A high-performance medical pure titanium anastomotic suture and its preparation method

Abstract

This invention discloses a high-performance medical pure titanium anastomotic suture and its preparation method. The preparation method includes the following steps: after pretreatment of sponge titanium, titanium ingots are produced by a triple melting method using an electron beam cold hearth furnace (EB), a water-cooled copper crucible vacuum levitation induction furnace (ISM), and a vacuum consumable arc furnace (VAR). The titanium ingots are then subjected to testing and analysis, hot working, fine cold drawing, and surface treatment to obtain pure titanium anastomotic sutures. The medical pure titanium anastomotic sutures prepared by this invention exhibit high elemental uniformity, ultrafine grain structure, and good stability and consistency.

Description

Technical Field

[0001] This invention relates to a high-performance medical pure titanium anastomotic suture and its preparation method, belonging to the field of biomedical materials manufacturing. Background Technology

[0002] Anastomosis is one of the most commonly used methods in surgical clinical practice. It is crucial for both suturing the inner and outer layers of skin and for anastomosing internal tissues and organs after surgery. With the development of medical technology, anastomosis techniques are constantly evolving. Anastomotic sutures are the primary medical materials used for anastomosing human tissues. From the original ordinary polymer sutures to the more recent biodegradable and absorbable biomaterial sutures, research and development have been ongoing both domestically and internationally. Although various polymer sutures are widely used in anastomosing human tissues, their inherent foreign body nature makes them highly susceptible to infection after surgery, requiring a period of anti-infection treatment, resulting in long treatment courses and significant side effects for patients. In recent years, research has begun abroad on using pure titanium ultrafine sutures as anastomotic sutures in anastomotic devices, achieving very good results. This is because titanium and titanium alloys have good biocompatibility with human tissues and certain antibacterial properties, allowing them to remain in human tissues long-term without allergic reactions, which is highly beneficial for patient treatment and recovery.

[0003] In clinical use, pure titanium anastomotic sutures, being made of ultra-fine titanium wire, require not only high tensile strength but also excellent bending and winding properties during anastomosis. Therefore, pure titanium anastomotic sutures need to possess both good strength and excellent ductility. Furthermore, they must exhibit consistency and stability in their tissue and mechanical properties. Summary of the Invention

[0004] In view of this, the present invention provides a high-performance medical pure titanium anastomotic suture and its preparation method. Compared with pure titanium wire, the medical pure titanium anastomotic suture prepared by the present invention has high elemental uniformity, ultrafine grain structure, and good stability and consistency.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A method for preparing high-performance medical pure titanium anastomotic sutures is characterized in that sponge titanium is pretreated and then smelted into titanium ingots using a triple melting method of electron beam cold hearth furnace (EB), water-cooled copper crucible vacuum levitation induction furnace (ISM), and vacuum consumable arc furnace (VAR). The titanium ingots are then subjected to testing and analysis, hot working, fine cold drawing, and pure titanium anastomotic suture surface treatment to obtain pure titanium anastomotic sutures.

[0007] The beneficial effects of adopting the above technical solution are as follows: Titanium ingots are the foundation for the production of any processed material, and the quality of the ingots has a decisive impact on the quality of the finished product. Generally, both domestically and internationally, the method of melting titanium ingots twice or more using a vacuum arc remelting furnace (VAR) or a vacuum electron beam furnace is commonly used. To ensure the quality of the titanium ingots, this invention is the first in China to adopt the EB+ISM+VAR melting method for producing titanium ingots. Specifically: the first melting is performed in an electron beam cold hearth furnace (EB), utilizing the high vacuum and high temperature during the melting process to remove low-melting-point impurities and bulk impurities from the sponge titanium, achieving a purification effect; the second melting is performed in a water-cooled copper crucible vacuum levitation induction furnace (ISM), ensuring uniform composition and preventing crucible material contamination; and the third melting is performed using a vacuum arc remelting furnace (VAR), adjusting the ingot microstructure, changing the distribution of impurity elements, and improving the consistency of the titanium ingot.

[0008] Preferably, the pretreatment specifically involves: selecting sponge titanium of grade 0 or above according to national standards, mixing the sponge titanium from each batch, and loading it into a vacuum degassing furnace for vacuum degassing at a temperature of 120-150℃ and a vacuum degree of 1×10⁻⁶. -2 mmHg, time > 12 hours.

