A reaction chamber structure for a fully automatic chemiluminescence analyzer
By designing a breath stirring structure and a double-layer air chamber structure without external stirring in a fully automatic chemiluminescence detector, the problems of reaction cup pollution and inaccurate temperature control are solved, and higher measurement accuracy and temperature control accuracy are achieved.
Patent Information
- Application Number
- CN202211692163.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-12-28
- Publication Date
- 2025-07-29
- Estimated Expiration
- 2042-12-28
AI Technical Summary
The incubation reaction chamber of the existing fully automatic chemiluminescence measuring instrument is prone to contamination of the reaction cup during the stirring process, and the temperature control is not accurate enough.
A reaction chamber structure including a incubation reaction chamber, a silo cover, a incubation plate, a incubation cup hole, a reaction cup, a stirring rod, a silo base plate and a telescopic drive cylinder is designed. The breathing and stirring structure and a double-layer air chamber structure are adopted. The stirring rod is driven by a telescopic drive cylinder and the stirring rod without external stirring, and the double-layer air chamber structure is used for rapid and uniform temperature control.
It reduces the risk of reaction cup contamination, improves the accuracy of measurement and temperature control, and achieves a fast and uniform temperature distribution and cooling rate.
Smart Images

Figure CN116256526B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of chemiluminescence determination, and particularly to a reaction chamber structure for a full-automatic chemiluminescence analyzer. Background Art
[0002] The full-automatic chemiluminescence analyzer is the latest immunoassay technology developed after radioimmunoassay, enzyme immunoassay, fluorescence immunoassay, and time-resolved fluorescence immunoassay. It combines the highly sensitive chemiluminescence determination technology with the highly specific immune reaction and is used for the detection and analysis of various antigens, haptens, antibodies, hormones, enzymes, fatty acids, vitamins, drugs, etc. The reaction chamber inside the full-automatic chemiluminescence analyzer is a temperature-controlled cultivation mechanism for cultivating the samples and reagents inside the reaction cups at a certain temperature. For example, a full-automatic chemiluminescence analyzer disclosed in Chinese invention patent CN105628687B records that: the incubation device includes an incubation plate, a conductive slip ring, a turntable motor, a heating sheet, a temperature sensor, and an incubation plate bracket. The incubation plate is arranged on the incubation plate bracket, and the back of the incubation plate is provided with a heating sheet and a temperature sensor; the conductive slip ring is arranged at the center of the incubation plate, and the wires of the heating sheet and the temperature sensor are both wound on the conductive slip ring; the rotating shaft of the turntable motor is connected to the center of the incubation plate; several reaction cup holes are arranged on the circular edge of the incubation plate... The incubation plate motor rotates to the position of the stirring assembly for stirring and incubation;
[0003] For the incubation reaction chamber in the prior art, as recorded in the above patent, during use, it is necessary to insert the stirring assembly inside the full-automatic chemiluminescence analyzer into the reaction cup for stirring. During this process, the risk of contamination of the reaction cup will be greatly increased. Summary of the Invention
[0004] The purpose of the present invention is to provide a reaction chamber structure for a full-automatic chemiluminescence analyzer to solve the problems raised in the above background art.
[0005] To achieve the above object, the present invention provides the following technical solution: A reaction chamber structure for a fully automatic chemiluminescence analyzer, comprising a incubation reaction chamber, a chamber cover, an incubation plate, incubation cup holes, reaction cups, stirring push rods, push rod substrates, and telescopic drive cylinders. The chamber cover is slidably disposed above the incubation reaction chamber. The incubation plate is fixedly disposed inside the incubation reaction chamber. Incubation cup holes are vertically penetrated inside the incubation plate. The reaction cups are inserted inside the incubation cup holes. A breathing and stirring structure is disposed inside the reaction cups. The stirring push rods are disposed below the incubation plate. The stirring push rods and the incubation cup holes are coaxially corresponding one by one. The lower end of the stirring push rod is fixedly provided with a push rod substrate. A telescopic drive cylinder is fixedly disposed between the push rod substrate and the inner lower surface of the incubation reaction chamber. The telescopic drive cylinder can drive the stirring push rod to move up and down. During the up and down movement of the stirring push rod, it cooperates with the breathing and stirring structure to stir the liquid inside the reaction cup.
