A perfusion device for use in liver transplantation

Abstract

The application discloses a perfusion device in liver transplantation, which comprises a supporting mechanism, a mounting mechanism, a perfusion box, a pressure balance mechanism and a triggering mechanism, the supporting mechanism comprises a moving base and a supporting column on the top of the moving base, the mounting mechanism is movably connected with the supporting column and used for fixing the perfusion bottle, the perfusion box comprises a transfusion box on the top of which the perfusion bottle is communicated and a transfer box on the bottom of the transfusion box and fixed on the supporting column through a connecting frame, the pressure balance mechanism is installed on the side wall of the transfer box and used for keeping the pressure in the transfer box in a stable state when working, and the triggering mechanism is installed in the perfusion box, the triggering mechanism drives the mounting mechanism to move up and down and drives the pressure balance mechanism to work when the liquid flow in the transfusion box changes, so that the problem that the medical staff needs to manually adjust the pressure of the perfusion liquid in the process of perfusing the liver and it is easy to cause reflux due to insufficient pressure or damage to the liver due to excessive pressure is solved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical device, in particular to a perfusion device in liver transplantation. BACKGROUND

[0002] At present, liver transplantation has become a routine treatment for end-stage liver disease. In recent years, with the continuous promotion and improvement of liver transplantation technology in China, the survival rate after liver transplantation has been continuously improved, and the incidence of postoperative complications has been declining year by year. In liver transplantation, one of the key technologies in obtaining the donor liver is liver perfusion in situ, and a perfusion device needs to be used in this process.

[0003] During the perfusion of the liver, the pressure of the perfusion liquid during the perfusion of the liver and the problem of backflow during the perfusion process need to be paid attention to. Referring to the patents with application numbers CN201510107314.6, CN202111157511.0 and CN202211139336.7, the perfusion device used in the above patents needs medical personnel to observe and judge the flow rate of the perfusion liquid and manually adjust the height of the perfusion bottle to adjust the perfusion speed. It also needs to pay attention to the backflow of the perfusion liquid at all times. In the whole process, medical personnel need to operate manually, and the human operation is subject to many uncontrollable factors. If medical personnel do not observe and handle in time, it is more likely to cause the problem of insufficient perfusion liquid pressure and backflow after the perfusion liquid flow is interrupted, or the problem of excessive perfusion liquid pressure and damage to the liver caused by the excessive flow rate of the perfusion liquid. SUMMARY

[0004] This section aims to summarize some aspects of the embodiments of the present application and briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this section and the abstract and title of the specification to avoid obscuring the purpose of this section, the abstract and the title. Such simplifications or omissions cannot be used to limit the scope of the present application.

[0005] Therefore, the purpose of the present application is to provide a perfusion device in liver transplantation, which replaces the traditional perfusion device in liver transplantation and avoids the need for medical personnel to manually adjust the pressure of the perfusion liquid during the perfusion of the liver, which is more likely to cause the problem of backflow after insufficient pressure or damage to the liver caused by excessive pressure.

[0006] To solve the above technical problems, according to one aspect of the present application, the present application provides the following technical scheme:

[0007] A perfusion device in liver transplantation, comprising:

[0008] a support mechanism comprising a moving base and a support column located at the top of the moving base;

[0009] a mounting mechanism movably connected with the support column, the mounting mechanism being used for fixing the perfusion bottle;

[0010] a perfusion box including a transfusion box with the top communicating with the perfusion bottle and a transfer box fixed on the support column through the connecting frame at the bottom of the transfusion box, the bottom of the transfer box being provided with a transfusion tube with a needle at the end;

[0011] a pressure balance mechanism installed on the side wall of the transfer box, the pressure balance mechanism being used for keeping the pressure in the transfer box stable when working;

[0012] a triggering mechanism installed in the perfusion box, the triggering mechanism driving the mounting mechanism to move up and down relative to the support column and driving the pressure balance mechanism to work when the liquid flow in the transfusion box changes.