[0009] The beneficial effects of adopting the above technical solution are as follows: The raw material used for pure titanium ingots is sponge titanium. According to the actual situation of domestic sponge titanium products, sponge titanium is produced by magnesium reduction of titanium tetrachloride. Sponge titanium contains more than 10 kinds of gaseous impurities and other elements. The distribution and consistency of these impurities seriously affect the quality of titanium ingots. Therefore, this invention first pre-treats the sponge titanium to remove gaseous impurities and other elements.

[0010] Preferably, the electron beam cold hearth furnace (EB) melting conditions are: melting vacuum degree ≥ 1.0 × 10⁻⁶. -3 The melting temperature is >2100℃, the molten pool temperature is >1800℃, and after melting, the furnace is cooled under vacuum to <100℃ before being removed from the furnace.

[0011] Preferably, the melting conditions in the water-cooled copper crucible vacuum levitation induction furnace (ISM) are: melting vacuum degree ≥ 2.0 × 10⁻⁶. -3 Millimeters of mercury, melting temperature >1950℃, molten pool temperature >1800℃, casting ingot temperature >1700℃, ingot cooled to <80℃ under vacuum, and then removed from the furnace after vacuum is broken.

[0012] Preferably, the VAR melting conditions in the vacuum self-consuming electric arc furnace are: melting vacuum degree ≥ 1.3 × 10⁻⁶. -3 Millimeters of mercury, melting temperature >1800℃, molten pool temperature: 1750℃, after melting, the ingot is cooled to room temperature under vacuum in the furnace, the vacuum is broken, and it is taken out of the furnace.

[0013] Preferably, the detection and analysis specifically involves: the titanium ingot undergoing flaw detection to remove risers and shrinkage cavities; the surface of the titanium ingot undergoing cold working and peeling treatment; then, samples are taken from the upper, middle, and lower sides of the titanium ingot's side surface, as well as from the center of the titanium ingot's end face, to analyze the gas and impurity composition; the titanium ingot composition is controlled within the following range by mass percentage: O < 0.09%, N < 0.010%, H < 0.008%, C < 0.015%, Fe < 0.060%, with Ti as the balance.

[0014] Preferably, the hot working includes forging, hot rolling, homogenization heat treatment, and grain refinement drawing;

[0015] The forging blank is heated in an electric resistance furnace. The free forging blank of more than 2 tons breaks the casting structure. After one forging, it is sawn and cut into blanks according to technical requirements. It is then heated and upsetting forged a second time. The upsetting and upsetting forging is carried out more than 3 times in each direction to form a hot-rolled blank of Φ120-130mm. The surface oxide scale is removed by cold working. The blank heating temperature is 890-950℃, the forging temperature is 800-900℃, and the upsetting and upsetting forging temperature is 700-800℃.

[0016] The hot rolling process involves processing with an ultra-high deformation rate above the recrystallization temperature. It employs a single heating and multi-pass rolling process with air cooling. Heating is carried out in an electric resistance furnace, and hot rolling is performed using a high-speed, high-precision hot rolling mill. Heating temperature: 700-850℃, rolling temperature: 650-800℃, deformation size: Φ120→Φ6.0mm.

[0017] The homogenization heat treatment utilizes a pit-type annealing furnace for stress-relief homogenization annealing; heat treatment temperature: 500-560℃, holding time: >0.5H;

[0018] The grain refinement drawing process involves high deformation rate drawing and rapid cooling at the recrystallization temperature, performed on an argon-blown rapid cooling continuous wire drawing machine; the processing size range is Φ6.0→Φ0.8mm, the processing temperature is 480-580℃, and the cooling intensity is >200℃ / S.

[0019] Preferably, the fine cold-drawn wire deformation size range is: Φ0.8-1.0mm (inlet wire diameter) → Φ0.20-0.30mm (outlet wire diameter), and the linear speed is: 1000-3000mm / minute.

[0020] Preferably, the surface treatment of the pure titanium anastomotic suture involves ultrasonic cleaning of the suture surface with alcohol. The suture is fed by a suture feeding device and passes through an ultrasonic device filled with alcohol liquid. Under the action of ultrasonic waves, the liquid repeatedly cleans the surface of the suture. The suture is then continuously sent out from the outlet, quickly dried by hot air, and wound into the finished spool by a suture winding mechanism.

[0021] The beneficial effects of this invention are as follows:

[0022] Pure titanium is the most widely used product. Medical anastomotic sutures use pure titanium cores, defined by national standards, with oxygen and iron as alloying reinforcing elements. Therefore, controlling the composition range is extremely difficult. The specific function of the triple melting method in this invention is:

[0023] ①EB furnace melting: The high temperature generated by the electron beam and the high vacuum during the furnace melting process are used to remove low-melting-point magnesium, chlorine, carbon and silicon elements from sponge titanium, thereby achieving a purification effect.

