A reusable dehydrating agent drying device for drug preparation

Abstract

The present application relates to a dehydrating agent drying device for drug preparation that can be reused, and relates to the technical field of drying devices. It includes a reaction tank, a discharge port is provided on the side wall of the reaction tank, a discharge assembly is provided on the reaction tank for sending anhydrous sulfuric acid in the reaction tank out from the discharge port, a drying assembly is provided above the discharge port, the drying assembly is arranged on the outer wall of the reaction tank, a horizontally arranged conveyor belt is provided below the drying assembly, the conveyor belt is located below the discharge port, the conveyor belt includes a driving wheel, a driven wheel and a belt, the driving wheel and the driving wheel are both vertically arranged on the outer wall of the reaction tank, the belt is sleeved on the driving wheel and the driving wheel, a support plate is inserted in the belt, the support plate is horizontally arranged on the outer wall of the reaction tank, a top push rod is slidably connected to the support plate, and when the top push rod moves vertically on the support plate, it drives the belt between the driving wheel and the driven wheel to fluctuate up and down. The present application has the effect of relatively uniform drying of anhydrous magnesium sulfate.

Description

Technical Field

[0001] The present application relates to the field of drying equipment, and in particular to a reusable dehydrating agent drying equipment for drug preparation. Background Art

[0002] In the process of drug preparation, some dehydrating agents are often used for dehydration operation. For example, in the preparation of avibactam, L-pyroglutamic acid is used as the starting reaction substrate, and its carboxylic acid site and amide nitrogen site are protected by benzyl and Boc groups respectively, followed by nucleophilic ring opening using trimethylsulfonyl ylide to obtain sulfur ylide inner salt, which is then subjected to chlorination condensation with benzyloxyamine hydrochloride, followed by removal of Boc protection by methanesulfonic acid, and ring closure by replacing chlorine atom with amino group catalyzed by base, followed by reduction of ketoxime with sodium triacetylborohydride to obtain (2S, 5R)-5-[(benzyloxy)amino]-piperidine-2-carboxylic acid benzyl ester intermediate; the intermediate ester is aminolyzed by methanol solution of ammonia and reacted with N, N-carboxydiimidazole to synthesize urea ring, which is then debenzylated, sulfonated and acidified to finally obtain the target molecule avibactam.

[0003] In the above preparation process, dehydrating agents such as anhydrous magnesium sulfate or anhydrous sodium sulfate need to be used multiple times to dry the solution, and the effective solution is filtered out to achieve the purification effect. Anhydrous magnesium sulfate can be reused as a commonly used dehydrating agent. In order to achieve energy saving, an independent drying device is generally provided in the process of preparing avibactam to dry the anhydrous magnesium sulfate after water absorption, so that the anhydrous magnesium sulfate is fully dehydrated to ensure its water absorption capacity for next use.

[0004] In the related technology, a Chinese patent with authorization announcement number CN214892249U and publication date of November 26, 2021, discloses an anhydrous magnesium sulfate production and drying device, including a drying device body, anhydrous magnesium sulfate is accumulated in a drying and disinfection box, and a drying heat bar is fixed on the inner wall of the drying and disinfection box. During drying, the drying heat bar generates heat, so that the drying and disinfection box is in a high temperature state, thereby achieving drying of the anhydrous magnesium sulfate in the drying and disinfection box.

[0005] During the drying process, the drying heat strip only dries the surface portion of the accumulated anhydrous magnesium sulfate, while the middle portion of the accumulated anhydrous magnesium sulfate can only be dried by heat transfer from the surface portion of the accumulated anhydrous magnesium sulfate, resulting in uneven drying of the accumulated anhydrous magnesium sulfate, which needs to be improved. Summary of the invention

[0006] In order to improve the problem of uneven drying of anhydrous magnesium sulfate, the present application provides a reusable dehydrating agent drying device for drug preparation.

[0007] A dehydrating agent drying device for drug preparation that can be reused adopts the following technical solution:

[0008] A dehydrating agent drying device for drug preparation that can be reused, comprising:

[0009] A reaction tank, wherein a discharge port is formed through the side wall of the reaction tank;

[0010] A discharge assembly, arranged on the reaction tank, for sending the dehydrating agent after absorbing water in the reaction tank out of the discharge port;

[0011] A conveying conveyor belt, arranged on the outer side wall of the reaction tank and located below the discharge port. The conveying conveyor belt includes a driving wheel, a driven wheel and a belt. The driving wheel and the driven wheel are arranged on the reaction tank, the belt is sleeved on the driving wheel and the driven wheel, and the belt is used for receiving the dehydrating agent moved out of the discharge port;

[0012] A drying assembly, arranged on the outer side wall of the reaction tank, for drying the dehydrating agent on the belt;

[0013] A support plate, horizontally arranged on the outer side wall of the reaction tank. The support plate (50) is inserted into the belt (43) and located between the driving wheel and the driven wheel;

[0014] A top push rod, slidably connected to the support plate, and the top push rod abuts against the belt;

[0015] A driving assembly, arranged on the support plate, and the driving assembly is used for driving the top push rod to lift the belt.

[0016] By adopting the above technical solution, when the dehydrating agent that has absorbed more moisture needs to be used for drying the next solution in the reaction tank, the dehydrating agent in the reaction tank is pushed out of the reaction tank from the discharge port by using the discharge assembly. The dehydrating agent falls onto the belt, and the gravity of the dehydrating agent exerts a downward pressure on the belt, causing the belt between the driving wheel and the driven wheel to sag until the inner wall of the belt abuts against the top wall of the support plate. The support plate plays a supporting role, so that the belt will not continue to move down and break. In the initial state, the top end of the top push rod is flush with the top wall of the support plate.

