Biosecretor analyzer

The automated testing process of the biological secretion analyzer has solved the problems of low accuracy and efficiency in vaginal cell sample testing, achieving efficient and accurate diagnosis of vaginal diseases.

CN116698555BActive Publication Date: 2026-03-20HUNAN PINXIN BIOLOGICAL ENG CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-05-11
Publication Date
2026-03-20

AI Technical Summary

Technical Problem

In existing technologies, vaginal cell sample fluid testing suffers from low accuracy, efficiency, and flexibility. Manual testing is inefficient, prone to inconsistencies, and incurring high labor costs.

Method used

A biological secretion analyzer was designed, comprising a test tube rack assembly, a slide box assembly, a slide delivery assembly, a barcode scanning assembly, a sampling assembly, a heating assembly, a staining assembly, a mounting assembly, and an analysis assembly. This analyzer enables automated detection of vaginal cell sample fluid. The barcode scanning assembly identifies test tube information, the sampling assembly extracts the sample fluid, and after heating, staining, and mounting, the analysis assembly performs the analysis.

Benefits of technology

It enables automated testing of vaginal cell samples, improving the accuracy, efficiency, and flexibility of testing, while reducing errors and labor costs associated with manual intervention.

✦ Generated by Eureka AI based on patent content.

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    Figure CN116698555B_ABST
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Abstract

The biological secretion analyzer provided by the application comprises a base, and the base is provided with a test tube rack assembly, a glass slide box assembly, a glass slide conveying assembly, a code scanning assembly, a sampling assembly, a heating assembly, a staining assembly, a slide sealing assembly and an analysis assembly. The biological secretion analyzer provided by the application can compactly, efficiently and stably sample sample cells, realize code reading, staining, slide sealing, scanning, AI analysis and diagnosis and other intelligent pathological detection, has a pipeline structure layout and compact structure, an operator can take products up and down at the front of the equipment, operation is convenient, and multi-point online feedback is high in intelligent degree.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a biological secretion analyzer. BACKGROUND

[0002] With the gradual improvement of health awareness, the degree of attention to health, and the complex influence of environment and many other aspects, female diseases have become more common, and vaginal diseases are common diseases among female diseases. Vaginal diseases are important risk factors for diseases such as infertility, urinary tract infection, ectopic pregnancy, uterine cavity infection, salpingitis, endometritis, and are the main cause of pregnancy complications such as amniotic fluid infection, neonatal infection, and premature delivery in obstetrics.

[0003] The analysis of vaginal cell sample liquid needs to detect the pH value, anaerobic bacteria and facultative anaerobic bacteria infection index, white blood cell index, beneficial bacteria lactobacillus quantity, Candida albicans and trichomonas infection index, proline aminopeptidase activity, glucuronidase activity and other related indicators of the vaginal cell sample liquid, which is beneficial to the early treatment of vaginal diseases and the reduction of the incidence of complications, and reduces the risk of related diseases. It has great social value for the health of women's bodies and the improvement of fertility level. At present, the clinical vaginal cell sample liquid is detected by artificial direct or indirect detection method to distinguish various indicators. Due to the difference between different doctors, visual fatigue and inconsistent results, even misjudgment, the incubation time is too short or too long, which affects the detection effect. In addition, artificial detection is low in efficiency, easy to cause slow result and sample accumulation, and high in labor cost. The accuracy, efficiency and flexibility of the detection result are relatively low. SUMMARY

[0004] In view of the above problems existing in the prior art, the biological secretion analyzer provided by the present application can realize automatic detection of the vaginal cell sample liquid, greatly improving the accuracy, efficiency and flexibility of the vaginal cell sample liquid detection.

[0005] To achieve the above application purposes, the technical solutions adopted by the present application are as follows:

[0006] The biological secretion analyzer comprises a base, and the base is provided with a test tube rack assembly, a glass slide box assembly, a glass slide conveying assembly, a code scanning assembly, a sampling assembly, a heating assembly, a staining assembly, a slide sealing assembly and an analysis assembly,

[0007] The test tube rack assembly comprises a test tube containing a cell sample liquid;

[0008] The glass slide box assembly comprises a glass slide;

[0009] The glass slide conveying assembly is used to move the glass slides from the glass slide box assembly one by one from one side of the base to the other side;

[0010] The code scanning component is used to identify the barcode on the test tube;

[0011] The sampling component is used to extract the cell sample liquid from the inside of the test tube and drop it onto the surface of the slide on the slide conveying component;

[0012] The heating component is used to heat the cell sample liquid on the surface of the slide on the slide conveying component;

[0013] The staining component is used to stain the cell sample liquid on the surface of the slide after heating;

[0014] The slide sealing component is used to seal the slide after staining;

[0015] The analysis component is used to analyze the cell sample liquid after sealing.

[0016] In one embodiment, the test tube rack component includes a test tube rack, a material rack, and a test tube rack driving mechanism, the test tube is arranged on the test tube rack, the material rack is arranged on the base, the material rack is provided with a material tray, the test tube rack is arranged on the material tray, and the test tube rack driving mechanism is arranged on the material rack. The test tube rack driving mechanism is used to drive the test tube rack placed on the right end of the material tray to the left end of the material tray.

[0017] In one embodiment, the code scanning component includes a scanner support arranged on the base, the scanner support is provided with a scanner for scanning the barcode on the surface of the test tube, and the scanner support is located on one side of the middle position of the material tray.

[0018] The scanner support is also provided with a test tube rotation driving wheel and a test tube rotation auxiliary wheel, the test tube rotation driving wheel is arranged above the scanner, the two test tube rotation auxiliary wheels can be inserted into the gap between the test tubes from the rear side of the test tubes and clamp the test tubes, the test tube rotation driving wheel is located on the front side of the test tubes, and the test tube rotation driving wheel is used to drive the test tubes to rotate.

[0019] In one embodiment, the slide box component includes a slide box support, a slide box, and a slide located inside the slide box, the slide box support is arranged on the base, the slide box is arranged on the slide box support,

[0020] The slide conveying assembly comprises a conveying support arranged on the base, a conveying bottom plate arranged on the conveying support, a slide paw arranged movably on the conveying bottom plate, two conveying grooves arranged side by side in front of and behind the conveying bottom plate, and a gap arranged between the two conveying grooves,

[0021] The bottom plate of the slide box is divided into two parts by a first through hole arranged on the bottom plate, the lower edges of the two opposite side walls of the slide box are respectively provided with first notches, the first notches are arranged opposite to the first through hole, the width of the first notch arranged on the right side wall of the slide box is smaller than the width of the slide, the width of the first notch arranged on the left side wall of the slide box is larger than the width of the slide, and the height of the first notch is larger than the thickness of the slide,

[0022] The slide box is arranged at the right end of the conveying groove, the center line of the gap between the first through hole and the two conveying grooves is arranged on the same line, and the upper end of the slide paw is inserted into a channel formed by the first through hole and the gap between the two conveying grooves.

[0023] In one embodiment, the sampling assembly comprises a sampling support, a sampling arm, a sampling tube, a sampling tube cleaning system and a sampling suction power system,

[0024] The sampling support is arranged on the rear side of the conveying groove, the sampling arm is arranged movably along the Y-axis and the Z-axis on the sampling support, the sampling tube is arranged longitudinally on the sampling arm, the upper end of the sampling tube is communicated with the sampling tube cleaning system and the sampling suction power system through a hose and a reversing valve respectively,

[0025] The sampling tube cleaning system provides cleaning water to clean the inside of the sampling tube, and the sampling suction power system provides suction and inspiration for the sampling tube to realize suction or discharge of the cell sample liquid.

