A synergistic adjuvant and indoxacarb·lufenuron liquid formulation

Abstract

The present invention belongs to the technical field of pesticides, and specifically relates to a synergistic adjuvant and a indoxacarb·chlorfluazuron liquid formulation. The synergistic adjuvant includes citronella oil, mineral oil, and isomeric alcohol polyoxyethylene ether. The weight ratio of citronella oil, mineral oil, and isomeric alcohol polyoxyethylene ether is 2-6:6-10:3-8. When the synergistic adjuvant is used in the indoxacarb·chlorfluazuron liquid formulation, it can significantly reduce the surface tension of the pesticide, increase the permeability and adhesion of the pesticide, thereby playing a synergistic role.

Description

Technical Field

[0001] The present invention belongs to the technical field of pesticides, and particularly relates to a synergistic adjuvant and an indoxacarb·chlorfluazuron liquid preparation. Background Art

[0002] In the process of crop cultivation, pesticides are basically indispensable. Chemical pesticides have a quick control effect, can quickly control the occurrence of pests and diseases, and ensure the high yield of crops. Indoxacarb belongs to the oxadiazine class of insecticides and has a unique mechanism of action. It is rapidly converted into N-desmethoxycarbonyl metabolite in insects and then irreversibly blocks the sodium channel, thereby exerting insecticidal activity. Indoxacarb began to be registered and used in 1998. Chlorfluazuron belongs to the benzoylurea class of insecticides and is a chitin synthesis inhibitor. In 1993, Syngenta first launched chlorfluazuron in France.

[0003] Patent CN 101485329 B applied for an insecticidal pesticide composition of indoxacarb and chlorfluazuron in 2009. Compared with single agents, it improved the control effect, reduced the dosage, and expanded the control spectrum. Resistance is a problem faced after the use of any insecticide, and indoxacarb and chlorfluazuron are no exception. With the unscientific use of indoxacarb and chlorfluazuron for a long time, many pests have developed varying degrees of resistance to them. This has led to the arbitrary increase in the amount of pesticides used in order to achieve the desired control effect, increasing the cost of using pesticides and causing environmental pollution. For conventional indoxacarb and chlorfluazuron pesticide insecticides, due to the large surface tension of the liquid medicine during use, the droplets cannot effectively wet, spread, and adhere to the target leaf surface, resulting in more loss of the liquid medicine and poor drug efficacy. Summary of the Invention

[0004] In order to improve the control effect of indoxacarb and chlorfluazuron liquid preparations, delay resistance, reduce the dosage, and protect the ecological environment, the present invention provides a synergistic adjuvant and an indoxacarb·chlorfluazuron liquid preparation. The synergistic adjuvant for the indoxacarb·chlorfluazuron liquid preparation is obtained by compounding citronella oil, mineral oil, and isomeric alcohol polyoxyethylene ether, which can significantly reduce the surface tension of the indoxacarb and chlorfluazuron liquid medicine, increase the permeability of the agent, and quickly penetrate the insect body, thereby playing a synergistic role.

[0005] The technical solution of the present invention is as follows:

[0006] A synergistic adjuvant for an indoxacarb·chlorfluazuron liquid preparation, comprising citronella oil, mineral oil, and isomeric alcohol polyoxyethylene ether, and the weight ratio of citronella oil, mineral oil, and isomeric alcohol polyoxyethylene ether is 2-6:6-10:3-8.

[0007] As a specific embodiment, the number of carbon atoms of the isomeric alcohol in the isomeric alcohol polyoxyethylene ether is C9-C12, and the number of EO is 6-8.

[0008] Since the length of the alkyl chain and the degree of EO polymerization in isomeric alcohol polyoxyethylene ether can affect the ability of isomeric alcohol polyoxyethylene ether to reduce surface tension, the number of carbon atoms in the isomeric alcohol of isomeric alcohol polyoxyethylene ether is C9-C12, and the number of EO is 6-8.

[0009] A indoxacarb·chlorfluazuron liquid formulation comprises active ingredients and auxiliaries. The auxiliaries include one or more of a dispersant, a wetting agent, an emulsifier, an antifreeze, a thickener, an antifoaming agent, and a synergistic auxiliary. The synergistic auxiliary includes citronella oil, mineral oil, and isomeric alcohol polyoxyethylene ether. The weight ratio of citronella oil, mineral oil, and isomeric alcohol polyoxyethylene ether is 2-6:6-10:3-8.

