Metabolic measurement device and method based on gas concentration and respiratory mechanics parameter fusion

Abstract

A metabolic measurement device and method based on gas concentration and respiratory mechanics parameter fusion, comprising a main control module, a gas concentration measurement module, a respiratory mechanics parameter measurement module, a metabolic parameter calculation module, and a gas concentration measurement and respiratory mechanics measurement integrated adapter; a sensing part of a respiratory mechanics sensor is arranged inside a hollow adapter main body; the metabolic parameter calculation module obtains real-time gas concentration from the gas concentration measurement module and obtains respiratory mechanics parameters from the respiratory mechanics parameter measurement module; and the metabolic parameter calculation module calculates metabolic parameters based on the gas concentration and the respiratory mechanics parameters. The measurement of gas concentration, respiratory mechanics parameters and metabolic parameters can be completed simultaneously, the measurement efficiency is improved, and the comprehensive cost of multi-parameter measurement is reduced. The metabolic parameters of a single breathing beat can be obtained, the respiratory mechanics parameters and the gas concentration are sampled at relatively close positions, the data synergy and consistency are higher, and the accuracy and consistency of metabolic synchronous calculation can be improved.

Description

Technical Field

[0001] This application relates to the medical field, and more particularly to a metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters. Background Technology

[0002] In clinical practice, a basal metabolic rate (BMR) meter is commonly used to measure oxygen consumption per unit time (O2L / h) as one of the parameters for assessing metabolic capacity. Under relatively constant basal conditions, with an oxygen calorific value of 19.3 kJ, the basal metabolic rate (BMR) can be calculated by substituting the values ​​into the following formula: BMR = O2L / h × 19.3 kJ ÷ S. For example, a 30-year-old male with a body surface area of ​​1.5 m²... 2 Under basal conditions, the oxygen consumption was measured to be 12 L / h. Therefore, its BMR = 12 L / h × 19.3 kJ ÷ 1.5 m2 = 154.4 kJ / hm2. Then, according to the normal BMR values ​​for other age groups in Table 9-3, calculate the percentage of BMR that exceeds (+) or falls short (-) to determine whether it is within the normal range (generally ±10%).

[0003] Existing metabolic parameter measurements are all indirectly calculated results and are usually estimates that represent a basic state. They cannot provide real-time output of metabolic parameters, so the application of metabolic parameters is mostly limited to daily life.

[0004] In critically ill patients, real-time monitoring of their metabolic status is also very important. However, it is difficult to achieve real-time monitoring with current technology, so metabolic-related parameters are not monitored in critically ill patients.

[0005] Medical respiratory carbon dioxide concentration is one of the key parameters in modern clinical surgery and intensive care. Similarly, the measurement of respiratory mechanics parameters is also one of the key parameters in intensive care, especially for intubated patients, where airway management is crucial for life support.

[0006] In the existing technology, the measurement of respiratory mechanics parameters, which is relied upon for airway management, falls into two categories. One is that the respiratory mechanics parameter measurement is integrated into the ventilator or anesthesia machine and serves as a reference parameter for the operation of the ventilator or anesthesia machine. The other is that the respiratory mechanics parameter measurement module is configured as a monitor to measure respiratory mechanics parameters.

[0007] Whether integrated into a ventilator or anesthesia machine, or configured as a standalone monitoring device, respiratory mechanics parameter measurement modules typically require a separate flow sensor to work in conjunction with the main respiratory pathway. This setup increases the cost of respiratory mechanics measurements, as the sensor must be configured separately. Furthermore, it lacks sufficient coordination and consistency between respiratory mechanics parameter measurements and gas concentration measurements, making it impossible to use the data collaboratively for subsequent synchronous calculations.

[0008] Furthermore, there is no existing technology that can measure metabolic parameters of a single respiratory beat in real time. Summary of the Invention

[0009] The technical solution of this application overcomes the shortcomings of the prior art in that the measurement of metabolic parameters is not real-time. It proposes a metabolic measurement device and method based on an integrated adapter for gas concentration measurement and respiratory mechanics measurement, which integrates gas concentration measurement and respiratory mechanics measurement. The respiratory mechanics sensor is integrated into the adapter for gas concentration measurement, which becomes an integrated adapter for gas concentration measurement and respiratory mechanics measurement. This enables the metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters to simultaneously measure gas concentration and respiratory mechanics parameters, and to calculate metabolic parameters based on gas concentration and respiratory mechanics parameters.

