Valve clamping devices and valve repair systems

Abstract

In the field of medical device technology, a valve clamping device and a valve repair system are provided. The valve clamping device includes a main body and a clamping body, the clamping body including a clamping member mounted on the main body. The main body includes a transmission assembly, which includes a first link and a second link. The distal end of the first link and the proximal end of the second link are provided with a transmission structure, which transmits axial movement between the first and second links. The clamping member is hinged to the distal end of the second link, and the axial movement of the second link drives the opening and closing movement of the clamping member, changing the angle between the clamping member and the main body. This segmented transmission structure isolates the radial movement trend from the first segment to the second segment of the main body. Thus, the second segment drives the opening and closing movement of the clamping member, making the movement of the clamping member tend to be continuous and stable. During operation, the valve clamping device has a more stable state, which is beneficial for the operator to control the clamping member and reduces the difficulty of operation.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and more particularly to a valve clamping device and a valve repair system. Background Technology

[0002] Medical devices are playing an increasingly important role in disease diagnosis and treatment. Transcatheter interventional therapy, which can achieve better treatment results with smaller incisions and is more conducive to postoperative recovery, has thus experienced rapid development. Operators often rely on image guidance when delivering and manipulating medical devices via catheters, but they still face challenges due to the complex environment inside the patient's body, necessitating continuous improvement of medical devices and their performance. Summary of the Invention

[0003] This application provides a valve clamping device and a valve repair system with better performance to improve the effectiveness of transcatheter interventional therapy.

[0004] In a first aspect, this application provides a valve clamping device, including a main body and a clamping body, the clamping body being mounted on the main body; the main body includes a transmission assembly, the transmission assembly including a first link and a second link, the distal end of the first link and the proximal end of the second link being provided with a transmission structure, the transmission structure transmitting axial movement between the first link and the second link; the clamping body includes a clamping member, the clamping member being hinged to the distal end of the second link, the axial movement of the second link driving the opening and closing movement of the clamping member, changing the included angle between the clamping member and the main body.

[0005] In one implementation, the driving force of the valve clamping device acts radially on the first link, and the transmission structure transmits axial motion while preventing the radial motion tendency from being transmitted to the second link.

[0006] In one implementation, the transmission structure includes a first limiting structure and a second limiting structure; the first limiting structure is disposed at the distal end of the first connecting rod, and the second limiting structure is disposed at the proximal end of the second connecting rod, and the first limiting structure and the second limiting structure abut against each other axially when the first connecting rod or the second connecting rod moves axially.

[0007] In one implementation, the axial contact between the first limiting structure and the second limiting structure restricts the relative movement of the first link and the second link in one axial direction, or the axial contact between the first limiting structure and the second limiting structure restricts the relative movement of the first link and the second link in two axial directions.

[0008] In one implementation, the second limiting structure has a concave side surface, and the first limiting structure has an extension extending inward toward the first connecting rod, the extension being located within a groove on the concave side surface.

[0009] In one implementation, the first limiting structure includes a limiting member disposed at the distal end of the first link, the limiting member having a chamber having a distal opening, the proximal end of the second link passing through the distal opening, a second limiting structure at the proximal end of the second link being accommodated in the chamber, and the maximum size of the second limiting structure being larger than the size of the distal opening.

[0010] In one implementation, the second limiting structure includes a limiting member disposed at the proximal end of the second link, the limiting member having a chamber having an opening toward the proximal end, the distal end of the first link passing through the opening toward the proximal end, the first limiting structure at the distal end of the first link being accommodated in the chamber, and the maximum size of the first limiting structure being larger than the size of the opening toward the proximal end.

[0011] In one implementation, the second limiting structure located in the cavity of the limiting member is spherical or ellipsoidal; or, the first limiting structure located in the cavity of the limiting member is spherical or ellipsoidal.

[0012] In one implementation, the first limiting structure includes a limiting member disposed at the distal end of the first link, the chamber of the limiting member further having a proximal opening, the distal end of the first link passing through the proximal opening and abutting against the second limiting structure at the proximal end of the second link during axial movement toward the distal end.

[0013] In one implementation, the second limiting structure includes a limiting member disposed at the proximal end of the second link, the chamber of the limiting member further having a distal opening, the proximal end of the second link passing through the distal opening and abutting against the first limiting structure at the proximal end of the first link during distal axial movement within the chamber.

[0014] In one implementation, the first limiting structure is integrally formed with the first connecting rod, and the second limiting structure is integrally formed with the second connecting rod; or, the first limiting structure is integrally formed with the first connecting rod, and the second limiting structure is fixedly connected to the second connecting rod; or, the first limiting structure is fixedly connected to the first connecting rod, and the second limiting structure is integrally formed with the second connecting rod; or, the first limiting structure is fixedly connected to the first connecting rod, and the second limiting structure is fixedly connected to the second connecting rod.

[0015] In one implementation, at least one of the abutting surfaces in the transmission assembly has a raised structure.

[0016] In one implementation, the first link has an internal space with a non-circular cross-section.

[0017] In one implementation, the cross-section of the internal space is elliptical, rectangular, triangular, or racetrack-shaped.

[0018] In one implementation, the main body further includes: an attachment, a first connecting rod disposed within the attachment, and the inner wall of the attachment having an internal thread, the outer wall of the first connecting rod having an external thread, the helicity of the internal thread and the external thread being matched.

[0019] In one implementation, the clamping body further includes a gripping element disposed between the main body and the clamping element.

[0020] In a second aspect, a valve repair system is provided, including any of the valve clamping devices of the first aspect above and a delivery system, the delivery system being used to deliver and control the valve clamping device.

[0021] In one implementation, the delivery system includes a catheter and a delivery device, the delivery device including a control mechanism and a delivery rod, the proximal end of the delivery rod being connected to the control mechanism, the distal end of the delivery rod passing through the catheter and acting radially on the transmission assembly of the valve clamping device, and the distal end of the delivery rod having a non-circular cross-section.

[0022] In one implementation, the contact surface of the delivery rod and the second link of the transmission assembly of the valve clamping device has a raised structure.

[0023] The valve clamping device and valve repair system described above adopt a segmented transmission structure, which isolates the radial movement trend from the first segment to the second segment of the main body. In this way, the second segment drives the opening and closing movement of the clamping component, making the movement of the clamping component tend to be continuous and stable. During operation, the valve clamping device has a more stable state, which is conducive to the operator's control of the clamping component and reduces the difficulty of operation. Attached Figure Description

[0024] The following is a brief introduction to the accompanying drawings used in the description of the embodiments of this application:

[0025] Figure 1 This is a schematic diagram of a treatment application scenario used in the embodiments of this application;

[0026] Figure 2 This is a schematic diagram of the structure of a valve repair system provided in an embodiment of this application;

[0027] Figure 3 This is a schematic diagram of the distal enlarged valve clamping device of a valve repair system provided in an embodiment of this application;

[0028] Figure 4 This is a plan view of a valve clamping device provided in the embodiment of this application in the closed state;

[0029] Figure 5 This is a plan view of a valve clamping device provided in an embodiment of this application in an open state;

[0030] Figure 6 This is a plan view of a valve clamping device provided in an embodiment of this application in another open state;

[0031] Figure 7This is a plan view of a valve clamping device provided in an embodiment of this application in an inverted state;

[0032] Figures 8-14 This is a schematic diagram of a valve clamping device provided in an embodiment of this application during operation;

[0033] Figure 15 yes Figure 4 A cross-sectional view along the AA direction of one embodiment of the valve clamping device shown.

[0034] Figure 16 yes Figure 5 or Figure 6 A cross-sectional view along the AA direction of one embodiment of the valve clamping device shown.

[0035] Figure 17 yes Figure 7 A cross-sectional view along the AA direction of one embodiment of the valve clamping device shown.

[0036] Figure 18 This is a plan view of a transmission assembly provided in an embodiment of this application;

[0037] Figure 19 This is a plan view of another transmission component provided in an embodiment of this application;

[0038] Figure 20 This is a plan view of yet another transmission component provided in an embodiment of this application;

[0039] Figure 21 This is a plan view of yet another transmission component provided in an embodiment of this application;

[0040] Figure 22 This is a plan view of yet another transmission component provided in an embodiment of this application;

[0041] Figure 23 This is a plan view of a limiting structure provided in an embodiment of this application;

[0042] Figure 24 This is a plan view of another limiting structure provided in the embodiments of this application;

[0043] Figure 25 This is a cross-sectional view of a valve clamping device provided in an embodiment of this application when the delivery rod is inserted;

[0044] Figure 26 This is a cross-sectional view of another valve clamping device provided in an embodiment of this application;

[0045] Figure 27 This is a cross-sectional view of another valve clamping device provided in the embodiments of this application;

[0046] Figure 28 This is a plan view of a protruding structure provided in an embodiment of this application;

[0047] Figure 29 This is a plan view of another protruding structure provided in an embodiment of this application;

[0048] Figure 30 This is a plan view of yet another protruding structure provided in the embodiments of this application;

[0049] Figure 31 This is a three-dimensional structural schematic diagram of a valve clamping device provided in an embodiment of this application;

[0050] Figure 32 This is a three-dimensional structural diagram of a clamping component provided in an embodiment of this application;

[0051] Figure 33 yes Figure 32 A plan view of the clamping assembly shown;

[0052] Figure 34 This is a three-dimensional structural schematic diagram of another clamping component provided in an embodiment of this application;

[0053] Figure 35 This is a side view of yet another clamping component provided in an embodiment of this application;

[0054] Figure 36 yes Figure 35 Another side view of the clamping component shown;

[0055] Figure 37 This is a three-dimensional structural diagram of another valve clamping device connected to a clutch device according to an embodiment of this application;

[0056] Figure 38 This is a three-dimensional structural diagram of a support member provided in an embodiment of this application;

[0057] Figure 39 This is a three-dimensional structural schematic diagram of another support member provided in an embodiment of this application;

[0058] Figure 40 This is a cross-sectional view of a support member provided in an embodiment of this application;

[0059] Figure 41 This is a plan view of yet another support member provided in an embodiment of this application;

[0060] Figure 42 This is a three-dimensional structural diagram of a capture device provided in an embodiment of this application;

[0061] Figure 43 yes Figure 42A side view of the capture device shown;

[0062] Figure 44 This is a three-dimensional structural schematic diagram of another capture device provided in an embodiment of this application;

[0063] Figure 45 yes Figure 44 A side view of the capture device shown;

[0064] Figure 46 This is a three-dimensional structural schematic diagram of another capture device provided in the embodiments of this application;

[0065] Figure 47 This is a three-dimensional structural schematic diagram of another valve clamping device provided in the embodiments of this application;

[0066] Figure 48 yes Figure 47 The diagram shown is a three-dimensional structural view of the support component with the capture device installed from another perspective.

[0067] Figure 49 This is a three-dimensional structural schematic diagram of another support member provided in the embodiments of this application;

[0068] Figure 50 This is a side view of another support member equipped with a capture device provided in an embodiment of this application;

[0069] Figure 51 This is a three-dimensional structural diagram of a clutch device in its natural state, provided in an embodiment of this application.

[0070] Figure 52 This is a three-dimensional structural diagram of a clutch device under external force according to an embodiment of this application;

[0071] Figure 53 This is a side view of a clutch device provided in an embodiment of this application;

[0072] Figure 54 This is a three-dimensional structural diagram of a connection structure on a main body provided in an embodiment of this application;

[0073] Figure 55 This is a three-dimensional structural diagram of another connection structure on the main body provided in an embodiment of this application;

[0074] Figure 56 This is a three-dimensional structural schematic diagram of a clutch device connected with a valve clamping device provided in an embodiment of this application;

[0075] Figure 57 yes Figure 56 The image shows a side view of the clutch device connected to the valve clamping device;

[0076] Figure 58 This is a three-dimensional structural schematic diagram of another clutch device connected with a valve clamping device provided in the embodiments of this application. Detailed Implementation

[0077] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the specific implementation methods of this application will be described below with reference to the accompanying drawings. The accompanying drawings described below are merely some embodiments of this application. For those skilled in the art, other drawings and other implementation methods can be obtained based on these drawings without creative effort. Adjustments and improvements made without departing from the concept of this application are all within the protection scope of this application.

[0078] To keep the drawings concise, the figures in this application only schematically show the parts relevant to this application, and they do not represent the actual structure of the product. Furthermore, to make the drawings concise and easy to understand, some figures only schematically show parts of components with the same structure or function; in reality, there may be more or fewer components with the same structure or function.

[0079] In this application, unless otherwise expressly specified and limited, ordinal numbers, such as "first," "second," etc., are used only to distinguish and describe related objects, and should not be construed as indicating or implying the relative importance or order between related objects; furthermore, they do not represent the number of related objects. "And / or" is used to describe the relationship between related objects, which includes any relationship between the related objects; for example, "a and / or b" includes: "a alone," "b alone," or "a and b." The terms "installation" and "connection" should be interpreted broadly; for example, "installation" can be direct installation or installation via other components; "connection" can be direct connection or connection via other components. The term "relative arrangement" includes parallel relative or relative at a certain angle, the angle of which is not limited and is determined according to the number of objects in the relative arrangement.

[0080] In the embodiments shown in the accompanying drawings, the directional indications (such as up, down, left, right, front, and back) are relative rather than absolute when describing the structure and movement of the various components, and are not intended to limit the direction of the product during actual use.

[0081] In the embodiments of this application, "proximal end" refers to the end of the associated object closer to the operator; "distal end" refers to the end of the associated object farther from the operator. "Proximal end" and "distal end" are the position or orientation of the associated object (e.g., a component of a medical device) relative to the operator (e.g., a doctor) from the perspective of the operator using the device (e.g., a medical device). For example, "proximal end" refers to the end closer to the doctor during normal operation of the medical device, while "distal end" refers to the end farther from the doctor during normal operation of the medical device, that is, the end that first enters the patient's body.

[0082] Medical devices are playing an increasingly important role in disease diagnosis and treatment. Transcatheter interventional therapy, which can achieve therapeutic effects through smaller incisions and facilitates postoperative recovery, has therefore experienced rapid development. For example, please refer to... Figure 1 This is a schematic diagram of a therapeutic application scenario used in an embodiment of this application, illustrating the structure of the heart: the heart is a hollow muscular organ with four chambers, namely the left atrium (LA) 11, the right atrium (RA) 21, the left ventricle (LV) 12, and the right ventricle (RV) 22. Atrioventricular valves (hereinafter referred to as valves) are located between the atria and ventricles. During ventricular diastole, the valves open, allowing blood to flow from the atria into the ventricles; during ventricular systole, the valves close, preventing blood from flowing back from the ventricles into the atria. The valve between the left atrium 11 and the left ventricle 12 is the mitral valve (MV) 13, and the valve between the right atrium 21 and the right ventricle 22 is the tricuspid valve (TV) 23. The mitral valve 12 has two leaflets, extending downwards into the ventricular cavity, and is connected to the left ventricular wall via chordae tendineae 14 and papillary muscles 15. The tricuspid valve 23 has three leaflets, extending downwards into the ventricular cavity, and is connected to the right ventricular wall via chordae tendineae 24 and papillary muscles 25. When valves fail to open and close properly, they impair blood circulation. For example, mitral regurgitation or tricuspid regurgitation are extremely common types of valvular disease. In these conditions, an opening that cannot be closed occurs at the center or one side of the valve's occlusal margin. Edge-to-edge repair is a treatment method for these conditions, which involves aligning the valve leaflets at the opening to reduce the opening area when the valve closes and decrease the regurgitation rate.

[0083] When performing edge-to-edge repair of mitral or tricuspid regurgitation using transcatheter intervention, the operator precisely repairs the valve via catheter under image guidance (e.g., ultrasound). Due to the complex environment at the valve site and the normal beating of the heart during the procedure, improvements in the performance of the valve clamping device used to hold the valve are particularly important.

