Aromatic Chinese herbal composition for relieving dysmenorrhea, preparation method and application thereof

Abstract

The application provides a kind of aromatic Chinese herbal medicine composition for relieving dysmenorrhea, comprising the following components: Bai Zhi, clove, mugwort leaf, fennel, shanzhai, cassia, angelica, chuanxiong, rhizoma cyperi, costus, rose, osmanthus, styrax.The application selects 13 kinds of aromatic Chinese herbal medicine according to the symptoms of cold coagulation and blood stasis type dysmenorrhea, further makes a sachet for relieving cold coagulation and blood stasis type dysmenorrhea, and intervenes the patients with cold coagulation and blood stasis type dysmenorrhea, which shows that the sachet can relieve abdominal pain and dysmenorrhea accompanying symptoms of the patients, reduce the pain disaster level, and alleviate negative emotions, highlights the potential of various Chinese herbal medicine aromatherapy as a natural therapy for relieving dysmenorrhea, and the non-invasive and convenient multiple aromatic Chinese herbal medicine inhalation therapy has excellent tolerance.The application expands the application range of aromatic Chinese herbal medicine and aromatherapy, promotes the understanding and application of traditional Chinese medicine principles in modern medical practice, and helps to actively promote the inheritance and development of traditional Chinese medicine culture.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine technology, and more specifically, relates to an aromatic herbal composition for relieving dysmenorrhea, its preparation method and application. Background Technology

[0002] Dysmenorrhea is a common gynecological condition whose symptoms can significantly impact daily activities, potentially leading to decreased sleep quality, negative emotions, increased medical costs, and an increased risk of chronic pain and central nervous system sensitivity. Common pain relief options recommended by Western medicine include oral nonsteroidal anti-inflammatory drugs (NSAIDs) and oral contraceptives. While conventional Western methods can quickly relieve dysmenorrhea symptoms, they are prone to relapse and carry potential side effects such as drug dependence, gastrointestinal discomfort, and allergies. Traditional Chinese medicine (TCM) treats dysmenorrhea based on syndrome differentiation, including six types: cold stagnation and blood stasis, qi stagnation and blood stasis, qi and blood deficiency, yang deficiency and internal cold, liver and kidney deficiency, and damp-heat accumulation. Among dysmenorrhea sufferers, the cold stagnation and blood stasis type is predominant. Treatment for this type typically involves conventional TCM methods such as oral herbal decoctions, acupuncture, and acupoint application, which have shown positive effects in improving dysmenorrhea symptoms. However, some university students prefer non-invasive complementary and alternative medicine therapies, such as aromatherapy, due to the bitterness of traditional Chinese medicine, the pain of acupuncture, and the risk of allergic reactions at acupoints.

[0003] Currently, aromatherapy primarily relies on the use of aromatic essential oils to relieve menstrual cramps. However, some essential oils are phototoxic, sensitizing, and irritating, and the uncertainty of their optimal dilution concentration may pose potential risks to patients, especially with topical application. In contrast, aromatic herbs can be classified according to their medicinal properties and effects, such as aromatic warming herbs, aromatic dampness-resolving herbs, and aromatic mind-opening herbs. Specifically, aromatic warming herbs have the effect of warming the meridians, promoting blood circulation, and relieving pain, helping to alleviate menstrual cramps; aromatic dampness-resolving herbs have the effect of strengthening the spleen and stomach, aiding digestion, and helping to relieve gastrointestinal discomfort caused by menstrual cramps; aromatic mind-opening herbs have an invigorating effect, helping to alleviate negative emotions associated with menstrual discomfort. Aromatherapy using various aromatic herbs may have the potential to promote meridian opening, blood circulation, and promote natural relief of menstrual cramps.

[0004] University students face unique physiological, psychological, and social challenges, while also possessing greater autonomy and independence, stronger health awareness, and a positive attitude towards participating in health-related activities. Targeted treatment based on TCM syndrome differentiation is a key factor influencing treatment efficacy. Among university students, congenital deficiencies or acquired malnutrition (such as excessive consumption of cold foods and beverages, prolonged exposure to cold and damp environments, wearing clothing that exposes the abdomen and ankles, and exposure to external cold during menstruation) make them susceptible to invasion by cold pathogens. This pathogenesis originates from kidney yang deficiency, characterized by cold stagnation and blood stasis. Therefore, it is essential to provide a non-invasive, gentle, and comfort-oriented aromatic herbal composition for dysmenorrhea caused by cold stagnation and blood stasis. Summary of the Invention

[0005] The purpose of this invention is to overcome the above-mentioned defects and deficiencies in the prior art and to provide an aromatic herbal composition for relieving dysmenorrhea.

[0006] A second objective of the present invention is to provide a method for preparing the aromatic herbal composition.

[0007] A third object of the present invention is to provide the application of the aromatic herbal composition.

