A natural mineral multi-effect mouthwash and a method for preparing the same

Abstract

The application discloses a natural mineral multi-effect mouthwash, which comprises a platycodon grandiflorum extract, a scutellaria baicalensis extract, a honeysuckle extract, a mint extract, an eucalyptus extract, natural mine salt, volcanic lava mineral powder, pure water, sodium monofluorophosphate, camellia oil, xylitol, tea saponin, a dispersing agent and a surfactant. The natural mouthwash provided by the application can effectively remove pathogenic bacteria in the oral cavity by taking the platycodon grandiflorum extract, the scutellaria baicalensis extract, the honeysuckle extract, the mint extract and the eucalyptus extract as effective components, plays a role of protecting the oral cavity and treating oral diseases, and additionally adds the natural mine salt and the volcanic lava mineral powder, so that the effect of removing pathogenic bacteria can be enhanced and tooth enamel mineralization can be promoted. The mouthwash prepared by the application does not contain any harmful components and can be directly used for daily oral care.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of oral care and daily chemical products, in particular to a natural mineral multi-effect mouthwash and a preparation method thereof. BACKGROUND

[0002] Mouthwash, also known as oral rinse, mainly functions in cleaning the oral cavity, covering the halitosis caused by the decomposition of food residues by bacteria or yeast, and leaving a comfortable and refreshing feeling in the oral cavity.

[0003] With the improvement of people's living standards, oral hygiene and health are paid more and more attention by people, and people are no longer limited to twice a day of brushing teeth. For such a group of people, especially for those who go out, mouthwash that is convenient to carry has become a necessity and fashion. As an oral care product, the main function of mouthwash is to remove oral odor or assist in the treatment of common oral diseases.

[0004] Although there are some brands of mouthwash on the market, there are not many products that combine these two aspects to protect teeth and freshen breath. Since most mouthwashes mainly contain chemical substances that are irritating or harmful to the human body, they are not suitable for daily oral care.

[0005] Therefore, it is an urgent technical problem for those skilled in the art to provide a natural mineral multi-effect mouthwash that can remove oral odor and residues, has a therapeutic effect on oral diseases, and can promote enamel mineralization, and a preparation method thereof. SUMMARY

[0006] Therefore, the present application provides a natural mineral multi-effect mouthwash and a preparation method thereof.

[0007] In order to achieve the above-mentioned purpose, the present application adopts the following technical solutions:

[0008] A natural mineral multi-effect mouthwash, characterized in that it comprises the following raw materials in parts by weight: Platycodon grandiflorum extract 0.2-3 parts, Scutellaria baicalensis extract 0.5-5 parts, Honeysuckle extract 0.1-2 parts, Mint extract 0.3-3 parts, Eucalyptus extract 0.2-2 parts, natural mine salt 2-8 parts, volcanic lava mineral powder 1-5 parts, hydrolate 1-3 parts, sodium monofluorophosphate 2-5 parts, Camellia oil 5-15 parts, xylitol 1-5 parts, tea saponin 0.5-2 parts, dispersing agent 2-5 parts, and surfactant 2-5 parts.

[0009] Further, the hydrolate is any one of jasmine hydrolate, rose hydrolate and lavender hydrolate.

[0010] The beneficial effect of the further scheme is that the added hydrolat can make the mouthwash have different fragrance, and the hydrolat also has certain astringency, sterilization and anti-inflammatory effects, and can improve the effects of the mouthwash on removing oral bacteria and treating oral diseases.

[0011] Further, the dispersant is obtained by mixing sodium polyacrylate and ethylene glycol at a mass ratio of 1:1-2.

[0012] Further, the surfactant is sodium dodecyl benzene sulfonate.

[0013] The beneficial effect of the further scheme is that the natural mine salt and the volcanic lava mineral powder can be fully dispersed in the mouthwash by the dispersant and the surfactant, so that the effect of the mouthwash on promoting tooth axis mineralization can be improved.

[0014] The application also provides a preparation method of the natural mineral multi-effect mouthwash.

[0015] (1) The raw materials are weighed according to the above weight proportions;

[0016] (2) The natural mine salt and the volcanic lava mineral powder are mixed, crushed to 80-150 meshes, calcined at 800-1200℃ for 48-72h, and then crushed to 80-150 meshes again to obtain a mixed mineral salt.