[0084] The following description is in conjunction with the accompanying drawings:

[0085] Please refer to Figure 2 This is a schematic diagram of the structure of a valve repair system provided in an embodiment of this application. Figure 2 As shown, the valve repair system includes a valve clamping device 100 and a delivery system 200. The delivery system 200 is used to deliver (or transport) and control the valve clamping device 100. The delivery system 200 includes a catheter 210 and a delivery device 220. The distal end of the catheter 210 is detachably connected to the valve clamping device 100 under the control of the delivery device 220. When the delivery device 220 delivers the valve clamping device 100 to the desired position through the catheter 210, it controls the valve clamping device 100 to complete the capture and clamping of the valve leaflets, and then controls the valve clamping device 100 to detach from the distal end of the catheter 210 and remain in the patient's body.

[0086] In one implementation, the delivery system 200 may employ a three-layer structure, wherein the catheter 210 (also referred to as a delivery sheath) comprises an outer guiding catheter 211 (also referred to as a guiding sheath), a middle manipulating catheter 212 (also referred to as a manipulating sheath), and an inner implantation catheter 213 (also referred to as an implantation sheath). The proximal end of the catheter 210 can be controlled via a control handle to move the distal end of the catheter 210, for example, as... Figure 2 As shown, the delivery system 200 includes a guide tube handle 221, a control catheter handle 222, and an implantation catheter handle 223, respectively disposed at the proximal ends of the guide tube 211, control catheter 212, and implantation catheter 213, for controlling the distal movement of the guide tube 211, control catheter 212, and implantation catheter 213. During operation, the guide tube handle 221 controls the distal movement of the guide tube 211, allowing the guide tube 211 to enter the patient's body and providing an operating channel for the control catheter 212; the control catheter handle 222 controls the distal movement of the control catheter 212, providing an operating channel for the implantation catheter 213. The guide tube 211 and control catheter 212 can be, for example, adjustable catheters, allowing for omnidirectional bending (anterior-posterior, lateral, and lateral), providing flexibility and convenience for the operation. The valve clamping device 100 is detachably disposed at the distal end of the implantation catheter 213, and the implantation catheter handle 223 controls the distal movement of the implantation catheter 213, delivering the valve clamping device 100 to the affected area. A delivery rod can be installed inside the implanted catheter 213. Figure 2(Not shown in the figure, see 214 in the following figures), and a control mechanism 2231 (e.g., a control handle) can be provided on the implantation catheter handle 223. This control mechanism 2231 is connected to the proximal end of the delivery rod, and the distal end of the delivery rod provides a driving force to the valve clamping device 100 to control the state of the valve clamping device 100, thereby realizing the capture and clamping of the valve leaflets by the valve clamping device 100. Furthermore, other control mechanisms can be provided on the implantation catheter handle 223 to control other operations of the valve clamping device 100. For example, a control mechanism can also be provided to control the state of the grasping member of the valve clamping device 100, so as to control the grasping member to open toward the clamping member during the capture of the valve leaflets, so as to capture the valve leaflets; another example is that a control mechanism can also be provided to control the connection state between the valve clamping device 100 and the distal end of the implantation catheter 213, so as to control the valve clamping device 100 to disengage from the distal end of the implantation catheter 213 after the capture and clamping of the valve leaflets is completed.

[0087] Furthermore, the above delivery system 200 can be mounted on a support, which can provide support for the delivery system 200 and improve the stability of the valve repair system.

[0088] The above implementation of the conveying system 200 is merely an example. In other embodiments, other structures may be adopted. For example, the control handle and the control mechanism on the control handle may be adjusted so that some of the functions of the control handle are integrated together, or the control mechanism on the control handle may be set independently, or some control functions may be integrated or separated on the control handle, etc. This application is not limited to the structure of the conveying system 200.

[0089] The valve clamping device is described below with reference to the accompanying drawings. Figure 3 This is a schematic diagram of the distal enlarged valve clamping device of a valve repair system provided in an embodiment of this application. To better illustrate the structure of the valve clamping device, the covering membrane is not shown. Figure 3As shown, the valve clamping device 100 includes a main body 110 and a clamping body 120, wherein the main body 110 is used to mount the clamping body 120, that is, the clamping body 120 is mounted on the main body 110; or, the main body 110 is used to provide support for the clamping body 120. Furthermore, the clamping body 120 can open and close relative to the main body 110. The clamping body 120 includes a clamping member 121 (also called a clamping arm) and a grasping member 122 (also called a grasping arm). Both the clamping member 121 and the grasping member 122 can open and close relative to the main body 110, and their opening and closing movements can be independent of each other. Thus, when the clamping member 121 opens relative to the main body 110, the grasping member 122 can close, and there can be space between the clamping member 121 and the grasping member 122 to facilitate the capture of the valve leaflets. When the leaflet is located between the clamping member 121 and the grasping member 122, the grasping member 122 can be controlled to open towards the clamping member 121, clamping the leaflet between the grasping member 122 and the clamping member 121 to achieve leaflet capture. Then, the clamping body 120 is further controlled to clamp with the main body 110 to complete the clamping and aligning of the leaflet. The proximal end of the main body 110 is detachably connected to the distal end of the delivery system 200 via the clutch device 215 (e.g., the distal end of the implantation catheter 213 detachably connected to the delivery system 200). When the clamping body 110 completes the clamping and aligning of the leaflet, the main body 110 can be controlled to detach from the distal end of the delivery system 200, so that the valve clamping device 100 remains in the patient's body to complete valve repair.

[0090] The number of clamps can be two or more. This application is not limited to the number of clamps. For ease of description, two are used as an example here. There can be more clamps in other embodiments, and the implementation of other clamps is the same as described in the embodiments of this application, so they will not be repeated here.

[0091] The valve clamping device 100 has a closed state and an open state, wherein the open state includes an inverted state. The following section uses mitral valve repair as an example to further illustrate this. Figures 4-14 Describe the different states of the valve clamping device 100 during the repair process. Figures 4-7 The valve clamping device 100 in the middle is not covered with a membrane to better show its structure; Figures 8-14 The valve clamping device 100 has a membrane to better display its status during the repair process. Repair of other valve structures (such as the tricuspid valve) is similar. Figure 4 This is a plan view of the valve clamping device in the closed state; Figures 5-7 These are plan views of the valve clamping device in different open states, where... Figure 7 The open state shown can also be called the inverted state. Figures 8-14 This is a schematic diagram of the valve clamping device during operation.

[0092] During the delivery of the valve clamping device 100, the valve clamping device 100 is in a closed state, such as... Figure 4 and Figure 8 As shown, the delivery system delivers the valve clamping device 100 to the affected area, specifically near the leaflets 131 and 132 of the mitral valve, via catheter 210. In the closed state, the clamping body 120 clamps (or attaches) to the main body 110, meaning the clamping element 121 and the grasping element 122 on the same side are joined together and both approach the main body 110. At this time, the valve clamping device 100 can enter the patient's body with minimal radial dimension, effectively reducing harm to the patient and alleviating discomfort.

[0093] like Figure 9 As shown, when the valve clamping device 100 is delivered to the target location (e.g., the affected area), the clamping member 121 is controlled to gradually open, that is, the angle between it and the main body 110 gradually increases, and the process of gradually increasing the angle is always in the open state. Figure 5 and Figure 9 This shows the open state of a valve clamping device 100.

[0094] like Figure 9 As shown, when the valve opens a large opening (i.e., the opening between leaflets 131 and 132) suitable for the valve clamping device 100 to pass through, the valve clamping device 100 can be inserted into the left ventricle. In this embodiment, the valve clamping device 100 in the open state is inserted into the left ventricle. In other embodiments, the valve clamping device 100 in the closed state can be inserted into the left ventricle, and then the clamping member 121 is controlled to gradually open.

[0095] like Figure 10 As shown, after the valve clamping device 100 is inserted into the left ventricle, the operator can adjust the position of the valve clamping device 100 via imaging and determine whether the opening state of the valve clamping device 100 is suitable for capturing the leaflets, that is, whether the clamping member 121 of the valve clamping device 100 is in the optimal capture position. When the opening state of the valve clamping device 100 is suitable for capturing the leaflets, the grasping member 122 can be controlled to open and move towards the clamping member 121 on the same side, capturing the leaflets between the grasping member 122 and the clamping member 121. For example, as... Figure 6 and Figure 11As shown, when the included angle α between the clamping members 121 facing the proximal end is obtuse and the leaflet is located between the clamping member 121 and the grasping member 122, the valve clamping device 100 is controlled to approach one leaflet of the valve (referred to as the first leaflet for distinction). When the first leaflet is located between the grasping member 122 and the clamping member 121 on one side, the grasping member 122 on that side is controlled to move towards the clamping member 121 on the same side, clamping the first leaflet between the grasping member 122 and the clamping member 121. Then, in the same manner, the valve clamping device 100 is controlled to approach the other leaflet of the valve (referred to as the second leaflet for distinction). When the second leaflet is located between the grasping member 122 and the clamping member 121 on the other side, the grasping member 122 on the other side is controlled to move towards the clamping member 121 on the same side, clamping the second leaflet between the grasping member 122 and the clamping member 121. Thus, as... Figure 12 As shown, the capture of the petal leaf is completed; the first petal leaf can be petal leaf 131, then the second petal leaf is petal leaf 132, or the first petal leaf can be petal leaf 132, then the second petal leaf is petal leaf 131.

[0096] Then, the clamping member 121 is controlled to close towards the main body 110. Since the grasping member 122 is located between the clamping member 121 and the main body 110, the clamping member 121 can drive the grasping member 122 to close, so that the valve clamping device 100 returns to the closed state. Figure 13 As shown. Unlike the closed state during delivery, the valve clamping device 100 clamps different leaflets, causing the captured (or seized) leaflets to align, achieving edge-to-edge repair. Finally, the valve clamping device 100 is disengaged from the distal end of the catheter 210, remaining in the patient's body. The valve clamping device 100 and the catheter 210 are connected by a clutch system or mechanism (or connection / disengagement system or mechanism). The clutch mechanism includes a connection structure 116 located proximal to the valve clamping device 100 and a clutch device 215 located distal to the catheter 210. During delivery and operation, as... Figures 8-13 As shown, the connection structure 116 at the proximal end of the valve clamping device 100 and the clutch device 215 remain connected. After capturing and clamping the valve leaflets, as... Figure 14 As shown, the control connection structure 116 is disengaged from the clutch device 215, allowing the valve clamping device 100 in the closed state to remain in the patient's body after detaching from the distal end of the catheter 210. In the closed state, the clamping body 120 has a very small angle with the main body 110, so the main body 110 can fill the space between the clamping bodies 120, improving the stability of the clamping and reducing blood backflow.

[0097] The included angle between the clamping members 121 facing the proximal end can be further increased, so that in the event of leaflet capture failure, the valve clamping device 100 can be controlled to an inverted state, such as... Figure 7As shown, at this point, the included angle β between the clamping members 121 facing distally is an acute angle, which facilitates the retraction of the valve clamping device 100 from the ventricular side to the atrial side without entanglement with the chordae tendineae connecting the leaflets. This makes it easier for the operator to control and reduces damage to the patient's internal tissues caused by the valve clamping device 100. Afterwards, the position and state of the valve clamping device 100 can be readjusted, and the above leaflet capture and clamping steps can be repeated until the leaflet clamping is completed.

[0098] The valve clamping device 100 can switch between the above states, and can be in the above states. Figures 4-7 In any of the states shown, there can also be any intermediate state between two adjacent states, and any state other than the closed state can be understood as an open state.

[0099] The valve clamping device and valve repair system provided in the following embodiments of this application can be used not only to repair mitral and tricuspid valves, but also to repair other similar valve structures.

[0100] In some respects, the stability of valve clipping devices is of great significance for reducing surgical difficulty and improving repair outcomes. Therefore, some embodiments of this application provide a valve clipping device and valve repair system that offer better stability during operator use, thereby reducing the difficulty of operation.

[0101] In the embodiments of this application, the main body 110 employs a segmented transmission structure (hereinafter referred to as a transmission assembly) to drive the movement of the clamping member 121, thereby improving the stability of the valve clamping device 100. This segmented transmission assembly has a first segment and a second segment, with a transmission structure between the first and second segments. This transmission structure provides axial movement transmission while reducing (or preventing) the transmission of radial movement tendencies to the second segment; in other words, the transmission structure does not provide radial movement transmission (it can be understood that the transmitted radial movement is negligible). In the embodiments of this application, radial movement can also be referred to as radial rotation.

[0102] To deliver and control the implant more stably (e.g., the valve clamping device 100 in this embodiment), the control mechanism 2231 at the proximal end of the delivery system 200 typically rotates the delivery rod 214 to move axially. At this time, both the radial and axial movements of the proximal end of the delivery rod 214 are transmitted to the main body 110 through the distal end of the delivery rod 214. After the main body 110 adopts a segmented structure, the radial movement is transmitted to the first segment of the main body 110 and then isolated from the second segment to reduce the transmission of the radial movement trend to the second segment. At this time, the second segment drives the opening and closing movement of the clamping member 121, making the movement of the clamping member 121 tend to be a continuous and stable change. During operation, the valve clamping device 100 has a more stable state, which is beneficial for the operator to control the clamping member 121 and reduces the difficulty of operation.

[0103] As can be seen, the valve clamping device 100 can control the rotation pitch of the delivery rod 214 through the control mechanism 2231, so that the movement of the clamping member 121 tends to be continuous. The included angle between the clamping members 121 towards the proximal end can be a continuous angle between 0° and 300°, which is beneficial for the operator to control the clamping member 121, and the adaptability to different leaflet thicknesses is also improved, thus broadening the applicable scenarios for transcatheter intervention edge-to-edge repair.

[0104] The following description is in conjunction with the accompanying drawings. Please refer to them. Figures 15-17 It illustrates the structure of a main body 110 provided in an embodiment of this application. Under the main body structure of this embodiment, Figure 15 yes Figure 4 A cross-sectional view of the main body 110 of the valve clamping device shown along the AA direction; Figure 16 yes Figure 5 (or Figure 6 A cross-sectional view of the main body 110 of the valve clamping device shown in the figure along the AA direction; Figure 17 yes Figure 7 A cross-sectional view of the main body 110 of the valve clamping device shown along the AA direction.

[0105] like Figures 15-17 As shown, the main body 110 includes a transmission assembly 111, which includes a first connecting rod 1111 and a second connecting rod 1112. A transmission structure 1113 is provided at the distal end of the first connecting rod 1111 and the proximal end of the second connecting rod 1112. The transmission structure 1113 transmits axial movement between the first connecting rod 1111 and the second connecting rod 1112. The first connecting rod 1111 is also called the first transmission rod, and the second connecting rod 1112 is also called the second transmission rod. The clamping member 121 of the clamping body 120 is hinged to the distal end of the second connecting rod 1112, so that the axial movement of the second connecting rod 1112 drives the opening and closing movement of the clamping member 121, changing the angle between the clamping member 121 and the main body 110.

[0106] The transmission structure 1113 transmits axial motion between the first link 1111 and the second link 1112, meaning that the transmission structure 1113 transmits the axial motion of the first link 1111 to the second link 1112, and / or, the transmission structure 1113 transmits the axial motion of the second link 1112 to the first link 1111. While the transmission structure 1113 transmits axial motion between the first link 1111 and the second link 1112, the degree of radial motion transmission is negligible or non-existent. In other words, the transmission structure 1113 isolates the radial force acting on the first link 1111, thus ensuring that the second link 1112 only performs axial motion. In other words, the driving force of the valve clamping device 100 acts radially on the first link 1111, and the transmission structure 1113 transmits axial motion while preventing the radial motion tendency from being transmitted to the second link 1112.