[0008] The above-mentioned objective of this invention is achieved through the following technical solution:

[0009] An aromatic herbal composition for relieving menstrual cramps, comprising the following components: Angelica dahurica, clove, Artemisia argyi, fennel, galangal, cinnamon, Angelica sinensis, Ligusticum chuanxiong, Cyperus rotundus, Costus root, rose, osmanthus, and styrax.

[0010] The aromatic herbal composition of this invention is based on the principles of traditional Chinese medicine (TCM) syndrome differentiation and treatment. It utilizes 13 aromatic herbs specifically for dysmenorrhea, including cloves, mugwort, fennel, and cinnamon, which have warming and tonifying effects on the kidneys and dispelling cold; and angelica dahurica, angelica sinensis, chuanxiong rhizome, costus root, cyperus rhizome, and rose, which have blood-activating, stasis-removing, and pain-relieving effects. Additionally, it includes galangal, styrax, and osmanthus, which have appetite-stimulating, nausea-relieving, calming, and tranquilizing effects. The aromatic properties of these 13 herbs can be used for aromatherapy to alleviate dysmenorrhea.

[0011] Angelica dahurica, the dried root of the plant Angelica dahurica (family Apiaceae), is pungent, warm, and aromatic, and enters the lung and stomach meridians. Its traditional effects include dispelling wind and relieving exterior syndromes, reducing swelling and draining pus, and drying dampness and stopping leukorrhea; it is commonly used to treat pelvic inflammatory disease and headaches. Modern research has shown that an in vitro decoction of Angelica dahurica has a certain inhibitory effect on Shigella and Pseudomonas aeruginosa. This invention uses Angelica dahurica as a component of a sachet for relieving dysmenorrhea, aiming to utilize its traditional aromatic and warming properties, its wind-dispelling and exterior-releasing effects, and its modern anti-inflammatory and analgesic effects to warm the meridians, promote blood circulation, and relieve pain, thus alleviating abdominal pain and headaches associated with dysmenorrhea.

[0012] Clove, the dried flower bud of the clove tree (Syzygium aromaticum), is pungent, warm, and aromatic, and enters the spleen, stomach, and kidney meridians. Traditional uses include warming the kidneys and tonifying yang, warming the middle jiao and relieving nausea and vomiting; it is often used to treat abdominal pain due to cold, nausea, and vomiting. Modern research shows that its main components, clove oil and acetyleugenol, can alleviate nausea and vomiting, and exhibit inhibitory effects against Staphylococcus aureus and Shigella spp. in vitro. This invention uses clove as a component of a sachet for relieving menstrual cramps, aiming to utilize its aromatic and warming properties, its ability to dispel dampness, its kidney-warming and yang-tonifying effects, its ability to warm the middle jiao and relieve nausea and vomiting, and its modern anti-inflammatory effects. It also aims to invigorate the spleen and stomach, aid digestion, and relieve abdominal pain and systemic symptoms associated with menstrual cramps, such as nausea and vomiting.

[0013] Artemisia argyi, the dried leaves of the herbaceous plant Artemisia argyi (family Asteraceae), is bitter, pungent, warm, and aromatic, and enters the liver, spleen, and kidney meridians. Traditional medicinal effects include dispelling cold and relieving pain, warming the meridians and promoting blood circulation. It is often used in combination with Angelica sinensis and cinnamon to treat dysmenorrhea and irregular menstruation in women. Modern in vitro studies have shown that the volatile oil of Artemisia argyi has a significant inhibitory effect on various bacteria and fungi. This invention uses Artemisia argyi as a component of a sachet for relieving dysmenorrhea, aiming to utilize its aromatic and warming properties, its ability to dispel cold and relieve pain, warm the meridians and promote blood circulation, and its modern anti-inflammatory effects to alleviate abdominal pain associated with dysmenorrhea.

[0014] Fennel, the fruit of the fennel plant (Apiaceae family), is pungent, warm, and aromatic, and enters the liver, kidney, spleen, and stomach meridians. Traditionally, it is used to warm the kidneys and dispel cold, regulate qi and harmonize the stomach, and is often used in combination with angelica and chuanxiong to treat menstrual cramps, vomiting, and poor appetite. Modern research indicates that its volatile oil has antibacterial properties. This invention uses fennel as a component of a sachet for relieving menstrual cramps, aiming to utilize its aromatic, warming, and dampness-dispelling properties, its kidney-warming, cold-dispelling, qi-regulating, and stomach-harmonizing effects, as well as its modern anti-inflammatory properties, to alleviate abdominal pain and systemic symptoms associated with menstrual cramps, such as nausea and vomiting.

[0015] Kaempferia galanga, the rhizome of the ginger family herbaceous plant Kaempferia galanga, is pungent, warm, and aromatic, and enters the spleen and stomach meridians. Traditionally, it is used to warm the middle jiao (digestive system), promote digestion, remove blood stasis, and reduce swelling, often treating vomiting and diarrhea due to cold and dampness. Modern research shows that its volatile oil has varying degrees of inhibitory effects on common pathogenic fungi. This invention uses Kaempferia galanga as a component of a sachet for relieving menstrual cramps, aiming to utilize its aromatic, warming, and dampness-resolving properties, its ability to warm the middle jiao and promote digestion, and its modern anti-inflammatory effects to relieve abdominal pain and systemic symptoms associated with menstrual cramps, such as nausea and vomiting.