[0017] When drying the dehydrating agent, first start the drying assembly to emit heat to the belt, manually pull the belt to move, so that the position of the dehydrating agent on the belt relative to the top push rod changes, that is, the dehydrating agent moves to the position of the top push rod. Then move the top push rod upward, so that the top end of the top push rod pushes the part of the belt between the driving wheel and the driven wheel to deform and arch upward. Then move the top push rod downward, and the belt restores its deformation and moves downward closely against the top end of the top push rod until the belt returns to its original state, so that the belt continuously undulates up and down.

[0018] During this process, the dehydrating agent located on the belt is continuously broken up and will not accumulate together, increasing the contact area between the dehydrating agent and heat, enabling the dehydrating agent to be evenly dried. At the same time, the dehydrating agents will also collide and roll over each other, so that the dehydrating agents on the belt can be fully dried, and thus there will be no phenomenon of only drying a dehydrating agent at a fixed position. The drying is relatively uniform and the efficiency is relatively high.

[0019] Optionally, the driving assembly includes:

[0020] A driving conveyor belt, which is horizontally arranged below the top push rod and is rotatably connected to the support plate;

[0021] A number of driving rods, which are arranged on the outer side wall of the driving conveyor belt. A guiding surface for abutting against the driving rods is arranged at the bottom of the top push rod, and the end of the guiding surface close to the driving conveyor belt is inclined in the moving direction of the driving conveyor belt.

[0022] By adopting the above technical solution, when the water-absorbed dehydrating agent is placed on the belt, the belt abuts against the top end of the top push rod under the pressure of the dehydrating agent. Then, the driving conveyor belt is rotated so that the top end of the driving rod moves to abut against the guiding surface and slides along the guiding surface. The guiding surface plays a guiding role, enabling the top push rod to move upward, realizing pushing the top push rod upward. When the driving rod moves to separate from the top push rod, the top push rod loses the upward moving force, the belt restores its deformation, presses down the top push rod, and makes the top push rod reset. Then, the next driving rod moves to abut against the guiding surface and pushes the top push rod upward again. Repeating the above steps makes the top push rod move up and down continuously, thereby driving the belt to undulate up and down continuously.

[0023] Optionally, a number of mounting blocks are fixed on the outer wall of the driving conveyor belt. The number of mounting blocks is arranged along the length direction of the driving conveyor belt. An installation hole is opened on the side of the mounting block away from the driving conveyor belt, and one end of the driving rod is threadedly connected to the inner wall of the installation hole.

[0024] By adopting the above technical solution, after one end of the driving rod is screwed tightly into the installation hole, the installation of the driving rod on the driving conveyor belt can be realized. Similarly, when the driving rod is moved away from the mounting block until the driving rod is pulled out of the installation hole, the disassembly of the driving rod on the driving conveyor belt can be realized, so that the distance between adjacent driving rods can be adjusted, that is, the time interval for pushing the top push rod upward can be adjusted, and further the undulating frequency of the belt can be adjusted. Thus, the undulating frequency of the belt can be adjusted according to the amount of the dehydrating agent on the belt, and the applicability is good.

[0025] Optionally, a roller is rotatably connected to the top end of the top push rod, and the roller abuts against the side of the belt that contacts the driving wheel and the driven wheel.

[0026] By adopting the above technical solution, when the driving driving wheel rotates to drive the belt to move, the inner wall of the belt abuts and slides on the roller, thereby driving the roller to rotate. That is, the original sliding friction between the belt and the top of the push rod becomes rolling friction, reducing the frictional force suffered by the belt during movement. Therefore, compared with the belt sliding on the push rod, the belt is not easily damaged by friction, the service life of the belt is prolonged, and the movement of the belt is smoother.

[0027] Optionally, a limiting plate is provided above the belt. The limiting plate is used to prevent the dehydrating agent from slipping out of the belt from the end in the length direction of the belt. The limiting plate is arranged on the outer wall of the reaction tank. A baffle is fixed on the outer side wall of the reaction tank. The baffle is arranged vertically. The side of the belt away from the reaction tank abuts against the baffle, and the baffle extends upward to the discharge port.

[0028] By adopting the above technical solution, when the driving wheel drives the belt to move, the limiting plate and the baffle play a limiting role, so that the dehydrating agent on the belt will not fall out of the edge of the belt, increasing the stability of the dehydrating agent on the belt. When the dehydrating agent is pushed out by the discharging assembly from the discharge port, it is easy to move in a parabolic trajectory, and the baffle extends to the discharge port, restricting the dehydrating agent from crossing the belt, increasing the stability of the dehydrating agent falling onto the belt.

[0029] Optionally, the discharging assembly includes:

[0030] A receiving plate, the receiving plate is horizontally installed in the reaction tank, the circumferential side wall of the receiving plate abuts and is fixed to the inner wall of the reaction tank, the top wall of the receiving plate is flush with the bottom wall of the discharge port, and a filtering hole is penetrated through the receiving plate;

[0031] A sealing plate, which is arranged in the filtering hole to block the filtering hole;

[0032] A rotating rod, the rotating rod is horizontally arranged and rotatably connected to the receiving plate, one end of the rotating rod extends out of the reaction tank, and the rotating rod is fixedly connected to the sealing plate for driving the sealing plate to rotate;

[0033] A push plate, the bottom wall of the push plate abuts against the top wall of the receiving plate, a discharging driving part is arranged on the side wall of the reaction tank, the output end of the discharging driving part is fixed with the push plate, and the discharging driving part can drive the push plate to move on the receiving plate in a direction close to or away from the discharge port.