[0006] A double-layer air cavity structure with a folding-back function is disposed inside and outside the incubation plate. An extrusion heat conduction structure is disposed on the inner wall and the lower position of the incubation cup hole. The extrusion heat conduction structure has a locking function and can fix the reaction cup inside the incubation cup hole.
[0007] The breathing and stirring structure includes a cup bottom partition plate, a liquid inlet hole, a liquid discharge hole, a one-way diaphragm, a sealing plug, a sealing rubber ring, an inner folding eaves, and a return spring.
[0008] The cup bottom partition plate is fixedly disposed inside the reaction cup near the lower position. The liquid inlet hole is vertically penetrated through the surface of the cup bottom partition plate near the edge position. The liquid discharge hole is vertically penetrated through the center position of the cup bottom partition plate. One-way diaphragms are respectively disposed above the liquid discharge hole and below the liquid inlet hole. A sealing plug is movably disposed below the cup bottom partition plate. A sealing rubber ring is embedded and fixed on the side wall surface of the sealing plug. The sealing rubber ring is in sealed contact with the inner wall surface of the reaction cup. The lower end of the reaction cup is fixedly provided with an inner folding eaves. A return spring is connected between the inner folding eaves and the sealing plug.
[0009] The double-layer air cavity structure includes an air inlet communication groove, an air outlet communication groove, an interaction groove, a lower branch cavity, an upper branch cavity, a temperature control air inlet pipe, an exhaust seat, and an exhaust hole.
[0010] An air inlet communication groove and an exhaust communication groove are formed near one side inside the incubation plate. The air inlet communication groove and the exhaust communication groove are arranged vertically. An interaction groove is formed near the other side inside the incubation plate. The air inlet communication groove is communicated with the interaction groove through a lower branch cavity, and the exhaust communication groove is communicated with the interaction groove through an upper branch cavity. Both the lower branch cavity and the upper branch cavity are arranged parallel to the upper and lower surfaces of the incubation plate. A temperature control air inlet pipe and an exhaust seat are fixedly arranged on the outer surface of the incubation plate. The temperature control air inlet pipe is communicated with the air inlet communication groove. An exhaust hole is formed inside the exhaust seat, and the exhaust hole is communicated with the exhaust communication groove.
[0011] The extrusion heat conduction structure includes an inner wall ring groove, a rubber film, a silicone grease communication cavity, a silicone grease driving cavity, a piston ring, a ring side rubber sleeve, an extrusion spring, a column hole, a pushing column rod, a synchronous bottom ring, a locking push plate, a through slot hole, a locking telescopic cylinder and an inner wall support plate.
[0012] The inner wall ring groove is circular and is formed on the inner wall surface of the incubation cup hole. A rubber film is arranged at the opening of the inner wall ring groove. The rubber film and the inner wall ring groove cooperate to form a closed space. A silicone grease communication cavity and a silicone grease driving cavity are formed inside the incubation plate. The silicone grease driving cavity is communicated with the above-mentioned closed space through the silicone grease communication cavity. The silicone grease driving cavity is circular. Heat-conducting silicone grease is filled inside the silicone grease driving cavity, the silicone grease communication cavity and the above-mentioned closed space.
[0013] A piston ring is arranged to move up and down inside the silicone grease driving cavity. Ring side rubber sleeves are respectively sleeved and fixed on the inner and outer surface positions of the piston ring. The ring side rubber sleeves are in sealed contact with the inner wall surface of the silicone grease driving cavity. An extrusion spring is arranged above the piston ring, and the extrusion spring is in a compressed state. A column hole is communicated below the silicone grease driving cavity. A pushing column rod is inserted inside the column hole. The upper end of the pushing column rod is fixedly installed with the piston ring, and the lower end of the pushing column rod is fixedly provided with a synchronous bottom ring. A locking push plate is arranged below the synchronous bottom ring. A through slot hole is formed through the surface of the locking push plate, and the through slot hole corresponds to the incubation cup hole one by one coaxially. An inner wall support plate is fixedly arranged on the inner wall surface position of the incubation reaction chamber. A locking telescopic cylinder is fixedly arranged on the upper surface of the inner wall support plate, and the locking telescopic cylinder drives the locking push plate to move up and down.
