Processing equipment for pharmaceutical preparation production

By incorporating components such as airbag rings and scrapers into pharmaceutical formulation production equipment, the degree of expansion and material distribution are controlled, thus solving the problem of uneven extrusion caused by the gravity of the roller and achieving uniform extrusion and efficient granulation of materials.

CN117160359BActive Publication Date: 2026-01-30GUORUI YINUO DRUG SAFETY EVALUATION RES CO LTD IN XIXIAN NEW AREA
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Patent Information

Application Number
CN202311335135.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-10-16
Publication Date
2026-01-30
Estimated Expiration
2043-10-16

AI Technical Summary

Technical Problem

In existing pharmaceutical preparation production equipment, the pressure exerted on the material by the lower side of the sieve grid is greater due to the weight of the roller itself, resulting in uneven pressure on the left and right sides of the sieve grid, which affects the uniformity of the drug particles.

Method used

By incorporating components such as airbag rings, sealing rings, air inlet pipes, and arc-shaped guide rails into the equipment, the expansion degree of the airbag rings is controlled, ensuring consistent extrusion pressure on the material at different locations. The scraper and discharge hopper ensure uniform material distribution and extrusion, while the spring rod and scraper remove adhering material, thereby improving granulation efficiency.

Benefits of technology

It achieves uniform extrusion and distribution of materials on the sieve plate, avoids material accumulation in the same position, improves granulation efficiency and uniformity, and reduces material waste.

✦ Generated by Eureka AI based on patent content.

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Abstract

This invention relates to the field of pharmaceutical processing, and more particularly to a processing equipment for pharmaceutical preparation production. Technical problem: The roller exerts greater compressive force on the material under its own weight on the lower side of the sieve, resulting in a different compressive force compared to the material on the left and right sides of the sieve. The technical solution of this invention is: a processing equipment for pharmaceutical preparation production, comprising a base, a fixed cylinder, and a feed cylinder; the fixed cylinder is fixedly connected to the base; the fixed cylinder connects to two feed cylinders; it also includes a motor, a rotating frame, etc.; the motor is fixedly connected to the rear side of the fixed cylinder; the output shaft of the motor is fixedly connected to the rotating frame, and the rotating frame is rotatably connected to the fixed cylinder. This invention uses a scraper to scrape the surface of a rotating airbag ring, scraping off the material adhering to the surface of the airbag ring. Furthermore, as the scraper reciprocates with the airbag ring, it vibrates under the elastic force of spring rod II, thereby shaking the material adhering to the scraper onto the sieve plate.
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Description

Technical Field

[0001] This invention relates to the field of pharmaceutical processing, and more particularly to a processing equipment for pharmaceutical preparation production. Background Technology

[0002] Existing Chinese patent CN215139612U discloses a swing-type granulation device for pharmaceutical formulation processing. It is equipped with a stirring and bonding mechanism at the feed inlet, which completes the bonding of powdered materials in the inner cavity of the feed inlet without the need for other devices, thus optimizing the granulation process and saving production time. In addition, a hot air blower is set in the storage cavity to dry the materials. The device has a high degree of integration and can complete the entire process of granulating and drying powdered materials in the same device.

[0003] However, due to the weight of the roller itself, the roller exerts a greater squeezing force on the material on the lower side of the sieve due to its own weight. This results in a different squeezing force on the material compared to the left and right sides of the sieve, causing inconsistent compactness of the material after it is squeezed out of the sieve and affecting the uniformity of the drug particles. Summary of the Invention

[0004] In order to overcome the disadvantage that the pressure exerted on the material by the roller on the lower side of the screen is greater due to its own weight, resulting in a different pressure on the material compared to the pressure exerted on the left and right sides of the screen, the present invention provides a processing device for pharmaceutical preparation production.