[0024] ② Suspension induction furnace melting: Melting is carried out without crucible contamination. The molten pool consists entirely of molten metal. Under electromagnetic stirring, elements that are very prone to segregation, such as iron, boron, and oxygen, are thoroughly and evenly mixed. In addition, the ingot is poured by tilting, resulting in a more consistent composition throughout the ingot. This achieves complete compositional homogenization.

[0025] ③ Consumable metallurgy is a common method for melting pure titanium ingots. By controlling the melting rate and cooling intensity during the melting process, the grain size and solidification rate of the ingot can be controlled, ensuring the consistency of the microstructure. This plays a role in controlling the microstructure of the ingot.

[0026] ④ Adding boron (B) during compositional changes is a method that has been used to refine the grains. However, it has not been able to solve the problem of B inclusions. Triple melting can solve this problem very well.

[0027] ⑤ The change of oxygen and iron to ranges in the composition control further clarifies that they are used as alloying elements rather than as impurities, which is different from existing technologies.

[0028] Existing pure titanium has high strength but low plasticity, while this invention, through long-term exploration, can achieve both high strength and high plasticity. Detailed Implementation

[0029] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0030] Example 1

[0031] 1. Production process of pure titanium ingots

[0032] ① Raw material selection and pretreatment

[0033] The raw material used for pure titanium ingots is sponge titanium. According to the actual situation of domestic sponge titanium products, sponge titanium is produced by magnesium reduction of titanium tetrachloride. Sponge titanium contains more than 10 kinds of gaseous impurities and other elements. The distribution and consistency of these impurities seriously affect the quality of titanium ingots. Therefore, sponge titanium must be pretreated.

[0034] Select sponge titanium of grade 0 or above according to national standards, and use a mixer to perform large-scale mixing of sponge titanium in each batch.

[0035] The titanium sponge is placed in a vacuum degassing furnace for degassing at a temperature of 120-150℃. The vacuum level is 1×10⁻⁶. -2 mmHg, time: >12 hours.

[0036] ②EB furnace smelting

[0037] The pretreated sponge titanium is added to the hopper of the EB furnace (produced by TÜV Rheinland, model E2000), and a vacuum is drawn. After reaching the ultimate vacuum, melting begins. After melting, the furnace is cooled under vacuum to <100°C, and then the furnace is removed from the vacuum.

[0038] Melting vacuum degree: ≥1.0×10 -3 mmHg;

[0039] Melting temperature: >2100℃;

[0040] Molten pool temperature: >1800℃.

[0041] ③ISM Smelting

[0042] The sponge titanium smelted in the EB furnace was added to the ISM melting furnace (imported suspension furnace from the Institute of Metal Research, Chinese Academy of Sciences, model G-100), with a melting vacuum degree ≥2.0×10⁻⁶. -3 Millimeters of mercury, melting temperature >1950℃, molten pool temperature >1800℃, casting ingot temperature >1700℃, ingot cooled to <80℃ under vacuum, and then removed from the furnace after vacuum is broken.

[0043] ④VAR smelting

[0044] The titanium ingots produced by ISM melting are processed and welded into consumable electrodes, which are then placed on the electrode rods of a vacuum consumable arc furnace. The furnace door is closed and a vacuum is drawn. Once the ultimate vacuum level is reached, the consumable electrode melting begins. The melting current and the cooling water temperature of the water-cooled copper crucible are adjusted to control the cooling intensity, ensuring that the ingot's microstructure is essentially uniform throughout. After melting, the ingot is cooled to room temperature under vacuum in the furnace, the vacuum is broken, and the ingot is removed from the furnace.

[0045] Melting vacuum degree: ≥1.3×10 -3 mmHg;

[0046] Melting temperature: >1800℃;

[0047] Melt pool temperature: 1750℃.

[0048] ⑤ Titanium ingot processing

[0049] After VAR melting, the finished ingots undergo flaw detection to remove risers and shrinkage cavities, cold working to remove the outer skin, sampling from the top, middle, and bottom of the ingot surface, and sampling from the center of the ingot end face to analyze the gas and impurity composition.

[0050] Titanium ingot composition control range (mass percentage)

[0051] O 0.07-0.12%

[0052] N < 0.010%;

[0053] H < 0.008%;

[0054] C < 0.015%;

[0055] Fe 0.06-0.15%

[0056] B < 0.003%

[0057] Ti balance.