[0010] The technical solution to the above-mentioned technical problems is a metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters. It includes a main control module, a gas concentration measurement module, a respiratory mechanics parameter measurement module, a metabolic parameter calculation module, and an integrated adapter for gas concentration measurement and respiratory mechanics measurement. The main control module and the gas concentration measurement module are electrically connected; the main control module and the respiratory mechanics parameter measurement module are electrically connected; the main control module and the metabolic parameter calculation module are electrically connected. The integrated adapter for gas concentration measurement and respiratory mechanics measurement includes a main gas path inlet connection A, a main gas path outlet connection B, a respiratory mechanics sensor, and a hollow adapter body. A gas path sampling interface is used to connect to a gas measurement sampling tube. The main gas path inlet connection A and the main gas path outlet connection B are used to install the adapter body in the main respiratory gas path. The sensing part of the respiratory mechanics sensor is located inside the hollow adapter body and is used to measure the respiratory mechanics parameters in the main respiratory gas path. The metabolic parameter calculation module obtains the real-time gas concentration from the gas concentration measurement module; the metabolic parameter calculation module obtains the respiratory mechanics parameters from the respiratory mechanics parameter measurement module; and the metabolic parameter calculation module calculates the metabolic parameters based on the gas concentration and respiratory mechanics parameters.

[0011] The gas concentration measurement module includes any one or more of the following: a carbon dioxide concentration measurement module, an oxygen measurement module, and an anesthetic gas concentration measurement module.

[0012] The respiratory mechanics parameters include the gas flow rate, gas pressure, and gas temperature of the main airway; the respiratory mechanics parameter module includes a gas flow rate measurement module, a gas pressure measurement module, and a gas temperature measurement module.

[0013] The metabolic parameter calculation module calculates the real-time flow rate of a single gas as: real-time gas flow rate × real-time concentration value of the single gas.

[0014] The integrated adapter for gas concentration measurement and respiratory mechanics measurement is a bypass gas concentration measurement and respiratory mechanics measurement integrated adapter; a gas sampling interface is provided on the upper part of the adapter body, and the gas path sampling interface is used to connect with the gas measurement sampling tube; the gas sampling interface is located in the middle of the adapter body, and the respiratory mechanics sensor is located at the front end of the gas sampling interface, closer to the main gas path inlet connection end A.

[0015] The integrated adapter for gas concentration measurement and respiratory mechanics measurement is a mainstream integrated adapter for gas concentration measurement and respiratory mechanics measurement. The adapter body is equipped with a gas measurement optical path component. The gas measurement optical path component is used for the transmission of light waves for gas measurement. The gas measurement optical path component is located in the middle of the adapter body, and the respiratory mechanics sensor is located at the front end of the gas measurement optical path component, closer to the main gas inlet connection end A.

[0016] The respiratory mechanics sensor includes a flow sensor based on the principle of heat flow sensing. Its sensing part is a hollow flow sensor used to measure gas flow through airflow. The respiratory mechanics sensor is located on the side near the main airway inlet connection A; or the respiratory mechanics sensor is located on the side near the main airway outlet connection B.

[0017] The adapter body has an opening at the top for the respiratory mechanics sensor to be assembled into the adapter body; the adapter body has an opening at the top and an opening sealing device is provided above the opening.

[0018] Another technical solution to the above-mentioned technical problems is a metabolic measurement method based on the fusion of gas concentration and respiratory mechanics parameters, which obtains respiratory mechanics parameters including real-time gas flow rate; calculates the real-time flow rate of a single gas in the overall gas path based on the obtained real-time gas concentration value; and calculates the corresponding metabolic parameters based on the real-time flow rate of the single gas.

[0019] The metabolic parameter calculation module calculates the real-time flow rate of a single gas = real-time gas flow rate × real-time concentration of the single gas; based on the real-time flow rate of the single gas, it calculates the metabolic amount of the single gas in each respiratory beat.