[0016] Cinnamon, the dried bark of the evergreen cinnamon tree (Cinnamomum cassia), is pungent, sweet, very hot, and aromatic, and enters the kidney, spleen, liver, and heart meridians. Traditionally, it is used to tonify yang, dispel cold and relieve pain, and warm the meridians and promote blood circulation, often for the treatment of dysmenorrhea and lower back and knee pain. Modern research shows that its volatile oil has inhibitory and anti-inflammatory effects on carbon monoxide and prostaglandin-induced uterine smooth muscle contractions. This invention uses cinnamon as a component of a sachet for relieving dysmenorrhea, aiming to utilize its aromatic and warming properties, tonifying yang, dispelling cold and relieving pain, warming the meridians and promoting blood circulation, as well as its modern hormone-regulating and anti-inflammatory effects to alleviate abdominal pain associated with dysmenorrhea.

[0017] Angelica sinensis, the root of the herbaceous plant Angelica sinensis (family Apiaceae), is pungent, sweet, warm, and aromatic, and enters the liver, spleen, and heart meridians. Its traditional effects include promoting blood circulation and relieving pain, regulating menstruation, nourishing blood, and moistening the intestines to relieve constipation. It is commonly used to treat abdominal pain, irregular menstruation, and pelvic inflammatory disease. Modern research has shown that its volatile oil has analgesic, anti-inflammatory, and antibacterial effects. This invention uses cinnamon as a component of a sachet for relieving menstrual cramps, aiming to utilize its aromatic and warming properties, its ability to promote blood circulation and relieve pain, and its modern analgesic, anti-inflammatory, and antibacterial effects to alleviate abdominal pain associated with menstrual cramps.

[0018] Chuanxiong (Ligusticum striatum), the rhizome of the umbellatus herbaceous plant, is pungent, warm, and aromatic, and enters the liver, gallbladder, and pericardium meridians. Traditionally, it is used to invigorate blood circulation, promote qi flow, dispel wind, and relieve pain. It is often used in combination with Angelica sinensis, Artemisia argyi, and Paeonia lactiflora to treat dysmenorrhea, amenorrhea, and headaches. Modern research has shown that its volatile oil has inhibitory and antibacterial effects on oxytocin-induced uterine smooth muscle. This invention uses Chuanxiong as a component of a dysmenorrhea relief sachet, aiming to utilize its aromatic and warming properties, its ability to invigorate blood circulation, promote qi flow, dispel wind, and relieve pain, as well as its modern hormone-regulating, anti-inflammatory, and antibacterial effects to alleviate abdominal pain and systemic symptoms associated with dysmenorrhea, such as headaches.

[0019] Cyperus rotundus, the rhizome of the herbaceous plant Cyperus rotundus, is pungent, slightly bitter, sweet, and neutral in nature, and enters the liver and triple burner meridians. Traditionally, it is used to regulate menstruation and relieve pain, soothe the liver and relieve depression. It is often used in combination with Angelica sinensis, Paeonia lactiflora, and Carthamus tinctorius to treat irregular menstruation, dysmenorrhea, breast tenderness, amenorrhea, and depression. Modern research shows that its volatile oil has inhibitory effects on Staphylococcus aureus and fungi. This invention uses Cyperus rotundus as a component of a sachet for relieving dysmenorrhea, aiming to utilize its effects of regulating menstruation and relieving pain, soothing the liver and relieving depression, as well as its modern anti-inflammatory and antibacterial properties, to alleviate systemic symptoms such as abdominal pain, breast tenderness, and negative emotions associated with dysmenorrhea.

[0020] Costus root, the root of the herbaceous plant Costus root (family Asteraceae), is pungent, bitter, warm, and aromatic, and enters the liver, spleen, stomach, and large intestine meridians. Traditional uses include regulating qi and relieving pain, strengthening the spleen and promoting digestion, and soothing the liver and gallbladder; it is commonly used to treat diarrhea. Modern research shows that its volatile oil has inhibitory effects on Staphylococcus aureus and Streptococcus. This invention uses Costus root as a component of a sachet for relieving menstrual cramps, aiming to utilize its aromatic and warming properties, its qi-regulating and pain-relieving effects, and its modern anti-inflammatory and antibacterial properties to alleviate abdominal pain and systemic symptoms associated with menstrual cramps, such as diarrhea.

