A scalp care composition with the effects of preventing dandruff shedding, controlling oil, relieving itching

Abstract

The present invention belongs to the technical field of washing and care products, and particularly relates to a scalp care composition having the effects of preventing hair loss, removing dandruff, controlling oil, and relieving itching, and a preparation method and use thereof. The composition comprises the following components: a natural plant extract composition, natural amino acids, hydroxyapatite, allantoin, sulfated glycopeptide, and water, wherein the natural plant extract composition comprises ginger root extract, angelica root extract, biota orientalis leaf extract, polygonum multiflorum root extract, notoginseng root extract, and lithospermum erythrorhizon root extract. Through the synergistic effect of the above components, the composition of the present invention significantly improves the moisture retention, repair function, and inhibitory effect on inflammatory factors of the scalp, and when applied to shampoo, can significantly reduce the irritation of the shampoo to the scalp. Therefore, the scalp care composition of the present invention has the composite effects of preventing hair loss, removing dandruff, controlling oil, and relieving itching, and the preparation method is simple and easy to industrialize.

Description

Technical Field

[0001] The present invention belongs to the technical field of hair care products, and particularly relates to a scalp care composition having the functions of preventing hair loss, removing dandruff, controlling oil, and relieving itching, a preparation method thereof, and uses thereof. Background Art

[0002] Hair has the functions of defense, protection, and enhancing information exchange and beauty. Hair is generated by hair follicles, which are complex skin appendages that continuously undergo a cyclic growth of growth phase, regression phase, and resting phase. Once the hair follicle cycle is disordered, it will affect the normal growth of hair follicles, leading to the occurrence of hair loss diseases. In addition, the health of the scalp is closely related to the health of the hair follicles and hair attached to it. However, the scalp is exposed to the environment every day, and many potential factors, such as ultraviolet rays, air pollutants, etc., may cause damage to the skin barrier by destroying the stratum corneum, resulting in inflammatory reactions or cell damage such as redness, itching, and stinging on the scalp.

[0003] The most common pathological hair loss is seborrheic alopecia, also known as androgenetic alopecia, which accounts for more than 95% of the incidence of pathological hair loss and is usually accompanied by the problem of excessive scalp sebum secretion. In recent years, with the intensification of social competition, increased survival pressure, high-fat diet, reduced sleep, environmental impact, and the use of hair styling products such as hair dyeing and perming, there has been a trend of younger age among hair loss patients, and the middle-aged and young people have become the main force of hair loss. Existing scalp care products for cleaning the scalp generally contain a large amount of ingredients such as surfactants, fragrances, and preservatives, which further exacerbate the damage of the scalp barrier.

[0004] Seemingly harmless hair loss often brings unimaginable mental and psychological burdens to patients. Such hair loss people usually have a very strong desire for care or treatment. Therefore, anti-hair loss and hair growth drugs and scalp care hair care products have attracted much attention. At present, the common hair growth agents on the Chinese market are mainly various hair growth shampoos and traditional Chinese medicine health products. The common hair growth shampoos on the market mainly reduce seborrheic alopecia by removing scalp oil, but obviously their effect is poor and there is a problem of treating the symptoms rather than the root cause. The traditional Chinese medicine health products for promoting hair growth mainly promote hair growth by improving microcirculation, but usually there are also problems such as poor effect and inconvenient use. Therefore, there is a huge market demand for scalp care products (especially shampoos) with strong composite functions of preventing hair loss, removing dandruff, controlling oil, and relieving itching, good consumer experience, and convenient use.

[0005] In view of the urgent needs in many aspects such as the hair care and growth effect and the composite functions that enable consumers to have a good use experience, it is very necessary to develop a scalp care composition that simultaneously has multiple composite functions such as preventing hair loss, removing dandruff, controlling oil, and relieving itching and has a good consumer experience. Summary of the Invention

[0006] In view of the deficiencies of the prior art, the present invention provides a scalp care composition with the effects of preventing hair loss, removing dandruff, controlling oil, relieving itching, and its preparation method and uses.

[0007] Specifically, the present invention is achieved through the following technical solutions in several aspects:

[0008] In the first aspect, the present invention provides a scalp care composition with the effects of preventing hair loss, removing dandruff, controlling oil, and relieving itching. Calculated by weight parts, the composition comprises the following components: 0.5 - 20 parts of a natural plant extract composition, 0.5 - 10 parts of natural amino acids, 0.5 - 3 parts of hydroxyapatite, 0.5 - 3 parts of allantoin, 0.5 - 3 parts of sulfated glycopeptide, and 0.5 - 20 parts of water.