[0058] 2. Hot working process

[0059] ①Ingot forging and billet preparation

[0060] Pure titanium ingots are heated in an electric resistance furnace, and free forging of more than 2 tons is used to break down the casting structure. After one forging, the ingots are sawn and cut according to technical requirements. They are then heated and forged a second time, and forged in all directions more than 3 times to form hot-rolled billets of Φ120-130mm. The surface oxide scale is then removed by cold working.

[0061] Billet heating temperature: 890-950℃;

[0062] Forging temperature: 800-900℃;

[0063] Forging temperature: 700-800℃.

[0064] ② Hot rolling

[0065] Hot rolling is the most crucial control step in ensuring the performance of pure titanium mating wire. Processing with an ultra-high deformation rate above the recrystallization temperature is necessary to guarantee the refinement of the grain structure. Heating is carried out in an electric resistance furnace using a high-speed, high-precision hot rolling mill (RZ380 hot rolling mill).

[0066] Heating temperature: 700-850℃;

[0067] Rolling temperature: 650-800℃;

[0068] Deformation dimensions: Φ120→Φ6.0mm (single heating, multi-pass rolling, air cooling).

[0069] ③ Homogenization heat treatment

[0070] Hot-rolled finished Φ6.0mm wire rods require homogenization heat treatment to ensure consistent overall performance. Stress-relieving and homogenization annealing is performed using a pit-type annealing furnace.

[0071] Heat treatment temperature: 500-560℃;

[0072] Insulation time: >0.5H.

[0073] ④ Grain refinement during pulling

[0074] To ensure ultra-fine grain structure, this invention differs from traditional pure titanium wire processing methods by involving high deformation rate drawing and rapid cooling around the recrystallization temperature. The process is carried out on an argon-blown rapid-cooling continuous wire drawing machine.

[0075] Processing size range: Φ6.0→Φ0.8mm;

[0076] Processing temperature: 480-580℃;

[0077] Cooling intensity: >200℃ / S.

[0078] 3. Fine cold drawing

[0079] With a fixed chemical composition, the cold deformation rate of pure titanium mating wire determines the mechanical properties and surface quality of the finished product. Precision drawing is performed on a box-type wire drawing machine. Multiple drawing dies, made of tungsten-nickel hard alloy, are arranged inside the machine. The drawing speed is computer-controlled and adjustable. A self-developed phosphate emulsifier is used as the lubricant. The processing principle is as follows: pure titanium wire spools with a diameter of approximately Φ0.8mm are fed into the sealed wire drawing machine by a wire feeding mechanism. After continuous deformation processing by multiple dies arranged inside the machine, the mating wire is delivered from the exit port, and the spool mechanism automatically rewinds it into a Φ0.25mm diameter wire spool.

[0080] Wire drawing deformation size range: Φ0.8-1.0mm (inlet wire diameter) → Φ0.20-0.30mm (outlet wire diameter is adjustable according to mold size);

[0081] Linear speed: 1000-3000 mm / min.

[0082] 4. Surface treatment of pure titanium anastomotic sutures

[0083] As a material for human implantation, the surface of the anastomotic suture must be smooth, clean, and free of lubricants. This invention uses an alcohol-based ultrasonic cleaner to clean the surface of the anastomotic suture. The principle is as follows: the suture is fed by a suture feeding device, and then passes through an ultrasonic device filled with an alcohol liquid. Under the action of ultrasonic waves, the liquid repeatedly cleans the surface of the suture, and the suture is continuously discharged from the outlet. It is then quickly dried by hot air and wound into a finished spool by a suture winding mechanism.

[0084] 5. Examples

[0085] The mechanical properties of pure titanium anastomotic sutures are closely related to their oxygen content and processing deformation techniques. In actual clinical use, the diameter and specifications of the sutures vary depending on the organ and tissue. The following are actual test data for finished pure titanium anastomotic sutures (mechanical property testing was performed according to national standard GB / T13810-2017).

[0086] ① Matching wire specification Φ0.20mm

[0087] 0.08%;

[0088] N < 0.010%;

[0089] H < 0.008%;

[0090] C < 0.015%;

[0091] Fe 0.10%;

[0092] B 0.002%;

[0093] Ti balance.