[0034] By adopting the above technical solution, when in use, pour the solution into the reaction tank. In the initial state, the circumferential side walls of the sealing plate are all in contact with the inner walls of the filtering holes, blocking the filtering holes, that is, the filtering holes are in a closed state. Thus, the solution is blocked above the receiving plate by the receiving plate and contacts the dehydrating agent on the receiving plate. The dehydrating agent absorbs the moisture in the solution and dries the solution. Then drive the rotating rod to rotate, driving the sealing plate to rotate, so that the side wall of the sealing plate is separated from the inner wall of the filtering hole, thereby creating a gap between the sealing plate and the inner wall of the filtering hole, that is, the filtering holes are in an open state. The dried solution leaks out of the receiving plate through the filtering holes and deposits at the bottom of the reaction tank for storage.

[0035] When the dehydrating agent needs to perform the next drying operation, start the discharging driving member to drive the pushing plate to move on the receiving plate in the direction close to the discharging port, thereby pushing the dehydrating agent that has absorbed water on the receiving plate out of the reaction tank from the discharging port. The dehydrating agent falls onto the belt for drying and is ready for the next use.

[0036] Optionally, a feeding mechanism is provided on the reaction tank. The feeding mechanism is used to send the dried dehydrating agent back into the reaction tank. The feeding mechanism includes:

[0037] A lifting assembly, which is arranged on the reaction tank and is used to drive the conveying belt to move up and down;

[0038] A feeding driving member, which is arranged on the baffle. The output end of the feeding driving member is fixed with a feeding plate. The feeding driving member drives the feeding plate to move horizontally and can pass through the discharging port.

[0039] By adopting the above technical solution, when the dehydrating agent on the belt is dried, use the lifting assembly to drive the conveying belt to align with the discharging port. At this time, the top wall of the belt is higher than the bottom wall of the discharging port. Then start the feeding driving member to drive the feeding plate to move in the direction close to the reaction tank, so that the feeding plate pushes the dried dehydrating agent on the belt into the reaction tank through the discharging port. The dehydrating agent falls onto the receiving plate and accumulates. The feeding plate continues to move, thereby pushing the part of the accumulated dehydrating agent higher than the belt in the direction away from the belt, playing a leveling role, so that the dried dehydrating agent is evenly laid on the receiving plate, facilitating the next drying.

[0040] Optionally, the lifting assembly includes:

[0041] A mounting plate, which is slidably connected to the outer side wall of the reaction tank. The driving wheel and the driven wheel are rotatably connected to the side of the mounting plate away from the reaction tank. The limiting plate and the supporting plate are both fixed on the mounting plate;

[0042] A lifting driving member, which is fixedly arranged on the outer side wall of the reaction tank. The output end of the lifting driving member is vertically upward and is fixed to the mounting plate. The lifting driving member drives the mounting plate to move up and down.

[0043] By adopting the above technical solution, when the dehydrating agent after absorbing water is dried on the belt, the lifting driving member is started to push the mounting plate upward until the belt moves to align with the discharge port. During this process, since the limiting plate is fixed on the mounting plate, the limiting plate always blocks both sides in the length direction of the belt. At the same time, the baffle also always blocks the side of the belt away from the reaction tank, so that during the movement of the belt, the dehydrating agent on the belt is not easily slipped off the belt.

[0044] Optionally, a guiding block is fixed on the side wall of the mounting plate, and a guiding groove is vertically formed on the outer side wall of the reaction tank. The guiding block is inserted into the guiding groove and can move in the guiding groove.

[0045] By adopting the above technical solution, when the lifting driving member pushes the mounting plate to move, the guiding block moves in the guiding groove, and the inner wall of the guiding groove abuts against the side wall of the guiding block, which plays a role in restricting and guiding the guiding block, so that the mounting plate can only move along the vertical direction and is not easily offset, increasing the stability of the movement of the mounting plate. It also makes the belt not tilt, that is, the dehydrating agent on the belt does not slip off the belt, increasing the stability of the dehydrating agent placed on the belt.

[0046] Optionally, a moving groove is formed on the side wall of the reaction tank. The central axis of the moving groove is perpendicular to the central axis of the discharge port. The moving groove is communicated with the discharge port, and a sealing plate for blocking the discharge port is inserted into the moving groove. The sealing plate can move in the moving groove.

[0047] By adopting the above technical solution, after the dehydrating agent is laid on the receiving plate, the sealing plate is inserted into the moving groove and moves in the moving groove until one side of the sealing plate perpendicular to the moving direction of the sealing plate abuts against the inner wall of the discharge port, so that the sealing plate blocks the discharge port and restricts the dehydrating agent from moving out of the reaction tank. When the dehydrating agent needs to be moved out of or fed into the reaction tank, the sealing plate is moved in the direction away from the reaction tank until the sealing plate is completely received in the moving groove, that is, the discharge port is in an open state, facilitating the passage of the dehydrating agent.

[0048] In summary, the present application includes at least one of the following beneficial effects:

[0049] 1. Move the top push rod upward so that the top end of the top push rod pushes the part of the belt between the driving wheel and the driven wheel to deform and arch upward. Then move the top push rod downward, and the belt restores its deformation, closely adhering to the top end of the top push rod and moving downward until the belt is restored to its original state, thus making the belt continuously undulate up and down. During this process, the dehydrating agent on the belt is continuously dispersed and will not accumulate together, increasing the contact area between the dehydrating agent and heat, enabling the dehydrating agent to be evenly dried, and preventing the phenomenon of only drying the dehydrating agent at one place. The drying is relatively uniform and efficient.

