A high-precision quantitative pipette gun applied to biological medicine test and detection

Abstract

The application discloses a high-precision quantitative pipetting gun applied to biological medicine tests and detection, relates to the technical field of being applied to biological medicine tests and detection, and comprises an environment information acquisition module, an environment influence analysis module, a spring basic information acquisition module, a spring influence analysis module, a liquid suction information analysis and operation module, a pipetting gun image acquisition module, a pipetting effect analysis module and secondary pipetting control. Through analysis of environment influence factors of the pipetting gun, the most suitable required environment is obtained, and spring influence factors of the pipetting gun are split and screened, so that the defects in the prior art are solved, automatic and intelligent pipetting operation of the pipetting gun is realized, the accuracy of pipetting is guaranteed, the experience of users is improved, the test efficiency is improved, and the reputation of the pipetting gun is improved to a certain extent.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of biological medicine, in particular to a high-precision quantitative pipette for biological medicine test and detection. BACKGROUND

[0002] The pipette is indispensable equipment for biological medicine experiment at present, and its application is very extensive and rich. Users can obtain various convenience, and the high precision of the pipette can help users obtain more accurate liquid volume. Therefore, in order to guarantee the pipetting effect, it is necessary to control the pipetting of the pipette.

[0003] The current use of the pipette is basically based on human control, but each operation of the human cannot be completely consistent. Such behavior will cause the inaccuracy of the pipetting effect, which will bring unpredictable consequences to the experimental results, and will lead to the failure of the experiment, and will greatly waste the time and effort of the user. On the other hand, when the current pipette is used, the temperature difference between the temperature of the pipette tip and the temperature of the liquid to be pipetted is one of the factors affecting the pipetting accuracy, and the inclination of the pipette affects the pipetting effect of the pipette. In the current technology, the influence of the temperature difference between the temperature of the pipette tip and the temperature of the liquid to be pipetted on the pipette is not considered when the pipette is used, the accuracy of the pipetting cannot be guaranteed, and after the pipetting is completed, the inclination of the pipette and the volume of the liquid to be pipetted are not analyzed, so the pipetting effect of the pipette cannot be guaranteed, which further reduces the accuracy of the pipetting and reduces the user's experience to a certain extent. SUMMARY

[0004] In view of the above technical problems, the purpose of the present application is to provide a high-precision quantitative pipette for biological medicine test and detection.

[0005] In order to solve the above technical problems, the technical scheme adopted by the present application is as follows: the present application provides a high-precision quantitative pipette for biological medicine test and detection, comprising: an environmental information acquisition module: for acquiring the temperature, humidity and temperature of the liquid to be pipetted corresponding to the pipette tip in the pipette;

[0006] An environmental influence analysis module is used to analyze the environmental influence factor corresponding to the pipette according to the temperature, humidity and temperature of the liquid to be pipetted corresponding to the pipette tip in the pipette;

[0007] A spring basic information acquisition module is used to acquire the basic information corresponding to the spring in the pipette, wherein the basic information includes the number of uses and the thickness;

[0008] A spring influence analysis module is used to analyze the spring influence factor corresponding to the pipette according to the basic information corresponding to the spring in the pipette;

[0009] Pipetting information analysis and operation module: used for analyzing pipetting information of the pipette according to the environmental influence factor and the spring influence factor corresponding to the pipette, and then performing pipetting according to the pipetting information of the pipette, wherein the pipetting information includes suction force and suction speed;

[0010] Pipette image acquisition module: used for acquiring the image corresponding to the pipette when the pipetting of the pipette is completed;

[0011] Pipetting effect analysis module: used for analyzing and judging the pipetting effect according to the image corresponding to the pipette;

[0012] Secondary pipetting control: when the pipetting effect is unqualified, analyzing the secondary pipetting information corresponding to the pipette and performing secondary pipetting.

[0013] Preferably, the temperature corresponding to the pipette tip in the pipette, the humidity and the temperature corresponding to the liquid to be pipetted in the biological and pharmaceutical experiment are collected, and the collection process is as follows:

[0014] An electronic temperature sensor is placed in the biological and pharmaceutical experiment, and then the temperature information corresponding to the pipette tip and the liquid to be pipetted in the biological and pharmaceutical laboratory is collected by the electronic temperature sensor, and the set temperature is obtained;

[0015] An electronic humidity sensor is placed in the biological and pharmaceutical experiment, and then the humidity corresponding to the pipette tip in the biological and pharmaceutical laboratory is collected by the electronic temperature and humidity sensor.