[0009] As an optional way, in the above scalp care composition, calculated by weight parts, the composition comprises the following components: 5 - 15 parts of a natural plant extract composition, 1 - 8 parts of natural amino acids, 1 - 2 parts of hydroxyapatite, 1 - 2 parts of allantoin, 1 - 2 parts of sulfated glycopeptide, and 10 - 20 parts of water.

[0010] As an optional way, in the above scalp care composition, calculated by weight parts, the composition comprises the following components: 12 parts of a natural plant extract composition, 6 parts of natural amino acids, 1 part of hydroxyapatite, 2 parts of allantoin, 1 part of sulfated glycopeptide, and 18 parts of water.

[0011] As an optional way, in the above scalp care composition, the composition is made of a natural plant extract composition, natural amino acids, hydroxyapatite, allantoin, sulfated glycopeptide, and water.

[0012] As an optional way, in the above scalp care composition, the natural plant extract composition comprises one or more of the following: ZINGIBER OFFICINALE root extract, ANGELICA POLYMORPHASINENSIS root extract, BIOTA ORIENTALIS leaf extract, POLYGONUMMULTIFLORUM root extract, PANAX NOTOGINSENG root extract, and LITHOSPERMUMERYTHRORHIZON root extract.

[0013] As an optional way, in the above scalp care composition, the natural plant extract composition comprises: ZINGIBER OFFICINALE root extract, ANGELICA POLYMORPHASINENSIS root extract, BIOTA ORIENTALIS leaf extract, POLYGONUMMULTIFLORUM root extract, PANAX NOTOGINSENG root extract, and LITHOSPERMUMERYTHRORHIZON root extract.

[0014] As an alternative, in the above scalp care composition, the natural plant extract composition is made from the following components: ginger root extract, angelica root extract, oriental arborvitae leaf extract, fleeceflower root extract, notoginseng root extract, and purple gromwell root extract.

[0015] Preferably, by weight ratio, ginger root extract: angelica root extract: oriental arborvitae leaf extract: fleeceflower root extract: notoginseng root extract: purple gromwell root extract is 1:1:1:1:1:1.

[0016] As an alternative, in the above scalp care composition, the natural amino acids include one or more of the following: glycine, alanine, serine, valine, proline, threonine, isoleucine, phenylalanine, histidine, arginine, or aspartic acid.

[0017] Preferably, the natural amino acids are made from the following components: glycine, serine, valine, and arginine.

[0018] More preferably, by weight ratio, glycine: serine: valine: arginine is 2:2:1:1.

[0019] As an alternative, in the above scalp care composition, the sucro-glycopeptide is a glycopeptide substance, and the sucro-glycopeptide is obtained by sulfonating the glycopeptide extracted from the duodenum or gastric mucosa of pigs.

[0020] Preferably, the CAS number of the sucro-glycopeptide is 54182-59-1, and it can be directly purchased.

[0021] As an alternative, in the above scalp care composition, the hydroxyapatite is ultrafine hydroxyapatite powder.

[0022] Preferably, the average particle size of the ultrafine hydroxyapatite powder is 1-8 μm, more preferably, the average particle size is 3-6 μm, and most preferably, the average particle size is 3.5 μm.

[0023] In the second aspect, the present invention provides a preparation method of the scalp care composition described in the first aspect above, including the following steps: mixing each component evenly to obtain the scalp care composition.

[0024] Preferably, the preparation method includes the following steps: at room temperature, mix the natural plant extract composition and hydroxyapatite, add half of the water, stir while adding water, heat to 50 °C and stop heating, maintain this temperature, and continue stirring until evenly mixed. Under stirring conditions, cool the mixture to room temperature, then add natural amino acids, allantoin, and sucro-glycopeptide and the remaining water, and continue gently stirring at room temperature for 10 minutes to obtain the scalp care composition.

[0025] In a third aspect, the present invention provides the use of the scalp care composition described in the first aspect above in the preparation of scalp care hair care products.

[0026] As an alternative, in the above use, the scalp care hair care products are selected from: shampoo, hair shampoo, hair conditioner, essence, hair mask or scalp care liquid.

[0027] Preferably, the scalp care hair care product is shampoo or hair shampoo.

[0028] As an alternative, in the above use, by weight percentage, the scalp care hair care product contains 8%-20% of the scalp care composition described in the first aspect above.