[0010] A indoxacarb·chlorfluazuron liquid formulation comprises active ingredients and auxiliaries. The auxiliaries include one or more of a dispersant, a wetting agent, an emulsifier, an antifreeze, a thickener, an antifoaming agent, and a synergistic auxiliary. The synergistic auxiliary includes citronella oil, mineral oil, and isomeric alcohol polyoxyethylene ether. The weight ratio of citronella oil, mineral oil, and isomeric alcohol polyoxyethylene ether is 2-6:6-10:3-8; the number of carbon atoms in the isomeric alcohol of the isomeric alcohol polyoxyethylene ether is C9-C12, and the number of EO is 6-8.

[0011] As a specific embodiment, the content of the synergistic auxiliary is 5-8%.

[0012] As a specific embodiment, the content of the active ingredients indoxacarb and chlorfluazuron is 12-22%.

[0013] As a specific embodiment, the liquid formulation is a suspension concentrate or a microemulsion.

[0014] As a specific embodiment, the dispersant is one or several of polycarboxylate dispersants and high molecular amphiphilic anionic-nonionic surfactants.

[0015] As a specific embodiment, the wetting agent is a modified alkylphenol polyoxyethylene ether wetting agent.

[0016] As a specific embodiment, the antifoaming agent is a polysiloxane antifoaming agent; the thickener is one or two of xanthan gum and silica white, and the antifreeze is ethylene glycol.

[0017] As a specific embodiment, the emulsifier is one or several of fatty alcohol polyoxyethylene ether phosphate and polyoxypropylene-polyoxyethylene block polymer

[0018] Indoxacarb and lufenuron have contact and stomach poisoning effects. Only by reducing the surface tension of the pesticide, reducing the loss of the pesticide, lowering the surface tension of the indoxacarb and lufenuron liquid medicine, and improving the permeability of the pesticide can the pesticide quickly contact the pests and enter their bodies, so as to effectively control the pests. After repeated experiments, the inventor finally obtained a synergistic adjuvant suitable for the indoxacarb·lufenuron liquid formulation. Among them, mineral oil can improve the permeability of the pesticide, isomeric alcohol polyoxyethylene ether can reduce the surface tension of the pesticide, and citronella oil can dissolve the body wall of the pests, enabling the pesticide to quickly enter the insect body. The combination of three synergistic adjuvants with different action mechanisms can significantly reduce the surface tension of the pesticide, improve the permeability of the pesticide, and quickly penetrate the insect body wall, thereby improving the control effect of the pesticide.

[0019] The synergistic adjuvant provided by the present invention can increase the wetting and permeability of the indoxacarb·lufenuron liquid formulation and the dissolution ability of the pest body wall when added to the indoxacarb·lufenuron liquid formulation. At the same time, it reduces the surface tension of the liquid medicine, significantly improves the control effect of the indoxacarb·lufenuron liquid formulation, reduces the dosage of the pesticide, and is beneficial to extending the life cycle of the pesticide. Specific Embodiments

[0020] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0021] The experimental methods used in the following examples and comparative examples are all conventional methods unless otherwise specified, and the following percentages are weight percentages.

[0022] The materials, reagents, etc. used in the following examples and comparative examples can be obtained from commercial channels unless otherwise specified.

[0023] SP-27001 and SP-SC29 used in the following examples and comparative examples are purchased from Jiangsu Qingyu Chemical Technology Co., Ltd.; GY-D07 is purchased from Beijing Guangyuan Yinuo Chemical Co., Ltd.; 860P is purchased from SOLVAY; Sag 1522 is purchased from Momentive Performance Materials Inc.; other raw materials are all products that can be easily purchased on the market.

[0024] Example 1: 12% Indoxacarb·Lufenuron Suspension Concentrate

[0025] Indoxacarb, 8%; Lufenuron, 4%; Dispersant SP-SC29, 2%; GY-D07, 3%; Wetting agent 860P, 1%; Emulsifier, AEO-7P, 2%, 1601, 4%; Defoamer Sag 1522, 0.3%; Antifreeze ethylene glycol, 4%; Thickener xanthan gum, 0.1%, silica white, 1.5%; Synergistic adjuvant: Citronella oil 1%, mineral oil 3%, isomeric alcohol polyoxyethylene ether (C9\EO8) 3%; Deionized water 63.1%.