[0020] Based on the above-mentioned metabolic measurement device that integrates gas concentration and respiratory mechanics parameters; the real-time flow rate of a single gas includes carbon dioxide gas flow rate, oxygen gas flow rate, and anesthetic gas flow rate; carbon dioxide gas flow rate = real-time gas flow rate × real-time carbon dioxide gas concentration value; oxygen gas flow rate = real-time gas flow rate × real-time oxygen gas concentration value; anesthetic gas flow rate = real-time gas flow rate × real-time anesthetic gas concentration value.

[0021] Compared with the prior art, the beneficial effect of this application is 1: gas concentration and respiratory mechanics parameters are integrated into a metabolic parameter measuring device, which not only greatly improves the efficiency of metabolic parameters, but also obtains the metabolic parameters corresponding to each respiratory beat.

[0022] Compared with existing technologies, the second beneficial effect of this application is that it can acquire multiple gas concentration parameters and multiple respiratory mechanics parameters at once, and can also acquire gas concentration data, respiratory mechanics parameter data and metabolic parameter data very synchronously, providing a foundation for subsequent fusion calculations. For critically ill patients, especially intubated critically ill patients, metabolic parameters can be assessed according to respiratory rhythm, providing another physiological parameter reference for assessing their sudden condition.

[0023] Compared with the prior art, the beneficial effect of this application is 3: the integrated adapter for gas concentration measurement and respiratory mechanics measurement can simultaneously measure gas concentration and respiratory mechanics parameters without the need for a separate support component for the respiratory mechanics sensing component. It can collaboratively measure gas concentration, respiratory mechanics parameters and metabolic parameters, improving measurement efficiency and reducing the overall cost of acquiring multiple parameters. One component can complete the measurement of multiple parameters.

[0024] Compared with the prior art, the beneficial effect of this application is 4: the integrated adapter for gas concentration measurement and respiratory mechanics measurement can sample respiratory mechanics parameters and gas concentration at relatively close locations, thus the data coordination and consistency are higher, which facilitates subsequent synchronous calculation and improves the accuracy and consistency of synchronous calculation.

[0025] Compared with existing technologies, the beneficial effect of this application is 5: The integrated adapter for gas concentration measurement and respiratory mechanics measurement includes both a bypass gas concentration measurement and respiratory mechanics measurement integrated adapter and a mainstream gas concentration measurement and respiratory mechanics measurement integrated adapter. Regardless of the measurement method, it can simultaneously measure gas concentration and respiratory mechanics, and has good adaptability to measurement application scenarios. Regardless of the measurement method, it can simultaneously acquire three sets of measurement parameters, namely gas concentration parameters, respiratory mechanics parameters, and metabolic parameters.

[0026] Compared with the prior art, the beneficial effect of this application is 6: the respiratory mechanics sensor is set at the front end of the gas measurement optical path assembly, which is closer to the main air path inlet connection end A, and can reduce the influence of the flow disturbance caused by the airflow passing through the adapter on the respiratory mechanics measurement parameters.

[0027] Compared with the prior art, the beneficial effect of this application is 7: the respiratory mechanics sensor is set near the main airway inlet connection A, and / or the respiratory mechanics sensor is set near the main airway outlet connection B; multiple respiratory mechanics sensors can be flexibly integrated, which facilitates more refined detection of respiratory mechanics parameters and reduces airflow disturbance caused by the adapter.

[0028] Compared with the prior art, the beneficial effect of this application is 8: the flow sensor based on the heat flow sensing principle can accurately measure the flow rate and obtain temperature-related parameters for subsequent calculations.

[0029] Attached Figure

[0030] Figure 1 This is a schematic block diagram of a metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters;

[0031] Figure 2 This is a schematic block diagram of a metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters;

[0032] Figure 3 This is a schematic block diagram of a metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters;

[0033] Figure 4 This is a schematic block diagram of a metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters;

[0034] Figure 5 This is a schematic block diagram of a metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters;

[0035] Figure 6 This is a schematic diagram of an application scenario for a metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters, which includes an integrated adapter for mainstream gas concentration measurement and respiratory mechanics measurement. In the diagram, 600 is the mainstream adapter, and 500 is the metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters that works with the mainstream adapter.

[0036] Figure 7 This is a schematic diagram of an application scenario for a metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters, which includes an integrated adapter for bypass gas concentration measurement and respiratory mechanics measurement.