[0021] Rose, the flower bud of the rose bush (Rosa rugosa), is sweet, slightly bitter, and warm in nature, with a fragrant aroma, and enters the liver and spleen meridians. Traditionally, it is used to invigorate blood circulation, regulate menstruation, and relieve depression, often treating irregular menstruation, dysmenorrhea, and breast tenderness. Modern research shows that its volatile oil has an inhibitory effect on adrenocortical hormone-induced uterine smooth muscle contraction. This invention uses rose as a component of a dysmenorrhea-relieving sachet, aiming to utilize its fragrant and warming medicinal properties, its effects of invigorating blood circulation, regulating menstruation, and relieving depression, as well as its modern hormone-regulating effects, to enhance the pleasant floral aroma of traditional Chinese medicine and alleviate systemic symptoms such as abdominal pain, breast tenderness, and negative emotions associated with dysmenorrhea.

[0022] Osmanthus, the flower of an evergreen shrub in the Oleaceae family, is pungent, warm, and aromatic, and enters the lung, liver, and stomach meridians. Traditional uses include dispelling cold and stagnation, resolving phlegm and relieving cough. It is often used in combination with motherwort, mugwort, and rose for the treatment of amenorrhea and abdominal pain. Modern research has shown that its volatile oil has antioxidant and anti-inflammatory effects. This invention uses rose petals as a component of a sachet for relieving menstrual cramps, aiming to utilize its aromatic and warming medicinal properties, its ability to dispel cold and stagnation, and its modern antioxidant and anti-inflammatory effects. It also enhances the pleasant floral aroma of traditional Chinese medicine, relieving abdominal pain and negative emotions associated with menstrual cramps.

[0023] Styrax, the resin secreted by the styrax tree (Hamamellaceae family), is pungent, warm, and aromatic, and enters the heart and spleen meridians. Traditionally, it is used to open the orifices, refresh the mind, dispel foul odors, and relieve pain, often in the treatment of angina pectoris and coma. Modern research indicates its local anti-inflammatory effects. This invention uses styrax as a component of a sachet for relieving menstrual cramps, aiming to utilize its aromatic and orifice-opening properties, its ability to refresh the mind, and its modern antioxidant and anti-inflammatory effects to alleviate the negative emotions and systemic symptoms associated with menstrual cramps and prevent fainting caused by exacerbated abdominal pain.

[0024] The mechanism of dysmenorrhea is related to endocrine hormones such as prostaglandins, oxytocin, nitric oxide, and adrenaline, as well as inflammation and oxidative stress. Reactive oxygen species generated by inflammatory responses are a major source of oxidative damage. Therefore, the hormone-regulating, anti-inflammatory, and antioxidant capabilities of traditional Chinese medicine play an important role in alleviating dysmenorrhea symptoms. Modern pharmacological studies have shown that cinnamaldehyde and rose aldehyde isolated from Ligusticum chuanxiong and cinnamon, respectively, have inhibitory effects on uterine smooth muscle contractions induced by oxytocin, nitric oxide, prostaglandins, and adrenaline. Cyperus rotundus can also inhibit uterine smooth muscle contractions and has significant analgesic and sedative effects. In addition, Angelica sinensis can enhance blood flow, reduce pelvic congestion, and nourish the vagina. Acetyleugenol and methyleugenol isolated from cloves, organic acids and terpenes isolated from Artemisia argyi, ionones, flavonoids, and polyphenols, the main components of Osmanthus fragrans, fennel, and styrax have antioxidant and anti-inflammatory effects. Aucklandia lappa, Kaempferia galanga, and Angelica dahurica have broad-spectrum antioxidant, anti-inflammatory, analgesic, vasodilatory, and sedative pharmacological activities. Existing research indicates that ion channels and G protein receptors interact in connecting and processing pain and smell, and that the same shared areas in the brain can process pain and olfactory information. In addition, inhalation therapy allows the active ingredients of drugs to enter the bloodstream through the respiratory system, thereby exerting pharmacological effects, providing a basis for inhalation therapy in aromatherapy to relieve dysmenorrhea.

[0025] Furthermore, the aromatic herbal composition comprises the following components in parts by weight: 3-7 parts Angelica dahurica, 4-6 parts clove, 3-7 parts Artemisia argyi, 4-6 parts fennel, 3-7 parts Kaempferia galanga, 8-12 parts cinnamon, 8-12 parts Angelica sinensis, 8-12 parts Ligusticum chuanxiong, 8-12 parts Cyperus rotundus, 8-12 parts Aucklandia lappa, 13-17 parts Rosa rugosa, 14-16 parts Osmanthus fragrans, and 0.05-0.15 parts Styrax benzoin.

[0026] Preferably, the aromatic herbal composition comprises the following components in parts by weight: 4-6 parts Angelica dahurica, 4-6 parts clove, 4-6 parts Artemisia argyi, 4-6 parts fennel, 4-6 parts Kaempferia galanga, 9-11 parts cinnamon, 9-11 parts Angelica sinensis, 9-11 parts Ligusticum chuanxiong, 9-11 parts Cyperus rotundus, 9-11 parts Aucklandia lappa, 14-16 parts Rosa rugosa, 14-16 parts Osmanthus fragrans, and 0.08-0.12 parts Styrax benzoin.