[0026] In one embodiment, the heating assembly comprises a heating support and a heating fan, the heating support is arranged on the base and located on the left side of the sampling support, and the heating fan is arranged on the heating support and located above the conveying groove.

[0027] In one embodiment, the staining assembly comprises a staining support, a staining arm, a reagent tube, a reagent bottle, a reagent tube cleaning system and a staining suction power system,

[0028] The dyeing support is arranged on the base and located at the left side of the sampling support, the dyeing arm is arranged on the dyeing support and can move along the Y-axis and Z-axis directions, a plurality of the reagent tubes are arranged on the dyeing arm in the longitudinal direction, the upper ends of the plurality of the reagent tubes are respectively communicated with the reagent tube cleaning system and the dyeing suction power system through the hose and the reversing valve, the reagent tube cleaning system provides cleaning water to clean the inside of the reagent tube, and the dyeing suction power system provides suction and suction force for the reagent tube to realize reagent tube suction or reagent discharge,

[0029] The reagent bottle is located above the conveying groove and at the left side of the heating fan, and the center lines of the reagent bottle and the plurality of reagent tubes are located on the same straight line along the Y-axis direction.

[0030] In one of the embodiments, the cover glass assembly includes a cover glass box, a cover glass box support, a cover glass adhering body, a suction arm support, a suction nozzle, and a suction nozzle power system, the cover glass box is arranged in the cover glass box,

[0031] The cover glass support is arranged at the rear side of the conveying groove and at the left side of the dyeing support, the cover glass box is arranged on the cover glass support and can move along the Y-axis direction,

[0032] The suction arm support is arranged on the base, the suction arm is arranged on the suction arm support and can move along the Z-axis direction, and the suction arm is located above the conveying groove, the suction nozzle is arranged on the lower end surface of the suction arm, the upper end of the suction nozzle is communicated with the suction nozzle power system through the hose, and the suction nozzle power system provides suction and suction force for the suction nozzle to realize suction nozzle suction or cover glass loosening,

[0033] The suction nozzle and the center line of the cover glass box are located on the same straight line along the Y-axis direction.

[0034] In one of the embodiments, the analysis assembly includes a camera support, a camera, a slide position adjustment platform, a fluorescence module, and a lens,

[0035] The camera support is arranged on the base and located at the left side of the cover glass box support, the camera is arranged on the camera support and can move along the Z-axis direction, the fluorescence module is arranged on the camera support and can move along the X-axis direction, and the fluorescence module is located below the camera, the lens is arranged on the camera support and located below the fluorescence module,

[0036] The slide position adjusting platform is movably arranged on the camera support in the X-axis and Y-axis directions, is located below the lens, at the left end of the conveying groove and above the conveying bottom plate, and the upper surface of the slide position adjusting platform is provided with a slide groove, the right end of the slide groove is in abutment with the left end of the conveying groove, a second notch is arranged on the bottom wall of the right end of the slide groove, the slide groove, the second notch and the center line of the first through hole are located on the same straight line in the left-right direction, and the camera, the fluorescence module and the lens are located on the same plane in the vertical direction.

[0037] In one of the embodiments, a slide recycling box is further included, and the slide recycling box is arranged on the base and located below the left end of the slide position adjusting platform.

[0038] Compared with the prior art, the biological secretion analyzer provided by the application can transport the test tube containing the cell sample liquid to a suitable position through the test tube rack assembly, push out the slides in the slide conveying assembly one by one to the slide conveying assembly, identify the patient information corresponding to the detection sample in the two-dimensional code on the surface of the test tube through the code scanning assembly and transport the information to the system of the analyzer, then suck the cell sample liquid droplets from the test tube to the slide on the slide conveying assembly through the sampling assembly, then sequentially pass through the heating assembly, the staining assembly and the slide sealing assembly to make the cell sample liquid to be detected into a slide sample, then take a picture of the slide sample through the analysis assembly, upload the image to the system of the analyzer for corresponding image processing, analysis and diagnosis, and finally automatically generate a diagnosis report. The biological secretion analyzer provided by the application can realize automatic detection of the vaginal cell sample liquid and greatly improve the accuracy, efficiency and flexibility of the vaginal cell sample liquid detection. BRIEF DESCRIPTION OF DRAWINGS

[0039] Figure 1 It is a first partial three-dimensional structure schematic view of the application;

[0040] Figure 2 It is a first partial three-dimensional structure schematic view of the test tube rack driving mechanism in the application;

[0041] Figure 3 It is a second partial three-dimensional structure schematic view of the application;

[0042] Figure 4 It is a partial three-dimensional structure schematic view of the second test tube rack driving mechanism and the code scanning assembly in the application;

[0043] Figure 5 It is a partial three-dimensional structure schematic view of the third test tube rack driving mechanism in the application;

[0044] Figure 6This is a partial three-dimensional structural diagram of the glass slide delivery assembly in this invention;

[0045] Figure 7 This is a partial three-dimensional structural diagram of the sampling component in this invention;

[0046] Figure 8 This is a partial three-dimensional structural diagram of the staining component in this invention;

[0047] Figure 9 This is a partial three-dimensional structural diagram of the sealing assembly in this invention;

[0048] Figure 10 This is a first partial three-dimensional structural schematic diagram of the analysis component in this invention;

[0049] Figure 11 This is a schematic diagram of the second partial three-dimensional structure of the analysis component in this invention. Detailed Implementation

[0050] In the description of this invention, it should be understood that the terms "center", "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "axial", "radial", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this invention and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this invention.

[0051] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly specified.

[0052] In this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0053] In the present disclosure, unless specifically stated and limited otherwise, a first feature is "on" or "under" a second feature can mean that the first and second features are in direct contact, or the first and second features are in indirect contact with a medium in between. Also, the first feature "over", "above" and "on top of" the second feature can mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is horizontally higher than the second feature. The first feature "under", "below" and "underneath" the second feature can mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is horizontally lower than the second feature.

[0054] In the description of the present disclosure, the description of the terms "one embodiment", "some embodiments", "an example", "a specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present disclosure. In the present disclosure, the illustrative description of the above terms does not necessarily refer to the same embodiment or example. Also, the specific features, structures, materials or characteristics described can be combined in any suitable manner in one or more embodiments or examples. In addition, the person skilled in the art can combine and combine the different embodiments or examples described in the present disclosure and the features of the different embodiments or examples without contradiction.

[0055] As shown in Figures 1-11

[0056] The biological secretion analyzer comprises a base 1, on which a test tube rack assembly, a slide box assembly, a slide conveying assembly, a code scanning assembly, a sampling assembly, a heating assembly, a staining assembly, a mounting assembly and an analyzing assembly are arranged,

[0057] The test tube rack assembly comprises a test tube 2 containing a cell sample liquid;

[0058] The slide box assembly comprises a slide 3;

[0059] The slide conveying assembly is used to move the slide 3 from the slide box assembly one by one from one side of the base 1 to the other side;

[0060] The code scanning assembly is used to identify the bar code on the test tube 2;

[0061] The sampling assembly is used to extract the cell sample liquid from the inside of the test tube 2 and drop it onto the surface of the slide 3 located on the slide conveying assembly;

[0062] The heating assembly is used to heat the cell sample liquid on the surface of the slide 3 located on the slide conveying assembly;

[0063] The staining assembly is used to perform staining treatment on the cell sample liquid on the surface of the slide 3 after heating; ​

[0064] The sealing assembly is used for sealing treatment on the slide 3 after dyeing treatment;

[0065] The analysis assembly is used for analysis treatment on the cell sample liquid after sealing treatment.

