An oxygenator lower cover structure, an oxygenator housing and an oxygenator

Abstract

The embodiment of the application provides an oxygenator lower cover structure, an oxygenator shell and an oxygenator, the lower cover body is provided with a first chamber, the first chamber is provided with a first isolation ring, a second isolation ring and a plurality of rib structures; the second isolation ring is peripherally arranged outside the first isolation ring, and the plurality of rib structures are peripherally arranged outside the second isolation ring; the liquid inlet pipe penetrates the side wall of the lower cover body and the second isolation ring from outside to inside in sequence, the liquid inlet pipe is communicated with the passage between the first isolation ring and the second isolation ring, one end of the liquid inlet pipe is arranged on the second isolation ring, the exhaust pipe is arranged on the side wall of the lower cover body, and the exhaust pipe is communicated with the passage between the side wall of the lower cover body and the second isolation ring; the liquid inlet pipe and the exhaust pipe are arranged on the same side and parallel to each other, and the exhaust port is arranged in the intermediate region of the liquid inlet pipe and the exhaust pipe, so that the oxygenation efficiency of the oxygenator is improved.

Description

Technical Field

[0001] This application relates to the field of extracorporeal membrane oxygenation (ECMO) technology, and in particular to an oxygenator lower cover structure, an oxygenator shell, and an oxygenator. Background Technology

[0002] Extracorporeal membrane oxygenation (ECMO) involves drawing blood from outside the body, oxygenating it through a specially designed artificial heart-lung bypass, and then injecting it into the patient's arterial or venous system. This partially replaces the function of the heart and lungs, maintaining oxygenated blood supply to the body's organs and tissues. The oxygenator is a crucial component of the ECMO system, responsible for maintaining the temperature of the blood outside the body and performing blood oxygenation. It operates through three main circulatory pathways: the blood pathway, where blood enters the oxygenator through specific channels and is warmed by the temperature-controlled membrane to maintain a constant blood temperature; the gas pathway, where oxygen permeates into the blood through the oxygenation membrane wires in the oxygenation area, while carbon dioxide from the venous blood permeates into the oxygenation membrane wires and is released from the blood; and the water pathway, where a constant-temperature liquid provides heat to the blood through the temperature-controlled membrane wires, maintaining the blood's temperature within the extracorporeal circulation system.

[0003] The existing oxygenator gas path design is not conducive to improving oxygenation efficiency. Therefore, without changing the blood and water paths, how to improve the oxygenation efficiency of the gas path is a technical problem that needs to be solved. Summary of the Invention

[0004] In order to solve or alleviate all or part of the above problems, the present application provides an oxygenator lower cover structure, an oxygenator shell, and an oxygenator that facilitate the discharge of blood and gas.

[0005] In a first aspect, embodiments of this application provide an oxygenator lower cover structure, including: a lower cover body, an inlet pipe, an exhaust pipe, and an exhaust port;

[0006] The lower cover body is provided with a first chamber, and the first chamber is provided with a first isolation ring, a second isolation ring and a plurality of rib structures;

[0007] The second isolation ring is spaced out around the first isolation ring, and the plurality of the rib structures are spaced out around the second isolation ring;

[0008] The inlet pipe passes through the side wall of the lower cover body and the second isolation ring from the outside to the inside. The inlet pipe is connected to the channel between the first isolation ring and the second isolation ring. One end of the inlet pipe is located on the second isolation ring. The exhaust pipe is connected to the channel between the side wall of the lower cover body and the second isolation ring. One end of the exhaust pipe is located on the side wall of the lower cover body.

[0009] The inlet pipe and the outlet pipe are arranged parallel to each other and on the same side, and the outlet is located in the middle area between the inlet pipe and the outlet pipe.

[0010] In a preferred embodiment of this application, the diameter of the lower cover body where the exhaust port is located is perpendicular to the liquid inlet pipe and the exhaust pipe, respectively.

[0011] In a preferred embodiment of this application, the shortest distance from the exhaust port to the center of the lower cover body is the first distance, and the perpendicular distance between the exhaust port and the tangent of the lower cover body is the second distance, wherein the first distance is greater than the second distance.