[0017] (3) The extract of platycodon, the extract of scutellaria, the extract of honeysuckle, the extract of mint and the extract of eucalyptus are mixed and added with 50-100 times of water, and then heated and stirred uniformly in a water bath;

[0018] (4) The dispersant, the surfactant, sodium monofluorophosphate, camellia oil, xylitol and tea saponin are sequentially added to the extract mixture in step (3), and then heated and stirred uniformly in a water bath again;

[0019] (5) The mixed mineral salt and the hydrolat are added to the mixture in step (4), and then ultrasonic dispersion is performed after standing for 10-24h to obtain the natural mineral multi-effect mouthwash.

[0020] Further, the extract of platycodon is obtained by extracting platycodon in ethanol with a mass concentration of 50-70% for 12-24h, and then concentrated and freeze-dried;

[0021] The extract of scutellaria is obtained by extracting scutellaria in ethanol with a mass concentration of 10-60% for 12-24h, and then concentrated and freeze-dried;

[0022] The extract of honeysuckle is obtained by extracting honeysuckle in ethanol with a mass concentration of 10-60% for 12-24h, and then concentrated and freeze-dried;

[0023] The mint extract is extracted from mint in water for 12-24h, concentrated and freeze-dried to obtain;

[0024] The eucalyptus leaf extract is extracted from dark night in 70-95% ethanol by mass concentration for 12-24h, concentrated and freeze-dried to obtain.

[0025] Further, the water bath heating temperature in step (3) is 50-75℃, the stirring rate is 150-300r / min, and the heating and stirring time is 20-40min.

[0026] Further, the water bath heating temperature in step (4) is 50-75℃, the stirring rate is 150-300r / min, and the heating and stirring time is 20-40min.

[0027] Further, the ultrasonic power in step (5) is 120-180w, and the ultrasonic time is 10-20min.

[0028] The beneficial effect of the above further scheme is that the components in the calcined and modified natural mine salt and volcanic lava mineral powder are dissolved in the mouthwash, and the insoluble components are also successfully dispersed in the mouthwash, thereby improving the various effects of the mouthwash.

[0029] The beneficial effect of the present application is that the natural mouthwash provided by the present application uses the jiegeng extract, the huangqi extract, the jin yinhua extract, the mint extract and the eucalyptus leaf extract as effective components to effectively remove the pathogenic bacteria in the oral cavity, thereby playing a role in protecting the oral cavity and treating oral diseases. The additional addition of natural mine salt and volcanic lava mineral powder can not only enhance the effect of removing pathogenic bacteria but also promote the mineralization of dental enamel. The mouthwash prepared by the present application does not contain any harmful components and can be directly used for daily oral care. DETAILED DESCRIPTION

[0030] The technical solutions in the embodiments of the present application will be described below. Obviously, the described embodiments are only a part of the embodiments of the present application, not all. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of protection of the present application.

[0031] In the embodiments of the present application, the jiegeng extract is extracted from jiegeng in 60% ethanol by mass concentration for 18h, concentrated and freeze-dried to obtain;

[0032] The huangqi extract is extracted from huangqi in 30% ethanol by mass concentration for 18h, concentrated and freeze-dried to obtain;

[0033] The jin yinhua extract is extracted from jin yinhua in 30% ethanol by mass concentration for 18h, concentrated and freeze-dried to obtain;

[0034] The mint extract is obtained by extracting mint in water for 18h, concentrating and freeze-drying;

[0035] The eucalyptus leaf extract is obtained by extracting eucalyptus leaf in 85% ethanol by mass concentration for 18h, concentrating and freeze-drying.