[0013] As a preferred scheme of the perfusion device in the liver transplantation, the top of the support column is provided with a lifting groove.

[0014] The mounting mechanism includes a lifting column in the lifting groove and a fixing frame clamped on one side of the lifting column and used for fixing the perfusion bottle.

[0015] As a preferred scheme of the perfusion device in the liver transplantation, the end of the fixing frame away from the lifting column is provided with a fixing groove.

[0016] As a preferred scheme of the perfusion device in the liver transplantation, the fixing frame is provided with a clamping assembly, the clamping assembly including a plurality of springs on the inner wall of the fixing groove and an arc-shaped plate at the end of the plurality of springs away from the inner wall of the fixing groove.

[0017] The clamping assembly is symmetrically provided with two groups in the fixing groove.

[0018] As a preferred scheme of the perfusion device in the liver transplantation, the pressure balance mechanism includes a cylinder on the side wall of the transfer box and communicating with the inside of the transfer box, a piston plate in the cylinder and a first hinged rod hinged at one end of the piston plate.

[0019] As a preferred scheme of the perfusion device in the liver transplantation, the triggering mechanism includes a triggering assembly installed in the transfusion box and used for instant sensing of the flow of the perfusion liquid on the inner wall of the transfusion box and a driving assembly in transmission connection with the triggering assembly and driving the mounting mechanism to move up and down and driving the piston plate to stretch and contract along the inner wall of the cylinder when the triggering assembly works.

[0020] As a preferred scheme of the liver transplantation perfusion device, one side of the inner wall of the infusion tank is provided with a connecting block with a connecting hole in the side wall, and the other side of the inner wall of the infusion tank is provided with a first hinged groove.

[0021] The trigger assembly comprises a trigger plate having a connecting slot at one end and a connecting shaft in the inner wall of the connecting slot, a first rotating plate having a connecting plate hinged at one end of the bottom portion and extending outside the infusion tank, and a second hinged rod hinged at one end of the first rotating plate away from the connecting plate and at the other end to the side wall of the trigger plate, and a torsional spring sleeved on the connecting shaft and connected at one end to the side wall of the connecting shaft and at the other end to the inner wall of the connecting hole.

[0022] As a preferred scheme of the liver transplantation perfusion device, the side wall of the lifting column is uniformly provided with a plurality of sawtooth grooves, and the side of the supporting column close to the perfusion tank is provided with a driving groove extending into the lifting groove.

[0023] The driving assembly comprises a mounting bracket mounted on the side wall of the infusion tank and provided with a second hinged groove and a limiting sliding groove in the side wall, a second rotating plate hinged at one end to the bottom portion of the connecting rod and at the other end to the second hinged groove, a sawtooth plate having a third hinged rod hinged at one end to the second rotating plate and extending into the limiting sliding groove, a first gear fixed to the side wall of the supporting column by a connecting bracket and engaged with the sawtooth plate, a second gear fixed to the side wall of the supporting column by a connecting bracket and engaged with the first gear, and a rotating disc fixed to the side wall of the supporting column by a connecting bracket and provided with a sleeving rod in the side wall, the side wall of the first gear is provided with a first pulley, and the side wall of the rotating disc is provided with a second pulley connected to the first pulley by a belt.

[0024] The second gear is installed in the driving groove and engaged with the plurality of sawtooth grooves in the side wall of the lifting column, and the first hinged rod is sleeved on the sleeving rod away from the piston plate.

[0025] As a preferred scheme of the liver transplantation perfusion device, the distance between the hinged point of the second rotating plate and the second hinged groove and the third hinged rod is much smaller than the distance between the hinged point of the second rotating plate and the second hinged groove and the connecting plate.

[0026] As a preferred scheme of the liver transplantation perfusion device, the side wall of the supporting column is provided with a protective cover covering the driving assembly.

