An insecticide composition

Abstract

The present invention relates to an insecticidal composition, which contains active ingredients Compound I and Compound II, wherein Compound II is selected from at least one of spinosad, spinetoram, bromofenac, thiobencarb, sulfoxaflor, emamectin benzoate, cypermethrin, ethoprolin, and bifenthrin. The present invention also relates to the use of the insecticidal composition for preventing or controlling pests of the families Plutella xylostella, Tortricidae, Noctuidae, Delphacidae, Aleyrodidae, Tetranychus, Thripidae, Aphididae, and Cyprinococcidae. Compound I.

Description

[0001] This application is a divisional application for the patent number "2020106269426" applied by the applicant on July 2, 2020, and the patent name is "A pesticidal composition". Technical Field

[0002] The present invention relates to an insecticidal composition which is particularly effective in controlling agricultural and forestry pests. Background Art

[0003] The most typical problem in agricultural and horticultural pest control is the need to reduce the dosage rate of the active ingredient to reduce or avoid adverse environmental or toxicological effects while still providing effective pest control.

[0004] Another difficulty in pest control is that the repeated and exclusive use of a single insecticidal active ingredient in many cases leads to the rapid selection of pests that have developed natural or adaptive resistance to the active ingredient. Due to the multigenerational and adaptive nature of the pests, the resistance of the pests is formed in a relatively short period of time. Therefore, there is also a need for pest control agents that are effective against both the pests and their larvae and eggs.

[0005] Solving at least one of the problems such as improving biological properties, providing synergistic properties, reducing dosage rates, expanding the spectrum of activity, combining knockdown activity with long-lasting action, and resistance management to delay resistance is a long-standing need for controlling agricultural or forestry pests.

[0006] Compound I is known from WO2006013896 and belongs to the group of quinoline derivatives.

[0007]

[0008] Compound I Summary of the invention

[0009] The present invention aims to provide an insecticidal composition in view of the above-mentioned shortcomings. The insecticidal composition contains active ingredients Compound I and Compound II. The combination of Compound I and Compound II can effectively prevent or control animal pests and their larvae and eggs. We found that the combined or separate application of Compound I and Compound II or the sequential application of Compound I and Compound II can achieve a higher control effect on pests than the control rate that can be obtained by applying a single compound. The combination of Compound I and Compound II shows high efficiency, reduces the dosage rate, and reduces the load on the environment.

[0010] The insecticide composition of the present invention is realized by adopting the following technical scheme:

[0011] An insecticide composition comprising active ingredients Compound I and Compound II,

[0012]

[0013] Compound I

[0014] Compound II is one selected from the following compounds: spinosad, spinetoram, bromofenac, thiophanate, sulfoxaflor, emamectin benzoate, chlorfenapyr, ethotripsy, and bifenthrin.

[0015] The weight ratio of compound I to compound II is usually in the range of 500:1-1:500, more preferably 200:1-1:200, preferably 100:1-1:100, more preferably 50:1-1:50, more preferably 25:1-1:25, to obtain a synergistic effect; compound II is selected from one of the following compounds: spinosad, spinetoram, bromofenac, sulfanilamide, sulfoxaflor, emamectin benzoate, chlorfenapyr, ethomethrin, and bifenthrin.

[0016] The compound I and compound II described in the present invention have completely different mechanisms and modes of action. When combined, they have the effects of contact killing, stomach poisoning, egg killing, and reducing egg laying rate and hatching rate, thereby making it easier to kill pests and delaying the development of resistance.

[0017] The present invention provides an insecticidal composition, which contains active ingredients Compound I and Compound II, wherein the weight of Compound I and Compound II together accounts for 1%-90% by weight of the insecticidal composition, preferably 5%-80%, more preferably 5%-70%, further preferably 5%-60%, more preferably 5%-50%, more preferably 10%-50%, more preferably 10%-40%.

[0018] A pesticidal composition comprising active ingredients Compound I and Compound II, wherein the weight of Compound I and Compound II in total accounts for 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, or 90% of the pesticidal composition by weight.

[0019] A pesticidal composition comprises active ingredients Compound I and Compound II, and further comprises a surfactant and / or a filler.

[0020] The insecticide composition of the present invention has the following dosage forms: emulsifiable concentrate, water suspension, oil suspension, seed treatment dry powder, seed treatment suspension, water dispersible granules, wettable powder, suspoemulsion, water emulsion, microcapsule suspension, dry suspension, ultra-low volume liquid, microgranules and microemulsion.

[0021] The insecticidal composition of the present invention can be applied undiluted or diluted with water.

[0022] The insecticidal composition of the present invention unexpectedly exhibits extremely high activity in preventing or controlling pests and their larvae and eggs in treating plants, plant propagation materials, and soil in which plants grow.

[0023] The insecticidal composition of the present invention has excellent controlling efficacy on pests and their larvae and eggs at a low dosage.

[0024] In another aspect, the present invention also provides a use of an insecticidal composition for preventing or controlling pests and their larvae and eggs.

[0025] In particular, the present invention provides an insecticidal composition for preventing or controlling pests of the orders Lepidoptera, Hemiptera, Diptera, Thysanoptera, and Acarina.

[0026] The invention provides an insecticidal composition for preventing or controlling pests of the families Plutella xylostella, Tortricidae, Noctuidae, Delphacidae, Aleyrodidae, Tetranychus, Thripidae, Aphididae, Cyprinocoideae, and larvae and eggs thereof.

[0027] More particularly, the present invention provides a use of an insecticidal composition for preventing or controlling Plutella xylostella, Leaf Moth, Tetranychus cinnabarinus, Bemisia tabaci, Thrips tabaci, Bemisia tobacco aphid pests and their larvae and eggs.

[0028] The insecticide composition of the present invention is used for treating seeds to prevent the seeds from being attacked by pests.

[0029] The insecticide composition of the present invention can be applied to seeds, plants or fruits of plants or soil where plants grow or soil suitable for plant growth.

[0030] In another aspect, the present invention also provides a method for preventing or controlling pests and their larvae and eggs, wherein the pesticidal composition of the present invention is applied to target useful plants, target pests or their environment, or propagation materials of target useful plants. The plant propagation materials are seedlings, rhizomes, nursery seedlings, cuttings or seeds.

[0031] A method for preventing or controlling pests and their larvae and eggs, comprising applying the pesticidal composition of the present invention to seeds, target useful plants or soil where plants grow or soil suitable for plant growth.

[0032] A method for preventing or controlling pests and their larvae and eggs, comprising applying the pesticidal composition of the present invention to the soil before, after or before or after seed germination and / or directly applying it to the soil in contact with plant roots or soil suitable for plant growth.

[0033] A method for protecting seeds comprises contacting the seeds with an insecticidal effective amount of the insecticidal composition of the present invention before sowing and / or after germination.

[0034] The plants include: stems and leaves of plants, flowers of plants, fruits of plants, etc.

[0035] The seeds are selected from soybean, wheat, barley, rye, sorghum, peanut, sunflower, sugarcane, tobacco, rice, rapeseed, pakchoi, cabbage, beet, tomato, cowpea, carrot, cotton and corn seeds.

[0036] A method for preventing or controlling pests, comprising applying compound I and compound II separately, sequentially or simultaneously.

[0037] The pesticidal composition of the present invention can be applied in any desired manner, such as seed coating, soil drench and / or direct furrow application and / or foliar spraying, and can be applied before germination, after germination or before and after germination.