[0066] The biological secretion analyzer provided by the application transports the test tube 2 containing the cell sample liquid to the position close to the slide conveying assembly through the test tube rack assembly, the slide conveying assembly pushes out the slide 3 in the slide box assembly one by one and sends the slide 3 to the slide conveying assembly, meanwhile, the patient information corresponding to the detection sample in the two-dimensional code on the surface of the test tube 2 is recognized by the code scanning assembly and is sent to the system of the analyzer, then the cell sample liquid is sucked from the test tube 2 by the sampling assembly and is dropped on the slide 3 on the slide conveying assembly, then the cell sample liquid to be detected is made into a slide sample through the heating assembly, the dyeing assembly and the sealing assembly in turn, then the slide sample is photographed by the analysis assembly, after the image is taken, the image is uploaded to the system of the analyzer for corresponding image processing, analysis and diagnosis, and finally a diagnosis report is automatically generated.

[0067] In one of the embodiments, the test tube rack assembly comprises a test tube rack 4, a material rack 5 and a test tube rack driving mechanism, the test tube 2 is arranged on the test tube rack 4, the material rack 5 is arranged on the base 1, the material rack 1 is provided with a material supporting plate 6, the test tube rack 4 is arranged on the material supporting plate 6, and the test tube rack driving mechanism is arranged on the material rack 5 and is used for driving the test tube rack 4 placed on the right end of the material supporting plate 6 to the left end of the material supporting plate 6;

[0068] Specifically, the test tube rack driving mechanism comprises a first test tube rack driving mechanism, a second test tube rack driving mechanism and a third test tube rack driving mechanism,

[0069] The first test tube rack driving mechanism comprises a first sliding rail 7 arranged on the bottom plate 1 in the front-rear direction of the bottom plate 1, a first sliding block 8 arranged on the first sliding rail 7, a connecting plate 9 arranged on the first sliding block 8, a first transmission rod 10 arranged on the connecting plate 9, transmission blocks 11 rotatably arranged at the left and right ends of the first transmission rod 10, test tube rack clamping blocks 12 arranged on the upper surfaces of the transmission blocks 11, and the two test tube rack clamping blocks 12 being respectively located at the two ends of the test tube rack 4 placed on the material supporting plate 6,

[0070] The lower surfaces of the two ends of the first transmission rod 10 and the lower surfaces of the transmission blocks 11 are respectively provided with first spring pins 13, and the first spring pins 13 on the transmission blocks 11 and the first spring pins 13 on the first transmission rod 10 adjacent to the transmission blocks 11 are provided with first springs 14 therebetween,

[0071] The right side of the first sliding block 8 is provided with a first tooth block 15, the first tooth block 15 is provided with a first pressing block 16, the first pressing block 16 and the first tooth block 15 are provided with a first toothed belt 17, the first tooth block 15 is engaged with the first toothed belt 17, the bottom plate 1 at the front end of the first sliding rail 7 is rotatably provided with a first toothed pulley through a support, the bottom plate 1 at the rear end is provided with a first motor 19, the main shaft of the first motor 19 is provided with a second toothed pulley, and the first toothed belt 17 is sleeved on the first toothed pulley and the second toothed pulley;

[0072] Through the above design structure, it can be known that the rotation of the main shaft of the first motor 19 drives the first sliding block 8 to move forward and backward along the first sliding rail 7 through the first toothed belt 17, the first tooth block 15 and the first pressing block 16, thereby driving the connecting plate 9, the first transmission rod 10, the transmission block 11 and the test tube rack clamping block 12 to move forward and backward as a whole,

[0073] Therefore, first, a plurality of test tube racks 4 on which test tubes 2 are placed are placed side by side in front and back directions on the right end of the material supporting plate 6, at this time, the two test tube rack clamping blocks 12 are located behind the plurality of test tube racks 4, when it is needed to push the test tube rack 4 located in front of the two test tube rack clamping blocks 12, the first motor 19 drives the two test tube rack clamping blocks 12 to move forward, because the two test tube rack clamping blocks 12 are respectively rotatably connected with the two ends of the first transmission rod 10 through bearings, therefore, when the two test tube rack clamping blocks 12 encounter resistance, they will respectively deflect outward to open to realize moving from the front of the rear test tube rack 4 to the front of the front test tube rack 4, at this time, the two test tube rack clamping blocks 12 are reset under the action of the first spring 14, then the test tube rack 4 located behind the two test tube rack clamping blocks 12 is driven by the first motor 19 and the two test tube rack clamping blocks 12 to move backward until it touches the contact switch located at the right end of the material supporting plate 6, and the like can be sequentially realized, which can realize pushing the test tube racks 4 on the right end of the material supporting plate 6 one by one backward, after the test tube racks 4 on the right end of the material supporting plate 6 are all moved, the operator can add the test tube racks 4 on which test tubes 2 are placed to the material supporting plate 6;

[0074] Further, the second test tube rack driving mechanism includes a second sliding rail 22 provided on the base 1 and arranged in the left-right direction, a second sliding block 23 provided on the second sliding rail 22, a second tooth block 30 provided on the second sliding block 23, a first transmission plate 24 provided on the second tooth block 30, a test tube rack pawl 25 rotatably provided on the back of the first transmission plate 24, a first limiting block 26 provided on the first transmission plate 24 at the right side of the test tube rack pawl 25, a second spring pin 27 further provided on the back of the first transmission plate 24, the second spring pin 27 being located at the left side of the test tube rack pawl 25, a second spring 28 being hooked to the second spring pin 27, and the other end of the second spring 28 being hooked to the lower end of the test tube rack pawl 25,

[0075] The second tooth block 30 is provided with a second pressing block 29, and the second pressing block 29 and the second tooth block 30 are provided with a second toothed belt 31. The second tooth block 30 is engaged with the second toothed belt 31. The base 1 at the right end of the second slide rail 22 is rotatably provided with a third toothed pulley through a support. The base 1 at the left end is provided with a second motor 33. The main shaft of the second motor 33 is provided with a fourth toothed pulley. The second toothed belt 31 is sleeved on the third toothed pulley and the fourth toothed pulley.

[0076] Through the above design structure, it can be known that the rotation of the main shaft of the second motor 33 drives the second sliding block 23 to move left and right along the second slide rail 22 through the second toothed belt 31, the second tooth block 30 and the second pressing block 29, thereby driving the first transmission plate 24 and the test tube rack pawl 25 to move left and right as a whole.

[0077] Therefore, when the test tube rack 4 is driven to the rear edge of the right end of the material supporting plate 6 by the first motor 19, the second motor 33 drives the test tube rack pawl 25 to move right at this time. Because the test tube rack pawl 25 is connected with the first transmission plate 24 through a bearing to realize left and right deflection, at this time, the upper end of the test tube rack pawl 25 is inclined to the left and further passes through the frame of the lower end of the test tube rack 4, until the upper end of the test tube rack pawl 25 moves to the groove at the bottom of the test tube rack 4, the test tube rack pawl 25 will restore to the vertical state under the action of the second spring 28, so that the upper end of the test tube rack pawl 25 is inserted into the groove at the bottom of the test tube rack 4, and then the second motor 33 drives the test tube rack pawl 25 to move left. The upper end of the test tube rack pawl 25 will not be deflected to the right under the block of the first limiting block 26, so that the test tube rack 4 can be driven to move left until it touches the contact switch at the left edge of the left end of the material supporting plate 6. In this way, the test tube rack 4 at the rear edge of the right end of the material supporting plate 6 can be moved to the rear edge of the left end of the material supporting plate 6 week by week.