[0005] The technical solution of this invention is as follows: a processing equipment for pharmaceutical preparation production, comprising a base, a fixed cylinder, and a feeding cylinder; the fixed cylinder is fixedly connected to the base; a discharge port is provided on the lower side of the fixed cylinder; the fixed cylinder is connected to two feeding cylinders distributed to the left and right; it also includes a motor, a rotating frame, a rotating shaft, an air bladder ring, a sieve plate, a fixed plate, a sealing ring, an air inlet pipe, an arc-shaped guide rail, and a moving block; a motor is fixedly connected to the rear side of the fixed cylinder; the output shaft of the motor is fixedly connected to the rotating frame, and the rotating frame is rotatably connected to the fixed cylinder, and the rotating frame is located inside the fixed cylinder, and the rotating shaft of the rotating frame is connected to the shaft of the fixed cylinder. The lines coincide; a rotating shaft is fixedly connected to the lower side of the rotating frame; an airbag ring is rotatably connected to the rotating shaft, and the rotating shaft communicates with the airbag ring; a fixed plate is fixedly connected to the front and rear sides of the fixed cylinder; an arc-shaped guide rail is fixedly connected to each fixed plate; a moving block is slidably connected to each arc-shaped guide rail; two moving blocks are jointly fixedly connected to a sieve plate for screening out the drug particles, and the sieve plate is in contact with the airbag ring; an annular groove is opened on the front and rear sides of the fixed cylinder; a sealing ring is slidably connected to each annular groove; an air inlet pipe is fixedly connected to each sealing ring, and the air inlet pipe communicates with the rotating shaft.

[0006] More preferably, it also includes a spring rod I and a round rod; two rod groups are fixedly connected to the lower side of the rotating shaft, each rod group consists of two spring rods I distributed front and back, and a round rod is fixedly connected to the telescopic end of each of the two spring rods I located in the same rod group, and the round rod is in contact with the inner side of the airbag ring.

[0007] More preferably, the two rod groups are arranged at relative angles.

[0008] More preferably, it also includes pressure balls; several pressure balls are fixed to the underside of each round rod.

[0009] More preferably, it also includes scrapers; one scraper is fixed to each of the left and right sides of the sieve plate, and the scraper contacts the inside of the fixed cylinder.

[0010] More preferably, it also includes a discharge hopper; two discharge hoppers are fixedly connected to the inner side of the fixed cylinder, and the discharge hoppers are flat and connected to the feed cylinder.

[0011] More preferably, the scraper blade is inclined on its lower side.

[0012] More preferably, it also includes a spring rod II and a scraper; two spring rods II are fixedly connected to the lower side of the rotating frame, distributed on the left and right; and a scraper is fixedly connected to the telescopic end of each spring rod II.

[0013] More preferably, it also includes an arc-shaped plate and a limiting ball; an arc-shaped plate is fixedly connected to the inner front side and the inner rear side of the fixed cylinder; and several spaced limiting balls are fixedly connected to the opposing sides of the two arc-shaped plates.

[0014] More preferably, the scraper is designed in an arc shape.

[0015] Beneficial effects: This invention uses a rotating shaft to cause the air inlet pipe to slide within the annular groove as the airbag ring moves. When the airbag ring moves to the lower side of the sieve plate, the external air pump is controlled to reduce the air intake through the air inlet pipe, resulting in less gas inside the airbag ring and thus less expansion of the airbag ring, leading to less pressure on the material. Conversely, when the air inlet pipe passes the left and right sides of the sieve plate, the external air pump is controlled to increase the air intake through the air inlet pipe, resulting in more gas inside the airbag ring and thus greater expansion of the airbag ring, leading to greater pressure on the material. This ensures that the pressure exerted by the airbag ring on the lower side of the sieve plate and on the left and right sides of the sieve plate is consistent, resulting in uniform pressure on the material on the sieve plate.

[0016] This invention utilizes the guiding effect of a flat discharge hopper to ensure that the material from the feed cylinder falls evenly onto the screen plate. Simultaneously, the arc-shaped guide rail controls the moving block to rotate the screen plate and scraper, thereby changing the position where the material falls onto the screen plate. This results in a more uniform distribution of the material on the screen plate, preventing material from falling to the same position and causing the air bladder ring to fail to expel all the material accumulated in the same position, which leads to low material extrusion efficiency.