[0038] The present invention discloses an insecticide composition comprising active ingredients Compound I and Compound II, which solves at least one problem such as improving biological properties, providing synergistic properties, reducing dosage rates, expanding activity spectrum, combining knockdown activity and long-lasting effect, and managing resistance to delay resistance. DETAILED DESCRIPTION

[0039] For the convenience of understanding the present invention, the present invention lists the following embodiments. It should be understood by those skilled in the art that the embodiments are only to help understand the present invention and should not be regarded as specific limitations of the present invention.

[0040] The present invention has found that the combination of compound I and compound II can effectively prevent or control pests and their larvae and eggs. Surprisingly, the activity of the pesticidal composition of the present invention in controlling harmful organisms is much higher than the sum of the performance of the individual active compounds. This unexpected effect is a true synergistic effect, not just the addition of activity.

[0041] As used herein, the term "synergistic effect" means that the insecticidal effect of the active compound combination or composition of the present invention is greater than the sum of the effects of the individual active compounds, or in other words, the effect is superadditive.

[0042] The present invention provides an insecticide composition, which contains active ingredients Compound I and Compound II, wherein Compound II is one selected from the following compounds: spinosad, spinetoram, bromofenac, thiophanate, sulfoxaflor, emamectin benzoate, cypermethrin, ethomethrin, and bifenthrin.

[0043] The present invention provides an insecticide composition, which contains active ingredients of compound I and compound II, wherein the compound II is selected from spinosad or ethyl spinetoram.

[0044] The invention provides an insecticide composition, which contains active ingredients Compound I and Compound II, wherein Compound II is selected from bromofenac or thiofenac.

[0045] The present invention provides an insecticide composition, which contains active ingredients, compound I and compound II, wherein the compound II is selected from sulfoxaflor.

[0046] The invention provides an insecticide composition, which contains active ingredients of compound I and compound II, wherein the compound II is selected from emamectin benzoate.

[0047] The invention provides an insecticidal composition, which contains active ingredients, compound I and compound II, wherein the compound II is selected from chlorfenapyr.

[0048] The invention provides an insecticide composition, which contains active ingredients Compound I and Compound II, wherein the Compound II is selected from ethomethrin or bifenthrin.

[0049] The insecticidal composition of the present invention can be combined in the following ways:

[0050] (1) Compound I + bactericidal agent;

[0051] (2) Compound I + ethyl spinosad;

[0052] (3) Compound I + bromofenac;

[0053] (4) Compound I + thiobencarb;

[0054] (5) Compound I + chloranil;

[0055] (6) Compound I + sulfoxaflor;

[0056] (7) Compound I + emamectin benzoate;

[0057] (8) Compound I + ethoxyfenpropathrin;

[0058] (9) Compound I + bifenthrin;

[0059] The weight ratio of compound I to compound II is usually in the range of 500:1-1:500, more preferably 200:1-1:200, preferably 100:1-1:100, more preferably 50:1-1:50, more preferably 25:1-1:25, to obtain a synergistic effect.

[0060] The weight ratio of compound I to compound II of the present invention can also be, for example, 500:1, 250:1, 200:1, 150:1, 100:1, 50:1, 45:1, 40:1, 35:1, 30:1, 25:1, 20:1, 19:1, 18:1, 17:1, 16:1, 15:1, 14:1, 13:1, 12:1, 11:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:25, 1:30, 1:35, 1:40, 1:45, 1:50, 1:100, 1:150, 1:200, 1:250, 1:500.

[0061] Particularly preferred is an insecticidal composition comprising Compound I and spinosad or spinetoram; in the composition, Compound I and spinosad or spinetoram are present in a synergistically effective amount; preferably, the weight ratio of Compound I to spinosad or spinetoram is 50:1-1:50, preferably 25:1-1:25, preferably 20:1-1:20, preferably 5:1-1:20, and further preferably 1:1-1:20.

[0062] Also preferred is an insecticidal composition comprising compound I and brofenac or thiobencarb; in the composition, compound I and brofenac or thiobencarb are present in a synergistically effective amount; preferably, the weight ratio of compound I to brofenac or thiobencarb is 50:1-1:50, preferably 25:1-1:25, preferably 20:1-1:20, preferably 10:1-1:10, and further preferably 5:1-1:5.

[0063] Also particularly preferred is an insecticidal composition comprising compound I and chlorfenapyr; in the composition, compound I and chlorfenapyr are present in a synergistically effective amount; preferably, the weight ratio of compound I to chlorfenapyr is 50:1-1:50, preferably 25:1-1:50, preferably 20:1-1:50, preferably 10:1-1:50, and further preferably 5:1-1:25.

[0064] Also particularly preferred is an insecticidal composition comprising compound I and sulfoxaflor; in the composition, compound I and sulfoxaflor are present in a synergistically effective amount; preferably, the weight ratio of compound I to sulfoxaflor is 50:1-1:50, preferably 25:1-1:25, preferably 20:1-1:20, preferably 10:1-1:10, and further preferably 5:1-1:5.

[0065] Also particularly preferred is an insecticidal composition comprising compound I and emamectin benzoate; in the composition, compound I and emamectin benzoate are present in a synergistically effective amount; preferably, the weight ratio of compound I to emamectin benzoate is 500:1-1:200, preferably 250:1-1:100, preferably 250:1-1:50, preferably 200:1-1:50.

[0066] Also particularly preferred is an insecticidal composition comprising compound I and ethofumesin or bifenthrin; in the composition, compound I and ethofumesin or bifenthrin are present in a synergistically effective amount; preferably, the weight ratio of compound I to ethofumesin or bifenthrin is 50:1-1:50, preferably 25:1-1:25, preferably 20:1-1:20, preferably 10:1-1:10, and further preferably 5:1-1:5.

[0067] The preparation of compound II and its action against pests are known and can be found in The Pesticide Manual, 16th edition and other publications.

[0068] The insecticidal composition of the present invention has good plant compatibility and favorable homeothermic animal toxicity, and is suitable for controlling harmful organisms encountered in agriculture, forestry, protection of stored products and materials, and health fields, especially Insecta, Arachnida, Nematoda. They are active against usually sensitive and resistant species, and are active against all or individual developmental stages, and also achieve a surprising "synergistic" effect in preventing or controlling harmful organisms.

[0069] The present invention also provides a use of the pesticidal composition of the present invention for preventing or controlling harmful organisms. The term "harmful organism" used herein means any organism that can cause damage to the normal state of a plant, including harmful insects, arachnids, and nematodes.

[0070] The class Insecta includes the orders Lepidoptera, Coleoptera, Diptera, Hemiptera, Homoptera, Hymenoptera, Thysanoptera, Isopoda, Diplopoda, Chilopoda, Synplasia, Thysanura, Collembola, Collembola, Orthoptera, Blattodea, Dermoptera, Isoptera, and Phycoptera.