[0026] Example 2: 12% Indoxacarb·Lufenuron Suspension Concentrate

[0027] Indoxacarb, 8%; Lufenuron, 4%; Dispersant SP-SC29, 2%, GY-D07, 3%; Wetting agent 860P, 1%; Emulsifier, AEO-7P, 2%, 1601, 4%; Defoamer Sag 1522, 0.3%; Antifreeze ethylene glycol, 4%; Thickener xanthan gum, 0.1%, silica white, 1.5%; Synergistic adjuvant: Citronella oil 1%, mineral oil 4%, isomeric alcohol polyoxyethylene ether (C11\EO7) 3%; Deionized water 62.1%.

[0028] Example 3: 12% Indoxacarb·Lufenuron Suspension Concentrate

[0029] Indoxacarb, 8%; Lufenuron, 4%; Dispersant SP-SC29, 2%, SP-27001, 3%; Wetting agent 860P, 1%; Emulsifier, AEO-7P, 4%, 1601, 2%; Defoamer Sag 1522, 0.3%; Antifreeze ethylene glycol, 4%; Thickener xanthan gum, 0.1%, silica white, 1.5%; Synergistic adjuvant: Citronella oil 1.5%, mineral oil 4.5%, isomeric alcohol polyoxyethylene ether (C8\EO6) 2%; Deionized water, 62.1%.

[0030] For the above Examples 1-3, the preparation method of the 12% Indoxacarb·Lufenuron Suspension Concentrate specifically includes the following steps:

[0031] (1) Add water, dispersant, wetting agent, emulsifier, synergistic adjuvant, defoamer, and antifreeze into the reaction kettle according to the ratio, and stir to mix them evenly;

[0032] (2) Add the indoxacarb technical material, lufenuron technical material, and thickener into the reaction kettle according to the ratio, and stir and shear to mix them evenly to obtain a mixed solution;

[0033] (3) Add the mixed solution obtained in step (2) into a sand mill for grinding until the particle size D90 = 5um, and the 12% Indoxacarb·Lufenuron Suspension Concentrate is obtained after grinding is completed.

[0034] Comparative Example 1: 12% Indoxacarb·Lufenuron Suspension Concentrate

[0035] Indoxacarb, 8%; Chlorfluazuron, 4%; Dispersant SP-SC29, 2%; GY-D07, 3%; Wetting agent 860P, 1%; Emulsifier, AEO-7P, 2%, 1601, 4%; Defoamer Sag 1522, 0.3%; Antifreeze ethylene glycol, 4%; Thickener xanthan gum, 0.1%, silica white, 1.5%; Deionized water 70.1%.

[0036] Compared with Example 1, Cymbopogon citratus oil, mineral oil, and isomeric alcohol polyoxyethylene ether were not added in Comparative Example 1. Comparative Example 2: 12% Indoxacarb·Chlorfluazuron Suspension Concentrate

[0037] The 12% Indoxacarb·Chlorfluazuron Suspension Concentrate was prepared according to the method provided in Patent CN101485329B in Comparative Example 2. The specific formula is as follows:

[0038] Indoxacarb, 8%; Chlorfluazuron, 4%; Sodium methylnaphthalenesulfonate formaldehyde condensate, 10%; Xanthan gum, 1%; Bentonite, 1%; Glycerol, 5%; Deionized water, 71%.

[0039] The active ingredients, dispersant, wetting agent, water and other components were mixed evenly according to the ratio of the formula, and after grinding, 12% Indoxacarb·Chlorfluazuron Suspension Concentrate was obtained.

[0040] Compared with Example 1, Cymbopogon citratus oil, mineral oil, and isomeric alcohol polyoxyethylene ether synergistic auxiliaries were not added in Comparative Example 2, and the auxiliaries were different.

[0041] Comparative Example 3: 12% Indoxacarb·Chlorfluazuron Suspension Concentrate

[0042] Indoxacarb, 8%; Chlorfluazuron, 4%; Dispersant SP-SC29, 2%, GY-D07, 3%; Wetting agent 860P, 1%; Emulsifier, AEO-7P, 2%, 1601, 4%; Defoamer Sag 1522, 0.3%; Antifreeze ethylene glycol, 4%; Thickener xanthan gum, 0.1%, silica white, 1.5%; Synergistic auxiliaries Cymbopogon citratus oil 1%, mineral oil 3%; Deionized water, 66.1%.

[0043] Compared with Example 1, isomeric alcohol polyoxyethylene ether was not added in Comparative Example 3.