[0036] Example 1

[0037] A natural mineral multi-effect mouthwash

[0038] (1) Take 3kg of platycodon grandiflorum extract, 0.5kg of scutellaria baicalensis extract, 2kg of honeysuckle extract, 0.3kg of mint extract, 2kg of eucalyptus leaf extract, 2kg of natural mineral salt, 5kg of volcanic lava mineral powder, 3kg of jasmine hydrolate, 2kg of sodium monofluorophosphate, 15kg of camellia oil, 1kg of xylitol, 0.5kg of tea saponin, 5kg of dispersant, and 2kg of sodium dodecylbenzenesulfonate. The dispersant is obtained by mixing sodium polyacrylate and ethylene glycol in a mass ratio of 1:2;

[0039] (2) Mix the natural mineral salt and the volcanic lava mineral powder, crush them to 80 mesh, then calcine them at 1200℃ for 48h, then crush them to 80 mesh again to obtain a mixed mineral salt. Reserve;

[0040] (3) Mix the platycodon grandiflorum extract, the scutellaria baicalensis extract, the honeysuckle extract, the mint extract, and the eucalyptus leaf extract, and add 100 times the amount of water, then heat in a water bath at 50℃ and stir at 300r / min for 40min;

[0041] (4) Add the dispersant, the sodium dodecylbenzenesulfonate, the sodium monofluorophosphate, the camellia oil, the xylitol, and the tea saponin to the extract mixture in step (3) in sequence, then heat in a water bath at 50℃ and stir at 300r / min for 40min again;

[0042] (5) Add the mixed mineral salt and the hydrolate to the mixture in step (4), first stand for 10h, then ultrasonically disperse for 20min at 120w to obtain a natural mineral multi-effect mouthwash.

[0043] Example 2

[0044] A natural mineral multi-effect mouthwash

[0045] (1) Take 0.2 kg of jiegeng extract, 5 kg of huangqi extract, 0.1 kg of jinyinhua extract, 3 kg of bohe extract, 0.2 kg of xueye extract, 8 kg of natural mine salt, 1 kg of volcanic lava mineral powder, 1 kg of lavender hydrolat, 5 kg of sodium monofluorophosphate, 5 kg of camellia oil, 5 kg of xylitol, 2 kg of teasaponin, 2 kg of dispersant, and 5 kg of sodium dodecylbenzenesulfonate, wherein the dispersant is obtained by mixing sodium polyacrylate and ethylene glycol at a mass ratio of 1:1;

[0046] (2) Mix the natural mine salt and the volcanic lava mineral powder, crush them to 150 mesh, then calcine them at 800°C for 72 h, then crush them to 150 mesh again to obtain a mixed mineral salt. Reserve;

[0047] (3) Mix the jiegeng extract, huangqi extract, jinyinhua extract, bohe extract, and xueye extract, and add 50 times the amount of water, then heat in a water bath at 75°C and stir at 150 r / min for 20 min;

[0048] (4) Add the dispersant, sodium dodecylbenzenesulfonate, sodium monofluorophosphate, camellia oil, xylitol, and teasaponin to the extract mixture in step (3) in sequence, then heat in a water bath at 75°C and stir at 150 r / min for 20 min again;

[0049] (5) Add the mixed mineral salt and the hydrolat to the mixture in step (4), stand for 24 h, then ultrasonically disperse at 180 w for 10 min to obtain a natural mineral multi-effect mouthwash.

[0050] Example 3

[0051] A natural mineral multi-effect mouthwash

[0052] (1) Take 0.2 kg of jiegeng extract, 5 kg of huangqi extract, 0.1 kg of jinyinhua extract, 3 kg of bohe extract, 0.2 kg of xueye extract, 8 kg of natural mine salt, 1 kg of volcanic lava mineral powder, 1 kg of lavender hydrolat, 5 kg of sodium monofluorophosphate, 5 kg of camellia oil, 5 kg of xylitol, 2 kg of teasaponin, 2 kg of dispersant, and 5 kg of sodium dodecylbenzenesulfonate, wherein the dispersant is obtained by mixing sodium polyacrylate and ethylene glycol at a mass ratio of 1:1;

[0053] (2) Mix the natural mine salt and the volcanic lava mineral powder, crush them to 120 mesh, then calcine them at 1000°C for 56 h, then crush them to 120 mesh again to obtain a mixed mineral salt. Reserve;

[0054] (3) Mix the jiegeng extract, huangqi extract, jinyinhua extract, bohe extract, and xueye extract, and add 75 times the amount of water, then heat in a water bath at 65°C and stir at 200 r / min for 30 min;

[0055] (4) Add dispersant, sodium dodecyl benzene sulfonate, sodium monofluorophosphate, camellia oil, xylitol and tea saponin into the extract mixture in step (3) in turn, and heat in water bath at 65 ℃ again for 30 min with stirring at 200 r / min;

[0056] (5) Add mixed mineral salt and hydrolat into the mixture in step (4), and stand for 18 h, then disperse with ultrasonic at 150 W for 15 min to obtain natural mineral multi-effect mouthwash.