[0027] Compared with the prior art, the liver transplantation perfusion device has the beneficial effects that when the flow of the perfusion liquid in the infusion tank changes, the trigger mechanism works to drive the mounting mechanism to move up and down relative to the support column, thereby adjusting the height of the perfusion bottle, and then adjusting the flow of the perfusion liquid input into the infusion tank from the perfusion bottle, and at the same time, when the flow in the infusion tank changes, the liquid volume in the transfer tank changes, and then the pressure in the transfer tank changes, in order to avoid backflow of the infusion tube, the trigger mechanism simultaneously drives the pressure balance mechanism to work to keep the transfer tank in a pressure balance stable state, replacing the traditional liver transplantation perfusion device, avoiding the problem that the medical staff needs to manually adjust the pressure of the perfusion liquid during the process of perfusing the liver, and it is relatively easy to cause backflow due to insufficient pressure or damage to the liver due to excessive pressure. BRIEF DESCRIPTION OF DRAWINGS

[0028] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the present application will be described in detail below in combination with the drawings and detailed embodiments. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can also be obtained by those skilled in the art without creative labor. Among them:

[0029] Figure 1 It is a structural schematic diagram of the liver transplantation perfusion device of the present application;

[0030] Figure 2 It is a structural exploded view of the liver transplantation perfusion device of the present application;

[0031] Figure 3 It is a sectional view of one state of the liver transplantation perfusion device of the present application;

[0032] Figure 4 It is a sectional view of another state of the liver transplantation perfusion device of the present application;

[0033] Figure 5 It is a structural sectional view of the support structure and the perfusion tank of the liver transplantation perfusion device of the present application;

[0034] Figure 6 It is a structural exploded view of the mounting mechanism of the liver transplantation perfusion device of the present application;

[0035] Figure 7 It is a structural schematic diagram of the pressure balance structure of the liver transplantation perfusion device of the present application;

[0036] Figure 8 It is a structural schematic diagram of the trigger plate of the liver transplantation perfusion device of the present application.

[0037] In the figure: 100, support mechanism; 110, moving base; 120, support column; 120a, lifting groove; 120b, protective cover; 200, mounting mechanism, 210, lifting column; 210a, sawtooth groove; 220, fixing frame; 220a, fixing groove; 220b, clamping assembly; 220b-1, spring; 220b-2, arc plate; 300, perfusion box; 310, infusion box; 310a, connecting block; 310b, first hinged groove; 320, transfer box; 320a, infusion pipe; 400, pressure balance mechanism; 410, cylinder; 420, piston plate; 430, first hinged rod; 500, trigger mechanism; 510, trigger assembly; 510a, trigger plate; 510a-1, connecting groove; 510a-11, connecting shaft; 510a-111, torsional spring; 510b, first rotating plate; 510b-1, connecting plate; 510c, second hinged rod; 520, driving assembly; 520a, mounting frame; 520a-1, second hinged groove; 520a-2, limiting sliding groove; 520b, second rotating plate; 520c, sawtooth plate; 520d, first gear; 520d-1, first belt pulley; 520e, second gear; 520f, rotating disc; 520f-1, second belt pulley; 520f-2, sleeving rod; 600, perfusion bottle. DETAILED DESCRIPTION

[0038] In order to make the above objectives, features and advantages of the present application more obvious and easy to understand, the specific embodiments of the present application will be described in detail below with reference to the drawings.

[0039] Secondly, the present application is described in detail in combination with the schematic diagram. In the detailed description of the embodiments of the present application, the sectional view of the device structure will be partially enlarged without the general proportion for the convenience of description, and the schematic diagram is only an example which should not limit the scope of protection of the present application herein. In addition, the three-dimensional spatial dimensions of length, width and depth should be included in the actual manufacture.

[0040] In order to make the objectives, technical solutions and advantages of the present application more clear, the embodiments of the present application will be further described in detail below with reference to the drawings.