[0027] Preferably, the aromatic herbal composition comprises the following components in parts by weight: 5-6 parts Angelica dahurica, 5-6 parts clove, 5-6 parts Artemisia argyi, 5-6 parts fennel, 5-6 parts Kaempferia galanga, 10-11 parts cinnamon, 10-11 parts Angelica sinensis, 10-11 parts Ligusticum chuanxiong, 10-11 parts Cyperus rotundus, 10-11 parts Aucklandia lappa, 15-16 parts Rosa rugosa, 15-16 parts Osmanthus fragrans, and 0.1-0.12 parts Styrax benzoin.

[0028] Preferably, the aromatic herbal composition comprises the following components in parts by weight: 5-6 parts Angelica dahurica, 5-6 parts clove, 5-6 parts Artemisia argyi, 5-6 parts fennel, 5-6 parts Kaempferia galanga, 10-11 parts cinnamon, 10-11 parts Angelica sinensis, 10-11 parts Ligusticum chuanxiong, 10-11 parts Cyperus rotundus, 10-11 parts Aucklandia lappa, 15 parts rose, 15 parts Osmanthus fragrans, and 0.1 parts Styrax benzoin.

[0029] Preferably, the aromatic herbal composition comprises the following components in parts by weight: 5-6 parts Angelica dahurica, 5-6 parts clove, 5-6 parts Artemisia argyi, 5-6 parts fennel, 5-6 parts Kaempferia galanga, 10 parts cinnamon, 10 parts Angelica sinensis, 10 parts Ligusticum chuanxiong, 10 parts Cyperus rotundus, 10 parts Aucklandia lappa, 15 parts rose, 15 parts Osmanthus fragrans, and 0.1 parts Styrax benzoin.

[0030] Most preferably, the aromatic herbal composition comprises the following components in parts by weight: 5 parts Angelica dahurica, 5 parts clove, 5 parts Artemisia argyi, 5 parts fennel, 5 parts Kaempferia galanga, 10 parts cinnamon, 10 parts Angelica sinensis, 10 parts Ligusticum chuanxiong, 10 parts Cyperus rotundus, 10 parts Aucklandia lappa, 15 parts rose, 15 parts Osmanthus fragrans, and 0.1 parts Styrax benzoin.

[0031] The present invention also provides a method for preparing any of the above-mentioned herbal compositions for relieving dysmenorrhea, the steps of which are to grind Angelica dahurica, clove, Artemisia argyi, fennel, galangal, cinnamon, Angelica sinensis, Ligusticum chuanxiong, Cyperus rotundus, Costus root, rose, osmanthus, and styrax into powder, and weigh out the corresponding weight proportions of the herbal powder and mix them together.

[0032] The present invention also provides the use of any of the above-described aromatic herbal compositions in the preparation of aromatherapy products for relieving dysmenorrhea.

[0033] Furthermore, the dysmenorrhea described is a type of dysmenorrhea caused by cold stagnation and blood stasis.

[0034] The present invention also provides an aromatherapy product for relieving menstrual cramps, the product comprising any of the aromatic herbal compositions described above.

[0035] Furthermore, the product is a traditional Chinese medicine sachet.

[0036] Preferably, the product is a sachet made of cotton or linen and containing the aromatic herbal composition.

[0037] Preferably, the product is an aromatic herbal composition prepared by the above method, which is packaged into a single-layer breathable sachet made of cotton or linen, and used as an aromatherapy treatment for dysmenorrhea patients during menstruation by inhaling the sachet.

[0038] Compared with the prior art, the present invention has the following beneficial effects:

[0039] This invention provides an aromatic herbal composition for relieving dysmenorrhea. Based on the symptoms of dysmenorrhea caused by cold stagnation and blood stasis, 13 aromatic herbs were specifically selected and further formulated into a sachet for this type of dysmenorrhea. Intervention in patients with this type of dysmenorrhea showed that the sachet could relieve abdominal pain and accompanying symptoms, reduce the catastrophic level of pain, and soothe negative emotions. This highlights the potential of various herbal aromatherapy methods as natural remedies for dysmenorrhea, and the non-invasive and convenient inhalation therapy of various aromatic herbs has excellent tolerability. This invention expands the application scope of aromatic herbs and aromatherapy, promotes the understanding and application of traditional Chinese medicine principles in modern medical practice, and contributes to the active advancement of the inheritance and development of traditional Chinese medicine culture. Attached Figure Description

[0040] Figure 1 The average VAS values ​​were analyzed for menstrual cycles before intervention, and for interventions 1, 2, and 3. Detailed Implementation

[0041] The present invention will be further described below with reference to the accompanying drawings and specific embodiments, but the embodiments do not limit the present invention in any way. Unless otherwise specified, the reagents, methods and equipment used in the present invention are conventional reagents, methods and equipment in this technical field.

[0042] Unless otherwise specified, all reagents and materials used in the following examples are commercially available.