[0071] Lepidoptera pests: Pyralidae, such as Chilo suppressalis (walker), Tryporyza incertulas (walker), Cnaphalocrocism medinalis Guenee, Hellullaundalis, Conogethes punctiferlis; Pieridae, such as Pieris rapae rapae), papilioxuthus, pierisrapaecrucivora, parnaraguttata; Arctiidae such as the gypsy moth (hyphantriacunea); Noctuidae such as the cabbage looper (trichoplusiani), cabbage looper (mamestrabrassicae), beet armyworm (spodopteraexigua), cutworm (spodopteralitura), cotton bollworm (helicoverpaarmigera), oriental armyworm (Pseudaletia separate), cutworm (Agrotis ipsilon); Tortricidae such as Adoxophyesoranafasciata, Archipsfuscocureanus, Homonamagnanima; Plutellidae such as Plutellaxylotella; Gelechiidae such as Pectinophoragossypiella, Pink bollworm;

[0072] Pests of the order Hemiptera, for example, of the families Aphididae, Adelgidae or Phylloxeridae, for example Myzus persicae, Aphis gossypii, Aphis fabae, Aphis maidis (corn leaf aphid), Acyrthosiphon pisum, Aulacorthum solani, Aphis craccivora, Macrosiphum euphorbiae, Macrosiphum avenae, Metopolophium dirhodum, Rhopalosiphum padi, Schizaphis graminum, Brevicoryne brassicae, Lipaphis erysimi, Aphis serrata, citricola, Rosy apple aphid, Eriosoma lanigerum, Toxoptera aurantii and Toxoptera citricidus; Cicadellidae, such as Nephotettix cincticeps; Delphacidae, such as Laodelphax striatellus, Nilaparvata lugens and Sogatella furcifera; Pentatomidae, such as Eysarcoris ventralis and Nezara viridula; Aleyrodidae, such as Bemisia tabaci tabaci and greenhouse whitefly (Trialeurodes vaporariorum); Diaspididae, Margarodidae, Ortheziidae, Aclerdiae, Dactylopiidae, Kerridae, Pseudocoddidae; Coccidae; Eriococcidae; Asterolecaniidae, Lecanodiaspididae;or Cerococcidae, such as Pseudococcus comstocki and Planococcus citri Risso; Psyllidae, such as Psylla psylla (psyllapyrisuga), Diaphorina tabaci;

[0073] Coleoptera pests, such as: rice weevil (sitophilus oryzaeline), citrus leaf miner (PodagricomelanigricollisChe), corn weevil (S.zeamails), grain weevil (S.granarius), cabbage leaf beetle (Cabbageleafbeetle), small monkey leaf beetle (Daikon leaf beele), flea beetle (fleabeetle), grape flea beetle (Alticachalybea), curved flea beetle (phyllotretastriolata), cucumber flea beetle (Epitrixcucumeris), tobacco flea beetle (Ehirtipennis), eggplant flea beetle (E.fuscula), yellow melon (Aulacophoraindica (Gemlin), mustard leaf beetle (Phaedoncochleariae), rice water weevil (Lissorhoptrus oryzophilus), Callosobruchuyschienensis, yellow mealworm (Tenebrio molitor), corn rootworm (Diabrotica virgiferavirgifera), cucumber beetle (Diabrotica undecimpunctata howardi), copper beetle (Anomalacuprea), red copper beetle (Anomala rufocuprea), yellow flea beetle (Phyllotreta striolata), yellow melon beetle (Aulacophora femoralis), potato beetle (Leptinotarsa ​​decemlineata), rice mudworm (Oulema oryzae), bostrychidae and Cerambycidae;

[0074] Diptera pests, for example: rice leafminer (agromyza oryzae), barley leafminer (hydrelliagriseola), African daisy leafminer (liriomyza trifolii), pea leafminer (chromatomyia horticola), tomato leafminer (liriomyza bryoniae), gray ground fly (delia platura), onion fly (delia antiqua), Mediterranean fruit fly (ceratitis capiata wiedgman), apple fruit fly (Rhagoletis pomonella), cherry fruit fly (R. cingulata).

[0075] Pests of the order Coleoptera, for example, Lissorhoptrus oryzophilus, Callosobruchuys chienensis, Tenebrio molitor, Diabroticavirgifera virgifera, Diabrotica undecimpunctata howardi, Anomala cuprea, Anomala rufocuprea, Phyllotretastriolata, Aulacophora femoralis, Leptinotarsadecemlineata, Oulema oryzae, bostrychidae and Cerambycidae;

[0076] Pests of the order Acarina. For example, citrus spider mite (panonychuscitri), cinnabar spider mite (Tetranychuscinnabarinus), apple spider mite (panonychusulmi), two-spotted spider mite (tetranychusurticae), hawthorn spider mite (tetranychusviennensis), needle leaf mite (oligonychusununguis), citrus spider mite (eotetranychuskankitus), purple short whisker mite (brevipalpussphoenicis), alfalfa moss mite (bryobi apraetiosa), wheat leaf mites (Aceriatulipae), grape gall mites (Colacarusvitis), tea leaf mites (Calacaruscarinatus), tea yellow mites (Polyphagotarsonemuslatus), long-haired root mites (Rhizoglyphusrostochiensis), rough-legged flour mites (Acarussiro), citrus gall mites (Aceriasheldoni), Schlechtendali needle mites (Aculusschlechtendali), spider mites (Tetranychus spp.), Panonychus spp., wrinkled leaf mites (Phyllocoptrutaspp.), short-bearded mites (Brevipalpus spp.), etc.

[0077] Thysanopteran pests, such as Thrips palmi, Frankliniella occidentalis, Thrips alliorum (Priesner), Thrips hawaiiensis (Morgan), Scirtothripsdorsalis Hood, Frankliniella intonsa (Trybom), etc.;

[0078] Orthopteran pests for example, Acrididae; megacopta punctatissimum, eurydemarugosum, eysarcoris lewisi, eysarcoris parvus, nezara viridula, plautia stali, halymorphamista, cletus punctiger, leptocorisa chinensis, stephantis pyrioides, trigonotylus coelestialium.

[0079] Pests of the order Hymenoptera, such as the yellow-winged sawfly (Athalia rosaeruficornis), the rose sawfly (Argepagana), the black mountain ant (Formica japonica), the chestnut gall wasp (Dryocsmuskuriphilus), etc.

[0080] From the order of the Isopoda, for example, Oniscus assellus, Armadilliudium vulgare, Porcellio scaber.

[0081] Pests of the order Diplopoda, for example, Blaniulusguttulatus.

[0082] Pests of the order Chilopoda, for example, GeophiluscarpophagusScutigera spp.

[0083] Pests of the order Synthetic, for example, white pine borer (Scutigerella immaculata).

[0084] Pests of the order Thysanura, for example, Silverfish ( Lepismasaccharina ).

[0085] Pests of the order Collembola, for example, Onychiurus sarmatus.

[0086] Pests of the order Orthoptera, for example, house cricket (Acheta domesticus), Gryllotalpa spp., Asian migratory locust (Locustamigratoriamigratorioides), black locust species (Melanopluss pp.), desert locust (Schistocerca gregaria).

[0087] Pests of the order Blattaria, for example, Blatta orientalis, Periplaneta americana, Leucophae amaderae, Blattella germanica.

[0088] Pests of the order Dermoptera, for example, Forficula auricularia.

[0089] Pests of the order Isoptera, for example, Reticulitermes spp.

[0090] From the order of the Anoplura, Phthiraptera, for example, Damalinia spp., Haematopinus spp., Linognathus spp., Pediculus spp., Trichodectes spp.

[0091] Representative organisms of the class Nematoda are selected from the genera Meloidogyne spp., Heterodera spp., Globodera spp., Radopholus spp., Pratylenchus spp., Longidorus spp., etc. Preferred nematodes are Heterodera, golbodera spp., meloidogyne incognita, etc.

[0092] The insecticidal composition of the present invention is preferably particularly effective against pests of the orders Lepidoptera, Hemiptera, Diptera, Thysanoptera, and Acarina.

