A tissue printer

Abstract

The present application relates to a tissue slide printer, which relates to the technical field of medical equipment and includes a housing, a storage rack, a conveying mechanism, a printing device, a printing device, and a heating element. The housing is provided with a storage area, a printing area, a printing area, and a baking area. The storage rack is located in the storage area and is used to store and place glass slides. The conveying mechanism is located in the housing and is used to transport glass slides from the storage rack between the storage area, the printing area, the printing area, and the baking area. The printing device is located in the printing area and is used to print patient information. The printing device is located in the printing area and is used to apply tissue samples to glass slides and cover them with coverslips. The heating element is located in the baking area and is used to heat the glass slides coated with tissue samples. This can significantly improve the efficiency of tissue slide printing, effectively reduce the workload of staff, and alleviate the labor intensity of staff.

Description

Technical Field

[0001] The present application relates to the technical field of medical equipment, and in particular to a tissue printer. Background Art

[0002] Tissue prints are widely used in a variety of medical diagnostic fields, including molecular genetics and pathology, and have great potential for application in microscopic biopsies. In related technologies, tissue prints are performed by manual squeezing and smearing. The specific steps are as follows: Medical personnel first use tweezers to remove biopsy tissue soaked in saline and place it on a clean glass slide. A second clean glass slide is then placed over the biopsy tissue, pressing the two slides together to release cells, forming a tissue print specimen. The cells are then fixed with an electric heat treatment to produce a slide. The number of slides produced depends on the number and size of the specimens collected and the nature of the experiment.

[0003] The manual squeezing and smearing method for tissue printing has the following defects: manual preparation is greatly affected by human factors, and it is impossible to ensure that each slide is evenly stressed during squeezing and smearing, resulting in inconsistent cell dispersion and dispersion areas on the prepared slides. Before use, the entire slide must be manually scanned under an optical microscope to find the appropriate area and mark it before use.

[0004] To solve the above technical problems, a related art uses a printing device to compress biopsy tissue. The printing device includes a device body, a pressure sensor, and a movable plate. A cavity with an upper opening is provided in the device body. The pressure sensor is fixed to the bottom of the cavity. The movable plate is slidably arranged in the cavity. A handle is provided on the movable plate. When compressing the biopsy tissue, the biopsy tissue is placed between two glass slides. The lower glass slide is placed on the pressure sensor, and the movable plate is placed on the upper glass slide. The movable plate is manually pressed using the handle to squeeze the two glass slides. Although the above-mentioned printing device can improve the force uniformity of the glass slides to a certain extent, most of the operations in the tissue printing process need to be completed manually, and the operation convenience is poor. This increases the labor intensity of medical staff to a certain extent and reduces work efficiency. Summary of the Invention

[0005] The purpose of this application is to provide a tissue printer to solve the problems in the related art of poor operation convenience of the printing device, high labor intensity for medical staff and low work efficiency.

[0006] The present application provides a tissue printer that adopts the following technical solution:

[0007] A tissue printer comprises a housing, a storage rack, a conveying mechanism, a printing device, a film printing device and a heating element. The housing is provided with a storage area, a printing area, a film printing area and a film baking area.

[0008] The storage rack is provided at the storage area, and is used for storing and placing slides;

[0009] The conveying mechanism is arranged in the housing, and is used to transfer the slides from the storage rack between the storage area, the printing area, the printing area and the baking area;

[0010] The printing device is provided at the printing area, and the printing device is used to print patient information;

[0011] The printing device is provided at the printing area, and is used to apply the tissue sample on a glass slide and cover it with a cover glass;

[0012] The heating element is arranged in the baking area, and is used to heat the glass slide coated with the tissue sample.

[0013] By adopting the above technical solution, when tissue printing is required, the glass slide is moved from the storage area to the printing area through the conveying mechanism, the patient information label is printed by the printing device, and then the glass slide is moved to the printing area through the conveying mechanism, tissue cells are smeared on the glass slide through the printing device, and then the glass slide is moved to the baking area through the conveying mechanism to bake the tissue cells, thereby improving the operating efficiency of tissue printing and reducing the labor intensity of the staff.

[0014] Optionally, the storage rack can be pulled out and slidably inserted into the storage area, the number of the storage racks is one to eight layers, the storage racks are arranged in a vertical array, and each layer of the storage racks is provided with three to six groups of supporting parts, and the supporting parts are used to place slides.

[0015] By adopting the above technical solution, the storage rack can be pulled out from the storage area by pulling it out, so that it is convenient for staff to replenish slides on the storage rack, thereby improving operational convenience.

[0016] Optionally, the printing device includes an extrusion mechanism and a cover mechanism, the extrusion mechanism includes a sample loading box, a cell filter, an extrusion member and a first vertical driving member, the sample loading box is arranged on the housing, the top and bottom of the sample loading box are both open, the cell filter is fixed to the bottom of the sample loading box, the first vertical driving member is arranged on the housing, the extrusion member is located above the cell filter and is connected to the first vertical driving member, and the first vertical driving member is used to drive the extrusion member to move vertically;

[0017] The cover glass mechanism includes a moving assembly and a grabbing member. The moving assembly is arranged on the housing. The grabbing member is connected to the moving assembly. The moving assembly is used to grab the cover glass and place it on the slide coated with the tissue sample.

