Inhaled oxygen concentration regulating method and respiratory support equipment

Abstract

A method for adjusting the inhaled oxygen concentration and a respiratory support device are disclosed. The method obtains the blood oxygen data of each current adjustment interval in real time, determines the recommended blood oxygen zone in which each blood oxygen data is located, judges whether the severity of each blood oxygen data satisfies the conditions for triggering the adjustment of the inhaled oxygen concentration in advance, and performs the operation of adjusting the inhaled oxygen concentration when the conditions for triggering the adjustment of the inhaled oxygen concentration in advance are met. In this solution, a response is made as to whether to trigger the adjustment of the inhaled oxygen concentration in advance according to the changes in the severity of the patient's blood oxygen data, thereby achieving the purpose of quickly responding to the adjustment of the inhaled oxygen concentration when the patient's blood oxygen changes rapidly. Also disclosed are a method for adjusting the inhaled oxygen concentration and a respiratory support device. The method obtains the blood oxygen data in real time, and then determines the triggering moment of the inhaled oxygen concentration adjustment operation based on the real-time acquired blood oxygen data, thereby achieving the triggering moment of the inhaled oxygen concentration adjustment operation according to the oxygen content in the patient's current blood, thereby achieving dynamic adjustment of the inhaled oxygen concentration.

Description

Technical Field

[0001] The present application relates to the field of respiratory physiology technology in medical equipment, and in particular to a method for regulating the concentration of inhaled oxygen and a respiratory support device. Background Art

[0002] Ventilators, devices that provide mechanical ventilation to replace a patient's spontaneous breathing, are widely used in various treatments. During ventilator therapy, the fraction of inspired oxygen (FiO2) is a crucial parameter, directly affecting the oxygen content of the patient's inhaled gas, which in turn influences the oxygen content in the patient's alveoli and blood, further impacting tissue oxygenation. Therefore, in actual use, the fraction of inspired oxygen needs to be adjusted based on the patient's specific physiological condition to achieve the target oxygenation level.

[0003] At present, the most common way to adjust the inhaled oxygen concentration is to adjust the inhaled oxygen concentration according to the blood oxygen saturation (SpO2) measured by the pulse oximeter within the adjustment interval. Specifically, the SpO2 is measured in real time by the pulse oximeter. If the SpO2 is lower than a certain limit, the switch of the oxygen valve on the ventilator is automatically controlled to open to adjust the inhaled oxygen concentration. The adjustment interval of this method is usually a fixed interval, which can only cope with situations where the blood oxygen changes are small. It is feasible for patients with relatively stable blood oxygen conditions. However, for patients with unstable blood oxygen conditions, if an acute drop in blood oxygen occurs during the adjustment interval, the existing method cannot respond quickly when adjusting the inhaled oxygen concentration.

[0004] Therefore, there is an urgent need for a regulation solution that can quickly respond to rapid changes in the patient's blood oxygen and adjust the inhaled oxygen concentration. Summary of the Invention

[0005] In view of this, embodiments of the present application provide a method for regulating the inhaled oxygen concentration and a respiratory support device to achieve the purpose of quickly responding to the adjustment of the inhaled oxygen concentration when the patient's blood oxygen changes rapidly.

[0006] To achieve the above objectives, the present invention provides the following technical solutions:

[0007] In a first aspect, the present application discloses a method for regulating the concentration of inhaled oxygen, the method comprising:

[0008] Obtain the blood oxygen data of each adjustment interval in real time and determine the recommended blood oxygen zone where each blood oxygen data is located;

[0009] determining whether the severity of each blood oxygen data satisfies a condition for triggering early adjustment of the inhaled oxygen concentration, where the severity refers to the degree to which the blood oxygen data deviates from the treatment target zone, the condition for triggering early adjustment of the inhaled oxygen concentration including an increasing severity, and the recommended blood oxygen zone and the treatment target zone each corresponding to a pre-divided blood oxygen data range;

[0010] The operation of adjusting the inhaled oxygen concentration is performed in advance if the condition for triggering the adjustment of the inhaled oxygen concentration in advance is met; otherwise, the operation of adjusting the inhaled oxygen concentration is performed normally after the timing of the current adjustment interval ends.

[0011] Optionally, the determining whether the severity of each blood oxygen data satisfies a condition for triggering early adjustment of the inhaled oxygen concentration includes:

[0012] Obtaining a reference blood oxygen partition containing the most severe blood oxygen data within a previous adjustment interval, where the previous adjustment interval and the current adjustment interval are not necessarily the same in duration;

[0013] Comparing in real time the severity of the blood oxygen data acquired within the current adjustment interval and the severity of the blood oxygen data of the reference blood oxygen zone;

[0014] Before the timing of the current adjustment interval ends, the number of blood oxygen data obtained in the current adjustment interval whose severity is greater than the severity of the blood oxygen data of the reference blood oxygen zone exceeds a preset number, and the condition for early triggering the adjustment of the inhaled oxygen concentration is met; otherwise, the condition for early triggering the adjustment of the inhaled oxygen concentration is not met.

[0015] Optionally, the determining whether the severity of each blood oxygen data satisfies a condition for triggering early adjustment of the inhaled oxygen concentration includes:

[0016] Starting from the start time of the current adjustment interval, at every first time duration, determining whether the severity of each acquired blood oxygen data continuously increases, the first time duration being less than the duration of the current adjustment interval;

[0017] If there is a continuous increase, the condition for triggering the adjustment of the inhaled oxygen concentration in advance is met; otherwise, the condition for triggering the adjustment of the inhaled oxygen concentration in advance is not met.

[0018] Optionally, the method further comprises:

[0019] Determine in real time whether the duration of each blood oxygen data in the selected blood oxygen zone is less than or equal to the second duration for a third duration, and the third duration is greater than the second duration and less than or equal to the duration of the current adjustment interval;

[0020] If it has lasted for the third time, the inhaled oxygen concentration is adjusted in advance according to the adjustment strategy corresponding to the uncertain blood oxygen triggering mode. Otherwise, it is continued to determine whether the severity of each blood oxygen data meets the conditions for triggering the adjustment of the inhaled oxygen concentration in advance.

[0021] Optionally, triggering and adjusting the inhaled oxygen concentration according to the adjustment strategy corresponding to the uncertain blood oxygen triggering mode includes:

[0022] The weights of each recommended blood oxygen partition are cumulatively calculated to obtain a total weight, wherein the recommended blood oxygen partitions corresponding to different blood oxygen data ranges have different weights, and the size of the weight is determined by the severity of the blood oxygen data;

[0023] comparing the total weight with a first weight threshold and a second weight threshold, respectively, the first weight threshold being used to indicate an increase in oxygen concentration and a first inhaled oxygen concentration adjustment amount, the second weight threshold being used to indicate a decrease in oxygen concentration and a second inhaled oxygen concentration adjustment amount, the first weight threshold being greater than the second weight threshold;

[0024] If the total weight is greater than or equal to the first weight threshold, determining to increase the first inhaled oxygen concentration adjustment amount;

[0025] If the total weight is less than or equal to the second weight threshold, determining to reduce the second inhaled oxygen concentration adjustment amount;

[0026] If the total weight is less than the first weight threshold and greater than the second weight threshold, an adjustment amount for maintaining the current inhaled oxygen concentration is determined.

[0027] Optionally, after acquiring the blood oxygen data of each current adjustment interval in real time, the method further includes:

[0028] Obtaining associated data affecting the credibility of blood oxygen from the blood oxygen data;

[0029] Determining whether the associated data meets the blood oxygen credibility requirement;

[0030] If the condition is satisfied, the step of determining the blood oxygen partition corresponding to the blood oxygen data is performed;

[0031] If not satisfied, continue to obtain blood oxygen data.

[0032] Optionally, if the associated data includes at least pulse rate and / or perfusion index and / or blood oxygen signal quality, determining whether the associated data meets preset requirements includes:

[0033] determining whether the pulse rate change rate is higher than a pulse rate change rate threshold;

[0034] If the pulse rate change rate is higher than the pulse rate change rate threshold, the pulse rate does not meet the blood oxygen credibility requirement; otherwise, the pulse rate meets the blood oxygen credibility requirement; and / or,

[0035] determining whether the pulse rate is lower than a pulse rate threshold;

[0036] If the pulse rate is lower than the pulse rate threshold, the pulse rate does not meet the blood oxygen credibility requirement; otherwise, the pulse rate meets the blood oxygen credibility requirement; and / or,

[0037] determining whether the perfusion index is lower than a perfusion index threshold;

[0038] If the perfusion index is lower than the perfusion index threshold, the perfusion index does not meet the blood oxygen credibility requirement; otherwise, the perfusion index meets the blood oxygen credibility requirement;

[0039] and / or, determining whether the blood oxygen signal quality is lower than a blood oxygen signal quality threshold;

[0040] If the blood oxygen signal quality is lower than the blood oxygen signal quality threshold, the blood oxygen signal quality does not meet the blood oxygen credibility requirement; otherwise, the blood oxygen signal quality meets the blood oxygen credibility requirement.

[0041] Optionally, also include:

[0042] If it is continuously determined that the associated data does not meet the blood oxygen credibility requirement, and the continuous time exceeds a fourth time, an alarm message for suspending the adjustment of the inhaled oxygen concentration is generated.

[0043] Optionally, the operation of adjusting the inhaled oxygen concentration includes:

[0044] Obtaining a designated blood oxygen partition for the current adjustment interval, where the designated blood oxygen partition refers to a recommended blood oxygen partition containing the most severe blood oxygen data among the blood oxygen partitions determined within the current adjustment interval;

[0045] A blood oxygen change trend is determined based on the designated blood oxygen zone, and the inhaled oxygen concentration is adjusted according to a regulation strategy corresponding to the blood oxygen change trend.

[0046] Optionally, determining the blood oxygen change trend based on the designated blood oxygen zone includes:

[0047] Obtaining the designated blood oxygen partition and a reference blood oxygen partition containing the most severe blood oxygen data within the previous adjustment interval;

[0048] comparing the severity of the blood oxygen data in the designated blood oxygen zone with the severity of the blood oxygen data with the greatest severity contained in the reference blood oxygen zone;

[0049] If the severity of the blood oxygen data in the designated blood oxygen zone tends to increase relative to the severity of the blood oxygen data with the greatest severity included in the reference blood oxygen zone, determining that the blood oxygen change trend in the current adjustment interval is a blood oxygen deterioration trend;

[0050] If the severity of the blood oxygen data in the designated blood oxygen zone tends to decrease relative to the severity of the blood oxygen data with the greatest severity included in the reference blood oxygen zone, determining that the blood oxygen change trend in the current adjustment interval is a blood oxygen improvement trend;

[0051] If the severity of the blood oxygen data in the designated blood oxygen zone is consistent with the severity of the blood oxygen data with the greatest severity included in the reference blood oxygen zone, and the blood oxygen types corresponding to the designated blood oxygen zone and the reference blood oxygen zone are non-severe hypoxia or severe hyperoxia, it is determined that the blood oxygen change trend in the current adjustment interval is a blood oxygen stable trend;

[0052] The blood oxygen type includes at least severe hypoxia, severe hyperoxia, moderate hypoxia, moderate hyperoxia, mild hypoxia, mild hyperoxia and normal state.

[0053] Optionally, if the blood oxygen change trend is a deteriorating trend of blood oxygen, adjusting the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend includes:

[0054] If the blood oxygen deterioration trend leans toward severe hypoxia or severe hyperoxia, the inhaled oxygen concentration is adjusted according to a preset maximum single oxygen concentration adjustment amount, and the duration of the next adjustment interval is changed to a fifth duration. The preset maximum single oxygen concentration adjustment amount is set to a different adjustment amount based on different patient types, and the fifth duration is shorter than the duration of the regular adjustment interval.

[0055] If the blood oxygen deterioration trend does not tend toward severe hypoxia or severe hyperoxia, a first oxygen concentration target adjustment amount is obtained based on an offset amount of the blood oxygen data in the designated blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone, an oxygen concentration change rate of the last adjustment of the inspired oxygen concentration, and the preset maximum single oxygen concentration adjustment amount;

[0056] When the first oxygen concentration target adjustment amount is less than or equal to the preset maximum single oxygen concentration adjustment amount, adjusting the inhaled oxygen concentration with the first oxygen concentration target adjustment amount;

[0057] When the first oxygen concentration target adjustment amount is greater than the preset maximum single oxygen concentration adjustment amount, the inhaled oxygen concentration is adjusted with the preset maximum single oxygen concentration adjustment amount, and the difference between the first oxygen concentration target adjustment amount and the preset maximum single oxygen concentration adjustment amount is used as the remaining adjustment amount and added to the cumulative adjustment amount of the designated blood oxygen zone.

[0058] Optionally, if the blood oxygen change trend is a blood oxygen stabilization trend or a blood oxygen improvement trend, adjusting the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend includes:

[0059] If the offset of the blood oxygen data in the designated blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone becomes smaller or remains unchanged, the preset adjustment amount is added to the adjustment amount of the inhaled oxygen concentration within the adjustment interval when the last blood oxygen change trend was a blood oxygen stabilization trend or a blood oxygen improvement trend to obtain a second oxygen concentration target adjustment amount, and the inhaled oxygen concentration is adjusted based on the second oxygen concentration target adjustment amount, and the second oxygen concentration target adjustment amount is not greater than the preset minimum oxygen concentration adjustment amount.

[0060] Optionally, if the blood oxygen change trend is a stable blood oxygen trend, adjusting the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend includes:

[0061] If the offset of the blood oxygen data in the specified blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone becomes larger, a third oxygen concentration target adjustment amount is obtained based on the offset of the blood oxygen data in the specified blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone and the cumulative adjustment amount of the specified blood oxygen zone, and the inhaled oxygen concentration is adjusted based on the third oxygen concentration target adjustment amount.

[0062] Optionally, if the blood oxygen change trend is a stable blood oxygen trend, adjusting the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend includes:

[0063] If the blood oxygen data in the designated blood oxygen zone is within the blood oxygen data range of the treatment target zone, determine the area where the blood oxygen data is located in the treatment target zone, where the area includes at least a downstream area, a midstream area, and an upstream area;

[0064] If the blood oxygen data is in the downstream area, maintain the current adjustment of the inhaled oxygen concentration;

[0065] If the blood oxygen data is in the midstream range, a first timer is started, and when the first timer ends, the inhaled oxygen concentration is adjusted according to a preset minimum oxygen concentration adjustment amount;

[0066] If the blood oxygen data is in the upstream area, a second timer is started. When the second timer ends, the inhaled oxygen concentration is adjusted according to a preset minimum oxygen concentration adjustment amount, and the second timer is greater than the first timer.

[0067] A second aspect of the present application discloses a respiratory support device, comprising:

[0068] A ventilation device for providing an inhalation gas to a patient through a breathing circuit and a breathing accessory, wherein the inhalation gas is an oxygen-containing gas;

[0069] a processor, the processor being signal-connected to the ventilator to control the flow rate of inhaled gas provided by the ventilator to the patient;

[0070] The processor is further configured to:

[0071] Obtain the blood oxygen data of each adjustment interval in real time and determine the recommended blood oxygen zone where each blood oxygen data is located;

[0072] determining whether the severity of each blood oxygen data satisfies a condition for triggering early adjustment of the inhaled oxygen concentration, where the severity refers to the degree to which the blood oxygen data deviates from the treatment target zone, the condition for triggering early adjustment of the inhaled oxygen concentration including an increasing severity, and the recommended blood oxygen zone and the treatment target zone each corresponding to a pre-divided blood oxygen data range;

[0073] The operation of adjusting the intake oxygen concentration is performed when the condition for triggering the adjustment of the intake oxygen concentration in advance is met; otherwise, the operation of adjusting the intake oxygen concentration is performed normally.

[0074] Optionally, the processor for determining whether the severity of each blood oxygen data satisfies the condition for triggering the adjustment of the inhaled oxygen concentration in advance is specifically configured to:

[0075] Obtaining a reference blood oxygen partition containing blood oxygen data with the greatest severity within a previous adjustment interval, where the previous adjustment interval and the current adjustment interval are not necessarily the same in duration; and comparing in real time the severity of the blood oxygen data obtained within the current adjustment interval with the severity of the blood oxygen data of the reference blood oxygen partition;

[0076] Before the timing of the current adjustment interval ends, the number of blood oxygen data obtained in the current adjustment interval whose severity is greater than the severity of the blood oxygen data of the reference blood oxygen zone exceeds a preset number, and the condition for early triggering the adjustment of the inhaled oxygen concentration is met; otherwise, the condition for early triggering the adjustment of the inhaled oxygen concentration is not met.

[0077] Optionally, the processor for determining whether the severity of each blood oxygen data satisfies the condition for triggering the adjustment of the inhaled oxygen concentration in advance is specifically configured to:

[0078] Starting from the start time of the current adjustment interval, at every first duration, determining whether the severity of the blood oxygen data corresponding to each acquired blood oxygen data continuously increases, the first duration being less than the duration of the current adjustment interval;

[0079] If there is a continuous increase, the condition for triggering the adjustment of the inhaled oxygen concentration in advance is met; otherwise, the condition for triggering the adjustment of the inhaled oxygen concentration in advance is not met.

[0080] Optionally, the processor is further configured to:

[0081] Determine in real time whether the duration of each blood oxygen data in the selected blood oxygen zone is less than or equal to the second duration for a third duration, and the third duration is greater than the second duration and less than or equal to the duration of the current adjustment interval;

[0082] If it has lasted for the third time, the adjustment of the inhaled oxygen concentration is triggered according to the adjustment strategy corresponding to the uncertain blood oxygen triggering mode. Otherwise, it is continued to determine whether the severity of each blood oxygen data meets the conditions for triggering the adjustment of the inhaled oxygen concentration in advance.