[0093] In particular, the insecticidal composition of the present invention is particularly effective against the following pests; specifically including the following pests:

[0094] Noctuidae, such as the cabbage looper (trichoplusiani), cabbage armyworm (mamestrabrassicae), beet armyworm (spodopteraexigua), cutworm (spodopteralitura), cotton bollworm (helicoverpaarmigera), oriental armyworm (Pseudaletia separate), and cutworm (Agrotisipsilon);

[0095] Tortricidae, such as adoxophyesoranafasciata, archipsfuscocureanus, and homonamagnanima;

[0096] Plutellidae, such as the diamondback moth (Plutellax ylotella);

[0097] Aleurodes family such as cabbage whitefly (Aleurodes brassicae), tobacco whitefly (Bemisia tabaci), greenhouse whitefly (Trialeurodes vaporariorum);

[0098] Delphacidae, such as Laodelphax striatellus, Nilaparvata lugens and Sogatella furcifera;

[0099] Tetranychidae, such as Tetranychus cinnabarinus, Tetranychus surticae, Tetranychus viennensis, Oligonychus ununguis, Eotetranychus kankitus;

[0100] Panonychus spp., such as panonychus citri and panonychusulmi;

[0101] Thripidae, such as Thrips palmi, Frankliniella occidentalis, Thrips alliorum (Priesner), Thrips shawaiiensis (Morgan), Scirtothrips dorsalis Hood, Frankliniella intonsa (Trybom), etc.

[0102] Aphididae, such as tobacco aphid (Myzus persicae), cotton aphid (Aphis gossypii), cabbage aphid (Brevicorynebrassicae), and cereal aphid (Rhopalosiphum padi);

[0103] Cerococcidae, for example, Pseudococcus comstocki and Planococcus citri Risso.

[0104] In particular, the insecticidal composition of the present invention shows a surprising "synergistic" effect on preventing or controlling pests of the families of Plutella xylostella, Tortricidae, Noctuidae, Delphacidae, Whitefly, Tetranychus, Thripidae, Aphididae, Cyclocopidae and their larvae and eggs.

[0105] The insecticidal composition of the present invention unexpectedly exhibits extremely high activity in preventing or controlling pests of the families Plutella xylostella, Tortricidae, Noctuidae, Delphacidae, Aleyrodidae, Tetranychus, Thripidae, Aphididae, Cyprinocoideae and their larvae and eggs in treating plants, plant propagation materials and soil in which plants grow.

[0106] The insecticidal composition of the present invention has excellent control efficacy on the pests of the family Plutellae, the family Tortricidae, the family Noctuidae, the family Delphacidae, the family Aleyrodidae, the family Tetranychus, the family Thripidae, the family Aphididae, the family Cyclocopsidae and the larvae and eggs thereof at a low dosage.

[0107] On the other hand, the present invention also provides a pesticidal composition for preventing or controlling pests of the families Plutella xylostella, Tortricidae, Noctuidae, Delphacidae, Aleyrodidae, Tetranychus, Thripidae, Aphididae, and Cyclocopsidae, and their larvae and eggs.

[0108] The invention provides an insecticide composition for preventing or controlling pests such as diamondback moth, leaf moth, spider mite, whitefly, tobacco thrips, tobacco aphid and the like and their larvae and eggs.

[0109] The pesticidal composition of the present invention can be applied to any and all developmental stages of pests, such as eggs, larvae, pupae and adults. Pests can be controlled by contacting the target pests, their food supply, habitat, breeding ground or their location with an insecticidally effective amount of the pesticidal composition of the present invention.

[0110] “Location” means plants, plant propagation material, soil, area, material or environment in which a pest is growing or may grow.

[0111] "Insecticidal effective amount" refers to the amount of the insecticidal composition of the present invention required to obtain an observable effect on growth, including a mortality, prevention or removal effect, a destruction effect or an effect of reducing the appearance and activity of animal pests. The insecticidal effective amount of the various insecticidal compositions used in the present invention can vary. The insecticidally effective amount of the composition will also vary depending on the prevailing conditions such as the desired insecticidal effect and duration, weather, target species, location, mode of application, etc.

[0112] According to the present invention, all plants and parts of plants can be processed. "Plant" should be understood as representing all plants and plant populations such as desired and undesirable wild plants or crops (comprising naturally grown crops) at this. Crop can be the plant obtained by conventional breeding and optimization method, or the plant obtained by biotechnology and genetic engineering method or the combination of these methods, including transgenic plants and including plant cultivars that can or cannot be protected by plant breeder's certificate. Plant parts should be understood as representing all above-ground and underground parts and plant organs such as seedlings, leaves, flowers and roots, and the example that can be mentioned is leaf, needle, stem, dry, flower, fruit body, fruit and seed and root, tuber and rhizome. The part of plant also includes plant and asexual propagation and sexual propagation material after harvest, for example seedling, tuber, rhizome, cutting and seed.

[0113] As already mentioned above, all plants and their parts can be treated according to the invention. Particular preference is given to treating according to the invention plants of plant cultivars which are in each case commercially available or in use.

[0114] The insecticidal composition of the present invention shows particularly advantageous effects when used on, for example, the following plants:

[0115] Crops: corn, rice, wheat, barley, rye, oats, sorghum, cotton, soybeans, peanuts, buckwheat, sugar beets, pakchoi, cabbage, rapeseed, sunflower, sugarcane, tobacco, etc.

[0116] Vegetables: Solanaceae vegetables (eggplant, tomato, green pepper, hot pepper, potato, etc.), Cucurbitaceae vegetables (cucumber, pumpkin, summer squash, watermelon, melon, etc.), Brassica vegetables (rapeseed, radish, turnip, horseradish, kohlrabi, cabbage, mustard, broccoli, cauliflower, etc.), Asteraceae vegetables (burdock, wormwood, artichoke, lettuce, etc.), Liliaceae vegetables (scallion, onion, garlic, asparagus, etc.), Apiaceae vegetables (carrot, parsley, celery, parsnip, etc.), Chenopodiaceae vegetables (spinach, chard, etc.), Labiate vegetables (perilla, mint, basil, etc.), strawberry, sweet potato, yam, taro, etc.

[0117] Fruit trees: pome fruits (apple, pear, Japanese pear, papaya), stone fruits (peach, plum, nectarine, plum, yellow peach, apricot, prune, etc.), citrus fruits (Wenzhou mandarin orange, tangerine, lemon, lime, grapefruit, etc.), nuts (chestnut, walnut, hazelnut, almond, cashew, etc.), berries (cranberry, blackberry), grapes, persimmon, olive, loquat, banana, coffee, date, coconut, oil coconut.

[0118] Trees other than fruit trees: tea, mulberry, flowering trees (azalea, camellia, hydrangea, oil-tea tree, Japanese fennel, cherry, crape myrtle, golden osmanthus, etc.), street trees (birch, ginkgo, lilac, maple, oak, poplar, bauhinia, liquidambar, sycamore, beech, Japanese cedar, fir, Japanese hemlock, juniper, pine, spruce, yew, elm, etc.), coral tree, podocarpus, cedar, Japanese cypress, croton, photinia, etc.

[0119] Lawn: Zoysia grass (Zoysia japonica, Zoysia ditchleaf, etc.), Bermuda grass (Bermuda grass, etc.), Bentgrass (Giant bentgrass, creeping bentgrass, dryland bentgrass, etc.), Bluegrass (Bluegrass, Birdgrass, etc.), Fescue (Tall fescue, red fescue, creeping red fescue, etc.), Ryegrass (Barramundi, Lolium, etc.), Wild grass, Timothy, etc.

[0120] Others: flowers (rose, dianthus, chrysanthemum, platycodon, dianthus, gerbera, marigold, sage, petunia, verbena, tulip, gentian, lily, pansy, cyclamen, orchid, convalescentia, lavender, violet, kale, primrose, euphorbia, daisy, orchid, begonia, etc.), biofuel plants (jatropha, safflower, camelina, switchgrass, miscanthus, reed, arundo donax, kenaf, cassava, willow, etc.), ornamental plants, etc.

[0121] The insecticide composition of the present invention has good plant compatibility and is suitable for controlling pests, especially Insecta, Arachnida, Nematoda, as well as fungi, rodents, microorganisms, etc.; especially Plutella xylostella, Folliculidae, Noctuidae, Delphacidae, Aleyrodidae, Tetranychus, Thripidae, Aphididae, Cynocopsidae pests and their larvae and eggs. It is preferably suitable for foliar treatment, soil treatment and seed treatment.