[0018] By adopting the above technical solution, excess tissue and other impurities in the tissue sample can be filtered through the cell filter, reducing interference with the detection and making the cells in the tissue evenly distributed on the slide.

[0019] Optionally, the extrusion mechanism further includes a second vertical driving member, a vertical through groove is provided on the top wall of the shell of the printing area, the sample loading box slides through the vertical through groove, the second vertical driving member is connected to the sample loading box, and the second vertical driving member is used to drive the sample loading box to slide vertically.

[0020] By adopting the above technical solution, the height of the sample loading box can be adjusted by the second vertical driving member, so that the cell filter can accurately fit the upper surface of the slide, allowing the tissue cells to fall smoothly on the slide.

[0021] Optionally, the cover glass mechanism further includes a accommodating box, which is fixed on the shell and used for stacking cover glasses. The moving assembly includes a translation drive and a lifting drive. The grabbing member is a first suction cup. The translation drive is connected to the lifting drive, and the translation drive is used to translate the lifting drive. The lifting drive is connected to the first suction cup, and the lifting drive is used to drive the first suction cup to lift and lower. The first suction cup is used to absorb and grab the cover glass located in the accommodating box.

[0022] By adopting the above technical solution, the cover glass is adsorbed and grasped by the first suction cup, thereby reducing damage to the cover glass during the grasping process.

[0023] Optionally, the conveying mechanism includes a transfer rack, a glass slide rack, a first screw rod, a first screw sleeve and a first driving member, the first screw rod is rotatably arranged in the shell, the first screw sleeve is fixed on the transfer rack, the first screw rod is threadedly connected to the first screw sleeve, the first driving member is fixed on the shell and connected to the first screw rod, the first driving member is used to drive the first screw rod to rotate, and the glass slide rack is detachably arranged on the transfer rack.

[0024] By adopting the above technical solution, the first driving member drives the first screw to rotate and transports the transfer rack, so that the moving position of the transfer rack can be accurately controlled.

[0025] Optionally, it also includes a telescopic mechanism, an inlet and outlet are provided on one side wall of the shell, the storage rack passes through the inlet and outlet and is slidably inserted in the shell, the telescopic mechanism includes a second screw rod, a second screw sleeve and a second driving member, the second screw rod is fixedly connected to the storage rack, the second screw sleeve is rotatably provided on the shell, the second driving member is fixedly provided on the shell and connected to the second screw sleeve, the second driving member is used to drive the second screw sleeve to rotate, and the second screw rod is threadedly connected to the second screw sleeve.

[0026] By adopting the above technical solution, the storage rack can be controlled to automatically extend out of the shell or retract into the shell through the telescopic mechanism, thereby improving the convenience of operation.

[0027] Optionally, it further includes a transfer mechanism, which includes a lifting member, a fourth driving member, a slide taking assembly, a lower limit member, a transmission gear, an upper limit member and a spring, the slide rack is provided with a guide groove, the lower limit member is slidably inserted in the guide groove, the lower limit member is provided with a tooth row, the transmission gear is rotatably arranged in the slide rack and meshes with the tooth row, the two ends of the spring are respectively fixed to the lower limit member and the inner wall of the guide groove, the upper limit member is detachably provided on the slide rack, the upper limit member is used to abut against the upper surface of the slide, and the lower limit member is used to support the slide;

[0028] The fourth driving member is fixed in the shell, the fourth driving member is connected to the lifting member, the fourth driving member is used to drive the lifting member to move vertically, the lifting member is provided with a vertical hole, the film taking assembly is slidably passed through the vertical hole, the film taking assembly is provided with a limiting portion, the lifting member is provided with a lower limit surface and an upper limit surface that can abut against the limiting portion, the film taking assembly is used to grab the slide located on the storage rack, the lifting member is provided with a rack that can engage with the transmission gear, the film taking assembly is provided with a magnet, and the magnet can be adsorbed and fixed to the bottom of the slide rack.

[0029] By adopting the above technical solution, the slides on the storage rack can be moved to the slide rack through the transfer mechanism, thereby eliminating the need for manual operation and effectively improving operational efficiency.

[0030] Optionally, the film picking assembly includes a column, an air pipe, a fifth driving member and a second suction cup. The cross-section of the column is square. The column is provided with a circular hole. The air pipe rotates through the circular hole. The fifth driving member is fixed on the column and connected to the air pipe. The fifth driving member is used to drive the air pipe to rotate around its own axis. The second suction cup is fixed to the upper end of the air pipe. The magnet is fixed on the column. The limiting part is a boss provided on the column.

[0031] By adopting the above technical solution, after the second suction cup absorbs and grabs the glass slide, the fifth driving member can drive the second suction cup to rotate, thereby adjusting the direction of the glass slide to meet the conveying direction of the conveying mechanism.