[0044] Comparative Example 4: 12% Indoxacarb·Chlorfluazuron Suspension Concentrate

[0045] Indoxacarb, 8%; Lufenuron, 4%; Dispersant SP-SC29, 2%, GY-D07, 3%; Wetting agent 860P, 1%; Emulsifier, AEO-7P, 2%, 1601, 4%; Defoamer Sag 1522, 0.3%; Antifreeze ethylene glycol, 4%; Thickener xanthan gum, 0.1%, silica white, 1.5%; Synergistic adjuvant citronella oil 1%, isomeric alcohol polyoxyethylene ether (C9\EO8) 3%; Deionized water, 66.1%.

[0046] Compared with Example 1, mineral oil was not added in Comparative Example 4.

[0047] Comparative Example 5: 12% Indoxacarb·Lufenuron Suspension Concentrate

[0048] Indoxacarb, 8%; Lufenuron, 4%; Dispersant SP-SC29, 2%, GY-D07, 3%; Wetting agent 860P, 1%; Emulsifier, AEO-7P, 2%, 1601, 4%; Defoamer Sag 1522, 0.3%; Antifreeze ethylene glycol, 4%; Thickener xanthan gum, 0.1%, silica white, 1.5%; Synergistic adjuvant mineral oil 3%, isomeric alcohol polyoxyethylene ether (C9\EO8) 3%; Deionized water, 64.1%.

[0049] Compared with Example 1, citronella oil was not added in Comparative Example 5.

[0050] Comparative Example 6: 12% Chlorfenapyr Suspension Concentrate

[0051] Chlorfenapyr, 12%; Dispersant SP-SC29, 2%, GY-D07, 3%; Wetting agent 860P, 1%; Emulsifier, AEO-7P, 2%, 1601, 4%; Defoamer Sag 1522, 0.3%; Antifreeze ethylene glycol, 4%; Thickener xanthan gum, 0.1%, silica white, 1.5%; Synergistic adjuvant citronella oil 1%, mineral oil 3%, isomeric alcohol polyoxyethylene ether (C9\EO8) 3%; Deionized water, 63.1%.

[0052] Compared with Example 1, Comparative Example 6 is a suspension concentrate of different active ingredient chlorfenapyr.

[0053] Comparative Example 7: 12% Chlorfenapyr Suspension Concentrate

[0054] Chlorfenapyr, 12%; Dispersant SP-SC29, 2%, GY-D07, 3%; Wetting agent 860P, 1%; Emulsifier, AEO-7P, 2%, 1601, 4%; Defoamer Sag 1522, 0.3%; Antifreeze ethylene glycol, 4%; Thickener xanthan gum, 0.1%, silica white, 1.5%; Deionized water, 70.1%.

[0055] Compared with Example 1, Comparative Example 6 is a suspension concentrate of different active ingredients, chlorfenapyr, and no synergistic adjuvant is added.

[0056] The pesticidal compositions of the above Comparative Example 1 and Comparative Examples 3-7 were prepared into corresponding dosage forms according to the preparation method of the examples.

[0057] Test

[0058] The samples prepared in the above Examples 1-3 and Comparative Examples 1-7 were stored at 0±2°C for 14 days under cold storage and at 54°C for 14 days under heat storage. The fluidity of the samples was normal, without bottom settling or flocculation, and the stability was qualified.

[0059] Determination of the interfacial properties of the liquid medicine: determination of surface tension and wetting permeability.

[0060] The permeability was measured by the wetting sedimentation method of pure cotton canvas pieces: ① Prepare 150 ml of the medicament at the use concentration in a 200 ml beaker, stir evenly, and adjust the temperature to (25±1)°C; ② Place the canvas piece on a washed wire ring, carefully place it on the leaf surface of the beaker, and start the stopwatch at the same time. Record the time when the canvas ring is completely wetted, and continue to record the time when the canvas ring just starts to settle continuously; ③ Each sample at each concentration was measured in parallel 3 times; the surface tension was measured by a surface tension meter, and the surface tension was calibrated with clear water first. The specific data are as follows:

[0061] Table 1 Interfacial measurement parameters of each medicament

[0062]

[0063] It can be seen from the above examples and comparative examples that:

[0064] (1) The surface tensions of Example 1, Example 2, Example 3, Comparative Example 4, Comparative Example 5 and Comparative Example 6 are lower, while the surface tensions of Comparative Example 1, Comparative Example 3 and Comparative Example 7 are higher, which also shows that the addition of isomeric alcohol polyoxyethylene ether can significantly reduce the surface tension of the liquid medicine.