[0083] Optionally, the processor for triggering adjustment of the inhaled oxygen concentration according to the adjustment strategy corresponding to the uncertain blood oxygen triggering mode is specifically configured to:

[0084] The weights of each recommended blood oxygen partition are cumulatively calculated to obtain a total weight, wherein the recommended blood oxygen partitions corresponding to different blood oxygen data ranges have different weights, and the size of the weight is determined by the severity of the blood oxygen data;

[0085] comparing the total weight with a first weight threshold and a second weight threshold, respectively, the first weight threshold being used to indicate an increase in oxygen concentration and a first inhaled oxygen concentration adjustment amount, the second weight threshold being used to indicate a decrease in oxygen concentration and a second inhaled oxygen concentration adjustment amount, the first weight threshold being greater than the second weight threshold;

[0086] If the total weight is greater than or equal to the first weight threshold, determining to increase the first inhaled oxygen concentration adjustment amount;

[0087] If the total weight is less than or equal to the second weight threshold, determining to reduce the second inhaled oxygen concentration adjustment amount;

[0088] If the total weight is less than the first weight threshold and greater than the second weight threshold, an adjustment amount for maintaining the current inhaled oxygen concentration is determined.

[0089] Optionally, the processor is further configured to:

[0090] After receiving the various blood oxygen data acquired by the acquisition device, obtain the associated data in the blood oxygen data that affects the blood oxygen credibility; determine whether the associated data meets the blood oxygen credibility requirements; if so, determine the blood oxygen partition corresponding to the blood oxygen data; if not, continue to acquire blood oxygen data.

[0091] Optionally, if the associated data includes at least pulse rate and / or perfusion index and / or blood oxygen signal quality, the processor for determining whether the associated data meets preset requirements is specifically configured to:

[0092] determining whether the pulse rate change rate is higher than a pulse rate change rate threshold;

[0093] If the pulse rate change rate is higher than the pulse rate change rate threshold, the pulse rate does not meet the blood oxygen credibility requirement; otherwise, the pulse rate meets the blood oxygen credibility requirement; and / or,

[0094] determining whether the pulse rate is lower than a pulse rate threshold;

[0095] If the pulse rate is lower than the pulse rate threshold, the pulse rate does not meet the blood oxygen credibility requirement; otherwise, the pulse rate meets the blood oxygen credibility requirement; and / or,

[0096] determining whether the perfusion index is lower than a perfusion index threshold;

[0097] If the perfusion index is lower than the perfusion index threshold, the perfusion index does not meet the blood oxygen credibility requirement; otherwise, the perfusion index meets the blood oxygen credibility requirement;

[0098] and / or, determining whether the blood oxygen signal quality is lower than a blood oxygen signal quality threshold;

[0099] If the blood oxygen signal quality is lower than the blood oxygen signal quality threshold, the blood oxygen signal quality does not meet the blood oxygen credibility requirement; otherwise, the blood oxygen signal quality meets the blood oxygen credibility requirement.

[0100] Optionally, the processor is further configured to:

[0101] If it is continuously determined that the associated data does not meet the blood oxygen credibility requirement, and the continuous time exceeds a fourth time, an alarm message for suspending the adjustment of the inhaled oxygen concentration is generated.

[0102] Optionally, the processor for performing the operation of adjusting the inhaled oxygen concentration is specifically configured to:

[0103] Obtaining a designated blood oxygen partition for the current adjustment interval, where the designated blood oxygen partition refers to a recommended blood oxygen partition containing the most severe blood oxygen data among the blood oxygen partitions determined within the current adjustment interval;

[0104] A blood oxygen change trend is determined based on the designated blood oxygen zone, and the inhaled oxygen concentration is adjusted according to a regulation strategy corresponding to the blood oxygen change trend.

[0105] Optionally, the processor for determining the blood oxygen change trend based on the designated blood oxygen zone is specifically configured to:

[0106] Determining a first blood oxygen type corresponding to the designated blood oxygen zone and a second blood oxygen type corresponding to the reference blood oxygen zone;

[0107] If the first blood oxygen type is severe hypoxia or severe hyperoxia, determining that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend;

[0108] If the first blood oxygen type is more severe than the blood oxygen type indicated by the second blood oxygen type, determining that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend, the blood oxygen type including at least severe hypoxia, severe hyperoxia, moderate hypoxia, moderate hyperoxia, mild hypoxia, mild hyperoxia, and normal state;

[0109] If the first blood oxygen type and the second blood oxygen type are consistent and neither is severe hypoxia or severe hyperoxia, determining that the blood oxygen change trend within the current adjustment interval is a blood oxygen stable trend;

[0110] If the first blood oxygen type tends to improve relative to the blood oxygen type indicated by the second blood oxygen type, it is determined that the blood oxygen change trend within the current adjustment interval is a blood oxygen improvement trend.

[0111] Optionally, if the blood oxygen change trend is a blood oxygen deterioration trend, the processor that adjusts the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend is specifically configured to:

[0112] If the blood oxygen deterioration trend leans toward severe hypoxia or severe hyperoxia, the inhaled oxygen concentration is adjusted according to a preset maximum single oxygen concentration adjustment amount, and the duration of the next adjustment interval is changed to a fifth duration. The preset maximum single oxygen concentration adjustment amount is set to a different adjustment amount based on different patient types, and the fifth duration is shorter than the duration of the regular adjustment interval.

[0113] If the blood oxygen deterioration trend does not tend toward severe hypoxia or severe hyperoxia, a first oxygen concentration target adjustment amount is obtained based on an offset amount of the blood oxygen data in the designated blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone, a blood oxygen change rate during the last adjustment of the inspired oxygen concentration, and the preset maximum single oxygen concentration adjustment amount.

[0114] When the first oxygen concentration target adjustment amount is less than or equal to the preset maximum single oxygen concentration adjustment amount, adjusting the inhaled oxygen concentration with the first oxygen concentration target adjustment amount;

[0115] When the first oxygen concentration target adjustment amount is greater than the preset maximum single oxygen concentration adjustment amount, the inhaled oxygen concentration is adjusted with the preset maximum single oxygen concentration adjustment amount, and the difference between the first oxygen concentration target adjustment amount and the preset maximum single oxygen concentration adjustment amount is used as the remaining adjustment amount and added to the cumulative adjustment amount of the designated blood oxygen zone.

[0116] Optionally, if the blood oxygen change trend is a blood oxygen stabilization trend or a blood oxygen improvement trend, the processor that adjusts the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend is specifically used to:

[0117] If the offset of the blood oxygen data in the designated blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone becomes smaller or remains unchanged, the preset adjustment amount is added to the adjustment amount of the inhaled oxygen concentration within the adjustment interval when the last blood oxygen change trend was a blood oxygen stabilization trend or a blood oxygen improvement trend to obtain a second oxygen concentration target adjustment amount, and the inhaled oxygen concentration is adjusted based on the second oxygen concentration target adjustment amount, and the second oxygen concentration target adjustment amount is not greater than the preset minimum oxygen concentration adjustment amount.

[0118] Optionally, if the blood oxygen change trend is a stable blood oxygen trend, the processor that adjusts the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend is specifically configured to:

[0119] If the offset of the blood oxygen data in the specified blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone becomes larger, a third oxygen concentration target adjustment amount is obtained based on the offset of the blood oxygen data in the specified blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone and the cumulative adjustment amount of the specified blood oxygen zone, and the inhaled oxygen concentration is adjusted based on the third oxygen concentration target adjustment amount.

[0120] Optionally, if the blood oxygen change trend is a stable blood oxygen trend, the processor that adjusts the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend is specifically configured to:

[0121] If the blood oxygen data in the designated blood oxygen zone is within the blood oxygen data range of the treatment target zone, determine the area where the blood oxygen data is located in the treatment target zone, where the area includes at least a downstream area, a midstream area, and an upstream area;

[0122] If the blood oxygen data is in the downstream area, maintain the current adjustment of the inhaled oxygen concentration;

[0123] If the blood oxygen data is in the midstream range, a first timer is started, and when the first timer ends, the inhaled oxygen concentration is adjusted according to a preset minimum oxygen concentration adjustment amount;

[0124] If the blood oxygen data is in the upstream area, a second timer is started. When the second timer ends, the inhaled oxygen concentration is adjusted according to a preset minimum oxygen concentration adjustment amount, and the second timer is greater than the first timer.

[0125] A third aspect of the present application discloses a respiratory support device, comprising:

[0126] A ventilation device for providing an inhalation gas to a patient through a breathing circuit and a breathing accessory, wherein the inhalation gas is an oxygen-containing gas;

[0127] a processor, the processor being signal-connected to the ventilator to control the flow rate of inhaled gas provided by the ventilator to the patient;

[0128] and, obtaining blood oxygen data of the patient in real time, and controlling the ventilation device to periodically perform an inhaled oxygen concentration adjustment operation at a fixed interval based on the blood oxygen data to adjust the oxygen concentration in the inhaled gas;

[0129] The processor is further configured to:

[0130] Determining, within a current inhaled oxygen concentration adjustment cycle, a blood oxygen partition corresponding to the real-time acquired blood oxygen data of the patient; the blood oxygen partition is pre-divided according to blood oxygen saturation and includes a treatment target partition;

[0131] Determining a blood oxygen change trend of the patient according to the blood oxygen zones corresponding to the real-time blood oxygen data of the patient;

[0132] When it is determined that the patient's blood oxygen change trend deviates from the treatment target zone, an inhaled oxygen concentration adjustment operation is performed in advance to adjust the patient's blood oxygen level to within the treatment target zone.

[0133] The embodiment of the present application discloses a method for adjusting the inhaled oxygen concentration and a respiratory support device, which obtains each blood oxygen data of the current adjustment interval in real time, determines the recommended blood oxygen zone in which each blood oxygen data is located; judges whether the severity of each blood oxygen data satisfies the condition for triggering the adjustment of the inhaled oxygen concentration in advance, wherein the severity refers to the degree to which the blood oxygen data deviates from the treatment target zone, and the condition for triggering the adjustment of the inhaled oxygen concentration in advance includes that the severity tends to increase, and the recommended blood oxygen zone and the treatment target zone each correspond to a pre-divided blood oxygen data range; performs the adjustment of the inhaled oxygen concentration operation when the condition for triggering the adjustment of the inhaled oxygen concentration in advance is met, otherwise, performs the adjustment of the inhaled oxygen concentration operation normally. In this solution, by responding to whether to trigger the adjustment of the inhaled oxygen concentration in advance according to the change in the severity of the patient's blood oxygen data, the purpose of quickly responding to the adjustment of the inhaled oxygen concentration when the patient's blood oxygen changes rapidly is achieved. BRIEF DESCRIPTION OF THE DRAWINGS

[0134] Figure 1 This is a flow chart of a method for adjusting the inhaled oxygen concentration disclosed in an embodiment of the present application;

[0135] Figure 2This is an example diagram of the division of blood oxygen zones disclosed in an embodiment of the present application;

[0136] Figure 3 A schematic diagram of a process for adjusting the inhaled oxygen concentration disclosed in an embodiment of the present application;

[0137] Figure 4 This is an example diagram of another blood oxygen zoning disclosed in an embodiment of the present application;

[0138] Figure 5 This is an example diagram of another blood oxygen zoning disclosed in an embodiment of the present application;

[0139] Figure 6 A schematic diagram of a process for determining the severity of each blood oxygen data disclosed in an embodiment of the present application;

[0140] Figure 7 This is a schematic diagram of another process for determining the severity of each blood oxygen data disclosed in an embodiment of the present application;

[0141] Figure 8 This is a schematic diagram of a process for adjusting the inhaled oxygen concentration based on adjustment strategy A disclosed in an embodiment of the present application;

[0142] Figure 9 This is a flow chart of another method for adjusting the inhaled oxygen concentration disclosed in an embodiment of the present application;

[0143] Figure 10 This is a schematic diagram of a process for analyzing blood oxygen change trends disclosed in an embodiment of the present application;

[0144] Figure 11 This is a schematic diagram of a blood oxygen trend analysis process under moderate hypoxia disclosed in an embodiment of the present application;

[0145] Figure 12 This is a schematic diagram of a blood oxygen trend analysis process under moderate hyperoxia disclosed in an embodiment of the present application;

[0146] Figure 13 This is a schematic diagram of a blood oxygen trend analysis process under mild hypoxia disclosed in an embodiment of the present application;

[0147] Figure 14 This is a schematic diagram of a blood oxygen trend analysis process under mild hyperoxia disclosed in an embodiment of the present application;

[0148] Figure 15 This is a schematic diagram of a process for adjusting the inhaled oxygen concentration based on adjustment strategy B or C disclosed in an embodiment of the present application;

[0149] Figure 16 A schematic structural diagram of a respiratory support device disclosed in an embodiment of the present application;

[0150] Figure 17 This is a structural schematic diagram of another method for regulating the inhaled oxygen concentration disclosed in an embodiment of the present application. DETAILED DESCRIPTION

[0151] The following will be combined with the drawings in the embodiments of this application to clearly and completely describe the technical solutions in the embodiments of this application. Obviously, the embodiments described are only part of the embodiments of this application, not all of the embodiments. Based on the embodiments in this application, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.

[0152] In this application, relational terms such as first and second are used only to distinguish one feature, entity or operation from another feature, entity or operation, and do not necessarily require or imply any such actual relationship or order between these features, entities or operations. The terms "comprise", "include" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, an element defined by the statement "comprises a ..." does not exclude the presence of other identical elements in the process, method, article or device comprising the element.

[0153] FiO2 (fractional oxygen concentration in the inspired air) is a crucial parameter for patients receiving ventilator therapy. In practice, FiO2 needs to be adjusted based on the patient's specific physiological condition, with the goal of achieving a normal target oxygenation level. In most cases, FiO2 settings are determined empirically by healthcare professionals, using information from relevant oxygenation indicators such as the patient's arterial partial pressure of oxygen (PaO2) or arterial oxygen saturation (SaO2). However, in practice, various issues, such as insufficient hospital staff resources or an excessive number of patients, often prevent healthcare professionals from promptly responding to changes in patient oxygenation and adjusting the inspired oxygen concentration, putting patients at risk of hypoxia or hyperoxia. Prolonged hypoxia can lead to tissue failure, exacerbating the condition and endangering their lives; prolonged hyperoxia can also be harmful. Therefore, it is necessary to enable the ventilator to automatically adjust the inspired oxygen concentration based on the patient's physiological condition when healthcare professionals are unable to be at the patient's bedside to adjust it.

[0154] However, as can be seen from the background art, the existing method of automatically adjusting the inhaled oxygen concentration based on the blood oxygen saturation (SpO2) measured by a pulse oximeter cannot respond quickly when the patient's blood oxygen changes rapidly because it uses a fixed cycle to adjust the inhaled oxygen concentration.

[0155] Therefore, the embodiment of the present application discloses a method for adjusting the inhaled oxygen concentration and a respiratory support device. On the basis of adjusting the inhaled oxygen concentration through a fixed period mentioned above, by setting the conditions for triggering the adjustment of the inhaled oxygen concentration in advance, when the real-time acquired blood oxygen data is in the recommended blood oxygen partition where it is located, and the blood oxygen state corresponding to the recommended blood oxygen partition meets the conditions for triggering the adjustment of the inhaled oxygen concentration in advance, the adjustment of the inhaled oxygen concentration is triggered in advance, and the adjustment strategy corresponding to the blood oxygen change trend within the current adjustment interval is used to adjust the inhaled oxygen concentration. The specific implementation method is described in detail through the following embodiments.

[0156] like Figure 1 FIG. 1 is a flow chart of a method for adjusting the inhaled oxygen concentration disclosed in an embodiment of the present application. The method for adjusting the inhaled oxygen concentration can be applied to various respiratory support devices, such as ventilators, anesthesia machines, etc. The method for adjusting the inhaled oxygen concentration mainly includes the following steps:

[0157] Step 101: Acquire each blood oxygen data of the current adjustment interval in real time, and determine the recommended blood oxygen partition to which each blood oxygen data belongs.

[0158] During the specific implementation of step 101, a pulse oximeter can be used to obtain real-time blood oxygen data. The interval between two inhaled oxygen concentration adjustments is called an adjustment interval. For a fixed interval period, the duration of this interval can be preset based on empirical values. Typically, this adjustment interval is a regular adjustment interval.

[0159] In the embodiment of the present application, blood oxygen saturation can be specifically obtained through blood oxygen data. In actual application, the blood oxygen data obtained in real time can be processed to obtain the blood oxygen saturation used to reflect the blood oxygen data. Both can indicate the oxygen content in the blood.

[0160] In step 101, the blood oxygen partition selected refers to the blood oxygen partition in which the collected blood oxygen data is located. The blood oxygen partition is a partition pre-divided based on the blood oxygen saturation range (blood oxygen data range).

[0161] Before implementing the method for adjusting the inspired oxygen concentration disclosed in the embodiments of the present application, in order to identify the severity of the patient's blood oxygen status based on the degree of deviation from the treatment target zone set by the physician, thereby determining different inspired oxygen concentration adjustments based on the severity; and to determine whether to trigger the inspired oxygen concentration adjustment in advance based on the change in the severity of the blood oxygen status of the patient's blood oxygen zone, it is necessary to divide the overall blood oxygen into several zones. Each zone has a corresponding pre-defined blood oxygen saturation range, or a corresponding pre-defined blood oxygen data range.

[0162] In one embodiment, based on the normal blood oxygen range represented by blood oxygen saturation of 0% to 100%, the area outside the treatment target zone set by the doctor is further divided into at least two block areas. The treatment target zone set by the doctor is used to indicate that the blood oxygen level is in a normal state. It can be understood that the blood oxygen zone includes a treatment target zone, that is, when treating a patient, the patient's corresponding physiological parameters need to be restored to or maintained in the treatment target zone. When the corresponding blood oxygen data (physiological parameters) are in the treatment target zone, it can be considered that the blood oxygen data (physiological parameters) are in a normal state.