[0122] On the other hand, the present invention also provides a method for preventing or controlling pests and their larvae and eggs, wherein the pesticidal composition of the present invention is applied to target useful plants, target pests or their environment, or propagation materials of target useful plants. The method can be performed before or after the plants, plant propagation materials or environment are infested by pests.

[0123] The term "plant propagation material" should be construed as referring to all plant parts with reproductive capacity, for example seed, which can be used to breed the latter, and vegetable materials such as cuttings or tubers (for example potato). Therefore, plant parts used herein include plant propagation materials. For example, seed, root, fruit, tuber, bulb, rhizome and plant parts can be mentioned. Sprouting plants and effective plants that are suppressed after germination or emergence from soil. Young plants can be protected by all or local treatments before transplanting by dipping.

[0124] The plant propagation material is seedlings, rhizomes, nursery seedlings, cuttings or seeds. Seeds are preferred.

[0125] The insecticide composition of the present invention can be applied to seeds, plants or fruits of plants or soil where plants grow or soil suitable for plant growth.

[0126] A method for protecting seeds comprises contacting the seeds with an insecticidal effective amount of the insecticidal composition of the present invention before sowing and / or after germination.

[0127] The plants include: stems and leaves of plants, flowers of plants, fruits of plants, etc.

[0128] The seeds are selected from soybean, wheat, barley, rye, sorghum, peanut, sunflower, sugarcane, tobacco, rice, rapeseed, pakchoi, cabbage, beet, tomato, cowpea, carrot, cotton and corn seeds.

[0129] Thus, the present invention provides a method for protecting seeds, seedling roots and shoots from soil and foliar insect infestation, comprising contacting the seeds with an effective amount of the insecticidal composition of the present invention before sowing and / or after germination.

[0130] The present invention also provides a method for controlling or preventing pests and their larvae and eggs in plant propagation materials and in plant organs, plant parts and / or plants grown thereafter, comprising applying the pesticidal composition of the present invention to the plant propagation materials or their environment. The plant propagation materials are preferably seeds.

[0131] Most of the damage to crop plants caused by pests occurs as early as when the seed is infested, during storage and after the seed is sown in the soil and during or after germination of the plant. This phase is particularly critical, since the roots and shoots of the growing plant are particularly sensitive and even minor damage can lead to the death of the entire plant. Therefore, it is of particular interest to protect the seed and the germinating plant by using suitable compositions.

[0132] The present invention also particularly relates to a method for protecting seeds and germinating plants from pests and their larvae and eggs by treating the seeds with the pesticidal composition of the present invention. The method of protecting seeds and germinating plants from the pests of the family Plutellae, the family Tortricidae, the family Noctuidae, the family Delphacidae, the family Aleyrodidae, the family Tetranychidae, the family Thripidae, the family Aphididae, the family Cyclocopsidae and their larvae and eggs comprises a method of treating the seeds with compound I and compound II at the same time. It also includes a method of treating the seeds with compound I and compound II at different times.

[0133] A method for preventing or controlling pests and their larvae and eggs, comprising treating seeds for expected plant growth with a synergistically effective amount of the pesticidal composition of the present invention before sowing and / or after germination.

[0134] The invention also relates to the use of the insecticidal composition according to the invention for treating seeds to protect the seeds and the plants grown therefrom from attack by pests and their larvae and eggs.

[0135] Furthermore, the present invention also relates to seeds treated with the pesticidal composition of the present invention to thereby obtain protection from pests and their larvae and eggs.

[0136] The present invention also relates to seeds treated with compound I and compound II at the same time. The present invention also relates to seeds treated with compound I and compound II at different times. For seeds treated with compound I and compound II at different times, the active compounds of the pesticidal composition of the present invention may be present in different layers on the seeds. Among them, the layers containing compound I and compound II may be optionally separated by an intermediate layer. The present invention also relates to seeds in which compound I and compound II are applied as coating components or as one or more additional layers outside the coating.

[0137] Insecticidal composition of the present invention can be applied to the seed of any physiological state.Preferably seed is in a sufficiently durable state, thereby is not damaged during the treatment process.Generally, seed can be harvested from the field, removed from the plant, separated from the seed of any cob, stem, husk and surrounding pulp or other non-seed plant material.Seed can also preferably be biologically stable, to reach the degree that treatment does not cause biological damage to seed.Can be applied to seed at any time between seed harvesting and seed sowing or during the sowing process.Seed can also be germinated before or after treatment.

[0138] The seeds treated with the pesticidal composition of the present invention can be stored, managed, sown and cultivated.

[0139] Seed treatment occurs on unsown seeds, the term "unsown seeds" being intended to include seeds at any stage between seed harvest and seed sowing in the ground for plant germination and growth purposes. Preferably, treatment occurs before seed sowing, so that the sown seeds have been pretreated with the combination. In particular, seed coating or seed pelleting is preferred in the treatment of the inventive combination. After treatment, the ingredients in each combination adhere to the seeds and can therefore be used for pest control.

[0140] Seed treatment methods include all methods known to the person skilled in the art that are suitable for treating seeds, such as seed dressing, seed coating, seed soaking, seed coating, seed multilayer coating, seed shelling, seed soaking, seed dusting and seed pelleting.

[0141] The composition of the present invention can be applied to seeds, plants or fruits of plants or soil where plants grow or soil suitable for plant growth.

[0142] The present invention also provides a method for preventing or controlling pests and their larvae and eggs, comprising applying the pesticidal composition of the present invention to seeds, target useful plants or soil where plants grow or soil suitable for plant growth.

[0143] On the other hand, the present invention also provides a method for preventing or controlling pests and their larvae and eggs, wherein the insecticidal composition of the present invention is applied to the soil before, after or before or after seed germination and / or directly applied to the soil in contact with plant roots or soil suitable for plant growth.

[0144] The present invention also provides a method for protecting plants from pests and their larvae and eggs, comprising applying the pesticidal composition of the present invention to an environment, habitat or storage area where useful plants grow. The environment and habitat where plants grow refer to a support that enables crops to take root and grow, such as soil, water, etc. Specific raw materials can be sand, pumice, vermiculite, diatomaceous earth, agar, gelatinous substances, polymer substances, asbestos, sawdust, bark, etc. Soil is preferred.

[0145] The present invention also provides a method for protecting plants from attack by pests of the family Plutellae, Puccinellidae, Noctuidae, Delphacidae, Aleyrodidae, Tetranychus, Thripidae, Aphididae, Cyprinocoideae and their larvae and eggs, comprising applying active ingredients Compound I and Compound II jointly, separately or sequentially. In the case of separate application, the order generally has no effect on the results of the control measures.

[0146] A method for preventing or controlling pests and their larvae and eggs, comprising applying compound I and compound II separately, sequentially or simultaneously.

[0147] The invention also provides a method for protecting useful plants from attack by pests and their larvae and eggs, which comprises applying a combination comprising compound I and compound II to the target useful plants or their environment, to the target pests or their environment, to propagation material of the target useful plants in any desired order or simultaneously.

[0148] The insecticidal compositions according to the invention include both ready-to-use compositions which can be applied to plants or plant propagation materials using suitable devices and commercially available concentrates which have to be diluted with water before application.

[0149] The insecticidal composition of the present invention can be applied undiluted or diluted with water.

