Tick-repelling mite composition and tick-repelling mite product

Abstract

The present invention provides a repellent composition for mites which is excellent in mite-repelling effect against indoor mites even after a long period of time and is also excellent in safety to humans and animals. The present invention relates to a repellent composition for mites, which contains: (a) 1,8-cineol and / or 1,4-cineol and (b) a perfume ingredient, wherein the perfume ingredient contains one or two or more kinds of perfume compounds having a logP value of 2.0 to 5.5. The mixing ratio (a) / (b) of the (a) ingredient to the perfume compounds contained in the (b) ingredient is set to 5 to 100 on a mass basis. The perfume compounds contained in the (b) ingredient are at least one selected from the group consisting of ethyl cinnamate, allyl caproate, 3-methyl-5-phenyl-1-pentanol, citronellol, δ-dodecalactone, β-ionone, benzyl benzoate, linalyl acetate, geranyl acetate, tricyclo decenyl propionate, benzyl salicylate, limonene, and amyl salicylate.

Description

TECHNICAL FIELD

[0001] The present application relates to a repellent composition and a repellent product for repelling indoor acarid. BACKGROUND

[0002] In recent years, due to changes in living environments, indoor acarid such as Tyroglyphus, Dermatophagoides, Acarus, and Cheyletiella have been proliferating in large numbers. Indoor acarid not only causes discomfort, but also causes problems such as allergic asthma or skin rash. Furthermore, it is known that the corpse of Dermatophagoides, which causes allergic asthma, itself causes allergy. Therefore, although an indoor acaricidal agent for treating bedding such as a pillow, a quilt, or a throw pillow has been developed, there is a demand for an indoor acaricidal agent that is safe even when it comes into direct contact with the skin.

[0003] In view of the above, there have been several proposals for a technique that does not kill indoor acarid, but makes acarid inaccessible to humans or patients. For example, in Patent Literature 1, as an effective ingredient of an indoor acaricidal agent, a plant essential oil such as oil of vetiver, oil of patchouli, and oil of clove is disclosed. In addition, in Patent Literature 2, citronellal, linalool, and citral are disclosed. These prior arts claim natural origin and safety concerns, but the repellent effect on indoor acarid is not necessarily satisfactory.

[0004] In addition, eucalyptol has attracted attention as a repellent ingredient. Patent Literature 3 discloses an indoor acarid repellent containing 1,8-eucalyptol as an effective ingredient. However, 1,8-eucalyptol and 1,4-eucalyptol are not easy to make the acarid repellent effect last for a long time of 2 to 3 months or more because of their high volatility.

[0005] PRIOR ART DOCUMENTS

[0006] PATENT LITERATURE

[0007] Patent Literature 1: Japanese Patent Application Laid-Open No. 6-16515

[0008] Patent Literature 2: Japanese Patent Application Laid-Open No. 2001-294505

[0009] Patent Literature 3: Japanese Patent Application Laid-Open No. 2001-31508 SUMMARY

[0010] PROBLEMS TO BE SOLVED BY THE INVENTION

[0011] The present application has been achieved in view of the above problems, and aims to provide a repellent composition and a repellent product for repelling indoor acarid, which are excellent in acarid repellent effect even after a long time, and are excellent in safety to humans and animals.

[0012] MEANS FOR SOLVING THE PROBLEMS

[0013] The tick-repelling mite composition according to the present application for solving the above problems is characterized in that

[0014] It is a tick-repelling mite composition containing (a) 1,8-cineole and / or 1,4-cineole and (b) a perfume ingredient, wherein

[0015] The above-mentioned perfume ingredient contains one or two or more kinds of perfume compounds having a logP value of 2.0 to 5.5.

[0016] According to the tick-repelling mite composition according to the present constitution, as its formulation, (b) a perfume ingredient is further contained on the basis of (a) 1,8-cineole and / or 1,4-cineole. Here, since the perfume ingredient contains one or two or more kinds of perfume compounds having a logP value of 2.0 to 5.5, the excellent tick-repelling mite effect of (a) 1,8-cineole and / or 1,4-cineole, which is higher in volatility, on indoor dust mites can be continued for a long time by the perfume compounds having a logP value of 2.0 to 5.5 contained in (b). Further, since (a) and (b) are excellent in safety to humans and animals, high safety as a tick-repelling mite composition can be achieved.