[0078] Preferably, the right upper corner of the test tube rack pawl 25 is provided with a round corner, so that when the test tube rack pawl 25 moves right, it can better pass through the lower end of the test tube rack 4 and move more smoothly.

[0079] Through the above structural design can be known: test tube rack prongs 25 to the left when the first limit block 26 under the action of the vertical state, in order to better promote the test tube rack 4 to the left, when the test tube rack prongs 25 to the material tray 6 left end touch located on the left end of the material tray 6 limit switch, at this time the test tube rack 4 has been pushed to the left end of the material tray 6, therefore, the test tube rack prongs 25 will move to the right to push the next test tube rack 4, at this time, because the test tube rack prongs 25 and the first transmission plate 24 between the bearing can be realized by rotating connection, in the test tube rack prongs 25 to the right in the process of moving, the upper end of the test tube rack prongs 25 will be left deflection in order to be able to smoothly through the lower end of the test tube rack 4, when the test tube rack prongs 25 to the next test tube rack 4 below, because each test tube rack 4 lower end is respectively provided with a groove, the test tube rack prongs 25 to the test tube rack 4 below, under the action of the second spring 28, will automatically reset to the vertical state, so that the upper end of the test tube rack prongs 25 will be inserted into the groove below the test tube rack 4, in turn through the test tube rack prongs 25 to promote the test tube rack 4 to the left;

[0080] Further, the third test tube rack driving mechanism includes a first support plate 35 arranged on the base 1, the first support plate 35 is provided with a third motor 36, the main shaft of the third motor 36 is screwed with a second transmission rod 37 arranged along the left-right direction, the two ends of the second transmission rod 37 are respectively provided with guide rods 38, the rear ends of the two guide rods 38 respectively penetrate the first support plate 35 rearward, and the front end of the second transmission rod 37 is provided with a test tube rack pushing plate 39;

[0081] Through the above design structure can be known: when the second motor 33 drives the test tube rack 4 to move to the left until it touches the contact switch located on the left edge of the left end of the material tray 6, at this time, the main shaft of the third motor 36 rotates to drive the test tube rack pushing plate 39 to move forward through the second transmission rod 37 and the two guide rods 38, and in turn pushes the test tube rack 4 located in front of the test tube rack pushing plate 39 forward until the test tube rack 4 touches the contact switch located on the front edge of the left end of the material tray 6. In this way, the test tube rack 4 located on the rear edge of the left end of the material tray 6 can be moved to the front edge of the left end of the material tray 6 one by one.

[0082] As described above, through the first test tube rack driving mechanism, the second test tube rack driving mechanism and the third test tube rack driving mechanism, the test tube rack 4 placed on the material tray 6 can be moved from the right end of the material tray 6 to the front edge of the material tray 6 and then to the left end of the material tray 6 one by one.

[0083] In the embodiment, the code scanning assembly includes a scanner support 40 arranged on the base 1, and a scanner 41 for scanning the bar code on the surface of the test tube is arranged on the scanner support 40. The scanner support 40 is arranged in a groove on the front side of the material tray 6 at the middle position of the material tray 6,

[0084] The scanner support 40 is further provided with a test tube rotating driving wheel 34 and test tube rotating auxiliary wheels 42. The test tube rotating driving wheel 34 is arranged above the scanner 41. The two test tube rotating auxiliary wheels 42 can be inserted into the gap between the test tubes 2 from the rear side of the test tubes 2 and clamp the test tubes 2. The test tube rotating driving wheel 34 is located at the front side of the test tubes 2 and is used to drive the test tubes 2 to rotate.

[0085] The top end of the scanner support 40 is provided with a fourth motor 43. The main shaft of the fourth motor 43 is arranged vertically downward. The test tube rotating driving wheel 34 is arranged on the main shaft of the fourth motor 43.

[0086] The top end of the scanner support 40 is further provided with a third sliding rail 44 arranged in the front-rear direction. The third sliding rail 44 is provided with a third sliding block 45. The third sliding block 45 is provided with a connecting plate 46. The connecting plate 46 is provided with two test tube rotating auxiliary wheels 42 rotatably arranged side by side on the front edge through a rotating shaft.

[0087] The third sliding block 45 is further provided with a driving block. The top of the scanner support 40 at the front end of the third sliding rail 44 is provided with a fifth motor 48. The main shaft of the fifth motor 48 penetrates the driving block and is screwed with the driving block.

[0088] In this way, when the test tubes 2 move to the left with the test tube rack 4, they temporarily stop moving when they come to the front of the scanner 41. At this time, if the bar code on the test tube 2 is directly opposite the scanner 41, the scanner 41 can directly scan the bar code on the test tube 2. If the bar code on the test tube 2 is not directly opposite the scanner 41, the scanner 41 cannot scan the bar code on the test tube 2. At this time, the fifth motor 48 rotates to drive the two test tube rotating auxiliary wheels 42 on the connecting plate 46 to move forward to drive the test tubes 2 to move forward until the test tubes 2 are in contact with the test tube rotating driving wheel 34 and the two test tube rotating auxiliary wheels 42 at the same time. Then the fourth motor 43 rotates to drive the test tubes 2 to rotate by a certain angle through the test tube rotating driving wheel 43, so that the bar code on the test tube 2 can be recognized by the scanner 41. If the inductor on the scanner support 40 senses the inductive plate on the main shaft of the fourth motor 43 twice in succession and the scanner 41 still cannot scan the bar code on the test tube 2, it means that the bar code on the test tube 2 has a problem or falls off. Therefore, the subsequent sampling step of the device will not be carried out on the test tube 2, so as to avoid the phenomenon that the subsequent detection result and the patient information do not match.

[0089] In the embodiment, the slide box assembly comprises a slide box support 49, a slide box 50 and slides 3 inside the slide box 50, the slide box support 49 is arranged on the base 1, the slide box 50 is arranged on the slide box support 49,

[0090] The slide conveying assembly comprises a conveying support 51, the conveying support 51 is arranged on the base 1, a conveying bottom plate 52 is arranged on the conveying support 51, a slide pushing claw 53 is movably arranged on the conveying bottom plate 52, two conveying grooves 54 are arranged in front of and behind the conveying bottom plate 52, and a gap is arranged between the two conveying grooves 54,

[0091] A first through hole is arranged on the bottom plate of the slide box 50 to divide the slide box 50 into two parts, first notches 56 are arranged on the lower edges of the opposite two side walls of the slide box 50, the first notches 56 are arranged opposite to the first through hole, the height of the first notches 56 is greater than the thickness of the slide 3, the width of the first notch 56 on the right side wall of the slide box 50 is less than the width of the slide 3, and the width of the first notch 56 on the left side wall of the slide box 50 is greater than the width of the slide 3,

[0092] The slide box 50 is located at the right end of the conveying groove 54, and the center line of the gap between the first through hole and the two conveying grooves 54 is located on the same straight line, and the upper end of the slide pushing claw 53 is inserted into the channel formed by the first through hole and the gap between the two conveying grooves 54;