[0014] An electric control fixing edge is fixedly arranged on the upper surface of the chamber cover, and a temperature sensor is embedded and fixed on the surface of the incubation plate.
[0015] Compared with the prior art, the beneficial effects of the present invention are:
[0016] Compared with the incubation reaction chamber in the traditional fully automatic chemiluminescence analyzer, the reaction chamber structure of the present invention does not require the insertion of an external stirring component when stirring the sample reagent in the reaction cup, which can greatly reduce the possibility of contamination of the sample reagent, thereby improving the measurement accuracy of the chemiluminescence analyzer.
[0017] Moreover, the extruded heat-conducting structure can lock and fix the reaction cup, thereby preventing the reaction cup from falling off and moving when the reagent is stirred by using the breathing stirring structure; at the same time, the gap between the inner wall surface of the incubation cup hole and the outer surface of the reaction cup can be reduced, so that the two maintain good contact heat conduction performance, thereby improving the temperature control accuracy of the incubation plate on the reaction cup.
[0018] By setting up a double-layer air cavity structure, the temperature control response of the incubation plate can be faster and the temperature distribution can be more uniform. Compared with the traditional heating method of using a heating plate and an incubation plate in close contact, the double-layer air cavity structure of the present invention uses the heated air flow to travel inside the incubation plate, which can make the heated air flow quickly pass through various parts of the incubation plate when the temperature rises, thereby heating faster and more evenly. And by using the double-layer structure, the air flow is reversed, which can weaken the uneven effect caused by the temperature difference between the initial air flow and the final air flow, so that the initial high-temperature air flow and the final low-temperature air flow pass through the upper and lower positions, further improving the uniformity of the overall temperature distribution of the incubation plate. And when cooling, the traditional incubation plate can only cool down by natural heat dissipation, and the rate is relatively low. The double-layer air cavity structure of the present invention directly reduces the temperature of the heated air flow, so that the air flow cools the incubation plate in the opposite direction, thereby improving the cooling rate, and making the temperature control of the entire incubation plate more precise and sensitive. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 It is a schematic diagram of the overall structure of the present invention.
[0020] Figure 2 It is the front view of the overall structure of the present invention.
[0021] Figure 3 It is a three-dimensional half-section schematic diagram of the reaction cup of the present invention.
[0022] Figure 4 for Figure 3 Enlarged schematic diagram of area A in the middle.
[0023] Figure 5 for Figure 4 Enlarged schematic diagram of area B in the middle.
[0024] Figure 6 This is a three-dimensional half-section front view of the reaction cup of the present invention.
[0025] Figure 7 for Figure 6 Enlarged schematic diagram of area C in the middle.
[0026] Figure 8 This is a schematic three-dimensional half-section view of the horizontal angle of the present invention.
[0027] Figure 9 This is a schematic three-dimensional half-section view of the middle position of the present invention.
[0028] Figure 10 This is a top view schematic diagram of the overall structure of the present invention.
[0029] In the figure: 1, incubation reaction chamber; 2, chamber cover; 3, incubation plate; 4, incubation cup holes; 5, reaction cup; 6, stirring ejector rod; 7, ejector rod base plate; 8, telescopic drive cylinder; 501, cup bottom partition disk; 502, liquid inlet hole; 503, liquid discharge hole; 504, one-way diaphragm; 505, sealing push plug; 506, sealing rubber ring; 507, inner folded eaves; 508, reset tension spring; 301, air inlet communication groove; 302, exhaust communication groove; 303, interaction groove; 304, lower branch cavity; 305, upper branch cavity; 306, temperature control air inlet pipe; 307, exhaust seat; 308, exhaust hole; 401, inner wall ring groove; 402, rubber film; 403, silicone grease communication cavity; 404, silicone grease drive cavity; 405, piston ring; 406, ring side rubber sleeve; 407, compression spring; 408, column hole; 409, push column rod; 410, synchronous bottom ring; 411, locking push plate; 412, through slot hole; 413, locking telescopic cylinder; 414, inner wall shelf plate; 201, electric control fixed edge; 309, temperature sensor. Specific embodiments
[0030] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.