[0016] Preferably, the environmental influence factor corresponding to the pipette is analyzed, and the analysis result is as follows:

[0017] The environmental influence factor corresponding to the pipette is calculated by the calculation formula , , respectively, which are the weight factors of the set temperature difference between the pipette tip and the liquid to be pipetted and the humidity of the pipette tip, which represents the set allowable temperature difference, wherein , represents the temperature corresponding to the pipette tip and the temperature corresponding to the liquid to be pipetted, and s represents the set reference humidity of the pipette tip, represents the humidity corresponding to the pipette tip.

[0018] Preferably, the spring influence factor corresponding to the pipette is analyzed, and the analysis process is as follows:

[0019] The spring influence factor corresponding to the pipette is calculated by the calculation formula , , ​​The weighting factors for the number of times the spring is used and its thickness are set respectively, where K and P represent the actual number of times the spring is used and its thickness, respectively. , These represent the set reference number of spring uses and the reference thickness, respectively.

[0020] Preferably, the process of parsing the liquid aspiration information from the pipette is as follows:

[0021] Obtain the preset pipetting volume, preset suction force, and preset suction rate corresponding to the pipette, denoted as V, F, and v, respectively;

[0022] Through calculation formula The suction force corresponding to the liquid absorption information is calculated. F represents the preset suction force of the pipette, and e represents the natural constant.

[0023] Through calculation formula The suction rate corresponding to the suction information was calculated. v represents the preset reference suction rate corresponding to the pipette, and e represents the natural constant.

[0024] Preferably, the analysis and judgment of the pipetting effect is as follows:

[0025] Obtain the angle between the pipette and the vertical direction from the image corresponding to the pipette, and use it as the pipette tilt angle, denoted as . Simultaneously, obtain the corresponding pipetting volume of the pipette, denoted as V;

[0026] Through calculation formula The pipetting effect evaluation coefficient corresponding to the pipette was calculated. ,in These represent the set permissible pipette tilt angle and the set pipette volume, respectively. These are the weighting factors for the set pipette tilt angle and the set pipette volume, respectively.

[0027] If the pipetting effect evaluation coefficient corresponding to the pipette is compared with the set pipetting effect evaluation coefficient threshold, and the pipetting effect evaluation coefficient corresponding to the pipette is greater than or equal to the pipetting effect evaluation coefficient threshold, then the pipetting effect corresponding to the pipette is judged to be qualified; otherwise, the pipetting effect corresponding to the pipette is judged to be unqualified.

[0028] Preferably, the analysis process for the secondary pipetting information corresponding to the analytical pipette is as follows:

[0029] Use the tilt angle of the pipette as the pipetting adjustment angle;

[0030] Subtract the preset pipetting volume from the corresponding pipetting volume of the pipette to obtain a secondary pipetting volume corresponding to the pipette, if the secondary pipetting volume is greater than 0, it is judged that the pipetting is a liquid release, if the secondary pipetting volume is less than 0, it is judged that the pipetting is a liquid suction.

[0031] The secondary pipetting information includes the adjustment angle of the pipette and the secondary pipetting volume.

[0032] Compared with the prior art, the beneficial effects of the present application are that the high-precision quantitative pipette for biological and medical experiments and detection provided by the present application can obtain the most suitable use environment by analyzing the environmental influence factors of the pipette, and can solve the shortcomings of the prior art by splitting and screening the spring influence factors of the pipette, realize the automation and intelligent pipetting operation of the pipette, guarantee the accuracy of pipetting and improve the pipetting effect, so that the user can obtain better pipetting gun use experience, can perfectly improve the efficiency of completing the experiment, so that the reputation of the pipette can be greatly enhanced, and more people can like it, so as to better drive the sales of the pipette and obtain more profits. BRIEF DESCRIPTION OF DRAWINGS

[0033] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the drawings needed to be used in the embodiments or the prior art description will be briefly introduced below, and obviously, the drawings in the following description are only some embodiments of the present application, and for those skilled in the art, other drawings can be obtained without creative labor on the basis of these drawings.