[0093] Specifically, a fourth sliding rail 57 is arranged on the conveying bottom plate 52 in the left-right direction, a fourth sliding block 58 is arranged on the fourth sliding rail 57, a second transmission plate 59 is arranged on the fourth sliding block 58, the slide pushing claw 53 is rotatably arranged on the back of the second transmission plate 59, a second limiting block is arranged on the right side of the second transmission plate 59, a third spring pin is further arranged on the back of the second transmission plate 59, the third spring pin is located on the left side of the slide pushing claw 53, a third spring 62 is hooked to the third spring pin, and the other end of the third spring 62 is hooked to the lower end of the slide pushing claw 53,

[0094] A third tooth block is arranged on the fourth sliding block 58, a third pressing block is arranged on the third tooth block, a third toothed belt 65 is arranged between the third pressing block and the third tooth block, the third tooth block is engaged with the third toothed belt 65, a fifth toothed belt wheel is rotatably arranged on the conveying bottom plate 52 at the left end of the fourth sliding rail 57, a sixth motor is arranged below the conveying bottom plate 52 at the right end, the main shaft of the sixth motor penetrates the conveying bottom plate 52 upwardly and is provided with a sixth toothed belt wheel, and the third toothed belt 65 is sleeved on the fifth toothed belt wheel and the sixth toothed belt wheel;

[0095] Through the above design structure can be known: the sixth motor spindle rotation through the third toothed belt 65, the third pressing block and the third tooth block to drive the fourth slider 58 along the fourth slide rail 57 left and right movement, in turn realize the drive second transmission plate 59 and the slide glass claw 53 whole together left and right movement,

[0096] Therefore, the sixth motor drive slide glass claw 53 from the fourth slide rail 57 most right end to the left side, because the first through hole and the gap between the two gap 54 center line is located in the same straight line, and the upper end of the slide glass claw 53 is inserted in the gap between the first through hole and the two gap 54 formed by the channel, therefore, the upper end of the slide glass claw 53 in through the first through hole on the slide glass box 50 bottom plate, the slide glass claw 53 will be located in the slide glass box 50 inside the lowermost one slide glass 3 push out of the slide glass box 50 and push to be arranged in front of and behind the two gap 54 between, with the continuous rotation of the sixth motor, so as to realize the purpose of the slide glass 3 from the base 1 right end to the left end;

[0097] On the other hand, because the height of the first gap 56 is greater than the thickness of the slide glass 3, and the width of the first gap 56 on the right side wall of the slide glass box 50 is less than the width of the slide glass 3, the width of the first gap 56 on the left side wall of the slide glass box 50 is greater than the width of the slide glass 3, and the slide glass claw 53 and the second transmission plate 59 are connected by bearings to realize left and right deflection, at this time, the slide glass claw 53 will be skewed to the left when passing under the slide glass box 50 from left to right, and the upper end of the slide glass claw 53 will be skewed to the left and then pass under the slide glass box 50, until the upper end of the slide glass claw 53 moves to the outside of the right end of the slide glass box 50 and is sensed by the corresponding sensor, the slide glass claw 53 will return to the vertical state under the action of the third spring 62, and then move to the left under the drive of the sixth motor, the upper end of the slide glass claw 53 will not be skewed to the right under the block of the second limiting block, so as to realize the drive of the slide glass 3 to the left until the left end of the gap 54, so as to realize the movement of the slide glass 3 from the right end of the gap 54 to the left end of the gap 54 one by one;

[0098] Preferably, the right upper corner of the slide glass claw 53 is rounded, so that the slide glass claw 53 can better cross the lower end of the slide glass 3 when moving to the right, and the movement is more smooth;

[0099] Through the above structural design, when the slide pushing claw 53 moves to the left, it keeps a vertical state under the action of the second limiting block, so as to better push the slide 3 to move to the left. When the slide pushing claw 53 moves to the left end of the material conveying groove 54 and is sensed by the corresponding sensor, the slide pushing claw 53 will move to the right to push the next slide 3. At this time, because the slide pushing claw 53 is rotatably connected to the second transmission plate 59 through a bearing, the upper end of the slide pushing claw 53 will deflect to the left during the movement of the slide pushing claw 53 to the right, so that it can smoothly pass through the lower end of the slide box 50. When the upper end of the slide pushing claw 53 moves to the outside of the right end of the slide box 50, it will automatically return to a vertical state under the action of the third spring 62. In this way, the slide pushing claw 53 can push the next slide 3 to move to the left, and the slides 3 in the slide box 50 can be moved one by one from the right end of the conveying groove 54 to the left end of the conveying groove 54.

[0100] In the embodiment, the sampling assembly comprises a sampling support 67, a sampling arm 68, a sampling tube 69, a sampling tube cleaning system and a sampling suction power system.

[0101] The sampling support 67 is arranged at the rear side of the conveying groove 54, the sampling arm 68 is arranged on the sampling support 67 and can move along the Y axis and the Z axis, and the sampling tube 69 is arranged vertically on the sampling arm 68. The upper end of the sampling tube 69 is in communication with the sampling tube cleaning system and the sampling suction power system through a hose and a reversing valve respectively.

[0102] The sampling tube cleaning system provides cleaning water to clean the inside of the sampling tube 69, and the sampling suction power system provides suction and suction power for the sampling tube 69 to realize the suction or discharge of the cell sample liquid.

[0103] Specifically, the sampling support 67 is provided with a sliding rail along the Y axis, a sliding block is arranged on the sliding rail, a tooth block is arranged on the sliding block, a pressing block is arranged on the tooth block, a toothed belt is arranged between the pressing block and the tooth block, and the tooth block and the toothed belt are in meshing relationship with each other. The sampling support 67 at the front end of the sliding rail is rotatably provided with a toothed belt pulley through a support, the right side of the sampling support 67 at the rear end is provided with a seventh motor 70, the main shaft of the seventh motor 70 penetrates the sampling support 67 to the left and is provided with a toothed belt pulley, the toothed belt is sleeved on the toothed belt pulleys at both ends of the sliding rail, and a sampling arm mounting plate 71 is arranged on the sliding block.

[0104] The sampling arm mounting plate 71 is provided with a sliding rail in the Z-axis direction, a sliding block is arranged on the sliding rail, a tooth block is arranged on the sliding block, a pressing block is arranged on the tooth block, the sampling arm 68 is arranged on the sliding block, a toothed belt is arranged between the pressing block and the tooth block, the tooth block and the toothed belt are in meshing connection with each other, the toothed belt wheel is rotatably arranged on the sampling arm mounting plate 71 at the lower end of the sliding rail through a support, the eighth motor 72 is arranged on the right side of the sampling arm mounting plate 71 at the upper end, the main shaft of the eighth motor 72 penetrates the sampling arm mounting plate 71 to the left and is provided with a toothed belt wheel, and the toothed belt is sleeved on the toothed belt wheels at the two ends of the sliding rail.

[0105] It can be known from the above design structure that the rotation of the main shaft of the seventh motor 70 drives the sampling arm mounting plate 71 to move forward and backward through the toothed belt, the pressing block and the tooth block, the rotation of the main shaft of the eighth motor 72 drives the sampling arm 68 to move up and down through the toothed belt, the pressing block and the tooth block, and then the sampling tube 69 can move along the Y-axis and the Z-axis directions on the sampling support 67.