[0031] Please refer to Figures 1 to 10, the present invention provides a technical solution: a reaction chamber structure for a fully automatic chemiluminescence analyzer, including a incubation reaction chamber 1, a chamber cover 2, an incubation plate 3, incubation cup holes 4, reaction cups 5, stirring push rods 6, a push rod base plate 7, and a telescopic drive cylinder 8. A chamber cover 2 is slidably arranged above the incubation reaction chamber 1. An incubation plate 3 is fixedly arranged inside the incubation reaction chamber 1. Incubation cup holes 4 are vertically penetrated through the inside of the incubation plate 3. Reaction cups 5 are inserted into the incubation cup holes 4. A breathing and stirring structure is arranged inside the reaction cups 5. A stirring push rod 6 is arranged below the incubation plate 3. The stirring push rods 6 are coaxially corresponding to the incubation cup holes 4 one by one. A push rod base plate 7 is fixedly arranged at the lower end of the stirring push rod 6. A telescopic drive cylinder 8 is fixedly arranged between the push rod base plate 7 and the inner lower surface of the incubation reaction chamber 1. The telescopic drive cylinder 8 can drive the stirring push rod 6 to move up and down. During the up and down movement of the stirring push rod 6, it cooperates with the breathing and stirring structure to stir the liquid inside the reaction cup 5.
[0032] A double-layer air cavity structure with a folding-back function is arranged inside and outside the incubation plate 3. An extrusion heat conduction structure is arranged on the inner wall and the lower position of the incubation cup hole 4. The extrusion heat conduction structure has a locking function and can fix the reaction cup 5 inside the incubation cup hole 4.
[0033] The breathing and stirring structure includes a cup bottom partition plate 501, a liquid inlet hole 502, a liquid discharge hole 503, a one-way diaphragm 504, a sealing push plug 505, a sealing rubber ring 506, an inner folding eaves 507, and a reset tension spring 508.
[0034] The cup bottom partition plate 501 is fixedly arranged inside the reaction cup 5 near the lower position. Liquid inlet holes 502 are vertically penetrated through the surface of the cup bottom partition plate 501 near the edge. A liquid discharge hole 503 is vertically penetrated through the center position of the cup bottom partition plate 501. One-way diaphragms 504 are respectively arranged above the liquid discharge hole 503 and below the liquid inlet hole 502. A sealing push plug 505 is movably arranged below the cup bottom partition plate 501. A sealing rubber ring 506 is embedded and fixed on the side wall surface of the sealing push plug 505. The sealing rubber ring 506 is in sealed contact with the inner wall surface of the reaction cup 5. An inner folding eaves 507 is fixedly arranged at the lower end of the reaction cup 5. A reset tension spring 508 is connected between the inner folding eaves 507 and the sealing push plug 505.
[0035] The double-layer air cavity structure includes an air inlet communication groove 301, an exhaust communication groove 302, an interaction groove 303, a lower branch cavity 304, an upper branch cavity 305, a temperature control air inlet pipe 306, an exhaust seat 307, and an exhaust hole 308.
[0036] An air inlet communication groove 301 and an exhaust communication groove 302 are formed near one side inside the incubation plate 3. The air inlet communication groove 301 and the exhaust communication groove 302 are arranged vertically. An interaction groove 303 is formed near the other side inside the incubation plate 3. The air inlet communication groove 301 communicates with the interaction groove 303 through a lower branch cavity 304, and the exhaust communication groove 302 communicates with the interaction groove 303 through an upper branch cavity 305. Both the lower branch cavity 304 and the upper branch cavity 305 are arranged parallel to the upper and lower surfaces of the incubation plate 3. A temperature-controlled air inlet pipe 306 and an exhaust seat 307 are fixedly arranged on the outer surface of the incubation plate 3. The temperature-controlled air inlet pipe 306 communicates with the air inlet communication groove 301. An exhaust hole 308 is formed inside the exhaust seat 307, and the exhaust hole 308 communicates with the exhaust communication groove 302.
[0037] The extrusion heat conduction structure includes an inner wall ring groove 401, a rubber film 402, a silicone grease communication cavity 403, a silicone grease driving cavity 404, a piston ring 405, a ring side rubber sleeve 406, an extrusion spring 407, a column hole 408, a push column rod 409, a synchronous bottom ring 410, a locking push plate 411, a through slot hole 412, a locking telescopic cylinder 413 and an inner wall support plate 414.