[0043] Example 1

[0044] Take 13 kinds of aromatic Chinese herbs and grind them into fine powder. The following amounts of each herb are weighed: 5g of Angelica dahurica, 5g of clove, 5g of Artemisia argyi, 5g of fennel, 5g of Kaempferia galanga, 10g of cinnamon, 10g of Angelica sinensis, 10g of Ligusticum chuanxiong, 10g of Cyperus rotundus, 10g of Aucklandia lappa, 15g of rose, 15g of Osmanthus fragrans, and 0.1g of Styrax benzoin. Put each herb into a 13cm×18cm sachet and mix them evenly. Seal the sachet to prevent the powder from leaking out. Each sachet contains 105.1g of powder.

[0045] Example 2

[0046] Take 13 kinds of aromatic Chinese herbs and grind them into a fine powder. The weight of each herb is as follows: Angelica dahurica 7g, clove 6g, Artemisia argyi 7g, fennel 6g, galangal 7g, cinnamon 12g, Angelica sinensis 12g, Ligusticum chuanxiong 12g, Cyperus rotundus 12g, Aucklandia lappa 12g, rose 17g, Osmanthus fragrans 16g, and Styrax 0.15g. Put each herb into a 13cm×18cm sachet and mix them evenly. Seal the sachet to prevent the powder from leaking out. Each sachet contains 126.15g.

[0047] Example 3

[0048] Take 13 kinds of aromatic Chinese herbs and grind them into a fine powder. The following amounts of each herb are weighed: 3g of Angelica dahurica, 4g of clove, 3g of Artemisia argyi, 4g of fennel, 3g of Kaempferia galanga, 8g of cinnamon, 8g of Angelica sinensis, 8g of Ligusticum chuanxiong, 8g of Cyperus rotundus, 8g of Aucklandia lappa, 13g of rose, 14g of Osmanthus fragrans, and 0.05g of Styrax benzoin. Put each herb into a 13cm×18cm sachet and mix them evenly. Seal the sachet to prevent the powder from leaking out. Each sachet contains 84.5g of herbs.

[0049] Example 4

[0050] Thirteen aromatic Chinese herbs were ground into a fine powder. The following amounts of each herb were weighed: 6g of Angelica dahurica, 6g of cloves, 6g of Artemisia argyi, 6g of fennel, 6g of Kaempferia galanga, 11g of cinnamon, 11g of Angelica sinensis, 11g of Ligusticum chuanxiong, 11g of Cyperus rotundus, 11g of Aucklandia lappa, 16g of rose, 16g of Osmanthus fragrans, and 0.12g of Styrax benzoin. Each herb was placed into a 13cm×18cm sachet and mixed evenly. The sachet was then sealed to prevent leakage. Each sachet contained 117.12g of the powder.

[0051] Example 5

[0052] Take 13 kinds of aromatic Chinese herbs and grind them into fine powder. The weight of each herb is as follows: 4g of Angelica dahurica, 4g of clove, 4g of Artemisia argyi, 4g of fennel, 4g of galangal, 9g of cinnamon, 9g of Angelica sinensis, 9g of Ligusticum chuanxiong, 9g of Cyperus rotundus, 9g of Aucklandia lappa, 14g of rose, 14g of Osmanthus fragrans, and 0.08g of Styrax benzoin. Put each herb into a 13cm×18cm sachet and mix them evenly. Seal the sachet to prevent the powder from leaking out. Each sachet contains 93.08g of powder.

[0053] Example 6

[0054] Take 13 kinds of aromatic Chinese herbs and grind them into a fine powder. The following amounts of each herb are weighed: 6g of Angelica dahurica, 6g of clove, 6g of Artemisia argyi, 6g of fennel, 6g of Kaempferia galanga, 11g of cinnamon, 11g of Angelica sinensis, 11g of Ligusticum chuanxiong, 11g of Cyperus rotundus, 11g of Aucklandia lappa, 15g of rose, 15g of Osmanthus fragrans, and 0.1g of Styrax benzoin. Put each herb into a 13cm×18cm sachet and mix them evenly. Seal the sachet to prevent the powder from leaking out. Each sachet contains 115.1g of powder.

[0055] Example 7

[0056] Take 13 kinds of aromatic Chinese herbs and grind them into a fine powder. The following amounts of each herb are weighed: 6g of Angelica dahurica, 6g of clove, 6g of Artemisia argyi, 6g of fennel, 6g of Kaempferia galanga, 10g of cinnamon, 10g of Angelica sinensis, 10g of Ligusticum chuanxiong, 10g of Cyperus rotundus, 10g of Aucklandia lappa, 15g of rose, 15g of Osmanthus fragrans, and 0.1g of Styrax benzoin. Put each herb into a 13cm×18cm sachet and mix them evenly. Seal the sachet to prevent the powder from leaking out. Each sachet contains 110.1g of powder.

[0057] Test Example 1

[0058] The sachets prepared in Examples 1-7 and a placebo were used to intervene in 94 subjects for three menstrual cycles, and the results were evaluated using the VAS (Visual Analogue Scale).