[0106] Further, the sampling tube cleaning system comprises a water pump, a clean water tank and a water pipe, the sampling suction power system comprises an air pump and an air pipe, the water inlet end of the water pump is communicated with the clean water tank through the water pipe, the other end is communicated with one end of a three-way electromagnetic reversing valve through the water pipe, the air pump is communicated with the other end of the three-way electromagnetic reversing valve through the air pipe, and finally the other end of the three-way electromagnetic reversing valve is communicated with the upper end of the sampling tube 69 through a pipeline. A sewage recovery tank is further arranged on the left side of the sampling support 67 at the rear side of the conveying groove 54. When sampling is needed, the sampling tube 69 is first moved above the sewage recovery tank, then the water pump draws clean water from the clean water tank to flush the inner wall of the sampling tube 69, then the sampling tube 69 is driven by the seventh motor 70 and the eighth motor 72 to be above one of the test tubes 2 on the front side of the conveying groove 54, at this time the scanner 41 synchronously scans the two-dimensional code information on the test tube 2, after successful scanning, the sampling tube 69 is inserted into the test tube 2, the three-way electromagnetic reversing valve is reversed, at this time the air pump is communicated with the sampling tube 69, so that the air pump sucks the cell sample liquid from the test tube 2, then the sampling tube 69 is driven by the seventh motor 70 and the eighth motor 72 to be on a glass slide 3 above the conveying groove 54, then the air pump starts to blow in reverse to drop the cell sample liquid in the sampling tube 69 on the glass slide 3, and the whole sampling operation is completed.

[0107] In the embodiment, the heating assembly comprises a heating support and a heating fan, the heating support is arranged on the base 1 and located on the left side of the sampling support 67, and the heating fan is arranged on the heating support and located above the conveying groove 54.

[0108] After the cell sample liquid is dropped on the slide 3 on the conveying groove 54, the slide 3 is driven by the sixth motor to be below the heating fan, and the heating fan starts to work to dry the cell sample liquid on the slide 3.

[0109] In the embodiment, the staining assembly comprises a staining support 75, a staining arm 76, three reagent tubes 77, three reagent bottles 78, a reagent tube cleaning system and a staining suction power system,

[0110] The staining support 75 is arranged on the base 1 and located at the left side of the sampling support 67. The staining arm 76 is arranged on the staining support 75 and can move along the Y-axis and Z-axis directions. The three reagent tubes 77 are arranged on the staining arm 76 in the longitudinal direction. The upper ends of the three reagent tubes 77 are respectively communicated with the reagent tube cleaning system and the staining suction power system through the hoses and the reversing valves. The reagent tube cleaning system provides cleaning water to clean the inside of the reagent tubes 77. The staining suction power system provides suction and suction power for the reagent tubes 77 to realize the suction or discharge of reagents.

[0111] The reagent bottle support is arranged on the base 1. The three reagent bottles 78 are arranged on the reagent bottle support in the left-right direction and side by side. The three reagent bottles 78 are located above the conveying groove 54 and at the left side of the heating fan. The center lines of the three reagent bottles 78 and the three reagent tubes 77 are respectively correspondingly located on three parallel straight lines in the Y-axis direction.

[0112] Specifically, the staining support 75 is provided with a sliding rail along the Y-axis direction. The sliding rail is provided with a sliding block. The sliding block is provided with a tooth block. The tooth block is provided with a pressing block. The pressing block and the tooth block are provided with a toothed belt. The tooth block and the toothed belt are mutually engaged. The staining support 75 located at the front end of the sliding rail is rotatably provided with a toothed belt pulley through a support. The right side of the staining support 75 at the rear end is provided with a ninth motor 79. The main shaft of the ninth motor 79 penetrates the staining support 75 to the left and is provided with a toothed belt pulley. The toothed belt is sleeved on the toothed belt pulleys located at the two ends of the sliding rail. The staining arm mounting plate 80 is arranged on the sliding block.

[0113] The staining arm mounting plate 80 is provided with a sliding rail along the Z-axis direction. The sliding rail is provided with a sliding block. The sliding block is provided with a tooth block. The tooth block is provided with a pressing block. The staining arm 76 is arranged on the sliding block. The pressing block and the tooth block are provided with a toothed belt. The tooth block and the toothed belt are mutually engaged. The staining arm mounting plate 80 located at the lower end of the sliding rail is rotatably provided with a toothed belt pulley through a support. The right side of the staining arm mounting plate 80 at the upper end is provided with a tenth motor. The main shaft of the tenth motor penetrates the staining arm mounting plate 80 to the left and is provided with a toothed belt pulley. The toothed belt is sleeved on the toothed belt pulleys located at the two ends of the sliding rail.

[0114] Through the above design structure can be known: the ninth motor 79 main shaft rotation through the toothed belt, block and gear block to achieve driving dyeing arm mounting plate 80 forward and backward movement, the tenth motor main shaft rotation through the toothed belt, block and gear block to achieve driving dyeing arm 76 up and down movement, and then realize reagent tube 77 on the dyeing support 75 can be along the Y axis and Z axis direction movement;

[0115] Further, the dyeing tube cleaning system includes a water pump, a clean water tank and a water pipe; the dyeing suction power system includes a gas pump and a gas pipe, the water inlet end of the water pump is communicated with the clean water tank through the water pipe, the other end is communicated with one end of a three-way electromagnetic reversing valve through the water pipe, the gas pump is communicated with the other end of the three-way electromagnetic reversing valve through the gas pipe, and finally the other end of the three-way electromagnetic reversing valve is communicated with the upper ends of the three reagent tubes 77 through pipelines respectively. The rear side of the conveying groove 54 and the left side of the dyeing support 75 are also provided with a sewage recovery tank. In this way, when it is necessary to dye the cell sample liquid on the slide 3, the reagent tube 77 is first moved to the upper side of the sewage recovery tank, and then the water pump draws clean water from the clean water tank to flush the inner wall of the reagent tube 77. Then, under the driving of the ninth motor 79 and the tenth motor, the reagent bottle support is moved to the upper side of the reagent bottle support. Three reagent bottles 78 are arranged side by side along the X axis direction on the reagent bottle support. Three second through holes are arranged side by side along the X axis direction on the reagent bottle support, and the three second through holes are located above the conveying groove 54. The three second through holes, the three reagent bottles 78 and the three reagent tubes 77 are respectively located on three parallel straight lines along the Y axis direction. Under the driving of the ninth motor 79 and the tenth motor, the three reagent tubes 77 are first inserted into the three reagent bottles 78 to suck reagent, and then are inserted into the three second through holes on the reagent tube support. At this time, there is a slide 3 dried by heating on the conveying groove 54 below the three second through holes. Then the gas pump starts to blow in the reverse direction to drop the reagent in the reagent tube 77 onto the slide 3, and the whole dyeing operation is completed.

[0116] In the embodiment, the cover slide assembly includes a cover slide box 82, a cover slide box support 83, a cover slide adhering body 84, a suction arm support 85, a suction nozzle 86 and a suction nozzle power system. The cover slide box 82 is internally provided with a cover slide 87,

[0117] The cover slide support 83 is arranged on the rear side of the conveying groove 54 and located on the left side of the dyeing support 75. The cover slide box 82 is movably arranged on the cover slide support 83 along the Y axis direction,

[0118] The suction arm support 85 is arranged on the base 1. The suction arm 84 is movably arranged on the suction arm support 85 along the Z axis direction and located above the conveying groove 54. Two suction nozzles 86 are arranged side by side on the lower end surface of the suction arm 84. The upper end of the suction nozzle 86 is communicated with the suction nozzle power system through a hose. The suction nozzle power system provides suction and suction force for the suction nozzle 86 to realize suction or release of the cover slide 87.