[0017] This invention uses a scraper to scrape the surface of a rotating airbag ring, removing the material adhering to the surface of the airbag ring. As the scraper swings back and forth with the airbag ring, it compresses the spring rod II under the limiting action of the limiting ball. As a result, the scraper vibrates back and forth under the elastic force of the spring rod II, thereby shaking the material adhering to the scraper onto the screen plate. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the structure of the pharmaceutical preparation manufacturing equipment disclosed in this invention;

[0019] Figure 2 This is a partial structural schematic diagram of the processing equipment for pharmaceutical preparation production disclosed in this invention;

[0020] Figure 3 This is a partial structural diagram of the combination of the fixed cylinder, motor, rotating frame, rotating shaft, airbag ring, sieve plate, fixed plate, sealing ring and arc plate disclosed in the processing equipment for pharmaceutical preparation production of the present invention;

[0021] Figure 4 This is a partial structural diagram of the combination of the rotating frame, rotating shaft, airbag ring, sieve plate, fixing plate and air inlet pipe of the processing equipment for pharmaceutical preparation production disclosed in this invention.

[0022] Figure 5 This is a partial structural diagram of the combination of airbag ring, sieve plate, fixed plate, arc guide rail, moving block and scraper disclosed in the processing equipment for pharmaceutical preparation production of the present invention;

[0023] Figure 6 This is a partial structural diagram of the combination of the rotating shaft, airbag ring, sieve plate, spring rod I, round rod, pressure ball, spring rod II, scraper, arc plate, and limiting ball disclosed in the processing equipment for pharmaceutical preparation production of the present invention.

[0024] Figure 7 This is a partial structural diagram of the combination of a fixed cylinder, sieve plate, scraper, and discharge hopper disclosed in the processing equipment for pharmaceutical preparation production of the present invention.

[0025] The markings in the diagram are as follows: 1-base, 2-fixed cylinder, 3-feed cylinder, 201-motor, 202-rotating frame, 203-rotating shaft, 204-airbag ring, 205-sieve plate, 206-fixed plate, 207-sealing ring, 208-air inlet pipe, 209-arc guide rail, 2010-moving block, 2011-spring rod I, 2012-round rod, 2013-pressure ball, 2014-spring rod II, 2015-scraper, 2016-arc plate, 2017-limiting ball, 2018-scraper blade, 2019-discharge hopper, 2a-discharge port, 2b-annular groove. Detailed Implementation

[0026] The present invention will be further described below with reference to the embodiments shown in the accompanying drawings.

[0027] Example 1

[0028] A pharmaceutical preparation manufacturing processing equipment, such as Figure 1-7 As shown, it includes a base 1, a fixed cylinder 2, and a feed cylinder 3; the fixed cylinder 2 is bolted to the base 1; the fixed cylinder 2 has a discharge port 2a on its lower side; the fixed cylinder 2 is connected to two feed cylinders 3 distributed on the left and right sides;

[0029] It also includes a motor 201, a rotating frame 202, a rotating shaft 203, an airbag ring 204, a sieve plate 205, a fixed plate 206, a sealing ring 207, an air inlet pipe 208, an arc-shaped guide rail 209, and a moving block 2010; the motor 201 is bolted to the rear side of the fixed cylinder 2; the output shaft of the motor 201 is fixedly connected to the rotating frame 202, and the rotating frame 202 is rotatably connected to the fixed cylinder 2, and the rotating frame 202 is located inside the fixed cylinder 2, and the rotation shaft of the rotating frame 202 coincides with the axis of the fixed cylinder 2; the rotating shaft 203 is fixedly connected to the lower side of the rotating frame 202; the airbag ring 204 is rotatably connected to the rotating shaft 203, and the airbag ring 204 is rotatably connected to the rotating shaft 203. The airbag ring 204 is connected; a fixed plate 206 is fixedly connected to the front and rear sides of the fixed cylinder 2; each fixed plate 206 is bolted to an arc-shaped guide rail 209; each arc-shaped guide rail 209 is slidably connected to a moving block 2010; the two moving blocks 2010 are jointly fixedly connected to a sieve plate 205 for screening out the drug particles, and the sieve plate 205 is in contact with the airbag ring 204; an annular groove 2b is opened on the front and rear sides of the fixed cylinder 2; a sealing ring 207 is slidably connected in each annular groove 2b; each sealing ring 207 is fixedly connected to an air inlet pipe 208, and the air inlet pipe 208 is connected to the rotating shaft 203.