[0041] The present application provides a perfusion device in liver transplantation, which replaces the traditional perfusion device in liver transplantation, avoids the need for medical personnel to manually adjust the pressure of the perfusion liquid during the process of perfusing the liver, and is more likely to cause reflux due to insufficient pressure or damage to the liver due to excessive pressure.

[0042] Figures 1-8 The structure of the perfusion device in liver transplantation is shown. Please refer to Figures 1-8 The perfusion device in liver transplantation is described in detail.

[0043] In some embodiments

[0044] refer to Figures 1-8 The present invention discloses a perfusion device for liver transplantation, the main body of which includes a support mechanism 100, an installation mechanism 200, a perfusion box 300, a pressure balancing mechanism 400, and a triggering mechanism 500.

[0045] refer to Figures 1-5 The support mechanism 100 is used to support the entire device. The support mechanism 100 includes a movable base 110 and a support column 120 located on top of the movable base 110. The movable base 110 is used to facilitate the movement of the entire device, and the support column 120 is used to facilitate the installation of the installation mechanism 200, the filling box 300 and the triggering mechanism 500.

[0046] In this embodiment, reference Figure 2 The top of the support column 120 is provided with a lifting groove 120a for storing the lifting column 210, thereby facilitating the lifting column 210 to move up and down within the lifting groove 120a.

[0047] In this embodiment, a drive groove (not shown in the figure) extending into the lifting groove 120a is provided on the side of the support column 120 near the injection box 300, which facilitates the second gear 520e to pass through the drive groove and mesh with the lifting column 210 inside the lifting groove 120a.

[0048] In this embodiment, reference Figure 1 The side wall of the support column 120 is provided with a protective cover 120b to cover the drive assembly 520, so as to prevent the first gear 520d, the second gear 520e, the first pulley 520d-1 and the second pulley 520f-1 from causing accidental injury to the surrounding medical staff when they rotate.

[0049] refer to Figures 1-6 The mounting mechanism 200 is movably connected to the support column 120, and the mounting mechanism 200 is used to fix the filling bottle 600.

[0050] In this embodiment, reference Figure 6 The installation mechanism 200 includes a lifting column 210 located in the lifting groove 120a and a fixing frame 220 that is clipped to one side of the lifting column 210 and used to fix the filling bottle 600. The lifting column 210 moves up and down in the lifting groove 120a, which drives the filling bottle 600 fixed on the mounting frame 520a to move up and down.

[0051] In this embodiment, reference Figure 6 The side wall of the lifting column 210 is evenly provided with multiple sawtooth grooves 210a for meshing with the second gear 520e, thereby driving the lifting column 210 to move up and down when the second gear 520e rotates.

[0052] In the embodiment, referring to Figure 6 , the fixing frame 220 is provided with a fixing groove 220a at one end away from the lifting column 210, for facilitating fixing of the perfusion bottle 600.

[0053] In the embodiment, referring to Figures 1-5 , the perfusion box 300 is used for perfusing the perfusion liquid in the perfusion bottle 600 into the liver, and the perfusion box 300 comprises a transfusion box 310 at the top of the perfusion bottle 600 and a transfer box 320 at the bottom of the transfusion box 310 and fixed on the support column 120 through a connecting frame, the perfusion liquid flows into the transfusion box 310 through a catheter and then enters the transfer box 320, the perfusion liquid stays in the transfer box 320 for a short time, thereby avoiding the liver from stopping perfusion during replacement when the perfusion liquid in the perfusion bottle 600 is used up, and the bottom of the transfer box 320 is provided with a transfusion tube 320a with a needle at the end, for inputting the perfusion liquid in the transfer box 320 into the liver;

[0054] In the embodiment, referring to Figure 5 , the inner wall of the transfusion box 310 is provided with a connecting block 310a with a connecting hole in the side wall, for facilitating cooperation with the connecting shaft 510a-11, realizing hinging between the trigger plate 510a and the inner wall of the transfusion box 310, and the inner wall of the transfusion box 310 is provided with a first hinging groove 310b at the other side, for hinging with the first stirring rod 410c.