[0057] Example 4

[0058] A natural mineral multi-effect mouthwash

[0059] (1) Take 0.7 kg of platycodon grandiflorum extract, 4.2 kg of scutellaria baicalensis extract, 0.5 kg of honeysuckle extract, 2.7 kg of mint extract, 1.5 kg of eucalyptus extract, 6 kg of natural mineral salt, 2 kg of volcanic lava mineral powder, 2 kg of jasmine hydrolat, 3 kg of sodium monofluorophosphate, 5 kg of camellia oil, 5 kg of xylitol, 0.5 kg of tea saponin, 2 kg of dispersant, and 4 kg of sodium dodecyl benzene sulfonate, wherein the dispersant is obtained by mixing sodium polyacrylate and ethylene glycol at a mass ratio of 1:1.2;

[0060] (2) Mix the natural mineral salt and the volcanic lava mineral powder, crush them to 120 mesh, then calcine them at 950 ℃ for 48 h, and then crush them to 120 mesh again to obtain mixed mineral salt. Reserve;

[0061] (3) Mix the platycodon grandiflorum extract, the scutellaria baicalensis extract, the honeysuckle extract, the mint extract and the eucalyptus extract, and add 80 times of water, then heat in water bath at 70 ℃ with stirring at 220 r / min for 35 min;

[0062] (4) Add dispersant, sodium dodecyl benzene sulfonate, sodium monofluorophosphate, camellia oil, xylitol and tea saponin into the extract mixture in step (3) in turn, and heat in water bath at 70 ℃ again for 35 min with stirring at 220 r / min;

[0063] (5) Add mixed mineral salt and hydrolat into the mixture in step (4), and stand for 12 h, then disperse with ultrasonic at 160 W for 18 min to obtain natural mineral multi-effect mouthwash.

[0064] Example 5

[0065] A natural mineral multi-effect mouthwash

[0066] (1) Take jiegeng extract 2.7 kg, Huangqi extract 2.8 kg, jinyinhua extract 1.4 kg, bohe extract 2.5 kg, e'xiao extract 0.4 kg, natural mine salt 3 kg, volcano lava mineral powder 3 kg, lavender hydrolat 3 kg, sodium monofluorophosphate 3 kg, camellia oil 7 kg, xylitol 4 kg, teasaponin 1.5 kg, dispersant 4 kg, sodium dodecyl benzene sulfonate 4 kg, and the dispersant is obtained by mixing sodium polyacrylate and ethylene glycol at a mass ratio of 1:1.8;

[0067] (2) Mix the natural mine salt and the volcano lava mineral powder, crush them to 150 mesh, then calcine them at 1150 DEG C for 50 h, then crush them to 150 mesh again to obtain the mixed mineral salt. Standby;

[0068] (3) Mix the jiegeng extract, Huangqi extract, jinyinhua extract, bohe extract and e'xiao extract, and add 95 times amount of water, then heat in water bath at 75 DEG C and stir at 180 r / min for 30 min;

[0069] (4) Add the dispersant, sodium dodecyl benzene sulfonate, sodium monofluorophosphate, camellia oil, xylitol and teasaponin into the extract mixture in step (3) in sequence, heat in water bath at 75 DEG C again and stir at 180 r / min for 30 min;

[0070] (5) Add the mixed mineral salt and the hydrolat into the mixture in step (4), stand for 10-24 h, then ultrasonically disperse at 160 W for 15 min to obtain the natural mineral multi-effect mouthwash.

[0071] Test example 1 toxicity test

[0072] Take 4-week-old Kunming mice as experimental objects, with an average weight of 22-28 g, and fast for 16 h before test, and drink water freely. The mouthwash prepared in example 5 is used, and according to the Hom method, 1000, 2150, 4640 and 10000 mg / kg body weight are set as four dose groups for male and female mice respectively, with 5 animals in each group, and the poisoning amount is calculated as 0.2 ml / 10 g body weight by using once oral gavage. No death is observed within two weeks, and it is determined as non-toxic level. The results are shown in table 1.