[0017] In the tick-repelling mite composition according to the present application, it is preferable that

[0018] The mixing ratio (a) / (b) of the above-mentioned perfume compounds contained in (a) and (b) is set to 5 to 100 on a mass basis.

[0019] According to the tick-repelling mite composition according to the present constitution, since the mixing ratio (a) / (b) of the perfume compounds contained in (a) and (b) is set to an appropriate range, both the excellent tick-repelling mite effect on indoor dust mites and the high safety to humans and animals can be achieved.

[0020] In the tick-repelling mite composition according to the present application, it is preferable that

[0021] The above-mentioned perfume compounds contained in (b) are at least one selected from the group consisting of ethyl cinnamate, allyl caproate, 3-methyl-5-phenyl-1-pentanol, citronellol, δ-dodecalactone, β-ionone, benzyl benzoate, linalyl acetate, geranyl acetate, tricyclo decenyl propionate, benzyl salicylate, limonene, and amyl salicylate.

[0022] According to the tick-repelling mite composition according to the present constitution, since the perfume compounds contained in (b) are selected from appropriate compounds, the excellent tick-repelling mite effect of (a) can be stably continued for a long time.

[0023] The tick-repelling mite product according to the present application for solving the above problem is characterized by comprising:

[0024] a solid carrier containing any of the above-described tick-repelling mite compositions; and

[0025] a gas-permeable packaging material that accommodates or packages the solid carrier.

[0026] The tick-repelling mite product according to the present constitution is in the form of an article in which the solid carrier containing the tick-repelling mite composition according to the present application is accommodated or packaged in the gas-permeable packaging material, and is low in cost and can achieve a tick-repelling mite product that has both an excellent tick-repelling mite effect on indoor dust mites and a high safety to humans and animals.

[0027] In the tick-repelling mite product according to the present application, it is preferable that:

[0028] The solid carrier is a granular material having an average particle diameter of 1 mm to 8 mm.

[0029] The tick-repelling mite product according to the present constitution can stably volatilize the tick-repelling mite composition from the solid carrier for a long time because the average particle diameter of the solid carrier is made to be an appropriate size. Furthermore, it can be made into a tick-repelling mite product that is good in convenience of use and high in practicality.

[0030] In the tick-repelling mite product according to the present application, it is preferable that:

[0031] The above-described (a) component is contained in an amount of 20 mg to 400 mg per 1 g of the above-described solid carrier.

[0032] The tick-repelling mite product according to the present constitution can maintain a high safety while exerting an excellent tick-repelling mite effect on indoor dust mites because the solid carrier contains an appropriate amount of the (a) component. DETAILED DESCRIPTION

[0033] The tick-repelling mite composition and the tick-repelling mite product according to the present application will be described below. However, the present application is not limited to the constitution or the examples described below.

[0034] <tick-repelling mite composition>

[0035] The tick-repelling mite composition according to the present application contains 1,8-cineole and / or 1,4-cineole as a (a) component and a perfume component as a (b) component. Here, the (b) component contains at least one perfume compound having a logP value of 2.0 to 5.5, as described later.

[0036] [(a) component]

[0037] The 1,8-cineol and / or 1,4-cineol used as the (a) component functions as a tick mite repellent component. The 1,8-cineol is a substance rich in eucalyptus oil; the 1,4-cineol is a substance rich in pepper oil, and both have a cooling scent. The 1,8-cineol and 1,4-cineol are generally known as a cough suppressant and an antiviral agent, and are low in toxicity, non-irritating, and non-sensitizing to the human body. Furthermore, as described in the background art, the 1,8-cineol and 1,4-cineol are high in volatility, and when used as a tick mite repellent component, the tick mite repellent effect does not last for a long period of time of 2 to 3 months or more.

[0038] Furthermore, as a result of the present inventors' intensive research on adjustment of the volatility of the tick mite repellent composition containing the 1,8-cineol and / or 1,4-cineol as the (a) component, it was found that by incorporating a perfume compound having a logP value of 2.0 to 5.5, which is included in the (b) component described later, the volatility of the 1,8-cineol and / or 1,4-cineol can be effectively adjusted, and an excellent tick mite repellent effect can be exerted on indoor dust mites even after a long period of time. In addition, the tick mite repellent composition of the present application is highly safe to humans and animals, and is extremely practical and useful.