[0050] 2. Drive the conveyor belt to rotate so that the top end of the driving rod moves to abut against the guiding surface and slides along the guiding surface. The guiding surface plays a guiding role, causing the top push rod to move upward, realizing the upward pushing of the top push rod. When the driving rod moves away from the top push rod, the top push rod loses the upward moving force, the belt restores its deformation, presses down the top push rod, and makes the top push rod reset. Then the next driving rod moves to abut against the guiding surface and pushes the top push rod upward again. Repeat the above steps to make the top push rod continuously move up and down, thereby driving the belt to continuously undulate up and down. Description of the Drawings

[0051] Figure 1 It is a schematic structural diagram of the dehydrating agent drying equipment for the preparation of reusable drugs in the embodiment of the present application;

[0052] Figure 2 It is a horizontal cross-sectional view of the reaction tank;

[0053] Figure 3 It is a schematic structural diagram of the conveying conveyor belt;

[0054] Figure 4 It is a schematic structural diagram of the connection relationship between the driving component and the mounting plate;

[0055] Figure 5 It is Figure 4 The enlarged view of part A in

[0056] Figure 6 It is a horizontal cross-sectional view of the receiving plate.

[0057] In the figure: 10, reaction tank; 11, discharge port; 12, guide groove; 13, moving groove; 20, discharge assembly; 21, receiving plate; 211, filter holes; 22, sealing plate; 23, rotating rod; 24, discharge driving member; 241, push plate; 30, drying assembly; 40, conveyor belt; 41, driving wheel; 42, driven wheel; 43, belt; 50, support plate; 60, top push rod; 61, guiding surface; 62, roller; 70, driving assembly; 71, driving conveyor belt; 711, mounting block; 7111, mounting hole; 72, driving rod; 80, feeding mechanism; 81, lifting assembly; 811, mounting plate; 8111, guiding block; 812, lifting driving member; 82, feeding driving member; 821, feeding plate; 90, sealing plate; 110, limiting plate; 120, baffle plate. Detailed implementation mode

[0058] The following is a further detailed description of this application in conjunction with the attached Figures 1-6 drawings.

[0059] An embodiment of this application discloses a dehydrating agent drying device for drug preparation that can be reused. The dehydrating agent for drug preparation can be a dehydrating agent for drug preparation that can be reused such as anhydrous magnesium sulfate or anhydrous sodium sulfate. In this embodiment of the application, anhydrous magnesium sulfate is taken as an example. Referring to Figure 1 and Figure 2 , the dehydrating agent drying device for drug preparation that can be reused includes a reaction tank 10. The top of the reaction tank 10 is provided with a feed port for pouring the solution. The side wall of the reaction tank 10 is provided with a collection port for collecting the solution. The collection port is located at the bottom of the reaction tank 10. The side wall of the reaction tank 10 is penetrated with a discharge port 11. A moving groove 13 is opened on the side wall of the reaction tank 10. The central axis of the moving groove 13 is perpendicular to the central axis of the discharge port 11. The moving groove 13 communicates with the discharge port 11. A sealing plate 90 for blocking the discharge port 11 is inserted in the moving groove 13, and the sealing plate 90 can move in the moving groove 13.

[0060] Referring to Figure 2 and Figure 3 , a drying assembly 30 is provided on the side wall of the reaction tank 10. The drying assembly 30 includes a drying rack and a hot air blower for drying. The drying rack is horizontally arranged above the discharge port 11. The drying rack is welded to the outer side wall of the reaction tank 10. The hot air blower is fixed on the drying rack, and the output end of the hot air blower faces downward.

[0061] Referring to Figure 2 and Figure 3, a conveyor belt 40 is provided directly below the drying rack. The conveyor belt 40 is located below the discharge port 11 and is provided on the outer wall of the reaction tank 10 through a mounting plate 811. The conveyor belt 40 includes a driving wheel 41, a driven wheel 42, and a belt 43. The driving wheel 41 and the driven wheel 42 are vertically arranged and are both rotatably connected to the mounting plate 811 through a rotating rod 23. The driving wheel 41 and the driven wheel 42 are on the same horizontal line. The driving wheel 41 is coaxially fixed with a motor, and the motor is used to drive the driving wheel 41 to rotate. The belt 43 is sleeved on the driving wheel 41 and the driven wheel 42. A support plate 50 is horizontally fixed on the side of the mounting plate 811 away from the reaction tank 10. The support plate 50 is inserted into the belt 43 and is located between the driving wheel 41 and the driven wheel 42.

[0062] Refer to Figure 1 and Figure 3 , two vertically arranged limiting plates 110 are fixed on the mounting plate 811. The limiting plates 110 are located above the belt 43, and the bottom wall of the limiting plate 110 abuts against the top wall of the belt 43. The length of the limiting plate 110 is equal to the width of the belt 43. A vertically arranged baffle 120 is provided outside the reaction tank 10. The top of the baffle 120 is fixedly connected to the drying rack. The side of the belt 43 away from the reaction tank 10 abuts against the side of the baffle 120 close to the reaction tank 10.