[0055] In the embodiment, referring to Figure 7 , the pressure balance mechanism 400 is installed on the side wall of the transfer box 320, and the pressure balance mechanism 400 is used for keeping the pressure in the transfer box 320 stable during work, thereby avoiding backflow of the perfusion liquid in the transfusion tube 320a when the perfusion liquid in the transfer box 320 is less to form negative pressure, or causing damage to the liver due to excessive flow in the transfusion tube 320a when the perfusion liquid in the transfer box 320 is too much to cause excessive pressure.

[0056] In the embodiment, referring to Figure 7 , the pressure balance mechanism 400 comprises a cylinder 410 located on the side wall of the transfer box 320 and communicating with the inside of the transfer box 320, a piston plate 420 located in the cylinder 410, and a first hinging rod 430 hinged at one end to the piston plate 420, the piston plate 420 is driven to move in the cylinder 410 through the first hinging rod 430, thereby adjusting the air pressure in the transfer box 320.

[0057] In the embodiment, referring to Figures 3-5The triggering mechanism 500 is installed in the perfusion box 300, and when the flow of the liquid in the infusion box 310 changes, the triggering mechanism 500 drives the mounting mechanism 200 to move up and down relative to the support column 120 and drives the pressure balancing mechanism 400 to work, so that when the flow of the perfusion liquid in the infusion box 310 is too large or too small, the mounting mechanism 200 is driven to move up and down, and then the perfusion bottle 600 is driven to move up and down, so that the height of the perfusion bottle 600 is adjusted to adjust the speed of the liquid outflow, and the pressure change in the transfer box 320 is adjusted by the pressure balancing mechanism 400, so as to avoid backflow caused by the decrease of the internal pressure or damage to the liver caused by the increase of the internal pressure;

[0058] In the embodiment, the triggering mechanism 500 includes a triggering assembly 510 installed in the infusion box 310 for instant sensing of the flow of the perfusion liquid on the inner wall of the infusion box 310, and a driving assembly 520 in transmission connection with the triggering assembly 510 and driving the mounting mechanism 200 to move up and down and driving the piston plate 420 to extend and retract along the inner wall of the cylinder 410 when the triggering assembly 510 works. Figure 3 The triggering assembly 510 instantaneously senses the flow of the perfusion liquid on the inner wall of the infusion box 310, and when the triggering assembly 510 senses that the flow of the perfusion liquid in the infusion box 310 changes, the driving assembly 520 is driven to work to adjust the height of the perfusion bottle 600 and the pressure balancing mechanism 400 balances and adjusts the pressure in the transfer box 320.

[0059] In the embodiment, the triggering mechanism 500 includes a triggering assembly 510 installed in the infusion box 310 for instant sensing of the flow of the perfusion liquid on the inner wall of the infusion box 310, and a driving assembly 520 in transmission connection with the triggering assembly 510 and driving the mounting mechanism 200 to move up and down and driving the piston plate 420 to extend and retract along the inner wall of the cylinder 410 when the triggering assembly 510 works. Figures 2-3 The triggering assembly 510 includes a triggering plate 510a having a connecting slot 510a-1 at one end and the inner wall of the connecting slot 510a-1 having a connecting shaft 510a-11, a first rotating plate 510b having a connecting plate 510b-1 hinged at the bottom of one end and extending out of the infusion box 310, and a second hinged rod 510c hinged to the side wall of the triggering plate 510a at one end and hinged to the ground at the other end. Figure 2 When the flow in the infusion box 310 decreases, the triggering plate 510a rotates relative to the inner wall of the infusion box 310 under the torsion of the torsional spring 510a-111, at this time the first rotating plate 510b rotates under the connecting action of the first connecting plate, and then drives the connecting plate 510b-1 to descend. Figure 3 When the flow in the infusion box 310 increases, the connecting plate 510b-1 rises.