[0029] Preferably, by weight percentage, the scalp care hair care product contains 8%-15% of the scalp care composition described in the first aspect above.

[0030] More preferably, by weight percentage, the scalp care hair care product contains 8%-10% of the scalp care composition described in the first aspect above.

[0031] In a fourth aspect, as a representative example, the present invention provides a hair shampoo which, by weight percentage, contains 8%-15% of the scalp care composition described in the first aspect above.

[0032] Preferably, by weight percentage, the hair shampoo contains 10% of the scalp care composition described in the first aspect above.

[0033] It should be understood that within the scope of the present invention, the above technical features of the present invention and the technical features specifically described below (such as in the examples) can be combined with each other to form new or preferred technical solutions. Due to space limitations, they will not be elaborated one by one here.

[0034] The present invention has the following beneficial effects compared with the prior art:

[0035] (1) Through the synergistic effect of each component, the scalp care composition of the present invention significantly improves the moisturizing property, repair function and inhibitory effect on inflammatory factors of the scalp, and when applied to hair shampoo, it can significantly reduce the irritation of the hair shampoo to the scalp.

[0036] (2) The scalp care composition of the present invention has the compound effects of preventing hair loss, removing dandruff, controlling oil and relieving itching, and the consumer experience is good.

[0037] (3) The raw materials of the scalp care composition of the present invention are widely sourced and can all be obtained by purchase. The active ingredients from natural sources are highly safe, non-irritating, and the preparation method is simple and easy to industrialize. Detailed implementation mode

[0038] For the convenience of those skilled in the art, the following describes various main active ingredients involved in the present invention.

[0039] "Hydroxyapatite (HAP)" is the main component of human bones and teeth, with good biocompatibility, non-toxic, non-irritating, no human rejection reaction, no aging, sensitization or carcinogenesis, and can chemically combine with bone tissue. Currently, it has been widely used as bone substitute materials, plastic and cosmetic surgery materials, dental materials, chromatography purification materials, calcium supplements, and hemostatic materials, etc. However, there is no report in the prior art on the use of hydroxyapatite ultrafine powder within a specific particle size range for scalp care.

[0040] "Allantoin" is a substance that softens the cutin layer of the skin, helps the dead skin cells to shed, helps the skin retain more moisture, and makes the skin smooth; allantoin can easily reach the deep layer of the skin, promoting fibroblasts to generate more collagen, elastin, and mucopolysaccharides, thus effectively reducing and preventing the formation of wrinkles. Allantoin can inhibit the generation of 1L-1α and has sedative, astringent, and anti-inflammatory effects. Allantoin can reduce the adhesion of cutin layer cells and accelerate the renewal of epidermal cells.

[0041] "Sulphated glycopeptide" is a sulfated polysaccharide ester obtained by sulfating glycopeptide extracted from the duodenum of pigs. It is a semi-synthetic glycopeptide polysulfate and belongs to mucopolysaccharides. It has various biological activities of mucopolysaccharides, such as anti-tumor, anti-virus, anti-atherosclerosis, anti-inflammatory, and lipid-lowering effects. The CAS number of sulphated glycopeptide is 54182-59-1, and it can be directly purchased.

[0042] "Ginger (ZINGIBER OFFICINALE) root extract" mainly functions as an antioxidant, anti-inflammatory agent, and skin conditioner in skin care products. It is relatively safe to use with confidence and generally has no impact on pregnant women. Ginger root extract has a certain inhibitory effect on dermatophytes, Candida albicans, and oral pathogens, but has poor inhibitory effects on common molds, etc.; it can enhance the activity of the skin, activate the skin, has antioxidant and anti-aging effects; it can also promote hair growth and act as a hair promoter; at the same time, it has moisturizing and odor-inhibiting effects.

[0043] The main role of "Angelica polymorpha sinensis root extract" in cosmetics and skin care products is as an antioxidant and skin conditioner. It is relatively safe and can be used without any worries. It generally has no effect on pregnant women. Based on the effect of angelica in promoting blood circulation and removing blood stasis and improving skin microcirculation, it can be used in many cosmetics that promote blood circulation, such as hair growth, regulating skin secretion, supplementing nutrition, and dissolving dark circles. The effect of angelica on the proliferation of vascular skin cells shows that it can solidify capillaries while promoting blood circulation. Angelica has good SOD-like activity, inhibiting membrane lipid peroxidation and free radical reactions caused by superoxide free radicals, and combining with biological membrane phospholipids to protect membrane lipids and other mechanisms to antagonize free radical damage to tissues. It has special effects on gray complexion or sores caused by free radical blockade. The activation rate of luciferase and the proliferation of stem cells show anti-aging effects.