[0094] Main production process parameters:

[0095] Raw material selection and pretreatment: Temperature 120℃. Vacuum degree 1×10⁻⁶. -2 mmHg, time 14 hours;

[0096] EB furnace melting: vacuum degree 1.0×10 -3 mmHg; melting temperature 2150℃; molten pool temperature 1900℃;

[0097] ISM melting: vacuum degree 2.0×10 -3 mmHg, melting temperature 1980℃, molten pool temperature 1850℃, casting ingot temperature 1750℃;

[0098] VAR melting: melting vacuum degree 1.3×10 -3 mmHg; melting temperature 1900℃; molten pool temperature: 1750℃.

[0099] The billet heating temperature is 900°C.

[0100] Forging temperature: 895℃;

[0101] Forging temperature: 760℃.

[0102] Hot rolling heating temperature: 770℃;

[0103] Rolling temperature: 760℃;

[0104] Deformation dimension: Φ120→Φ6.0mm;

[0105] Heat treatment temperature: 580℃;

[0106] Insulation time: 0.6 hours.

[0107] Processing size range: Φ6.0→Φ0.8mm;

[0108] Processing temperature: 500℃;

[0109] Cooling intensity: 250℃ / S.

[0110] Linear velocity: 1000 mm / min.

[0111] performance:

[0112] Cold drawing pass deformation rate: 50%

[0113] Total deformation rate before finished product: 200%

[0114] Tensile strength σb 880MPa;

[0115] Elongation δ62%;

[0116] Mechanical property: Reduction of area Ψ80%.

[0117] ② Matching wire specification Φ0.22mm

[0118] O 0.09%;

[0119] N < 0.010%;

[0120] H < 0.008%;

[0121] C < 0.015%;

[0122] Fe 0.12%;

[0123] B 0.002%;

[0124] Ti balance.

[0125] Main production process parameters:

[0126] Raw material selection and pretreatment: Temperature 150℃. Vacuum degree 1×10⁻⁶. -2 mmHg, time 13 hours;

[0127] EB furnace melting: melting vacuum degree 1.0×10 -3 mmHg; melting temperature 2200℃; molten pool temperature 1850℃;

[0128] ISM melting: melting vacuum degree 2.0×10 -3 mmHg, melting temperature 1960℃, molten pool temperature 1850℃, casting ingot temperature 1780℃;

[0129] VAR melting: melting vacuum degree 1.3×10 -3 mmHg; melting temperature 1900℃; molten pool temperature: 1750℃.

[0130] Billet heating temperature: 890°C;

[0131] Forging temperature: 865℃;

[0132] Forging temperature: 740℃.

[0133] Hot rolling heating temperature: 850℃;

[0134] Rolling temperature: 690℃;

[0135] Deformation dimension: Φ120→Φ6.0mm;

[0136] Heat treatment temperature: 530℃;

[0137] Insulation time: 0.7 hours.

[0138] Processing size range: Φ6.0→Φ0.8mm;

[0139] Processing temperature: 560℃;

[0140] Cooling intensity: 21℃ / S.

[0141] Linear velocity: 3000 mm / min.

[0142] performance:

[0143] Deformation rate per pass: 55%

[0144] Total deformation rate before finished product: 220%

[0145] σb 900MPa;

[0146] δ64%;

[0147] Ψ82.

[0148] ③ Matching wire specification Φ0.25mm

[0149] 0.10%;

[0150] N < 0.010%;

[0151] H < 0.008%;

[0152] C < 0.015%;

[0153] Fe 0.14%;

[0154] B 0.002%;

[0155] Ti balance.

[0156] Main production process parameters:

[0157] Raw material selection and pretreatment: Temperature 130℃. Vacuum degree 1×10⁻⁶. -2 mmHg, time 12.5 hours;

[0158] EB furnace melting: melting vacuum degree 1.0×10 -3 mmHg; melting temperature 2180℃; molten pool temperature 1900℃;

[0159] ISM melting: melting vacuum degree 2.0×10 -3 mmHg, melting temperature 2050℃, molten pool temperature 1850℃, casting ingot temperature 1780℃;

[0160] VAR melting: melting vacuum degree 1.3×10 -3 mmHg; melting temperature 1850℃; molten pool temperature 1750℃.

[0161] Billet heating temperature: 920℃;

[0162] Forging temperature: 860℃;

[0163] Forging temperature: 750℃.

[0164] Hot rolling heating temperature: 740℃;

[0165] Rolling temperature: 720℃;

[0166] Deformation dimension: Φ120→Φ6.0mm;

[0167] Heat treatment temperature: 560℃;

[0168] Insulation time: 0.6 hours.