[0032] Optionally, a blocking member and a third driving member are further included, wherein a partition is provided in the shell, the sheet baking area is located in the shell on one side of the partition, and the sheet printing area, the printing area and the storage area are located in the shell on the other side of the partition, the partition is provided with a through hole for the transfer rack to pass through, the third driving member is fixed to the shell, the blocking member is connected to the third driving member, and the third driving member is used to drive the blocking member to open and close and block the through hole;

[0033] The shell is provided with a slice taking port which is connected with the slice roasting area and the outside of the shell. A cover plate is hingedly mounted on the shell, and the cover plate can be opened and closed to seal the slice taking port.

[0034] By adopting the above technical solution, the third driving member can drive the blocking member to block the through port, thereby reducing heat loss in the slice baking area during the slice baking process and lowering energy consumption.

[0035] In summary, the present application includes at least one of the following beneficial technical effects: placing a glass slide on a storage rack, and when tissue printing is required, moving the glass slide to the printing area through a conveying mechanism, printing a patient information label through a printing device, and then affixing the label to the glass slide, and then moving the glass slide to the printing area through a conveying mechanism, smearing tissue cells on the glass slide through a printing device, and covering it with a cover slip, and then moving the glass slide to the baking area through a conveying mechanism, baking the tissue cells, and fixing the tissue cells on the glass slide, thereby greatly improving the efficiency of tissue printing, effectively reducing the workload of staff, and alleviating the labor intensity of staff. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] Figure 1 A perspective view of this application;

[0037] Figure 2 This is a three-dimensional cross-sectional view from the first perspective of this application;

[0038] Figure 3 for Figure 2 A partial enlarged schematic diagram of part B;

[0039] Figure 4 This is a three-dimensional cross-sectional view from the second viewing angle of this application;

[0040] Figure 5 for Figure 4 A partial enlarged schematic diagram of part F in the middle;

[0041] Figure 6 A planar cross-sectional view from a third viewing angle of this application;

[0042] Figure 7 for Figure 6 A partial enlarged schematic diagram of part D in the middle;

[0043] Figure 8 for Figure 6 A partial enlarged schematic diagram of part E in the middle;

[0044] Figure 9 is the first state diagram of the transfer mechanism;

[0045] Figure 10 is the second state diagram of the transfer mechanism;

[0046] Figure 11 for Figure 1 A partial enlarged schematic diagram of part A;

[0047] Figure 12 This is a three-dimensional cross-sectional view from a fourth viewing angle of the present application;

[0048] Figure 13 for Figure 2 A partial enlarged schematic diagram of part C in the middle.

[0049] In the figure,

[0050] 10. Housing; 11. Storage area; 12. Printing area; 13. Film printing area; 14. Film baking area; 15. Film removal port; 16. Cover plate; 17. Opening; 18. Vertical through slot; 19. Through slot; 110. Inlet / outlet; 111. Bracket; 112. Partition; 1121. Through port; 113. Control panel; 114. Avoidance hole;

[0051] 20. Storage rack; 21. Supporting portion; 30. Conveying mechanism; 31. Transfer rack; 311. Positioning slot; 32. Slide rack; 321. Locking hole; 322. Guide slot; 323. Accommodating slot; 324. Screw hole; 325. Second avoidance slot; 33. First screw rod; 34. First screw sleeve; 35. First driving member;

[0052] 40. Printing device; 50. Printing device; 51. Extrusion mechanism; 511. Sample loading box; 512. Cell filter; 513. Extrusion member; 514. First vertical drive member; 515. Second vertical drive member; 516. First connecting rod; 517. Second connecting rod; 52. Covering mechanism; 521. Moving assembly; 5211. Translational drive member; 5212. Lifting drive member; 522. Grabbing member; 523. Accommodating box;

[0053] 60. Heating element; 70. Push-pull electromagnet; 71. Moving slide; 80. Telescopic mechanism; 81. Second screw rod; 82. Second screw sleeve; 83. Second driving element; 84. Belt drive structure; 85. Bearing assembly;

[0054] 90. Transfer mechanism; 91. Lifting member; 911. Vertical hole; 912. Lower limit surface; 913. Upper limit surface; 914. Rack; 92. Fourth driving member; 93. Sheet fetching assembly; 931. Cylinder; 9311. Circular hole; 932. Air pipe; 9321. Baffle; 9322. Air nozzle; 933. Fifth driving member; 934. Second suction cup; 935. Magnet; 936. Third connecting rod; 937. Limiting portion; 938. Gear pair; 94. Lower limit member; 941. Gear row; 942. First avoidance groove; 95. Transmission gear; 96. Upper limit member; 961. Through hole; 97. Spring; 98. Locking bolt;

[0055] 100 , blocking member; 120 , third driving member; 121 , output shaft; 130 , slide glass. DETAILED DESCRIPTION

[0056] The following is combined with Figure 1 -Attached Figure 13 , further details of this application are given.