[0065] (2) From the results of the surface tension and wetting permeability of the liquid medicine in Example 1 and Comparative Example 1, it can be seen that adding the synergistic adjuvant of the present invention to the indoxacarb·diflubenzuron preparation significantly reduces the surface tension of the liquid medicine and significantly enhances the wetting permeability of the liquid medicine.

[0066] (3) From the results of the surface tension and wetting permeability of the liquid medicine in Example 1 and Comparative Example 3, it can be seen that adding isomeric alcohol polyoxyethylene ether to the synergistic adjuvant of the present invention significantly reduces the surface tension, and at the same time, the wetting permeability is also significantly reduced, which also verifies that the surface tension of the liquid medicine also has a significant impact on the wetting permeability performance.

[0067] (4) From the results of the surface tension and wetting permeability of the liquid medicines in Example 1 and Comparative Example 4, it can be seen that adding mineral oil to the synergistic adjuvant of the present invention significantly enhances the permeability of the liquid medicine and reduces the surface tension to a certain extent.

[0068] (5) From the results of the surface tension and wetting permeability of the liquid medicines in Example 1 and Comparative Example 5, it can be seen that adding citronella oil to the synergistic adjuvant of the present invention can increase the permeability of the liquid medicine and reduce the surface tension to a certain extent.

[0069] (6) From the results of the surface tension and wetting permeability of the liquid medicines in Comparative Example 6 and Comparative Example 7, it can be seen that adding the synergistic adjuvant of the present invention to the chlorfenapyr preparation significantly reduces the surface tension of the liquid medicine and significantly enhances the wetting permeability of the liquid medicine.

[0070] Field test

[0071] Pharmacodynamic test for controlling Helicoverpa armigera

[0072] Test agents: Examples 1-3, Comparative Examples 1-7 and clear water.

[0073] Test method: The test was carried out on a farm in Xinjiang in July. The soil texture of the test plot was sandy loam with medium fertility. The test was carried out at the peak of Helicoverpa armigera egg hatching to the early peak of low-instar larvae. The area of each experimental plot was 50m 2 , and each treatment had 4 replicates; the fixed-point and fixed-plant investigation method was adopted, and the number of larvae on 25 cotton plants in each plot was investigated at fixed points. The population base of insects was investigated before applying the medicine, and the number of live insects remaining on the cotton plants was investigated 7 days and 15 days after applying the medicine, and the control effect of each treatment was calculated based on the reduction rate of the insect population.

[0074] Calculation formula:

[0075] Reduction rate of insect population = (population base of insects before medicine - population base of insects after medicine) ÷ population base of insects before medicine × 100%

[0076] Corrected control effect = (reduction rate of insect population in treatment group - reduction rate of insect population in control group) ÷ (1 - reduction rate of insect population in control group) × 100%

[0077] Table 2 Field control results of different examples on Helicoverpa armigera

[0078]

[0079]

[0080] As can be seen from Table 2, for indoxacarb·chlorfluazuron of Examples 1-3 after application, the control efficacy against Helicoverpa armigera was over 94% on the 15th day. Under the same dosage per mu, the efficacy of Examples 1-3 with the synergistic adjuvant was better than that of Comparative Examples 1-7 in controlling Helicoverpa armigera. From Example 1 and Comparative Example 1, it can be known that the synergistic adjuvant of the present invention significantly increased the control efficacy of indoxacarb·chlorfluazuron against Helicoverpa armigera. From Comparative Example 6 and Comparative Example 7, it can be known that the synergistic adjuvant of the present invention can also significantly increase the control efficacy of chlorfenapyr against Helicoverpa armigera. The synergistic adjuvant of the present invention has a more obvious synergistic effect on indoxacarb·chlorfluazuron.

[0081] Field Test on Controlling Spodoptera exigua in Cabbage

[0082] Test agents: Examples 1-3, Comparative Examples 1-7 and clear water.

[0083] Test method: The test was carried out in a vegetable base in Boxing County, Shandong Province. The soil texture of the test plot was loam with medium fertility. Spraying was carried out at the early peak stage of Spodoptera exigua. The area of each experimental plot was 20m 2 , and each treatment had 4 replicates. Mark the cabbages with Spodoptera exigua. Investigate 5 points in each plot, and investigate 2 plants at each point, and record the number of live insects; investigate the initial insect population before application, and investigate the number of remaining live insects on the test plants 7 days and 15 days after application, and calculate the control efficacy of each treatment based on the reduction rate of insect population.

