, the second connecting block climbs onto the support from the slope on the other side of the support and is fixed by a locking block and a locking groove. Continuing to move, the second connecting block moves away from the support along the slope on one side of the support. Further moving, the third connecting block 273 climbs onto the support from the slope on the other side and is fixed by a locking block and a locking groove. Since the lengths of the first, second, and third connecting blocks increase sequentially in this invention, while the height of the support remains constant and the height of the third connecting block is less than the sum of the heights of the first connecting block and the support, the distance from the third plate to the rotating shaft differs when connecting blocks of different heights are connected to the support, thereby changing the distance between the grinding plate and the inner wall of the grinding cylinder. In this invention, when the first connecting block is connected to the support, the anesthetic plant extraction device can be used to perform primary grinding on the material entering the device. After primary grinding for a period of time, the first, second, and third plates can be pulled away from the motor, allowing the second connecting block to connect to the support. At this time, the device can perform secondary grinding on the material after primary grinding. After secondary grinding for a period of time, the first, second, and third plates can be pulled away from the motor, allowing the third connecting block to connect to the support. At this time, the device can perform a more refined tertiary grinding on the material after secondary grinding. Through three different stages of grinding, not only can the grinding speed be increased, but the degree of fine grinding can also be improved.

[0064] To improve the stability of the rotation process of the rotating shaft 240 driving the grinding part 260 to rotate, locking parts 280 are provided at both ends of the grinding part 260. Furthermore, the grinding part in this invention is further connected to the rotating shaft through the locking parts, thereby enhancing the stability of the rotating shaft 240 driving the grinding part 260 to rotate.

[0065] like Figures 1-6 The locking element 280 in this invention includes a connecting disc 281, a locking block 282, a connecting plate 283, and a through hole 284. Specifically, the connecting disc 281 is sleeved on the rotating shaft and connected to the rotating shaft 240 via a bearing. The locking block 282 is located on the rotating shaft 240 and outside the grinding cylinder 210. The connecting plate 283 is located at the ends of the first plate 261, the second plate 262, and the third plate 263. The through hole 284 is located on the connecting disc 281 and matches the locking block 282. The connecting disc 281 and the locking block 282 are connected by bolts, and the connecting plate 283 and the connecting disc 281 are connected by bolts. Furthermore, according to... Figures 1-6As shown, the locking blocks 282 in this invention are in three groups and are distributed at equal intervals along the axis of the rotation axis 240. The distance between each group of locking blocks 282 is equal to the distance between the first connecting block, the second connecting block and the third connecting block. In addition, each group of locking blocks 282 consists of two blocks and their positions are symmetrical about the axis of the rotation axis.

[0066] In this invention, when the first plate 261, the second plate 262, and the third plate 263 are moved along the axis of the rotation shaft 240 by the connecting plate 281, the connecting plate 281 is rotated and passes through the locking block 282 through the through hole 284, thereby enabling the connecting plate to connect with the locking blocks at different positions. In addition, since the distance between each group of locking blocks 282 is equal to the distance between the first connecting block 271, the second connecting block 272, and the third connecting block 273, the first connecting block 271, the second connecting block 272, and the third connecting block 273 on the support 274 can be replaced more accurately by connecting the connecting plate 281 with the locking blocks 282 at different positions.

[0067] To prevent the first plate 261, the second plate 262, and the third plate 263 from shaking when adjusting the distance between the grinding plate 2 and the inner wall of the grinding cylinder 210; Figure 1 As shown, the connecting plate 281 has a groove 285 on the side near the grinding cylinder 210, and the connecting plate 283 has a slider 286 that matches the groove 285.

[0068] In order to reduce the escape of material from the gap between the third plate 263 and the end of the grinding cylinder 210 during the grinding process, the third plate 263 of the present invention is provided with a baffle 290 extending toward the inner wall of the grinding cylinder 210, and the baffle 290 is close to the end of the grinding cylinder; there are two sets of baffles 290 and the two sets of baffles are symmetrically positioned.