[0073] Table 1

[0074]

[0075]

[0076] The results in table 1 show that the mouthwash prepared in the application is a non-toxic level product.

[0077] Test example 2

[0078] According to the method in GB15797-2002 "Hygienic Standard for Disposable Sanitary Products", the suspension quantitative method is used to detect the bacteriostatic ability of the mouthwash on Staphylococcus aureus, Escherichia coli and Candida albicans, the detection concentration is 1:1, and the action time is 15 min, and the results are shown in Table 2.

[0079]

[0080] The results in Table 2 show that the mouthwash prepared in the application has excellent bactericidal and bacteriostatic ability.

[0081] Although the embodiments of the application have been shown and described above, it should be understood that the above embodiments are exemplary and are not to be construed as limiting the application, and those of ordinary skill in the art can make changes, modifications, replacements and variations to the above embodiments within the scope of the application.

Claims

1. A natural mineral mouthwash, characterized in that, The natural mineral water includes the following raw materials by weight: 0.2-3 parts of jiegeng extract, 0.5-5 parts of huangqin extract, 0.1-2 parts of jinyinhua extract, 0.3-3 parts of bohe extract, 0.2-2 parts of e'xiao extract, 2-8 parts of natural mine salt, 1-5 parts of volcano lava mineral powder, 1-3 parts of pure distillate, 2-5 parts of sodium monofluorophosphate, 5-15 parts of camellia oil, 1-5 parts of xylitol, 0.5-2 parts of teasaponin, 2-5 parts of dispersing agent, and 2-5 parts of surfactant; the dispersing agent is obtained by mixing sodium polyacrylate and ethylene glycol at a mass ratio of 1:1-2; and the surfactant is sodium dodecyl benzene sulfonate. The pure distillate is any one of jasmine pure distillate, rose pure distillate and lavender pure distillate.

2. A method of preparing a natural mineral mouthwash, characterized by, The method includes the following steps: (1) taking each raw material according to the weight parts in claim 1; (2) mixing the natural mine salt and the volcano lava mineral powder, crushing them to 80-150 mesh, calcining them at 800-1200℃ for 48-72h, and then crushing them to 80-150 mesh again to obtain the mixed mineral salt, which is ready for use; (3) mixing the jiegeng extract, huangqin extract, jinyinhua extract, bohe extract and e'xiao extract, adding 50-100 times of water, and then heating and stirring them uniformly in a water bath; (4) adding the dispersing agent, surfactant, sodium monofluorophosphate, camellia oil, xylitol and teasaponin into the extract mixture in step (3) in sequence, and then heating and stirring them uniformly in a water bath again; (5) adding the mixed mineral salt and pure distillate into the mixture in step (4), standing for 10-24h, and then ultrasonic dispersing to obtain the natural mineral water.

3. The method for preparing a natural mineral mouthwash according to claim 2, characterized in that, The jiegeng extract is obtained by extracting jiegeng in 50-70% ethanol for 12-24h, and then concentrating and freeze-drying; The huangqin extract is obtained by extracting huangqin in 10-60% ethanol for 12-24h, and then concentrating and freeze-drying; The jinyinhua extract is obtained by extracting jinyinhua in 10-60% ethanol for 12-24h, and then concentrating and freeze-drying; The bohe extract is obtained by extracting bohe in water for 12-24h, and then concentrating and freeze-drying; The e'xiao extract is obtained by extracting e'xiao in 70-95% ethanol for 12-24h, and then concentrating and freeze-drying.

4. The method for preparing a natural mineral mouthwash according to claim 2, characterized in that, The heating temperature in step (3) is 50-75℃, the stirring rate is 150-300r / min, and the heating and stirring time is 20-40min.

5. The method for preparing a natural mineral mouthwash according to claim 2, characterized in that, The heating temperature in step (4) is 50-75℃, the stirring rate is 150-300r / min, and the heating and stirring time is 20-40min.

6. The method for preparing a natural mineral mouthwash according to claim 2, characterized in that, The ultrasonic power in step (5) is 120-180w, and the ultrasonic time is 10-20min.

Images