[0119] Two suction nozzles 86 are located on the same line with the center line of the cover glass box 82 along the Y-axis direction;

[0120] Preferably, the cover glass support 83 is further provided with an abnormal cover glass recycling box 103, which is arranged side by side with the cover glass box 82 in front and back and located at the rear side of the cover glass box 82. When the suction nozzle 86 sucks the cover glass 87 with abnormality, the suction nozzle 86 can recycle the abnormal cover glass into the abnormal cover glass recycling box 103.

[0121] Specifically, the cover glass support 83 is provided with a sliding rail along the Y-axis direction, the sliding rail is provided with a sliding block, the cover glass support 83 located at the rear end of the sliding rail is provided with an eleventh motor 88, the main shaft of the eleventh motor 88 penetrates the sliding block forward and is screwed with the sliding block, and the sliding block is provided with the cover glass box 82,

[0122] The suction arm support 85 is provided with a sliding rail along the Z-axis direction, the sliding rail is provided with a sliding block, the suction arm support 85 located at the upper end of the sliding rail is provided with a twelfth motor 89, the main shaft of the twelfth motor 89 penetrates the sliding block downward and is screwed with the sliding block, and the sliding block is provided with the suction arm support 85;

[0123] Through the above design structure, it can be known that the rotation of the main shaft of the eleventh motor 88 drives the cover glass box 82 to move forward and backward through the sliding rail and the sliding block, the rotation of the main shaft of the twelfth motor 89 drives the suction arm support 85 to move up and down through the sliding rail and the sliding block, and then the suction nozzle 86 moves up and down;

[0124] Further, the suction nozzle power system includes a gas pump and a gas pipe, the gas pump is communicated with the upper end of the suction nozzle 86 through the gas pipe. First, the glass slide 3 to be processed is driven by the sixth motor to be below the suction nozzle 86. At this time, the eleventh motor 88 drives the cover glass box 82 to be above the glass slide 3 and below the suction nozzle 86. Then, the twelfth motor 89 drives the suction nozzle 86 to descend and be attached with the cover glass 87 in the cover glass box 82. At the same time, the suction nozzle power system starts to work to achieve the purpose of sucking the cover glass 87 by the suction nozzle 86. Then, the suction nozzle 86 goes up, the cover glass box 82 moves backward to leave the upper side of the conveying groove 54, and then the suction nozzle 86 goes down and cooperates with the reversed gas pump to cover the cover glass on the suction nozzle 86 on the glass slide 3 after dyeing treatment, and then the suction nozzle 86 goes up to complete the whole sealing process.

[0125] In the embodiment, the analysis assembly includes a camera support 90, a camera 91, a slide position adjustment platform 92, a fluorescence module 93 and a lens 94,

[0126] The camera support 90 is arranged on the base 1 and located at the left side of the cover glass box support 83, the camera 91 is movably arranged on the camera support 90 along the Z-axis direction, the fluorescence module 93 is movably arranged on the camera support 90 along the X-axis direction and located below the camera 91, the lens 94 is arranged on the camera support 90 and located below the fluorescence module 93,

[0127] The slide position adjusting platform 92 is movably arranged on the camera support 90 along the X-axis and Y-axis directions, the slide position adjusting platform 92 is located below the lens 94, at the left end of the conveying groove 54 and above the conveying bottom plate 52, the upper surface of the slide position adjusting platform 92 is provided with a slide groove 95, the right end of the slide groove 95 abuts against the left end of the conveying groove 54, the bottom wall of the right end of the slide groove 95 is provided with a second notch 96, the slide groove 95, the second notch 96 and the center line of the first through hole are located on the same straight line along the left-right direction, the camera 91, the fluorescence module 93 and the lens 94 are located on the same plane in the longitudinal direction;

[0128] Specifically, the camera support 90 is provided with a sliding rail along the Z-axis direction, the sliding rail is provided with a sliding block, the camera support 90 above the sliding rail is provided with a thirteenth motor 97, the main shaft of the thirteenth motor 97 penetrates downward through the sliding block and is screwed with the sliding block, and the sliding block is provided with the camera 91,

[0129] The camera support 90 is provided with a sliding rail along the X-axis direction, the sliding rail is provided with a sliding block, the camera support 90 at the right side of the sliding rail is provided with a fourteenth motor 98, the main shaft of the fourteenth motor 98 penetrates leftward through the sliding block and is screwed with the sliding block, and the sliding block is provided with the fluorescence module 93,

[0130] The camera support 90 is provided with another sliding rail along the X-axis direction, the sliding rail is provided with a sliding block, the camera support 90 at the right side of the sliding rail is provided with a fifteenth motor 99, the main shaft of the fifteenth motor 99 penetrates leftward through the sliding block and is screwed with the sliding block, and the sliding block is provided with a slide position adjusting platform connecting plate 100,

[0131] The slide position adjusting platform connecting plate 100 is provided with a sliding rail along the Y-axis direction, the sliding rail is provided with a sliding block, the slide position adjusting platform connecting plate 100 at the rear side of the sliding rail is provided with a sixteenth motor 101, the main shaft of the sixteenth motor 101 penetrates forward through the sliding block and is screwed with the sliding block, and the sliding block is provided with the slide position adjusting platform 92,

[0132] Through the above design structure, it is known that the thirteenth motor 97 rotates the main shaft to drive the camera 91 to move up and down through the slide rail and the sliding block, the fourteenth motor 98 rotates the main shaft to drive the fluorescence module 93 to move left and right through the slide rail and the sliding block, and the fifteenth motor 99 and the sixteenth motor 101 are used to drive the slide position adjustment platform 92 to move along the X-axis and the Y-axis directions.

[0133] On the other hand, after the sealing operation of the slide 3, the sixth motor 66 is driven, and because the second notch 96 is arranged on the bottom wall of the right end of the slide groove 95, and the slide groove 95, the second notch 96 and the center line of the first through hole are located on the same straight line in the left-right direction, so that the slide claw 53 can enter the slide groove 95, and the slide 3 is pushed into the slide groove 95 on the slide position adjustment platform 92 from the left end of the conveying groove 54, and then the sealed slide 3 is driven by the thirteenth motor 97, the fourteenth motor 98, the fifteenth motor 99 and the sixteenth motor 101, so that the center lines of the camera 91, the fluorescence module 93, the lens 94 and the sealed slide 3 are collinear in the Z-axis direction, and finally clear focusing and photographing are achieved. After taking a good image, it is uploaded to the background of the analyzer for corresponding image processing, analysis and diagnosis, and then the final detection and analysis report is issued.

[0134] In the embodiment, the slide recycling box 102 is also included, which is arranged on the base 1 and located below the left end of the slide position adjustment platform 92. After photographing and analyzing, the slide sample falls from the left end of the slide groove 95 on the slide position adjustment platform 92 into the slide recycling box 102, realizing waste recycling and avoiding environmental pollution.

[0135] The biological secretion analyzer provided by the application can compactly, efficiently and stably sample sample cells, realize intelligent pathological detection such as code reading, staining, sealing, scanning, AI analysis and diagnosis, has a pipeline structure layout and compact structure, and is convenient for an operator to take products from the front of the device. The biological secretion analyzer has multi-point online feedback and high intelligence.