[0034] Figure 1 The present application is a system structure connection diagram. DETAILED DESCRIPTION

[0035] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application, and obviously, the described embodiments are only some embodiments of the present application, not all embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor belong to the scope of protection of the present application.

[0036] Please refer to Figure 1 As shown in the drawings, a high-precision quantitative pipette for biological and medical experiments and detection includes an environmental information acquisition module, an environmental influence analysis module, a spring basic information acquisition module, a spring influence analysis module, a liquid suction information analysis and operation module, a pipette image acquisition module, a pipetting effect analysis module and a secondary pipetting control.

[0037] The environmental information collection module is connected with the environmental influence analysis module and the spring basic information collection module respectively, the liquid sucking information analysis module is connected with the spring influence analysis module and the secondary liquid transferring control, and the liquid sucking information analysis module is connected with the liquid transferring gun image collection module and the liquid transferring effect analysis module respectively.

[0038] The environmental information collection module is used for collecting the temperature and humidity of the gun head in the liquid transferring gun and the temperature of the liquid to be transferred.

[0039] As an optional implementation, the temperature and humidity of the gun head in the liquid transferring gun and the temperature of the liquid to be transferred in the biological medicine experiment are collected, and the collection process is as follows:

[0040] The temperature of the gun head and the liquid to be transferred in the biological medicine laboratory is collected by an electronic temperature sensor.

[0041] The humidity of the gun head in the biological medicine laboratory is collected by an electronic temperature and humidity sensor.

[0042] The environmental influence analysis module is used for analyzing the environmental influence factor of the liquid transferring gun according to the temperature and humidity of the gun head in the liquid transferring gun and the temperature of the liquid to be transferred.

[0043] As an optional implementation, the environmental influence factor of the liquid transferring gun is analyzed, and the analysis result is as follows:

[0044] The environmental influence factor of the liquid transferring gun is calculated by a calculation formula wherein , are weight factors of the set temperature difference of the gun head and the liquid to be transferred and the humidity of the gun head respectively, represents the set allowable temperature difference, wherein , represent the temperature of the gun head and the temperature of the liquid to be transferred, and s represents the set reference humidity of the gun head, represents the humidity of the gun head.

[0045] The spring basic information collection module is used for collecting the basic information of the spring in the liquid transferring gun, wherein the basic information includes the use frequency and the thickness.

[0046] It should be noted that the use frequency and the thickness of the spring in the liquid transferring gun are obtained from the liquid transferring gun management center.

[0047] The spring influence analysis module is used for analyzing the spring influence factor of the liquid transferring gun according to the basic information of the spring in the liquid transferring gun.

[0048] ​As an optional implementation, the spring influence factor corresponding to the pipette is analyzed, and the analysis process is as follows:

[0049] The corresponding spring influence factor is calculated by the calculation formula , 、 The usage frequency and thickness weight factor of the spring are respectively set as K and P, and the actual usage frequency and thickness of the spring are respectively represented as K and P. 、 The reference usage frequency and reference thickness of the spring are respectively represented as K and P.

[0050] The liquid suction information analysis and operation module is used to analyze the liquid suction information of the pipette according to the environmental influence factor and the spring influence factor corresponding to the pipette, and then perform liquid suction according to the liquid suction information of the pipette, wherein the liquid suction information includes suction force and suction speed.

[0051] As an optional implementation, the liquid suction information of the pipette is analyzed, and the analysis process is as follows:

[0052] The preset liquid suction volume, the preset suction force and the preset suction speed corresponding to the pipette are obtained, which are respectively denoted as V, F and v.

[0053] The corresponding suction force of the liquid suction information is calculated by the calculation formula , F represents the preset suction force corresponding to the pipette, and e represents the natural constant.

[0054] The corresponding suction speed of the liquid suction information is calculated by the calculation formula , v represents the preset reference suction speed corresponding to the pipette, and e represents the natural constant.

[0055] The pipette image acquisition module is used to analyze and judge the liquid suction effect according to the image corresponding to the pipette.

[0056] It should be noted that a camera is arranged in the biological and pharmaceutical experiment to acquire the image of the pipette corresponding to the biological and pharmaceutical experiment through the camera.

[0057] The liquid suction effect analysis module is used to analyze and judge the liquid suction effect according to the image corresponding to the pipette.