[0037] Figure 8 This is a perspective view of the combined state of a mainstream gas concentration measurement and respiratory mechanics measurement integrated adapter.

[0038] Figure 9 This is a cross-sectional schematic diagram of the integrated adapter for mainstream gas concentration measurement and respiratory mechanics measurement.

[0039] Figure 10 This is a schematic diagram of a respiratory mechanics sensor;

[0040] Figure 11 This is a schematic diagram of the disassembled state of the integrated adapter for bypass gas concentration measurement and respiratory mechanics measurement.

[0041] Figure 12 This is a perspective view of the combined state of the adapter for bypass gas concentration measurement and respiratory mechanics measurement;

[0042] Figure 13 This is a cross-sectional schematic diagram of the integrated adapter for mainstream gas concentration measurement and respiratory mechanics measurement.

[0043] Figure 14 This is a schematic diagram of various respiratory gas concentration parameters obtained from gas concentration measurements;

[0044] Figure 15 This is a schematic diagram of the flow waveforms of various respiratory gases. Detailed Implementation

[0045] The contents of this application will be further described in detail below with reference to various embodiments.

[0046] like Figure 1 In one embodiment of a metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters, the device includes a main control module, a gas concentration measurement module, a respiratory mechanics parameter measurement module, a metabolic parameter calculation module, and an integrated adapter for gas concentration measurement and respiratory mechanics measurement. The main control module and the gas concentration measurement module are electrically connected; the main control module and the respiratory mechanics parameter measurement module are electrically connected; the main control module and the metabolic parameter calculation module are electrically connected. The integrated adapter for gas concentration measurement and respiratory mechanics measurement includes a main gas path inlet connection A, a main gas path outlet connection B, a respiratory mechanics sensor, and a hollow adapter body. A gas path sampling interface is used to connect to a gas measurement sampling tube. The main gas path inlet connection A and the main gas path outlet connection B are used to install the adapter body in the main respiratory gas path. The sensing part of the respiratory mechanics sensor is disposed inside the hollow adapter body and is used to measure the respiratory mechanics parameters in the main respiratory gas path. The metabolic parameter calculation module obtains the real-time gas concentration from the gas concentration measurement module; the metabolic parameter calculation module obtains the respiratory mechanics parameters from the respiratory mechanics parameter measurement module; and the metabolic parameter calculation module calculates the metabolic parameters based on the gas concentration and respiratory mechanics parameters.

[0047] like Figure 2 In one embodiment of a metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters, the gas concentration measurement module includes any one or more of a carbon dioxide concentration measurement module, an oxygen measurement module, and an anesthetic gas concentration measurement module.

[0048] like Figure 3 In one embodiment of a metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters, the respiratory mechanics parameters include gas flow rate, gas pressure, and gas temperature in the main gas path. Accordingly, the respiratory mechanics parameter module includes a gas flow rate measurement module, a gas pressure measurement module, and a gas temperature measurement module.

[0049] The metabolic parameter calculation module calculates the real-time flow rate of a single gas as: real-time gas flow rate × real-time concentration value of the single gas.

[0050] like Figure 4 The integrated adapter for gas concentration measurement and respiratory mechanics measurement is a bypass gas concentration measurement and respiratory mechanics measurement integrated adapter; a gas sampling interface is provided on the upper part of the adapter body, and the gas sampling interface is used to connect with the gas measurement sampling tube; the gas sampling interface is located in the middle of the adapter body, and the respiratory mechanics sensor is located at the front end of the gas sampling interface, closer to the main gas inlet connection end A.

[0051] like Figure 5 The integrated adapter for gas concentration measurement and respiratory mechanics measurement is a mainstream integrated adapter for gas concentration measurement and respiratory mechanics measurement. The adapter body is equipped with a gas measurement optical path component. The gas measurement optical path component is used for the penetration of light waves for gas measurement. The gas measurement optical path component is located in the middle of the adapter body, and the respiratory mechanics sensor is located at the front end of the gas measurement optical path component, closer to the main gas inlet connection end A.

[0052] The adapter body has an opening at the top for the respiratory mechanics sensor to be assembled into the adapter body; the adapter body has an opening at the top and an opening sealing device is provided above the opening.