[0057] The embodiment of the present application discloses a tissue printer.

[0058] Reference Figure 1 and Figure 2 A tissue printer includes a shell 10, a storage rack 20, a conveying mechanism 30, a printing device 40, a printing device 50 and a heating element 60. The shell 10 is provided with a storage area 11, a printing area 12, a printing area 13 and a baking area 14. The shell 10 is provided with a control panel 113, through which parameter settings and other operations can be performed.

[0059] Storage racks 20 are located in storage area 11 and are used to store blank slides. Racks 20 can be inserted and slidably inserted into storage area 11. Racks 20 are arranged in a vertical array, with one to eight layers. Each layer of racks 20 is equipped with three to six sets of supporting portions 21 for holding slides 130. The supporting portions 21 can be formed by grooves located in the upper portion of the racks 20.

[0060] Reference Figure 2 and Figure 3 When a slide needs to be placed on the storage rack 20, the storage rack 20 can be manually pulled out of the storage area 11. After the slide is placed on the storage rack 20, the storage rack 20 can be pushed back into the storage area 11. In addition to manually pulling out the storage rack 20, the storage rack 20 can also be automatically pulled out using the telescopic mechanism 80. In this case, the specific connection relationship between the storage rack 20 and the housing 10, as well as the specific structure of the telescopic mechanism 80, are as follows:

[0061] An inlet and outlet 110 is provided on one side wall of the housing 10. The storage rack 20 passes through the inlet and outlet 110 and is slidably inserted into the housing 10. More specifically, a bracket 111 is fixedly provided on the inner bottom wall of the housing 10. The bracket 111 is provided with a guide rail. The storage rack 20 is frame-shaped. Slide grooves are provided on both sides of the storage rack 20. The storage rack 20 is slidably clamped on the guide rails through the slide grooves. The telescopic mechanism 80 is provided with two groups. The telescopic mechanism 80 includes a second screw rod 81, a second screw sleeve 82 and a second driving member 83. The second screw rod 81 is fixedly connected to the storage rack 20. The second screw sleeve 82 is rotatably provided on the housing 10 via a bearing assembly 85. The second driving member 83 is fixedly provided on the housing 10 and connected to the second screw sleeve 82. The second driving member 83 is used to drive the second screw sleeve 82 to rotate. The second screw rod 81 is screwed to the second screw sleeve 82. The housing 10 is provided with an avoidance hole 114 for the second screw rod 81 to pass through. The second driving member 83 can adopt a second motor, and the second motor can be connected to the second screw sleeve 82 through a belt transmission structure 84. When the second motor drives the second screw sleeve 82 to rotate, it can drive the second screw rod 81 to move along its axial direction, thereby driving the storage rack 20 to slide along the guide rail.

[0062] Reference Figure 2 and Figure 3 The conveying mechanism 30 is arranged in the shell 10, and the conveying mechanism 30 is used to transfer the slides from the storage rack 20 between the storage area 11, the printing area 12, the printing area 13 and the baking area 14.

[0063] Reference Figure 4 and Figure 5 The specific structure of the conveying mechanism 30 is as follows: the conveying mechanism 30 is provided with two groups, and the conveying mechanism 30 includes a transfer frame 31, a glass slide frame 32, a first screw rod 33, a first screw sleeve 34 and a first driving member 35. The first screw rod 33 is rotatably arranged in the housing 10, and the first screw sleeve 34 is fixed on the transfer frame 31. The first screw rod 33 and the first screw sleeve 34 are screwed together. Figure 3 The first driving member 35 is fixed on the shell 10 and connected to the first screw rod 33. The first driving member 35 can adopt a first motor, which can drive the first screw rod 33 to rotate. When the first screw rod 33 rotates, the transfer frame 31 can be driven to move along the axial direction of the first screw rod 33 under the interaction between the first screw rod 33 and the first screw sleeve 34.

[0064] Reference Figure 6 and Figure 7The slide rack 32 is detachably mounted on the transport rack 31. More specifically, the transport rack 31 is provided with a positioning slot 311, into which the slide rack 32 is placed. A push-pull electromagnet 70 is fixedly mounted on the transport rack 31, and a locking hole 321 is provided on the slide rack 32 for inserting a movable slide rod 71 of the push-pull electromagnet 70. Once the slide rack 32 is positioned in the positioning slot 311 of the transport rack 31, the movable slide rod 71 of the push-pull electromagnet 70 is extended and inserted into the locking hole 321, thereby securing the slide rack 32 to the transport rack 31.