[0150] The present invention provides a method for preventing or controlling pests and their larvae and eggs, wherein the pesticidal composition of the present invention is applied to a target useful plant or its environment, or a propagation material of the target useful plant, and other pesticides can be applied before, simultaneously with, or independently of the application of compound I and compound II, and when compound I and compound II are applied separately, each other pesticide can be applied before, simultaneously with, between, or independently of the application of compound I and compound II, and independently of the application of compound I and compound II.

[0151] It is common and advantageous to apply the pesticidal composition of the present invention at the following dosages:

[0152] For foliar treatment: 0.1-10000 g / ha, preferably 10-1000 g / ha, more preferably 10-500 g / ha, even more preferably 10-300 g / ha;

[0153] For seed treatment: 1-1000 g / 100 kg seeds, preferably 100-1000 g / 100 kg seeds;

[0154] For soil treatment: 1-10000 g / ha, preferably 10-1000 g / ha.

[0155] The above dosages are only general exemplary dosages. During actual application, those skilled in the art will adjust the application rate according to actual conditions and needs, especially according to the properties of the plants or crops to be treated and the pest situation.

[0156] Methods for treating target pests, target useful plants, or seeds, soil with the pesticidal composition of the present invention include, for example, spreading treatment, soil treatment, surface treatment and fumigation treatment. Spreading treatment includes, for example, spreading, spraying, atomizing, and granule application. Soil treatment includes, for example, soil irrigation and soil mixing. Surface treatment includes, for example, coating and covering. Fumigation treatment includes, for example, covering the soil with a polyethylene film after injection into the soil.

[0157] Applicators usually use the insecticidal composition of the present invention in a small backpack sprayer, spray tank, spray plane or irrigation system. The insecticidal composition of the present invention is usually formulated with water, buffer and / or other adjuvants to the desired application concentration to obtain a ready-to-use spray solution.

[0158] The total amount of active ingredients in the insecticide composition of the present invention can be selected according to specific factors to achieve the desired effect, such as the dosage form, the object to be applied, the application method, etc.

[0159] The present invention provides an insecticidal composition, which contains active ingredients Compound I and Compound II, wherein the weight of Compound I and Compound II together accounts for 1%-90% by weight of the insecticidal composition, preferably 5%-80%, more preferably 5%-70%, further preferably 5%-60%, more preferably 5%-50%, more preferably 10%-50%, more preferably 10%-40%.

[0160] A pesticidal composition comprising active ingredients Compound I and Compound II, wherein the weight of Compound I and Compound II in total accounts for 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, or 90% of the pesticidal composition by weight.

[0161] The insecticide composition of the present invention may optionally contain auxiliary ingredients such as agronomically acceptable surfactants and / or fillers. Preferably, the auxiliary ingredient is one or a mixture of a dispersant, a wetting agent, an antifreeze agent, a thickener, a defoaming agent, a disintegrant, a binder, and an auxiliary carrier.

[0162] According to the present invention, the term "filler" refers to a natural or synthetic organic or inorganic compound that can be combined or associated with an active compound to make it easier to apply to an object (e.g., a plant, a crop, or a grass). Therefore, the filler is preferably inert and should at least be agronomically acceptable. The filler can be solid or liquid.

[0163] The inactive filler that can be used in the present invention can be either solid or liquid.

[0164] As solid fillers, there may be used, for example, talc, bentonite, clay, kaolin, diatomaceous earth, white carbon, calcium carbonate, acid clay, silica, zeolite, attapulgite, pumice, ammonium sulfate, sodium sulfate and urea.

[0165] The liquid filler may be selected from the following materials, such as water, isopropanol, butanol, tetrahydrofuran, ethylene glycol, propylene glycol, ethyl acetate, methyl oleate, dimethylformamide, dimethylacetamide, dimethyl sulfoxide and vegetable oil.

[0166] Surfactants can be used to emulsify, disperse, solubilize and / or wet the active ingredient compounds. For example, fatty alcohol polyoxyethylene ethers, polyoxyethylene alkyl aryl ethers, polyoxyethylene higher fatty acid esters, phosphate esters of polyoxyethylene alcohols or phenols, fatty acid esters of polyols, naphthalenesulfonic acid polymers, lignin sulfonates, high molecular comb-shaped branched copolymers, butylnaphthalenesulfonates, alkylarylsulfonates, alkylsulfosuccinates, oils and fats, condensates of fatty alcohols and ethylene oxide, polyacrylates of alkylnaphthalenesulfonates, protein hydrolysates, suitable oligosaccharides or polymers, for example based on vinyl monomers, acrylic acid, polyoxyethylene and / or polyoxypropylene alone or in combination with, for example, (poly)alcohols or (poly)amines.

[0167] In order to disperse, stabilize and adhere the active ingredient compounds, auxiliary agents such as xanthan gum, magnesium aluminum silicate, gelatin, starch, cellulose methyl ether, polyvinyl alcohol, polyvinyl acetate and natural phospholipids (such as cephalin and lecithin) as well as synthetic phospholipids, bentonite, sodium lignin sulfonate, etc. can be used.

[0168] Among them, ethylene glycol, propylene glycol, glycerol, and sorbitol can be selected as antifreeze agents. As deflocculants for suspended products, auxiliary agents such as naphthalenesulfonic acid polymers and polyphosphates can be used. As defoamers, silicone defoamers can be used. To improve the fluidity of solid products, auxiliary agents such as paraffin, stearate, and alkyl phosphate can be used.

[0169] Colorants that can be used include, for example, inorganic pigments such as iron oxide, titanium oxide and Prussian blue; and organic pigments / dyes such as alizarin dyes, azo dyes and metal phthalocyanine dyes; and trace elements such as iron salts, manganese salts, boron salts, copper salts, cobalt salts, molybdenum salts and zinc salts.

[0170] Optionally, other additional components may also be included, such as protective colloids, adhesives, thickeners, thixotropic agents, penetrants, stabilizers, masking agents.

[0171] The insecticidal composition of the present invention can be used by itself, or can be used in the form of its preparation or the use form prepared therefrom according to its respective physical and / or chemical properties, such as aerosol, microcapsule suspension, cold mist, hot mist, microcapsule granules, fine granules, suspension for seed treatment, ready-to-use solution, powder, emulsifiable concentrate, oil-in-water emulsion, water-in-oil emulsion, large granules, microgranules, oil-dispersible powder, oil suspension, oil, foam, paste, seed coating, suspension, suspension emulsion, aqueous solvent, suspension, wettable powder, soluble powder, dust and granules, water-soluble granules or tablets, water-soluble powder for seed treatment, wettable powder, natural products and synthetic substances impregnated with active ingredients, microcapsules in polymeric materials and seed coating materials, and ultra-low volume cold mist and hot mist preparations.

[0172] The preferred dosage forms of the insecticide composition of the present invention are emulsifiable concentrates, aqueous suspensions, oil suspensions, seed treatment dry powders, seed treatment suspensions, water dispersible granules, wettable powders, suspoemulsions, emulsions in water, microcapsule suspensions, dry suspensions, ultra-low volume liquids, microgranules, and microemulsions.

[0173] The pesticidal composition of the present invention can also be used in combination with other active ingredients, such as fungicides, bactericides, attractants, insecticides, miticides, nematicides, growth regulators, herbicides, safeners, fertilizers or chemical semioms.

[0174] The preparations of the present invention can be prepared by mixing the active ingredients with conventional additives in a known manner, such as conventional extenders and solvents or diluents, emulsifiers, dispersants, and / or binders or fixatives, wetting agents, waterproofing agents, and, if necessary, driers and colorants, stabilizers, pigments, defoamers, preservatives, thickeners, water and other processing aids.

[0175] The insecticidal compositions of the present invention include not only those that can be immediately applied to the object to be treated by means of suitable equipment such as spraying or dusting equipment, but also concentrated commercial compositions that need to be diluted before application to the object.