[0012] In a preferred embodiment of this application, a plurality of the rib structures are vertically arranged in the first chamber, the plurality of rib structures have the same height, and the height of the plurality of rib structures is lower than the side wall height of the lower cover body and the height of the second isolation ring.

[0013] In a preferred embodiment of this application, two adjacent rib structures are not connected end to end and are spaced apart.

[0014] In a preferred embodiment of this application, one end of each rib structure is connected to the side wall of the lower cover body, and the other end of each rib structure is at a predetermined distance from the side wall of the lower cover body.

[0015] In a preferred embodiment of this application, a rib structure is symmetrically distributed on both sides of the liquid inlet pipe.

[0016] In a preferred embodiment of this application, the air inlet of the exhaust pipe has a predetermined distance from the other end of its adjacent rib structure.

[0017] In a preferred embodiment of this application, the liquid inlet pipe is arranged radially along the lower cover body, and the liquid inlet pipe and the vent pipe are arranged on the horizontal plane where the lower cover body is located.

[0018] Compared with the prior art, this application provides an oxygenator lower cover structure, including: a lower cover body, an inlet pipe, an exhaust pipe, and an exhaust port; the lower cover body is provided with a first chamber, in which a first isolation ring, a second isolation ring, and multiple rib structures are provided; the second isolation rings are spaced apart around the first isolation rings, and the multiple rib structures are spaced apart around the second isolation rings; the inlet pipe passes through the side wall of the lower cover body and the second isolation rings sequentially from the outside to the inside, the inlet of the inlet pipe is connected to the channel between the first and second isolation rings, one end of the inlet pipe is located on the second isolation ring, the exhaust pipe is located on the side wall of the lower cover body, the inlet of the exhaust pipe is connected to the channel between the side wall of the lower cover body and the second isolation rings; the inlet pipe and the exhaust pipe are arranged parallel to each other and on the same side, and the exhaust port is located in the middle area of ​​the inlet pipe and the exhaust pipe. The lower cover structure provided by this application facilitates the removal of carbon dioxide after blood oxygenation, thus improving the oxygenation efficiency of the oxygenator.

[0019] In a second aspect, embodiments of this application also provide an oxygenator housing, including an upper cover structure, a housing body, and the oxygenator lower cover structure described in the first aspect. The upper cover structure includes an upper cover body, an inlet tube, a drain tube, and an air inlet tube.

[0020] The upper cover structure and the lower cover structure are disposed at both ends of the housing body;

[0021] The upper cover body is provided with a second chamber, and the second chamber is provided with a third isolation ring and a fourth isolation ring; the inlet blood vessel passes through the third isolation ring and the fourth isolation ring from the outside to the inside, and the space enclosed by the inlet blood vessel and the fourth isolation ring is connected;

[0022] The drain pipe is connected to the channel between the third and fourth isolation rings, and the air inlet pipe is connected to the channel between the side wall of the upper cover body and the third isolation ring;

[0023] The drain pipe and the inlet pipe are parallel to each other and in the same direction, and the air inlet pipe and the exhaust pipe are parallel to each other and in the same direction;

[0024] The inlet tube is perpendicular to the drain pipe and the air inlet pipe respectively. The drain pipe and the air inlet pipe are parallel to each other and on the same side. The inlet tube, the drain pipe and the air inlet pipe are arranged on the horizontal plane where the upper cover body is located.

[0025] An outlet vessel is provided on the oxygenator housing at a position corresponding to the inlet vessel. The outlet vessel and the inlet vessel are located on the same side and are arranged parallel to each other.

[0026] In a preferred embodiment of this application, the outlet blood vessel is disposed at the end of the housing body near the lower cover structure.

[0027] In a preferred embodiment of this application, the drain pipe is disposed between the inlet pipe and the air inlet pipe.

[0028] The beneficial effects provided by the second aspect are the same as those of the first aspect compared to the existing technology, and will not be repeated here.

[0029] Thirdly, embodiments of this application also provide an oxygenator, including the oxygenator housing described in the second aspect.