[0038] The inner wall ring groove 401 is circular and is formed on the inner wall surface of the incubation cup hole 4. A rubber film 402 is arranged at the opening of the inner wall ring groove 401. The rubber film 402 and the inner wall ring groove 401 cooperate to form a closed space. A silicone grease communication cavity 403 and a silicone grease driving cavity 404 are formed inside the incubation plate 3. The silicone grease driving cavity 404 communicates with the above-mentioned closed space through the silicone grease communication cavity 403. The silicone grease driving cavity 404 is circular. The inside of the silicone grease driving cavity 404, the silicone grease communication cavity 403 and the above-mentioned closed space are all filled with heat-conducting silicone grease. The heat-conducting silicone grease is in a fluid state and has good heat-conducting performance.
[0039] Inside the silicone grease drive cavity 404, a piston ring 405 is arranged to move up and down. Ring side rubber sleeves 406 are respectively sleeved and fixed on the inner and outer surface positions of the piston ring 405. The ring side rubber sleeves 406 are in sealed contact with the inner wall surface of the silicone grease drive cavity 404. Above the piston ring 405, a compression spring 407 is arranged. The compression spring 407 is in a compressed state. Below the silicone grease drive cavity 404, a column hole 408 is communicated. Inside the column hole 408, a push column rod 409 is inserted. The upper end of the push column rod 409 is fixedly installed with the piston ring 405. The lower end of the push column rod 409 is fixedly provided with a synchronous bottom ring 410. Below the synchronous bottom ring 410, a locking push plate 411 is arranged. Through slots 412 are formed through the surface of the locking push plate 411. The through slots 412 and the incubation cup holes 4 are coaxially corresponding one by one. On the inner wall surface position of the incubation reaction chamber 1, an inner wall shelf plate 414 is fixedly provided. On the upper surface of the inner wall shelf plate 414, a locking telescopic cylinder 413 is fixedly provided. The locking telescopic cylinder 413 drives the locking push plate 411 to move up and down. Both the locking telescopic cylinder 413 and the telescopic drive cylinder 8 can adopt hydraulic, pneumatic or electric control screw rod lifting transmission devices.
[0040] On the upper surface of the chamber cover 2, an electric control fixing edge 201 is fixedly provided. On the surface of the incubation plate 3, a temperature sensor 309 is embedded and fixed. The number of the temperature sensors 309 can be set in multiple groups to improve the detection accuracy.
[0041] When in use, the incubation reaction chamber of the present invention is arranged inside a full-automatic chemiluminescence analyzer. The chamber cover 2 is fixedly installed with the moving structure inside the instrument through the electric control fixing edge 201, so as to control the opening and closing of the chamber cover 2. Inside the full-automatic chemiluminescence analyzer, a blowing device with a temperature control function is arranged, and the blowing device is communicated with the temperature control air inlet pipe 306 through a heat preservation pipeline. The temperature of the incubation plate 3 is detected by the temperature sensor 309, so as to realize closed-loop temperature feedback control.
[0042] The reaction cup 5 is inserted into the incubation cup hole 4 through the clamping mechanism inside the fully automatic chemiluminescence analyzer. When it is necessary to stir the reagent and sample inside the reaction cup 5, first control the locking telescopic cylinder 413 to extend, so that the locking push plate 411 moves upward, pushing the synchronous bottom ring 410 and the pushing column rod 409 upward. At this time, the piston ring 405 moves upward, squeezing the thermal conductive silicone grease inside the silicone grease driving cavity 404 to enter the inner wall ring groove 401 through the silicone grease communication cavity 403, so that the rubber membrane 402 bulges and squeezes against the outer surface of the reaction cup 5, fixing the reaction cup 5. At the same time, the gap between the inner wall surface of the incubation cup hole 4 and the outer surface of the reaction cup 5 is reduced, so that the two maintain good contact thermal conductivity, improving the temperature control accuracy of the incubation plate 3 for the reaction cup 5; the telescopic driving cylinder 8 reciprocates, driving the stirring top rod 6 to move up and down. When the stirring top rod 6 rises, the upper end of the stirring top rod 6 abuts against the lower surface of the sealing plug 505, driving the sealing plug 505 to move upward, so that the liquid between the sealing plug 505 and the cup bottom partition plate 501 sprays upward through the liquid discharge hole 503. When the stirring top rod 6 moves downward, the sealing plug 505 moves downward and resets under the pulling force of the reset spring 508, sucking liquid into the space between the sealing plug 505 and the cup bottom partition plate 501 through the liquid inlet hole 502. In the reciprocating cycle of the above process, the liquid inside the reaction cup 5 is turbulently stirred without the need for foreign objects to be inserted, reducing the possibility of contamination.