[0044] The main function of "BiOTA ORIENTALIS leaf extract" in cosmetics and skin care products is to prevent hair loss and nourish hair. It is relatively safe and can be used with confidence. It generally has no effect on pregnant women. BiOTA ORIENTALIS leaf extract is a pure natural plant extract derived from the leaves of BiOTA ORIENTALIS. It can unclog the scalp so that nutrients are better absorbed by the hair roots, stimulate and care for the hair stems, prevent hair loss, and promote normal hair growth, achieving the effect of preventing hair loss and nourishing hair.

[0045] "Polygonum multiflorum root extract" is mainly used as an antibacterial agent, antioxidant, and moisturizer in cosmetics and skin care products. It is relatively safe and can be used with confidence. It generally has no effect on pregnant women. Polygonum multiflorum root extract is an extract of the dried root tubers of Polygonum multiflorum, a plant of the Polygonaceae family. The main functional ingredients are lecithin (good moisturizing effect), rhein, rhein, and other ingredients. Polygonum multiflorum is widely used as a cosmetic for oral or external use because of its ability to make hair black and shiny.

[0046] "PANAX NOTOGINSENG root extract" is mainly used as an anti-inflammatory agent, antioxidant and antibacterial agent in cosmetics and skin care products. Panax notoginseng extract inhibits edema and nuclear factor receptor activation, which is an indicator of anti-inflammatory ability. Panax notoginseng extract can be used as an anti-inflammatory agent; Panax notoginseng extract can eliminate oxygen free radicals, enhance the activity of endogenous superoxide dismutase, strengthen the body's ability to scavenge oxygen free radicals, reduce the chain reaction caused by oxygen free radicals, and reduce the peroxidation of lipids in the blood; Panax notoginseng extract has antibacterial properties, and Panax notoginseng total saponins have a strong inhibitory effect on certain fungi, and have a certain inhibitory effect on Staphylococcus aureus and Escherichia coli.

[0047] Lithospermum Erythrorhizon root extract is mainly used in cosmetics and skin care products for its antioxidant and anti-aging effects. It is relatively safe and can be used with confidence. It generally has no effect on pregnant women. Lithospermum root extract has the effect of promoting the activity of tissue proteases and has anti-fungal and anti-viral capabilities. It has a certain effect of enhancing the metabolism of skin cells, and combined with its antioxidant properties, it has an anti-aging effect.

[0048] The above-mentioned natural plant extracts and other raw materials from natural sources used in the scalp care composition with the functions of preventing dandruff, controlling oil and relieving itching of the present invention are all commercially available cosmetic raw materials that can be purchased.

[0049] The present invention will be further described with reference to specific embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the scope of the present invention.

[0050] If no specific techniques or conditions are specified in the examples, the techniques or conditions described in the literature in the field or the product instructions are used. If no manufacturer is specified for the reagents or instruments used, they are all conventional products that can be purchased through regular channels.

[0051] The experimental methods in the following examples are all conventional methods unless otherwise specified. The experimental materials used in the following examples are all commercially available products unless otherwise specified. Preparation Examples:

[0052] Example 1:

[0053] A scalp care composition with the effects of preventing dandruff, controlling oil and relieving itching, wherein the composition is prepared from the following components by weight: 12 parts of a natural plant extract composition, 6 parts of natural amino acids, 1 part of hydroxyapatite, 2 parts of allantoin, 1 part of thioglycopeptide and 18 parts of water; the natural plant extract composition is prepared from the following components: ginger root extract, angelica root extract, Platycladus orientalis leaf extract, Polygonum multiflorum root extract, Panax notoginseng root extract and Lithospermum officinale root extract, and the weight ratio of ginger root extract: angelica root extract: Platycladus orientalis leaf extract: Polygonum multiflorum root extract: Panax notoginseng root extract: Lithospermum officinale root extract is 1:1:1:1:1:1; the natural amino acids are prepared from the following components: glycine, serine, valine and arginine, and the weight ratio of glycine: serine: valine: arginine is 2:2:1:1; the hydroxyapatite is ultrafine hydroxyapatite powder with an average particle size of 3.5 μm.