[0030] Compared with existing technologies, the device provided by the third aspect defines the specific regional layout and flow radial direction of the three paths (gas path, water path, or blood path) in the cover and shell of the oxygenator. This layout and the approximately radial flow of the three paths result in better oxygenation effect and reduced thrombus formation. Attached Figure Description

[0031] Figure 1 A perspective view of the internal structure of the lower cover of a membrane oxygenator provided in this application embodiment;

[0032] Figure 2 A perspective view of the external structure of the lower cover of a membrane oxygenator provided in this application embodiment;

[0033] Figure 3 A perspective view of a membrane oxygenator shell structure provided in an embodiment of this application;

[0034] Figure 4 A perspective view of the internal structure of a membrane oxygenator cover provided in this application embodiment;

[0035] Figure 5 This is a perspective view of the external structure of a membrane oxygenator cover structure provided in an embodiment of this application. Detailed Implementation

[0036] To enable those skilled in the art to better understand the technical solutions of this application, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort should fall within the scope of protection of this application.

[0037] It should be noted that the terms "first," "second," etc., in the specification, claims, and accompanying drawings of this application are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of this application described herein can be implemented in orders other than those illustrated or described herein. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus.

[0038] In this application, the oxygenator is one of the devices in an extracorporeal oxygenation system. It can oxygenate venous blood into arterial blood and remove carbon dioxide from the blood to complete the gas exchange of blood outside the body.

[0039] The existing oxygenator cover is not conducive to the discharge of gas after exchange, nor is it conducive to the discharge of condensate from the heated gas in the gas path. Therefore, in order to solve the problems in the prior art, this application proposes the following technical solution.

[0040] Firstly, such as Figure 1 and Figure 2 As shown, this application provides an oxygenator lower cover structure, which includes: a lower cover body 01, an inlet pipe 06, an exhaust pipe 07, and an exhaust port 05;

[0041] The lower cover body 01 is provided with a first chamber, and the first chamber is provided with a first isolation ring 04, a second isolation ring 03 and a plurality of rib structures 02;

[0042] The second isolation ring 03 is spaced out around the first isolation ring 04, and a plurality of the rib structures 02 are spaced out around the second isolation ring 03;

[0043] The liquid inlet pipe 06 passes through the side wall of the lower cover body 01 and the second isolation ring 03 from the outside to the inside. The liquid inlet pipe 06 communicates with the channel between the first isolation ring 04 and the second isolation ring 03. One end of the liquid inlet pipe 06 is set on the second isolation ring 03. The exhaust pipe 07 is set on the side wall of the lower cover body 01. The exhaust pipe 07 communicates with the channel between the side wall of the lower cover body 01 and the second isolation ring 03.

[0044] The liquid inlet pipe 06 and the exhaust pipe 07 are arranged parallel to each other and on the same side, and the exhaust port 05 is located in the middle area between the liquid inlet pipe 06 and the exhaust pipe 07.

[0045] In this embodiment, multiple rib structures 02 are provided to dissipate heat and guide airflow. The carbon dioxide to be discharged is dissipated and guided by the multiple rib structures 02 so that it can be discharged from the exhaust pipe 07. In this embodiment, seven rib structures 02 are preferably provided.

[0046] The diameter of the lower cover body 01 where the exhaust port 05 is located is perpendicular to the liquid inlet pipe 06 and the exhaust pipe 07, respectively.

[0047] In this embodiment of the application, the shortest distance from the exhaust port 05 to the center of the lower cover body 01 is the first distance, and the perpendicular distance between the exhaust port 05 and the tangent of the lower cover body 01 is the second distance. The first distance is greater than the second distance.

[0048] The location design of the exhaust port 05 has been experimentally verified. The locations of exhaust ports B1 / B2 / B3 are only examples in this embodiment. For example, under different oxygen flow rates, the total CO2 removal and total O2 exchange of the exhaust ports located at B1 / B2 / B3 were measured. It was found that the gas exchange related data at B1 was significantly higher than those at B2 and B3. Since condensate will be generated at the outlet of the gas path of the entire oxygenator when it is cooled, the exhaust port 05 can also discharge the condensate generated at the outlet of the gas path.