[0060] In the embodiment, the triggering mechanism 500 includes a triggering assembly 510 installed in the infusion box 310 for instant sensing of the flow of the perfusion liquid on the inner wall of the infusion box 310, and a driving assembly 520 in transmission connection with the triggering assembly 510 and driving the mounting mechanism 200 to move up and down and driving the piston plate 420 to extend and retract along the inner wall of the cylinder 410 when the triggering assembly 510 works. Figures 2-3 Figure 7 ​, the driving assembly 520 comprises a mounting frame 520a mounted on the side wall of the infusion tank 310 and provided with a second hinge groove 520a-1 and a limiting sliding groove 520a-2, a second rotating plate 520b hingedly connected at one end to the bottom of the connecting rod and at the other end to the second hinge groove 520a-1, a zigzag plate 520c extending to the bottom into the limiting sliding groove 520a-2 and hingedly connected at the bottom to a third hinge rod at the other end of the second rotating plate 520b, a first gear 520d fixed on the side wall of the supporting column 120 by a connecting frame and engaged with the zigzag plate 520c, a second gear 520e fixed on the side wall of the supporting column 120 by a connecting frame and engaged with the first gear 520d, and a rotating disc 520f fixed on the side wall of the supporting column 120 by a connecting frame and provided with a sleeve rod 520f-2 on the side wall, with reference to Figure 3 , when the connecting plate 510b-1 descends, the second rotating plate 520b is driven to rotate, and the zigzag plate 520c is driven to move upward in the limiting sliding groove 520a-2 under the connection of the third hinge rod, when the zigzag plate 520c moves upward in the limiting sliding groove 520a-2, the first gear 520d is driven to rotate, when the first gear 520d rotates, the second gear 520e is driven to rotate, when the second gear 520e rotates, the lifting column 210 is driven to move upward, thereby adjusting the height of the infusion bottle 600 and increasing the speed of liquid outflow, the side wall of the first gear 520d is provided with a first belt pulley 520d-1, the side wall of the rotating disc 520f is provided with a second belt pulley 520f-1 connected with the first belt pulley 520d-1 by a belt, when the first gear 520d rotates to drive the first belt pulley 520d-1 to rotate, the first belt pulley 520d-1 is driven to rotate, thereby driving the rotating disc 520f to rotate, when the rotating disc 520f rotates, the piston plate 420 is driven to move into the cylinder 410 under the connection of the first hinge rod 430, thereby increasing the air pressure in the intermediate tank 320, avoiding the negative pressure formed after the liquid in the intermediate tank 320 is reduced, causing the infusion pipe 320a to flow back, and by analogy, when the connecting plate 510b-1 moves upward due to the increase in the flow rate of the infusion liquid in the infusion tank 310, with reference to Figure 3 , the infusion bottle 600 descends, thereby slowing down the speed of liquid outflow, the piston column moves to the side away from the intermediate tank 320 to suck air, thereby reducing the air pressure in the intermediate tank 320, achieving the effect of automatically adjusting the height of the infusion bottle 600 and balancing the air pressure in the intermediate tank 320;

[0061] , the second gear 520e is installed in the driving groove and engaged with a plurality of zigzag grooves 210a on the side wall of the lifting column 210, for driving the lifting column 210 to move up and down when the first gear 520d rotates, the first hinge rod 430 is sleeved on the sleeve rod 520f-2 at the end away from the piston plate 420, for realizing the cam connection between the first hinge rod 430 and the rotating disc 520f.

[0062] In the present embodiment, the specific use process is as follows: during perfusion of the liver, when the flow rate in the infusion tank 310 changes, the reference Figures 2-3 , the trigger mechanism 500 drives the perfusion bottle 600 on the mounting mechanism 200 to perform lifting movement, thereby adjusting the speed of the liquid outlet of the perfusion bottle 600, and at the same time, the mounting mechanism 200 performs lifting movement, and the pressure balancing mechanism 400 works to keep the pressure in the transfer tank 320 stable, avoiding excessive pressure and too fast flow rate in the infusion pipe 320a causing damage to the liver, or too small pressure, negative pressure in the transfer tank 320, and backflow in the infusion pipe 320a, thereby achieving the effect of automatically adjusting the pressure in the perfusion bottle 600 and the transfer tank 320 without manual adjustment by medical staff.