[0054] The preparation method comprises the following steps: mixing the natural plant extract composition and hydroxyapatite at room temperature, adding half of the amount of water, stirring while adding the water, heating to 50°C and stopping heating, maintaining the temperature, and continuing stirring until the mixture is uniformly mixed. Under stirring conditions, the mixture is cooled to room temperature, and then natural amino acids, allantoin and sulglycopeptide and the remaining water are added, and the mixture is gently stirred for 10 minutes at room temperature to obtain the scalp care composition.

[0055] Example 2:

[0056] A scalp care composition with the effects of preventing dandruff, controlling oil and relieving itching, wherein the composition is prepared from the following components by weight: 10 parts of a natural plant extract composition, 8 parts of natural amino acids, 2 parts of hydroxyapatite, 1 part of allantoin, 1 part of thioglycopeptide and 18 parts of water; the natural plant extract composition is prepared from the following components: ginger root extract, angelica root extract, Platycladus orientalis leaf extract, Polygonum multiflorum root extract, Panax notoginseng root extract and Lithospermum officinale root extract, and the weight ratio of ginger root extract: angelica root extract: Platycladus orientalis leaf extract: Polygonum multiflorum root extract: Panax notoginseng root extract: Lithospermum officinale root extract is 1:1:1:1:1:1; the natural amino acids are prepared from the following components: glycine, serine, valine and arginine, and the weight ratio of glycine: serine: valine: arginine is 2:2:1:1; the hydroxyapatite is ultrafine hydroxyapatite powder with an average particle size of 4 μm.

[0057] The preparation method is the same as that in Example 1.

[0058] Example 3:

[0059] A scalp care composition with the effects of preventing dandruff, controlling oil and relieving itching, wherein the composition is prepared from the following components by weight: 8 parts of a natural plant extract composition, 8 parts of natural amino acids, 2 parts of hydroxyapatite, 2 parts of allantoin, 2 parts of thioglycopeptide and 18 parts of water; the natural plant extract composition is prepared from the following components: ginger root extract, angelica root extract, Platycladus orientalis leaf extract, Polygonum multiflorum root extract, Panax notoginseng root extract and Lithospermum officinale root extract, and the weight ratio of ginger root extract: angelica root extract: Platycladus orientalis leaf extract: Polygonum multiflorum root extract: Panax notoginseng root extract: Lithospermum officinale root extract is 1:1:1:1:1:1; the natural amino acids are prepared from the following components: glycine, serine, valine and arginine, and the weight ratio of glycine: serine: valine: arginine is 2:2:1:1; the hydroxyapatite is ultrafine hydroxyapatite powder with an average particle size of 3 μm.

[0060] The preparation method is the same as that in Example 1.

[0061] Comparative Example 1:

[0062] A scalp care composition, calculated on a weight basis, is made up of the following components: 12 parts of a natural plant extract composition, 6 parts of natural amino acids, 1 part of hydroxyapatite, 2 parts of allantoin, 1 part of sulfaglycopeptide, and 18 parts of water; the natural plant extract composition is made up of the following components: ginger root extract, angelica root extract, biota orientalis leaf extract, and polygonum multiflorum root extract. Calculated on a weight ratio basis, the ratio of ginger root extract:angelica root extract:biota orientalis leaf extract:polygonum multiflorum root extract is 2:2:1:1; the natural amino acids are made up of the following components: glycine, serine, valine, and arginine. Calculated on a weight ratio basis, the ratio of glycine:serine:valine:arginine is 2:2:1:1. The hydroxyapatite is hydroxyapatite ultrafine powder with an average particle size of 3.5 μm.

[0063] The preparation method is the same as that of Example 1.

[0064] Comparative Example 2:

[0065] A scalp care composition with the effects of preventing hair loss, removing dandruff, controlling oil, and relieving itching, calculated on a weight basis, is made up of the following components: 12 parts of a natural plant extract composition, 6 parts of natural amino acids, 1 part of hydroxyapatite, 2 parts of allantoin, 1 part of sulfaglycopeptide, and 18 parts of water; the natural plant extract composition is made up of the following components: ginger root extract, angelica root extract, biota orientalis leaf extract, polygonum multiflorum root extract, notoginseng root extract, and purple gromwell root extract. Calculated on a weight ratio basis, the ratio of ginger root extract:angelica root extract:biota orientalis leaf extract:polygonum multiflorum root extract:notoginseng root extract:purple gromwell root extract is 1:1:1:1:1:1; the natural amino acids are made up of glycine and serine. Calculated on a weight ratio basis, the ratio of glycine:serine is 1:1. The hydroxyapatite is hydroxyapatite ultrafine powder with an average particle size of 3.5 μm.