[0107] The above embodiments, through a segmented design, ensure that the radial force in the driving force of the valve clamping device acts on the first segment, and while transmitting axial movement using a transmission structure, prevent (or reduce) the transmission of radial force to the second segment. The clamping component is hinged on the second segment, so that the second segment only performs axial movement to drive the opening and closing of the clamping component. This makes the movement of the clamping component tend to be continuous and stable, thus the valve clamping device has a more stable state during operation, which is beneficial for the operator to control the clamping component and reduces the difficulty of operation.

[0108] Furthermore, compared to the prior art, by setting a telescopic rod and setting a connecting rod hinged to the clamping member on the outer wall of the telescopic rod, so that the telescopic rod can drive the clamping member to move through the connecting rod when it extends and retracts, the structural setting of the embodiment of this application is simpler, reducing the factors that cause the valve clamping device to be unstable, and can improve the stability of the valve clamping device to a certain extent.

[0109] In one implementation, the control mechanism 2231 of the delivery system 200, which controls the state of the valve clamping device 100, provides a driving force to the valve clamping device 100 via a delivery rod 214. This driving force can be generated by clockwise or counterclockwise radial rotation. The driving force acts on the first link 1111. In the first driving mode (e.g., clockwise or counterclockwise), the driving force drives the first link 1111 to make radial and axial movements. The transmission structure 1113 transmits axial movement between the first link 1111 and the second link 1112 and reduces the transmission of radial movement, so that the second link 1112 makes axial movement. In the second driving mode (e.g., counterclockwise or clockwise), the driving force drives the first link 111 to make radial movement and drives the second link 1112 to make axial movement. The transmission structure 1113 transmits axial movement between the first link 1111 and the second link 1112 and reduces the transmission of radial movement, so that the second link 1112 only makes axial movement under the action of the driving force.

[0110] It can be seen that when the first link 1111 or the second link 1112 moves axially, the axial force generated by the transmission structure 1113 between the first link 1111 and the second link 1112 is sufficient to drive the axial movement of the second link 1112 or the first link 1111; while when the first link 1111 moves radially, the radial force generated by the transmission structure 1113 between the first link 1111 and the second link 1112 is insufficient to drive the radial movement of the second link 1112.

[0111] The transmission system of the above-mentioned segmented valve clamping device can be understood as including a proximal transmission system and a distal transmission system. The proximal transmission system and the distal transmission system are axially limited to transmit axial movement, while the radial movement is not limited to reduce the tendency of radial movement to be transmitted to the distal transmission system.

[0112] The above transmission structure 1113 can be realized by an axial limiting structure. This axial limiting structure has no radial limiting, and the radial friction is small, which is insufficient to transmit radial motion.

[0113] The axial limiting structure includes a first limiting structure and a second limiting structure that can mutually limit each other. They are configured to transmit axial motion while reducing the tendency to transmit radial motion. When the first link 1111 drives the first limiting structure to move radially, the radial motion is not transmitted to the second link 1112. This configuration is simple, effective, and facilitates processing and assembly.

[0114] In one implementation, the transmission structure 1113 includes a first limiting structure 1113-1 and a second limiting structure 1113-2. The first limiting structure 1113-1 is disposed at the distal end of the first connecting rod 1111, and the second limiting structure 1113-2 is disposed at the proximal end of the second connecting rod 1112. When the first connecting rod 1111 or the second connecting rod 1112 moves axially, the first limiting structure 1113-1 and the second limiting structure 1113-2 abut against each other axially.

[0115] The first limiting structure 1113-1 and the second limiting structure 1113-2 can limit each other, so that the first link 1111 and the second link 1112 remain connected during axial movement. In this way, the first link 1111 and the second link 1112 can transmit axial movement to each other.

[0116] In one implementation, the first limiting structure 1113-1 is integrally formed with the first connecting rod 1111, and the second limiting structure 1113-2 is integrally formed with the second connecting rod 1112. Thus, the valve clamping device 100 has a simple connection design, better stability, and lower cost.

[0117] In other embodiments, a non-integral molding design may also be adopted. For example, the first limiting structure 1113-1 is integrally molded with the first connecting rod 1111, and the second limiting structure 1113-2 is fixedly connected to the second connecting rod 1112; or, the first limiting structure 1113-1 is fixedly connected to the first connecting rod 1111, and the second limiting structure 1113-2 is integrally molded with the second connecting rod 1112; or, the first limiting structure 1113-1 is fixedly connected to the first connecting rod 1111, and the second limiting structure 1113-2 is fixedly connected to the second connecting rod 1112.

[0118] Furthermore, to reduce the difficulty of integral molding, the first limiting structure 1113-1 is formed at the distal end of the first connecting rod 1111 and has an inwardly extending extension, such that the opening size of the distal end of the first connecting rod 1111 is smaller than the internal space (or cavity) size of the first connecting rod 1111. The second limiting structure 1113-2 is formed at the proximal end of the second connecting rod 1112 and has an outwardly extending extension. Thus, after the proximal end of the second connecting rod 1112 enters the internal space of the first connecting rod 1111, the first limiting structure... The extension of 1113-1 and the second limiting structure 1113-2 axially abuts, so that when the second link 1112 moves axially to the far end, it drives the first link 1111 to move axially. As independent components, the first link 1111 and the second link 1112 are designed with limiting structures so that the radial friction of the first link 1111 and the second link 1112 is insufficient to drive the radial movement of the second link 1112, thereby reducing the tendency of the radial movement of the first link 1111 to be transmitted to the second link 1112.

[0119] The axial contact of the first limiting structure 1113-1 and the second limiting structure 1113-2 restricts the relative movement of the first connecting rod 1111 and the second connecting rod 1112 in one axial direction, for example... Figures 15-17 In this design, the movement of the first link 1111 proximally relative to the second link 1112 is restricted, and the movement of the second link 1112 distally relative to the first link 1111 is restricted. This allows the first link 1111 to move proximally, which in turn drives the second link 1112 to move proximally, and vice versa. This limiting method is relatively simple in structure, easy to manufacture, and has low cost.

[0120] In other embodiments, the axial contact of the first limiting structure 1113-1 and the second limiting structure 1113-2 restricts the relative movement of the first link 1111 and the second link 1112 in two axial directions. One implementation is as follows: Figure 18 As shown: the second limiting structure 1113-2 has a concave side surface, and the first limiting structure 1113-1 has an extension extending inward toward the first connecting rod 1111, the extension being located within a groove on the concave side surface. The groove is arranged circumferentially around the second limiting structure 1113-2, which facilitates radial movement of the first connecting rod 1111 relative to the second connecting rod 1112, without transmitting radial movement to the second connecting rod 1112. Optionally, the first limiting structure 1113-1 is integrally formed with the first connecting rod 1111, and the second limiting structure 1113-2 is fixedly connected to or integrally formed with the second connecting rod 1112.

[0121] The above bidirectional limiting structure can bring the following benefits:

[0122] 1. The axial movement of the second link 1112 toward the distal end can be driven by the movement of the first limiting structure 1113-1 toward the distal end, without the need for the abutment and push of the distal end of the delivery rod. The length of the distal part of the delivery rod that penetrates into the first link 1111 can be shortened, which is beneficial to the control of the delivery rod.

[0123] 2. The contact area between the first limiting structure 1113-1 and the second limiting structure 1113-2 is small, which helps to reduce the tendency of radial motion transmission.

[0124] In some embodiments, the limiting structure can be disposed on the connecting rod as a limiting member independently of the connecting rod. For example, the first limiting structure can be a limiting member independent of the first connecting rod, or the second limiting structure can be a limiting member independent of the second connecting rod; or, both the first limiting structure and the second limiting structure can be set as limiting members independent of the first connecting rod and the second connecting rod.

[0125] In some embodiments, the first limiting structure is a limiting member disposed at the distal end of the first connecting rod 1111, the limiting member having a cavity with an opening to the distal end, the second connecting rod 1112 passing through the opening, and a second limiting structure at the proximal end of the second connecting rod 1112 being accommodated in the cavity, wherein the maximum size of the second limiting structure is larger than the size of the opening. Alternatively, the second limiting structure is a limiting member disposed at the proximal end of the second connecting rod 1112, the limiting member having a cavity with an opening to the proximal end, the distal end of the first connecting rod 1111 passing through the opening, and a first limiting structure at the distal end of the first connecting rod 1111 being accommodated in the cavity, wherein the maximum size of the first limiting structure is larger than the size of the opening. The introduction of the limiting member brings more flexible configuration to the transmission structure, and each configuration has its own advantages. Optionally, the limiting member can also be referred to as a hub.

[0126] The following describes several implementation methods with reference to the attached diagram:

[0127] One implementation method is as follows Figure 19 As shown, the first limiting structure is a limiting member 1113-1' disposed at the distal end of the first connecting rod 1111. For example, the proximal end of the limiting member 1113-1' is fixedly connected to the first connecting rod 1111 and located near the distal end of the first connecting rod 1111. The limiting member 1113-1' has a chamber C1 with an opening to the proximal end, such that the distal end 1111-3 of the first connecting rod 1111 extends from the proximal end of the limiting member 1113-1' into the chamber C1; the chamber C1 also has an opening to the distal end, such that the proximal end of the second connecting rod 1112 extends from the distal end of the limiting member 1113-1' into the chamber C1, and the proximal end of the second connecting rod 1112 has a second limiting structure 1113-2, which is accommodated within the chamber C1.

[0128] During axial transmission (or axial movement) to the distal end, the distal end 1111-3 of the first connecting rod 1111 abuts against the second limiting structure 1113-2. The distal opening of chamber C1 only allows (or just allows) the passage of the second connecting rod 1112. The maximum size of the second limiting structure 1113-2 is larger than the size of the distal opening. Therefore, during axial transmission (or axial movement) to the proximal end, the distal end of the limiting member 1113-1' abuts against the second limiting structure 1113-2. Furthermore, the limiting member 1113-1' can rotate relative to the second connecting rod 1112.

[0129] With the above structure, the proximal transmission system where the first link is located becomes the main transmission system, and the distal transmission system where the second link is located becomes the passive transmission system, which has the following benefits for the performance of the valve clamping device:

[0130] 1. The axial length of the internal space 1111-1 of the first link 1111 can be shortened. Correspondingly, the length of the distal part of the delivery rod that extends into the internal space 1111-1 of the first link 1111 is shortened. The shortened delivery rod is more conducive to the transmission of torque on the control mechanism acting on the proximal end of the delivery rod, resulting in better control performance.

[0131] 2. In the two axial directions of movement, the distal part of the delivery rod only acts on the first connecting rod 1111, and the axial movement is achieved by rotation, which reduces the number of parts that interact with the distal end of the delivery rod and is beneficial to the performance stability of the valve clamping device 100.

[0132] 3. The distal end 1111-3 of the first link abuts against the second limiting structure 1113-2 of the proximal end of the second link, resulting in higher power transmission efficiency when the transmission system moves axially to the distal end.

[0133] Another implementation method is as follows Figure 20 As shown, the second limiting structure is a limiting member 1113-2' disposed at the proximal end of the second connecting rod 1112. For example, the distal end of the limiting member 1113-2' is fixedly connected to the second connecting rod 1112 and located near the proximal end of the second connecting rod 1112. The limiting member 1113-2' has a chamber C2 with an opening to the proximal end, such that the distal end of the first connecting rod 1111 extends from the proximal end of the limiting member 1113-2' into the chamber C2, and the distal end of the first connecting rod 1111 has a first limiting structure 1113-1, which is accommodated within the chamber C2; the chamber C2 also has an opening to the distal end, such that the proximal end 1112-1 of the second connecting rod 1112 extends from the distal end of the limiting member 1113-2' into the chamber C2.

[0134] During axial transmission (or axial movement) to the distal end, the first limiting structure 1113-1 at the distal end of the first link 1111 abuts against the proximal end 1112-1 of the second link 1112. The proximal opening of chamber C2 allows only the first link 1111 to pass through. The maximum size of the first limiting structure 1113-1 is larger than the size of this proximal opening; therefore, during axial transmission (or axial movement) to the proximal end, the proximal end of the limiting member 1113-2' abuts against the first limiting structure 1113-1. Furthermore, the first link 1111 can rotate relative to the limiting member 1113-2'.

[0135] The above structure also makes the proximal drive system, where the first link is located, the main drive system, and the distal drive system, where the second link is located, the passive drive system, thus providing the same performance as the valve clamping device 100. Figure 19 The benefits are similar to those shown in the structure.

[0136] Another implementation method is as follows Figure 21As shown, the first limiting structure is a limiting member 1113-1' provided at the distal end of the first connecting rod 1111. Different from Figure 19 the implementation shown, there is no opening at the proximal end of the limiting member 1113-1'. The second limiting structure 1113-2 at the proximal end of the second connecting rod 1112 is accommodated in the chamber C3.

[0137] When axially driving towards the distal end (or axially moving towards the distal end), the inner wall of the proximal end of the limiting member 1113-1' abuts against the second limiting structure 1113-2. The opening of the chamber C3 towards the distal end only allows the second connecting rod 1112 to pass through, and the maximum dimension of the second limiting structure 1113-2 is larger than the dimension of the opening towards the distal end. Therefore, when axially driving towards the proximal end (or axially moving towards the proximal end), the distal end of the limiting member 1113-1' abuts against the second limiting structure 1113-2. In addition, the limiting member 1113-1' can rotate relative to the second connecting rod 1112.

[0138] The above structure also makes the proximal transmission system where the first connecting rod is located become the main transmission system, and the distal transmission system where the second connecting rod is located become the passive transmission system, which has similar benefits to the performance of the valve clamping device 100 as Figure 19 the structure shown.

[0139] In addition, the axial length of the limiting member 1113-1' can be further shortened, and then the axial length of the valve clamping device 100 can be further shortened, which is more beneficial for the transcatheter delivery of the valve clamping device 100 and the implantation operation in an organ (such as the heart).

[0140] The first limiting structure or the second limiting structure in each of the above embodiments can be set to be spherical or ellipsoidal, that is, the cross-section is circular or elliptical. When the second limiting structure is spherical or ellipsoidal, it can be set that the first limiting structure has a receiving space for accommodating the second limiting structure, and this receiving space allows the second connecting rod to pass through, but does not allow the second limiting structure to pass through, that is, the maximum dimension of the second limiting structure is larger than the opening of the receiving space. When the first limiting structure is spherical or ellipsoidal, it can be set that the second limiting structure has a receiving space for accommodating the first limiting structure, and this receiving space allows the first connecting rod to pass through, but does not allow the first limiting structure to pass through, that is, the maximum dimension of the first limiting structure is larger than the opening of the receiving space.

[0141] With such a setting, the contact area between the components of the transmission structure at the distal end of the first connecting rod 1111 and the proximal end of the second connecting rod 1112 is small, which is beneficial for further reducing the transmission trend of the radial movement.

[0142] Furthermore, the inner wall of the accommodating space for housing the spherical or ellipsoidal limiting structure can be configured as opposing slopes to better fit the limiting structure contained therein. Thus, the contact area between the first and second limiting structures is small, and the angle with the radial direction further helps to reduce the tendency for radial movement to be transmitted.

[0143] The above limiting structure scheme can be applied to embodiments that include limiting members, wherein the limiting structure housed within the cavity of the limiting member is spherical or ellipsoidal. For example, as... Figure 22 and Figure 23 As shown, the second limiting structure 1113-2 disposed on the second connecting rod 1112 is spherical and is accommodated within the chamber C4 of the limiting member 1113-1'. Similarly, in other embodiments, the first limiting structure located in the chamber of the limiting member is spherical or ellipsoidal. Furthermore, the inner wall of the chamber of the limiting member can be configured as opposing inclined surfaces or curved surfaces to better adapt to the limiting structure accommodated therein, for example, as... Figure 24 As shown, the inner wall of the chamber C5 of the limiting member 1113-1' has opposing arc surfaces.