[0063] During use, the solution is poured into the reaction tank 10 from the feed port at the top of the reaction tank 10 and contacts the anhydrous magnesium sulfate in the reaction tank 10. The anhydrous magnesium sulfate absorbs the water in the solution and dries the solution. Then, the dried solution flows out of the reaction tank 10 through the collection port and is collected. When the anhydrous magnesium sulfate after absorbing water needs to be dried again, the sealing plate 90 is moved in a direction away from the reaction tank 10 until the sealing plate 90 is completely received in the moving groove 13, that is, the discharge port 11 is in an open state.

[0064] Then, the anhydrous magnesium sulfate after absorbing water is removed from the reaction tank 10 through the discharge port 11. The anhydrous magnesium sulfate is likely to move in a parabolic trajectory. The baffle 120 plays a limiting role, so that the anhydrous magnesium sulfate will not cross the belt 43 until it falls on the belt 43. The gravity of the anhydrous magnesium sulfate exerts a downward pressure on the belt 43, causing the belt 43 between the driving wheel 41 and the driven wheel 42 to sag until the inner wall of the belt 43 abuts against the top wall of the support plate 50. The support plate 50 plays a supporting role, so that the belt 43 will not continue to move downward until it breaks and is damaged.

[0065] At this time, start the hot air blower. The hot air blower transfers heat to the upper surface of the belt 43 and dries the anhydrous magnesium sulfate on the upper surface of the belt 43. During this process, the motor can also be started to make the driving wheel 41 rotate, driving the belt 43 to move, thereby driving the anhydrous magnesium sulfate to continuously move under the hot air blower. The limiting plate 110 restricts the anhydrous magnesium sulfate from sliding out of the belt 43 along with the movement of the belt 43, and finally enables the anhydrous magnesium sulfate to be fully dehydrated.

[0066] Refer to Figure 4 and Figure 5 When the water-absorbed anhydrous magnesium sulfate falls onto the belt 43, in order to prevent the anhydrous magnesium sulfate from easily accumulating on the belt 43, a top push rod 60 is vertically arranged on the support plate 50. The top push rod 60 can be several. The top end of the top push rod 60 is rotatably connected with a roller 62. In the initial state, the roller 62 is flush with the top wall of the support plate 50.

[0067] When the driving wheel 41 is driven to rotate, driving the belt 43 to move, the inner wall of the belt 43 abuts and slides on the roller 62, thereby driving the roller 62 to rotate. That is, the original sliding friction between the belt 43 and the top end of the top push rod 60 becomes rolling friction, reducing the frictional force suffered by the movement of the belt 43. Thus, compared with the belt 43 sliding on the top push rod 60, the belt 43 is not easily damaged by friction, extending the service life of the belt 43 and also making the movement of the belt 43 smoother.

[0068] Refer to Figure 4 and Figure 5 On the side wall of the top push rod 60, a moving block is arranged. On the side wall of the support plate 50, a sliding groove is vertically opened. The moving block is inserted into the sliding groove. A driving component 70 is arranged on the support plate 50. When the driving component 70 is started, it drives the top push rod 60 to move upward, that is, drives the moving block to move in the moving groove 13.

[0069] When the water-absorbed anhydrous magnesium sulfate falls onto the belt 43 and the hot air blower is started, start the motor. The driving wheel 41 rotates, driving the belt 43 to move. At the same time, the driven wheel 42 will also rotate synchronously, making the position of the anhydrous magnesium sulfate on the belt 43 relative to the top push rod 60 move, that is, making the anhydrous magnesium sulfate move to the position of the top push rod 60. Then, use the driving component 70 to move the top push rod 60 upward, so that the roller 62 pushes the part of the belt 43 between the driving wheel 41 and the driven wheel 42 to arch upward. Then move the top push rod 60 downward, and the belt 43 restores its deformation and moves downward closely against the roller 62 until the belt 43 is restored to its original state. Thus, the belt 43 continuously undulates up and down under the action of its own toughness. After long-term use, the belt 43 is easily damaged and needs to be replaced regularly.

[0070] During this process, the anhydrous magnesium sulfate located on the belt 43 is continuously broken up and will not accumulate together, increasing the contact area between the anhydrous magnesium sulfate and heat, enabling the anhydrous magnesium sulfate to be evenly dried. At the same time, the anhydrous magnesium sulfate will also collide and roll over, so that the anhydrous magnesium sulfate on the belt 43 can be fully dried, and thus there will be no phenomenon of only drying the anhydrous magnesium sulfate staring at one place, and the drying is relatively uniform and efficient.

[0071] Refer to Figure 3 and Figure 5 Refer to Figure 3 and Figure 5 , the driving assembly 70 includes a driving conveyor belt 71 and a plurality of driving rods 72. The driving conveyor belt 71 is horizontally arranged. The two driving wheels of the driving conveyor belt 71 are both vertically arranged and on the same horizontal line. The two driving wheels of the driving conveyor belt 71 are both rotatably connected to the support plate 50, and a motor is coaxially fixed on one of the driving wheels. The conveyor belt of the driving conveyor belt 71 is sleeved on the two driving wheels of the driving conveyor belt 71. A plurality of mounting blocks 711 are fixed on the outer side wall of the conveyor belt of the driving conveyor belt 71. The plurality of mounting blocks 711 are evenly arranged along the length direction of the driving conveyor belt 71. A mounting hole 7111 is formed on the side of the mounting block 711 away from the driving conveyor belt 71. One end of the driving rod 72 is inserted into the mounting hole 7111, and the outer wall of the driving rod 72 is threadedly connected to the inner wall of the mounting hole 7111.