[0069] In this invention, the baffle 290 is preferably an arc-shaped baffle, and when the baffle 290 on the third plate 263 of the four grinding parts 260 of this invention is combined with each other, it forms an annular baffle. On the one hand, it reduces the material from escaping from the gap, and on the other hand, it can concentrate the grinding material between the two annular baffles, so that the grinding material can enter the extraction cylinder from the discharge port in the later stage.

[0070] The extraction unit 300 in this application includes an inlet 320, an outlet 330, an extraction cylinder 310, an ultrasonic vibration source 340, and a vibration head 350; according to Figures 1-6The diagram illustrates that the extraction cylinder 310 is located on the second support plate 140, the liquid inlet 320 is located at the top of the extraction cylinder 310, and the liquid outlet 330 is located on the side wall of the extraction cylinder 310 and near the bottom of the extraction cylinder 310; the ultrasonic vibration source 340 is located on the extraction cylinder 310, and the vibration head 350 is located in the extraction cylinder 310 and connected to the ultrasonic vibration source 340 (the connection relationship is not shown in the figure). In this invention, the solvent used for extracting the effective components from the anesthetic plants and the ground material are both input into the extraction cylinder through the liquid inlet; in this invention, by connecting the discharge port 230 with the liquid inlet 320, the ground anesthetic plants can be input into the extraction cylinder 310.

[0071] In addition, to avoid the solvent temperature in the extraction cylinder 310 from getting too high during ultrasonic extraction, a condenser tube 360 ​​is installed on the outer bottom wall of the extraction cylinder 310. The condenser tube 360 ​​is coiled on the outer bottom wall of the extraction cylinder 310. In this invention, external condensed water is introduced into the condenser tube to cool the extraction cylinder 310, thereby avoiding the temperature in the extraction cylinder from getting too high.

[0072] A second aspect of the present invention provides an extraction method for extracting anesthetic plants using the equipment described in the first aspect, comprising the following steps:

[0073] Step 1: Add the powdered anesthetic plant into the grinding cylinder and perform three-stage grinding of the anesthetic plant, including first-stage grinding of the anesthetic plant by connecting the first connecting block and the support, second-stage grinding of the anesthetic plant by connecting the second connecting block and the support, and third-stage grinding of the anesthetic plant by connecting the third connecting block and the support.

[0074] Step 2: Input the anesthetic plant that has undergone three-stage grinding into an extraction tube containing solvent, start the ultrasonic vibration source to extract the active ingredients from the anesthetic plant in the extraction tube, and obtain the extract after filtration.

[0075] Step 3: Separate the extract by column chromatography using macroporous adsorption resin to obtain the active ingredients.

[0076] In this invention, the particle size of the anesthetic plant in step 1 is 0.5-1.0 mm; the solvent in step 2 is ethanol; and elution is performed with ethanol in step 3.

[0077] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. An apparatus for extracting narcotic plants, characterized by, include: Bracket (100); The grinding unit (200) includes a grinding cylinder (210) with an inlet and an outlet and located on a support, a rotating shaft (240) arranged along the axis of the grinding cylinder and connected to the support, and a motor (250) located at one end of the rotating shaft; grinding parts (260) distributed around the rotating shaft, the grinding parts being movably connected to the rotating shaft via a connector (270), and locking parts (280) located at both ends of the grinding parts and connected to the rotating shaft. The grinding component includes a first plate (261), a second plate (262) and a third plate (263) arranged radially along the rotation axis, the first plate being close to the rotation axis, and a grinding structure (264) located on the third plate. The grinding structure (264) includes a connecting post (1) distributed on the third plate (263), one end of the connecting post (1) extending toward the inner wall of the grinding cylinder (210), and a grinding plate (2) located at the extended end of the connecting post (1). The connector (270) includes a first connecting block (271), a second connecting block (272), and a third connecting block (273) located on the first plate, the second plate, and the third plate respectively, with their lengths increasing sequentially, and a support (274) disposed on the rotating shaft. The first connecting block, the second connecting block, and the third connecting block all extend toward the rotating shaft and are matched with the support. The extension end of the third connecting block passes through the second plate and the first plate in sequence, and the extension end of the second connecting block passes through the first plate. When the grinding piece moves along the axis of the rotating shaft, the first connecting block, the second connecting block, and the third connecting block are connected to the support in sequence. When connecting blocks of different heights are connected to the support, the distance from the third plate to the rotating shaft is different, and the distance between the grinding plate and the inner wall of the grinding cylinder changes. An extraction unit (300) is located on the support (100) and is used to extract the active ingredients from ground anesthetic plants.