[0030] It also includes a spring rod I 2011 and a round rod 2012; two rod groups are fixedly connected to the lower side of the rotating shaft 203, each rod group consists of two spring rods I 2011 distributed front and back, and a round rod 2012 is fixedly connected to the telescopic end of each of the two spring rods I 2011 in the same rod group, and the round rod 2012 is in contact with the inner side of the airbag ring 204.

[0031] The two rods are arranged at relative inclinations, thereby increasing the area of ​​the round rod 2012 pressing open the inner side of the airbag ring 204, thus increasing the contact area between the airbag ring 204 and the sieve plate 205.

[0032] It also includes pressure balls 2013; several pressure balls 2013 are fixed to the underside of each round rod 2012.

[0033] It also includes a scraper 2018; a scraper 2018 is fixedly connected to the left and right sides of the sieve plate 205, and the scraper 2018 is in contact with the inner side of the fixed cylinder 2.

[0034] It also includes a discharge hopper 2019; two discharge hoppers 2019 are fixedly connected to the inner side of the fixed cylinder 2, and the discharge hoppers 2019 are flat and connected to the feed cylinder 3.

[0035] The scraper blade 2018 is inclined at the bottom, so as to scrape off the material adhering to the inside of the fixed cylinder 2 and guide the scraped material downward, so as to prevent the scraped material from accumulating on the scraper blade 2018.

[0036] The working steps of the above embodiment are as follows: First, connect the external air pump to the air inlet pipe 208. After the material enters the fixed cylinder 2 from the feed cylinder 3, the material falls onto the left and right sides of the screen plate 205. At this time, control the external air pump to start and inflate the airbag ring 204, so that the airbag ring 204 is cylindrical and tightly attached to the upper side of the screen plate 205. Figure 3 As shown, the control motor 201 is then started, and the output shaft of the motor 201 drives the rotating frame 202, the rotating shaft 203, and the airbag ring 204 to rotate. Since the rotating shaft of the rotating frame 202 coincides with the axis of the fixed cylinder 2, the airbag ring 204 swings back and forth around the axis of the fixed cylinder 2. As a result, the airbag ring 204 rolls on the screen plate 205 under the action of friction with the screen plate 205. The airbag ring 204 rotates relative to the rotating shaft 203, thereby the airbag ring 204 rolls the material on the screen plate 205, causing the material to be squeezed out from the mesh on the screen plate 205 as granular medicine particles. Subsequently, the medicine particles fall out from the discharge port 2a.

[0037] During the rolling process of the airbag ring 204 on the material on the screen plate 205, due to the gravity of the airbag ring 204 itself, the squeezing force of the airbag ring 204 on the material on the lower side of the screen plate 205 is different from that on the left and right sides of the screen plate 205. The squeezing force of the airbag ring 204 on the material on the lower side of the screen plate 205 is greater than that on the left and right sides of the screen plate 205, resulting in uneven squeezing of the material on the screen plate 205. At this time, when the rotating shaft 203 moves, it causes the air inlet pipe 208 to drive the sealing ring 207 to slide in the annular groove 2b. When the airbag ring 204 moves to the lower side of the screen plate 205, the external air pump is controlled to reduce the pressure on the air inlet pipe 208. The reduced air intake of 8 reduces the gas volume within the airbag ring 204, resulting in a smaller expansion of the airbag ring 204 and thus a smaller compressive force on the material. Meanwhile, as the air intake pipe 208 passes through the left and right sides of the sieve plate 205, the external air pump increases the air intake volume, increasing the gas volume within the airbag ring 204. This leads to a greater expansion of the airbag ring 204 and a greater compressive force on the material. Consequently, the compressive force exerted by the airbag ring 204 on the lower side of the sieve plate 205 and on the left and right sides of the sieve plate 205 becomes consistent, ensuring that the material experiences uniform compressive force on the sieve plate 205.