[0084] The calculation formula is:

[0085] Reduction rate of insect population = (Initial insect population before application - Insect population after application) ÷ Initial insect population before application × 100%

[0086] Corrected control efficacy = (Reduction rate of insect population in treatment group - Reduction rate of insect population in control group) ÷ (1 - Reduction rate of insect population in control group) × 100%

[0087] Table 3 Field Control Results of Different Examples against Spodoptera exigua

[0088]

[0089]

[0090] As can be seen from Table 3, for indoxacarb·chlorfluazuron in Examples 1-3 after pesticide application, the control efficacy against Spodoptera exigua on cabbage at 15 days was all above 95%, and the control efficacy of the examples was significantly improved compared with that of the comparative examples; under the condition of the same dosage per mu, the pesticidal effects of Examples 1-3 with the addition of synergistic adjuvants were better than those of Comparative Examples 1-7 against Spodoptera exigua. From Example 1 and Comparative Example 1, it can be known that the synergistic adjuvant of the present invention very significantly increased the control efficacy of indoxacarb·chlorfluazuron against Spodoptera exigua. From Comparative Example 6 and Comparative Example 7, it can be known that the synergistic adjuvant of the present invention can also significantly increase the control efficacy of chlorfenapyr against Spodoptera exigua. The synergistic adjuvant of the present invention has a more obvious synergistic effect on indoxacarb·chlorfluazuron.

[0091] In summary, the present invention provides a synergistic adjuvant and an indoxacarb·chlorfluazuron liquid formulation. The synergistic adjuvant adopts a combination of three synergistic adjuvants with different action mechanisms, which can significantly reduce the surface tension of the pesticide, improve the permeability of the pesticide, and effectively improve the control efficacy of the pesticide; after adding the synergistic adjuvant to the indoxacarb·chlorfluazuron liquid formulation, the control efficacy of the indoxacarb·chlorfluazuron liquid formulation is significantly improved. The synergistic adjuvant can effectively reduce the dosage and frequency of pesticide application in the field, reduce the risk of the generation of pest and disease resistance caused by long-term use of pesticides, and is of great significance for its field integrated control.

Claims

1. A synergistic adjuvant for indoxacarb • chlorfluazuron liquid formulation, characterized in that, It includes citronella oil, mineral oil, and isomeric alcohol polyoxyethylene ether, and the weight ratio of citronella oil, mineral oil, and isomeric alcohol polyoxyethylene ether is 2 - 6:6 - 10:3 - 8; In the isomeric alcohol polyoxyethylene ether, the number of carbon atoms of the isomeric alcohol is C9 - C12, and the number of EO is 6 - 8.

2. A indoxacarb • chlorfluazuron liquid formulation, comprising an active ingredient and auxiliaries, the auxiliaries including one or more of a dispersant, a wetting agent, an emulsifier, an antifreeze, a thickener, and an antifoaming agent, characterized in that, The adjuvant further includes a synergistic adjuvant, and the synergistic adjuvant is the synergistic adjuvant described in claim 1.

3. The indoxacarb•chlorfluazuron liquid preparation according to claim 2, characterized in that, The content of the synergistic adjuvant is 5 - 8%.

4. The indoxacarb•chlorfluazuron liquid formulation according to claim 2, wherein The content of the active ingredients indoxacarb and chlorantraniliprole is 12 - 22%.

5. The indoxacarb•chlorfluazuron liquid formulation according to claim 2, characterized in that, The liquid preparation is a suspension or a microemulsion.

6. The indoxacarb•chlorfluazuron liquid formulation according to claim 2, wherein The dispersant is one or more of polycarboxylate dispersants and high - molecular amphiphilic anionic - nonionic surfactants.

7. The indoxacarb•chlorfluazuron liquid formulation according to claim 2, wherein The wetting agent is a modified alkylphenol polyoxyethylene ether - type wetting agent.

8. The indoxacarb•chlorfluazuron liquid formulation according to claim 2, characterized in that, The defoaming agent is a polysiloxane - type defoaming agent; the thickener is one or both of xanthan gum and silica white, and the antifreeze is ethylene glycol.

9. The indoxacarb and lufenuron liquid formulation according to claim 2, wherein The emulsifier is one or more of fatty alcohol polyoxyethylene ether phosphate and polyoxypropylene - polyoxyethylene block polymer.

Images