[0058] As an optional implementation, the liquid suction effect is analyzed and judged, and the judgment result is as follows:

[0059] The included angle between the pipette and the vertical direction is obtained from the image corresponding to the pipette, and is taken as the inclination angle of the pipette, denoted as ​​​At the same time, the pipetting volume corresponding to the pipette is acquired, and is denoted as V.

[0060] In the above, the pipetting volume corresponding to the pipette is acquired, and the specific acquisition process is as follows: a volume sensor is installed in the pipette, and then the volume of the liquid to be pipetted in the pipette is collected by the volume sensor, and is taken as the pipetting volume corresponding to the pipette.

[0061] The pipetting effect evaluation coefficient corresponding to the pipette is calculated by the calculation formula , wherein respectively represent the set allowable pipette inclination angle, the set pipetting volume corresponding to the pipette, respectively are the weight factors of the set pipette inclination angle and the set pipetting volume corresponding to the pipette.

[0062] The pipetting effect evaluation coefficient corresponding to the pipette is compared with the set pipetting effect evaluation coefficient threshold value, if the pipetting effect evaluation coefficient corresponding to the pipette is greater than or equal to the pipetting effect evaluation coefficient threshold value, it is determined that the pipetting effect corresponding to the pipette is qualified, otherwise it is determined that the pipetting effect corresponding to the pipette is unqualified.

[0063] Secondary pipetting control: when the pipetting effect is unqualified, the secondary pipetting information corresponding to the pipette is analyzed, and secondary pipetting is performed.

[0064] As an optional implementation, the analysis process of the secondary pipetting information corresponding to the pipette is as follows:

[0065] The pipette inclination angle is taken as the pipetting adjustment angle.

[0066] The pipetting volume corresponding to the pipette is subtracted by the preset pipetting volume to obtain the secondary pipetting volume corresponding to the pipette, if the secondary pipetting volume is greater than 0, it is determined that this time of pipetting is to discharge liquid, if the secondary pipetting volume is less than 0, it is determined that this time of pipetting is to suck liquid.

[0067] The secondary pipetting information includes the pipette adjustment angle and the secondary pipetting volume.

[0068] The high-precision quantitative pipette for biological and pharmaceutical tests and detection provided by the application can analyze the environmental influence factors of the pipette, obtain the most suitable required environment, and split and screen the spring influence factors of the pipette, so as to solve the deficiencies in the prior art, realize the automatic and intelligent pipetting operation of the pipette, guarantee the accuracy of pipetting and improve the pipetting effect, enable users to obtain better pipette use experience, perfectly improve the efficiency of completing experiments, greatly enhance the reputation of the pipette, and be liked by more people, so as to better drive the sales of the pipette and obtain more profits.​

[0069] Obviously, many modifications and variations of the present application are possible in light of the above teachings. It is, therefore, to be understood that within the scope of the appended claims and their equivalents, the application can be practiced otherwise than as specifically described.

Claims

1. A high-precision quantitative pipette for use in biological and medical experiments and tests, characterized in that, Comprise: Environmental information acquisition module: for collecting the temperature, humidity and the temperature corresponding to the pipette tip in the pipette gun corresponding to the liquid to be pipetted; Environmental impact analysis module: for analyzing the environmental impact factor corresponding to the pipette gun according to the temperature, humidity and the temperature corresponding to the pipette tip in the pipette gun corresponding to the liquid to be pipetted; Spring basic information acquisition module: for collecting the basic information corresponding to the spring in the pipette gun, wherein the basic information includes the number of uses and the thickness; Spring influence analysis module: for analyzing the spring influence factor corresponding to the pipette gun according to the basic information corresponding to the spring in the pipette gun; Liquid suction information analysis and operation module: for analyzing the liquid suction information of the pipette gun according to the environmental impact factor and the spring influence factor corresponding to the pipette gun, and then performing liquid suction according to the liquid suction information of the pipette gun, wherein the liquid suction information includes suction force and suction speed; Pipette image acquisition module: for collecting the image corresponding to the pipette gun after the pipette completes liquid suction; Pipette effect analysis module: for judging the pipette effect according to the image corresponding to the pipette gun; Secondary pipetting control: when the pipette effect is unqualified, analyze the secondary pipetting information corresponding to the pipette gun and perform secondary pipetting.