[0065] When the glass slides are transported between the storage area 11, the printing area 12, the printing area 13, and the baking area 14 by the conveying mechanism 30, the glass slides on the storage rack 20 need to be transferred to the glass slide rack 32 by the transfer mechanism 90. The specific structure of the transfer mechanism 90 is as follows:

[0066] Reference Figure 6 and Figure 7 The transfer mechanism 90 includes a lifting member 91, a fourth driving member 92, a film taking assembly 93, a lower limit member 94, a transmission gear 95, an upper limit member 96, a spring 97 and a locking bolt 98. The transfer rack 31 and the glass slide rack 32 are both frame-shaped. A guide groove 322 is provided on the glass slide rack 32. The lower limit member 94 is slidably inserted in the guide groove 322. A tooth row 941 is provided on the lower limit member 94. The glass slide rack 32 is provided with a receiving groove 323 connected to the guide groove 322. The transmission gear 95 is rotatably arranged in the receiving groove 323 of the glass slide rack 32 and engages with the tooth row 941. The two ends of the spring 97 are respectively fixed to the lower limit member 94 and the inner wall of the guide groove 322. The upper limit member 96 is detachably mounted on the slide holder 32. More specifically, the upper limit member 96 defines a through hole 961, and the slide holder 32 defines a screw hole 324. A locking bolt 98 passes through the through hole 961 and is screwed into the screw hole 324. The upper limit member 96 is configured to abut against the upper surface of the slide 130, while the lower limit member 94 is configured to support the slide 130.

[0067] Reference Figure 6 and Figure 8The fourth driving member 92 is fixed in the shell 10 and is connected to the lifting member 91. The fourth driving member 92 is used to drive the lifting member 91 to move vertically. The fourth driving member 92 can adopt a fourth cylinder. More specifically, the fourth cylinder is fixed on the inner bottom wall of the shell 10, and the lifting member 91 is fixed to the fourth piston rod of the fourth cylinder. The lifting member 91 is provided with a vertical hole 911, and the film taking assembly 93 is slidably inserted into the vertical hole 911. The film taking assembly 93 is provided with a limiting portion 937. The lifting member 91 is provided with a lower limiting surface 912 and an upper limiting surface 913 that can abut against the limiting portion 937. The film taking assembly 93 is used to grab the slide 130 located on the storage rack 20. The lifting member 91 is provided with a rack 914 that can engage with the transmission gear 95. The lower limiting member 94 is provided with a first avoidance groove 942 corresponding to the rack 914, and the glass slide rack 32 is provided with a second avoidance groove 325 corresponding to the rack 914. The film taking assembly 93 is provided with a magnet 935, and the magnet 935 can be adsorbed and fixed to the bottom of the glass slide rack 32.

[0068] Reference Figure 8 The specific structure of the film removal assembly 93 is as follows: the film removal assembly 93 includes a column 931, an air tube 932, a fifth driving member 933, and a second suction cup 934. The cross-section of the column 931 is square. The column 931 is provided with a circular hole 9311. The air tube 932 is rotatably inserted into the circular hole 9311. The air tube 932 is provided with a baffle 9321 to prevent it from escaping from the circular hole 9311. The fifth driving member 933 is fixed to the column 931 and connected to the air tube 932. The fifth driving member 933 is used to drive the air tube 932 to rotate around its own axis. The fifth driving member 933 can be a fifth motor. More specifically, the fifth motor is connected to the air tube 932 via a gear pair 938. The second suction cup 934 is fixed to the upper end of the air tube 932. The lower end of the air tube 932 is provided with an air nozzle 9322. The second suction cup 934 can be connected to a vacuum pump through the air nozzle 9322 to achieve negative pressure adsorption of the slide. The magnet 935 is fixed on the column 931 through the third connecting rod 936 , and the limiting portion 937 is a boss provided on the column 931 .

[0069] The specific steps of transferring the slides on the storage rack 20 to the slide rack 32 by the transfer mechanism 90 are as follows: Figure 9First, the storage rack 20 is moved by the telescopic mechanism 80, and the glass slide on the storage rack 20 is moved above the second suction cup 934. Then, the fourth driving member 92 drives the lifting member 91 to move vertically upward, and the second suction cup 934 absorbs and grabs the glass slide 130. Then, the fifth driving member 933 drives the air pipe 932 to rotate 90 degrees, and the fourth driving member 92 drives the lifting member 91 to move vertically upward, so that the rack 914 passes through the glass slide rack 32 and engages with the transmission gear 95. When the rack 914 moves upward, the transmission gear 95 and the gear row 941 drive the lower limit member 94 to retreat into the guide groove 322. Then the lifting member 91 continues to move upward until the upper surface of the glass slide 130 abuts against the upper limit member 96. At this time, the magnet 935 is just absorbed and fixed to the bottom of the glass slide rack 32, forming a position as shown in the figure. Figure 9 The status shown.

[0070] Reference Figure 10 Then, the fourth driving member 92 drives the lifting member 91 to move vertically downward, so that the rack 914 is separated from the transmission gear 95. At this time, the lower limit member 94 extends out of the guide groove 322 and supports the slide 130. Then the lifting member 91 continues to move downward until the upper limit surface 913 contacts the limit portion 937, forming a Figure 10 In the state shown, the adsorption effect of the second suction cup 934 on the glass slide 130 is cancelled, and then the lifting member 91 continues to move downward, and the lifting member 91 drives the column 931 to move downward, so that the magnet 935 is separated from the bottom of the glass slide rack 32, and at the same time the second suction cup 934 is separated from the glass slide 130, and the glass slide 130 is stuck between the lower limit surface 912 and the upper limit surface 913, and the glass slide 130 on the storage rack 20 is transferred to the glass slide rack 32.