[0176] The insecticidal composition of the present invention may be formulated into a preparation suitable for application in the form of a combination of its active ingredient compounds, or may be applied in the form of a combination of its commercial preparations at appropriate dosages.

[0177] Formulation Examples

[0178] Example 1 Wettable powder

[0179] Compound I 5%

[0180] Spinosad 2.5%

[0181] Sodium lauryl sulfate 1%

[0182] Sodium lignin sulfate 9%

[0183] Kaolin to 100%

[0184] The above components are mixed according to proportion, ground and pulverized to prepare wettable powder.

[0185] Example 2 Aqueous Suspension

[0186] Compound I 10%

[0187] Chlorfenapyr 10%

[0188] Polystyrylphenylether sulfate 5%

[0189] 1% xanthan gum aqueous solution 1%

[0190] Bentonite 1.5%

[0191] Propylene glycol 5%

[0192] Polysiloxane defoamer 0.05%

[0193] Water replenishment to 100%

[0194] All ingredients except 1% ​​xanthan gum aqueous solution and appropriate amount of water were premixed together, and then the mixture was ground by a wet grinder. Finally, 1% xanthan gum aqueous solution and the remaining water were added to the ground product to prepare an aqueous suspension.

[0195] Example 3 Emulsifiable Concentrate

[0196] Compound I 3%

[0197] Bifenthrin 3%

[0198] Ethoxylated fatty alcohol 8%

[0199] Calcium dodecylbenzenesulfonate 5%

[0200] N,N-dimethylformamide 20%

[0201] SOLVESSO 200 Top up to 100%

[0202] The above ingredients are uniformly mixed and dissolved to obtain an emulsifiable concentrate.

[0203] Example 4 Water dispersible granules

[0204] Compound I 25%

[0205] Emamectin benzoate 5%

[0206] Modified sodium lignin sulfonate 2%

[0207] Talc 10%

[0208] Clay replenishment to 100%

[0209] The above ingredients are uniformly mixed and ground, and then a certain amount of water is added to mix and extrude the materials, and then the water-dispersible granules are obtained after drying and sieving.

[0210] Example 5 Aqueous Suspension

[0211] Compound I 10%

[0212] Ethofenprox 10%

[0213] Polyoxyethylene styryl phenyl ether 3%

[0214] Sodium alkylnaphthalene sulfonate formaldehyde condensate 3%

[0215] 1% xanthan gum aqueous solution 1%

[0216] Bentonite 0.35%

[0217] Propylene glycol 7%

[0218] Polysiloxane defoamer 0.03%

[0219] Water replenishment to 100%

[0220] All ingredients except 1% ​​xanthan gum aqueous solution and appropriate amount of water were premixed together, and then the mixture was ground by a wet grinder. Finally, 1% xanthan gum aqueous solution and the remaining water were added to the ground product to prepare an aqueous suspension.

[0221] Example 6 Aqueous Suspension

[0222] Compound I 4%

[0223] Sulfoxaflor 20%

[0224] Sodium lignin sulfate 8%

[0225] 1% xanthan gum aqueous solution 1%

[0226] Bentonite 0.35%

[0227] Propylene glycol 7%

[0228] Polysiloxane defoamer 0.05%

[0229] Water replenishment to 100%

[0230] All ingredients except 1% ​​xanthan gum aqueous solution and appropriate amount of water were premixed together, and then the mixture was ground by a wet grinder. Finally, 1% xanthan gum aqueous solution and the remaining water were added to the ground product to prepare an aqueous suspension.

[0231] The above ratios are weight percentage ratios.

[0232] Biological test cases

[0233] The expected effect of a specific combination of two active ingredients can be calculated using the so-called "Colby formula" (see SR Colby, "Calculating Synergistic and Antagonistic Responses of Herbicide Combinations", Weeds 1967, 15, 20-22):

[0234]

[0235] X is the control effect when the active ingredient compound of formula I is used at a dosage of mg / ha or a concentration of m ppm, expressed as a percentage of the untreated control,

[0236] Y is the control effect when the active ingredient compound II is used at an amount of ng / ha or a concentration of n ppm, expressed as a percentage of the untreated control,

[0237] E is the control effect when the active components of the compound of formula I and compound II are used in an amount of m and ng / ha or a concentration of m and n ppm, expressed as a percentage of the untreated control,

[0238] If the actual control effect exceeds the calculated value, the lethal effect of the combination is superadditive, that is, there is a synergistic effect.

[0239] Test Example 1 Diamondback moth test

[0240] Preparation of drug solution: Compound I and Compound II stock drugs were prepared into mother solution with acetone, and then diluted with 0.1% Tween-80 aqueous solution to the required concentration.

[0241] Select 2nd-instar Plutella xylostella larvae that have been continuously reared indoors and have a consistent physiological state. Select cabbage leaves with consistent growth to make suitable leaf discs.

[0242] Immerse the leaf disc in the solution of the test agent, take it out after 10 seconds, dry it, place it in a petri dish containing moisturizing filter paper, and inoculate the test insects. Inoculate about 10 test insects per repetition. Repeat 4 times for each treatment. Set up a treatment without the agent (containing organic solvents and emulsifiers) as a blank control.

[0243] The treated test insects were covered and placed in a o C, Reared and observed in a constant temperature incubator with a relative humidity of 60%-80% and a light cycle of L:D = (16:8)h.

[0244] After 48 hours in the incubator, check the results. The criterion for judging death is: if the insect body has no reaction or cannot react normally when the insect body is touched lightly with a needle, it is considered dead.

[0245] During the test, the preparation of the liquid medicine should be accurate to reduce errors; the operation should be skillful and fast, and the test operation specifications should be followed to ensure the accuracy of the test. If the mortality rate of the blank control test exceeds 20%, the test needs to be repeated.

[0246] Calculation method:

[0247] Mortality rate (%) = (number of live worms before medication - number of live worms after medication) / number of live worms before medication × 100

[0248] Control effect % = ((mortality rate of treatment group - mortality rate of control group) / (100 - mortality rate of control group)) × 100

[0249] Table 1 Effect of the combination of compound I and compound II on Plutella xylostella

[0250]

[0251] Test Example 2 Test on Thrips

[0252] Preparation of drug solution: Compound I and Compound II stock drugs were prepared into mother solution with acetone, and then diluted with 0.1% Tween-80 aqueous solution to the required concentration.

[0253] The tobacco thrips were used as the test pests. The collected tobacco thrips were inoculated into the eggplants planted in the greenhouse for long-term breeding. Before the experiment, the tobacco thrips were selected by microscopic examination and raised on the eggplant plants planted in the greenhouse (no other types of thrips). The breeding conditions were a glass net room, natural light, and the cycle was about 16 (L): 8 (D). The highest temperature was 28 o C, minimum 15 o C, the maximum humidity is 95%, the minimum is 65%. Select F1 generation adults for testing. Conduct indoor tests with 20-40 heads as a group. Conduct according to the insect immersion method (NY / T 1154.6-2006).

[0254] Cut off the eggplant leaves with the tested thrips adults, immerse them in the solution for 5-10 seconds, then take them out. Use filter paper to absorb the excess solution on the leaves and thrips. Use a fine soft brush to transfer the thrips to fresh non-toxic eggplant leaves, place them in a culture tank, cover them, keep them ventilated, and use a small wet cotton ball to maintain humidity. Place the culture tank containing the treated thrips at 25±1 o C, and kept and observed in a constant temperature incubator with a relative humidity of 60%-80%. Each treatment was repeated 4 times. A treatment without drugs (containing organic solvents and emulsifiers) was set as a blank control.