[0059] To eliminate the influence of food or other people's perfume scents on the sachet's aroma, hang the sachet on the side of your body, approximately 30 cm above your nose, at the same height, while sleeping at night. The intervention period is from 11:00 PM to 7:00 AM the following morning (8 hours). The next morning, store the sachets in a sealed 16cm x 24cm bag, adding two packets of food-grade desiccant to prevent the aroma from dissipating quickly, the active ingredients from evaporating, or from becoming damp or contaminated by other objects. To ensure the sachet maintains its function and effectiveness, replace it every 4 weeks, and continue using it during menstruation.

[0060] Example 1: The therapeutic results of the sachet are as follows Figure 1As shown, the sachet intervention was significantly more effective than the placebo, and the VAS score gradually decreased with the progress of the intervention. Meanwhile, Example 1 showed the best effect in relieving dysmenorrhea caused by cold stagnation and blood stasis, while Examples 7, 6, 4, 5, 2, and 3 showed progressively lower effectiveness compared to Example 1, but were still significantly better than the placebo. These results indicate that the sachets of Examples 1-7 of this invention can effectively relieve dysmenorrhea symptoms caused by cold stagnation and blood stasis in college students, alleviating abdominal pain and accompanying symptoms, reducing pain catastrophizing levels, and soothing negative emotions. This highlights the potential of various traditional Chinese medicine aromatherapy therapies as natural treatments for dysmenorrhea, and the non-invasive and convenient inhalation therapy of various aromatic traditional Chinese medicines has excellent tolerability. With the increasing research on complementary and alternative medicine therapies, integrating traditional and modern medicine practices can bring about more comprehensive and personalized healthcare approaches, ultimately improving the quality of life for patients with dysmenorrhea and other gynecological diseases. Expanding the application scope of aromatic traditional Chinese medicine and aromatherapy promotes the understanding and application of traditional Chinese medicine principles in modern medical practice and actively advances the inheritance and development of traditional Chinese medicine culture.

[0061] Comparative Example 1

[0062] According to Table 1, different components of the herbal composition were weighed, ground into powder, and then placed into 13cm×18cm sachets. The powder was then mixed evenly and sealed to prevent leakage. This is different from Example 1, as each sachet lacks one aromatic herbal ingredient. Based on the medicinal properties of the herbal compositions, the herbal sachets prepared with different components have reduced efficacy compared to Example 1 and are unable to effectively relieve dysmenorrhea caused by cold stagnation and blood stasis. If Angelica dahurica is missing from Composition 1, the synergistic effect of the herbal composition on dysmenorrhea caused by cold stagnation and blood stasis will be weakened, affecting the pain relief effect of dysmenorrhea caused by cold stagnation and blood stasis. If clove is missing from Composition 2, the warming and spleen-invigorating effects of the herbal composition will be weakened, affecting its symptom relief effect on dysmenorrhea caused by cold stagnation and blood stasis. If Artemisia argyi is missing from Composition 3, the kidney-warming and cold-dispelling effects of the herbal composition will be weakened, affecting the relief of dysmenorrhea caused by kidney yang deficiency. If fennel is removed from Composition 4, the synergistic effect of the kidney-warming and cold-dispelling effects of the herbal composition will be affected. If galangal is removed from Composition 5, the effects of the herbal composition on promoting blood circulation, removing blood stasis, warming the middle and promoting digestion will be affected.

[0063] Table 1. Components of Different Traditional Chinese Medicine Combinations (Unit: g)

[0064] Components Composition 1 Composition 2 Composition 3 Composition 4 Composition 5 Angelica dahurica - 5 5 5 5 clove 5 - 5 5 5 mugwort 5 5 - 5 5 Fennel 5 5 5 - 5 Shannai 5 5 5 5 - Cinnamon 10 10 10 10 10 Angelica sinensis 10 10 10 10 10 Chuanqiong 10 10 10 10 10 Cyperus rotundus 10 10 10 10 10 Woody Scent 10 10 10 10 10 roses 15 15 15 15 15 Osmanthus fragrans 15 15 15 15 15 Styrax 0.1 0.1 0.1 0.1 0.1 total 100.1 100.1 100.1 100.1 100.1

[0065] Comparative Example 2

[0066] Grind angelica dahurica, cloves, mugwort, fennel, galangal, rose, osmanthus, and styrax into powder. Take the following weights of each component: 5g angelica dahurica, 5g cloves, 5g mugwort, 5g fennel, 5g galangal, 15g rose, 15g osmanthus, and 0.1g styrax. Place these components into a sachet, mix thoroughly, and seal to prevent leakage. Compared to Example 1, this herbal sachet lacks five components: cinnamon, angelica sinensis, chuanxiong rhizome, cyperus rotundus, and costus root. These components are used to invigorate blood circulation and regulate menstruation, and their synergistic effect is enhanced. The absence of these components will affect the sachet's effect on blood circulation and meridian regulation, thus failing to alleviate dysmenorrhea caused by cold stagnation and blood stasis.