[0043] When heating the incubation plate 3, heating air flow is blown into the temperature control air inlet pipe 306 through the air blowing device. The air flow flows through the intake communication groove 301, the lower branch cavity 304, the interaction groove 303, the upper branch cavity 305 and the exhaust communication groove 302 in sequence, and is discharged from the exhaust hole 308, rapidly heating the incubation plate 3. At the same time, the temperature sensor 309 monitors the temperature of the incubation plate 3, and performs real-time closed-loop feedback to maintain a certain temperature range. Through the incubation plate 3, the reaction cup 5 is in the required temperature state, ensuring the progress of the incubation reaction.
[0044] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A reaction chamber structure for a fully automatic chemiluminescence analyzer, comprising a incubation reaction chamber (1), a chamber cover (2), an incubation plate (3), incubation cup holes (4), reaction cups (5), stirring ejector rods (6), an ejector rod base plate (7) and a telescopic drive cylinder (8). A chamber cover (2) is slidably arranged above the incubation reaction chamber (1). An incubation plate (3) is fixedly arranged inside the incubation reaction chamber (1). Incubation cup holes (4) are vertically penetrated and opened inside the incubation plate (3). The reaction cups (5) are inserted inside the incubation cup holes (4). It is characterized in that: Inside the reaction cup (5), a breathing and stirring structure is provided. Below the incubation plate (3), a stirring push rod (6) is provided. The stirring push rod (6) corresponds to the incubation cup holes (4) one by one coaxially. At the lower end of the stirring push rod (6), a push rod base plate (7) is fixedly provided. Between the push rod base plate (7) and the inner lower surface of the incubation reaction chamber (1), a telescopic driving cylinder (8) is fixedly provided. The telescopic driving cylinder (8) can drive the stirring push rod (6) to move up and down. During the up and down movement of the stirring push rod (6), it cooperates with the breathing and stirring structure to stir the liquid inside the reaction cup (5). Inside and outside the incubation plate (3), a double-layer air cavity structure with a folding-back function is provided. On the inner wall and the lower position of the incubation cup hole (4), an extrusion heat conduction structure is provided. The extrusion heat conduction structure has a locking function and can fix the reaction cup (5) inside the incubation cup hole (4). The breathing and stirring structure includes a bottom cup partition (501), a liquid inlet hole (502), a liquid discharge hole (503), a one-way diaphragm (504), a sealing push plug (505), a sealing rubber ring (506), an inner folding eaves (507) and a return spring (508). The bottom cup partition (501) is fixedly provided inside the reaction cup (5) near the lower position. Near the edge of the surface of the bottom cup partition (501), a liquid inlet hole (502) is vertically penetrated. At the central position of the bottom cup partition (501), a liquid discharge hole (503) is vertically penetrated. Above the liquid discharge hole (503) and below the liquid inlet hole (502), one-way diaphragms (504) are respectively provided. Below the bottom cup partition (501), a sealing push plug (505) is movably provided. On the side wall surface position of the sealing push plug (505), a sealing rubber ring (506) is embedded and fixed. The sealing rubber ring (506) is in sealed contact with the inner wall surface of the reaction cup (5). At the lower end of the reaction cup (5), an inner folding eaves (507) is fixedly provided. Between the inner folding eaves (507) and the sealing push plug (505), a return spring (508) is connected.
2. The reaction chamber structure of a fully automatic chemiluminescence analyzer according to claim 1, characterized in that: The double-layer air cavity structure includes an air inlet communication groove (301), an exhaust communication groove (302), an interaction groove (303), a lower branch cavity (304), an upper branch cavity (305), a temperature control air inlet pipe (306), an exhaust seat (307) and an exhaust hole (308).