[0071] Reference Figure 1 The printing device 40 is provided at the printing area 12, and the patient information label can be printed by the printing device 40. An opening 17 is provided on the top wall of the shell 10 at the printing area 12, and the printed patient information label can be manually pasted on the slide through the opening 17.

[0072] Reference Figure 11 and Figure 12 The printing device 50 is provided at the printing area 13 , and is used to apply the tissue sample on the slide 130 and cover it with a cover glass.

[0073] The specific structure of the printing device 50 is as follows: the printing device 50 includes an extrusion mechanism 51 and a cover mechanism 52. The extrusion mechanism 51 includes a sample loading box 511, a cell filter 512, an extrusion member 513, a first vertical drive member 514 and a second vertical drive member 515. The sample loading box 511 is arranged on the shell 10. The top and bottom of the sample loading box 511 are both open. The cell filter 512 is fixed to the bottom of the sample loading box 511. The first vertical drive member 514 is arranged on the shell 10. The extrusion member 513 is located above the cell filter 512 and is connected to the first vertical drive member 514. The first vertical drive member 514 is used to drive the extrusion member 513 to move vertically. The first vertical drive member 514 can adopt a first vertical cylinder. More specifically, the extrusion member 513 is fixed to the first cylinder rod of the first vertical cylinder through a first connecting rod 516.

[0074] A vertical through slot 18 is provided on the top wall of the shell 10 of the printing area 13, and the sample loading box 511 is slidably inserted into the vertical through slot 18. The second vertical driving member 515 is connected to the sample loading box 511. The second vertical driving member 515 is used to drive the sample loading box 511 to slide vertically. The second vertical driving member 515 can adopt a second vertical cylinder. More specifically, the sample loading box 511 is fixedly connected to the second cylinder rod of the second vertical cylinder through a second connecting rod 517.

[0075] When performing tissue cell printing, a tissue sample is added to the sample loading box 511, and the height of the sample loading box 511 is adjusted by the second vertical driving member 515 so that the cell filter 512 is in contact with the upper surface of the slide. The first vertical driving member 514 drives the squeezing member 513 downward to squeeze the tissue sample in the sample loading box 511, so that the tissue cells pass through the cell filter 512 and are coated on the upper surface of the slide.

[0076] The cover glass mechanism 52 includes a moving assembly 521, a grabbing member 522 and a accommodating box 523. The moving assembly 521 is provided on the housing 10. The grabbing member 522 is connected to the moving assembly 521. The moving assembly 521 is used to grab the cover glass and place it on the slide 130 coated with the tissue sample.

[0077] The storage box 523 is fixed to the housing 10 and is used to stack cover glasses. The moving assembly 521 includes a translation driver 5211 and a lifting driver 5212. The gripping member 522 is a first suction cup. The translation driver 5211 is connected to the lifting driver 5212 and is used to translate the lifting driver 5212. The lifting driver 5212 is connected to the first suction cup, which is used to drive the first suction cup to move upward and downward. The first suction cup is used to absorb and grasp the cover glass in the storage box 523. The translation driver 5211 can be a first pneumatic cylinder fixed to the housing 10. The lifting driver 5212 can be a second pneumatic cylinder, which is fixed to the first piston rod of the first cylinder, and the first suction cup is fixed to the second piston rod of the second cylinder. A through slot 19 for the cover glass to pass through is provided on the top wall of the housing 10 in the printing area 13.

[0078] After the tissue cells are spread on the upper surface of the slide through the cell filter 512 by the squeezing mechanism 51, the cover glass in the accommodating box 523 is grasped by the first suction cup, and the cover glass is placed on the slide coated with the tissue cells by the moving component 521.

[0079] Reference Figure 2 A heating element 60 is disposed within the slice baking area 14. The heating element 60 heats the glass slide 130 coated with tissue cells, thereby fixing the tissue cells on the slide. The heating element 60 can be a resistance heater, an infrared heater, or a dielectric heater. The housing 10 is provided with a slide removal port 15 that communicates with the slice baking area 14 and the exterior of the housing 10. A cover 16 is hingedly mounted on the housing 10. The cover 16 can be opened and closed to seal the slide removal port 15. When heating is complete, the cover 16 can be opened and the glass slide carrying the tissue cells can be removed from the slice baking area 14 through the slide removal port 15.

[0080] Reference Figure 12 and Figure 13 A partition 112 is provided in the shell 10, the sheet baking area 14 is located in the shell 10 on one side of the partition 112, the sheet printing area 13, the printing area 12 and the storage area 11 are located in the shell 10 on the other side of the partition 112, and the partition 112 is provided with a through opening 1121 for the transfer rack 31 to pass through.