[0063] In other embodiments

[0064] Referring to Figure 6 , the fixed frame 220 is provided with a clamping assembly 220b for clamping and fixing perfusion bottles 600 of different sizes. The clamping assembly 220b includes a plurality of springs 220b-1 located on the inner wall of the fixed groove 220a and an arc-shaped plate 220b-2 located at one end of the plurality of springs 220b-1 away from the inner wall of the fixed groove 220a, which wraps the outer sidewall of the perfusion bottle 600 through the arc-shaped plate 220b-2.

[0065] The clamping assembly 220b is symmetrically provided with two groups in the fixed groove 220a, and the outer sidewall of the perfusion bottle 600 is wrapped by the arc-shaped plates 220b-2 of the two groups of clamping assemblies 220b, and the perfusion bottle 600 is clamped by the rebound force generated by the springs 220b-1 of the two groups of clamping assemblies 220b.

[0066] In other embodiments

[0067] Referring to Figure 3 , the distance between the second rotating plate 520b and the second hinge slot 520a-1 and the third hinge rod is much smaller than the distance between the second rotating plate 520b and the connecting plate 510b-1, so that the force arm for driving the sawtooth plate 520c to lift is smaller than the force arm for driving the second rotating plate 520b to rotate by the connecting rod lifting, and then the force for driving the sawtooth plate 520c to lift is greater than the force for driving the second rotating plate 520b to rotate by the connecting rod lifting, which plays a certain force increasing role through the lever principle, and then better adjusts the height of the perfusion bottle 600, avoiding that the trigger mechanism 500 cannot operate due to excessive gravity.

[0068] Although the present application has been described with reference to the embodiments above, various changes and modifications can be suggested to one skilled in the art, and it is intended that the present application encompass such changes and modifications as fall within the scope of the appended claims. Particularly, each feature disclosed in the description and / or the claims can be used in the combination with each of the features disclosed in the description and / or the claims, unless specifically stated otherwise. Therefore, the present application is not intended to be limited to the particular embodiments disclosed in the description and / or the claims.