[0038] When the airbag ring 204 rolls the material on the sieve plate 205, the inclined spring rod I 2011 and round rod 2012 squeeze the inner lower side of the airbag ring 204, thereby causing the inner lower side of the airbag ring 204 to undergo adaptive deformation and increase the contact area with the sieve plate 205. This allows the airbag ring 204 to roll more material, improving the granulation efficiency of the material. Furthermore, the pressure ball 2013 squeezes the airbag ring 204, causing it to undergo adaptive deformation and be squeezed into the mesh of the sieve plate 205, thereby expelling the material adhering to the mesh of the sieve plate 205.

[0039] After the material falls from the feed cylinder 3 into the fixed cylinder 2, it tends to accumulate on the screen plate 205 in a clump, affecting the rolling efficiency of the airbag ring 204. At this time, the flat discharge hopper 2019 guides the material from the feed cylinder 3 to fall evenly onto the screen plate 205. At the same time, the arc-shaped guide rail 209 controls the moving block 2010 to drive the screen plate 205 and scraper 2018 to rotate, thereby changing the position of the material falling on the screen plate 205, and thus making the material evenly distributed on the screen plate 205. To ensure uniformity and prevent material from falling to the same position on the screen plate 205, the airbag ring 204 cannot squeeze out all the material accumulated at the same position on the screen plate 205, resulting in low material extrusion efficiency. At the same time, since the material contains adhesive liquid, some material particles squeezed out from the lower side of the screen plate 205 will adhere to the inner side of the fixed cylinder 2. At this time, the screen plate 205 drives the scraper 2018 to rotate, so that the scraper 2018 scrapes the material adhering to the inner side of the fixed cylinder 2 down to the discharge port 2a.

[0040] Example 2

[0041] Based on Example 1, such as Figure 3 and Figure 6 As shown, it also includes a spring rod II 2014 and a scraper 2015; two spring rods II 2014 distributed on the left and right are fixedly connected to the lower side of the rotating frame 202; each spring rod II 2014 has a scraper 2015 fixedly connected to its telescopic end.

[0042] It also includes an arc plate 2016 and a limiting ball 2017; an arc plate 2016 is fixedly connected to the inner front side and the inner rear side of the fixed cylinder 2; several limiting balls 2017 are fixedly connected to the opposing sides of the two arc plates 2016 at intervals.

[0043] The scraper 2015 is arc-shaped, which guides the scraped material downward back into the fixed cylinder 2, preventing it from accumulating on the scraper 2015.

[0044] The working steps of the above embodiment are as follows: When the material on the airbag ring 204 and the screen plate 205 is squeezed, the surface of the airbag ring 204 will be covered with material, which will cause some material to be unable to be squeezed out, resulting in waste. At this time, the scraper 2015 scrapes the surface of the rotating airbag ring 204 to scrape off the material on the surface of the airbag ring 204. When the scraper 2015 swings back and forth with the airbag ring 204, the scraper 2015 compresses the spring rod II 2014 under the limiting action of the limiting ball 2017. As a result, the scraper 2015 vibrates back and forth under the elastic force of the spring rod II 2014, thereby shaking the material on the scraper 2015 onto the screen plate 205.

[0045] The above description is merely an embodiment of the present invention and is not intended to limit the present invention. All equivalent substitutions made within the principles of the present invention should be included within the scope of protection of the present invention. Contents not described in detail in this invention belong to existing technology known to those skilled in the art.