[0163] The specific process of dividing blood oxygen zones is as follows:

[0164] Within a blood oxygen saturation range consisting of a first lower limit blood oxygen saturation and a first upper limit blood oxygen saturation, a lower limit blood oxygen saturation of a treatment target zone and an upper limit blood oxygen saturation of the treatment target zone are determined. The region between the first lower limit blood oxygen saturation and the lower limit blood oxygen saturation of the treatment target zone is divided into a hypoxic zone, which is used to indicate that the blood oxygen level is in a hypoxic state. The region between the upper limit blood oxygen saturation of the treatment target zone and the first upper limit blood oxygen saturation is divided into a hyperxic zone, which is used to indicate that the blood oxygen level is in a hyperxic state.

[0165] like Figure 2 The figure shows an example of blood oxygen saturation zones according to an embodiment of the present application. 0% refers to the first lower limit of blood oxygen saturation, 100% refers to the first upper limit of blood oxygen saturation, 87% refers to the lower limit of blood oxygen saturation for the treatment target zone, and 92% refers to the upper limit of blood oxygen saturation for the treatment target zone. Figure 2 90% is the patient's blood oxygen saturation currently being monitored.

[0166] Therefore, the range of treatment target partitions is: [87%, 92%].

[0167] The range of hypoxic zonation was: [0%, 87%).

[0168] The range of peroxozone partitioning is: (92%, 100%).

[0169] Figure 2 This is only an example given in the embodiment of the present application. The division of blood oxygen zones in the embodiment of the present application is not limited to the blood oxygen saturation given above.

[0170] It should be noted that before the inhaled oxygen concentration is adjusted, the recommended blood oxygen zone is constantly updated as the latest blood oxygen data is read.

[0171] In step 101 , each blood oxygen zone corresponds to a blood oxygen state.

[0172] In one embodiment, the blood oxygenation state varies depending on the blood oxygen saturation range corresponding to the blood oxygenation zone. Specifically, the blood oxygenation state corresponding to the treatment target zone is a normal state. The blood oxygenation state corresponding to the hypoxic zone is a hypoxic state. The blood oxygenation state corresponding to the hyperoxic zone is a hyperoxic state.

[0173] Step 102: Determine whether the severity of each blood oxygen data satisfies the condition for triggering the adjustment of the inhaled oxygen concentration in advance. If so, execute step 103; if not, execute step 104.

[0174] In step 102, the severity of the blood oxygen data refers to the degree to which the blood oxygen data deviates from the treatment target partition. The more the blood oxygen data deviates from the treatment target partition, the higher the severity of the blood oxygen data.

[0175] The condition for triggering the adjustment of the inhaled oxygen concentration in advance includes the severity trending up. That is, at least there is a situation where the severity of the blood oxygen data tends to increase, that is, the condition for triggering the adjustment of the inhaled oxygen concentration in advance is met.

[0176] Step 103: Execute the operation of adjusting the inhaled oxygen concentration in advance if the condition for triggering the adjustment of the inhaled oxygen concentration in advance is met.

[0177] Step 104: After the current adjustment interval is over, the operation of adjusting the inhaled oxygen concentration is performed normally.

[0178] The operation of adjusting the inhaled oxygen concentration performed in step 103 and step 104 may optionally be performed by adopting a corresponding adjustment strategy based on a blood oxygen change trend within a current adjustment interval.

[0179] In the embodiment of the present application, the operation of adjusting the inhaled oxygen concentration is as follows: Figure 3 As shown, including:

[0180] Step 301: Obtain a designated blood oxygen partition of the current adjustment interval, where the designated blood oxygen partition refers to a recommended blood oxygen partition containing blood oxygen data with the greatest severity among the blood oxygen partitions determined within the current adjustment interval.

[0181] In step 301, the designated blood oxygen partition of the current adjustment interval refers to the recommended blood oxygen partition containing the blood oxygen data with the greatest severity determined within the current adjustment interval, and is used to indicate the overall blood oxygen partition result within the current adjustment interval.

[0182] In a specific implementation, the severity of the blood oxygen data acquired within the current adjustment interval can be compared at preset time intervals to determine the recommended blood oxygen partition containing the blood oxygen data with the greatest severity as the designated blood oxygen partition. This is done until the inhaled oxygen concentration adjustment operation is triggered in advance or the inhaled oxygen concentration adjustment operation is performed normally, so that the recommended blood oxygen partition containing the blood oxygen data with the greatest severity is finally determined as the designated blood oxygen partition within the current adjustment interval.

[0183] It is also possible to obtain each piece of blood oxygen data in real time and compare the severity of the blood oxygen data with the severity of other obtained blood oxygen data, and determine the designated blood oxygen partition within the current adjustment interval in real time until the operation of adjusting the inhaled oxygen concentration is triggered in advance or the operation of adjusting the inhaled oxygen concentration is performed normally, so as to finally determine that the recommended blood oxygen partition containing the blood oxygen data with the greatest severity is the designated blood oxygen partition within the current adjustment interval.

[0184] Taking real-time comparison as an example, assume that the minimum number of blood oxygen data that can be obtained within the current interval is 20. Starting from entering the current interval, when the first blood oxygen data is obtained, the recommended blood oxygen partition in which the first blood oxygen data is located is determined to be the designated blood oxygen partition in the current adjustment interval. When the second blood oxygen data is obtained, the severity of the second blood oxygen data is compared with the severity of the first blood oxygen data. If the severity of the first blood oxygen data is greater than the severity of the second blood oxygen data, the recommended blood oxygen partition in which the first blood oxygen data is located continues to be the designated blood oxygen partition in the current adjustment interval. The above real-time comparison is continuously performed until the inhaled oxygen concentration adjustment operation is performed in advance or the inhaled oxygen concentration adjustment operation is performed normally, so as to finally determine that the recommended blood oxygen partition containing the blood oxygen data with the greatest severity is the designated blood oxygen partition in the current adjustment interval.

[0185] Step 302: Determine a blood oxygen change trend based on the designated blood oxygen zone, and adjust the inhaled oxygen concentration according to a regulation strategy corresponding to the blood oxygen change trend.

[0186] In step 302 , the blood oxygen change trend includes a blood oxygen deterioration trend, a blood oxygen stabilization trend, and a blood oxygen improvement trend.

[0187] A worsening trend in blood oxygen levels indicates that the patient's blood oxygen levels are further deviating from the treatment target zone.

[0188] The stable blood oxygen trend indicates that the patient's blood oxygen has no obvious trend of changing toward the treatment target partition or deviating from the target blood oxygen range.

[0189] The improving trend of blood oxygen level indicates that the patient's blood oxygen level is moving towards the treatment target zone.

[0190] Then, a corresponding regulation strategy is determined based on the blood oxygen change trend, and the inhaled oxygen concentration is adjusted according to the regulation strategy.

[0191] By performing the operation of adjusting the inhaled oxygen concentration disclosed in the embodiments of the present application, an adjustment strategy for the inhaled oxygen concentration suitable for each patient is determined based on the blood oxygen variation trend of each patient, so that the operation of adjusting the inhaled oxygen concentration disclosed in the embodiments of the present application can be used for patients with different blood oxygen states. This can avoid the drawbacks of the prior art of using a fixed adjustment amount or a fixed adjustment target to adjust the inhaled oxygen concentration for patients with different blood oxygen states. Furthermore, there is no need to distinguish which patients can use the device and which patients cannot use it.

[0192] In the method for adjusting the inspired oxygen concentration disclosed in the embodiments of the present application, a response is made to whether to trigger early adjustment of the inspired oxygen concentration based on the severity of changes in the patient's blood oxygen data. If early adjustment of the inspired oxygen concentration is determined, the inspired oxygen concentration is adjusted promptly based on an adjustment strategy corresponding to the blood oxygen change trend within the current adjustment interval. This achieves the goal of quickly responding to rapid changes in the patient's blood oxygen level and adjusting the inspired oxygen concentration.

[0193] Based on the above embodiments of the present application Figure 1 In the disclosed method for regulating the inhaled oxygen concentration, in step 101, the blood oxygen zones are divided into treatment target zones, hypoxia zones, and hyperoxia zones.

[0194] The treatment target area can also be further divided. Specifically, the treatment target area can be divided into multiple areas. Preferably, Figure 4 As shown, the treatment target area can be divided into a downstream area, a midstream area and an upstream area. However, the division of the treatment target area in the embodiment of the present application is not limited to three areas.

[0195] In addition, the treatment target zoning can be performed in equal proportions or in unequal proportions.

[0196] In one embodiment, the hypoxic zones may be further divided. Specifically:

[0197] First, a first boundary blood oxygen saturation and a second boundary blood oxygen saturation of the hypoxic zone are determined, wherein the first boundary blood oxygen saturation is less than the lower limit blood oxygen saturation of the treatment target zone, and the first boundary blood oxygen saturation is greater than the second boundary blood oxygen saturation.

[0198] Then, the area between the lower limit blood oxygen saturation of the treatment target zone and the first boundary blood oxygen saturation is divided into a mild hypoxia zone, and the mild hypoxia zone is used to indicate that the blood oxygen level is in a mild hypoxia state.

[0199] The area between the first boundary blood oxygen saturation and the second boundary blood oxygen saturation is divided into a moderate hypoxia zone, and the moderate hypoxia zone is used to indicate that the blood oxygen level is in a moderate hypoxia state.

[0200] The area between the second boundary blood oxygen saturation and the first lower limit blood oxygen saturation is divided into a severe hypoxia zone, and the severe hypoxia zone is used to indicate that the blood oxygen level is in a severe hypoxia state.

[0201] It should be noted that there are many ways to determine the first boundary blood oxygen saturation and the second boundary blood oxygen saturation of the hypoxic zone.

[0202] The first method is to obtain the blood oxygen saturation range contained in the treatment target partition; calculate based on the blood oxygen saturation range contained in the treatment target partition, the first lower limit blood oxygen saturation and the lower limit blood oxygen saturation of the treatment target partition to determine the first boundary blood oxygen saturation and the second boundary blood oxygen saturation.

[0203] The second method: obtaining the blood oxygen saturation and blood oxygen alarm limit range contained in the treatment target partition; calculating based on the blood oxygen saturation contained in the treatment target partition, the blood oxygen alarm limit range, the first lower limit blood oxygen saturation and the lower limit blood oxygen saturation of the treatment target partition to determine the first boundary blood oxygen saturation and the second boundary blood oxygen saturation.

[0204] The third method: obtaining a first historical blood oxygen saturation corresponding to a moderate hypoxic state and a second historical blood oxygen saturation corresponding to a severe hypoxic state; determining a first boundary blood oxygen saturation based on the first historical blood oxygen saturation, and determining a second boundary blood oxygen saturation based on the second historical blood oxygen saturation.

[0205] Combine Figure 2 , Figure 5 The first boundary blood oxygen saturation of the hypoxic zone is given as 84%, and the second boundary blood oxygen saturation of the hypoxic zone is given as 81%.

[0206] Thus, the range of mild hypoxia zone was: [84%, 87%).

[0207] The range of moderate hypoxia zones was: [81%, 84%).

[0208] The range of severe hypoxia zones was: [0%, 81%).

[0209] In one embodiment, the peroxygen zone can be further divided. Specifically:

[0210] First, a third boundary blood oxygen saturation and a fourth boundary blood oxygen saturation are determined. The third boundary blood oxygen saturation is greater than the upper limit blood oxygen saturation of the treatment target zone, and the third boundary blood oxygen saturation is less than the fourth boundary blood oxygen saturation.

[0211] Then, the area between the upper limit of the blood oxygen saturation of the treatment target zone and the third boundary blood oxygen saturation is defined as a mild hyperoxic zone, and the mild hyperoxic zone is used to indicate that the blood oxygen level is in a mild hyperoxic state.

[0212] The area between the third boundary blood oxygen saturation and the fourth boundary blood oxygen saturation is defined as a moderate hyperoxygen zone, and the moderate hyperoxygen zone is used to indicate that the blood oxygen level is in a moderate hyperoxygen state.

[0213] The area between the fourth boundary blood oxygen saturation and the first upper limit blood oxygen saturation is defined as a severe hyperoxia zone, and the severe hyperoxia zone is used to indicate that the blood oxygen level is in a severe hyperoxia state.

[0214] It should be noted that there are many ways to determine the third boundary blood oxygen saturation and the fourth boundary blood oxygen saturation of the hypoxic zone.

[0215] The first method is to obtain the blood oxygen saturation range contained in the treatment target partition; calculate based on the blood oxygen saturation range contained in the treatment target partition, the first upper limit blood oxygen saturation and the upper limit blood oxygen saturation of the treatment target partition to determine the third boundary blood oxygen saturation and the fourth boundary blood oxygen saturation.

[0216] The second method: obtaining the blood oxygen saturation and blood oxygen alarm limit range contained in the treatment target partition; calculating based on the blood oxygen saturation contained in the treatment target partition, the blood oxygen alarm limit range, the first upper limit blood oxygen saturation and the upper limit blood oxygen saturation of the treatment target partition to determine the third boundary blood oxygen saturation and the fourth boundary blood oxygen saturation.

[0217] The third method: obtaining a third historical blood oxygen saturation corresponding to a moderate hyperoxia state and a fourth historical blood oxygen saturation corresponding to a severe hyperoxia state; determining a third boundary blood oxygen saturation based on the third historical blood oxygen saturation, and determining a fourth boundary blood oxygen saturation based on the fourth historical blood oxygen saturation.

[0218] Combine Figure 2 , Figure 5 The third boundary blood oxygen saturation of the hyperoxic zone is given as 94%, and the fourth boundary blood oxygen saturation of the hypoxic zone is given as 96%.

[0219] Thus, the range of the mild hyperoxia zone is: (92%, 94%).

[0220] The range of moderate hyperoxic zone is: (94%, 96%).

[0221] The range of the severe hyperoxic zone is: (96%, 100%).

[0222] In the embodiment of the present application, the severity of the patient's blood oxygen status is identified by dividing the blood oxygen zone into zones according to the degree of deviation from the target blood oxygen range. Therefore, when the inhaled oxygen concentration adjustment operation is subsequently performed, different adjustment strategies can be determined based on the severity of the blood oxygen status corresponding to the blood oxygen zone, and whether to trigger the inhaled oxygen concentration adjustment operation in advance can be determined based on the change in the blood oxygen status of the blood oxygen zone where the patient's blood oxygen data is located.

[0223] Furthermore, depending on the severity, a higher severity blood oxygen status adopts a higher inhaled oxygen concentration adjustment amount and a shorter adjustment interval, thereby achieving an effect in which the inhaled oxygen concentration adjustment intensity increases in a step-by-step manner as the severity of the patient's blood oxygen status increases.

[0224] Based on the above embodiments of the present application Figure 1 In the disclosed method for adjusting the inhaled oxygen concentration, in step 102, the severity of each blood oxygen data can be analyzed in various ways to determine in real time whether the severity of the blood oxygen data meets the conditions for triggering the adjustment of the inhaled oxygen concentration in advance.

[0225] The embodiment of the present application provides the following three methods, but the embodiment of the present application is not limited to the following three methods for determining the severity of each blood oxygen data.

[0226] The first method is:

[0227] Obtain a reference blood oxygen partition containing the blood oxygen data with the greatest severity in the previous adjustment interval, and compare in real time the severity of the blood oxygen data obtained in the current adjustment interval with the severity of the blood oxygen data in the reference blood oxygen partition; before the end of the timing of the current adjustment interval, if the number of times the severity of the blood oxygen data obtained in the current adjustment interval is greater than the severity of the blood oxygen data in the reference blood oxygen partition exceeds a preset number, the condition for triggering the early adjustment of the inhaled oxygen concentration is met; otherwise, the condition for triggering the early adjustment of the inhaled oxygen concentration is not met.

[0228] It should be noted that the duration of the previous adjustment interval and the current adjustment interval are not necessarily the same.

[0229] In one embodiment, the specific implementation process of the first method is as follows: Figure 6 As shown, the following steps are included:

[0230] Step 601: Determine a reference blood oxygen partition containing the blood oxygen data with the greatest severity within the last adjustment interval.

[0231] The reference blood oxygen partition containing the blood oxygen data with the greatest severity within the previous adjustment interval determined in step 601 is the overall blood oxygen partition result within the previous adjustment interval.

[0232] The overall blood oxygen zoning result within the previous adjustment interval refers to the overall blood oxygen zoning when the inhaled oxygen concentration adjustment operation is performed within the previous adjustment interval or after the previous adjustment interval. The overall blood oxygen zoning is used to represent the overall blood oxygen status within the previous adjustment interval.

[0233] Specifically, when the blood oxygen data acquired during an adjustment interval correspond to different blood oxygen zones, it is necessary to evaluate an overall blood oxygen zone to summarize the "more important blood oxygen zone events" within the adjustment interval. In other words, the blood oxygen zone corresponding to the most severe blood oxygen state is used as a reference blood oxygen zone for subsequent use.

[0234] For example, if the blood oxygen data acquired within a certain adjustment interval includes both blood oxygen data corresponding to a "treatment target zone" and blood oxygen data corresponding to an "overoxygen zone," the "overoxygen zone" is considered the "more important blood oxygen zone event." This "overoxygen zone" is used as a reference blood oxygen zone for subsequent use. Of course, in other embodiments, different strategies can be used to determine the overall blood oxygen status within a certain adjustment interval.

[0235] The following steps are executed cyclically in the current interval until it is determined whether the severity of each blood oxygen data acquired in the current adjustment interval triggers the condition for adjusting the inhaled oxygen concentration in advance.

[0236] Step 602: Determine whether the current adjustment interval has expired. If so, determine that the condition for triggering the adjustment of the inhaled oxygen concentration in advance is not met. If not, obtain the next blood oxygen data and execute step 603.

[0237] Step 603: Compare the severity of the currently acquired blood oxygen data with the severity of the blood oxygen data of the reference blood oxygen partition. If the severity of the currently acquired blood oxygen data is greater than the severity of the blood oxygen data of the reference blood oxygen partition, execute step 604; if the severity of the currently acquired blood oxygen data is not greater than the severity of the blood oxygen data of the reference blood oxygen partition, execute step 605.