[0081] In order to prevent the heat loss in the grilling area 14, a blocking member 100 can be set to block the through-port 1121, and a third driving member 120 can be set to control the opening and closing of the blocking member 100. More specifically, the third driving member 120 is fixed on the shell 10, and the blocking member 100 is connected to the third driving member 120. The third driving member 120 can adopt a third motor. More specifically, the blocking member 100 is plate-shaped, and the plate-shaped blocking member 100 is fixed to the output shaft 121 of the third motor. The third motor can drive the blocking member 100 to rotate and open and close to block the through-port 1121.

[0082] The operating principle of the tissue slide printer of this embodiment is as follows: when tissue slide printing is required, the transfer mechanism 90 transfers the slides from the storage rack 20 in the storage area 11 to the slide rack 32. The transport mechanism 30 then moves the transport rack 31 and the slide rack 32 to the printing area 12. The printing device 40 prints a patient information label, which is then affixed to the slide. The transport mechanism 30 then moves the transport rack 31 and the slide rack 32 to the printing area 13. The second vertical drive 515 adjusts the height of the sample loading box 511 so that the cell filter 512 is in contact with the upper surface of the slide. A tissue sample is added to the sample loading box 511. The first vertical drive 514 then drives the extrusion member 513 downward to extrude the tissue sample in the sample loading box 511, allowing the tissue cells to pass through the cell filter 512 and be coated on the upper surface of the slide. The transport rack 31 and slide rack 32 are then moved by the conveyor mechanism 30 to below the through slot 19. The first suction cup grasps the cover glass in the receiving box 523 and places the cover glass on the slide coated with tissue cells via the moving assembly 521. The transport rack 31 and slide rack 32 are then moved by the conveyor mechanism 30 through the through port 1121 into the slide-baking area 14. The slide coated with tissue cells is heated by the heater 60 to fix the tissue cells on the slide. After heating is complete, the cover plate 16 is opened and the slide coated with tissue cells is removed from the slide-baking area 14 through the slide removal port 15, completing the tissue print.

[0083] The examples of this specific embodiment are all preferred embodiments of this application and are not intended to limit the scope of protection of this application. Identical components are represented by the same reference numerals. Therefore, any equivalent changes made based on the structure, shape, and principle of this application should be included in the scope of protection of this application.

Claims

1. A tissue printer, characterized in that: The invention comprises a housing (10), a storage rack (20), a conveying mechanism (30), a printing device (40), a printing device (50) and a heating element (60), wherein the housing (10) is provided with a storage area (11), a printing area (12), a printing area (13) and a baking area (14); the storage rack (20) is provided at the storage area (11), and the storage rack (20) is used to store and place the slide glass (130); the conveying mechanism (30) is provided in the housing (10), and the conveying mechanism (30) is used to transfer the slide glass (130) from the storage rack (20) to the heating element (60). 30) is transported between the storage area (11), the printing area (12), the printing area (13) and the baking area (14); the printing device (40) is provided at the printing area (12), and the printing device (40) is used to print patient information; the printing device (50) is provided at the printing area (13), and the printing device (50) is used to apply the tissue sample on the slide (130) and cover it with a cover glass; the heating element (60) is provided in the baking area (14), and the heating element (60) is used to heat the slide (130) coated with the tissue sample ) for heating; the printing device (50) includes an extrusion mechanism (51) and a cover mechanism (52), the extrusion mechanism (51) includes a sample loading box (511), a cell filter (512), an extrusion member (513) and a first vertical driving member (514), the sample loading box (511) is arranged on the shell (10), the top and bottom of the sample loading box (511) are both open, the cell filter (512) is fixed to the bottom of the sample loading box (511), the first vertical driving member (514) is arranged on the shell (10), the extrusion member (513) is located above the cell filter (512) and is connected to the first vertical driving member (514), and the first vertical driving member (514) is used to drive the extrusion member (513) to move vertically; the cover mechanism (52) includes a moving component (521) and a grabbing member (522), the moving component (521) is provided on the shell (10), the grabbing member (522) is connected to the moving component (521), and the moving component (521) is used to grab the cover glass and cover it on the slide (130) coated with the tissue sample.

2. A tissue printer according to claim 1, characterized in that: The storage racks (20) can be inserted into the storage area (11) in a pull-out sliding manner. The number of the storage racks (20) is one to eight layers. The storage racks (20) are arranged in a vertical array. Each layer of the storage racks is provided with three to six groups of supporting parts (21), and the supporting parts (21) are used to place slides (130).

3. A tissue printer according to claim 1, characterized in that: The extrusion mechanism (51) further includes a second vertical driving member (515). A vertical through slot (18) is provided on the top wall of the housing (10) of the printing area (13). The sample loading box (511) is slidably inserted into the vertical through slot (18). The second vertical driving member (515) is connected to the sample loading box (511). The second vertical driving member (515) is used to drive the sample loading box (511) to slide vertically.