[0039] The tick mite repellent composition of the present application is prepared by adding various components to the (a) component and the (b) component described later, and can be applied to various forms of tick mite repellent products. The amount of the (a) component to be incorporated with respect to the total amount of the tick mite repellent product varies depending on the form of the tick mite repellent product, and is preferably about 0.02 g to 1.0 g per tick mite repellent product. If it is a pillow or a throw pillow, it is convenient to use one. If it is a large bedding such as a cotton quilt or a mattress, the number of applications can be increased as needed. In the present application, the (a) component can use the 1,8-cineol and 1,4-cineol as a single substance, or can use eucalyptus oil or pepper oil rich in these substances as an active ingredient. For example, eucalyptus oil having a content of 1,8-cineol of 70% by mass or more can be widely obtained as a commercial product. The (a) component can also use a mixture of 1,8-cineol and 1,4-cineol, and from the viewpoint of the tick mite repellent effect, it is preferable to use 1,8-cineol.

[0040] The amount of the (a) component to be incorporated in the tick mite repellent composition is preferably 10% by mass to 90% by mass, and more preferably 20% by mass to 85% by mass.

[0041] [(b) component]

[0042] The perfume ingredient used as the component (b) functions as a volatility adjusting ingredient. Here, the component (b) contains one or two or more kinds of perfume compounds having a logP value of 2.0 to 5.5. That is, the perfume ingredient includes a case where one kind of perfume compound is contained, and a case where two or more kinds of perfume compounds are contained. When the perfume ingredient contains one kind of perfume compound, the logP value of the one kind of perfume compound is 2.0 to 5.5. When the perfume ingredient contains two or more kinds of perfume compounds, the logP value of each of the two or more kinds of perfume compounds is preferably 2.0 to 5.5, but at least one kind of perfume compound having a logP value of 2.0 to 5.5 is sufficient. By incorporating the component (b) containing a perfume compound having a logP value of 2.0 to 5.5 in the acarid-repelling mite composition, the volatility of the component (a) can be effectively adjusted, and an excellent acarid-repelling effect on indoor mites can be exerted even after a long period of time. The preferable range of the logP value of the perfume compound contained in the component (b) is 3.0 to 5.0. Here, the logP value is a coefficient indicating the affinity of an organic compound to 1-octanol and water. The 1-octanol / water partition coefficient P is the ratio of the equilibrium concentration of a compound in each solvent in a partition equilibrium when a trace amount of the compound is dissolved as a solute in two liquid phases of 1-octanol and water, and is generally expressed in the form of a logarithm logP of the ratio to the base number 10. Furthermore, the logP value described in the present specification is not a measured value, but a calculated value calculated by a dedicated application program (Advanced Chemistry Development (ACD / Labs) Software V11.02).

[0043] The perfume compound having a logP value of 2.0 to 5.5 contained in the component (b) is not particularly limited, and a monocyclic or chain perfume compound can be used. The perfume compound having a logP value of 2.0 to 5.5 described above can be exemplified by the following compounds. The numbers in the [] after the perfume compound indicate the logP value.