[0238] While executing step 603 , it may also be determined that, based on the currently acquired blood oxygen data, the recommended blood oxygen partition containing the blood oxygen data with the greatest severity is the designated blood oxygen partition within the current adjustment interval.

[0239] Specifically, the severity of each currently acquired blood oxygen data point is compared to determine the recommended blood oxygen zone containing the most severe blood oxygen data point, which is then designated as the designated blood oxygen zone. This can be understood as evaluating an overall blood oxygen zone to summarize the "more important blood oxygen zone events" within the adjustment interval.

[0240] Step 604: Accumulate the number of blood oxygen data acquired within the current adjustment interval whose severity is greater than the severity of the blood oxygen data of the reference blood oxygen zone.

[0241] Step 605: Determine whether the current accumulated number exceeds the preset number. If so, the condition for triggering the inhaled oxygen concentration in advance is met; if not, execute step 602.

[0242] In step 605, the severity of the blood oxygen data obtained in the current accumulated adjustment interval is judged to be greater than the severity of the blood oxygen data of the reference blood oxygen zone, to determine whether the severity of the blood oxygen data has increased compared with the previous adjustment interval, and whether the change is an accidental event. If the current accumulated number does not exceed the preset number, it means that it may be an accidental event, or in other words, it has not reached the level of triggering the adjustment of the inhaled oxygen concentration in advance, then return to step 602 to continue to determine whether the timing of the current adjustment interval has ended. If it has ended, it means that it is in a normal state of adjusting the inhaled oxygen concentration. If it has not ended, continue to obtain the next blood oxygen data. If the current accumulated number exceeds the preset number, it means that before the timing of the current interval has ended, it has reached the level of triggering the adjustment of the inhaled oxygen concentration in advance, and the conditions for triggering the inhaled oxygen concentration in advance are met.

[0243] Assume that the preset number is 15. If the current accumulated number is 16, the condition for triggering the inhaled oxygen concentration in advance is met.

[0244] In the specific implementation of step 605, the judgment is made based on the number of blood oxygen data acquired in the current adjustment interval accumulated in step 604 whose severity is greater than the severity of the blood oxygen data of the reference blood oxygen partition.

[0245] By using the accumulated number, it is determined whether the overall blood oxygen status of the current adjustment interval has changed compared with the reference blood oxygen partition determined in the previous adjustment interval. If the number of blood oxygen data acquired in the current adjustment interval whose severity is greater than the severity of the blood oxygen data of the reference blood oxygen partition is greater than the preset number, it indicates that the patient's blood oxygen status may have deteriorated and requires high attention. The operation of adjusting the inhaled oxygen concentration can be triggered in advance.

[0246] If the number of blood oxygen data points acquired within the current adjustment interval whose severity is greater than the severity of the blood oxygen data points of the reference blood oxygen zone is no greater than a preset number, it indicates that the patient's blood oxygen status may be improving or maintaining the blood oxygen status trend corresponding to the blood oxygen zone of the previous adjustment interval. However, because the current adjustment interval has not yet expired, the next blood oxygen data point is acquired and the assessment is continued until it is determined that the inhaled oxygen concentration adjustment operation can be triggered in advance or the timer expires, and the inhaled oxygen concentration adjustment operation is performed normally.

[0247] It should be noted that, according to different methods of determining the designated blood oxygen zone of the current adjustment interval, the designated blood oxygen zone of the current adjustment interval can be determined in real time while executing step 603, or the designated blood oxygen zone of the current adjustment interval can be determined after the current adjustment interval timing ends or within a preset time period.

[0248] Optionally, the technical solution for determining whether the current accumulated number exceeds the preset number in step 605 can also be implemented by determining the percentage of the severity of the currently acquired blood oxygen data that is greater than the severity of the blood oxygen data of the reference blood oxygen partition. Specifically, based on the total number N of blood oxygen data that can be acquired in the current adjustment interval and the number n of currently acquired blood oxygen data with a severity greater than that of the reference blood oxygen partition, a percentage K is calculated based on formula (1). It is determined whether the percentage exceeds the preset percentage. If so, the condition for triggering the inhaled oxygen concentration in advance is met; if not, step 602 is executed.

[0249] K=n / N (1)

[0250] Assume that the minimum number of blood oxygen data that can be obtained in the current interval is 20, and the preset proportion is 60%. Through real-time comparison, if the current accumulated number is 10, the proportion K = 50%. This proportion K is less than 60%, and the condition for triggering the inhaled oxygen concentration in advance is not met. If the current accumulated number is 13, the proportion K = 65%. This proportion K is greater than 60%, and the condition for triggering the inhaled oxygen concentration in advance is met.

[0251] The second method is:

[0252] Starting from the start time of the current adjustment interval, at intervals of a first duration, it is determined whether the severity of each acquired blood oxygen concentration data point continuously increases; if so, the condition for triggering early adjustment of the inhaled oxygen concentration is met; otherwise, the condition for triggering early adjustment of the inhaled oxygen concentration is not met. The first duration is less than the duration of the current adjustment interval and can be an empirical value.

[0253] That is to say, if the blood oxygen data changes continuously in a short period of time in a direction that deviates from the treatment target partition, the conditions for triggering the operation of adjusting the inhaled oxygen concentration in advance are also met.

[0254] For example, assuming the first duration is 30 seconds, if the blood oxygen data is in the hypoxia zone for the previous 30 seconds, and after 30 seconds, it continues to deviate from the treatment target zone, the severity increases. After another 30 seconds, it continues to deviate from the treatment target zone, and the severity continues to increase. At this time, the conditions for triggering the early adjustment of the inhaled oxygen concentration operation are met.

[0255] The third method is:

[0256] Determine in real time whether the duration of each blood oxygen data in the recommended blood oxygen zone is less than or equal to the second duration; if it is less than or equal to the second duration, then determine whether the situation in which the duration of each blood oxygen data in the recommended blood oxygen zone is less than or equal to the second duration has continued for a third duration; if it has continued for the third duration, trigger the adjustment of the inhaled oxygen concentration in advance according to the adjustment strategy corresponding to the uncertain blood oxygen triggering method, otherwise continue to determine whether the severity of each blood oxygen data meets the conditions for triggering the adjustment of the inhaled oxygen concentration in advance.

[0257] The third duration is greater than the second duration and less than or equal to the duration of the current adjustment interval.

[0258] In one embodiment, half the duration of the regular adjustment interval may be used as the third duration.

[0259] For example, assuming that the current adjustment interval is 120 seconds, the third time is 60 seconds, and the second time is 15 seconds. If the hypoxia zone is further divided into mild hypoxia zone, moderate hypoxia zone and severe hypoxia zone. When the blood oxygen data is in the mild hypoxia zone, but the duration in the mild hypoxia zone does not exceed 15 seconds, it further deviates from the treatment target zone and moves to the moderate hypoxia zone. Similarly, the duration in the moderate hypoxia zone does not exceed 15 seconds, and it shifts back to the mild hypoxia zone. This situation continues for more than 60 seconds. At this time, it can be determined that the current blood oxygen status cannot be determined, and it is necessary to trigger the adjustment of the inhaled oxygen concentration in advance according to the adjustment strategy corresponding to the uncertain blood oxygen triggering method.

[0260] In one embodiment, the specific implementation process of the third method is as follows: Figure 7 As shown, the following steps are included:

[0261] Step 701: Determine in real time whether the duration of the currently acquired blood oxygen data in the recommended blood oxygen zone is less than or equal to the second duration. If not, reset the duration timer and execute step 702; if so, execute step 706.

[0262] Step 702: Determine whether the current adjustment interval has expired. If so, determine that the condition for triggering the adjustment of the inhaled oxygen concentration in advance is not met. If not, obtain the next blood oxygen data and execute step 703.

[0263] Step 703: Compare the severity of the currently acquired blood oxygen data with the severity of the blood oxygen data of the reference blood oxygen partition. If the severity of the currently acquired blood oxygen data is greater than the severity of the blood oxygen data of the reference blood oxygen partition, execute step 704; if the severity of the currently acquired blood oxygen data is greater than the severity of the blood oxygen data of the reference blood oxygen partition, execute step 705.

[0264] While executing step 703 , it is also possible to determine, based on the currently acquired blood oxygen data, that the recommended blood oxygen partition containing the blood oxygen data with the greatest severity is the designated blood oxygen partition within the current adjustment interval.

[0265] Step 704: Accumulate the number of blood oxygen data acquired within the current adjustment interval whose severity is greater than the severity of the blood oxygen data of the reference blood oxygen zone.

[0266] Step 705: Determine whether the current accumulated number exceeds the preset number. If so, the condition for triggering the inhaled oxygen concentration in advance is met; if not, execute step 702.

[0267] Step 706: Continue timing and determine whether the duration of the continuous timing exceeds the third duration. If so, execute step 707; if not, execute step 701.

[0268] In step 706, it is determined whether the duration of the continuous timing exceeds the third duration. This is because if the blood oxygen data is continuously obtained in the current adjustment interval for a duration less than or equal to the second duration in the selected blood oxygen zone, it means that the patient's blood oxygen fluctuations may be larger and more frequent at this time, and the blood oxygen zone may change repeatedly. Therefore, it is necessary to perform a blood oxygen uncertainty judgment, that is, to determine whether the blood oxygen data in the selected blood oxygen zone is less than or equal to the second duration for the third duration. If so, it means that blood oxygen uncertainty occurs in the current adjustment interval, and the inhaled oxygen concentration also needs to be adjusted at this time.

[0269] Step 707: Adjust the inhaled oxygen concentration according to the adjustment strategy A corresponding to the uncertain blood oxygen triggering mode.

[0270] Specifically, step 707 is implemented as follows: Figure 8 As shown, the following steps are included:

[0271] Step 801: Accumulate and calculate the weights of each recommended blood oxygen partition to obtain a total weight.

[0272] In step 801, the divided blood oxygen zones are assigned values in advance, and each blood oxygen zone is assigned a weight coefficient. Blood oxygen zones corresponding to different blood oxygen states have different weights, and the size of the weight is determined by the severity of the blood oxygen data.

[0273] For example, if the complete blood oxygen is divided into a treatment target zone, a severe hypoxia zone, a moderate hypoxia zone, a mild hypoxia zone, a severe hyperoxia zone, a moderate hyperoxia zone, and a mild hyperoxia zone.

[0274] The mild hypoxia zone, moderate hypoxia zone, and severe hypoxia zone can be assigned weights of +1, +2, and +3 respectively, and the mild hyperoxia zone, moderate hyperoxia zone, and severe hyperoxia zone can be assigned weights of -1, -2, and -3 respectively. The zones within the treatment target zone do not participate in the cumulative zone (or the cumulative weight is 0).

[0275] Based on the above example, if the recommended blood oxygen zones determined within the current adjustment interval are two mild hypoxia zones, two treatment target zones, and one moderate hypoxia zone, step 701 is executed to determine the cumulative weights of each blood oxygen zone, and the total weight obtained is: 4.

[0276] It should be noted that the time required to perform step 801 to cumulatively calculate the weights of each selected blood oxygen partition and obtain the total weight is the time required to perform step 801 to cumulatively calculate the weights of each selected blood oxygen partition and obtain the total weight. Figure 7 The time recorded by the first timing exceeding the third duration in step 706 is executed.

[0277] For example, if the time recorded by the first timer exceeding the third time period in step 706 is 20 seconds, the accumulated weights of the recommended blood oxygen zones are the weights of the recommended blood oxygen zones in which the blood oxygen data acquired within these 20 seconds is located.

[0278] Step 802: Compare the total weight with the first weight threshold and the second weight threshold, respectively. If the total weight is greater than or equal to the first weight threshold, proceed to step 803; if the total weight is less than or equal to the second weight threshold, proceed to step 804; if the total weight is less than the first weight threshold but greater than the second weight threshold, proceed to step 805.

[0279] In step 802, the first weight threshold is used to indicate an increase in oxygen concentration and a first inhaled oxygen concentration adjustment amount, and the second weight threshold is used to indicate a decrease in oxygen concentration and the second inhaled oxygen concentration adjustment amount. The first weight threshold is greater than the second weight threshold.

[0280] It should be noted that the first inhaled oxygen concentration adjustment amount indicated by the first weight threshold may be any adjustment amount between 1% and 5%, but is not limited to this range.

[0281] The second intake oxygen concentration adjustment amount indicated by the second weight threshold can be any adjustment amount between -1% and -5%, but is not limited to this range.

[0282] Step 803: Determine to increase the first inhaled oxygen concentration adjustment amount.

[0283] Step 804: Determine to reduce the second inhaled oxygen concentration adjustment amount.

[0284] Step 805: Determine to maintain the current inhaled oxygen concentration.

[0285] For example, assuming the first weight threshold is 10, the first inhaled oxygen concentration adjustment indicated by the first weight threshold is 1%. The second weight threshold is -10, the second inhaled oxygen concentration adjustment indicated by the second weight threshold is -1%, and the time used to determine whether the blood oxygen level within the adjustment interval is uncertain is 20 seconds.

[0286] If the recommended blood oxygen concentration zones for the blood oxygen data acquired within 20 seconds are 4 moderate hypoxia zones and 2 severe hypoxia zones, the accumulated total weight is (4*2)+(2*3)=14. This total weight is greater than the first weight threshold, indicating that the oxygen concentration needs to be increased by 1%.

[0287] If the recommended blood oxygen concentration zones for the blood oxygen data acquired within 20 seconds are 2 moderate hyperoxia zones and 4 severe hyperoxia zones, the accumulated total weight is (2*-2)+(4*-3)=16. This total weight is less than the second weight threshold, indicating that the oxygen concentration needs to be reduced by 1% (-1%).

[0288] If the recommended blood oxygen zones for the blood oxygen data acquired within 20 seconds are four treatment target zones and two mild hypoxia zones, the accumulated total weight is (4*0)+(2*1)=2. If this total weight is less than the first weight threshold and greater than the second weight threshold, the current inspired oxygen concentration is maintained.

[0289] It should be noted that the embodiment of the present application only provides the case of setting two weight thresholds. In a specific implementation, multiple weight thresholds can be set based on the blood oxygen zone type, and different oxygen concentration adjustment amounts can be set according to different weight thresholds. The weights corresponding to the selected blood oxygen zones determined in the case of uncertain blood oxygen within the adjustment interval are then accumulated, and the accumulated results are compared with the multiple weight thresholds, and different oxygen concentration adjustment amounts are selected based on the comparison.

[0290] For example, based on six blood oxygenation zones (severe hypoxia, moderate hypoxia, mild hypoxia, severe hyperoxia, moderate hyperoxia, and mild hyperoxia), six weighted thresholds are set: 30, 20, 10, -10, -20, and -30. The corresponding oxygen concentration adjustments are 3%, 2%, 1%, -1%, -2%, and -3%, respectively. Positive values indicate increased oxygenation, while negative values indicate decreased oxygenation.

[0291] If the recommended blood oxygen concentration zone of the blood oxygen data within the 20-second interval used to determine the uncertainty of the blood oxygen level within the adjustment interval frequently changes and cannot be stabilized in a single zone, and the calculated total weight is greater than or equal to 30, it indicates that at least half of the blood oxygen data is in the severe hypoxia zone. In this case, a 3% oxygen concentration adjustment is made, and the adjustment direction is to increase oxygen. If the calculated total weight is between 20 and 30, it indicates that the current blood oxygen data is mainly concentrated in the moderate hypoxia zone. In this case, a 2% oxygen concentration adjustment is made, and the adjustment direction is to increase oxygen. Similarly, when the total weight is negative, the adjustment direction is to reduce oxygen. Different oxygen concentration adjustment amounts and adjustment directions are made based on the comparison between the total weight and the weight threshold. When the calculated total weight is between -10 and 10, the current inhaled oxygen concentration is maintained and no oxygen concentration adjustment is made.

[0292] Through the above approach, when a patient's blood oxygen data is outside the treatment target zone, even if the patient's blood oxygen data fluctuates frequently and the blood oxygen trend is unclear, the oxygen concentration adjustment amount and direction can still be determined based on the blood oxygen zone in which all blood oxygen data within the adjustment interval are located. Furthermore, when the calculated total weight is between -10 and 10, it indicates that less than half of the blood oxygen data has deviated from the treatment target zone, but the degree of deviation is relatively small. Therefore, when such a small, short-term deviation from the treatment target zone occurs, the current inspired oxygen concentration can be maintained without excessive adjustment of the inspired oxygen concentration.

[0293] In this embodiment of the present application, when the blood oxygen zoning is uncertain, adjustment strategy A is used to first calculate the cumulative weights of the blood oxygen zoning determined within the current adjustment interval, and then determine the adjustment direction and amount of the inspired oxygen concentration based on this cumulative result. This completes the adjustment of the inspired oxygen concentration.

[0294] In the above Figure 1 Based on the method for adjusting the inhaled oxygen concentration disclosed in the embodiment of the present application, the embodiment of the present application also discloses another method for adjusting the inhaled oxygen concentration, such as Figure 9 As shown, the method for adjusting the inhaled oxygen concentration includes the following steps:

[0295] Step 901: Determine whether valid blood oxygen data is obtained in the current adjustment interval. If no blood oxygen data is obtained or the obtained blood oxygen data is invalid, continue to obtain blood oxygen data. If valid blood oxygen data is obtained, execute step 902.

[0296] In step 901, if blood oxygen data cannot be obtained during the current adjustment interval, or the obtained blood oxygen data is invalid, that is, the blood oxygen data is not within the range of 0 to 100% and is an invalid value, it means that the blood oxygen data is unmeasurable, and timing is performed. If blood oxygen data is obtained during the current adjustment interval and the obtained blood oxygen data is within the range of 0 to 100% and is a valid value, it means that the blood oxygen data is measurable.

[0297] Step 902: Obtain associated data in the blood oxygen data that affects the blood oxygen credibility, and determine whether the associated data meets the blood oxygen credibility requirements; if so, execute step 905; if not, execute step 903.

[0298] In step 902, if the condition is met, the blood oxygen data is credible; if not, the blood oxygen data is not credible.