[0144] The opening of the chamber in the above-mentioned limiting member is just large enough to allow the first connecting rod 1111 and / or the second connecting rod 1112 to pass through, so as to limit the radial sway of the connecting rod and improve the stability of the valve clamping device 100.

[0145] In the above embodiments with a cavity, optionally, one or both of the first and second limiting structures are elastic, i.e., made of an elastic material. This facilitates the installation of the limiting structure extending into the cavity, for example, in... Figure 19 , Figure 21 and Figure 22 In the illustrated embodiment, the installation of the second limiting structure 1113-2 is facilitated. Figure 20 In the illustrated embodiment, the installation of the first limiting structure 1113-1 is facilitated. The elastic material is, for example, a material with a certain degree of flexibility, such as rubber or silicone.

[0146] In some embodiments of this application, during the transcatheter delivery of the valve clamping device 100, the movement of the clamping member 121 is controlled by an elongated delivery rod 214 of the delivery system 200. See also Figure 25 The first link 1111 has an internal space 1111-1. The distal end of the delivery rod 214 of the conveying system 200 is adapted to penetrate into the internal space 1111-1 of the first link 1111, while the proximal end of the delivery rod 214 is connected to the control mechanism 2231. An operator can axially move the delivery rod 214 by rotating the control mechanism 2231 at the proximal end of the conveying system 200.

[0147] In one implementation, the outer wall of the delivery rod 214 abuts against the inner space wall of the first connecting rod 1111, and the friction between the delivery rod 214 and the first connecting rod 1111 drives the first connecting rod 1111 to move. When the delivery rod 214 drives the first connecting rod 1111 to move, it overcomes the resistance force. For example, in the hinge structure formed by the fixed pin, the moving pin and the corresponding track structure, it overcomes the friction between the moving pin 115 and the moving pin track 1125 on the support member 112, and the friction between the fixed pin 114 and the fixed pin track 1211-2; in addition, it overcomes the self-weight of the second connecting rod 1112. The movement of the first connecting rod 1111 includes axial movement and radial movement. The axial movement between the first connecting rod 1111 and the second connecting rod 1112 can be transmitted to change the state of the valve clamping device 100 to capture and clamp the leaflets. After achieving the purpose of edge-to-edge repair, the delivery rod 214 disengages from the first connecting rod 1111.

[0148] The shape of the distal portion of the delivery rod 214 and the shape of the internal space 1111-1 of the first link 1111 can be mutually coordinated, so that the operation of the proximal end of the delivery rod 214 can be transmitted and acted upon by the first link 1111. In one implementation, neither the shape of the distal portion of the delivery rod 214 nor the cross-sectional shape of the internal space 1111-1 of the first link 1111 is circular, i.e., non-circular. For example, the cross-section of the internal space 1111-1 of the first link 1111 is elliptical, rectangular, or triangular; or, for example, the cross-section of the internal space 1111-1 of the first link 1111 is racetrack-shaped, including two parallel sides and a symmetrical arc connecting the two sides. The distal cross-section of the delivery rod 214 can be a regular or irregular shape, as long as it matches the cross-section of the internal space 1111-1 to achieve contact. For example, the distal cross-section of the delivery rod 214 can be rectangular (including square) or other polygonal.

[0149] Thus, when the delivery rod 214 moves radially, the distal end of the delivery rod 214 is inside the first link 1111 and can only rotate at a very small angle. The edge then abuts against the inner space wall of the first link 1111, thereby driving the first link 1111 to move axially and radially.

[0150] In other embodiments, the cross-section of the internal space 1111-1 of the first link 1111 can also be other regular or irregular shapes, and the delivery rod 214 can also be set to other regular or irregular shapes, as long as the delivery rod can quickly abut against the internal space 1111-1 of the first link 1111 when it moves radially.

[0151] In some embodiments, such as Figures 15-18As shown, the internal space 1111-1 of the first link 1111 extends through the first link 1111, and the delivery rod 214 can pass through the internal space 1111-1 of the first link 1111 and abut against the second link 1112. When the control mechanism 2231 controlling the delivery rod 214 rotates in the first direction (clockwise or counterclockwise) and pushes the delivery rod 214 axially towards the proximal end, the delivery rod 214 abuts against the inner wall of the internal space 1111-1 of the first link 1111, causing the first link 1111 to move proximally. The first link 1111 drives the first limiting structure 1113-1, the first limiting structure 1113-1 drives the second limiting structure 1113-2, and then drives the second link 1112 to move axially towards the proximal end; at this time, the valve clamping device 100 changes from a closed state to an open state. When the control mechanism 2231 controlling the delivery rod 214 rotates in the second direction (counterclockwise or clockwise), pushing the delivery rod 214 axially towards the distal end, the distal end of the delivery rod 214 abuts against the proximal end of the second limiting structure 1113-2, pushing the second connecting rod 1112 towards the distal end. The second connecting rod 1112 drives the second limiting structure 1113-2, which in turn drives the first limiting structure 1113-1, thereby driving the first connecting rod 1111 axially towards the distal end. At this time, the valve clamping device 100 can move from the open state to the closed state. It can be seen that from the closed state to the open state (including the inverted state), the first limiting structure 1113-1 drives the second limiting structure 1113-2, and in the reverse movement, the second limiting structure 1113-2 drives the first limiting structure 1113-1.

[0152] In some embodiments, such as Figures 19-24 As shown, the internal space 1111-1 of the first link 1111 is shortened and does not penetrate the first link 1111. In this embodiment, the axial movement of the first link 1111 towards the distal end drives the second link 1112 to move axially towards the distal end. It is not necessary for the distal end of the delivery rod 214 to abut against the second link 1112 or the second limiting structure 1113-2 to push it. In this way, the length of the distal end of the delivery rod 214 extending into the internal space 1111-1 of the first link 1111 can be reduced. The shortening of the delivery rod is more conducive to the transmission of torque acting on the handle at the proximal end of the delivery rod, resulting in better control performance. Figure 18 The illustrated embodiments can also be modified in a similar way.

[0153] Similar to the embodiments described above, in some embodiments of this application, the main body 110 of the valve clamping device 100 may further include an attachment 113. A first connecting rod 1111 is disposed within the attachment 113. The attachment 113 may be, for example, an attachment sleeve. Clamping members 121 and gripping members 122 may be disposed on the periphery of the attachment 113 via a support member 112. For example, a pair of clamping members 121 are respectively located on both sides of the attachment 113, and similarly, a pair of gripping members 122 are respectively located on both sides of the attachment 113.

[0154] In some embodiments of this application, a locking structure (or locking system) may be provided in the valve clamping device 100 to better lock and retain the valve clamping device 100 in the implantation position after the valve leaflets have been captured and clamped. This locking structure can be implemented using a threaded structure, for example, see [link to relevant documentation]. Figure 26 and Figure 27 In one specific embodiment, the inner wall of the attachment 113 is provided with an internal thread 1131, and the outer wall of the first connecting rod 1111 is provided with an external thread 1111-2, the internal thread 1131 and the external thread 1111-2 are helically matched. In this way, when the first connecting rod 1111 moves axially by rotating through the thread, each step of the movement can be locked by the thread.

[0155] The embodiments of this application do not limit the length (or number) and position of the internal and external threads on the attachment 113 and the first connecting rod 1111.

[0156] The above-mentioned locking structure provides the following benefits to the performance of the valve clamping device 100:

[0157] 1. The opening angle of the clamping member 121 can be locked at any time, and there is no need to set up a special control mechanism for the locking system in the conveying system. The operator only needs to rotate the delivery rod to control the movement of the clamping member 121. At the same time, the state of the clamping member 121 is automatically locked. By continuing to rotate the delivery rod, the clamping member 121 can continue to move. The operation steps are simple and effective.

[0158] 2. The first connecting rod and the attachment have a threaded connection, which makes the transmission system move more stably along the axial direction and is conducive to precise control of the clamping part 121.

[0159] During the movement of a transmission component (or transmission system), it is desirable to efficiently transmit axial motion between two mating surfaces while minimizing radial rotational transmission. Therefore, certain features can be designed on the mating surfaces to reduce the contact area between them. For example, at least one of the mating surfaces in the transmission component has a raised structure, which may include, for example, a contact surface with an arc-shaped cross-section.

[0160] In different embodiments, the abutting surfaces are not the same; for example, in Figures 15-17 In the illustrated embodiment, a protruding structure may be provided on at least one of the surfaces of the first limiting structure 1113-1 and the second limiting structure 1113-2 that axially abut against each other; optionally, the first limiting structure 1113-1 and the second connecting rod 1112 may or may not be in radial contact, and when in contact, at least one of the surfaces of the first limiting structure 1113-1 and the second connecting rod 1112 that radially abut against each other may be provided with a protruding structure. For example, in... Figure 18 In the illustrated embodiment, at least one of the axially abutting surfaces of the first limiting structure 1113-1 and the second limiting structure 1113-2 is provided with a protruding structure; optionally, the first limiting structure 1113-1 and the second limiting structure 1113-2 may or may not be in radial contact, and when in contact, at least one of the radially abutting surfaces may be provided with a protruding structure. Figure 19 In the illustrated embodiment, at least one of the surfaces of the limiting member 1113-1' and the second limiting structure 1113-2 that axially abut each other, and the surfaces of the distal end 1111-3 of the first connecting rod 1111 that axially abut each other with the second limiting structure 1113-2, are provided with protruding structures. Similarly, if there are surfaces abutting radially, protruding structures can also be provided. Figure 20 In the illustrated embodiment, at least one of the surfaces where the limiting member 1113-2' and the first limiting structure 1113-1 axially abut each other, and the surfaces where the proximal end 1112-1 of the second connecting rod 1112 and the first limiting structure 1113-1 axially abut each other, are provided with protruding structures. Similarly, if there are surfaces abutting radially, protruding structures can also be provided. Figure 21 In the illustrated embodiment, at least one of the surfaces of the limiting member 1113-1' and the second limiting structure 1113-2 that axially abut each other is provided with a protruding structure. Similarly, if there are surfaces that abut each other radially, a protruding structure can also be provided. In each of the above embodiments, with Figure 25 In the embodiment shown, at least one of the following surfaces is provided with a protruding structure: the distal end face of the delivery rod 214, the proximal end face of the second connecting rod 1112, and the distal end face of the internal space 1111-1 of the first connecting rod 1111.

[0161] The above-mentioned protruding structure can further reduce the transmission of radial motion and improve the transmission efficiency of axial motion, thereby further improving the stability of the clamping part 121 during operation.

[0162] The cross-section of any of the above contact surfaces can be as follows: Figure 28 As shown, the edges have rounded chamfers to reduce the area of ​​the contact portion and decrease the tendency for radial motion to be transmitted, while the retained planar portion ensures efficient motion transmission; in some embodiments, the area of ​​the contact surface can be further reduced by using a partially spherical surface (e.g., a hemispherical surface), such as... Figure 29As shown. In some embodiments, one or more spherical or partially spherical (e.g., hemispherical) microstructures are provided on the abutment surface to reduce the area of ​​the abutment surface, such as... Figure 30 As shown.

[0163] In other embodiments, other structural arrangements may be adopted to reduce the contact area between the limiting structure and the connecting rod, between the limiting structure and the limiting structure, between the connecting rod and the connecting rod in the transmission assembly, and to reduce the contact area between the delivery rod and the connecting rod. These will not be elaborated here, but are all within the protection scope of this application.

[0164] Similar to the embodiments above, in some embodiments of this application, the main body 110 of the valve clamping device 100 may further include a support member 112, which is sleeved on the second connecting rod 1112. The support member 112 may be disposed on the attachment member 113 and directly connected to the attachment member 113, or the support member 112 may be indirectly connected to the attachment member 113 through the second connecting rod 1112.

[0165] The distal end of the second connecting rod 1112 is located inside the support member 112 and is hinged to the clamping member 121. The axial movement of the second connecting rod 1112 drives the opening and closing movement of the clamping member 121, changing the angle between the clamping member 121 and the main body 110. The connecting part of the clamping member 121 extends into the support member 112 and can be connected to the support member 112 by a pin.

[0166] The hinge of the clamping member 121 and the second connecting rod 1112 can be a direct hinge or an indirect hinge. The hinge form can be various. This embodiment is not limited to the hinge form. As long as the axial movement of the second connecting rod 1112 can drive the clamping member 121 to perform opening and closing movements, it is acceptable.

[0167] In some respects, the state changes of valve clipping devices and the miniaturization of the overall structure are of great significance for the delivery of valve clipping devices and their operability in complex environments. They can reduce the difficulty of operation for surgeons and improve the repair effect.

[0168] In view of this, embodiments of this application provide a valve clamping device and a valve repair system. The structure of the clamping component has been optimized, and in conjunction with the setting of the support component, the valve clamping device has a more compact structure. At the same time, the compact structure supports a larger opening angle state change, which facilitates the operation of the surgeon. This reduces the difficulty of operating the valve clamping device in more complex environments, reduces the possible harm or discomfort to the patient, and thus improves the edge-to-edge repair effect.

[0169] The following description is in conjunction with the accompanying drawings:

[0170] Please refer to Figure 31 This is a three-dimensional structural schematic diagram of a valve clamping device provided in an embodiment of this application. Figure 31As shown, the main body 110 of the valve clamping device 100 includes a transmission component (not shown in the figure because it is located within the attachment 113) and a support component 112. The transmission component may be disposed within the attachment 113, and the support component 112 is located at the distal end of the main body 110 and connected to the attachment 113. The attachment 113 is, for example, an attachment sleeve, used to accommodate and protect the transmission component. In addition, a connecting structure 116 may be provided on the attachment 113 for connecting or disconnecting the valve clamping device 100 to the distal end of the catheter via a clutch device 215. In other embodiments, the main body 110 may not have an attachment component, and the connecting structure may be directly provided on the transmission component to achieve connection or disconnection with the catheter; furthermore, the support component may be sleeved on the distal end of the transmission component.

[0171] The transmission component can adopt the structure of the transmission component 111 in the above embodiments, or it can adopt a non-two-section structure or a telescopic structure, etc. This embodiment is not limited to this, but combined with the structure of the transmission component 111 in the above embodiments, the stability of the valve clamping device can be further improved.

[0172] The support member 112 has an internal accommodating space S with an external opening, and a fixing pin 114 passing through the accommodating space S. The distal end of the transmission member passes through the accommodating space S of the support member 112 and moves axially relative to the support member 112 under the action of a driving force. Please continue to refer to... Figures 32-36 These are schematic diagrams of different clamping components provided in the embodiments of this application, wherein... Figure 32 This is a three-dimensional structural diagram of a clamping component. Figure 33 for Figure 32 A plan view of the clamping assembly shown; Figure 34 A schematic diagram of the three-dimensional structure of another type of clamping component; Figure 35 This is a side view of yet another type of clamping component. Figure 36 for Figure 35The clamping member 121 is shown in another side view. The clamping member 121 includes a connecting portion 1211 and a clamping portion 1212, with the clamping portion 1212 connected to the connecting portion 1211. The connecting portion 1211 extends into the receiving space S through an opening in the support member 112. The connecting portion 1211 includes a moving pin hole 1211-1 and a fixed pin track 1211-2. The moving pin hole 1211-1 is located at the first end of the connecting portion 1211 and is used to connect the farthest end of the connecting portion 1211 away from the clamping portion 1212 to the far end of the transmission member within the receiving space S via a moving pin 115. The fixed pin track 1211-2 extends from the second end of the connecting portion 1211 near the clamping portion 1212 toward the first end to intersect with the moving pin hole 1211-1. Adjacent; the moving pin 115 passes through the moving pin hole 1211-1 and the far end of the transmission member; thus, the axial movement of the transmission member drives the axial movement of the moving pin 115, the fixed pin 114 passes through the fixed pin track 1211-2, and the axial movement of the moving pin 115 changes the position of the fixed pin 114 in the fixed pin track 1211-2, so that the connecting part 1211 drives the clamping part 1212 to open and close along the direction restricted by the fixed pin track 1211-2.