[0072] Refer to Figure 5 Refer to Figure 5 , a guiding surface 61 is cut on the side wall of the top push rod 60. The guiding surface 61 is located at the bottom end of the top push rod 60. The bottom end of the guiding surface 61 is inclined in the moving direction of the driving conveyor belt 71. After the water-absorbed anhydrous magnesium sulfate is placed on the belt 43, the belt 43 abuts against the top end of the top push rod 60 under the pressure of the anhydrous magnesium sulfate. Then, the driving conveyor belt 71 is rotated, so that the top end of the driving rod 72 moves to abut against the guiding surface 61 and slides along the guiding surface 61. The guiding surface 61 plays a guiding role, enabling the top push rod 60 to move upward along the direction of the sliding groove, realizing the upward pushing of the top push rod 60. When the driving rod 72 moves to separate from the top push rod 60, the top push rod 60 loses the upward moving force, the belt 43 recovers its deformation, presses down the top push rod 60, and enables the top push rod 60 to reset. Then, the next driving rod 72 moves to abut against the guiding surface 61 and pushes the top push rod 60 upward again. Repeat the above steps, so that the top push rod 60 continuously moves up and down, thereby driving the belt 43 to continuously undulate up and down.

[0073] Refer to Figure 5, in order to adjust the undulating frequency of the belt 43 according to the amount of anhydrous magnesium sulfate on the belt 43, the driving rod 72 can be adjusted in a direction away from the mounting block 711 until the driving rod 72 is withdrawn from the mounting hole 7111, thus realizing the disassembly of the driving rod 72 on the driving conveyor belt 71. At this time, the distance between adjacent driving rods 72 becomes larger, so that the time interval for pushing the top push rod 60 to move upward is longer, and the undulating frequency of the belt 43 is lower. By increasing the driving rods 72 on the driving conveyor belt 71, that is, screwing one end of the driving rod 72 into the mounting hole 7111 to complete the installation of the driving rod 72 on the driving conveyor belt 71, the distance between adjacent driving rods 72 can be changed, so that the time interval for pushing the top push rod 60 to move upward is shorter, and thus the undulating frequency of the belt 43 is higher.

[0074] Refer to Figure 2 and Figure 6 , a discharging assembly 20 is provided on the reaction tank 10. The discharging assembly 20 is used to push anhydrous magnesium sulfate out of the reaction tank 10 from the discharging port 11. The discharging assembly 20 includes a receiving plate 21, a sealing plate 22, a rotating rod 23 and a pushing plate 241. The receiving plate 21 is horizontally installed in the reaction tank 10. The circumferential side wall of the receiving plate 21 is fixedly attached to the inner wall of the reaction tank 10. The top wall of the receiving plate 21 is flush with the bottom wall of the discharging port 11. A circular filtering hole 211 is formed through the receiving plate 21. Optionally, a plurality of filtering holes 211 arranged in a row can also be formed. The sealing plate 22 is inserted into the filtering hole 211. In the initial state, the sealing plate 22 is horizontally arranged, and the circumferential side wall of the sealing plate 22 abuts against the inner wall of the filtering hole 211.

[0075] Refer to Figure 2 and Figure 6 , the rotating rod 23 is horizontally arranged and rotatably connected to the receiving plate 21. One end of the rotating rod 23 extends out of the reaction tank 10. The rotating rod 23 is fixedly connected to the sealing plate 22 and is located on the extension line of the diameter of the sealing plate 22. The reaction tank 10 is fixedly provided with a discharging driving member 24 by bolts. In the embodiment of the present application, the discharging driving member 24 is a cylinder. The output end of the discharging driving member 24 is fixedly provided with a vertically arranged pushing plate 241. The pushing plate 241 is located inside the reaction tank 10, and the bottom wall of the pushing plate 241 abuts against the top wall of the receiving plate 21. The discharging driving member 24 drives the pushing plate 241 to move on the receiving plate 21 in a direction close to or away from the discharging port 11.

[0076] During use, insert the sealing plate 90 into the moving groove 13 and move it in the moving groove 13 until one side of the sealing plate 90 perpendicular to the moving direction of the sealing plate 90 abuts against the inner wall of the discharge port 11, so that the sealing plate 90 blocks the discharge port 11 and restricts the movement of anhydrous magnesium sulfate out of the reaction tank 10 from the discharge port 11. Then the solution is poured into the reaction tank 10 through the feed port. In the initial state, the sealing plate 22 blocks the filter holes 211, that is, the filter holes 211 are in a closed state, so that the solution is blocked above the receiving plate 21 by the receiving plate 21 and contacts the anhydrous magnesium sulfate on the receiving plate 21. The anhydrous magnesium sulfate absorbs the moisture in the solution and dries the solution.

[0077] Then drive the rotating rod 23 to rotate, drive the sealing plate 22 to rotate, so that the side wall of the sealing plate 22 is separated from the inner wall of the filter hole 211, so that a gap appears between the sealing plate 22 and the inner wall of the filter hole 211, that is, the filter hole 211 is in an open state. The dried solution leaks out of the receiving plate 21 through the filter hole 211 and deposits at the bottom of the reaction tank 10 for storage. Finally, open the collection port, and the dried solution flows out of the reaction tank 10 and is collected.

[0078] When the anhydrous magnesium sulfate needs to be dried again, start the discharge driving member 24, drive the push plate 241 to move on the receiving plate 21 in the direction close to the discharge port 11, so as to push the water-absorbed anhydrous magnesium sulfate on the receiving plate 21 out of the reaction tank 10 from the discharge port 11. The anhydrous magnesium sulfate falls onto the belt 43 for drying for the next use.