[0299] In step 902 , the associated data includes at least pulse rate and / or perfusion index and / or blood oxygen signal quality.

[0300] The blood oxygen signal quality in the associated data is a comprehensive judgment result of the blood oxygen signal intensity, time domain waveform, and frequency domain waveform. When the blood oxygen signal quality is low, it means that the blood oxygen signal intensity is low or the waveform disturbance is strong.

[0301] In one embodiment, if the associated data includes pulse rate, then:

[0302] Determine whether the pulse rate change rate is higher than the pulse rate change rate threshold; if so, the pulse rate does not meet the blood oxygen credibility requirement; if not, the pulse rate meets the blood oxygen credibility requirement, and the blood oxygen data is determined to be credible data.

[0303] Alternatively, determine whether the pulse rate is lower than the pulse rate threshold; if so, the pulse rate does not meet the blood oxygen credibility requirement; if not, the pulse rate meets the blood oxygen credibility requirement, and the blood oxygen data is determined to be credible data.

[0304] It should be noted that if it is necessary to determine whether the pulse rate is higher than the pulse rate change rate threshold and whether the pulse rate is lower than the pulse rate threshold, if both are negative, the pulse rate meets the blood oxygen credibility requirement and the blood oxygen data is determined to be credible data.

[0305] In one embodiment, if the associated data includes a perfusion index, then:

[0306] It is determined whether the perfusion index is lower than the perfusion index threshold; if so, the perfusion index does not meet the blood oxygen credibility requirement; otherwise, the perfusion index meets the blood oxygen credibility requirement.

[0307] In one embodiment, if the associated data includes blood oxygen signal quality, then:

[0308] Determine whether the blood oxygen signal quality is lower than the blood oxygen signal quality threshold; if so, the blood oxygen signal quality does not meet the blood oxygen credibility requirement; otherwise, the blood oxygen signal quality meets the blood oxygen credibility requirement.

[0309] In one embodiment, if the associated data includes pulse rate and perfusion index, then:

[0310] Determine whether the pulse rate change rate is higher than the pulse rate change rate threshold; if so, the pulse rate does not meet the blood oxygen credibility requirement; otherwise, the pulse rate meets the blood oxygen credibility requirement.

[0311] And / or, determining whether the pulse rate is lower than a pulse rate threshold; if so, the pulse rate does not meet the blood oxygen credibility requirement; if not, the pulse rate meets the blood oxygen credibility requirement.

[0312] and, determining whether the perfusion index is lower than the perfusion index threshold; if so, the perfusion index does not meet the blood oxygen credibility requirement; otherwise, the perfusion index meets the blood oxygen credibility requirement.

[0313] It should be noted that when the above judgment results for the pulse rate and perfusion index are both negative, that is, the pulse rate meets the blood oxygen credibility requirement, the perfusion index meets the blood oxygen credibility requirement, and the blood oxygen data is determined to be credible data.

[0314] Similarly, if the associated data includes any combination of pulse rate, perfusion index and blood oxygen signal quality, for example: pulse rate and blood oxygen signal quality; or, perfusion index and blood oxygen signal quality; or, pulse rate, perfusion index and blood oxygen signal quality, when the judgment on any data in the combination is no, the blood oxygen data is determined to be credible data; if the judgment on any data in the combination is yes, the blood oxygen data is determined to be uncredible data.

[0315] Step 903: Determine whether the result of unreliable blood oxygen data is continuous and the duration of continuous appearance exceeds the fourth time length. If so, execute step 904; if not, continue to obtain blood oxygen data and execute step 902.

[0316] After determining that the blood oxygen data is unreliable at step 902, step 903 is performed because the unreliable blood oxygen data may cause the automatic adjustment of the inhaled oxygen concentration to remain unadjusted for a long time, which may cause more serious problems. Therefore, an alarm prompt and manual intervention are required.

[0317] It should be noted that, for the result that the blood oxygen data is unreliable as determined in step 903, when the associated data leading to the unreliable result are different, that is, any one or a combination of pulse rate, perfusion index and blood oxygen signal quality, the fourth duration used to decide whether to execute the operation of prompting the user of the current adjustment status in step 903 may be different depending on the content contained in the associated data.

[0318] Step 904: Execute an alarm operation.

[0319] In the embodiment of the present application, the alarm operation is mainly to remind the user that the automatic adjustment of the current inhaled oxygen concentration is in a paused state.

[0320] It should be noted that the notification method for the user of the current inhaled oxygen concentration adjustment status should at least include a text string and / or graphic and / or audio prompt. The prompt content should include the current adjustment status and / or the reasons leading to the current adjustment status. When multiple conditions are met simultaneously, all reasons can be prompted, or the user can choose to prompt based on the built-in condition priority, with the highest priority reason being prompted.

[0321] In one embodiment, the user may be prompted that the automatic adjustment of the current inhaled oxygen concentration is in a paused state through an alarm string, an alarm sound, or a detailed string displayed on the system operation interface.

[0322] In one embodiment, the user may be prompted with the reason for the pause state based on the judgment result of the associated data used in the above judgment of whether the blood oxygen data is credible.

[0323] For example, if the perfusion index is too low for a long time, that is, the perfusion index is below the perfusion index threshold for a long time, the user will be prompted with "Current adjustment is suspended. The reason for the suspension is that the perfusion index is too low for a long time." In specific implementations, the prompt words displayed on the specific system operation interface can be configured by the technician.

[0324] If it is caused by the perfusion index and blood oxygen signal quality being too low for a long time, it may be prompted at the same time that "the current adjustment is suspended. The reason for the suspension is that the perfusion index and blood oxygen signal quality are too low for a long time."

[0325] If the prompt priority of the blood oxygen signal quality is higher than the perfusion index, the prompt may be "Current adjustment is suspended. The reason for the suspension is that the perfusion index has been too low for a long time."

[0326] In an embodiment of the present application, after an alarm operation is performed to prompt the user of the current automatic adjustment status of the inhaled oxygen concentration and the reason, the user can be authorized or started to manually set the inhaled oxygen concentration. That is, in a special state where the blood oxygen data is unreliable, the function of automatically adjusting the inhaled oxygen concentration will inform the user that the current automatic adjustment is suspended due to certain factors. At this time, the user can manually set a new inhaled oxygen concentration until the blood oxygen data becomes reliable again.

[0327] It should be noted that when the function of automatically adjusting the inhaled oxygen concentration is restored, the system can use the new inhaled oxygen concentration manually set by the user as the control value and continue subsequent adjustments based on this control value; it can also use the inhaled oxygen concentration before restoration as the control value and continue subsequent adjustments based on this control value.

[0328] It should be further noted that when the function of automatically adjusting the inhaled oxygen concentration is enabled, any of the control values of the inhaled oxygen concentration disclosed above in the embodiments of the present application will be displayed on the user interface of the system, prompting the user of the control value result of the currently automatically adjusted inhaled oxygen concentration.

[0329] At this time, the user can also manually set the inspired oxygen concentration. If the inspired oxygen concentration is manually set by the user during the automatic adjustment of the inspired oxygen concentration, the automatic adjustment function will continue to adjust the inspired oxygen concentration at the newly set inspired oxygen concentration.

[0330] Based on the above description, there should be at least one entrance on the user operation interface of the system for the user to manually set the oxygen concentration. When the automatic adjustment function of the inhaled oxygen concentration is not enabled, the inhaled oxygen concentration can be changed by manually setting the inhaled oxygen concentration. After the automatic adjustment function of the inhaled oxygen concentration is enabled, the original entrance for manually setting the oxygen concentration will display the result of the current inhaled oxygen concentration automatic adjustment function.

[0331] It should be noted that the user operation interface and display interface of the system can be set separately or combined.

[0332] In one embodiment, the area where the user manually sets the inhaled oxygen concentration can be separated from the display area for the automatically adjusted inhaled oxygen concentration result. The user only needs to set the inhaled oxygen concentration through one entrance and read the automatically adjusted inhaled oxygen concentration result through another entrance.

[0333] On the basis of the above settings, a backup oxygen concentration setting area can be added to allow the user to manually set the inhaled oxygen concentration during a period when the blood oxygen data is unreliable for a long time.

[0334] Step 905: Determine the blood oxygen partition corresponding to each piece of blood oxygen data.

[0335] The execution principle of step 905 and the blood oxygen zoning involved are the same as the execution principle of step 101 and the blood oxygen zoning involved. For details, please refer to the above description of step 101, which will not be repeated here.

[0336] Step 906: Determine whether the severity of each blood oxygen data satisfies the condition for triggering the adjustment of the inhaled oxygen concentration in advance. If so, execute step 907; if not, execute step 908.

[0337] Step 907: Execute the operation of adjusting the inhaled oxygen concentration in advance if the condition for triggering the adjustment of the inhaled oxygen concentration in advance is met.

[0338] Step 908: After the current adjustment interval is over, the operation of adjusting the inhaled oxygen concentration is performed normally.

[0339] The execution principle of steps 906 to 908 is the same as that of steps 102 to 104 above. For details, please refer to the above description of steps 102 to 104, which will not be repeated here.

[0340] In the method for adjusting the inspired oxygen concentration disclosed in the embodiments of the present application, the credibility of blood oxygen data is assessed. Changes in the severity of the credible blood oxygen data are used to determine whether to trigger early adjustment of the inspired oxygen concentration. If early triggering of inspired oxygen concentration adjustment is determined, the inspired oxygen concentration is adjusted promptly based on an adjustment strategy corresponding to the blood oxygen change trend within the current adjustment interval. This allows for more accurate and rapid response to rapid changes in a patient's blood oxygen level and adjustment of the inspired oxygen concentration.

[0341] It should be noted that based on the above Figure 1 and Figure 9 The method for adjusting the inhaled oxygen concentration disclosed in the embodiment of the present application shown in the figure can also simultaneously obtain the system operating status in parallel during the execution of the above method to determine whether the system operating status is in a normal operating state.

[0342] If the system operation status is in normal operation, it means that nothing has occurred that may affect the normal operation of the system. If it is satisfied, the system operation status is normal. If it is not satisfied, the system operation status is abnormal.

[0343] If the system operation status is in an abnormal operation state, the abnormal operation state includes respiratory support equipment failure, abnormal connection status between the equipment and the patient, etc., and should at least include abnormal pressure, flow rate control or monitoring of the equipment, abnormal control process of the equipment mixing air and oxygen to produce a new oxygen concentration gas, abnormal oxygen concentration monitoring function of the equipment, excessive gas leakage or blockage during the gas supply process, and disconnection of the gas supply pipeline between the equipment and the patient.

[0344] It should be noted that when a system anomaly occurs, it will affect the system's performance and the control of the inhaled oxygen concentration, which may further affect the device's therapeutic effect. In this case, automatically adjusting the oxygen concentration is of little significance, and the system operation problem should be solved first. Therefore, in the process of concurrently obtaining the system operation status and determining whether the system operation status is in a normal state, if the system operation status is found to be abnormal, an alarm will be issued, allowing the user to prioritize the system operation problem.

[0345] Based on the above Figure 1 and Figure 9 The embodiment of the present application shows a method for adjusting the inhaled oxygen concentration, in which the operation of adjusting the inhaled oxygen concentration requires determining the blood oxygen change trend within the current adjustment interval, and then determining different adjustment strategies based on different blood oxygen change trends, and adjusting the inhaled oxygen concentration according to the adjustment strategies.

[0346] The specific process of determining the blood oxygen change trend based on the specified blood oxygen zone is as follows:

[0347] First, a first blood oxygen type indicated by a designated blood oxygen zone and a second blood oxygen type indicated by a reference blood oxygen zone are determined.

[0348] The blood oxygen type includes at least severe hypoxia, severe hyperoxia, moderate hypoxia, moderate hyperoxia, mild hypoxia, mild hyperoxia and normal state. The blood oxygen type can be determined by the blood oxygen saturation range of the blood oxygen zone.

[0349] Then, the current blood oxygen change trend can be obtained according to the first blood oxygen type indicated by the designated blood oxygen partition and the second blood oxygen type indicated by the reference blood oxygen partition.

[0350] If the first blood oxygen type is severe hypoxia or severe hyperoxia, it is determined that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend.

[0351] If the first blood oxygen type tends to be more serious than the blood oxygen type indicated by the second blood oxygen type, it is determined that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend.

[0352] If the first blood oxygen type and the second blood oxygen type are consistent and neither is severe hypoxia or severe hyperoxia, it is determined that the blood oxygen change trend within the current adjustment interval is a blood oxygen stable trend.

[0353] If the first blood oxygen type tends to improve relative to the blood oxygen type indicated by the second blood oxygen type, it is determined that the blood oxygen change trend within the current adjustment interval is a blood oxygen improvement trend.

[0354] In the embodiment of the present application, the judgment of the first blood oxygen type can be performed from severe to mild, or from mild to severe. The following is just an example. Figure 10 FIG. 1 is a flow chart of analyzing a blood oxygen change trend according to an embodiment of the present application, including the following steps:

[0355] Step 1001: Obtain a first blood oxygen type corresponding to a designated blood oxygen partition and a second blood oxygen type corresponding to a reference blood oxygen partition.

[0356] Step 1002: Determine whether the first blood oxygen type is severe hypoxia. If so, determine whether the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend; if not, execute step 1003.

[0357] Step 1003: Determine whether the first blood oxygen type is severe hyperoxia. If so, determine that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend; if not, execute step 1004.

[0358] That is, if the first blood oxygen type indicated by the control blood oxygen zone is severe hypoxia or severe hyperoxia: it is determined that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend.

[0359] Step 1004: Determine whether the first blood oxygen type is moderate hypoxia. If so, perform blood oxygen trend analysis under moderate hypoxia; if not, execute step 1005.

[0360] In one embodiment, the blood oxygen trend analysis under moderate hypoxia is as follows Figure 11 As shown, it mainly includes the following steps:

[0361] Step 1101: Determine whether the second blood oxygen type is severe hypoxia. If so, determine whether the blood oxygen change trend within the current adjustment interval is a blood oxygen improvement trend; if not, execute step 1102.

[0362] Step 1102: Determine whether the second blood oxygen type is moderate hypoxia. If so, determine that the blood oxygen change trend within the current adjustment interval is a blood oxygen stabilization trend; if not, determine that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend.

[0363] It should be noted that, if step 1102 is performed on the basis of first executing step 1101 to determine that the second blood oxygen type is not severe hypoxia, and the second blood oxygen type is determined to be not moderate hypoxia, then it can be concluded that the second blood oxygen type may be mild hypoxia or a normal state. Compared with the moderate hypoxia indicated by the current first blood oxygen type, the blood oxygen state is in a deteriorating trend.

[0364] Step 1005: Determine whether the first blood oxygen type is moderate hyperoxia. If so, perform blood oxygen trend analysis under moderate hyperoxia; if not, execute step 1006.

[0365] In one embodiment, the blood oxygen trend analysis under moderate hyperoxia is as follows: Figure 12 As shown, it mainly includes the following steps:

[0366] Step 1201: Determine whether the second blood oxygen type is severe hyperoxia. If so, determine that the blood oxygen change trend within the current adjustment interval is a blood oxygen improvement trend; if not, execute step 1202.

[0367] Step 1202: Determine whether the second blood oxygen type is moderate hyperoxia. If so, determine that the blood oxygen change trend within the current adjustment interval is a blood oxygen stabilization trend. If not, determine that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend.

[0368] It should be noted that, if step 1202 is performed on the basis of first executing step 1201 to determine that the second blood oxygen type is not severe hyperoxygenation, and the second blood oxygen type is determined to be not moderate hyperoxygenation, then it can be concluded that the second blood oxygen type may be mild hyperoxygenation or a normal state. Compared with the moderate hyperoxygenation indicated by the current first blood oxygen type, the blood oxygen state is in a deteriorating trend.

[0369] Step 1006: Determine whether the first blood oxygen type is mild hypoxia. If so, perform blood oxygen trend analysis under mild hypoxia; if not, execute step 1007.

[0370] In one embodiment, blood oxygen trend analysis under mild hypoxia is as follows Figure 13 As shown, it mainly includes the following steps:

[0371] Step 1301: Determine whether the second blood oxygen type is severe hypoxia or moderate hypoxia. If so, determine whether the blood oxygen change trend within the current adjustment interval is a blood oxygen improvement trend; if not, execute step 1302.

[0372] Step 1302: Determine whether the second blood oxygen type is mild hypoxia. If so, determine that the blood oxygen change trend within the current adjustment interval is a blood oxygen stabilization trend; if not, determine that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend.

[0373] It should be noted that, if step 1302 is executed on the basis of first executing step 1301 to determine that the second blood oxygen type is not severe hypoxia or moderate hypoxia, and the second blood oxygen type is not mild hypoxia, it can be concluded that the second blood oxygen type may be in a normal state, and the blood oxygen state is in a deteriorating trend relative to the mild hypoxia indicated by the current first blood oxygen type.

[0374] Step 1007: Determine whether the first blood oxygen saturation is mild hyperoxia. If so, perform blood oxygen trend analysis under mild hyperoxia; if not, determine the control blood oxygen zone as the treatment target zone.

[0375] In one embodiment, blood oxygen trend analysis under mild hyperoxia is as follows Figure 14 As shown, it mainly includes the following steps:

[0376] Step 1401: Determine whether the second blood oxygen type is severe hyperoxia or moderate hyperoxia. If so, determine that the blood oxygen change trend within the current adjustment interval is a blood oxygen improvement trend; if not, execute step 1402.

[0377] Step 1402: Determine whether the second blood oxygen type is mild hyperoxia. If so, determine that the blood oxygen change trend within the current adjustment interval is a blood oxygen stabilization trend; if not, determine that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend.

[0378] It should be noted that, if step 1402 is executed on the basis of first executing step 1401 to determine that the second blood oxygen type is not severe hyperoxia or moderate hyperoxia, and the second blood oxygen type is obtained to be not mild hypoxia, it can be concluded that the second blood oxygen type may be in a normal state, and the blood oxygen state is in a deteriorating trend relative to the mild hypoxia indicated by the current first blood oxygen type.