[0173] In the above embodiments, the moving pin hole 1211-1 is located near the end point of the connecting part 1211 (i.e., the farthest end of the connecting part 1211 away from the clamping part 1212), and the fixed pin track 1211-2 is located near the tail end of the end point. In conjunction with the arrangement of the support member 112, the moving pin 115 and the fixed pin 114, the clamping member 121 is subjected to as little interference as possible during the movement. The envelope surface of the position traversed by the connecting part 1211 supports the clamping part 1212 at a larger opening angle with the smallest possible range. In addition, this structural design is more compact and effectively utilizes the space of the connecting part 1211, so that the valve clamping device 100 has a smaller overall size, while supporting a larger opening angle range of the valve clamping device 100.

[0174] In one implementation, the fixed pin track 1211-2 adopts a two-section design, wherein the first section supports the valve clamping device 100 from a closed state to an open state when capturing the valve leaflets (e.g., Figure 5 and Figure 11 As shown, during the change of the clamping member 121 (referred to as the first open state), the movement trajectory of the connecting part 1211 of the clamping member 121 changes, and the second segment supports the valve clamping device 100 from the failure to capture the valve leaflet (i.e., the first open state) to the inverted state (as shown in the figure). Figure 7As shown, the movement trajectory of the connecting part 1211 of the clamping member 121 changes during the change process. That is, during the change of the valve clamping device 100 from the closed state to the first open state, the fixing pin 114 is located at different positions in the first segment, and during the change of the valve clamping device 100 from the first open state to the inverted state, the fixing pin 114 is located at different positions in the second segment. The second segment, relative to the first segment, allows the connecting part 1211 to support the clamping member 121 at a faster opening speed with a shorter movement trajectory, thus providing better operability.

[0175] In one implementation, the fixing pin track 1211-2 adopts an arc-shaped track design to reduce the resistance force of the fixing pin 114 on the connecting part 1211 when it moves along the opening, making its movement smoother. In this case, the first segment can be the first arc-shaped segment, and the second segment can be the second arc-shaped segment. Please continue to refer to... Figure 32 and Figure 36 The fixed pin track 1211-2 includes a first arc segment L1 and a second arc segment L2. The first arc segment L1 is close to the first end E1, and the second arc segment L2 is close to the second end E2. The arc of the second arc segment L2 is greater than that of the first arc segment L1. In other words, the radius of the first arc segment L1 is larger than that of the second arc segment L2, making the curvature of the second arc segment L2 more obvious. In this way, the transmission component can drive the clamping component 121 to move a wider range with a shorter axial movement distance, so that the valve clamping device 100 has a larger opening angle.

[0176] Furthermore, the radial cross-sectional dimension of the connecting portion 1211 of the clamping member 121 gradually decreases from the second end E2 to the first end E1. For example... Figure 32 and Figure 36 As shown, the radial dimension of the connecting portion 1211 gradually decreases away from the clamping portion 1212, making it more suitable for the layout of the fixing pin rails 1211-2 and supporting a more compact structural design for the clamping member 121. This embodiment shows an irregular fan-shaped (or fan-like) structure with a fan-shaped end and an arc-shaped design on the outer edge of the opening away from the support member 112, to reduce resistance during valve clamping device delivery, making delivery easier and reducing potential harm or discomfort to the patient. In other embodiments, other shapes can also be supported, such as an edge design with the same variation trend as the fixing pin rails 1211-2 on the side facing the opening.

[0177] In another implementation, the fixed pin rail 1211-2 may not employ an arc-shaped rail design. Please refer to the following references. Figure 34It adopts an intersecting straight segment design. The fixed pin track 1211-2 includes a first straight segment L1' and a second straight segment L2'. The first straight segment L1' is close to the first end E1, and the second straight segment L2' is close to the second end E2. The slope of the second straight segment L2' is greater than the slope of the first straight segment L1'. In this way, the transmission component can drive the clamping component 121 to move a wider range with a shorter axial movement distance, so that the valve clamping device 100 has a larger opening angle.

[0178] Please continue to refer to this. Figures 35-37 The clamping portion 1212 of the clamping member 121 is further provided with a rolled edge structure 1212-4. The bending direction of the rolled edge structure 1212-4 is opposite to the clamping direction, so that when the clamping is engaged, the clamping member 121 is more closely attached to the main body 110 (e.g., the attachment 113), further improving the clamping effect of the valve clamping device. This rolled edge structure 1212-4 can also be called a flange, and is provided on all or part of the edge of the clamping portion 1212, such as... Figures 35-37 As shown, in one implementation, it is set at the side edge and end edge with the greatest width.

[0179] As can be seen, the independent design of the two-section structure of the fixed pin track 1211-2 can also support the valve clamping device to achieve a larger opening angle with a more compact structure. Therefore, under this structural design, the position of the moving pin hole 1211-1 can be located in other places, for example, further away from the first end E1 compared to the above embodiment. However, the position design in the above embodiment has a more compact structure and lower design requirements for the connecting part 1211 within the internal space of the support member 112, because this position results in less interference at the bottom end of the connecting part 1211.

[0180] The structural design in the above embodiments enables the valve clamping device 100 to support a larger opening angle range with a more compact structure. For example, the opening and closing movement of the clamping members 121 causes the included angle between the clamping members 121 toward the proximal end to vary between 0° and 300°.

[0181] The connection between the clamping part 1212 and the connecting part 1211 can be a direct connection or a connection through other parts. For example, the clamping part 1212 can be connected to the connecting part 1211 through the support part 1213. This design can make the gripping member 122 and the clamping member 121 fit more closely when they dock, thereby improving the clamping performance of the valve clamping device. This will be described in subsequent embodiments.

[0182] The structure of support member 112 is described below with reference to the accompanying drawings:

[0183] Please continue to refer to this. Figure 31 and in conjunction with references Figure 38 and Figure 39These are three-dimensional structural schematic diagrams of different support members provided in the embodiments of this application, wherein, Figure 39 A capture element 122 is mounted on the top. The support member 112 includes a first support wall 1121 and a second support wall 1122 disposed opposite to each other, forming an accommodating space S between the opposing surfaces of the first support wall 1121 and the second support wall 1122, and having an opening between them. The support member 112 also includes a proximal connector 1123 for connecting the first support wall 1121 and the second support wall 1122, i.e., the first support wall 1121 and the second support wall 1122 are disposed opposite to each other on the proximal connector 1123. A fixing pin 114 is connected between the first support wall 1121 and the second support wall 1122; the distal end of the transmission member passes through the proximal connector 1123 and is located within the accommodating space S, and the axial movement of the transmission member changes its length within the accommodating space S.

[0184] Furthermore, a motion pin track 1125 is provided on the first support wall 1121 and / or the second support wall 1122, extending from the proximal end to the distal end of the support wall; the motion pin 115 follows the axial movement of the transmission component and moves axially along the motion pin track 1125. When a motion pin track 1125 is provided on one support wall, the motion pin 115 is restricted in its movement trajectory by the motion pin track 1125 and the transmission component, that is, the motion pin 115 follows the axial movement of the transmission component and moves axially along the motion pin track 1125; when motion pin tracks 1125 are provided on both support walls, the two motion pin tracks 1125 are parallel to each other, and the motion pin 115 follows the axial movement of the transmission component and moves axially along the two motion pin tracks 1125. This provides better restriction on the movement trajectory of the motion pin 115 and improves the stability of the valve clamping device.

[0185] The motion pin track 1125 can be provided in the form of a hollowed-out section on the support wall; or it can be provided in the form of a track groove on the inner wall of the support wall, which is a groove on the inner wall but does not penetrate the entire support wall; or it can be provided in the form of a track component on the inner wall of the support wall. The hollowed-out track can reduce the weight of the support component 112 and has the advantages of simple processing and high stability.

[0186] The fixing pin 114 is installed between the first support wall 1121 and the second support wall 1122, but its installation method is not limited; it can be pinned, welded, or snap-fitted, etc. For example, Figure 38 and Figure 39 As shown, the first support wall 1121 and the second support wall 1122 are provided with pin holes 1126 for installing fixing pins 114.

[0187] Furthermore, the support member 112 also includes a distal connector 1124, and the first support wall 1121 and the second support wall 1122 are respectively disposed on the distal connector 1124, thereby improving the stability of the support walls and further improving the stability of the valve clamping device. Optionally, as Figure 40 As shown, the inner wall of the distal connector 1124 has a limiting groove 1124-1, and the axial movement of the distal end of the transmission member 111' in the accommodating space S is limited within the limiting groove 1124-1. Thus, when the distal end of the transmission member 111' moves to the distal end of the support member 112, it can be accommodated within the limiting groove 1124-1. At this time, the valve clamping device 100 is in a closed state, that is, when the clamping member 121 is clamped onto the main body 110, the distal end of the transmission member 111' is accommodated within the limiting groove 1124-1. Since the limiting groove 1124-1 can restrict the radial sway of the transmission member 111', the stability of the valve clamping device 100 in the closed state can be further improved, thus enhancing the repair effect.

[0188] This embodiment of the application can limit the movement not only at the distal end of the support member 112, but also at the proximal end. In this case, the transmission member 111' passes through the proximal connector 1123 through the limiting channel 1123-1. That is, the proximal connector 1123 of the support member 112 has a limiting channel 1123-1, the transmission member 111' passes through the limiting channel, and its radial movement is limited within the limiting channel 1123-1. The size of the limiting channel 1123-1 is just enough for the transmission member 111' to pass through, which can limit the radial sway of the transmission member 111', making the axial movement of the transmission member 111' more stable, and thus the transmission more stable, which can effectively improve the stability of the valve clamping device 100 during use.

[0189] This application does not limit the cross-sectional shape of the support wall of the support member 112. In one implementation, the support wall has a subtractive material design towards the proximal and distal ends, that is, the cross-sectional dimensions of the proximal and distal ends are smaller than the cross-sectional dimensions of the middle section. However, the cross-sectional dimensions of the proximal and distal ends can be the same or different (e.g., Figure 41 (As shown). Among them, Figure 38 , Figure 39 and Figure 41 Different embodiments of the support member 112 are given respectively.

[0190] The capture device is described below with reference to the attached diagram:

[0191] like Figures 42 to 46As shown, the capturing element 122 includes a mounting portion 1221, a bending portion 1222, and a capturing portion 1223. The bending portion 1222 connects the mounting portion 1221 and the capturing portion 1223, such that the capturing portion 1223 has a first angle relative to the main body 110 (or the axial direction) in its natural state. This first angle is greater than or equal to 60 degrees and less than or equal to 90 degrees, or the angle between the capturing elements 122 is within the range of 120 degrees to 180 degrees (including the boundary value). Thus, in its natural state, it has a shape suitable for capturing lobes. After the capturing element 122 is released, it will quickly fit into the clamping element 121, which is beneficial for capturing lobes.

[0192] In one implementation, the capturing member 122 is provided with a connecting hole 1225 for connecting a control mechanism that controls the capturing member 122, for example, Figure 37 As shown, the control mechanism controls the state of the grabbing member 122 through the control line 216. The control line 216 passes through the connection hole 1225. When the grabbing member 122 does not capture the petals, the control line 216 is tightened and the grabbing member 122 is attached to the main body 110. When the grabbing member 122 captures the petals, the control line 216 is released, and the grabbing member 122 quickly opens towards the clamping member 121 without external force control (in its natural state) and docks with the clamping member 121 to capture the petals.

[0193] Furthermore, the bent portion 1222 or the entirety of the grasping member 122 is made of an elastic material, which can be an elastic alloy, such as a nickel-titanium alloy. This elastic material facilitates repeated opening and closing movements of the grasping member 122, and because the grasping member 122 has a first angle with the main body 110 in its natural state, the grasping member 122 can quickly open towards the clamping member 121 to capture the petals. The grasping member 122 can be integrally molded from an elastic material to reduce production costs; alternatively, the bent portion 1222 of the grasping member 122 can be made of an elastic material, while all or part of the other parts (e.g., the mounting portion) can be made of a rigid material to improve connection rigidity.

[0194] Furthermore, the capturing part 1223 is provided with multiple friction elements 1224. The clamping part 121 is provided with a perforation 1212-3, such as... Figure 31 As shown, when the grabbing member 122 and the clamping member 121 are docked, the friction element 1224 extends into the hollow 1212-3. In this way, not only can the weight of the clamping member 121 be reduced, but the clamping effect can also be improved, making the valve clamping device 100 easier to control during operation and having a better clamping effect.

[0195] In one implementation, at least one cutout 1222-1 is provided on the bent portion 1222 of the grabbing member 122 to reduce the material of the bent portion 1222. Thus, when the grabbing member 122 and the clamping member 121 cooperate to capture the petals and perform opening and closing movements, the bent portion 1222 has sufficient toughness and low stiffness.

[0196] Optionally, the support member 112 can further support the installation of the capture member 122, for example, it can support the capture member 122 to be installed on the side end face or in the accommodating space S, which will be described in detail in the following embodiments.

[0197] In some respects, the stability of the valve clamping device is of great significance to the effect of valve repair. In view of this, some embodiments of this application provide a valve clamping device and a valve repair system that have better stability when used by the operator, thereby improving the effect of edge-to-edge repair.

[0198] In the embodiments of this application, a support member is provided at the distal end of the valve clamping device to support the clamping body. The support member has an internal accommodating space with an external opening, allowing the connecting portion of the clamping member to extend into the accommodating space. Changes in its position within the accommodating space cause the clamping portion to open and close relative to the main body. Furthermore, the grasping member includes an mounting portion, a grasping portion, and a bent portion disposed between the mounting portion and the grasping portion. The mounting portion is fixedly disposed on the support member to securely mount the grasping member onto the support member. The bent portion allows the grasping portion to open relative to the main body in its natural state (i.e., having a first included angle). In this valve clamping device structure, the connecting portion of the clamping member is movably disposed within the support member, and the mounting portion of the grasping member is fixed to the support member. Thus, when the clamping member is driven to open and close, the state of the grasping member is more stable and it does not move with the driving force, thereby improving the stability of the valve clamping device and achieving a better repair effect.

[0199] The following description is in conjunction with the accompanying drawings. Please refer to them. Figure 47 This is a three-dimensional structural schematic diagram of another valve clamping device provided in an embodiment of this application. The valve clamping device 100 includes a main body 110 and a clamping body 120. A support member 112 is provided at the distal end of the main body 110 for supporting or mounting the clamping body 120. The clamping body 120 includes clamping elements 121 and grasping elements 122. There are multiple clamping bodies 120, i.e., two or more, disposed around the periphery of the main body 110 and capable of opening and closing relative to the main body 110. For ease of explanation, this description uses two clamping bodies 120 as an example; the implementation of more clamping bodies is similar. Furthermore, Figure 31 The embodiments can also be designed with a structure similar to this embodiment.

[0200] Please refer to the reference. Figure 48 , it is Figure 47 The illustrated embodiment shows a three-dimensional structural view of the support member equipped with the capture device from another perspective. This is to clearly demonstrate the structure of the support member. Figure 48 Only the capture and support components were retained. (For example...) Figure 47 and Figure 48 As shown, the support member 112 has a first opening side M1 and a second opening side M2, and the interior of the support member 112 has an accommodating space S. The first opening side M1 has a first opening O1 that allows the accommodating space S to be exposed to the outside, and the second opening side M2 ​​has a second opening O2 that allows the accommodating space S to be exposed to the outside.