[0255] After 24 hours of treatment, investigate the mortality of the test insects. The criterion for judging mortality is that there is no obvious reaction or movement when a soft brush is touched. Record the total number of insects and the number of dead insects. Calculate the mortality rate and control effect.

[0256] During the test, the preparation of the liquid medicine should be accurate to reduce errors; the operation should be skillful and fast, and the test operation specifications should be followed to ensure the accuracy of the test. If the mortality rate of the blank control test exceeds 20%, the test needs to be repeated.

[0257] Calculation method:

[0258] Mortality rate (%) = number of dead test insects / number of test insects before drug administration × 100

[0259] Prevention effect % = ((mortality rate of treatment group - mortality rate of control group) / (100 - mortality rate of control group)) × 100

[0260] Table 2 Test of the combination of compound I and compound II against Thrips tabaci

[0261]

[0262] Experiment 3: Tomato whitefly experiment

[0263] Preparation of drug solution: Compound I and Compound II stock drugs were prepared into mother solution with acetone, and then diluted with 0.1% Tween-80 aqueous solution to the required concentration.

[0264] Before the test, insect-free tomato seedlings in greenhouse pots planted under insect-proof nets were inoculated with whiteflies. When the eggs were hatched and developed into 2-3 instar nymphs of the F1 generation, tomato leaves were cut and examined under a microscope to remove eggs and other non-test insect stages. 30-50 nymphs were tested on each leaf for future testing.

[0265] The whiteflies and tomato leaves were immersed in the prepared solution for 5 seconds, taken out, and the excess solution was absorbed with absorbent paper, and placed in a plastic beaker with a diameter of 6 cm and a height of 10 cm. o C, and kept in a constant temperature incubator with a relative humidity of 60%-80%. Each treatment was repeated 4 times. A treatment without drugs (containing organic solvents and emulsifiers) was set as a blank control.

[0266] 72 hours after treatment, check the death of the test insects under a microscope. The criterion for judging death is that the insect body is shriveled and the color turns yellow. If the control mortality rate is greater than 20%, repeat the test. Record the total number of insects and the number of dead insects. Calculate the mortality rate and control effect.

[0267] During the test, the preparation of the liquid medicine should be accurate to reduce errors; the operation should be skillful and fast, and the test operation specifications should be followed to ensure the accuracy of the test. If the mortality rate of the blank control test exceeds 20%, the test needs to be repeated.

[0268] Calculation method:

[0269] Mortality rate (%) = number of dead test insects / number of test insects before drug administration × 100

[0270] Prevention effect % = (mortality rate of treatment group - mortality rate of control group) / (100 - mortality rate of control group) × 100

[0271] Table 3 Test of the combination of compound I and compound II against tomato whitefly

[0272]

[0273] Test 4: Cotton spider mite test

[0274] Preparation of drug solution: Compound I and Compound II stock drugs were prepared into mother solution with acetone, and then diluted with 0.1% Tween-80 aqueous solution to the required concentration.

[0275] Vermilion spider mites were raised in the laboratory on cotton seedlings for generations, and the test insects were adult mites. Female adult mites that were raised indoors and in the same physiological state were selected for testing. Double-sided tape was cut into 2 cm long pieces and attached to one end of the slide. Then healthy female adult mites were selected and their backs were attached to the double-sided tape (be careful not to stick to the mite legs, antennae and mouthparts), 30 per piece, placed in a container padded with a wet sponge, covered with a lid, and placed at 25 ± 1 o C, the specimens were examined under a microscope after 2 h, and dead and injured individuals were removed to make up 30 heads per plate.

[0276] The spider mite glass slide immersion method (NY / T 1154.12-2008) was used. The glass slide with spider mites was immersed in the drug solution and gently shaken for 5 seconds before being taken out. The excess drug solution was absorbed with absorbent paper, and the slide was placed on a white disk with a wet sponge. The slide was covered with a light-transmitting plastic wrap and pierced with an insect needle to allow air to pass through. Each treatment was repeated 4 times. A treatment without drug (containing organic solvents and emulsifiers) was set as a blank control.

[0277] Place the white disk containing the treated spider mite at a temperature of 25 ± 1 oC, and were raised and observed in a constant temperature incubator with a relative humidity of 60%-80%.

[0278] After 48 hours of treatment, the mites were judged dead if there was no obvious reaction when the legs, antennae or whiskers were lightly touched with a soft brush under a stereoscope. The number of dead mites was recorded.

[0279] During the test, the preparation of the liquid medicine should be accurate to reduce errors; the operation should be skillful and fast, and the test operation specifications should be followed to ensure the accuracy of the test. If the mortality rate of the blank control test exceeds 20%, the test needs to be repeated.

[0280] Calculation method:

[0281] Mortality rate (%) = number of dead mites / number of test insects before drug administration × 100

[0282] Control effect % = (mortality rate of treatment group - mortality rate of control group) / (100 - mortality rate of control group) × 100

[0283] Table 4 Test of the combination of compound I and compound II against Tetranychus cinnabarinus

[0284]

[0285] The test results in Tables 1 to 4 show that the combination of Compound I and Compound II achieves an unexpected synergistic effect in controlling Plutella xylostella, Thrips, Bemisia tabaci and Tetranychus cinnabarinus.

Claims

1. An insecticide composition comprising active ingredients Compound I and Compound II, Compound I; The compound II is selected from sulfoxaflor, and the weight ratio of the compound I to the compound II is 50:1-1:

50.

2. The insecticidal composition according to claim 1, characterized in that The weight ratio of the compound I to the compound II is 25:1-1:

25.

3. The insecticidal composition according to claim 1, characterized in that The weight ratio of the compound I to the compound II is 20:1-1:

20.

4. The insecticidal composition according to claim 1, characterized in that The weight ratio of the compound I to the compound II is 10:1-1:

10.

5. The insecticidal composition according to claim 1, characterized in that The weight ratio of the compound I to the compound II is 5:1-1:

5.

6. The insecticidal composition according to claim 1, characterized in that It may also contain surfactants and / or fillers.

7. The insecticidal composition according to claim 1, characterized in that The weight of the compound I and the compound II together accounts for 1% to 90% by weight of the insecticide composition.

8. The insecticidal composition according to claim 1, characterized in that The weight of the compound I and the compound II together accounts for 5% to 80% by weight of the insecticide composition.

9. The insecticidal composition according to claim 1, characterized in that The insecticide composition has the following dosage forms: emulsifiable concentrate, water suspension, oil suspension, seed treatment dry powder, seed treatment suspension, water dispersible granules, wettable powder, suspoemulsion, water emulsion, microcapsule suspension, dry suspension, ultra-low volume liquid, microgranules and microemulsion.

10. Use of the insecticide composition according to claim 1 for preventing or controlling Bemisia tabaci and Thrips tabaci and their larvae and eggs.

11. A method for preventing or controlling pests and their larvae and eggs, characterized in that: The insecticide composition of claim 1 is applied to target useful plants, target pests or their environment, and propagation materials of target useful plants; the pests are whiteflies and Thrips tabaci.

12. A method for preventing or controlling pests and their larvae and eggs, characterized in that: The insecticide composition of claim 1 is applied to seeds, target useful plants or soil where plants grow or soil suitable for plant growth; the pests are whiteflies and tabaci thrips.

13. A method for preventing or controlling pests and their larvae and eggs, characterized in that: The insecticide composition of claim 1 is applied to the soil before, after or before or after seed germination and / or directly applied to the soil in contact with plant roots or soil suitable for plant growth; the pests are whiteflies and tobacco thrips.

14. A method for protecting seeds, characterized in that: The seeds are contacted with an insecticidal effective amount of the insecticidal composition according to claim 1 before sowing and / or after germination.

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