4. A tissue printer according to claim 1, characterized in that: The cover glass mechanism (52) further comprises a accommodating box (523), the accommodating box (523) being fixedly mounted on the housing (10), the accommodating box (523) being used for stacking cover glasses, the moving assembly (521) comprising a translation drive member (5211) and a lifting drive member (5212), the grabbing member (522) being a first suction cup, the translation drive member (5211) being connected to the lifting drive member (5212), the translation drive member (5211) being used for translating the lifting drive member (5212), the lifting drive member (5212) being connected to the first suction cup, the lifting drive member (5212) being used for driving the first suction cup to move upward and downward, and the first suction cup being used for adsorbing and grabbing the cover glass in the accommodating box (523).

5. A tissue printer according to claim 1, characterized in that: The conveying mechanism (30) includes a transfer rack (31), a glass slide rack (32), a first screw rod (33), a first screw sleeve (34) and a first driving member (35), wherein the first screw rod (33) is rotatably arranged in the housing (10), the first screw sleeve (34) is fixed on the transfer rack (31), the first screw rod (33) and the first screw sleeve (34) are screwed together, the first driving member (35) is fixed on the housing (10) and connected to the first screw rod (33), the first driving member (35) is used to drive the first screw rod (33) to rotate, and the glass slide rack (32) is detachably arranged on the transfer rack (31).

6. A tissue printer according to claim 1, characterized in that: The invention also includes a telescopic mechanism (80), an inlet and outlet (110) is provided on one side wall of the shell (10), the storage rack (20) passes through the inlet and outlet (110) and is slidably inserted into the shell (10), the telescopic mechanism (80) includes a second screw rod (81), a second screw sleeve (82) and a second driving member (83), the second screw rod (81) is fixedly connected to the storage rack (20), the second screw sleeve (82) is rotatably provided on the shell (10), the second driving member (83) is fixedly provided on the shell (10) and connected to the second screw sleeve (82), the second driving member (83) is used to drive the second screw sleeve (82) to rotate, and the second screw rod (81) is screwed to the second screw sleeve (82).

7. A tissue printer according to claim 5, characterized in that: The transfer mechanism (90) further comprises a lifting member (91), a fourth driving member (92), a film taking assembly (93), a lower limit member (94), a transmission gear (95), an upper limit member (96) and a spring (97). The slide rack (32) is provided with a guide groove (322), the lower limit member (94) is slidably inserted in the guide groove (322), the lower limit member (94) is provided with a tooth row (941), the transmission gear (95) is provided with a lower limit member (96) and a spring (97). The movable gear (95) is rotatably arranged in the slide rack (32) and meshes with the tooth row (941). The two ends of the spring (97) are respectively fixed to the lower limit member (94) and the inner wall of the guide groove (322). The upper limit member (96) is detachably arranged on the slide rack (32). The upper limit member (96) is used to abut against the upper surface of the slide (130). The lower limit member (94) is used to support the slide (130). The fourth driving member (92) is fixed in the housing (10), the fourth driving member (92) is connected to the lifting member (91), the fourth driving member (92) is used to drive the lifting member (91) to move vertically, the lifting member (91) is provided with a vertical hole (911), the film taking assembly (93) is slidably passed through the vertical hole (911), the film taking assembly (93) is provided with a limiting portion (937), and the lifting member (91) is provided with a The lower limit surface (912) and the upper limit surface (913) are capable of abutting against the limit portion (937), the film taking assembly (93) is used to grab the slide (130) located on the storage rack (20), the lifting member (91) is provided with a rack (914) capable of meshing with the transmission gear (95), and the film taking assembly (93) is provided with a magnet (935), and the magnet (935) can be adsorbed and fixed to the bottom of the slide rack (32).

8. A tissue printer according to claim 7, characterized in that: The film taking assembly (93) includes a column (931), an air tube (932), a fifth driving member (933) and a second suction cup (934). The cross section of the column (931) is square. The column (931) is provided with a circular hole (9311). The air tube (932) is rotatably inserted into the circular hole (9311). The fifth driving member (933) is fixed on the column (931) and connected to the air tube (932). The fifth driving member (933) is used to drive the air tube (932) to rotate around its own axis. The second suction cup (934) is fixed on the upper end of the air tube (932). The magnet (935) is fixed on the column (931). The limiting portion (937) is a boss provided on the column (931).

9. The tissue printer according to claim 5, characterized in that: The invention also includes a blocking member (100) and a third driving member (120). A partition (112) is provided in the shell (10). The baking area (14) is located in the shell (10) on one side of the partition (112). The printing area (13), the printing area (12) and the storage area (11) are located in the shell (10) on the other side of the partition (112). The partition (112) is provided with a through hole (1121) for the transfer rack (31) to pass through. The third driving member (120) The blocking member (100) is fixed on the shell (10), and is connected to the third driving member (120). The third driving member (120) is used to drive the blocking member (100) to open and close and block the through port (1121). The shell (10) is provided with a slice taking port (15) connected to the slice roasting area (14) and the outside of the shell (10). A cover plate (16) is hingedly mounted on the shell (10), and the cover plate (16) can be opened and closed to block the slice taking port (15).

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