[0044] alcohols such as eugenol [2.4], α-terpineol [2.7], linalool [2.8], geraniol [2.9], 3-methyl-5-phenyl-l-pentanol [3.2], citronellol [3.2], phenylhexanol [3.4], tetrahydrolinalool [3.5], and the like, methyl cinnamate [2.5], γ-decalactone [2.5], methyl dihydrojasmonate [2.6], ethyl benzoate [2.6], cinnamyl acetate [2.6], hexyl acetate [2.8], ethyl cinnamate [3.0], γ-undecalactone [3.0], δ-undecalactone [3.0], tricyclo decenyl acetate [3.1], allyl hexanoate [3.1], benzyl phenyl acetate [3.5], γ-dodecalactone [3.5], δ-dodecalactone [3.5], benzyl cinnamate [3.8], benzyl benzoate [3.8], linalyl acetate [3.9], geranyl acetate [3.9], 2-phenylethyl phenyl acetate [3.9], tricyclodecenyl propionate [4.0], benzyl salicylate [4.2], cyclohexyl salicylate [4.5], amyl salicylate [4.6], hexyl salicylate [5.1], cyclopentadecanolide (pentalide) [5.2], and the like, ester-based flavor compounds, β-ionone [3.3], α-ionone [3.4], β- ionone [3.6], α-ionone [3.7], and the like, ketone-based flavor compounds, amyl cinnamic aldehyde [4.4], hexyl cinnamic aldehyde [4.9], and the like, aldehyde-based flavor compounds, limonene [4.6], and the like, hydrocarbon-based flavor compounds, and the like.Among them, one or more selected from the group consisting of monocyclic or chain type perfume compounds and having a logP value of 3.0 or more and 5.0 or less: 3-methyl-5-phenyl-l-pentanol [3.2], citronellol [3.2], phenylhexanol [3.4], tetrahydro-ligustral [3.5], ethyl cinnamate [3.0], γ-undecalactone [3.0], δ-undecalactone [3.0], tricyclo decenyl acetate [3.1], allyl hexanoate [3.1], benzyl phenyl acetate [3.5], γ-dodecalactone [3.5], δ-dodecalactone [3.5], benzyl cinnamate [3.8], benzyl benzoate [3.8], linalyl acetate [3.9], geranyl acetate [3.9], 2-phenylethyl phenyl acetate [3.9], tricyclodecenyl propionate [4.0], benzyl salicylate [4.2], cyclohexyl salicylate [4.5], amyl salicylate [4.6], β-damascenone [3.3], α-damascenone [3.4], β-ionone [3.6], α-ionone [3.7], amyl cinnamic aldehyde [4.4], hexyl cinnamic aldehyde [4.9], and limonene [4.6] are preferable. Among them, ethyl cinnamate [3.0], allyl hexanoate [3.1], 3-methyl-5-phenyl-l-pentanol [3.2], citronellol [3.2], δ-dodecalactone [3.5], β-ionone [3.6], benzyl benzoate [3.8], linalyl acetate [3.9], geranyl acetate [3.9], tricyclodecenyl propionate [4.0], benzyl salicylate [4.2], limonene [4.6], and amyl salicylate [4.6] are preferable. These perfume compounds can be used alone or as a mixture of two or more.

[0045] Further, the logP value of 1,8-cineol and / or 1,4-cineol used as the (a) component is: 1,8-cineol [2.8], 1,4-cineol [2.4]. As for the logP value of these (a) components and the logP value of the perfume compounds contained in the above (b) component, since the values show a part of the repetition or proximity, the (a) component and the (b) component are in harmony at the molecular level. Furthermore, it is presumed that thus the following effects of the present application are exerted: the (b) component containing the above perfume compounds effectively adjusts the volatility of the (a) component, and the acaricidal effect against the indoor acarid such as acarus siro, dermatophagoides farinae, glycyphagus domesticus, and predaceous mites is also excellent even after a long period of time.

[0046] The blending amount of the perfume compound contained in the (b) component in the acaricidal composition is preferably 0.01 to 20 mass%, more preferably 0.1 to 10 mass%.

[0047] The mixing ratio (a) / (b) of the component (a) to the perfume compound contained in the component (b) is preferably set to 5 to 100, more preferably 5 to 80 on a mass basis. When the mixing ratio (a) / (b) is within the above range, the volatility of the 1,8-cineole and / or 1,4-cineole in the component (a) can be effectively adjusted, and a high safety can be ensured, and an excellent repellent effect against dust mites can be exerted even after a long period of time. Thus, both the excellent repellent effect against dust mites and the high safety to humans and animals can be achieved.

[0048] [Other components]

[0049] In the repellent composition of the present application, in addition to the components (a) and (b) described above, various solvents such as water, alcohol-based solvents such as ethanol and isopropanol, diol-based solvents such as 1,3-butanediol, propylene glycol and dipropylene glycol, diol ether-based solvents such as diethylene glycol monobutyl ether and propylene glycol monomethyl ether, aliphatic hydrocarbon-based solvents such as n-alkanes and isomeric alkanes, surfactants (solubilizers) and the like can be appropriately mixed. In addition, the repellent composition of the present application can be prepared without adding other components such as solvents in addition to the components (a) and (b) described above.

[0050] The surfactant can be exemplified by nonionic surfactants such as polyoxyethylene hydrogenated castor oil, polyoxyethylene higher alkyl ether (polyoxyethylene lauryl ether, polyoxyethylene oleyl ether), polyoxyethylene higher fatty acid ester, polyoxyethylene polyoxypropylene alkyl ether, higher alkyl amine oxide-based surfactants such as lauryl amine oxide, stearyl amine oxide, lauric acid amide propyl dimethyl amine oxide, and the like. The surfactants described above can be used alone or as a mixture of two or more.