[0079] Refer to Figure 2 , when the anhydrous magnesium sulfate on the belt 43 is dried, it needs to be sent back into the reaction tank 10 for the next drying of the solution. A feeding mechanism 80 is provided on the reaction tank 10. The feeding mechanism 80 includes a lifting assembly 81 and a feeding driving member 82. The feeding driving rod 72 is fixed to the baffle 120 by bolts. In the embodiment of the present application, the feeding driving member 82 adopts a cylinder. The output end of the feeding driving member 82 is fixed with a feeding plate 821 and is aligned with the discharge port 11. The feeding driving member 82 can drive the feeding plate 821 to move horizontally, and the feeding plate 821 can pass through the discharge port 11.

[0080] Refer to Figure 1 and Figure 3, the lifting assembly 81 includes a lifting drive 812. The lifting drive 812 is fixed to the outer sidewall of the reaction tank 10 by bolts. In the embodiment of the present application, the lifting drive 812 is a cylinder and is located below the belt 43. The output end of the lifting drive 812 faces upward and is fixed to the mounting plate 811. The lifting drive 812 drives the mounting plate 811 to move up and down. To increase the stability of the movement of the mounting plate 811, a guiding block 8111 is integrally formed on the side of the mounting plate 811 close to the reaction tank 10. A guiding groove 12 is formed in the outer sidewall of the reaction tank 10 in the vertical direction. The guiding block 8111 is inserted into the guiding groove 12. When the lifting drive moves the mounting plate 811, the guiding block 8111 moves in the guiding groove 12, and the inner wall of the guiding groove 12 abuts against the sidewall of the guiding block 8111, which plays a role in restricting and guiding the guiding block 8111, so that the mounting plate 811 can only move along the vertical direction and is not prone to deviation.

[0081] When the anhydrous magnesium sulfate after absorbing water is dried on the belt 43, the lifting drive 812 is started to push the mounting plate 811 upward until the belt 43 moves to align with the discharge port 11. At this time, the top wall of the belt 43 is higher than the bottom wall of the discharge port 11, and the top wall of the belt 43 and the bottom wall of the feeding plate 821 are on the same plane. Then the feeding drive 82 is started to drive the feeding plate 821 to move towards the reaction tank 10, so that the feeding plate 821 pushes the anhydrous magnesium sulfate dried on the belt 43 into the reaction tank 10 through the discharge port 11. The anhydrous magnesium sulfate falls onto the receiving plate 21 and accumulates. The feeding plate 821 continues to move, so as to push the part of the accumulated anhydrous magnesium sulfate higher than the belt 43 away from the belt 43, playing a leveling role, so that the dried anhydrous magnesium sulfate is evenly laid on the receiving plate 21, which is convenient for the next drying.

[0082] The implementation principle of a dehydrating agent drying device for drug preparation that can be reused in the embodiment of the present application is as follows: during use, the anhydrous magnesium sulfate after absorbing water is placed on the belt 43. The gravity of the anhydrous magnesium sulfate exerts a downward pressure on the belt 43, causing the belt 43 between the driving wheel 41 and the driven wheel 42 to sag until the inner wall of the belt 43 abuts against the top wall of the support plate 50. The support plate 50 plays a supporting role. In the initial state, the roller 62 is flush with the top wall of the support plate 50.

[0083] Next, start the drying component 30 to dissipate heat onto the belt 43. Start the motor to make the driving wheel 41 rotate, driving the belt 43 to move. As a result, the position of the anhydrous magnesium sulfate on the belt 43 relative to the ejector rod 60 changes, that is, the anhydrous magnesium sulfate moves to the position of the ejector rod 60. Then, move the ejector rod 60 upward so that the top end of the ejector rod 60 pushes the part of the belt 43 between the driving wheel 41 and the driven wheel 42 to deform and arch upward. Then, move the ejector rod 60 downward, and the belt 43 resumes its deformation and moves downward closely against the roller 62 until the belt 43 is restored to its original state, causing the belt 43 to continuously undulate up and down.

[0084] During this process, the anhydrous magnesium sulfate on the belt 43 is continuously dispersed and will not accumulate together, increasing the contact area between the anhydrous magnesium sulfate and the heat, enabling the anhydrous magnesium sulfate to be evenly dried. At the same time, the anhydrous magnesium sulfate will also collide and tumble with each other, so that the anhydrous magnesium sulfate on the belt 43 can be fully dried. Furthermore, there will be no phenomenon of only drying the anhydrous magnesium sulfate at a fixed point. The drying is relatively uniform and efficient.

[0085] The above are all the preferred embodiments of this application. The protection scope of this application is not limited accordingly. Therefore, all equivalent changes made according to the structure, shape, and principle of this application should be covered within the protection scope of this application.

Claims

1. A dehydrating agent drying device for drug preparation that can be reused, characterized in that, Comprising: A reaction tank (10), with a discharge port (11) penetrating through the side wall of the reaction tank (10); A discharge assembly (20), arranged on the reaction tank (10) for sending the dehydrating agent absorbed with water in the reaction tank (10) out from the discharge port (11); A conveying conveyor belt (40), arranged on the outer side wall of the reaction tank (10) and located below the discharge port (11). The conveying conveyor belt (40) includes a driving wheel (41), a driven wheel (42) and a belt (43). The driving wheel (41) and the driven wheel (42) are arranged on the reaction tank (10), and the belt (43) is sleeved on the driving wheel (41) and the driven wheel (42). The belt (43) is used to receive the dehydrating agent moved out from the discharge port (11); A drying assembly (30), arranged on the outer side wall of the reaction tank (10) for drying the dehydrating agent on the belt (43); A support plate (50), horizontally arranged on the outer side wall of the reaction tank (10). The support plate (50) is inserted into the belt (43) and located between the driving wheel (41) and the driven wheel (42); A top push rod (60), slidably connected to the support plate (50), and the top push rod (60) abuts against the belt (43); A driving assembly (70), arranged on the support plate (50), and the driving assembly (70) is used to drive the top push rod (60) to lift the belt.