[0201] Please continue to refer to this. Figure 47 The clamping member 121 includes a connecting portion 1211 and a clamping portion 1212. The connecting portion 1211 extends into the accommodating space S through the opening of the support member 112 and is installed in the accommodating space S. The position change of the connecting portion 1211 in the accommodating space S causes the clamping portion 1212 to open and close relative to the main body 110. For the sake of distinction, the clamping member 121 in which the connecting portion 1211 extends into the accommodating space S through the first opening O1 of the support member 112 is called the first clamping member, and the clamping member 121 in which the connecting portion 1211 extends into the accommodating space S through the first opening O2 of the support member 112 is called the second clamping member; that is, the clamping member 121 on the same side as the first opening side M1 of the support member 112 is called the first clamping member, and the clamping member 121 on the same side as the second opening side M2 ​​of the support member 112 is called the second clamping member.

[0202] Please refer to the reference. Figure 48 The catching component 122 includes a mounting portion 1221, a bending portion 1222, and a catching portion 1223. The mounting portion 1221 is fixedly disposed on the support member 112, that is, the mounting portion 1221 is used to fix the catching component 122 onto the support member 112. The bending portion 1222 connects the mounting portion 1221 and the catching portion 1223, such that the catching portion 1223 has a first included angle relative to the main body 110 in its natural state. For the sake of distinction, the catching component located on the same side of the main body as the first clamping component is called the first catching component, and the catching component located on the same side of the main body as the second clamping component is called the second catching component. The mounting portion of the first catching component is called the first mounting portion, the bending portion is called the first bending portion, and the catching portion is called the first catching portion; the mounting portion of the second catching component is called the second mounting portion, the bending portion is called the second bending portion, and the catching portion is called the second catching portion.

[0203] As can be seen, in the valve clamping device of the above embodiments, the connecting part of the clamping member is movably installed in the accommodating space within the support member, and the mounting part of the grasping member is fixed on the support member. It is evident that the support member provides the clamping member with an installation space and a driving space for the connecting part during the opening and closing movement, and provides a fixed installation position for the grasping member. Thus, when the clamping member is driven to open and close, the state of the grasping member is more stable and will not move with the driving force, thereby improving the stability of the valve clamping device and providing a better repair effect during use.

[0204] When the capturing member 122 is installed, the capturing part 1223 can be positioned between the main body 110 and the clamping member 121 on the same side. Thus, after the clamping member 121 and the capturing member 122 capture the petals, when the clamping member 121 closes relative to the main body 110, it can cause the capturing member 122 on the same side to close together. Furthermore, when the clamping member 121 is clamped onto the main body 110, the capturing part 1223 of the capturing member 122 on the same side is held between the main body 110 and the clamping member 121.

[0205] The structure of the capture device is described below with reference to the attached diagram:

[0206] Please refer to Figures 42-46 ,in, Figures 42-45 The integrated capture mechanism structure is shown; Figure 46 A separately configured grasping member structure is shown. The grasping member 122 includes a mounting portion 1221, a bending portion 1222, and a grasping portion 1223. The mounting portion 1221 is used to fix the grasping member 122 to the support member 112. The bending portion 1222 connects the mounting portion 1221 and the grasping portion 1223, such that the grasping portion 1223 has a first angle relative to the main body 110 (or axis) in its natural state. This first angle is greater than or equal to 60 degrees and less than or equal to 90 degrees, or the angle between the grasping members 122 is within the range of 120 degrees to 180 degrees (including boundary values). Thus, in its natural state, it has a shape suitable for grasping lobes. After the grasping member 122 is released, it will quickly fit into the clamping member 121, which is beneficial for grasping lobes.

[0207] In one implementation, the capturing member 122 is provided with a connecting hole 1225 for connecting a control mechanism that controls the capturing member 122, for example, Figure 37 As shown, the control mechanism controls the state of the grabbing member 122 through the control line 216. The control line 216 passes through the connection hole 1225. When the grabbing member 122 does not capture the petals, the control line 216 is tightened and the grabbing member 122 is attached to the main body 110. When the grabbing member 122 captures the petals, the control line 216 is released, and the grabbing member 122 quickly opens towards the clamping member 121 without external force control (in its natural state) and docks with the clamping member 121 to capture the petals.

[0208] Furthermore, the bent portion 1222 or the entirety of the grasping member 122 is made of an elastic material, which can be an elastic alloy, such as a nickel-titanium alloy. This elastic material facilitates repeated opening and closing movements of the grasping member 122, and because the grasping member 122 has a first angle with the main body 110 in its natural state, the grasping member 122 can quickly open towards the clamping member 121 to capture the petals. The grasping member 122 can be integrally molded from an elastic material to reduce production costs; alternatively, the bent portion 1222 of the grasping member 122 can be made of an elastic material, while all or part of the other parts (e.g., the mounting portion) can be made of a rigid material to improve connection rigidity.

[0209] Furthermore, the capturing part 1223 is provided with multiple friction elements 1224. The clamping part 121 is provided with a perforation 1212-3, such as... Figure 31 and Figure 47 As shown, when the grabbing member 122 and the clamping member 121 are docked, the friction element 1224 extends into the hollow 1212-3. In this way, not only can the weight of the clamping member 121 be reduced, but the clamping effect can also be improved, making the valve clamping device 100 easier to control during operation and having a better clamping effect.

[0210] In one implementation, such as Figure 42 and Figure 44 As shown, at least one hollow 1222-1 is provided on the bent portion 1222 of the capturing member 122 to reduce the material of the bent portion 1222. In this way, when the capturing member 122 and the clamping member 121 cooperate to capture the petals and perform opening and closing movements, the bent portion 1222 has sufficient toughness and low rigidity.

[0211] In one implementation, such as Figure 42 and Figure 44 As shown, the mounting portion 1221 of the grasping member 122 is integrally formed as a common mounting portion and has a through hole 1221-1 for the transmission member that drives the clamping member 121 to open and close to pass through. In a separately configured grasping member structure, the through hole can be disregarded, and the movement of the transmission member will not affect the grasping member; therefore, the stability of the valve clamping device is better. This application does not limit the shape of the common mounting portion of the grasping member 122; it can be a regular shape or an irregular shape. Figure 42 and Figure 44 The diagram shows an approximately square structure with rounded notches at the four corners to facilitate engagement with the support member 112. In other embodiments, the mounting portion may also be other polygonal or irregular shapes.

[0212] In some embodiments of this application, when the clamping member 121 and the grasping member 122 are docked, the side end face B2 of the grasping member 122 contacts the adjacent side end face B1 of the clamping member 121 (e.g., Figure 48 , Figures 32-35As shown in the diagram, this design not only results in a smaller gap and better fit between the grasping member 122 and the clamping member 121 in the docking direction, allowing for better contact between the clamping member 121 and the grasping member 122 on the same side, but also enables a more compact structural design in the direction perpendicular to the docking direction, achieving a smaller size design for the valve clamping device 100. Specifically, when the contact portions of the adjacent side end faces of the grasping member 122 and the clamping member 121 are matched, the valve clamping device 100 has a compact structure, better clamping performance, and superior overall structural stability.

[0213] By employing a separate arrangement of the capture components on different sides, this separation facilitates the fitting design of the capture and clamping components on the same side. A simple installation position design can resolve the fitting issue between the capture and clamping components, providing clearance between them and reducing the overlap between the clamping and capture components in the docking direction (i.e., the opening and closing direction). Thus, when the capturing part of the capture component and the clamping part of the clamping component dock together (e.g., ... Figure 31 and Figure 47 As shown, the grabbing component and the clamping component have a smaller gap and better fit in the docking direction, which makes the clamping component and the grabbing component on the same side fit better, thus having better clamping performance.

[0214] Please continue to refer to this. Figures 47-48 The grabbing elements 122 are separately disposed on different opening sides of the support member 112. For example, the first grabbing element and the second grabbing element are separately disposed on the first opening side M1 and the second opening side M2. This arrangement provides better fit between the grabbing elements 122 and the clamping element 121 during docking and provides a simpler space for the accommodating space S, facilitating changes in the position of the connecting portion 1211 of the clamping element 121. This helps to improve the overall size of the valve clamping device 100 and supports a wider range of opening angle changes.

[0215] Please refer to the reference. Figure 49 , it is Figure 47 A three-dimensional structural view of the support member from another angle in the illustrated embodiment. (See diagram below.) Figures 47-49As shown, the first opening side 1121 includes side end faces M1-1 and M1-2 located on both sides of the first opening O1 (referred to as the first side end face and the second side end face, respectively, for distinction); similarly, the second opening side 1122 includes side end faces M2-1 and M2-2 located on both sides of the second opening O2 (referred to as the third side end face and the fourth side end face, respectively, for distinction), with side end faces M1-1 and M2-1 facing each other, and side end faces M1-2 and M2-2 facing each other; wherein, the first grasping member is mounted on the first side end face via its mounting part, and the second grasping member is mounted on the fourth side end face via its mounting part. It can be seen that in this structure, the grasping members are not axially symmetrically mounted on both sides of the support member, but rather diagonally mounted, making the entire structure of the valve clamping device more balanced and stable. This is more conducive to the delivery and operation of the valve clamping device, resulting in better repair effects during use.

[0216] In one implementation, the thickness of the side end face where the grabbing element is installed can be increased. This increased thickness not only better accommodates the mounting portion 1221 of the grabbing element 122, but also provides support for the clamping element 121 within the accommodating space S. Therefore, the increased thickness better supports the clamping element 121 and improves the overall stability of the valve clamping device 100. For example, the side end face M1-1 where the first grabbing element is installed and the side end face M2-2 where the second grabbing element is installed have a first thickness, and the side end faces M1-2 and M2-1 have a second thickness, with the first thickness being greater than the second thickness.

[0217] The mounting portion 1221 of the capture element 122 can be mounted on the side end face by means of pin connection, snap-fit, welding, or interference fit, etc., and this application is not limited to the mounting method of the capture element 122. In one implementation, such as Figure 48 and Figure 49As shown, receiving grooves 1121-1 and 1122-1 are respectively provided on side end faces M1-1 and M2-2. The mounting part 1221 of the capturing member 122 is disposed in the receiving groove and matches the receiving groove. For example, the mounting part of the first capturing member is disposed in the receiving groove 1121-1 of side end face M1-1 and matches the receiving groove 1121-1; the mounting part of the second capturing member is disposed in the receiving groove 1122-1 of side end face M2-2 and matches the receiving groove 1122-1. In this way, the mounting part 1221 of the capturing member 122 is matched and installed in the receiving groove, making its installation more stable. Furthermore, the thickness of the mounting portion 1221 matches the depth of the receiving groove, making the mounting portion 1221 flush with the outer edge of the side end face of the support member 112. This gives the support member 112 a smoother outer edge, allowing the valve clamping device 100 to enter the patient's body more smoothly, effectively reducing harm to the patient or alleviating discomfort. In one implementation, the receiving groove has a pin hole (pin hole 1121-2 in the receiving groove 1121-1 is shown in the figure), and the mounting portion 1221 of the grasping member 122 also has a pin hole 1221-1, so as to pin the mounting portion 1221 of the grasping member 122 into the receiving groove.

[0218] Please continue to refer to this. Figure 49 The support member 112 includes a main end face and a side end face. The inner surfaces of the main end face are arranged opposite each other, forming an accommodating space S for the support member 112. The outer surface is parallel to the inner surface. The side end face intersects the main end face (it can intersect perpendicularly or not perpendicularly), and the side end face is used to mount the grabbing element 122. Figure 49 As shown, the support member 112 includes a first support wall 1121 and a second support wall 1122 disposed opposite to each other, forming an accommodating space S between the first support wall 1121 and the second support wall 1122. The first support wall 1121 has a main end face and a side end face, and the second support wall 1122 has a main end face and a side end face, wherein side end face M1-1 and side end face M2-1 are the side end faces of the first support wall 1121, and side end face M1-2 and side end face M2-2 are the side end faces of the second support wall 1122. In this embodiment, two clamping bodies and two support walls are used as an example. When there are more clamping bodies, more support walls can be provided, which are disposed on the peripheral side of the far end of the main body. The inner surfaces are arranged opposite to each other to form an accommodating space. An opening is reserved between adjacent support walls to facilitate the insertion and installation of one end of the clamping member of the clamping body. A grasping member is installed on the side end face adjacent to the opening to cooperate with the clamping member and capture the petals.

[0219] Furthermore, the side end faces of the support walls of the support member 112 (e.g., side end face M1-1 of the first support wall 1121 and side end face M2-2 of the second support wall M2) are thickened to accommodate the grasping member 122. For example, the side end faces M1-1 of the first support wall 1121 and M2-2 of the second support wall 1122 have a first thickness greater than the width of the mounting portion 1221 of the grasping member 122. This facilitates the installation of the grasping member 122. As described above, receiving grooves can be provided in the side end faces M1-1 and M2-2 to facilitate a more stable installation of the mounting portion 1221 of the grasping member 122 within the receiving grooves.

[0220] As described above, such as Figure 49 As shown, the side end face M1-1 of the first support wall 1121 of the support member 112 has a thicker thickness than other parts, that is, its thickness is greater than the thickness of other parts of the first support wall 1121 and the thickness of the side end face M2-1 of the second support wall 1122. This thickened design structure can not only better accommodate the grasping member 122, but also the support member 112 provides support for the installation of the clamping member 121 within the accommodating space S. Therefore, the thickened support wall can better support the clamping member 121 and improve the overall stability of the valve clamping device 100. Similarly, the second support wall 1122 can be made with the same structure as the first support wall 1121, that is, with a thicker part, thus better supporting the clamping member 121 and further improving the overall stability of the valve clamping device 100. In another implementation, the thickness of other parts of the first support wall 1121 other than the side end face M1-1 can also be made to be the same as the thickness of the side end face M1-1, thus further improving the overall stability of the valve clamping device 100. However, considering the balance between the overall size and stability of the valve clamping device 100, Figure 49 The structure shown has good stability and optimal dimensional balance.

[0221] In another implementation, such as Figure 50 As shown, the valve clamping device 100 includes an integrally formed grasping member 122. The mounting portions 1221 of different grasping members 122 are integrally formed into a common mounting portion and fixedly disposed within the accommodating space of the support member 112. The installation method of the grasping member 122 within the support member 112 is not limited; it can be achieved through pinning, snap-fitting, welding, or interference fit, etc. For example, similar... Figure 42 and Figure 44The mounting portion 1221 may have multiple recessed positions on its periphery, which are engaged with the near end of the support member 112. These engagement positions can be welded. Optionally, the inner wall of the support member 112 may have multiple grooves at the engagement positions of the grabbing member 122, allowing the protruding ends of the grabbing member 122 to be inserted. That is, the mounting portion 1221 of the grabbing member 122 includes multiple protruding ends, and the inner wall of the support member 112 has grooves corresponding to these protruding ends, with the protruding ends embedded in the grooves, making the connection of the grabbing member more secure. Optionally, a through hole may be provided on the mounting portion 1221 for the transmission component to pass through; this mounting method is easier to manufacture and requires fewer steps.

[0222] Please continue to refer to this. Figures 32-36 In one implementation, the clamping portion 1212 of the clamping member 121 includes a body 1212-1 and clamping leaves 1212-2, with the clamping leaves 1212-2 symmetrically arranged on both sides of the body 1212-1. The clamping member 121 also includes a support portion 1213 located between the clamping portion 1212 and the connecting portion 1211. The support portion 1213 is located on the side of the body 1212-1 away from the grasping member and extends to the connecting portion 1211. Specifically, the connecting portion 1211 and the support portion 1213 are not located at the center of the body 1212-1, but are located on the side away from the grasping member 122, such that the side B1 of the connecting portion 1211 and the side B2 of the grasping member 122 (e.g., ...) are close to the grasping member 122. Figure 48 (As shown) contact, to achieve a compact design.