[0051] In addition, in the repellent composition of the present application, an antibacterial component, a mildew-proof component, a deodorant component, an aromatic component, an insecticidal component, an insect repellent component, a stabilizing agent, a pH adjusting agent, a coloring agent, a gelling agent, and the like can be appropriately mixed. Further, for example, leaf alcohol (cis-3-hexen-1-ol) or leaf aldehyde, which is called "green fragrance", and the like can be added. Thus, a relaxing effect can be imparted, and a good sleep can be promoted.

[0052] The antibacterial component can include, for example, isopropylmethylphenol (IPMP), carvacrol, thymol, triclosan, methyl p-hydroxybenzoate, ethyl p-hydroxybenzoate, propyl p-hydroxybenzoate, butyl p-hydroxybenzoate, 4-chloro-3,5-dimethylphenol, o-phenylphenol, o-cresol, m-cresol, and p-cresol, and the like, phenol-based antibacterial components, benzalkonium chloride, benzalkonium methosulfate, benzalkonium organic acid salts, benzethonium chloride, benzethonium methosulfate, benzethonium organic acid salts, benzethonium salts, cetyl pyridinium chloride, cetyl pyridinium methosulfate, cetyl pyridinium organic acid salts, cetyl pyridinium salts, didecyldimethylammonium chloride, didecyldimethylammonium methosulfate, didecyldimethylammonium salts, dilauryldimethylammonium chloride, dilauryldimethylammonium methosulfate, dilauryldimethylammonium salts, distearyldimethylammonium chloride, distearyldimethylammonium methosulfate, distearyldimethylammonium salts, and 1,4-bis[3,3'-(1-decylpyridinium)methoxy]butane dibromide, 1,4-bis[3,3'-(1-decylpyridinium)methoxy]butane dichloride, 1,4-bis[3,3'-(1-decylpyridinium)methoxy]butane dimethyl sulfate, and the like, 1,4-bis[3,3'-(1-decylpyridinium)methoxy]butane salts, and the like.3 '-(1-decylpyridinium) methoxy] butane salt and the like cationic surfactant-based antibacterial ingredients, biguanide-based antibacterial ingredients, azole-based antibacterial ingredients such as uniconazole, enilconazole, fruit seed extract-based antibacterial ingredients such as grapefruit seed extract, persimmon seed extract, grape seed extract, glycerol mono fatty acid ester-based antibacterial ingredients such as glycerol monolaurate, glycerol monocaprate, glycerol monocaprylate, chlorhexidine salts or chlorhexidine-based antibacterial ingredients such as chlorhexidine gluconate, chlorhexidine hydrochloride, and chlorhexidine, silicon-based antibacterial ingredients such as octadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, dodecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, dodecyl diisopropyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, octadecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, octadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, and the like, carboxylic acid-based antibacterial ingredients or their salts such as benzoic acid, salicylic acid, sorbic acid, ethylenediaminetetraacetic acid (EDTA), glycine, alkyl diethylamino glycine, polylysine, dehydroacetic acid, chloramine, 3-iodo-2-propyl-N-butylcarbamic acid ester (IPBC), phenoxyethanol, silver zeolite, silver-based antibacterial ingredients such as silver zeolite, zinc pyrithione, thiamine lauryl sulfate, fish albumin protein, hydroxyalkyl chitosan or its salts, and the like. The above antibacterial ingredients can be used alone or as a mixture of two or more.