[0067] Comparative Example 3

[0068] Angelica dahurica, cloves, mugwort, fennel, galangal, cinnamon, angelica sinensis, chuanxiong rhizome, cyperus rotundus, and costus root are ground into powder. The following weights of each component are then mixed evenly and placed in a sachet. The sachet is sealed to prevent leakage. Compared to Example 1, this herbal sachet lacks rose, osmanthus, and styrax, weakening its aromatic properties and affecting the patient's acceptance of the scent. This reduces their pleasure and may lead to resistance and other negative emotions, thus failing to alleviate dysmenorrhea caused by cold stagnation and blood stasis. Furthermore, the absence of styrax may reduce the likelihood of alleviating the severity of dysmenorrhea. The above comparative examples show that only by combining the 13 aromatic Chinese herbs of this invention can dysmenorrhea caused by cold stagnation and blood stasis be effectively relieved.

[0069] Furthermore, the 13 traditional Chinese herbs mentioned above in this invention were selected based on the principles of being aromatic, naturally beneficial, and free of toxic side effects. Throughout the intervention, all participants were thoroughly questioned about any potential adverse reactions they might experience via questionnaires or verbal reports. No adverse reactions were reported until the end of the intervention, indicating that the 13 aromatic traditional Chinese herbal medicines of this invention have no significant toxic side effects.

[0070] Obviously, those skilled in the art can make various modifications and variations to this invention without departing from its spirit and scope. Therefore, if these modifications and variations fall within the scope of the claims of this invention and their equivalents, this invention also intends to include these modifications and variations.

Claims

1. The application of an aromatic herbal composition in the preparation of an aromatherapy product for relieving dysmenorrhea caused by cold stagnation and blood stasis, characterized in that, The aromatic herbal composition comprises the following components in parts by weight: 3-7 parts Angelica dahurica, 4-6 parts cloves, 3-7 parts Artemisia argyi, 4-6 parts fennel, 3-7 parts Kaempferia galanga, 8-12 parts cinnamon, 8-12 parts Angelica sinensis, 8-12 parts Ligusticum chuanxiong, 8-12 parts Cyperus rotundus, 8-12 parts Aucklandia lappa, 13-17 parts Rosa rugosa, 14-16 parts Osmanthus fragrans, and 0.05-0.15 parts Styrax benzoin. The preparation method of the aromatic herbal composition is to grind Angelica dahurica, cloves, Artemisia argyi, fennel, Kaempferia galanga, cinnamon, Angelica sinensis, Ligusticum chuanxiong, Cyperus rotundus, Aucklandia lappa, Rosa rugosa, Osmanthus fragrans, and Styrax benzoin into powder, and then weigh and mix the corresponding parts by weight of the herbal powder.

2. The application according to claim 1, characterized in that, The aromatic herbal composition comprises the following components in parts by weight: 4-6 parts Angelica dahurica, 4-6 parts clove, 4-6 parts Artemisia argyi, 4-6 parts fennel, 4-6 parts Kaempferia galanga, 9-11 parts cinnamon, 9-11 parts Angelica sinensis, 9-11 parts Ligusticum chuanxiong, 9-11 parts Cyperus rotundus, 9-11 parts Aucklandia lappa, 14-16 parts rose, 14-16 parts Osmanthus fragrans, and 0.08-0.12 parts Styrax benzoin.

3. The application according to claim 1, characterized in that, The aromatic herbal composition comprises the following components in parts by weight: 5-6 parts Angelica dahurica, 5-6 parts clove, 5-6 parts Artemisia argyi, 5-6 parts fennel, 5-6 parts Kaempferia galanga, 10-11 parts cinnamon, 10-11 parts Angelica sinensis, 10-11 parts Ligusticum chuanxiong, 10-11 parts Cyperus rotundus, 10-11 parts Aucklandia lappa, 15-16 parts rose, 15-16 parts Osmanthus fragrans, and 0.1-0.12 parts Styrax benzoin.

4. The application according to claim 1, characterized in that, The aromatic herbal composition comprises the following components in parts by weight: 5-6 parts Angelica dahurica, 5-6 parts clove, 5-6 parts Artemisia argyi, 5-6 parts fennel, 5-6 parts Kaempferia galanga, 10-11 parts cinnamon, 10-11 parts Angelica sinensis, 10-11 parts Ligusticum chuanxiong, 10-11 parts Cyperus rotundus, 10-11 parts Aucklandia lappa, 15 parts rose, 15 parts Osmanthus fragrans, and 0.1 parts Styrax benzoin.

5. The application according to claim 1, characterized in that, The aromatic herbal composition comprises the following components in parts by weight: 5-6 parts Angelica dahurica, 5-6 parts clove, 5-6 parts Artemisia argyi, 5-6 parts fennel, 5-6 parts Kaempferia galanga, 10 parts cinnamon, 10 parts Angelica sinensis, 10 parts Ligusticum chuanxiong, 10 parts Cyperus rotundus, 10 parts Aucklandia lappa, 15 parts rose, 15 parts Osmanthus fragrans, and 0.1 parts Styrax benzoin.

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