[0223] Optionally, such as Figures 32-36 As shown, the clamping part 1212 of the clamping member 121 includes at least one hollow part 1212-3 in its body 1212-1. The grasping part 1223 of the grasping member 121 is provided with multiple friction elements 1224. When the grasping member 122 and the clamping member 121 are engaged, the friction elements 1224 extend into the hollow part 1212-3. This not only reduces the weight of the grasping member 121 but also improves the clamping effect, making the valve clamping device 100 easier to control during operation and providing a better clamping effect.

[0224] Please refer to Figure 46In some embodiments of this application, the bending portion 1222 of the grasping member 122 has a first bend where it connects to the mounting portion 1221, and a second bend where it connects to the grasping portion 1223, and the width (or cross-sectional dimension) of the first bend is smaller than the width of the second bend. Thus, the bending portion 1222 has a bent shape with subtractive material, and when the grasping member 122 and the clamping member 121 cooperate to capture the leaflets and perform opening and closing movements, the bending portion 1222 has sufficient toughness and low stiffness. In one implementation, subtraction can be performed at the first bend, with a continuous or discontinuous increase in width towards the second bend; for example, there is a width decreasing segment between the second bend and the first bend. Taking two capturing components 122 as an example, for the sake of distinction, the first and second bends of the first capturing component will still be referred to as the first bend and the second bend, while the first and second bends of the second capturing component will be referred to as the third bend and the fourth bend. That is, the first bend of the first capturing component has a first bend where it connects to the first mounting part, and a second bend where it connects to the first capturing part, and the width of the first bend is smaller than the width of the second bend; and the second bend has a third bend where it connects to the second mounting part, and a fourth bend where it connects to the second capturing part, and the width of the third bend is smaller than the width of the fourth bend. In one implementation, the first bend includes a width-decreasing segment from the second bend to the first bend, and the second bend includes a width-decreasing segment from the fourth bend to the third bend.

[0225] Similar to the embodiments above, in some embodiments of this application, at least one hollow section can be provided on the bent portion to achieve another form of material reduction. Thus, when the grasping member 122 and the clamping member 121 cooperate to capture the petals and perform opening and closing movements, the bent portion 1222 has sufficient toughness and low stiffness. These two material reduction methods can be used independently or in combination.

[0226] Furthermore, the friction elements 1224 of the grasping member 122 can be configured in multiple groups. For example, in one implementation, 1-4 groups are configured, with each group having 2 friction elements, thus reducing the difficulty of capturing the leaflets. In one implementation, such as... Figures 42-46As shown, the gripping part 1223 of the gripping member 122 includes a first support section 1223-1 and a second support section 1223-2. The first support section 1223-1 is provided with friction elements 1224 facing the clamping member 121. The second support section 1223-2 connects the bent part 1222 and the first support section 1223-1. The first support section 1223-1 is provided with multiple sets of friction elements 1224. The first support section 1223-1 has a multi-segment structure, with each segment decreasing in size towards the direction away from the second support section 1223-2. Each set of friction elements 1224 is located at the maximum size position of each segment, and the connection size between segments is the minimum size. Thus, the triangular design structure of each segment can more stably support the friction elements 1224, improving the clamping performance of the valve clamping device. The final segment is designed with an arc shape, which provides a smooth outer edge, allowing the valve clamping device 100 to enter the patient's body more smoothly. This effectively reduces harm to the patient or alleviates discomfort. This application does not limit the number of friction elements 1224; only four sets are used as an example here.

[0227] Taking two capturing components 122 as an example, for the sake of distinction, the first and second support sections of the first capturing component will still be referred to as the first support section and the second support section, and the first and second support sections of the second capturing component will be referred to as the third support section and the fourth support section. Thus, the first capturing part includes the first and second support sections, with a friction element facing the first clamping component on the first support section, and the second support section connecting the first bending portion and the first support section; and the second capturing part includes the third and fourth support sections, with a friction element facing the second clamping component on the third support section, and the fourth support section connecting the second bending portion and the third support section. In one implementation, a first support segment is provided with multiple sets of friction elements. The first support segment has a multi-segment structure, with the size of each segment decreasing in the direction away from the second support segment. Each set of friction elements is located at the maximum size position of each segment, and the connection size between segments is the minimum size. A third support segment is provided with multiple sets of friction elements. The third support segment has a multi-segment structure, with the size of each segment decreasing in the direction away from the fourth support segment. Each set of friction elements is located at the maximum size position of each segment, and the connection size between segments is the minimum size.

[0228] The above embodiments of this application provide an indirect hinge form, which makes the movement of the clamping member 121 more stable.

[0229] For example, such as Figures 32-36 As shown, the clamping member 121 includes a clamping portion 1212 and a connecting portion 1211. The clamping portion 1212 and the connecting portion 1211 are connected, and the connecting portion 1211 is hinged to the second connecting rod 1112. The connecting portion 1211 and the clamping portion 1212 are connected by a support portion 1213. Figure 34In the illustrated embodiment, the support portion 1213 has a larger cross-sectional area than the connecting portion 1211, thereby providing a certain connection strength between the connecting portion 1211 and the clamping portion 1212, allowing the clamping portion 1212 to more stably clamp the leaflet. The support portion 1213 also allows the clamping member 121 to fit more closely to the grasping member 122. Optionally, an obtuse angle is formed between the connecting portion 1211 and the support portion 1213, which allows the clamping portion 1212 to fit more closely to the grasping member 122, resulting in better capture.

[0230] In one implementation, the clamping member 121 can be integrally formed, which can improve the connection strength between different parts, thereby improving the structural strength of the clamping member 121 and further improving the stability of the valve clamping device 100 during operation.

[0231] Similar to the above embodiments, the connecting portion 1211 of the clamping member 121 has a moving pin hole 1211-1 and a fixed pin track 1211-2. The support member 112 has a moving pin track 1125. The main body 110 of the valve clamping device 100 also includes a moving pin 115 and a fixed pin 114. The moving pin 115 passes through the moving pin hole 1125 and the distal end of the second link 1112, and moves along the moving pin track 1125 following the axial movement of the second link 1112; the fixed pin 114 passes through the fixed pin track 1211-2 and is connected to the support member 112.

[0232] Taking a pair of clamping parts 121 as an example, the fixing pin 114 passes through the fixing pin track 1211-2 of the connecting part 1211 of a single clamping part 121 to connect the connecting part 1211 to the support member 112. The moving pin 115 passes through the moving pin hole 1211-1 of the connecting part 1211 of the pair of clamping parts 1211 to connect the connecting part 1211 to the support member 112. One end of the moving pin 115 is slidably located in the moving pin track 1125, which is axially located in the first support wall 1121 of the support member 112 and passes through the first support wall 1121. The other end is slidably connected to the second support wall 1122 of the support member 112. Alternatively, the moving pin track 1125 is axially located in the two support walls of the support member 112 and passes through the two support walls, so that the moving pin 115 slides axially along the moving pin track 1125.

[0233] In this embodiment, by setting the moving pin track 1125 and the fixed pin track 1211-2, the opening and closing trajectory of the clamping member 121 can be limited, further improving the stability of the valve clamping device 100 during operation.

[0234] The operation of the above-mentioned hinge structure is described below in conjunction with the state of the valve clamping device 100. When the valve clamping device 100 is in the closed state, as follows: Figure 4 and Figure 15As shown, the moving pin 115 is located at the far end of the moving pin track 1125, and the fixed pin 114 passes through the fixed pin track 1211-2 and is positioned at a certain distance from both ends of the fixed pin track 1211-2. When the second connecting rod 1112 moves axially towards the near end, the moving pin 115 moves along the moving pin track 1125 towards the near end, the clamping member 121 opens, and gradually moves away from the main body 110. Figure 5 and Figure 16 The diagram shows that when the clamping member 121 opens to a certain angle, the moving pin 115 moves to a position in the moving pin track 1125. At this point, if the leaflet is captured, the second link 1112 moves axially towards the distal end, and the moving pin 115 follows the second link 1112 along the moving pin track 1125 towards the distal end. The clamping member 121 gradually closes, and once the moving pin 115 has moved to the distal end of the moving pin track 1125, the valve clamping device 100 returns to the closed state. If leaflet capture fails, the second link 1112 moves axially towards the proximal end, and the moving pin 115 follows the second link 1112 along the moving pin track 1125 towards the proximal end. The clamping member 121 further opens, as... Figure 7 and Figure 17 As shown, when the moving pin 115 is located at the proximal end of the moving pin track 1125, the valve clamping device 100 is in an inverted state.

[0235] Similar to the embodiments described above, in some embodiments of this application, the proximal end of the support member 112 can limit the second connecting rod 1112, and / or the distal end of the support member 112 can limit the second connecting rod 1112. For example, the proximal end of the support member 112 is provided with a channel 1123-1, the size of which is just large enough for the second connecting rod 1112 to pass through. Therefore, the channel 1123-1 is called a limiting channel, which can limit the radial sway of the second connecting rod 1112, making the axial movement of the second connecting rod 1112 more stable, and thus the transmission more stable, which can effectively improve the stability of the valve clamping device 100 during use.

[0236] Furthermore, a limiting groove 1124-1 can be provided on the inner wall of the distal end of the support member 112. When the distal end of the second connecting rod 1112 moves to the distal end of the support member 112, it can be accommodated in the limiting groove 1124-1. Specifically, when the valve clamping device 100 is in the closed state, that is, when the clamping member 121 is clamped on the main body 110, the distal end of the second connecting rod 1112 is accommodated in the limiting groove 1124-1. The limiting groove 1124-1 can limit the radial sway of the second connecting rod 1112, which can further improve the stability of the valve clamping device 100 in the closed state and improve the edge-to-edge repair effect.

[0237] In some embodiments of this application, the main body 110 of the valve clamping device 100 further includes a connecting structure 116 for docking with the delivery system 200. The distal end of the catheter of the delivery system 200 and the proximal end of the main body 110 of the valve clamping device 100 are connected or disconnected via a clutch mechanism. This clutch mechanism has a clutch device located at the distal end of the catheter and a connecting structure 116 located at the proximal end of the main body 110 of the valve clamping device 100. These two parts cooperate with each other and are connected or disconnected under the action of a proximal operating handle of the delivery system 200. The connecting structure 116 can be understood as the proximal portion of the main body 110 of the valve clamping device 100 in the clutch mechanism. The above embodiments of this application do not limit the specific clutch mechanism.

[0238] However, in some embodiments, after the implanted device (such as the valve clamping device in the above embodiments) is delivered to the affected area and implanted, it is of great significance to find a way to more easily and quickly disconnect the implanted device from the catheter in order to reduce the difficulty of operation for the operator.

[0239] In view of this, the present application provides a clutch device for connecting the valve clamping device to the distal end of the catheter during the delivery of the valve clamping device, and for quickly detaching the valve clamping device after implantation. The device is simple to operate and can be used in complex surgical environments, reducing harm or discomfort to the patient.

[0240] Please refer to Figure 51 and Figure 52 This is a three-dimensional structural schematic diagram of a clutch device provided in an embodiment of this application, wherein... Figure 51 This is a schematic diagram of the clutch mechanism in its natural state. Figure 52 This is a schematic diagram of the clutch device under external force. The clutch device 215 is disposed at the distal end of the implanted catheter 213 and is used to connect or disconnect the valve clamping device. The clutch device 215 includes at least two clamping members 2150, each clamping member 2150 including an elastic part 2151 and a clamping part 2152. The elastic part 2151 is connected between the distal end of the implanted catheter 213 and the clamping part 2152, such that the clamping member 2150 opens relative to the central axis of the clutch device 215 (shown by the dotted line in the figure) in its natural state (i.e., without external force). Grooves 52-1 are provided on both sides of the distal end of the clamping part 2152. Under external force, at least two clamping members 2150 clamp in parallel, and there is a gap G between the side edges of the clamping parts 2152 of adjacent clamping members 2150, and the grooves 52-1 of adjacent clamping members 2150 are joined to form an opening intersecting with the gap G.

[0241] Thus, during the delivery of the valve clipping device, its connecting structure is engaged by the grooved opening, locking the valve clipping device at the distal end of the clutch. When the external force is removed, the clamping element opens naturally. Because the opening is formed by the mating joint, it quickly releases the engagement of the connecting structure, allowing for rapid disengagement of the valve clipping device. This allows for rapid disengagement even in complex surgical environments, reducing harm or discomfort to the patient. The surgeon can also achieve a simple and quick operation by simply removing the component applying the external force, with less resistance to overcome, reducing the difficulty for the operator and improving surgical outcomes.

[0242] The aforementioned clamping element 2150 opens at an angle relative to the central axis (shown by the dotted line in the figure) in its natural state. This angle is, for example, an acute angle, ranging from 20° to 40° (including the boundary value). This configuration balances disengagement efficiency with minimizing the impact of the opened clamping element 2150 on the surrounding tissues at the implantation site.

[0243] Optionally, the opening of the groove 52-1 of the adjacent clamping member 2150 is perpendicular to the gap G between the side edge of the clamping portion 2152 of the adjacent clamping member 2150. In this way, when the clamping members are clamped in parallel, they can provide a more stable connection for the valve clamping device, and during disengagement, they are subject to less resistance or interference, and can achieve release more quickly.

[0244] In some embodiments of this application, the clamping member 2150 may further include a mating member 2153, which is disposed at the connection between the elastic part 2151 and the clamping part 2152 and extends into the internal space of the clutch device 215; the mating member 2153 has a through hole 53-1, and when the through holes 53-1 of the mating members 2153 of at least two clamping members 2150 are abutted together, the at least two clamping members 2150 are parallel to each other. When no external force is applied, the clamping members 2150 are open relative to the central axis (shown by the dotted line in the figure). When the valve clamping device 100 is delivered, the distal end 2141 of the delivery rod 214 passes through the implantation catheter 213 and further passes through the through hole 53-1 of the mating member 2153, so that the different clamping members 2150 are clamped together (e.g., Figure 52 (As shown). After the valve clamping device 100 is implanted, the operator can control the delivery rod 214 to be pulled out from the occlusive member 2153, and the occlusive member 2150 opens without external force, releasing the connecting structure 116 of the valve clamping device. The occlusive member 2153 is located at the connection between the elastic part 2151 and the occlusive part 2152, which makes it easier for the delivery rod 214 to pass through the through hole 53-1.

[0245] In other embodiments, the mating members may not be provided, and the external force may be provided by the sleeve. When the valve clamping device 100 is delivered, the sleeve may be fitted onto at least two clamping members 2150, so that at least two clamping members 2150 are parallel and clamped together. After the valve clamping device 100 is implanted, the operator can control the sleeve to be withdrawn from the implantation catheter 213, and the at least two clamping members 2150 will open, thereby realizing the detachment of the valve clamping device.

[0246] Furthermore, please refer to the references. Figure 53 This is a side view of a clutch device provided in an embodiment of this application. The engaging member 2153 includes a connecting portion 53-2 and an engaging portion 53-3, with a through hole 53-1 penetrating the engaging portion 53-3. The engaging portions 53-3 of the engaging members 2153 of different engaging members 2150 have a positional difference of at least a first thickness on their respective engaging members 2150. Thus, when at least two engaging members 2150 are engaged in parallel, the engaging portions 53-3 can engage together, thereby aligning the through hole 53-1. This first thickness is the thickness of the engaging portion 53-3. In one implementation, the above positional difference can be achieved by designing different lengths for the connecting portions 53-2 of different engaging members 2153; in another implementation, the above positional difference can be achieved by varying the position of the connecting portions of different engaging members on their respective engaging members.

[0247] In the embodiments shown above, after the delivery rod 214 is removed from the mating member 2153, the shape of the opening changes simultaneously when the clamping member 2150 is opened, becoming a groove independent of the different clamping members, and quickly releasing the connection structure of the valve clamping device.