[0049] In this embodiment, the upper and lower cover structures of the oxygenator are concentrically arranged, and the cross-sections of the upper and lower cover structures are circular. In specific use, a temperature-changing membrane filament is provided between the first isolation ring 04 and the second isolation ring 03. One end of the temperature-changing membrane filament is connected to the space between the third isolation ring 12 and the fourth isolation ring 13 of the upper cover body, and the other end of the temperature-changing membrane filament is connected to the space between the first isolation ring 04 and the second isolation ring 03 of the lower cover body. A heat exchange medium, such as water, flows through the annular temperature-changing region formed by numerous temperature-changing membrane filaments. The heat exchange medium enters the temperature-changing membrane region channel between the first isolation ring 04 and the second isolation ring 03 through the inlet pipe 06, and flows out from the drain pipe 10 that communicates with the space between the third isolation ring 12 and the fourth isolation ring 13 of the upper cover body, so as to heat and keep the blood warm. Similarly, the arrangement of the variable temperature membrane filaments, with the oxygenation membrane filaments distributed on the outside of the variable temperature region, forms a ring-shaped oxygenation region. High-purity oxygen flows from the side wall of the upper cover body 09 and the space of the fourth isolation ring 13 of the upper cover body, through the oxygenation membrane filaments, through the side wall of the lower cover body 01 and the space of the second isolation ring 03 of the lower cover body, and then is discharged through the exhaust pipe 07.

[0050] In a preferred embodiment of this application, after blood flows from the inlet vessel 08 into the area inside the third isolation ring 12 of the upper cover body 09, a diversion structure can be present in the central region of the housing body, the area inside the first isolation ring 04 of the lower cover body 01, and the central region inside the third isolation ring 12 of the upper cover body 09 to disperse the blood flow, as described in patent CN115554505A. The blood is dispersed in all directions through the diversion structure, passing sequentially through the temperature-changing membrane filament region and the oxygenation membrane filament region, and finally flowing out from the outlet vessel on the housing body. Adding a diversion structure has the advantages of better blood dispersion and reduced oxygenator pre-filling volume. For example, the cavity-type diversion structure in patent CN115554505A also facilitates the fixing of the oxygenator during use.

[0051] In a preferred embodiment of this application, a plurality of the rib structures 02 are vertically arranged in the first chamber. Each rib structure 02 is elongated and of the same height, and all rib structures 02 are lower than the side wall height of the lower cover body 01 and the height of the second isolation ring 03. In this embodiment, the rib structures 02 are vertically arranged in the first chamber because this allows for a larger contact area between the carbon dioxide gas discharged after blood oxygenation and the rib structures 02, which is beneficial for the guiding effect of the rib structures 02. The rib structures 02 can make the carbon dioxide flow more evenly and quickly to the exhaust pipe 07 and the exhaust port 05. This "flow stabilization" effect is more conducive to the flow of oxygen throughout the oxygenator, resulting in better oxygenation efficiency.

[0052] In a preferred embodiment of this application, two adjacent rib structures 02 are not connected end to end and are spaced apart. By not connecting end to end and spaced apart, it is beneficial to guide and discharge the oxygenated gas.

[0053] As a preferred embodiment of this application, one end of each rib structure 02 is connected to the side wall of the lower cover body 01, and the other end of each rib structure 02 is at a preset distance from the side wall of the lower cover body 01, so that the gas can form a rotating flow along the rib direction and be discharged to the outlet more smoothly and faster, avoiding the retention of gas after exchange.

[0054] In a preferred embodiment of this application, a rib structure 02 is symmetrically distributed on both sides of the liquid inlet pipe 06. The symmetrical distribution of the rib structure 02 on both sides of the liquid inlet pipe 06 facilitates gas flow guidance on both sides of the liquid inlet pipe 06.

[0055] In a preferred embodiment of this application, the exhaust pipe 07 is spaced at a predetermined distance from the other end of its adjacent rib structure 02, and the liquid inlet pipe 06 is parallel to the exhaust pipe 07 and disposed on the same side. The predetermined distance between the exhaust pipe 07 and the other end of its adjacent rib structure 02 is used to facilitate better exhaust.