[0066] The preparation method is the same as that of Example 1.

[0067] Comparative Example 3:

[0068] A scalp care composition with the effects of preventing hair loss, removing dandruff, controlling oil, and relieving itching. By weight, the composition is made from the following components: 12 parts of natural plant extract composition, 6 parts of natural amino acids, 1 part of hydroxyapatite, 3 parts of allantoin, and 18 parts of water; the natural plant extract composition is made from the following components: ginger root extract, angelica root extract, biota orientalis leaf extract, polygonum multiflorum root extract, notoginseng root extract, and lithospermum erythrorhizon root extract. By weight ratio, ginger root extract: angelica root extract: biota orientalis leaf extract: polygonum multiflorum root extract: notoginseng root extract: lithospermum erythrorhizon root extract is 1:1:1:1:1:1; the natural amino acids are made from the following components: glycine, serine, valine, and arginine. By weight ratio, glycine: serine: valine: arginine is 2:2:1:1. The hydroxyapatite is ultrafine hydroxyapatite powder with an average particle size of 3.5 μm.

[0069] The preparation method is the same as that of Example 1.

[0070] Comparative Example 4:

[0071] A scalp care composition with the effects of preventing hair loss, removing dandruff, controlling oil, and relieving itching. By weight, the composition is made from the following components: 12 parts of natural plant extract composition, 6 parts of natural amino acids, 1 part of hydroxyapatite, 2 parts of allantoin, 1 part of sulfated glycoprotein, and 18 parts of water; the natural plant extract composition is made from the following components: ginger root extract, angelica root extract, biota orientalis leaf extract, polygonum multiflorum root extract, notoginseng root extract, and lithospermum erythrorhizon root extract. By weight ratio, ginger root extract: angelica root extract: biota orientalis leaf extract: polygonum multiflorum root extract: notoginseng root extract: lithospermum erythrorhizon root extract is 1:1:1:1:1:1; the natural amino acids are made from the following components: glycine, serine, valine, and arginine. By weight ratio, glycine: serine: valine: arginine is 2:2:1:1. The hydroxyapatite is ultrafine hydroxyapatite powder with an average particle size of 350 nm.

[0072] The preparation method is the same as that of Example 1.

[0073] Effect Examples:

[0074] Effect Example 1: Sensory evaluation test of foam experience and use comfort of shampoo containing the scalp care composition of the present invention Evaluation test

[0075] Using a conventional shampoo matrix, the compositions of Examples 1 - 3 and Comparative Examples 1 - 4 were made into 10% shampoos by weight percentage. Using people with the same hair quality as experimental subjects, with 20 people in each group, after each group of subjects used the shampoos prepared from the above Examples 1 - 3 and Comparative Examples 1 - 4 and the blank shampoo matrix respectively, a sensory evaluation of the foam experience degree was carried out based on the foaming power and foam texture, and a sensory evaluation was carried out based on the use comfort.

[0076] Specifically, the score of the sensory evaluation method is from 1 to 5 points. 1 point represents foam that is easy to break and loose, with weak foaming power, and 5 points represents foam that is soft, fine, and dense, with strong foaming power. The larger the score, the better the foam experience of the subjects. For the evaluation of the use comfort of shampoo, the score is also from 1 to 5 points. 1 point represents obvious irritation, and 5 points represents no irritation during use. The larger the score, the higher the use comfort of the subjects. After the subjects scored, the scores of each group of experimental objects were statistically analyzed, and the average value of each group of scores was calculated. The results are shown in Table 1 below.

[0077] Table 1: Sensory evaluation results of foam experience and use comfort of shampoo containing the scalp care composition of the present invention

[0078] Group Average score of foam sensory experience Use comfort Example 1 4.9 4.9 Example 2 4.9 4.8 Example 3 4.9 4.9 Comparative Example 1 4.8 4.8 Comparative Example 2 3.5 4.4 Comparative Example 3 3.2 4.1 Comparative Example 4 4.7 4.8 Blank matrix 3.1 3.5

[0079] As shown in Table 1, the experimental results show that the blank matrix is relatively poor both in terms of foam sensory experience and use comfort. The shampoos containing Examples 1-3 have better experience in foaming power and foam texture than Comparative Examples 1-4 and the blank matrix. From the experimental results of the shampoos containing Comparative Examples 1-4, it can be seen that the changes in the types of natural plant extracts and the particle size of hydroxyapatite in the composition have little effect on the foam experience and use comfort of the shampoo. However, whether the composition contains sulfated glycoprotein and the types of amino acids contained both have a greater impact on the foam experience and use comfort. Thus, it can be seen that the shampoo containing the scalp care composition of the present invention significantly improves the foam performance of the shampoo by containing sulfated glycoprotein and amino acids with specific compositions and dosage ratios, can effectively achieve thickening and produce foam with excellent properties. At the same time, the shampoo containing the scalp care composition of the present invention is non-irritating and has a high use comfort.