Claims

1. A perfusion device for use in liver transplantation, characterized in that The application relates to a perfusion device, which comprises a supporting mechanism (100), a mounting mechanism (200), a perfusion box (300) and a pressure balance mechanism (400). The supporting mechanism (100) comprises a moving base (110) and a supporting column (120) arranged on the top of the moving base (110). The mounting mechanism (200) is movably connected with the supporting column (120) and is used for fixing a perfusion bottle (600). The perfusion box (300) comprises a transfusion box (310) and a transfer box (320) arranged on the bottom of the transfusion box (310) and fixed on the supporting column (120) through a connecting frame, and the bottom of the transfer box (320) is provided with a transfusion pipe (320a) with a needle head at the end. The pressure balance mechanism (400) is arranged on the side wall of the transfer box (320) and is used for keeping the pressure in the transfer box (320) stable during work. The trigger mechanism (500) is arranged in the perfusion box (300) and drives the mounting mechanism (200) to move up and down relative to the supporting column (120) and drives the pressure balance mechanism (400) to work when the liquid flow in the transfusion box (310) changes. The top of the supporting column (120) is provided with a lifting groove (120a). The mounting mechanism (200) comprises a lifting column (210) arranged in the lifting groove (120a) and a fixing frame (220) clamped on one side of the lifting column (210) and used for fixing the perfusion bottle (600). The pressure balance mechanism (400) comprises a cylinder (410) arranged on the side wall of the transfer box (320) and communicated with the inside of the transfer box (320), a piston plate (420) arranged in the cylinder (410) and a first hinged rod (430) hinged at one end with the piston plate (420). The trigger mechanism (500) comprises a trigger assembly (510) arranged in the transfusion box (310) and used for instant sensing the flow of perfusion liquid on the inner wall of the transfusion box (310) and a driving assembly (520) drivingly connected with the trigger assembly (510) and driving the mounting mechanism (200) to move up and down and driving the piston plate (420) to stretch and contract along the inner wall of the cylinder (410) when the trigger assembly (510) works. One side of the inner wall of the transfusion box (310) is provided with a connecting block (310a) with a connecting hole in the side wall, and the other side of the inner wall of the transfusion box (310) is provided with a first hinged groove (310b). The trigger assembly (510) comprises a trigger plate (510a) having a connecting slot (510a-1) at one end and the inner wall of the connecting slot (510a-1) having a connecting shaft (510a-11), a first rotating plate (510b) having a connecting plate (510b-1) hinged at one end of the bottom and extending outside the infusion tank (310) in the first hinged slot (310b), and a second hinged rod (510c) hinged at one end of the first rotating plate (510b) away from the connecting plate (510b-1) and hinged at the other end of the side wall of the trigger plate (510a), the connecting shaft (510a-11) is sleeved with a torsional spring (510a-111) having one end connected with the side wall of the connecting shaft (510a-11) and the other end connected with the inner wall of the connecting hole; The side wall of the lifting column (210) is uniformly provided with a plurality of sawtooth grooves (210a), and the side of the supporting column (120) close to the infusion tank (300) is provided with a driving groove extending into the lifting groove (120a); The driving assembly (520) comprises a mounting bracket (520a) mounted on the side wall of the infusion tank (310) and provided with a second hinged slot (520a-1) and a limiting sliding groove (520a-2) on the side wall, a second rotating plate (520b) hinged at one end of the connecting rod and at the other end of the second hinged slot (520a-1), a sawtooth plate (520c) having a third hinged rod hinged at the other end of the second rotating plate (520b) and extending into the limiting sliding groove (520a-2), a first gear (520d) fixed on the side wall of the supporting column (120) through a connecting bracket and engaged with the sawtooth plate (520c), a second gear (520e) fixed on the side wall of the supporting column (120) through a connecting bracket and engaged with the first gear (520d), and a rotating disc (520f) fixed on the side wall of the supporting column (120) through a connecting bracket and having a sleeving rod (520f-2) on the side wall, the side wall of the first gear (520d) is provided with a first pulley (520d-1), and the side wall of the rotating disc (520f) is provided with a second pulley (520f-1) connected with the first pulley (520d-1) through a belt. The second gear (520e) is installed in the driving groove and engaged with the plurality of sawtooth grooves (210a) on the side wall of the lifting column (210), and the first hinged rod (430) is sleeved on the sleeving rod (520f-2) away from the piston plate (420).

2. The device according to claim 1, wherein The fixed frame (220) is provided with a fixed slot (220a) at one end away from the lifting column (210).

3. A perfusion device for use in liver transplantation as defined in claim 2, wherein The fixing frame (220) is provided with a clamping assembly (220b), which comprises a plurality of springs (220b-1) located on the inner wall of the fixing groove (220a) and an arc-shaped plate (220b-2) located at the end of the plurality of springs (220b-1) away from the inner wall of the fixing groove (220a). The clamping assembly (220b) is symmetrically provided with two groups in the fixing groove (220a).

4. The device according to claim 3, wherein the device is used in a liver transplantation surgery. The distance between the second rotating plate (520b) and the hinging point of the second hinging groove (520a-1) to the third hinging rod is much smaller than the distance to the connecting plate (510b-1).

5. A perfusion device for use in liver transplantation as defined in claim 4, wherein The sidewall of the supporting column (120) is provided with a protective cover (120b) for covering the driving assembly (520).

Images