[0056] Preferably, the liquid inlet pipe 06 is arranged radially along the lower cover body 01.

[0057] Secondly, such as Figure 3 As shown, this application provides an oxygenator housing, including the oxygenator lower cover structure, upper cover structure and oxygenator housing 14 as described in the first aspect, wherein the upper cover structure and the lower cover structure are disposed at both ends of the housing body 14;

[0058] like Figure 4 and Figure 5 As shown, the upper cover structure includes an upper cover body 09, an inlet tube 08, a drain tube 10, and an air inlet tube 11;

[0059] The upper cover body 09 is provided with a second chamber, in which a third isolation ring 12 and a fourth isolation ring 13 are provided; the inlet blood vessel 08 passes through the third isolation ring 12 and the fourth isolation ring 13 sequentially from the outside to the inside, and the space enclosed by the inlet blood vessel 08 and the fourth isolation ring 13 is connected.

[0060] The drain pipe 10 is connected to the channel between the third isolation ring 12 and the fourth isolation ring 13. The channel between the third isolation ring 12 and the fourth isolation ring 13 is a channel for the flow of heat exchange medium, which is water. The side wall of the upper cover body 09 is connected to the third isolation ring 12 as a channel for gas flow, which is oxygen. The space enclosed by the inlet blood vessel 08 and the fourth isolation ring 13 is a channel for blood flow.

[0061] The drain pipe 10 and the inlet pipe 06 are parallel to each other and in the same direction, and the air inlet pipe 11 and the exhaust pipe 07 are parallel to each other and in the same direction.

[0062] The inlet tube 08 is perpendicular to the drain tube 10 and the air inlet tube 11 respectively. The drain tube 10 and the air inlet tube 07 are parallel to each other and on the same side. The inlet tube 08, the drain tube 10 and the air inlet tube 07 are arranged on the horizontal plane of the upper cover body 09. An outlet tube 15 is provided on the oxygenator housing 14 at the position corresponding to the inlet tube 08. The outlet tube 15 is arranged on the same side and parallel to the inlet tube 08.

[0063] In a preferred embodiment of this application, the outlet blood vessel 08 is disposed at the end of the housing body 14 near the lower cover structure.

[0064] In a preferred embodiment of this application, the drain pipe 10 is disposed between the inlet pipe 08 and the air inlet pipe 11.

[0065] By coordinating the positions of the drain pipe 10 and air inlet pipe 11 on the upper cover structure with the exhaust pipe 07 and drain pipe 06 on the lower cover structure of the oxygenator, the oxygenation efficiency of the oxygenator for blood can be improved. After testing, it was found that the oxygenation efficiency of the blood is better when the air inlet pipe 11 is set at position T3 than when it is set at positions T1, T2 and T4.

[0066] Compared with the prior art, the beneficial effects of the technical solution provided in the second aspect are the same as those in the first aspect, and will not be repeated here.

[0067] Thirdly, embodiments of this application also provide an oxygenator, including the oxygenator housing described in the second aspect.

[0068] Compared with the prior art, the beneficial effects of the device provided by the third aspect are the same as those of the first aspect, and will not be repeated here.

[0069] Thirdly, embodiments of this application also provide an oxygenator, including the oxygenator housing described in the second aspect.

[0070] Although the present invention has been described in detail herein with general descriptions and specific embodiments, modifications or improvements can be made to it, which will be obvious to those skilled in the art. Therefore, all such modifications or improvements made without departing from the spirit of the present invention fall within the scope of protection claimed by the present invention.