[0379] Based on the execution of the above Figure 10 ,as well as Figures 11 to 14 The blood oxygen trend analysis shows the blood oxygen change trend. Different adjustment strategies are determined according to different blood oxygen change trends. The following multiple adjustment strategies can be obtained to adjust the inhaled oxygen concentration.

[0380] In one embodiment, if the blood oxygen change trend is a deteriorating trend, a corresponding adjustment strategy B or C is determined based on the blood oxygen change trend.

[0381] Among them, the situation where adjustment strategy B needs to be executed is: the current patient's blood oxygen change characteristics are that the blood oxygen data continues to change in the direction of deviating from the treatment target partition, but the patient's blood oxygen level is not too dangerous.

[0382] Adjustment strategy B is: according to the offset of the blood oxygen data in the specified blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone, the blood oxygen change rate during the last adjustment of the inhaled oxygen concentration, and the preset maximum single oxygen concentration adjustment amount, a first oxygen concentration target adjustment amount is obtained; when the first oxygen concentration target adjustment amount is less than or equal to the preset maximum single oxygen concentration adjustment amount, the inhaled oxygen concentration is adjusted with the first oxygen concentration target adjustment amount; when the first oxygen concentration target adjustment amount is greater than the preset maximum single oxygen concentration adjustment amount, the inhaled oxygen concentration is adjusted with the preset maximum single oxygen concentration adjustment amount, and the difference between the first oxygen concentration target adjustment amount and the preset maximum single oxygen concentration adjustment amount is used as the residual adjustment amount and added to the cumulative adjustment amount of the specified blood oxygen zone.

[0383] The preset maximum single oxygen concentration adjustment amount can be built into the machine by medical personnel according to the patient type. The preset maximum single oxygen concentration adjustment amount can be set to different adjustment amounts based on different patient types.

[0384] For example, for newborns, the preset maximum single oxygen concentration adjustment amount is optionally set to 3%. For children, the preset maximum single oxygen concentration adjustment amount is optionally set to 4%. For adults, the preset maximum single oxygen concentration adjustment amount is optionally set to 6%.

[0385] The accumulated adjustment amount added to the designated blood oxygen concentration zone is used to calculate the target adjustment amount for the next adjustment interval. That is, if there is an accumulated adjustment amount in the designated blood oxygen concentration zone where the inhaled oxygen concentration needs to be adjusted in the next adjustment interval, then if the adjustment is still performed in the designated blood oxygen concentration zone in the next adjustment interval, the accumulated adjustment amount in the designated blood oxygen concentration zone is added to the target adjustment amount, and the accumulated target adjustment amount is compared with the preset maximum single oxygen concentration adjustment amount.

[0386] The situation where adjustment strategy C needs to be executed is: the current patient's blood oxygen change characteristics are that the blood oxygen zone where the blood oxygen data is located is relatively far away from the treatment target zone, indicating that the patient's current blood oxygen situation is not optimistic.

[0387] Adjustment strategy C is: adjusting the inhaled oxygen concentration according to the preset maximum single oxygen concentration adjustment amount, and changing the duration of the next adjustment interval to the fifth duration. The fifth duration is shorter than the duration of the regular adjustment interval.

[0388] Regulation strategy C uses a shorter adjustment interval to adjust the inhaled oxygen concentration according to a fixed oxygen concentration adjustment amount, which can achieve faster oxygen concentration adjustment when the patient's hypoxia or hyperoxia is more serious.

[0389] Specifically, the process of adjusting the inhaled oxygen concentration according to adjustment strategy B or C is as follows: Figure 15 Shown, including:

[0390] Step 1501: Analyze whether the deterioration trend of blood oxygen deterioration is severe hypoxia or severe hyperoxia. If so, execute step 1502; if not, execute steps 1503 and 1504.

[0391] Step 1502: Change the duration of the current adjustment interval to the fifth duration, and adjust the inhaled oxygen concentration according to the preset maximum single oxygen concentration adjustment amount.

[0392] Step 1502 corresponds to adjustment strategy C. Adjustment strategy C is executed, and adjustment is performed based on the preset maximum single oxygen concentration adjustment amount until the target adjustment amount is achieved, or until a new, smaller target adjustment amount is generated.

[0393] Step 1503: Calculate the difference between the blood oxygen saturation in the designated blood oxygen zone and the upper limit of the blood oxygen saturation in the treatment target zone to obtain a first difference.

[0394] In step 1503, the blood oxygen saturation in the specified blood oxygen zone is the blood oxygen data in the specified blood oxygen zone, and the blood oxygen data can be represented by the blood oxygen saturation.

[0395] It should be noted that the designated blood oxygen partition refers to the recommended blood oxygen partition containing the most severe blood oxygen data in the current interval, and the most severe blood oxygen data is obtained in the current interval.

[0396] Optionally, if the upper limit of the treatment target partition is represented by blood oxygen data, the difference between the blood oxygen data in the specified blood oxygen partition and the upper limit blood oxygen data of the treatment target partition can also be calculated to obtain the first difference.

[0397] Step 1504: Calculate the difference between the first blood oxygen saturation and the lower limit blood oxygen saturation of the treatment target zone to obtain a second difference.

[0398] Step 1505: Calculate the first oxygen concentration target adjustment amount based on the blood oxygen change rate, the first difference, and the second difference during the previous adjustment of the inhaled oxygen concentration.

[0399] Step 1506: Compare the first oxygen concentration target adjustment amount with the preset maximum single oxygen concentration adjustment amount. If the first oxygen concentration target adjustment amount is greater than the preset maximum single oxygen concentration adjustment amount, execute step 1507; if the first oxygen concentration target adjustment amount is not greater than the preset maximum single oxygen concentration adjustment amount, execute step 1509.

[0400] Step 1507: Adjust the inhaled oxygen concentration according to the preset maximum single oxygen concentration adjustment amount, and obtain the remaining amount obtained by subtracting the preset maximum single oxygen concentration adjustment amount from the first oxygen concentration target adjustment amount.

[0401] Step 1508: Add the remaining amount to the cumulative adjustment amount of the specified blood oxygen zone.

[0402] In step 1508, the remaining amount is added to the cumulative adjustment amount of the specified blood oxygen partition, so that the adjustment amount of the specified blood oxygen partition will be used when calculating the target adjustment amount of the specified blood oxygen partition in the next adjustment interval.

[0403] For example, assuming that the first oxygen concentration target adjustment amount is 8% based on the blood oxygen change rate, the first difference, and the second difference during the previous adjustment of the inhaled oxygen concentration, and the preset maximum single oxygen concentration adjustment amount is 8%, then the current interval uses 5%, and the remaining amount is 3%. This remaining amount of 3% is added to the cumulative adjustment amount of the specified blood oxygen partition. Continue to the next adjustment interval. When calculating the first oxygen concentration target adjustment amount again, it is necessary to accumulate a 3% adjustment amount. If the first oxygen concentration target adjustment amount obtained after accumulation is still greater than the preset maximum single oxygen concentration adjustment amount, continue to adjust with the preset maximum single oxygen concentration adjustment amount, and add the remaining amount this time to the cumulative adjustment amount of the specified blood oxygen partition. And so on, until the adjustment is completed.

[0404] Step 1509: Adjust the inhaled oxygen concentration according to the first oxygen concentration target adjustment amount.

[0405] Steps 1503 to 1509 correspond to adjustment strategy B, which adjusts the inhaled oxygen concentration based on the first oxygen concentration target adjustment amount until the target adjustment amount is achieved, or until a new, smaller target adjustment amount is generated.

[0406] It should be noted that when the adjustment strategy B is executed to calculate the target adjustment amount, the coefficients used to calculate the target adjustment amount are different under different current interval blood oxygen overall partition results.

[0407] For example, the coefficient when the overall blood oxygen partition of the current interval is "moderate hypoxia" will be larger than the coefficient when the overall partition is "mild hypoxia", so as to obtain a larger adjustment amount, thereby ensuring that the adjustment strength of the inhaled oxygen concentration is different under different degrees of hypoxia or hyperoxia.

[0408] In one embodiment, if the blood oxygen change trend is a blood oxygen stabilization trend or a blood oxygen improvement trend, a corresponding adjustment strategy D is determined based on the blood oxygen change trend.

[0409] Among them, the situation where adjustment strategy D needs to be executed is: the patient's blood oxygen data continues to be stable within a blood oxygen zone indicating the current blood oxygen change trend, the blood oxygen data remains unchanged or changes in the direction of the treatment target zone, but is still not within the treatment target zone.

[0410] Adjustment strategy D is as follows: obtaining an adjustment amount for adjusting the inhaled oxygen concentration during the last adjustment interval in which the blood oxygen change trend was a stable or improving trend, then adding a preset adjustment amount to the adjustment amount to obtain a second oxygen concentration target adjustment amount, and adjusting the inhaled oxygen concentration based on the second oxygen concentration target adjustment amount. The second oxygen concentration target adjustment amount is no greater than the preset minimum oxygen concentration adjustment amount.

[0411] In adjustment strategy D, every time an adjustment interval occurs in which the blood oxygen change trend is a stable trend or an improving trend, a very small preset adjustment amount is added to the adjustment amount of the previous adjustment interval with the same situation, until the accumulated result exceeds the preset minimum oxygen concentration adjustment amount.

[0412] In the embodiment of the present application, the preset minimum oxygen concentration adjustment amount represents the minimum oxygen concentration setting value that the machine can distinguish when adjusting the inhaled oxygen concentration. Optionally, the minimum oxygen concentration setting value is usually 1%.

[0413] Optionally, the preset cumulative adjustment amount in adjustment strategy D may also be adjusted to different amounts based on the current overall blood oxygen zone. For example, for a patient whose blood oxygen level is in a "mild hypoxia" state for a long time, a 0.5% adjustment amount will be accumulated in each adjustment cycle; for a patient whose blood oxygen level is in a "moderate hypoxia" state for a long time, a 0.67% adjustment amount will be accumulated in each adjustment cycle.

[0414] It should be noted that if the inhaled oxygen concentration is adjusted when the adjustment strategy D is executed, the designated blood oxygen zone to be adjusted at this time also has the remaining amount of the previous adjustment cycle described in the adjustment strategy B that has not been completed. When the adjustment strategy D is executed, the accumulated adjustment amount will be added to the remaining adjustment amount to calculate the inhaled oxygen concentration.

[0415] In one embodiment, if the blood oxygen change trend is a stable blood oxygen trend, a corresponding adjustment strategy E is determined based on the blood oxygen change trend.

[0416] Among them, the situation where adjustment strategy E needs to be executed is: the patient's blood oxygen data continues to be stable within a blood oxygen zone indicating the current blood oxygen change trend, but the blood oxygen data changes in the direction of deviating from the treatment target zone and is still not within the treatment target zone.

[0417] Unlike the above-mentioned situation where adjustment strategy D needs to be executed, when adjustment strategy E is executed, the patient's blood oxygen data continues to change in the direction of deviating from the treatment target partition, but because the blood oxygen data still does not deviate from the current designated blood oxygen partition, it can be determined that the current offset is small, but the offset may indicate that the patient's blood oxygen status may further deteriorate, so adjustment strategy E is executed.

[0418] Adjustment strategy E is: based on the offset of the upper and lower blood oxygen data boundaries of the treatment target partition of the blood oxygen data in the specified blood oxygen partition and the cumulative adjustment amount of the specified blood oxygen partition, a third oxygen concentration target adjustment amount is obtained, and the inhaled oxygen concentration is adjusted based on the third oxygen concentration target adjustment amount.

[0419] It should be noted that the cumulative adjustment amount of the specified blood oxygen partition may be the accumulated adjustment amount of the specified blood oxygen partition over multiple continuous adjustment intervals.

[0420] In one embodiment, if the blood oxygen change trend is a stable blood oxygen trend, a corresponding adjustment strategy F or G is determined based on the blood oxygen change trend.

[0421] Among them, the situation where adjustment strategy F or G needs to be executed is: the patient stays in the treatment target zone for a long time and the patient's blood oxygen data is normal.

[0422] At this time, for different groups of people or special scenarios, if the patient is in the treatment target zone for a long time, it is also necessary to consider whether the use of oxygen can be reduced based on the changes in the patient's blood oxygen data.

[0423] For example, for neonatal patients, oxygen poisoning caused by excessively high oxygen concentrations should be avoided.

[0424] For example, in a transport scenario, oxygen usage can be reduced while ensuring that the patient's blood oxygen data is within the target range.

[0425] For example, by adjusting strategy F or G, the patient's dependence on oxygen concentration can be reduced, and ventilator removal can be assisted.

[0426] Specifically, the process of adjusting the inhaled oxygen concentration according to adjustment strategy F or G includes:

[0427] First, determine the area where the blood oxygen data is located in the treatment target partition.

[0428] In one embodiment, the treatment target zone includes at least a downstream region, a midstream region, and an upstream region;

[0429] If the second blood oxygen saturation is in the downstream area, the current adjustment of the inhaled oxygen concentration is maintained.

[0430] If the second blood oxygen saturation is in the middle range, the adjustment strategy F is executed, the first timer is started, and when the first timer ends, the inhaled oxygen concentration is reduced according to the preset minimum oxygen concentration adjustment amount.

[0431] If the second blood oxygen saturation is in the upstream region, the adjustment strategy G is executed, the second timing is started, and when the second timing ends, the inhaled oxygen concentration is reduced according to the preset minimum oxygen concentration adjustment amount.

[0432] The second timing is greater than the first timing. The first timing and the second timing can be countdown or countdown.

[0433] It should be noted that when the patient's blood oxygen data appears alternately in the upstream area and the midstream area, the timing is used alternately, and the timing is paused when the patient's blood oxygen data appears in the downstream area. Thus, for patients whose blood oxygen data is maintained in the midstream area of the treatment target partition for a long time, oxygen reduction will be triggered after a longer period of observation. For patients whose blood oxygen data is maintained in the upstream area of the treatment target partition for a long time, the observation time for triggering oxygen reduction will be shortened, thereby preventing the patient's blood oxygen data from further deviating from the upper limit of the treatment target partition. In an embodiment of the present invention, the first timing and the second timing can be set by medical staff based on experience, or can be set differently by medical staff according to the type of patient. Optionally, the duration of the first timing can be set to 90 seconds.

[0434] In the process of adjusting the inhaled oxygen concentration based on the various adjustment strategies disclosed in the above-mentioned embodiments of the present invention, in general, the automatically adjusted inhaled oxygen concentration is adjusted within the inhaled oxygen concentration range set by the user, that is, the adjustment result will not exceed the range set by the user. However, in some cases, the inhaled oxygen concentration upper limit set by the user is too low. In this case, after the automatic adjustment function adjusts to the upper limit, the patient's blood oxygen level is still lower than the target. In this case, the oxygen concentration will continue to be adjusted upward beyond the oxygen concentration upper limit set by the user.

[0435] In one embodiment, the user can set the oxygen concentration range during the automatic adjustment process. This ensures that the result of the automatic adjustment is within the set range, improving process safety. Optionally, the inhaled oxygen concentration range includes two values: a lower limit and an upper limit.

[0436] When the user sets a clear inhaled oxygen concentration range, it is allowed that the automatically adjusted inhaled oxygen concentration result has been adjusted to the boundary value of the oxygen concentration range, but the patient's blood oxygen is still outside the treatment target range set by the doctor.

[0437] It should be further clarified that if the result of automatically adjusting the inspired oxygen concentration reaches the upper limit of the user-set oxygen concentration range, but the patient's blood oxygen readings remain below the treatment target zone for a period exceeding the fifth duration, the user will be prompted with the aforementioned status, including but not limited to a text string, a graphical representation, or a sound on the user interface. Based on this status, if the patient's blood oxygen readings continue to fall below a threshold for a period exceeding the sixth duration, the inspired oxygen concentration may be temporarily adjusted without being constrained by the user-set upper limit of the inspired oxygen concentration range.

[0438] Similarly, when the result of automatically adjusting the inhaled oxygen concentration has reached the lower limit of the oxygen concentration range set by the user, and the patient's blood oxygen level is still higher than the treatment target zone and continues to exceed a time threshold, the user is prompted of this status. The prompt method includes but is not limited to the appearance of a character string, a graphic diagram, and a sound on the user interface.

[0439] In the method for adjusting the inspired oxygen concentration disclosed in the embodiments of the present application, the severity of the patient's blood oxygen status is identified by changes in the severity of the blood oxygen status of the blood oxygen zone where the blood oxygen data is located. Therefore, when subsequently adjusting the inspired oxygen concentration, different adjustment strategies can be determined based on the severity of the blood oxygen status corresponding to the blood oxygen zone, and the inspired oxygen concentration should be adjusted promptly according to the corresponding adjustment strategy. This can achieve the purpose of more accurately and quickly responding to rapid changes in the patient's blood oxygen level and adjusting the inspired oxygen concentration.

[0440] Based on the method for adjusting the inhaled oxygen concentration provided in the above-mentioned embodiment of the present application, the embodiment of the present application also discloses a respiratory support device. In one embodiment, the respiratory support device can be a ventilator.

[0441] like Figure 16 FIG. 1 is a schematic diagram of a respiratory support device disclosed in an embodiment of the present application. The respiratory support device 1600 includes a ventilation device 1601 and a processor 1602 .

[0442] Ventilation device 1601 is used to provide oxygen-containing inhaled gas to a patient via a breathing circuit and respiratory accessories. The breathing circuit consists of an expiratory branch and an inspiratory branch. The respiratory accessories include at least a pneumatic system and a patient interface, which is typically a mask. Specifically, one end of the pneumatic system of ventilation device 1601 is signal-connected to processor 1602, and the other end is connected to the patient interface via the expiratory branch and the inspiratory branch.

[0443] The processor 1602 is signal-connected to the ventilation device 1601 to control the flow rate of inhaled gas provided by the ventilation device 1601 to the patient.

[0444] The processor 1602 itself is configured with a sensor, or is interconnected with an external detection device.