[0053] As the antifungal component, there are, for example, isopropylmethylphenol (IPMP), carvacrol, thymol, triclosan, methyl-p-hydroxybenzoate, ethyl-p-hydroxybenzoate, propyl-p-hydroxybenzoate, butyl-p-hydroxybenzoate, 4-chloro-3,5-dimethylphenol, o-phenylphenol, o-cresol, m-cresol, p-cresol, and the like, phenol-based antifungal components, benzalkonium chloride, benzalkonium methosulfate, benzalkonium organic acid salts, benzethonium chloride, benzethonium methosulfate, benzethonium organic acid salts, cetylpyridinium chloride, cetylpyridinium methosulfate, cetylpyridinium organic acid salts, didecyldimethylammonium chloride, didecyldimethylammonium methosulfate, didodecyldimethylammonium chloride, didodecyldimethylammonium methosulfate, dioleoyl dimethylammonium chloride, dioleoyl dimethylammonium methosulfate, distearyldimethylammonium chloride, distearyldimethylammonium methosulfate, and the like, and 1,4-bis[3,3'-(1-decylpyridinium)methoxy]butane dibromide, 1,4-bis[3,3'-(1-decylpyridinium)methoxy]butane dichloride, 1,4-bis[3,3'-(1-decylpyridinium)methoxy]butane dimethylsulfate, and the like, 1,4-bis[3,3'-(1-decylpyridinium)methoxy]butane salts.3 '-(1-decylpyridinium) methoxyl] butane salt and the like cationic surfactant-based antifungal ingredients, biguanide-based antifungal ingredients, azole-based antifungal ingredients such as tebuconazole, enilconazole, fruit seed extract-based antifungal ingredients such as grapefruit seed extract, persimmon seed extract, grape seed extract, glycerol mono fatty acid ester-based antifungal ingredients such as glycerol monolaurate, glycerol monocaprate, glycerol mono- caprylate, chlorhexidine salts or chlorhexidine-based antifungal ingredients such as chlorhexidine gluconate, chlorhexidine hydrochloride, silicone-based antifungal ingredients such as octadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, dodecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, dodecyl diisopropyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, octadecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, octadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, and the like, carboxylic acid-based antifungal ingredients or their salts such as benzoic acid, salicylic acid, sorbic acid, ethylenediaminetetraacetic acid (EDTA), glycine, alkyl diethylamino glycine, polylysine, dehydroacetic acid, chloramine, 3-iodo-2-propyl-N-butylcarbamic acid ester (IPBC), phenoxyethanol, silver zeolite, zinc pyrithione, thiamine lauryl sulfate, fish albumin protein, hydroxyalkyl chitosan or its salt, and antifungal fragrances. The above-mentioned antifungal ingredients can be used alone or as a mixture of two or more.

[0054] Deodorizing ingredients can be exemplified by, for example, plant-derived deodorizing ingredients. Plant-derived deodorizing ingredients can be exemplified by plant extracts extracted from plants of the Gramineae family, Theaceae family, Ginkgoaceae family, Oleaceae family, Moraceae family, Rutaceae family, Euphorbiaceae family, Ebenaceae family, and the like. The above-mentioned plant extracts can be used alone or as a mixture of two or more; representative examples can be exemplified by green tea extract or persimmon extract.

[0055] Gelation agents can be exemplified by, for example, carrageenan, xanthan gum, gellan gum, gelatin, aluminum octanoate, 12-hydroxy stearic acid, and the like. The above-mentioned gelation agents can be used alone or as a mixture of two or more.

[0056] <Tick and mite repellent product>

[0057] The tick-repelling product of the present application contains the above-mentioned tick-repelling composition of the present application, which can be formulated into various forms such as solid, liquid, gel, etc. in accordance with the use situation or the needs of the consumer. Among them, the product form in which the tick-repelling composition is impregnated or held in a solid carrier and then stored or packaged in a gas-permeable material is preferred. The tick-repelling product is only placed under or near a pillow, a throw pillow, or a cotton quilt, a mattress, etc., and the tick-repelling component can be effectively volatilized from the solid carrier, thus being low in cost and achieving a tick-repelling product with excellent tick-repelling effect on indoor dust mites and high safety to humans and animals.

[0058] As the solid carrier, there can be mentioned pulp such as cellulose pulp, fibrous carriers such as cotton flock, rayon, cellulose (regenerated cellulose) beads or foams, inorganic porous carriers such as silicates, silicon dioxide, zeolite, sublimable carriers such as trioxane, adamantane, etc. Among these, pulp such as cellulose pulp, fibrous carriers such as cotton flock, rayon, cellulose (regenerated cellulose) beads are preferred, and cellulose pulp is more preferred.