[0248] In some embodiments of this application, the clamping portion 2152 has a hollow structure 52-2, which is disposed between a first position and a second position. The first position is where the groove 52-1 is located on the clamping portion 2152, and the second position is where the connection between the elastic portion 2151 and the clamping portion 2152 is located on the clamping portion 2152. This allows for material reduction in the clamping portion 2152, resulting in greater toughness and lower stiffness during the opening and closing movements of the valve clamping device during connection and disconnection.

[0249] The figure shows two clamping members 2150 as an example, and the clamping members 2150 are arranged opposite to each other; in other embodiments, more clamping members 2150 may be included, which are symmetrically distributed on the periphery of the catheter 213 or symmetrically arranged with respect to the central axis.

[0250] In some embodiments of this application, please refer to [the relevant documentation]. Figure 53The engaging portion 2152 has a flat section 52-3, which extends from the hollow structure 52-2 to the distal edge of the engaging portion 2152. The flat section 52-3 has arc-shaped sections 52-4 on both sides, and the groove 52-1 is disposed within the arc-shaped sections 52-4. This structural design of the flat section allows for better engagement with the connecting part of the valve clamping device when the clutch device is connected. This not only maintains a stable connection of the valve clamping device in the connected state but also reduces resistance during disengagement, enabling rapid disengagement.

[0251] Accordingly, please refer to Figure 54 and Figure 55 This is a schematic diagram of the connection structure of two valve clamping devices provided in the embodiments of this application. Figure 54 and Figure 55 As shown, the valve clamping device 100 includes a main body 110, and a connecting structure 116 is provided at the proximal end of the main body 110, and the connecting structure 116 has a protruding portion 1161. As shown, when the valve clamping device 100 is delivered, at least two clamping members 2150 of the clutch device 215 clamp in parallel, and the protruding portion 1161 of the connecting structure 116 is accommodated in the opening, and the valve clamping device 100 is connected to the clutch device 215. When the valve clamping device 100 is implanted, at least two clamping members 2150 of the clutch device 215 open in the natural state, the protruding portion 1161 of the connecting structure 116 disengages from the opening, and the valve clamping device 100 is detached from the clutch device 215.

[0252] like Figure 54 As shown, in some embodiments of this application, the connecting structure 116 has a flat portion 1162 to match the flat section 52-3 of the clamping portion 2152 in the above embodiments, so that the connecting structure 116 of the clutch device 215 and the valve clamping device 100 fits better. In this way, not only can the valve clamping device be kept stably connected in the connected state, but also the resistance force can be reduced and the disassembly can be completed quickly during disassembly.

[0253] like Figure 55 As shown, in some embodiments of this application, the two sides of the protruding portion 1161 and the intersecting surface 1162' form a groove 1163, and the depth of the groove 1163 matches the thickness of the engaging portion 2152 of the engaging member 2150 of the clutch device 215. Further reference... Figure 37 When the clutch device 2155's clamping parts 2150 are parallel and clamped, the edge of the groove 52-1 engages with the slot 1163. At this time, the engagement of the slot 1163 of the connecting structure 116 with the edge of the groove 52-1 further improves the connection stability between the clutch device and the valve clamping device.

[0254] In the above embodiments, the grooves 52-1 of the different engaging members 2150 are symmetrically arranged. In other embodiments, the grooves 52-1 of the different engaging members 2150 can be asymmetrically arranged, that is, the size of the grooves 52-1 (e.g., Figure 53 As shown, the lateral depth (H) of the grooves on the clamping portion 2152 is different. Thus, the connecting structure of the valve clamping device accommodated in the opening has the same or different proportions in the portions of the different grooves. For example, in two adjacent clamping members, the size of the groove on one clamping member (referred to as the first clamping member for distinction) is larger than the size of the groove on the other clamping member (referred to as the second clamping member for distinction). Thus, when the two clamping members clamp together, the proportion of the connecting structure accommodating the opening in the first clamping member is greater than the proportion in the second clamping member. This application does not limit this proportion.

[0255] Please refer to Figure 56 and Figure 57 These are, respectively, a three-dimensional structural schematic diagram and a side view of a clutch device connected with a valve clamping device provided in the embodiments of this application. Figure 56 and Figure 57 As shown, the clutch device 215 includes at least two clamping members 2150, each clamping member 2150 comprising an elastic portion 2151 and a clamping portion 2152. The elastic portion 2151 is connected between the distal end of the implanted catheter 213 and the clamping portion 2152, such that the clamping member 2150 opens relative to the central axis in its natural state (i.e., without external force). The distal end of the clamping portion 2152 is provided with an opening O. This opening O matches the connecting structure 116 of the valve clamping device. When the clamping member 2150 clamps against the proximal end of the valve clamping device under external force, the different clamping members 2150 clamp in parallel, and there is a gap G between the edges of the clamping portions 2152 of adjacent clamping members 2150. The protruding portion 1161 of the connecting structure 116 of the valve clamping device extends into the opening O, locking the valve clamping device at the distal end of the clutch device 215.

[0256] Compared to existing clutches, the clutch device 215 uses an enveloping method to connect the valve clamping device, making it easier for the valve clamping device to be removed after implantation.

[0257] The opening O can be formed by providing a groove 52-1 at the distal end of the clamping member 2150 in the above embodiments, so that the clamping members 2150 are aligned when they are parallel. In other embodiments, the opening O can also be formed entirely at the non-edge position of the clamping portion 2152.

[0258] For example, please refer to Figure 58 This is a three-dimensional structural diagram of another clutch device connected to a valve clamping device provided in an embodiment of this application. The clutch device differs from the previous embodiment in that the opening O is fully disposed at the distal end of the clamping portion 2152. For example... Figure 58 As shown, the clutch device 215 includes an elastic part 2151 and a clamping part 2152. The elastic part 2151 is connected between the distal end of the conduit 213 and the clamping part 2152, so that the clamping member 2150 is open relative to the central axis of the clutch device in its natural state, and at least two clamping members 2150 are clamped in parallel under the action of external force. The engaging portion 2152 includes a first segment 52-P1 and a second segment 52-P2. The proximal end of the first segment 52-P1 is connected to the elastic portion 2151, and the distal end of the first segment 52-P1 is connected to the second segment 52-P2. The width of the second segment 52-P2 is greater than the width of the first segment 52-P1, such that when at least two engaging members 2150 engage in parallel, the width of the first gap G1 formed between the side edges of the first segment 52-P1 of the engaging portion 2152 of adjacent engaging members 2150 is greater than the width of the second gap G2 formed between the side edges of the second segment 52-P2. The proportion of the second segment 52-P2 in the engaging portion 2152 in a first direction is less than or equal to 1 / 3, for example, 10%-30% (including boundary values). The first direction is the direction in which the engaging portion 2152 extends from the proximal end connected to the elastic portion 2151 to the distal end of the engaging portion 2152.

[0259] When connecting the valve clamping device, the above-mentioned clutch mechanism uses a larger contact area in the second segment 52-P2 to improve the connection stability of the valve clamping device. Furthermore, it creates a larger gap G1 between the first segments 52-P1, reducing interference during disengagement and allowing for faster disengagement of the valve clamping device. This balances stability with ease of disengagement.

[0260] Furthermore, the width of the second segment 52-P2 is 110%-150% (including boundary values) of the width of the first segment 52-P1, meaning the width of the second segment is 10%-50% greater than the width of the first segment. This further improves the connection stability of the valve clamping device during delivery. The width of the second gap G2 can be zero, meaning that when adjacent clamping members 2150 are parallel and clamped, the side edges of the second segment 52-P2 contact each other, increasing the clamping contact area and further improving stability. Alternatively, as... Figure 58 The width of the second slit G2 can be greater than zero, which allows for faster disassembly of the valve clamping device.

[0261] The location of the opening O can be implemented in several ways: In one implementation, the opening O is located at the junction of the first segment 52-P1 and the second segment 52-P2, and the proximal edge of the opening O is located at the first segment 52-P1, and the distal edge is located at the second segment 52-P2; In another implementation, the opening O is located at the first segment 52-P1, and the distal edge of the opening O is located at or near the junction of the first segment 52-P1 and the second segment 52-P2; In yet another implementation, the opening O is located at the second segment 52-P2, and the proximal edge of the opening O is located at or near the junction of the first segment 52-P1 and the second segment 52-P2.

[0262] In other embodiments, the first gap can also be used to engage the connecting structure of the valve clamping device, thus eliminating the need for an opening. For example, the width of the first gap G1 matches the protrusion 1161 of the connecting structure 116 of the valve clamping device. When the clutch device 215 engages the valve clamping device 100, the protrusion 1161 is accommodated in the first gap G1 and abuts against the second segment 52-P2. Thus, similar to the above... Figure 56 and Figure 57 In the illustrated embodiment, the first slit G1 is joined together. After the external force is removed, the first slit G1 and the second segment 52-P2 quickly disengage from the connecting structure 116, allowing the valve clamping device 100 to be quickly disassembled. This rapid disassembly can be achieved even in complex surgical environments, reducing harm or discomfort to the patient. The surgeon can also perform a simple and quick operation by simply removing the component that applies the external force, and the resistance to overcome when removing the component is smaller, reducing the difficulty for the operator and improving the surgical outcome.

[0263] Furthermore, the clutch device 215 may also have a structure similar to the clutch device in the above embodiments, such as the engaging member 2153 and the hollow structure 52-2. The difference is that the hollow structure 52-2 is located in the first segment 52-P1. In one implementation, the width of the hollow structure 52-2 accounts for 40%-90% (including boundary values) of the width of the first segment 52-P1. In this way, the connection stability of the engaging part 2152 to the valve clamping device can be satisfied, and the width of the first gap G1 can be maximized, thereby improving the ease of disassembly.

[0264] Accordingly, such as Figure 2As shown, this application embodiment also provides a delivery system 200 and a valve repair system including the delivery system. The delivery system 200 includes an implantation catheter 213 and any of the above-mentioned clutch devices 215 disposed at the distal end of the implantation catheter for connecting or disconnecting the valve clamping device 100. Further, the delivery system 200 also includes a delivery rod 214, which passes through the implantation catheter 213 and is used to provide the external force acting on the clutch device 215; when delivering the valve clamping device 100, the distal end of the delivery rod 214 applies the external force to the clamping member 2150 of the clutch device 215, so that at least two clamping members 2150 clamp in parallel; when disconnecting the valve clamping device 100, the delivery rod 214 removes the external force from the clamping member 2150 of the clutch device 215. For example, when the delivery rod 214 passes through the through hole 53-1 of the mating member 2153 of at least two clamping members 2150, the through holes 53-1 of the mating members 2153 are joined together, and the at least two clamping members 2150 are parallel to each other.

[0265] In the above embodiments, the descriptions of each embodiment have different focuses. For parts that are not described in detail or recorded in a certain embodiment, please refer to the relevant descriptions of other embodiments.

[0266] It should be noted that the above embodiments can be freely combined as needed. The above are only some embodiments of this application. For those skilled in the art, several improvements and modifications can be made without departing from the principles of this application, and these improvements and modifications should also be considered within the protection scope of this application.

Claims

1. A valve-clamping device, characterized by include: main body; A clamping body is installed on the main body; The main body includes a transmission assembly and an attachment. The transmission assembly includes a first connecting rod and a second connecting rod. The distal end of the first connecting rod and the proximal end of the second connecting rod are provided with a transmission structure. The first connecting rod and the transmission structure are disposed within the attachment. The inner sidewall of the attachment is provided with an internal thread, and the outer sidewall of the first connecting rod is provided with an external thread. The internal thread and the external thread are helically matched. The transmission structure transmits axial movement between the first connecting rod and the second connecting rod, while preventing the transmission of radial movement tendencies to the second connecting rod. The clamping body includes a clamping member, which is hinged to the distal end of the second connecting rod. The axial movement of the second connecting rod drives the opening and closing movement of the clamping member, changing the angle between the clamping member and the main body.

2. The valve clamping device according to claim 1, characterized in that, The transmission structure includes a first limiting structure and a second limiting structure; The first limiting structure is disposed at the far end of the first connecting rod, and the second limiting structure is disposed at the near end of the second connecting rod. When the first connecting rod or the second connecting rod moves axially, the first limiting structure and the second limiting structure abut against each other axially.

3. The valve clamping device according to claim 2, characterized in that, The axial contact between the first limiting structure and the second limiting structure restricts the relative movement of the first link and the second link in one axial direction, or the axial contact between the first limiting structure and the second limiting structure restricts the relative movement of the first link and the second link in two axial directions.

4. The valve clamping device according to claim 3, characterized in that, The second limiting structure has a concave side surface, and the first limiting structure has an extension extending into the inside of the first connecting rod, the extension being located within the groove of the concave side surface.

5. The valve clamping device according to claim 3, characterized in that, The first limiting structure includes a limiting member disposed at the distal end of the first connecting rod, the limiting member having a chamber with a distal opening, the proximal end of the second connecting rod passing through the distal opening, the second limiting structure at the proximal end of the second connecting rod being accommodated in the chamber, and the maximum dimension of the second limiting structure being larger than the dimension of the distal opening; or, The second limiting structure includes a limiting member disposed at the proximal end of the second link, the limiting member having a chamber having an opening toward the proximal end, the distal end of the first link passing through the opening toward the proximal end, the first limiting structure at the distal end of the first link being accommodated in the chamber, and the maximum size of the first limiting structure being greater than the size of the opening toward the proximal end.

6. The valve clamping device according to claim 5, characterized in that, The second limiting structure located in the cavity of the limiting member is spherical or ellipsoidal; or, The first limiting structure located in the cavity of the limiting member is spherical or ellipsoidal.

7. The valve clamping device according to claim 5, characterized in that, The first limiting structure includes a limiting member disposed at the distal end of the first connecting rod, the chamber of the limiting member further having a proximal opening, the distal end of the first connecting rod passing through the proximal opening and abutting against the second limiting structure at the proximal end of the second connecting rod during axial movement towards the distal end; or, The second limiting structure includes a limiting member disposed at the proximal end of the second link, the chamber of the limiting member further having a distal opening, the proximal end of the second link passing through the distal opening and abutting against the first limiting structure at the proximal end of the first link during distal axial movement within the chamber.

8. The valve-clamping device defined in claim 2, wherein The first limiting structure is integrally formed with the first connecting rod, and the second limiting structure is integrally formed with the second connecting rod; or... The first limiting structure is integrally formed with the first connecting rod, and the second limiting structure is fixedly connected to the second connecting rod; or... The first limiting structure is fixedly connected to the first connecting rod, and the second limiting structure is integrally formed with the second connecting rod; or... The first limiting structure is fixedly connected to the first connecting rod, and the second limiting structure is fixedly connected to the second connecting rod.

9. The valve clamping device according to claim 1, characterized in that, At least one of the abutting surfaces in the transmission assembly has a raised structure.

10. The valve clamping device according to claim 1, characterized in that, The first link has an internal space, the cross-section of which is non-circular.

11. The valve clamping device according to claim 10, characterized in that, The cross-section of the internal space is elliptical, rectangular, triangular, or racetrack-shaped.

12. The valve-clamping device defined in claim 1, wherein The clamp also includes: The grabbing element is disposed between the main body and the clamping element.

13. A valve repair system, characterized in that, include: The valve clamping device as described in any one of claims 1-12; A delivery system for delivering and controlling the valve clamping device.

14. The valve repair system of Ciaim 13, wherein, The delivery system includes a catheter and a delivery device. The delivery device includes a control mechanism and a delivery rod. The proximal end of the delivery rod is connected to the control mechanism. The distal end of the delivery rod passes through the catheter and acts radially on the transmission assembly of the valve clamping device. The distal end of the delivery rod has a non-circular cross-section.

15. The valve repair system of claim 14, wherein, The contact surface between the delivery rod and the second link of the transmission assembly of the valve clamping device has a raised structure.

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