[0445] In one embodiment, the external detection device may be a pulse oximeter, a monitor, or the like.

[0446] The processor 1602 obtains blood oxygen data based on its own configured sensors or through an interconnected external detection device.

[0447] The processor 1602 is configured to determine a blood oxygen partition corresponding to each piece of blood oxygen data, where the blood oxygen partition is pre-divided based on blood oxygen saturation.

[0448] Processor 1602 is configured to obtain, in real time, each piece of blood oxygen data for the current adjustment interval and determine the recommended blood oxygen zone to which each piece of blood oxygen data belongs. Processor 1602 determines whether the severity of each piece of blood oxygen data satisfies a condition for triggering early adjustment of the inspired oxygen concentration. The severity refers to the degree to which the blood oxygen data deviates from the treatment target zone. The condition for triggering early adjustment of the inspired oxygen concentration includes increasing severity. The recommended blood oxygen zone and the treatment target zone each correspond to a pre-defined blood oxygen data range.

[0449] The operation of adjusting the intake oxygen concentration is performed when the condition for triggering the adjustment of the intake oxygen concentration in advance is met; otherwise, the operation of adjusting the intake oxygen concentration is performed normally.

[0450] In one embodiment, the processor 1602 may be a host computer, a controller, or a control device in a ventilator.

[0451] Optionally, the processor 1602 that performs the operation of adjusting the inhaled oxygen concentration is specifically configured to:

[0452] Obtaining a designated blood oxygen partition for the current adjustment interval, where the designated blood oxygen partition refers to a recommended blood oxygen partition containing the most severe blood oxygen data among the blood oxygen partitions determined within the current adjustment interval;

[0453] A blood oxygen change trend is determined based on the designated blood oxygen zone, and the inhaled oxygen concentration is adjusted according to a regulation strategy corresponding to the blood oxygen change trend.

[0454] Optionally, the processor 1602 for determining whether the severity of each blood oxygen data satisfies the condition for triggering the adjustment of the inhaled oxygen concentration in advance is specifically configured to:

[0455] A reference blood oxygen zone corresponding to the most severe blood oxygen state within a previous adjustment interval is determined. The duration of the previous adjustment interval and the current adjustment interval may not be the same.

[0456] Obtain a reference blood oxygen partition containing the most severe blood oxygen data within the previous adjustment interval. The duration of the previous adjustment interval and the current adjustment interval may not be the same.

[0457] The severity of the blood oxygen data obtained in the current adjustment interval is compared in real time with the severity of the blood oxygen data of the reference blood oxygen zone.

[0458] Before the timing of the current adjustment interval ends, the number of blood oxygen data obtained in the current adjustment interval whose severity is greater than the severity of the blood oxygen data of the reference blood oxygen zone exceeds a preset number, and the condition for early triggering the adjustment of the inhaled oxygen concentration is met; otherwise, the condition for early triggering the adjustment of the inhaled oxygen concentration is not met.

[0459] Optionally, the processor 1602 for determining whether the severity of each blood oxygen data satisfies the condition for triggering the adjustment of the inhaled oxygen concentration in advance is specifically configured to:

[0460] Starting from the start time of the current adjustment interval, at intervals of a first duration, it is determined whether the severity of the blood oxygen data corresponding to each acquired blood oxygen concentration data item continuously increases, where the first duration is less than the duration of the current adjustment interval. If a continuous increase occurs, a condition for triggering early adjustment of the inhaled oxygen concentration is met; otherwise, the condition for triggering early adjustment of the inhaled oxygen concentration is not met.

[0461] The processor 1602 is further configured to:

[0462] It is determined in real time whether the duration of each blood oxygen data in the recommended blood oxygen zone is less than or equal to the second duration for a third duration, and the third duration is greater than the second duration and less than or equal to the duration of the current adjustment interval.

[0463] If it has lasted for the third time, the adjustment of the inhaled oxygen concentration is triggered according to the adjustment strategy corresponding to the uncertain blood oxygen triggering mode. Otherwise, it is continued to determine whether the severity of each blood oxygen data meets the conditions for triggering the adjustment of the inhaled oxygen concentration in advance.

[0464] Optionally, the processor 1602 for triggering adjustment of the inhaled oxygen concentration according to the adjustment strategy corresponding to the uncertain blood oxygen triggering mode is specifically configured to:

[0465] The weights of each recommended blood oxygen partition are cumulatively calculated to obtain a total weight, wherein the recommended blood oxygen partitions corresponding to different blood oxygen data ranges have different weights, and the size of the weight is determined by the severity of the blood oxygen data.

[0466] The total weight is compared with a first weight threshold and a second weight threshold respectively, the first weight threshold is used to indicate an increase in oxygen concentration and a first inhaled oxygen concentration adjustment amount, the second weight threshold is used to indicate a decrease in oxygen concentration and a second inhaled oxygen concentration adjustment amount, and the first weight threshold is greater than the second weight threshold.

[0467] If the total weight is greater than or equal to the first weight threshold, it is determined to increase the first inhaled oxygen concentration adjustment amount.

[0468] If the total weight is less than or equal to the second weight threshold, it is determined to reduce the second inhaled oxygen concentration adjustment amount.

[0469] If the total weight is less than the first weight threshold and greater than the second weight threshold, an adjustment amount for maintaining the current inhaled oxygen concentration is determined.

[0470] The processor 1602 is further configured to:

[0471] After receiving the various blood oxygen data acquired by the acquisition device, the associated data affecting the blood oxygen credibility in the blood oxygen data is acquired; whether the associated data meets the blood oxygen credibility requirements is determined; if so, the blood oxygen partition corresponding to the blood oxygen data is determined; if not, the blood oxygen data is continued to be acquired.

[0472] If the associated data includes at least pulse rate and / or perfusion index and / or blood oxygen signal quality, the processor 1602 determines whether the associated data meets preset requirements, specifically for:

[0473] determining whether the pulse rate change rate is higher than a pulse rate change rate threshold;

[0474] If the pulse rate change rate is higher than the pulse rate change rate threshold, the pulse rate does not meet the blood oxygen credibility requirement; otherwise, the pulse rate meets the blood oxygen credibility requirement; and / or,

[0475] Determine whether the pulse rate is lower than the pulse rate threshold;

[0476] If the pulse rate is lower than the pulse rate threshold, the pulse rate does not meet the blood oxygen credibility requirement; otherwise, the pulse rate meets the blood oxygen credibility requirement; and / or,

[0477] Determine whether the perfusion index is lower than the perfusion index threshold;

[0478] If the perfusion index is lower than the perfusion index threshold, the perfusion index does not meet the blood oxygen credibility requirement; otherwise, the perfusion index meets the blood oxygen credibility requirement; and / or,

[0479] Determine whether the blood oxygen signal quality is lower than the blood oxygen signal quality threshold;

[0480] If the blood oxygen signal quality is lower than the blood oxygen signal quality threshold, the blood oxygen signal quality does not meet the blood oxygen credibility requirement; otherwise, the blood oxygen signal quality meets the blood oxygen credibility requirement.

[0481] The processor 1602 is further configured to:

[0482] Obtain the system operation status and determine whether the system operation status is in normal operation. If the system operation status is in normal operation, continue to maintain the operation status; if the system operation status is in abnormal operation, an alarm is issued to allow users to give priority to handling system operation problems.

[0483] The processor 1602 is further configured to:

[0484] If the associated data is continuously judged to not meet the blood oxygen credibility requirement, and the continuous duration exceeds the fourth duration, the acquisition of blood oxygen data is triggered, and an alarm message is generated to suspend the adjustment of the inhaled oxygen concentration.

[0485] Optionally, the processor 1602 for determining a blood oxygen change trend based on a specified blood oxygen zone is specifically configured to:

[0486] Determine a first blood oxygen type corresponding to the designated blood oxygen zone and a second blood oxygen type corresponding to the reference blood oxygen zone;

[0487] If the first blood oxygen type is severe hypoxia or severe hyperoxia, determining that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend;

[0488] If the first blood oxygen type is more severe than the blood oxygen type indicated by the second blood oxygen type, determining that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend, the blood oxygen type including at least severe hypoxia, severe hyperoxia, moderate hypoxia, moderate hyperoxia, mild hypoxia, mild hyperoxia, and normal state;

[0489] If the first blood oxygen type and the second blood oxygen type are consistent and neither is severe hypoxia or severe hyperoxia, determining that the blood oxygen change trend within the current adjustment interval is a blood oxygen stable trend;

[0490] If the first blood oxygen type tends to improve relative to the blood oxygen type indicated by the second blood oxygen type, it is determined that the blood oxygen change trend within the current adjustment interval is a blood oxygen improvement trend.

[0491] It should be noted that the processor 1602 that determines the blood oxygen change trend based on the specified blood oxygen partition can also execute the method for determining the blood oxygen change trend based on the specified blood oxygen partition disclosed in the above embodiment of the present invention.

[0492] If the blood oxygen change trend is a deteriorating blood oxygen trend, determining a corresponding adjustment strategy based on the blood oxygen change trend, and adjusting the inhaled oxygen concentration according to the adjustment strategy, the processor 1602 is specifically configured to:

[0493] If the blood oxygen deterioration trend tends to severe hypoxia or severe hyperoxia, the inhaled oxygen concentration is adjusted according to the preset maximum single oxygen concentration adjustment amount, and the duration of the next adjustment interval is changed to the fifth duration. The preset maximum single oxygen concentration adjustment amount is set to different amounts based on different patient types, and the fifth duration is shorter than the duration of the regular adjustment interval;

[0494] If the blood oxygen deterioration trend does not tend toward severe hypoxia or severe hyperoxia, a first oxygen concentration target adjustment amount is obtained based on an offset amount of the blood oxygen data in the designated blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone, a blood oxygen change rate during the last adjustment of the inspired oxygen concentration, and the preset maximum single oxygen concentration adjustment amount.

[0495] When the first oxygen concentration target adjustment amount is less than or equal to the preset maximum single oxygen concentration adjustment amount, adjusting the inhaled oxygen concentration with the first oxygen concentration target adjustment amount;

[0496] When the first oxygen concentration target adjustment amount is greater than the preset maximum single oxygen concentration adjustment amount, the inhaled oxygen concentration is adjusted with the preset maximum single oxygen concentration adjustment amount, and the difference between the first oxygen concentration target adjustment amount and the preset maximum single oxygen concentration adjustment amount is used as the remaining adjustment amount and added to the cumulative adjustment amount of the specified blood oxygen zone.

[0497] If the blood oxygen change trend is a blood oxygen stabilization trend or a blood oxygen improvement trend, the processor for adjusting the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend is specifically configured to:

[0498] If the offset of the blood oxygen data in the designated blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone becomes smaller or remains unchanged, the preset adjustment amount is added to the adjustment amount of the inhaled oxygen concentration within the adjustment interval when the last blood oxygen change trend was a blood oxygen stabilization trend or a blood oxygen improvement trend to obtain a second oxygen concentration target adjustment amount, and the inhaled oxygen concentration is adjusted based on the second oxygen concentration target adjustment amount, and the second oxygen concentration target adjustment amount is not greater than the preset minimum oxygen concentration adjustment amount.

[0499] If the blood oxygen change trend is a stable blood oxygen trend, the processor 1602 adjusts the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend, specifically for:

[0500] If the offset of the blood oxygen data in the specified blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone becomes larger, a third oxygen concentration target adjustment amount is obtained based on the offset of the blood oxygen data in the specified blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone and the cumulative adjustment amount of the specified blood oxygen zone, and the inhaled oxygen concentration is adjusted based on the third oxygen concentration target adjustment amount.

[0501] If the blood oxygen change trend is a stable blood oxygen trend, the processor 1602 adjusts the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend, specifically for:

[0502] If the blood oxygen data is within the blood oxygen data range of the treatment target partition, determine the region where the blood oxygen data is located in the treatment target partition, where the region includes at least a downstream region, a midstream region, and an upstream region;

[0503] If the blood oxygen data is in the downstream area, maintain the current adjustment of the inhaled oxygen concentration;

[0504] If the blood oxygen data is in the middle range, the first timer is started. When the first timer ends, the inhaled oxygen concentration is adjusted according to the preset minimum oxygen concentration adjustment amount.

[0505] If the blood oxygen data is in the upstream area, a second timing is started. When the second timing ends, the inhaled oxygen concentration is adjusted according to the preset minimum oxygen concentration adjustment amount, and the second timing is greater than the first timing.

[0506] based on Figure 16 In one embodiment of the disclosed respiratory support device, the processor 1602 obtains the patient's blood oxygen data in real time based on its own configured sensors or interconnected external detection equipment, and controls the ventilation device 1601 to periodically perform an inhaled oxygen concentration adjustment operation at a fixed interval based on the blood oxygen data to adjust the oxygen concentration in the inhaled gas.

[0507] In a specific implementation, processor 1602 is configured to determine, during a current inspired oxygen concentration adjustment cycle, a blood oxygen zone corresponding to the patient's blood oxygen data acquired in real time. The blood oxygen zone is pre-divided based on blood oxygen saturation and includes a treatment target zone. During treatment of the patient, the patient's corresponding physiological parameters need to be restored to or maintained within the treatment target zone. When the corresponding physiological parameters are within the treatment target zone, the physiological parameters are considered to be in a normal state.

[0508] Processor 1602 is configured to determine a blood oxygen change trend of the patient based on the blood oxygen zone corresponding to the patient's real-time blood oxygen data; and when it is determined that the blood oxygen change trend of the patient is gradually deviating from the treatment target zone, perform an inhaled oxygen concentration adjustment operation in advance to adjust the patient's blood oxygen level to within the treatment target zone.

[0509] The technical solutions and implementation principles involved in the processor in the respiratory support device disclosed in the above embodiment of the present application can be found in the corresponding parts of the method for adjusting the inhaled oxygen concentration disclosed in the above embodiment of the present application. Similarly, the implementation principles of the inhaled oxygen concentration adjustment operation involved in the ventilation device in the respiratory support device disclosed in the above embodiment of the present application can be found in the implementation principles of the inhaled oxygen concentration adjustment operation disclosed in the method for adjusting the inhaled oxygen concentration disclosed in the above embodiment of the present application.

[0510] In the respiratory support device disclosed in the embodiments of the present application, the severity of the patient's blood oxygen status is identified by changes in the severity of the blood oxygen status of the blood oxygen zone where the blood oxygen data is located. Therefore, when subsequently adjusting the inhaled oxygen concentration, different adjustment strategies can be determined based on the severity of the blood oxygen status corresponding to the blood oxygen zone, and the inhaled oxygen concentration should be adjusted promptly according to the corresponding adjustment strategy. This can achieve the purpose of more accurately and quickly responding to rapid changes in the patient's blood oxygen level and adjusting the inhaled oxygen concentration.

[0511] The present application also provides another method for adjusting the concentration of inhaled oxygen, which can also be applied to the respiratory support device disclosed in the above embodiment of the present application. Figure 17 As shown, the method for adjusting the inhaled oxygen concentration mainly includes the following steps:

[0512] Step 1701: Ventilate the patient with gas of a preset oxygen concentration.

[0513] Step 1702: Acquire blood oxygen data in real time.

[0514] Step 1703: Determine the triggering moment for adjusting the inhaled oxygen concentration based on the blood oxygen data acquired in real time.

[0515] During the specific execution of steps 1701 to 1703, the patient is ventilated with gas of a preset oxygen concentration. During the ventilation process, blood oxygen data is obtained in real time, and then the real-time obtained blood oxygen data is processed to determine the patient's current blood oxygen content. If the real-time monitoring shows that the current blood oxygen content is abnormal, the triggering moment for adjusting the inhaled oxygen concentration operation is determined based on the currently obtained blood oxygen data.

[0516] Optionally, a triggering moment for adjusting the inspired oxygen concentration within a current observation window is determined based on the real-time acquired blood oxygen data, wherein the triggering moment is between a minimum duration threshold and a maximum duration threshold of the observation window.

[0517] Optionally, in the current observation window, when the triggering moment for adjusting the inhaled oxygen concentration operation in the current observation window is not determined based on the real-time acquired blood oxygen data, the current observation window is ended and the next observation window is entered when the current observation window reaches a preset duration.

[0518] In the embodiment of the present application, the operation of adjusting the inhaled oxygen concentration may optionally be performed by adopting a corresponding adjustment strategy based on a change trend of the blood oxygen data in the current observation window.

[0519] For specific adjustment strategies, please refer to the adjustment strategies disclosed in the above embodiments of the present invention.

[0520] Step 1704: When the trigger moment is reached, the inhaled oxygen concentration is adjusted, and after the inhaled oxygen concentration adjustment operation is completed, the blood oxygen data is continued to be acquired in real time and the next trigger moment of the inhaled oxygen concentration adjustment operation is determined.

[0521] During the execution of step 1704, optionally, when the inhaled oxygen concentration adjustment operation is completed at the triggering moment of the current observation window, the current observation window is ended and the next observation window is entered to continue acquiring blood oxygen data and determining the next triggering moment for adjusting the inhaled oxygen concentration operation.

[0522] In another embodiment, in addition to obtaining the blood oxygen data, device operating parameters of the respiratory support device and / or physiological parameters of the patient are also obtained.

[0523] Then, based on the real-time acquired blood oxygen data, as well as the device operating parameters and / or the pathological parameters, a triggering moment for adjusting the inhaled oxygen concentration within the current adjustment interval is determined.

[0524] It should be noted that the patient's physiological parameters include but are not limited to those obtained through monitoring equipment such as a pulse oximeter and a monitor.

[0525] In another embodiment, optionally, after obtaining the blood oxygen data of each current adjustment interval in real time, the method further includes:

[0526] Determine whether the blood oxygen data and / or the state of the respiratory support device meet a preset condition. If the preset condition is met, suspend the adjustment of the inhaled oxygen concentration and execute an intervention strategy and / or intervention prompt for the adjustment of the inhaled oxygen concentration.