2. The dehydrating agent drying equipment for reusable drug preparation according to claim 1, characterized in that, The driving assembly (70) includes: A driving conveyor belt (71), horizontally arranged below the top push rod (60), and the driving conveyor belt (71) is rotatably connected to the support plate (50); A plurality of driving rods (72), arranged on the outer side wall of the driving conveyor belt (71). A guiding surface (61) for abutting against the driving rods (72) is arranged at the bottom of the top push rod (60). One end of the guiding surface (61) close to the driving conveyor belt (71) is inclined in the moving direction of the driving conveyor belt (71).

3. The dehydrating agent drying device for preparing reusable drugs according to claim 2, characterized in that, A plurality of mounting blocks (711) are fixed on the outer wall of the driving conveyor belt (71). The plurality of mounting blocks (711) are arranged along the length direction of the driving conveyor belt (71). A mounting hole (7111) is opened on the side of the mounting block (711) away from the driving conveyor belt (71). One end of the driving rod (72) is threadedly connected to the inner wall of the mounting hole (7111).

4. The dehydrating agent drying device for reusable drug preparation according to claim 1, characterized in that, A roller (62) is rotatably connected to the top end of the top push rod (60), and the roller (62) abuts against the side of the belt (43) in contact with the driving wheel (41) and the driven wheel (42).

5. The dehydrating agent drying device for reusable drug preparation according to claim 1, characterized in that, A limiting plate (110) is provided above the belt (43), and the limiting plate (110) is used to limit the dehydrating agent from sliding off the belt (43) from the end of the belt (43) in the length direction. The limiting plate (110) is provided on the outer wall of the reaction box (10), and a baffle (120) is fixed on the outer wall of the reaction box (10). The baffle (120) is vertically arranged, and the side of the belt (43) away from the reaction box (10) is in contact with the baffle (120), and the baffle (120) extends upward to the discharge port (11).

6. The dehydrating agent drying device for reusable drug preparation according to claim 1, characterized in that, The discharging assembly (20) comprises: A receiving plate (21), the receiving plate (21) being horizontally mounted in the reaction box (10), the circumferential side wall of the receiving plate (21) being abutted and fixed against the inner wall of the reaction box (10), the top wall of the receiving plate (21) being flush with the bottom wall of the discharge port (11), and a filtering hole (211) being formed through the receiving plate (21); A sealing plate (22) is disposed in the filter hole (211) and can block the filter hole (211); a rotating rod (23), the rotating rod (23) being arranged horizontally and rotatably connected to the receiving plate (21), one end of the rotating rod (23) extending out of the reaction box (10), the rotating rod (23) being fixedly connected to the sealing plate (22) and used for driving the sealing plate (22) to rotate; A push plate (241), the bottom wall of which is in contact with the top wall of the receiving plate (21), a discharge driving member (24) is provided on the side wall of the reaction box (10), the output end of which is fixed with the push plate (241), and the discharge driving member (24) can drive the push plate (241) to move on the receiving plate (21) towards or away from the discharge port (11).

7. The dehydrating agent drying device for reusable drug preparation according to claim 5, wherein The reaction box (10) is provided with a feeding mechanism (80), and the feeding mechanism (80) is used to feed the dried dehydrating agent back to the reaction box (10). The feeding mechanism (80) comprises: A lifting assembly (81), the lifting assembly (81) being arranged on the reaction box (10) and used for driving the conveyor belt (40) to move up and down; A feeding drive member (82), wherein the feeding drive member (82) is arranged on the baffle (120), a feeding plate (821) is fixed to the output end of the feeding drive member (82), and the feeding drive member (82) drives the feeding plate (821) to move horizontally and can penetrate a discharge port (11).

8. The dehydrating agent drying device for preparing reusable drugs according to claim 7, characterized in that, The lifting assembly (81) comprises: A mounting plate (811), wherein the mounting plate (811) is slidably connected to the outer side wall of the reaction box (10), the driving wheel (41) and the driven wheel (42) are rotatably connected to a side of the mounting plate (811) away from the reaction box (10), and the limiting plate (110) and the supporting plate (50) are both fixed to the mounting plate (811); A lifting driving member (812), the lifting driving member (812) is fixedly arranged on the outer side wall of the reaction tank (10), the output end of the lifting driving member (812) is vertically upward and is fixed to the mounting plate (811), and the lifting driving member (812) drives the mounting plate (811) to move up and down.

9. The dehydrating agent drying device for preparing reusable drugs according to claim 8, wherein, A guiding block (8111) is fixed on the side wall of the mounting plate (811), a guiding groove (12) is formed in the outer side wall of the reaction tank (10) in the vertical direction, and the guiding block (8111) is inserted into the guiding groove (12) and can move in the guiding groove (12).

10. The dehydrating agent drying device for reusable drug preparation according to claim 1, characterized in that, A moving groove (13) is formed in the side wall of the reaction tank (10), the central axis of the moving groove (13) is perpendicular to the central axis of the discharge port (11), the moving groove (13) is communicated with the discharge port (11), a sealing plate (90) for blocking the discharge port (11) is inserted into the moving groove (13), and the sealing plate (90) can move in the moving groove (13).

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