[0053] like Figures 8 to 13 The respiratory mechanics sensor includes a flow sensor 300 based on the principle of heat flow sensing, whose sensing part 310 is a hollow flow sensor used to measure gas flow through airflow; the respiratory mechanics sensor is located on the side near the main airway inlet connection A; or the respiratory mechanics sensor is located on the side near the main airway outlet connection B.

[0054] like Figure 11 and Figure 12 An opening 220 is provided on the upper part of the adapter body for the respiratory mechanics sensor 300 to be assembled into the interior of the adapter body 210; in some embodiments not shown in the accompanying drawings, an opening sealing device is provided above the opening.

[0055] like Figures 8 to 10 In an embodiment of the mainstream gas concentration measurement and respiratory mechanics measurement integrated adapter 100, a gas measurement optical path assembly 130 is provided on the adapter body 110; the gas measurement optical path assembly is used for the transmission of light waves for gas measurement. The gas measurement optical path assembly 130 is located in the middle of the adapter body 110, and the respiratory mechanics sensor 300 is located at the front end of the gas measurement optical path assembly, closer to the main gas path inlet connection end A111.

[0056] like Figures 8 to 10In the illustrated embodiment, the sensor interface 320 is disposed inside the hollow adapter body 110 for wireless connection with an external measurement module. It is used to independently output respiratory mechanics parameters.

[0057] like Figures 11 to 13 In one embodiment of an integrated adapter for gas concentration measurement and respiratory mechanics measurement, a bypass-type integrated adapter 200 for gas concentration measurement and respiratory mechanics measurement is provided on the upper part of the adapter body 210. The gas sampling interface 230 is used to connect to a gas measurement sampling tube. The gas measurement sampling tube is as follows: Figure 7 As indicated by the number 900. Figure 7 The reference numeral 800 is the gas sampling tube 900 and the gas circuit connection interface of the main unit, such as a monitor or anesthesia machine. The gas sampling interface 230 is located in the middle of the adapter body 210, and the respiratory mechanics sensor 300 is located at the front end of the gas sampling interface 230, closer to the main gas inlet connection terminal A211. This avoids the influence of bypass gas sampling on respiratory mechanics parameter measurements, enhancing the accuracy of respiratory mechanics measurements.

[0058] like Figures 10 to 13 In one embodiment of the integrated adapter for gas concentration measurement and respiratory mechanics measurement, a sensor interface 320 is further included. The sensor interface 320 is electrically connected to the sensing part 310 of the respiratory mechanics sensor 300. The sensor interface 320 is disposed outside the hollow adapter body 210 and is used for wired or wireless connection with an external measurement module. The sensor interface 320 and the sensing part 310 can be integrally formed as the respiratory mechanics sensor 300. The sensor interface 320 can also be a separate component, not integrated with the sensing part 310. In other embodiments, the sensor interface 320 is disposed inside the hollow adapter body 210 and is used for wireless connection with an external measurement module. It is used to output respiratory mechanics parameters independently. When the sensor interface 320 is disposed inside the hollow adapter body 210, it can also be part of the adapter measurement control module; the adapter measurement control module can be integrated with the adapter. The sensor interface 320 can also be separate from the adapter.

[0059] like Figures 8 to 13 The respiratory mechanics sensor 300 is positioned near the main airway inlet connection A. In some embodiments not shown in the accompanying drawings, the respiratory mechanics sensor is positioned near the main airway outlet connection B. It is used to detect airflow disturbances during gas sampling. In some embodiments not shown, a respiratory mechanics sensor is positioned at each of the two ends, near the main airway inlet connection A and near the main airway outlet connection B, to measure respiratory mechanics parameters at two points, obtaining more refined airflow disturbance information for subsequent synchronous calculations.

[0060] like Figure 13 In one embodiment, the upper part of the adapter body 210 is provided with an opening 220 for the respiratory mechanics sensor 300 to be assembled into the adapter body 210; in some embodiments not shown in the figures, an opening sealing device is provided above the opening 220. In other embodiments, the respiratory mechanics sensor 300 is equipped with a built-in sealing device to ensure the airtightness of the airway adapter.

[0061] In embodiments not shown in the accompanying drawings, the respiratory mechanics sensor includes a flow sensor based on the principle of heat flow sensing, wherein the sensing element is a hollow structure flow sensor used to measure gas flow through airflow. The respiratory mechanics sensor can also be other forms of flow sensors in the prior art or other different types of pressure sensors, temperature sensors, etc.