2. The apparatus for extracting narcotic plants according to claim 1, wherein The locking component (280) includes a connecting disc (281) sleeved on the rotating shaft (240), a locking block (282) located on the rotating shaft (240), the locking block (282) located outside the grinding cylinder (210), a connecting plate (283) disposed at the ends of the first plate (261), the second plate (262) and the third plate (263), and a through hole (284) located on the connecting disc (281) and matching the locking block (282); wherein, the connecting disc (281) and the locking block (282) are connected by bolts, and the connecting plate (283) and the connecting disc (281) are connected by bolts; The locking blocks (282) are in three groups and are distributed at equal intervals along the axis of the rotation shaft (240). The distance between each group of locking blocks (282) is equal to the distance between the first connecting block (271), the second connecting block (272) and the third connecting block (273).

3. The apparatus for extracting plants for narcotic use according to claim 2, characterized by, The connecting plate (281) has a groove (285) on the side near the grinding cylinder (210), and the connecting plate (283) has a slider (286) that matches the groove (285).

4. The apparatus for extracting narcotic plants according to claim 1, wherein The third plate (263) is provided with a baffle (290) extending toward the inner wall of the grinding cylinder (210), the baffle (290) being close to the end of the grinding cylinder (210); The number of baffles (290) is two sets and the two sets of baffles (290) are symmetrical.

5. The apparatus for extracting plants for narcotic use according to claim 4, wherein The first plate (261), the second plate (262) and the third plate (263) are all arc-shaped and coaxially arranged; the grinding plate (2) is arc-shaped.

6. The apparatus for extracting plants for narcotic use according to claim 5, wherein The extraction unit (300) includes an extraction cylinder (310) located on the support (100) and below the grinding cylinder (210), an inlet (320) and an outlet (330) located on the extraction cylinder (310), an ultrasonic vibration source (340) disposed on the extraction cylinder (310), a vibration head (350) located in the extraction cylinder (310) and connected to the ultrasonic vibration source (340), and a condenser (360) disposed at the bottom of the extraction cylinder (310).

7. The apparatus for extracting plants for narcotic use according to claim 6, wherein The support (100) includes a first support column (110), a second support column (120), and a first support plate (130) and a second support plate (140) connected from top to bottom between the first support column and the second support column; the grinding cylinder (210) is located on the first support plate (130), the extraction cylinder (310) is located on the second support plate (140), and the two ends of the rotating shaft (240) are respectively connected to the first support column (110) and the second support column (120) through bearings.

8. A method for extracting an effective component from a narcotic plant using the narcotic plant extraction apparatus according to any one of claims 1 to 7, characterized by, Includes the following steps: Step 1: Add the powdered anesthetic plant into the grinding cylinder and perform three-stage grinding of the anesthetic plant, including first-stage grinding of the anesthetic plant by connecting the first connecting block and the support, second-stage grinding of the anesthetic plant by connecting the second connecting block and the support, and third-stage grinding of the anesthetic plant by connecting the third connecting block and the support. Step 2: Input the anesthetic plant that has undergone three-stage grinding into an extraction tube containing solvent, start the ultrasonic vibration source to extract the effective components from the anesthetic plant in the extraction tube, and obtain the extract after filtration; Step 3: The extract is subjected to macroporous adsorption resin for adsorption and decolorization, elution, and concentration to obtain the active ingredient.

9. The method of claim 8, wherein, The particle size of the anesthetic plant in step 1 is 0.5~1.0 mm; The solvent in step 2 is ethanol; In step 3, ethanol is used for elution.

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