3. The reaction chamber structure of a fully automatic chemiluminescence analyzer according to claim 2, characterized in that: An air inlet communication groove (301) and an exhaust communication groove (302) are formed near one side inside the incubation plate (3). The air inlet communication groove (301) and the exhaust communication groove (302) are arranged vertically. An interaction groove (303) is formed near the other side inside the incubation plate (3). The air inlet communication groove (301) is communicated with the interaction groove (303) through a lower branch cavity (304), and the exhaust communication groove (302) is communicated with the interaction groove (303) through an upper branch cavity (305). The lower branch cavity (304) and the upper branch cavity (305) are both arranged parallel to the upper and lower surfaces of the incubation plate (3). A temperature control air inlet pipe (306) and an exhaust seat (307) are fixedly arranged on the outer surface of the incubation plate (3). The temperature control air inlet pipe (306) is communicated with the air inlet communication groove (301). An exhaust hole (308) is formed inside the exhaust seat (307), and the exhaust hole (308) is communicated with the exhaust communication groove (302).
4. A reaction chamber structure for a fully automatic chemiluminescence analyzer according to claim 1, characterized in that: The extrusion heat conduction structure includes an inner wall ring groove (401), a rubber film (402), a silicone grease communication cavity (403), a silicone grease driving cavity (404), a piston ring (405), a ring side rubber sleeve (406), an extrusion spring (407), a column hole (408), a push column rod (409), a synchronous bottom ring (410), a locking push plate (411), a through slot hole (412), a locking telescopic cylinder (413) and an inner wall shelf plate (414).
5. A reaction chamber structure for a fully automatic chemiluminescence analyzer according to claim 4, characterized in that: The inner wall ring groove (401) is circular and is formed on the inner wall surface of the incubation cup hole (4). A rubber film (402) is arranged at the opening of the inner wall ring groove (401). The rubber film (402) and the inner wall ring groove (401) cooperate to form a closed space. A silicone grease communication cavity (403) and a silicone grease driving cavity (404) are formed inside the incubation plate (3). The silicone grease driving cavity (404) is communicated with the above-mentioned closed space through the silicone grease communication cavity (403). The silicone grease driving cavity (404) is circular. The silicone grease driving cavity (404), the silicone grease communication cavity (403) and the inside of the above-mentioned closed space are all filled with heat-conducting silicone grease.
6. A reaction chamber structure for a fully automatic chemiluminescence analyzer according to claim 5, characterized in that: Inside the silicone grease drive cavity (404), a piston ring (405) is arranged to move up and down. Ring side rubber sleeves (406) are respectively sleeved and fixed on the inner and outer surface positions of the piston ring (405). The ring side rubber sleeves (406) are in sealed contact with the inner wall surface of the silicone grease drive cavity (404). Above the piston ring (405), a compression spring (407) is arranged. The compression spring (407) is in a compressed state. Below the silicone grease drive cavity (404), a column hole (408) is communicated. Inside the column hole (408), a push column rod (409) is inserted. The upper end of the push column rod (409) is fixedly installed with the piston ring (405). The lower end of the push column rod (409) is fixedly provided with a synchronous bottom ring (410). Below the synchronous bottom ring (410), a locking push plate (411) is arranged. Through holes (412) are penetrated and formed on the surface of the locking push plate (411). The through holes (412) and the incubation cup holes (4) are coaxially corresponding one by one. On the inner wall surface position of the incubation reaction chamber (1), an inner wall support plate (414) is fixedly provided. On the upper surface of the inner wall support plate (414), a locking telescopic cylinder (413) is fixedly provided. The locking telescopic cylinder (413) drives the locking push plate (411) to move up and down.
7. The reaction chamber structure for a fully automatic chemiluminescence analyzer according to claim 1, characterized in that: On the upper surface of the chamber cover (2), an electrically controlled fixing edge (201) is fixedly provided. On the surface of the incubation plate (3), a temperature sensor (309) is embedded and fixed.
Citation Information
Patent Citations
A fully automated chemiluminescence analyzer
CN105628687B
Full-automatic chemiluminiscence tester
CN105628687A
Fully automatic photoexcited chemiluminescence detector
WO2019154348A1