[0080] Effect Example 2: Oil control, dandruff removal, hair growth and hair care effect test of shampoo containing the scalp care composition of the present invention Test

[0081] Using a conventional shampoo matrix, the compositions of Example 1 and Comparative Examples 1-4 were made into 10% shampoos by weight. 120 volunteers with a lot of dandruff and oily hair were randomly selected, aged between 25 and 60 years. The volunteers had no diseases causing a large amount of hair loss, only the scalp was prone to itching and oiliness, the average daily hair loss was more than 100 strands, and the hair loss lasted for more than 2 months. The above volunteers were randomly divided into 6 groups, with 20 people in each group, and they used the shampoos prepared from the above Example 1 and Comparative Examples 1-4 and the blank shampoo matrix respectively, shampooing once every morning. After continuous shampooing for 30 days, the oiliness of the hair and the effect of dandruff were observed in the morning.

[0082] The sebum content of the testers' scalps was measured using a sebum meter Sebumeter SM815, and the data was recorded as D0. The product was used to wash hair once a day, and the sebum content was measured on the 20th and 30th days, and the data was recorded.

[0083] Rate of change of sebum content (%) = { (Sebum content after using the product - Sebum content before using the product) / Sebum content before using the product} × 100%

[0084] In addition, at the end of the study, the hair volume and hair density of the volunteers were observed and statistically analyzed.

[0085] Table 2: Test results of the oil control effect of the shampoo containing the scalp care composition of the present invention

[0086] Group Oil change rate in 20 days (%) Oil change rate in 30 days (%) Example 1 -23.4 -34.2 Comparative Example 1 -21.5 -33.8 Comparative Example 2 -22.9 -34.3 Comparative Example 3 -23.5 -33.9 Comparative Example 4 -18.7 -28.5 Blank matrix -6.1 -6.7

[0087] As shown in Table 2, the experimental results show that the main substance that plays an oil control role in the shampoo containing the scalp care composition of the present invention is ultrafine hydroxyapatite powder. However, after comparing the results of Example 1 group and Comparative Example 4 group, it is found that for the oil control effect, it is not that the lower the particle size of the ultrafine hydroxyapatite powder, the better. The oil control effect of nano-sized ultrafine hydroxyapatite powder is actually inferior to that of micron-sized.

[0088] In addition, during the experiment, the anti-dandruff effect of the shampoo containing the scalp care composition of the present invention was also observed. The results show that the Example 1 group has good oil control and anti-dandruff effects at the same time, and the total anti-dandruff effective rate can reach more than 98%. The anti-dandruff effects of Comparative Examples 1-4 groups decreased to varying degrees. Among them, the types of natural plant extracts and sulfated glycopeptides have a greater impact on the anti-dandruff effect. It can be seen that the shampoo containing the scalp care composition of the present invention has good oil control and anti-dandruff effects.

[0089] Table 3: Test results of the hair care and hair growth effects of the shampoo containing the scalp care composition of the present invention

[0090]

[0091] As shown in Table 3, the experimental results indicate that the shampoo containing the scalp care composition of the present invention (Example 1 group) has the best hair care and growth promoting effects. The proportions of significantly reduced hair loss and regrown hair in the bald areas among the volunteers in this group are as high as 97% and 93% respectively. It can also be seen from the above experimental results that both the types of natural plant extracts and sulfated glycoprotein in the scalp care composition of the present invention have a significant impact on hair care and growth promoting effects. When the types of natural plant extracts in the composition are changed and the sulfated glycoprotein component is deleted from the composition, the hair care and growth promoting effects of the composition are significantly reduced (see the experimental results of Comparative Example 1 group and Comparative Example 3 group respectively). It can be seen that in terms of hair care and growth promotion, the natural plant extracts and sulfated glycoprotein in the composition of the present invention play a synergistic effect.