[0062] In embodiments not shown in the accompanying drawings, a metabolic measurement method based on the fusion of gas concentration and respiratory mechanics parameters is provided. This method acquires respiratory mechanics parameters, including real-time airway flow rate; calculates the real-time flow rate of a single gas in the overall airway based on the acquired real-time gas concentration value; and calculates corresponding metabolic parameters based on the real-time flow rate of the single gas. The metabolic parameter calculation module calculates the real-time flow rate of a single gas as real-time airway flow rate × real-time single gas concentration value; and calculates the metabolic amount of a single gas in each respiratory cycle based on the real-time flow rate of the single gas. Based on the aforementioned metabolic measurement device based on the fusion of gas concentration and respiratory mechanics parameters, the real-time flow rate of a single gas includes carbon dioxide gas flow rate, oxygen gas flow rate, and anesthetic gas flow rate; wherein carbon dioxide gas flow rate = real-time airway flow rate × real-time carbon dioxide gas concentration value; oxygen gas flow rate = real-time airway flow rate × real-time oxygen gas concentration value; and anesthetic gas flow rate = real-time airway flow rate × real-time anesthetic gas concentration value. Integrating over time yields the aforementioned gas metabolic amounts for the expiratory and inspiratory phases. Furthermore, the metabolic amounts for multiple time periods, such as per minute and per hour, can be calculated, providing objective quantitative parameters for various gas metabolisms.

[0063] like Figure 14 As shown in the figure, the waveforms of respiratory gas concentrations and real-time airway flow rates for three different gases are displayed. The four different gases are carbon dioxide (CO2), oxygen (O2), and the anesthetic gas desflurane (DES). Figure 15 As shown in the figure, the real-time flow rate and airway flow waveforms for three different respiratory gas concentrations are displayed. Based on the real-time gas concentration waveforms at each respiratory beat, the corresponding respiratory mechanics and metabolic parameters for each respiratory beat can be calculated, allowing for real-time assessment of metabolic parameters according to the respiratory beat; this provides richer metabolic parameter data for critical clinical monitoring.

[0064] This metabolic measurement device, based on the fusion of gas concentration and respiratory mechanics parameters, includes a main control module, a gas concentration measurement module, a respiratory mechanics parameter measurement module, a metabolic parameter calculation module, and an integrated adapter for gas concentration and respiratory mechanics measurements. The sensing element of the respiratory mechanics sensor is housed within the hollow adapter body. The metabolic parameter calculation module acquires real-time gas concentration from the gas concentration measurement module and respiratory mechanics parameters from the respiratory mechanics parameter measurement module. The metabolic parameter calculation module calculates metabolic parameters based on the gas concentration and respiratory mechanics parameters. It can simultaneously measure gas concentration, respiratory mechanics parameters, and metabolic parameters, improving measurement efficiency and reducing the overall cost of multi-parameter measurements. It can obtain metabolic parameters for a single respiratory cycle, and by sampling respiratory mechanics parameters and gas concentration at relatively close locations, data synergy and consistency are higher, improving the accuracy and consistency of synchronous metabolic calculations.

[0065] The above description is merely an embodiment of this application and does not limit the patent scope of this application. Any equivalent structural or procedural transformations made using the content of the application specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this application.

Claims

1. A metabolic measurement device based on gas concentration and respiratory mechanics parameter fusion, characterized in that, It comprises a main control module, a gas concentration measurement module, a respiratory mechanics parameter measurement module, a metabolic parameter calculation module, and a gas concentration measurement and respiratory mechanics measurement integrated adapter; The main control module and the gas concentration measurement module are electrically connected; The main control module and the respiratory mechanics parameter measurement module are electrically connected; The main control module and the metabolic parameter calculation module are electrically connected; The gas concentration measurement and respiratory mechanics measurement integrated adapter comprises a main gas path air inlet connection end A, a main gas path air outlet connection end B, a respiratory mechanics sensor, and a hollow adapter main body; The gas path sampling interface is used to connect with the gas measurement sampling tube; The main gas path air inlet connection end A and the main gas path air outlet connection end B are used to install the adapter main body in the main respiratory gas path; The sensing part of the respiratory mechanics sensor is arranged inside the hollow adapter main body and is used to measure the respiratory mechanics parameters in the main respiratory gas path; The metabolic parameter calculation module obtains real-time gas concentration from the gas concentration measurement module; The metabolic parameter calculation module obtains respiratory mechanics parameters from the respiratory mechanics parameter measurement module; The metabolic parameter calculation module obtains metabolic parameters based on gas concentration and respiratory mechanics parameters; The upper part of the adapter main body is provided with an opening for the respiratory mechanics sensor to be assembled into the adapter main body; An opening sealing device is arranged above the opening; The respiratory mechanics sensor comprises a flow sensor based on heat flow sensing principle, and the sensing part of the flow sensor is a hollow structure for measuring gas flow by airflow passing through; The respiratory mechanics sensor is arranged on the side close to the main gas path air inlet connection end A; Or the respiratory mechanics sensor is arranged on the side close to the main gas path air outlet connection end B.