[0059] When the solid carrier is made into beads (granules), the average particle diameter is usually 1 mm to 8 mm, preferably 3 mm to 8 mm, and more preferably 4 mm to 7 mm. The apparent specific gravity of the solid carrier is usually about 0.10 to 0.35, and preferably 0.15 to 0.30. For example, as long as 20 mg to 400 mg, preferably 30 mg to 300 mg, of the above-mentioned (a) 1,8-cineol and / or 1,4-cineol is contained per 1 g of cellulose pulp, and it is stored in a gas-permeable packaging material, a useful and practical tick-repelling product of the present application can be obtained.

[0060] The gas-permeable packaging material can be mentioned as nonwoven fabric bags, cotton bags, net sleeves, perforated plastic containers, etc. Among these, nonwoven fabric bags are preferred in terms of convenience of use. The material of the nonwoven fabric bag can be mentioned as, for example, polyester (PET), polyethylene (PE), polypropylene (PP), polyamide, polylactic acid, rayon, etc. The nonwoven fabric bag can be composed of a single fiber, or it can be a laminate or a blend of polyester, polypropylene / rayon, etc. in which paper is laminated. Among these, polyester, polyethylene, and polypropylene are preferred in terms of the possibility of secondary adjustment of the amount of volatilization of the above-mentioned (a) 1,8-cineol and / or 1,4-cineol by partial adsorption. The shape and composition of the nonwoven fabric bag can also be appropriately determined, for example, both sides can be composed of nonwoven fabric of the above-mentioned material, or one side can be composed of nonwoven fabric of the above-mentioned material and the other side can be composed of a plastic film having a large number of small holes, and these can be adhered together.

[0061] The application site of the acaricidal product of the present application thus obtained is not particularly limited, and the acaricidal product can be used by being disposed under or near a carpet, a tatami, a pillow, a throw pillow, a comforter, a mattress, or the like; and is preferably used as a bedding material for a pillow, a throw pillow, a comforter, a mattress, or the like. As long as the acaricidal product is disposed under or near a pillow, a throw pillow, a comforter, a mattress, or the like, the acaricidal component is volatilized from the solid carrier through the air-permeable material, and can exert a practical repellent effect on various pests such as house dust mites, dermanyssus sibiricus, acarapis oatae, tyrophagus putrescentiae, carwidae, dermestidae, psocoptera, blattaria, formicidae, culicidae, simuliidae, diptera, and moth flies for a long period of 1 month to 6 months. The acaricidal product of the present application can particularly effectively exert a repellent effect on house dust mites, dermanyssus sibiricus, acarapis oatae, tyrophagus putrescentiae, and carwidae.

[0062] [Examples]

[0063] The present application will be specifically described below based on examples.

[0064] [Example 1]

[0065] An acaricidal composition was prepared by directly mixing 400 mg of 1,8-cineole as the (a) component and 8 mg of 3-methyl-5-phenyl-1-pentanol as the (b) component. About 8 g of cellulose-made paper pulp particles having an average particle diameter of 5.5 mm and an apparent specific gravity of 0.21 were impregnated with the entire amount of the acaricidal composition. Then, the cellulose-made paper pulp particles impregnated with the acaricidal composition were accommodated in a nonwoven fabric bag (9 x 12 cm) composed of a mixed nonwoven fabric of air-permeable polyethylene / polypropylene on both sides, to obtain the acaricidal product of Example 1.

[0066] [Examples 2 to 11, Comparative Examples 1 and 2, Reference Examples 1 to 3]

[0067] An acaricidal composition containing the (a) component and the (b) component was prepared according to the formulation shown in Table 1 and Example 1, and various acaricidal products of Examples 2 to 11, Comparative Examples 1 and 2, and Reference Examples 1 to 3 were obtained in the same order as in Example 1.

[0068] [Table 1]

[0069]

[0070] [Repellent effect test]

[0071] Each of the acaricidal products of Examples 1 to 11, Comparative Examples 1 and 2, and Reference Examples 1 to 3 was wrapped with a woolen blanket, 4 kg of a heavy stone was placed thereon, and the woolen blanket was left to stand at room temperature for 2 months. Thereafter, each of the acaricidal products was recovered.

[0072] Next, a 50 cm square cotton cloth was uniformly spread with a culture medium containing about 100,000 European house dust mites for measurement. Each of the acaricide products after standing for 2 months was placed on a pillow and covered with a pillowcase, and 1 g of an attractant culture medium was spread on the surface of the pillow, and the pillow was left on the center of the cotton cloth, which served as a treated area. In addition, the same operation was performed using a pillow on which no acaricide product was placed, which served as an untreated area. Then, the number of acarid that invaded the pillowcase after 24 hours was counted, and the acarid repellent effect (repellency) was calculated according to the following formula.