[0136] The technical features of the above-described embodiments can be combined in any manner. To make the description concise, all possible combinations of the technical features in the above-described embodiments are not described, but as long as the combinations of the technical features do not exist, they should be considered as the scope of the description.

[0137] The above embodiments only express several implementation manners of the present application, and the description is more specific and detailed, but it should not be understood as a limitation on the patent scope of the present application. It should be noted that for ordinary skilled persons in the art, without departing from the concept of the present application, several modifications and improvements can be made, which are all within the protection scope of the present application. Therefore, the protection scope of the patent of the present application should be subject to the appended claims.

Claims

1. A biological secretion analyzer, characterized in that, The system includes a base on which a test tube rack assembly, a slide box assembly, a slide transport assembly, a barcode scanning assembly, a sampling assembly, a heating assembly, a staining assembly, a sealing assembly, and an analysis assembly are mounted. The test tube rack assembly includes test tubes containing cell sample solution. The slide box assembly includes glass slides; The slide delivery assembly is used to move the slides from the slide box assembly one by one from one side of the base to the other. The barcode scanning component is used to identify the barcode on the test tube; The sampling component is used to extract cell sample solution from the inside of the test tube and drop it onto the surface of a glass slide located on the glass slide delivery component; The heating component is used to heat the cell sample solution on the surface of the glass slide located on the glass slide delivery component; The staining assembly is used to stain cell sample solution on the surface of a heated glass slide. The sealing assembly is used to seal the stained glass slides. The analytical component is used to analyze and process the cell sample solution after it has been sealed. The test tube rack assembly includes a test tube rack, a material rack, and a test tube rack driving mechanism. The test tubes are placed on the test tube rack, the material rack is placed on the base, the material rack is provided with a material tray, the test tube rack is placed on the material tray, and the test tube rack driving mechanism is placed on the material rack. The test tube rack driving mechanism is used to drive the test tube rack placed on the right end of the material tray to the left end of the material tray. The slide cassette assembly includes a slide cassette support, a slide cassette, and slides located inside the slide cassette. The slide cassette support is mounted on the base, and the slide cassette is mounted on the slide cassette support. The slide conveying assembly includes a conveying support, which is mounted on the base. A conveying base plate is mounted on the conveying support, and slide pawls are movably mounted on the conveying base plate. Two conveying slots are arranged side-by-side on the upper part of the conveying base plate, with a gap between the two conveying slots. A first through hole is provided on the base plate of the slide cassette, dividing it into two parts. The slide box has a first notch on the lower edge of each of the two opposite side walls, and the first notch and the first through hole are arranged vertically opposite each other. The width of the first notch on the right side wall of the slide box is smaller than the width of the slide, and the width of the first notch on the left side wall of the slide box is larger than the width of the slide. The height of the first notch is greater than the thickness of the slide. The slide box is located at the right end of the conveying groove, and the center line of the gap between the first through hole and the two conveying grooves is on the same straight line. The upper end of the slide claw is inserted into the channel formed by the gap between the first through hole and the two conveying grooves.

2. The biological secretion analyzer according to claim 1, characterized in that, The barcode scanning assembly includes a scanner bracket mounted on the base, a scanner for scanning barcodes on the surface of test tubes mounted on the scanner bracket, the scanner bracket being located on one side of the middle position of the material tray, and a test tube rotation drive wheel and a test tube rotation auxiliary wheel mounted on the scanner bracket. The test tube rotation drive wheel is positioned above the scanner, and the two test tube rotation auxiliary wheels can be inserted into the gap between test tubes from the rear side of the test tubes and clamp the test tubes. The test tube rotation drive wheel is located on the front side of the test tubes and is used to drive the test tubes to rotate.

3. The biological secretion analyzer according to claim 2, characterized in that, The sampling assembly includes a sampling bracket, a sampling arm, a sampling tube, a sampling tube cleaning system, and a sampling aspiration power system. The sampling bracket is located on the rear side of the delivery tank. The sampling arm is movable along the Y-axis and Z-axis on the sampling bracket. The sampling tube is longitudinally arranged on the sampling arm. The upper end of the sampling tube is connected to the sampling tube cleaning system and the sampling aspiration power system via a flexible tube and a reversing valve, respectively. The sampling tube cleaning system provides cleaning water to clean the inside of the sampling tube. The sampling aspiration power system provides inhalation and suction to the sampling tube to aspirate or expel cell sample fluid.

4. The biological secretion analyzer according to claim 3, characterized in that, The heating assembly includes a heating bracket and a heating fan. The heating bracket is mounted on the base and located to the left of the sampling bracket. The heating fan is mounted on the heating bracket and located above the conveying trough.

5. The biological secretion analyzer according to claim 4, characterized in that, The staining assembly includes a staining support, a staining arm, reagent tubes, a reagent bottle, a reagent tube cleaning system, and a staining aspiration power system. The staining support is mounted on the base and located to the left of the sampling support. The staining arm is movable along the Y-axis and Z-axis on the staining support. Several reagent tubes are longitudinally mounted on the staining arm. The upper ends of the reagent tubes are connected to the reagent tube cleaning system and the staining aspiration power system respectively via flexible tubes and reversing valves. The reagent tube cleaning system provides cleaning water to clean the inside of the reagent tubes. The staining aspiration power system provides inhalation and exhalation force to the reagent tubes to aspirate or expel reagents. The reagent bottle is located above the delivery tank and to the left of the heating fan. The center lines of the reagent bottle and the reagent tubes are aligned along the Y-axis.

6. The biological secretion analyzer according to claim 5, characterized in that, The sealing assembly includes a coverslip box, a coverslip box support, a coverslip mounting body, a suction arm bracket, a suction nozzle, and a suction nozzle power system. The coverslip box contains coverslips. The coverslip support is located behind the delivery channel and to the left of the staining support. The coverslip box is movably mounted on the coverslip support along the Y-axis. The suction arm bracket is mounted on the base. The suction arm is movably mounted on the suction arm bracket along the Z-axis and is located above the delivery channel. The suction nozzle is located on the lower end face of the suction arm. The upper end of the suction nozzle is connected to the suction nozzle power system via a flexible tube. The suction nozzle power system provides suction and exhalation forces to the suction nozzle to aspirate or release the coverslips. The center lines of the suction nozzle and the coverslip box are aligned along the Y-axis.

7. The biological secretion analyzer according to claim 6, characterized in that, The analysis components include a camera bracket, a camera, a slide positioning platform, a fluorescence module, and a lens. The camera bracket is mounted on the base and located to the left of the coverslip holder. The camera is movable along the Z-axis on the camera bracket. The fluorescence module is movable along the X-axis on the camera bracket and located below the camera. The lens is mounted on the camera bracket and located below the fluorescence module. The slide positioning platform is movable along the X and Y axes on the camera bracket. The slide positioning platform is located below the lens, at the left end of the transport channel, and above the transport base plate. A slide groove is provided on the upper surface of the slide positioning platform. The right end of the slide groove abuts against the left end of the transport channel. A second notch is provided on the bottom wall of the right end of the slide groove. The centerline of the slide groove, the second notch, and the first through hole are located on the same straight line in the left-right direction. The camera, fluorescence module, and lens are located on the same plane in the longitudinal direction.

8. The biological secretion analyzer according to claim 7, characterized in that, It also includes a slide recycling box, which is mounted on the base and located below the left end of the slide position adjustment platform.

Citation Information

Patent Citations

  • Full-automatic push piece dyeing machine

    CN115615788A