2. The metabolic measurement device based on gas concentration and respiratory mechanics parameter fusion according to claim 1, characterized in that, The gas concentration measurement module comprises any one or more of a carbon dioxide concentration measurement module, an oxygen measurement module, and an anesthetic gas concentration measurement module.

3. The metabolic measurement device based on gas concentration and respiratory mechanics parameter fusion according to claim 1, characterized in that, The respiratory mechanics parameters include gas flow, gas pressure, and gas temperature of the main gas path; and the respiratory mechanics parameter module comprises a gas flow measurement module, a gas pressure measurement module, and a gas temperature measurement module; The metabolic parameter calculation module calculates the real-time flow of a single gas = real-time gas path flow × real-time single gas concentration value.

4. The metabolic measurement device based on gas concentration and respiratory mechanics parameter fusion according to claim 1, characterized in that, The gas concentration measurement and respiratory mechanics measurement integrated adapter is a side-stream gas concentration measurement and respiratory mechanics measurement integrated adapter; The upper part of the adapter main body is provided with a gas sampling interface, and the gas path sampling interface is used to connect with the gas measurement sampling tube; the gas sampling interface is arranged in the middle part of the adapter main body, and the respiratory mechanics sensor is arranged at the front end of the gas sampling interface, which is closer to the main gas path air inlet connection end A.

5. The metabolic measurement device based on gas concentration and respiratory mechanics parameter fusion according to claim 1, characterized in that, The gas concentration measurement and respiratory mechanics measurement integrated adapter is a mainstream gas concentration measurement and respiratory mechanics measurement integrated adapter, and a gas measurement light path assembly is arranged on the adapter body; the gas measurement light path assembly is used for gas measurement light wave penetration; the gas measurement light path assembly is arranged at the middle part of the adapter body, and the respiratory mechanics sensor is arranged at the front end of the gas measurement light path assembly and is closer to the main gas path air inlet connection end A.

6. A metabolic measurement method based on gas concentration and respiratory mechanics parameter fusion, characterized in that, The metabolic measurement device based on gas concentration and respiratory mechanics parameter fusion according to claim 1; The respiratory mechanics parameters include real-time gas path flow; according to the obtained real-time gas concentration value, the real-time flow of a single gas in the whole gas path is calculated; and the calculation of the corresponding material metabolism parameters is performed according to the real-time flow of the single gas; The metabolic parameter calculation module calculates the real-time flow of a single gas = real-time gas path flow x real-time single gas concentration value; and according to the real-time flow of the single gas, the metabolic amount of the single gas in each breathing beat is calculated; According to the real-time gas concentration waveform in each breathing beat, the respiratory mechanics parameters and the metabolic parameters corresponding to each breathing beat are calculated; Time integration can obtain the above-mentioned gas metabolic amount in the exhalation phase and the inhalation phase, and the metabolic amount in multiple time periods can be calculated.

7. The metabolic measurement method based on gas concentration and respiratory mechanics parameter fusion according to claim 6, characterized in that, The real-time flow of a single gas includes carbon dioxide gas flow, oxygen gas flow and anesthetic gas flow; The carbon dioxide gas flow = real-time gas path flow x real-time carbon dioxide gas concentration value; The oxygen gas flow = real-time gas path flow x real-time oxygen gas concentration value; The anesthetic gas flow = real-time gas path flow x real-time anesthetic gas concentration value.

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