[0073] Acarid repellent effect (%) = (N0- N1) / N0 x 100

[0074] N0: Number of invading mites in the untreated area

[0075] N1: Number of invading mites in the treated area

[0076] The results of the acarid repellent effect test are shown in Table 2.

[0077] [Table 2]

[0078]

[0079] It was found that the acarid repellent products of Examples 1 to 11 all exhibited excellent acarid repellent effects of 80% or more after 2 months. It is considered that the inclusion of the (b) component comprising a perfume compound having a logP value of 2.0 to 5.5 effectively adjusts the volatilization of the (a) 1,8-cineole and / or 1,4-cineole, and thus excellent acarid repellent effects can be achieved over a long period of time in the acarid repellent products of Examples 1 to 11. Among these, it was found that the acarid repellent products of Examples 1, 3 to 7, 10, and 11, which contain (a) 1,8-cineole and the (b) component comprising a perfume compound having a logP value of 3.0 to 5.0, all exhibited acarid repellent effects of 85% or more after 2 months, and are more excellent.

[0080] On the other hand, the acarid repellent product of Reference Example 1, which contains cyclonexanone (logP value: 5.7) having a logP value higher than 5.5 as the (b) component, or the acarid repellent product of Reference Example 2, which contains butyl acetate (logP value: 1.8) having a logP value lower than 2.0 as the (b) component, exhibited poor acarid repellent effects over a long period of time compared with the acarid repellent products of Examples 1 to 11. With respect to the perfume compounds having logP values deviating from 2.0 to 5.5, it was analyzed that the adjustment of the volatilization of 1,8-cineole was slightly poor. From the comparison of Examples 1 to 11 with Reference Examples 1 to 3, it was found that the inclusion of the (b) component comprising a perfume compound having a logP value of 2.0 to 5.5 in (a) 1,8-cineole and / or 1,4-cineole can further improve the acarid repellent effects over a long period of time.

[0081] Further, the tick-repelling agent of Comparative Example 1 and Comparative Example 2, in which the component (a) is compounded with other citronellal or vetiver oil, even if the component (b) containing a perfume compound having a logP value of 2.0 to 5.5 is compounded, the effect of repelling ticks and mites is still insufficient after a long period of time. From this analysis, the phenomenon that the perfume compound having a logP value of 2.0 to 5.5 contained in the component (b) can effectively adjust the volatilization of the tick-repelling component is unique to the component (a) 1,8-cineole and / or 1,4-cineole.

[0082] Industrial applicability

[0083] The tick-repelling composition and tick-repelling agent of the present application can be suitably used for the purpose of repelling indoor dust mites hidden in bedding (tick-repelling composition and tick-repelling agent for bedding); not only for repelling indoor dust mites, but of course for a wide range of uses for repelling insects.

Claims

1. A tick and mite repellent composition comprising: (a) 1,8-cineole and / or 1,4-cineole and (b) a perfume ingredient, the (b) ingredient contains one or two or more ester-based perfume compounds having a logP value of 3.0 to 5.0, a blending ratio (a) / (b) of the (a) ingredient to the ester-based perfume compound contained in the (b) ingredient is set to 5 to 100 on a mass basis.

2. The tick and mite repellent composition according to claim 1, wherein the ester-based perfume compound contained in the (b) ingredient is at least one selected from the group consisting of allyl hexanoate, benzyl benzoate, linalyl acetate, tricyclo decenyl propionate, benzyl salicylate, and amyl salicylate.

3. A tick and mite repellent article comprising: a solid carrier containing the tick and mite repellent composition according to claim 1 or 2; and a gas-permeable packaging material that houses or packages the solid carrier.

4. The tick and mite repellent article according to claim 3, wherein the solid carrier is a granular material having an average particle diameter of 1 mm to 8 mm.

5. The tick and mite repellent article according to claim 3 or 4, wherein 20 mg to 400 mg of the (a) ingredient is contained per 1 g of the solid carrier.

6. The tick and mite repellent article according to claim 3 or 4, wherein a blending amount of the (a) ingredient relative to the total amount of the tick and mite repellent article is 0.02 g to 1.0 g per tick and mite repellent article.

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