2. The high-precision quantitative pipette gun for biological medicine test and detection according to claim 1, characterized in that, The temperature, humidity and the temperature corresponding to the pipette tip in the pipette gun in the biological medicine experiment are collected, and the collection process is as follows: Place an electronic temperature sensor in the biological medicine experiment, and then collect the temperature information of the pipette tip and the liquid to be pipetted in the biological medicine laboratory through the electronic temperature sensor, and obtain the set temperature; Place an electronic humidity sensor in the biological medicine experiment, and then collect the humidity corresponding to the pipette tip in the biological medicine laboratory through the electronic temperature and humidity sensor.

3. The high-precision quantitative pipette gun for biological medicine test and detection of claim 1, wherein The environmental impact factor corresponding to the pipette gun is analyzed, and the analysis result is as follows: The environmental impact factor corresponding to the pipette gun is calculated by the formula The environmental impact factor corresponding to the pipette gun is calculated by the formula Wherein , The weight factors corresponding to the temperature difference between the set gun head and the liquid to be transferred, and the humidity of the gun head, respectively, Indicates the set allowable temperature difference, wherein , Indicates the temperature corresponding to the gun head and the temperature corresponding to the liquid to be transferred, and s indicates the set reference humidity of the gun head, Indicates the humidity corresponding to the gun head.

4. The high-precision quantitative pipette for biomedical testing and detection as described in claim 1, characterized in that, The spring influence factor corresponding to the pipette gun is analyzed, and the analysis process is as follows: The spring influence factor is calculated by the following formula The corresponding spring influence factor is calculated , , The weight factors of the number of uses and the thickness of the spring are respectively set, K and P represent the actual number of uses and the thickness of the spring, , The reference number of uses and the reference thickness of the spring are respectively represented.

5. The high-precision quantitative pipette gun for biological medicine test and detection of claim 1, wherein, The liquid suction information of the pipette gun is analyzed, and the analysis process is as follows: Get the preset pipetting volume, preset suction force and preset suction speed corresponding to the pipette gun, respectively recorded as V, F and v; The corresponding suction information is calculated by the formula The corresponding suction information is calculated by the formula , F represents the preset suction force corresponding to the pipette, and e represents the natural constant. The corresponding liquid suction information is calculated by the formula The corresponding suction speed of the liquid suction information is calculated , v represents the preset reference suction speed corresponding to the pipette, and e represents the natural constant.

6. The high-precision quantitative pipette gun for biological medicine test and detection of claim 1, wherein, The pipette effect is judged, and the judgment result is as follows: An angle between the pipette and the vertical direction is obtained from the image corresponding to the pipette and is taken as the pipette tilt angle, denoted as At the same time, a pipetting volume corresponding to the pipette is obtained from the image corresponding to the pipette and is denoted as V. The pipetting effect evaluation coefficient corresponding to the pipette is calculated by the formula The pipetting effect evaluation coefficient corresponding to the pipette is calculated by the formula , wherein respectively represent the set permitted pipette inclination angle, the set pipetting volume corresponding to the pipette, respectively are the weight factors of the set pipette inclination angle and the set pipetting volume corresponding to the pipette. The pipette effect evaluation coefficient corresponding to the pipette gun is compared with the set pipette effect evaluation coefficient threshold value, if the pipette effect evaluation coefficient corresponding to the pipette gun is greater than or equal to the pipette effect evaluation coefficient threshold value, it is judged that the pipette effect corresponding to the pipette gun is qualified, otherwise it is judged that the pipette effect corresponding to the pipette gun is unqualified.

7. A high-precision quantitative pipette for biomedical testing and detection as described in claim 1, characterized in that, The secondary pipetting information corresponding to the pipette gun is analyzed, and the analysis process is as follows: The inclination angle of the pipette gun is taken as the pipetting adjustment angle; The pipetting volume corresponding to the pipette gun is subtracted from the preset pipetting volume to obtain the secondary pipetting volume corresponding to the pipette gun, if the secondary pipetting volume is greater than 0, it is judged that this time of pipetting is to discharge liquid, if the secondary pipetting volume is less than 0, it is judged that this time of pipetting is to suck liquid; The secondary pipetting information includes the pipette adjustment angle and the secondary pipetting volume.

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