[0527] The intervention strategy includes: enabling the respiratory support device to maintain the current inhaled oxygen concentration.

[0528] Alternatively, perform an alternate oxygen concentration.

[0529] Alternatively, the oxygen concentration input by the user through a setting interface displaying the oxygen concentration on the user interface is obtained.

[0530] The intervention prompt includes: outputting an alarm message, or outputting a prompt message.

[0531] The alarm information is used to indicate that the blood oxygen data is abnormal and / or to indicate that the respiratory support device is abnormal.

[0532] The prompt information is used to indicate the suspension of adjustment of the inhaled oxygen concentration, and / or is used to indicate the status of a setting interface for displaying oxygen concentration on a user interface of the respiratory support device.

[0533] In the specific process of implementing the intervention prompt, first indication information for indicating suspension of inhaled oxygen concentration adjustment and / or second indication information for indicating the reason for suspension are displayed on the information prompt area of the respiratory support device;

[0534] The information prompt display area is composed of one information display area, or is composed of two independent information sub-display areas, one information sub-display area is used to display the first indication information, and the other information sub-display area is used to display the second indication information.

[0535] It should be noted that the status information of the setting interface displaying the oxygen concentration on the user interface of the respiratory support device includes but is not limited to display status change information.

[0536] The display status change information includes but is not limited to: changing the background color, or displaying manual setting information.

[0537] The manual setting prompt information includes a character string and / or text.

[0538] The method for adjusting the inhaled oxygen concentration disclosed in the embodiments of the present application obtains blood oxygen data in real time, and then determines the triggering time for adjusting the inhaled oxygen concentration based on the real-time blood oxygen data, thereby determining the triggering time for adjusting the inhaled oxygen concentration according to the patient's current blood oxygen content, thereby achieving dynamic adjustment of the inhaled oxygen concentration.

[0539] Based on the method for adjusting the inhaled oxygen concentration provided in the above-mentioned embodiment of the present application, the embodiment of the present application also discloses a respiratory support device. In one embodiment, the respiratory support device can be a ventilator.

[0540] The respiratory support device includes a ventilation device and a processor.

[0541] The ventilation device is used for providing inhalation gas to a patient through a breathing circuit and breathing accessories, wherein the inhalation gas is oxygen-containing gas.

[0542] The processor is connected to the ventilation device by signal so as to control the flow rate of the inhaled gas provided by the ventilation device to the patient.

[0543] The processor is further configured to:

[0544] Ventilate the patient with a preset oxygen concentration gas;

[0545] Obtain blood oxygen data in real time;

[0546] Determining the triggering moment for adjusting the inhaled oxygen concentration based on the real-time acquired blood oxygen data;

[0547] When the trigger moment is reached, the inhaled oxygen concentration is adjusted, and after the inhaled oxygen concentration adjustment operation is completed, the blood oxygen data is continuously acquired in real time and the next trigger moment of the inhaled oxygen concentration adjustment operation is determined.

[0548] In one embodiment, the processor for determining the triggering moment for adjusting the inhaled oxygen concentration based on the real-time acquired blood oxygen data is specifically configured to:

[0549] The triggering moment for adjusting the inhaled oxygen concentration operation within the current observation window is determined based on the real-time acquired blood oxygen data.

[0550] In one embodiment, the processor is further configured to:

[0551] At the triggering moment of the current observation window, when the inhaled oxygen concentration adjustment operation is completed, the current observation window ends and the next observation window begins.

[0552] In one embodiment, the processor is further configured to:

[0553] Acquiring device operating parameters of the respiratory support device and / or physiological parameters of the patient;

[0554] The triggering moment for adjusting the inhaled oxygen concentration within the current adjustment interval is determined based on the blood oxygen data acquired in real time, as well as the device operating parameters and / or the pathological parameters.

[0555] In one embodiment, the processor is further configured to:

[0556] After acquiring each blood oxygen data of the current adjustment interval in real time, determining whether the blood oxygen data and / or the state of the respiratory support device meet a preset condition;

[0557] If the preset conditions are met, the adjustment of the inhaled oxygen concentration is suspended, and the intervention strategy and / or intervention prompt for the adjustment of the inhaled oxygen concentration is executed;

[0558] Wherein, the intervention strategy includes: enabling the respiratory support device to maintain the current inspired oxygen concentration;

[0559] Alternatively, implement an alternate oxygen concentration;

[0560] Or, obtaining the oxygen concentration input by the user through a setting interface displaying oxygen concentration on the user interface;

[0561] The intervention prompt includes: outputting alarm information, or outputting prompt information;

[0562] The alarm information is used to indicate that the blood oxygen data is abnormal and / or to indicate that the respiratory support device is abnormal;

[0563] The prompt information is used to indicate the suspension of adjustment of the inhaled oxygen concentration, and / or is used to indicate the status of a setting interface for displaying oxygen concentration on a user interface of the respiratory support device.

[0564] It should be noted that the respiratory support device disclosed in the embodiment of the present application can also perform the aforementioned Figure 1 A method for regulating the concentration of inhaled oxygen is disclosed.

[0565] The various embodiments of the present invention are described in a progressive manner, with each embodiment focusing on the differences from the other embodiments. Reference can be made to the common and similar parts between the various embodiments. For the devices disclosed in the embodiments, since they correspond to the methods disclosed in the embodiments, the description is relatively simple, and the relevant parts can be referred to the method description.

[0566] The above description of the disclosed embodiments is intended to enable one skilled in the art to implement or use the present invention. Various modifications to these embodiments will be readily apparent to one skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention is not limited to the embodiments shown herein but is intended to conform to the widest scope consistent with the principles and novel features disclosed herein.

[0567] The above description of the disclosed embodiments will enable one skilled in the art to implement or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention is not limited to the embodiments shown herein, but is to be construed in the widest manner consistent with the principles and novel features disclosed herein.

[0568] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as within the scope of protection of the present invention.

Claims

1. A respiratory support device, characterized in that include: A ventilation device for providing an inhalation gas to a patient through a breathing circuit and a breathing accessory, wherein the inhalation gas is an oxygen-containing gas; a processor, the processor being signal-connected to the ventilator to control the flow rate of inhaled gas provided by the ventilator to the patient; The processor is further configured to: Obtain the blood oxygen data of each adjustment interval in real time and determine the recommended blood oxygen zone where each blood oxygen data is located; determining whether the severity of each blood oxygen data satisfies a condition for triggering early adjustment of the inhaled oxygen concentration, where the severity refers to the degree to which the blood oxygen data deviates from the treatment target zone, the condition for triggering early adjustment of the inhaled oxygen concentration including an increasing severity, and the recommended blood oxygen zone and the treatment target zone each corresponding to a pre-divided blood oxygen data range; If the condition for triggering the adjustment of the inhaled oxygen concentration in advance is met, the operation of adjusting the inhaled oxygen concentration is performed; otherwise, the operation of adjusting the inhaled oxygen concentration is performed normally; The processor determines whether the severity of each blood oxygen data satisfies the condition for triggering the adjustment of the inhaled oxygen concentration in advance, specifically for: Obtaining a reference blood oxygen partition containing blood oxygen data with the greatest severity within a previous adjustment interval, where the previous adjustment interval and the current adjustment interval are not necessarily the same in duration; and comparing in real time the severity of the blood oxygen data obtained within the current adjustment interval with the severity of the blood oxygen data of the reference blood oxygen partition; Before the timing of the current adjustment interval ends, the number of blood oxygen data obtained in the current adjustment interval whose severity is greater than the severity of the blood oxygen data of the reference blood oxygen zone exceeds a preset number, and the condition for early triggering the adjustment of the inhaled oxygen concentration is met; otherwise, the condition for early triggering the adjustment of the inhaled oxygen concentration is not met.

2. The device according to claim 1, characterized in that The processor for determining whether the severity of each blood oxygen data satisfies the condition for triggering the adjustment of the inhaled oxygen concentration in advance is further configured to: Starting from the start time of the current adjustment interval, at every first duration, determining whether the severity of the blood oxygen data corresponding to each acquired blood oxygen data continuously increases, the first duration being less than the duration of the current adjustment interval; If there is a continuous increase, the condition for triggering the adjustment of the inhaled oxygen concentration in advance is met; otherwise, the condition for triggering the adjustment of the inhaled oxygen concentration in advance is not met.

3. The device according to claim 1, characterized in that The processor is further configured to: Determine in real time whether the duration of each blood oxygen data in the selected blood oxygen zone is less than or equal to the second duration for a third duration, and the third duration is greater than the second duration and less than or equal to the duration of the current adjustment interval; If it has lasted for the third time, the adjustment of the inhaled oxygen concentration is triggered according to the adjustment strategy corresponding to the uncertain blood oxygen triggering mode. Otherwise, it is continued to determine whether the severity of each blood oxygen data meets the conditions for triggering the adjustment of the inhaled oxygen concentration in advance.

4. The device according to any one of claims 1, characterized in that The processor is further configured to: Obtain associated data affecting the blood oxygen credibility from the blood oxygen data; determine whether the associated data meets the blood oxygen credibility requirement; if so, determine the blood oxygen partition corresponding to the blood oxygen data; if not, continue to obtain blood oxygen data.

5. The device according to claim 4, characterized in that If the associated data includes at least pulse rate and / or perfusion index and / or blood oxygen signal quality, the processor determines whether the associated data meets the blood oxygen credibility requirement, specifically for: determining whether the pulse rate change rate is higher than a pulse rate change rate threshold; If the pulse rate change rate is higher than the pulse rate change rate threshold, the pulse rate does not meet the blood oxygen credibility requirement; otherwise, the pulse rate meets the blood oxygen credibility requirement; and / or, determining whether the pulse rate is lower than a pulse rate threshold; If the pulse rate is lower than the pulse rate threshold, the pulse rate does not meet the blood oxygen credibility requirement; otherwise, the pulse rate meets the blood oxygen credibility requirement; and / or, determining whether the perfusion index is lower than a perfusion index threshold; If the perfusion index is lower than the perfusion index threshold, the perfusion index does not meet the blood oxygen credibility requirement; otherwise, the perfusion index meets the blood oxygen credibility requirement; and / or, determining whether the blood oxygen signal quality is lower than a blood oxygen signal quality threshold; If the blood oxygen signal quality is lower than the blood oxygen signal quality threshold, the blood oxygen signal quality does not meet the blood oxygen credibility requirement; otherwise, the blood oxygen signal quality meets the blood oxygen credibility requirement.

6. The device according to claim 4, characterized in that The processor is further configured to: If it is continuously determined that the associated data does not meet the blood oxygen credibility requirement, and the continuous time exceeds a fourth time, an alarm message for suspending the adjustment of the inhaled oxygen concentration is generated.

7. The device according to claim 6, characterized in that The processor is further configured to: Based on the alarm string and / or alarm sound displayed on the system operation interface, the user is prompted that the automatic adjustment of the current inhaled oxygen concentration is in a suspended state; And / or, the processor generates an alarm message for suspending adjustment of the inhaled oxygen concentration, specifically for: The reason for suspending the adjustment of the intake oxygen concentration is suggested based on the determination result using the associated data.

8. The device according to claim 6, characterized in that The processor is further configured to: After the alarm prompt is executed, authorize or start the user to manually set the inhaled oxygen concentration; After the blood oxygen data is restored to be credible, the new inhaled oxygen concentration manually set by the user is used as a control value, and based on the control value, each blood oxygen data of the current adjustment interval is acquired in real time.

9. The device according to any one of claims 1 to 8, characterized in that The processor for performing the operation of adjusting the inhaled oxygen concentration is specifically configured to: Obtaining a designated blood oxygen partition for the current adjustment interval, where the designated blood oxygen partition refers to a recommended blood oxygen partition containing the most severe blood oxygen data among the blood oxygen partitions determined within the current adjustment interval; A blood oxygen change trend is determined based on the designated blood oxygen zone, and the inhaled oxygen concentration is adjusted according to a regulation strategy corresponding to the blood oxygen change trend.

10. The device according to claim 9, characterized in that The processor for determining the blood oxygen change trend based on the designated blood oxygen zone is specifically configured to: Determining a first blood oxygen type corresponding to the designated blood oxygen zone and a second blood oxygen type corresponding to the reference blood oxygen zone; If the first blood oxygen type is severe hypoxia or severe hyperoxia, determining that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend; If the first blood oxygen type is more severe than the blood oxygen type indicated by the second blood oxygen type, determining that the blood oxygen change trend within the current adjustment interval is a blood oxygen deterioration trend, the blood oxygen type including at least severe hypoxia, severe hyperoxia, moderate hypoxia, moderate hyperoxia, mild hypoxia, mild hyperoxia, and normal state; If the first blood oxygen type and the second blood oxygen type are consistent and neither is severe hypoxia or severe hyperoxia, determining that the blood oxygen change trend within the current adjustment interval is a blood oxygen stable trend; If the first blood oxygen type tends to improve relative to the blood oxygen type indicated by the second blood oxygen type, it is determined that the blood oxygen change trend within the current adjustment interval is a blood oxygen improvement trend.

11. The device according to claim 10, characterized in that If the blood oxygen change trend is a deteriorating blood oxygen trend, the processor for adjusting the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend is specifically configured to: If the blood oxygen deterioration trend leans toward severe hypoxia or severe hyperoxia, the inhaled oxygen concentration is adjusted according to a preset maximum single oxygen concentration adjustment amount, and the duration of the next adjustment interval is changed to a fifth duration. The preset maximum single oxygen concentration adjustment amount is set to a different adjustment amount based on different patient types, and the fifth duration is shorter than the duration of the regular adjustment interval. If the blood oxygen deterioration trend does not tend toward severe hypoxia or severe hyperoxia, a first oxygen concentration target adjustment amount is obtained based on an offset amount of the blood oxygen data in the designated blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone, a blood oxygen change rate during the last adjustment of the inspired oxygen concentration, and the preset maximum single oxygen concentration adjustment amount. When the first oxygen concentration target adjustment amount is less than or equal to the preset maximum single oxygen concentration adjustment amount, adjusting the inhaled oxygen concentration with the first oxygen concentration target adjustment amount; When the first oxygen concentration target adjustment amount is greater than the preset maximum single oxygen concentration adjustment amount, the inhaled oxygen concentration is adjusted with the preset maximum single oxygen concentration adjustment amount, and the difference between the first oxygen concentration target adjustment amount and the preset maximum single oxygen concentration adjustment amount is used as the remaining adjustment amount and added to the cumulative adjustment amount of the designated blood oxygen zone.

12. The device according to claim 10, characterized in that If the blood oxygen change trend is a blood oxygen stabilization trend or a blood oxygen improvement trend, the processor for adjusting the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend is specifically configured to: If the offset of the blood oxygen data in the designated blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone becomes smaller or remains unchanged, the preset adjustment amount is added to the adjustment amount of the inhaled oxygen concentration within the adjustment interval when the last blood oxygen change trend was a blood oxygen stabilization trend or a blood oxygen improvement trend to obtain a second oxygen concentration target adjustment amount, and the inhaled oxygen concentration is adjusted based on the second oxygen concentration target adjustment amount, and the second oxygen concentration target adjustment amount is not greater than the preset minimum oxygen concentration adjustment amount.

13. The device according to claim 10, characterized in that If the blood oxygen change trend is a stable blood oxygen trend, the processor for adjusting the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend is specifically configured to: If the offset of the blood oxygen data in the specified blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone becomes larger, a third oxygen concentration target adjustment amount is obtained based on the offset of the blood oxygen data in the specified blood oxygen zone from the upper and lower blood oxygen data boundaries of the treatment target zone and the cumulative adjustment amount of the specified blood oxygen zone, and the inhaled oxygen concentration is adjusted based on the third oxygen concentration target adjustment amount.

14. The device according to claim 10, characterized in that If the blood oxygen change trend is a stable blood oxygen trend, the processor for adjusting the inhaled oxygen concentration according to the adjustment strategy corresponding to the blood oxygen change trend is specifically configured to: If the blood oxygen data is within the blood oxygen data range of the treatment target partition, determining the region where the blood oxygen data is located in the treatment target partition, the region including at least a downstream region, a midstream region, and an upstream region; If the blood oxygen data is in the downstream area, maintaining the current adjustment of the inhaled oxygen concentration; If the blood oxygen data is in the midstream range, a first timer is started, and when the first timer ends, the inhaled oxygen concentration is adjusted according to a preset minimum oxygen concentration adjustment amount; If the blood oxygen data is in the upstream area, a second timer is started. When the second timer ends, the inhaled oxygen concentration is adjusted according to a preset minimum oxygen concentration adjustment amount, and the second timer is greater than the first timer.

15. The device according to claim 1, characterized in that The processor is further configured to: When the result of adjusting the inhaled oxygen concentration reaches the upper limit of the oxygen concentration range set by the user, and the duration of the patient's blood oxygen data being lower than the blood oxygen data indicated by the treatment target partition exceeds a fifth duration, executing a status prompt, the status prompt at least comprising: displaying status prompt information indicating that the patient's blood oxygen data is low in a status prompt area pre-demarcated on the user interface of the respiratory support device, the status prompt information at least comprising a character string, text, image and / or sound; After the status prompt is executed, when the duration of the patient's blood oxygen data being lower than the blood oxygen data indicated by the treatment target zone exceeds a sixth duration, continuing to execute the operation of adjusting the inhaled oxygen concentration; or, When the result of adjusting the inhaled oxygen concentration reaches the lower limit of the oxygen concentration range set by the user, and the duration of the patient's blood oxygen data being higher than the blood oxygen data indicated by the treatment target partition exceeds a fifth duration, executing a status prompt, the status prompt at least comprising: displaying status prompt information indicating that the patient's blood oxygen data is high in a status prompt area pre-demarcated on the user interface of the respiratory support device, the status prompt information at least comprising a character string, text, image and / or sound; After the status prompt is executed, when the duration of time during which the patient's blood oxygen data is higher than the blood oxygen data indicated by the treatment target partition exceeds a sixth duration, the operation of adjusting the inhaled oxygen concentration is continued.

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