Claims

1. An oxygenator lower cover structure, characterized by, The oxygenator comprises: a lower cover body, a liquid inlet pipe, an exhaust pipe and an exhaust port; a first cavity is arranged on the lower cover body, and a first isolation ring, a second isolation ring and a plurality of rib structures are arranged in the first cavity; the second isolation ring is arranged peripherally between the first isolation ring, and the plurality of rib structures are arranged peripherally between the second isolation ring; the liquid inlet pipe penetrates the sidewall of the lower cover body and the second isolation ring from outside to inside in sequence, one end of the liquid inlet pipe is arranged on the second isolation ring, and the liquid inlet pipe is in communication with a passage between the first isolation ring and the second isolation ring; one end of the exhaust pipe is arranged on the sidewall of the lower cover body, and the exhaust pipe is in communication with a passage between the sidewall of the lower cover body and the second isolation ring; the liquid inlet pipe and the exhaust pipe are arranged in parallel and on the same side, and the exhaust port is arranged in the middle region of the liquid inlet pipe and the exhaust pipe.

2. An oxygenator lower cover structure as claimed in claim 1, wherein, The diameter of the lower cover body where the exhaust port is arranged is perpendicular to the liquid inlet pipe and the exhaust pipe.

3. An oxygenator lower cover structure as claimed in claim 2, wherein The shortest distance from the exhaust port to the center of the lower cover body is a first distance, and the vertical distance between the tangent lines of the exhaust port is a second distance, and the first distance is greater than the second distance.

4. An oxygenator lower cover structure as in claim 1, wherein, The plurality of rib structures are arranged vertically in the first cavity, the heights of the plurality of rib structures are the same, and the heights of the plurality of rib structures are lower than the height of the sidewall of the lower cover body and the height of the second isolation ring.

5. An oxygenator lower cover structure as in claim 1, wherein, Two adjacent rib structures are not connected at their ends and are arranged at intervals.

6. An oxygenator lower cover structure as in claim 1, wherein, One end of each rib structure is connected to the sidewall of the lower cover body, and the other end of each rib structure has a preset distance from the sidewall of the lower cover body.

7. An oxygenator lower cover structure as in claim 1, wherein, A rib structure is symmetrically arranged on both sides of the liquid inlet pipe.

8. An oxygenator lower cover structure as in claim 1, wherein, The gas inlet of the exhaust pipe has a preset distance from the other end of the adjacent rib structure.

9. An oxygenator lower cover structure as in claim 1, wherein, The liquid inlet pipe is arranged along the radial direction of the lower cover body.

10. An oxygenator housing, characterized by, The oxygenator comprises: an upper cover structure, a shell body and the lower cover structure of the oxygenator according to any one of claims 1 to 9, the upper cover structure comprises an upper cover body, a blood inlet pipe, a liquid outlet pipe and a gas inlet pipe; the upper cover structure and the lower cover structure are arranged at two ends of the shell body; a second cavity is arranged on the upper cover body, and a third isolation ring and a fourth isolation ring are arranged in the second cavity; the blood inlet pipe penetrates the third isolation ring and the fourth isolation ring from outside to inside in sequence, and the blood inlet pipe is in communication with a space surrounded by the fourth isolation ring; the liquid outlet pipe is in communication with a passage between the third isolation ring and the fourth isolation ring, and the gas inlet pipe is in communication with a passage between the sidewall of the upper cover body and the third isolation ring; the liquid outlet pipe and the liquid inlet pipe are arranged in parallel and in the same direction, and the gas inlet pipe and the exhaust pipe are arranged in parallel and in the same direction; the blood inlet pipe is arranged vertically to the liquid outlet pipe and the gas inlet pipe, the liquid outlet pipe and the gas inlet pipe are arranged in parallel and on the same side, and the blood inlet pipe, the liquid outlet pipe and the gas inlet pipe are arranged on a horizontal plane where the upper cover body is arranged; 11. An oxygenator housing as claimed in claim 10, wherein, a blood outlet pipe is arranged on the oxygenator shell body at a position corresponding to the blood inlet pipe, and the blood outlet pipe is arranged on the same side as the blood inlet pipe and in parallel with the blood inlet pipe. The blood outlet pipe is arranged at an end of the shell body close to the lower cover structure.

12. An oxygenator housing as claimed in claim 10, wherein, The drain tube is disposed between the blood inlet tube and the gas inlet tube.

13. An oxygenator characterized by, The oxygenator housing according to any one of claims 10 to 12.

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