Claims

1. A processing equipment for pharmaceutical preparation production, comprising a base (1); the base (1) is fixedly connected with a fixed cylinder (2); the lower side of the fixed cylinder (2) is provided with a discharge port (2a); the fixed cylinder (2) is communicated with two left and right distributed feeding cylinders (3); characterized in that: The motor (201) is further included; the motor (201) is fixedly connected to the rear side of the fixed cylinder (2); the output shaft of the motor (201) is fixedly connected with a rotating frame (202), and the rotating frame (202) is rotationally connected with the fixed cylinder (2), and the rotating frame (202) is located inside the fixed cylinder (2), and the rotating shaft of the rotating frame (202) coincides with the axis of the fixed cylinder (2); the lower side of the rotating frame (202) is fixedly connected with a rotating shaft (203); the rotating shaft (203) is rotationally connected with an air bag ring (204), and the rotating shaft (203) communicates with the air bag ring (204); one fixed plate (206) is fixedly connected to the inner front side and the inner rear side of the fixed cylinder (2) respectively; each fixed plate (206) is fixedly connected with an arc-shaped guide rail (209); each arc-shaped guide rail (209) is slidingly connected with a moving block (2010); two moving blocks (2010) are fixedly connected with a sieve plate (205) for sieving medicine particles, and the sieve plate (205) is in contact with the air bag ring (204); an annular groove (2b) is formed in the front side and the rear side of the fixed cylinder (2) respectively; each annular groove (2b) is slidingly connected with a sealing ring (207); each sealing ring (207) is fixedly connected with an air inlet pipe (208), and the air inlet pipe (208) communicates with the rotating shaft (203).

2. The processing apparatus for pharmaceutical preparation production according to claim 1, characterized in that: The spring rod I (2011) and the round rod (2012) are further included; the lower side of the rotating shaft (203) is fixedly connected with two rod groups distributed left and right, each rod group is composed of two spring rod Is (2011) distributed front and back, the telescopic ends of the two spring rod Is (2011) in the same rod group are fixedly connected with a round rod (2012), and the round rod (2012) is in contact with the inner side of the air bag ring (204).

3. The processing apparatus for pharmaceutical preparation production according to claim 2, characterized in that: The two rod groups are oppositely inclined.

4. The processing apparatus for pharmaceutical preparation production according to claim 2, characterized in that: The pressing ball (2013) is further included; the lower side of each round rod (2012) is fixedly connected with a plurality of pressing balls (2013).

5. The processing apparatus for pharmaceutical preparation production according to claim 1, characterized in that: The scraping piece (2018) is further included; one scraping piece (2018) is fixedly connected to the left side and the right side of the sieve plate (205), and the scraping piece (2018) is in contact with the inner side of the fixed cylinder (2).

6. A processing apparatus for pharmaceutical preparations according to any one of claims 1 to 5, characterized in that: The discharge hopper (2019) is further included; two discharge hoppers (2019) distributed left and right are fixedly connected to the inner side of the fixed cylinder (2), and the discharge hoppers (2019) are flat, and the discharge hoppers (2019) communicate with the inlet cylinder (3).

7. The processing apparatus for pharmaceutical preparation production according to claim 5, characterized in that: The lower side of the scraping piece (2018) is inclined.

8. The processing apparatus for pharmaceutical preparation production according to claim 1, characterized in that: The spring rod II (2014) and the scraping plate (2015) are further included; two spring rod IIs (2014) distributed left and right are fixedly connected to the lower side of the rotating frame (202); the telescopic ends of each spring rod II (2014) are fixedly connected with a scraping plate (2015).

9. The processing apparatus for pharmaceutical preparation production according to claim 8, characterized in that: The arc-shaped plate (2016) and the limiting ball (2017) are further included; one arc-shaped plate (2016) is fixedly connected to the inner front side and the inner rear side of the fixed cylinder (2); a plurality of limiting balls (2017) distributed at intervals are fixedly connected to the opposite sides of the two arc-shaped plates (2016).

10. The processing apparatus for pharmaceutical preparation production according to claim 8, characterized in that: The scraping plate (2015) is arc-shaped.

Citation Information

Patent Citations

  • Swing type granulating device for medicinal preparation processing

    CN215139612U

  • Continuous flow granulation drying device

    CN218077755U

  • Modified plastic extruder

    CN218111663U