[0092] Effect Example 3: Influence of the scalp care composition of the present invention on hair growth of mice

[0093] Male C57BL / 6J mice at 6 - 8 weeks of age were randomly divided into 4 groups, with 10 mice in each group. The first group was the blank control group, which only used water. The second to fourth groups used the compositions prepared in Example 1, Comparative Example 1, and Comparative Example 3 respectively. 24 hours after shaving the hair on the back of the mice (3×3 cm) in each group, the test substances were given once a day for 21 consecutive days. After the experiment ended, the experimental animals were euthanized, the length of the newly grown hair was measured, and hair follicle counting was performed on the test area. The statistical data are expressed as mean ± standard error. Statistical analysis was performed using repeated measures analysis of variance for comparison, and Fisher LSD test was used for comparison of differences between groups. The experimental data are shown in Table 4 below.

[0094] Table 4: Effects of the scalp care composition of the present invention on hair growth length and hair follicle number in mice (mean ± SE)

[0095] Group Hair length (mm) Number of hair follicles (pcs) Blank control group 8.22±0.19 78±2.46 Example 1 group <![CDATA[12.05±0.37 **，# > <![CDATA[118±3.94 **，# > Comparative Example 1 group <![CDATA[10.23±0.39 * > <![CDATA[102±3.15 * > Comparative Example 3 group 9.15±0.25 89±2.73

[0096] Note: *, p < 0.05, **, p < 0.01, compared with the blank group; #, p < 0.05, compared with the Comparative Example 3 group.

[0097] It can be seen from the experimental data in Table 4 that the compositions of the Example 1 group, Comparative Example 1 group, and Comparative Example 3 group can all increase the hair growth length and hair follicle number of mice to varying degrees. Among them, the hair length and hair follicle number of mice in the Example 1 group (p < 0.01) and Comparative Example 1 group (p < 0.05) are significantly higher than those of the blank control group. In addition, the hair length and hair follicle number of mice in the Example 1 group are also significantly higher than those of the Comparative Example 3 group (p < 0.05).

[0098] Consistent with the hair growth and hair care results in Effect Example 2, it can also be seen from the above experimental results that both the types of natural plant extracts and sulfated glycopeptides in the scalp care composition of the present invention have a significant impact on hair growth and hair care. When the types of natural plant extracts in the composition are changed and the sulfated glycopeptide component is deleted from the composition, the effects of the composition on promoting hair growth and increasing hair follicles decrease significantly. In contrast, whether the composition contains sulfated glycopeptides has a greater impact on the above effects of the composition.

[0099] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalent technologies, the present invention is also intended to include these changes and modifications.

Claims

1. A scalp care composition with the effects of preventing dandruff shedding, controlling oil, relieving itching, characterized in that: by weight, the composition is made of the following components: 12 parts of natural plant extract composition, 6 parts of natural amino acids, 1 part of hydroxyapatite, 2 parts of allantoin, 1 part of sulfated glycopeptide and 18 parts of water; the natural plant extract composition is made of the following components: ginger root extract, angelica root extract, biota orientalis leaf extract, polygonum multiflorum root extract, panax notoginseng root extract and lithospermum erythrorhizon root extract. By weight ratio, ginger root extract: angelica root extract: biota orientalis leaf extract: polygonum multiflorum root extract: panax notoginseng root extract: lithospermum erythrorhizon root extract is 1:1:1:1:1:1; the natural amino acids are made of the following components: glycine, serine, valine and arginine. By weight ratio, glycine: serine: valine: arginine is 2:2:1:1, and the hydroxyapatite is hydroxyapatite ultrafine powder with an average particle size of 3.5 μm.

2. The preparation method of the scalp care composition according to claim 1, characterized in that: comprises the following steps: at room temperature, mix the natural plant extract composition and hydroxyapatite, and add half of the amount of water. Stir while adding water, heat to 50 °C and stop heating. Keep this temperature and continue to stir until evenly mixed. Under stirring conditions, cool the mixture to room temperature, then add natural amino acids, allantoin and sulfated glycopeptide and the remaining water, and continue to gently stir at room temperature for 10 minutes to obtain the scalp care composition.

3. The application of the scalp care composition according to claim 1 in the preparation of scalp care washing and care products.

4. According to the application described in claim 3, characterized in that: the scalp care washing and care products are selected from: shampoo, conditioner, essence, hair mask or scalp care liquid.

5. According to the application described in claim 3, characterized in that: by weight percentage, the scalp care washing and care products contain 8%-20% of the scalp care composition described in claim 1.

6. A shampoo, characterized in that: by weight percentage, the shampoo contains 8%-15% of the scalp care composition described in claim 1.

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