[0169] Processing size range: Φ6.0→Φ0.8mm;

[0170] Processing temperature: 50-70℃;

[0171] Cooling intensity: 230℃ / S.

[0172] Linear velocity: 2000 mm / min.

[0173] performance:

[0174] Deformation rate per pass: 59%

[0175] Total deformation rate before finished product: 240%

[0176] σb 950MPa;

[0177] δ65%;

[0178] Ψ83.

[0179] The various embodiments in this specification are described in a progressive manner, with each embodiment focusing on its differences from other embodiments. Similar or identical parts between embodiments can be referred to interchangeably. For the apparatus disclosed in the embodiments, since they correspond to the methods disclosed in the embodiments, the description is relatively simple; relevant parts can be referred to the method section.

[0180] The above description of the disclosed embodiments enables those skilled in the art to make or use the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A method for preparing a high-performance medical pure titanium anastomotic suture, characterized in that, After pretreatment, sponge titanium is used to produce titanium ingots by a triple melting method of electron beam cold hearth furnace (EB), water-cooled copper crucible vacuum levitation induction furnace (ISM), and vacuum consumable arc furnace (VAR). The titanium ingots are then tested and analyzed, hot-processed, finely cold-drawn, and surface-treated with pure titanium mating wires to obtain pure titanium mating wires. The hot working process includes forging, hot rolling, homogenization heat treatment, and grain refinement drawing. The forging blank is heated in an electric resistance furnace. The free forging blank of more than 2 tons breaks the casting structure. After one forging, it is sawn and cut into blanks according to technical requirements. It is then heated and upsetting forged a second time. The upsetting and upsetting forging is carried out more than 3 times in each direction to form a hot-rolled blank of Φ120-130mm. The surface oxide scale is removed by cold working. The blank heating temperature is 890-950℃, the forging temperature is 800-900℃, and the upsetting and upsetting forging temperature is 700-800℃. The hot rolling process involves processing with an ultra-high deformation rate above the recrystallization temperature. It employs a single heating and multi-pass rolling process with air cooling. Heating is carried out in an electric resistance furnace, and hot rolling is performed using a high-speed, high-precision hot rolling mill. Heating temperature: 700-850℃, rolling temperature: 650-800℃, deformation size: Φ120→Φ6.0mm. The homogenization heat treatment utilizes a pit-type annealing furnace for stress-relief homogenization annealing; heat treatment temperature: 500-560℃, holding time: >0.5H; The grain refinement drawing process involves high deformation rate drawing and rapid cooling at the recrystallization temperature, performed on an argon-blown rapid cooling continuous wire drawing machine; the processing size range is Φ6.0→Φ0.8mm, the processing temperature is 480-580℃, and the cooling intensity is >200℃ / S.

2. The method for preparing a high-performance medical pure titanium anastomotic suture according to claim 1, characterized in that, The pretreatment specifically involves selecting sponge titanium of grade 0 or higher according to national standards, mixing the sponge titanium from each batch, and loading it into a vacuum degassing furnace for vacuum degassing at a temperature of 120-150℃ and a vacuum degree of 1×10⁻⁶. -2 mmHg, time > 12 hours.

3. The method for preparing a high-performance medical pure titanium anastomotic suture according to claim 1, characterized in that, The electron beam cold hearth furnace EB melting conditions are: melting vacuum degree ≥ 1.0 × 10⁻⁶ -3 The melting temperature is >2100℃, the molten pool temperature is >1800℃, and after melting, the furnace is cooled under vacuum to <100℃ before being removed from the furnace.

4. The method for preparing a high-performance medical pure titanium anastomotic suture according to claim 1, characterized in that, The melting conditions in the water-cooled copper crucible vacuum levitation induction furnace (ISM) are: melting vacuum degree ≥ 2.0 × 10⁻⁶. -3 Millimeters of mercury, melting temperature >1950℃, molten pool temperature >1800℃, casting ingot temperature >1700℃, ingot cooled to <80℃ under vacuum, and then removed from the furnace after vacuum is broken.

5. The method for preparing a high-performance medical pure titanium anastomotic suture according to claim 1, characterized in that, The vacuum self-consuming electric arc furnace (VAR) melting conditions are: melting vacuum degree ≥ 1.3 × 10⁻⁶. -3 Millimeters of mercury, melting temperature >1800℃, molten pool temperature: 1750℃, after melting, the ingot is cooled to room temperature under vacuum in the furnace, the vacuum is broken, and it is taken out of the furnace.

6. The method for preparing a high-performance medical pure titanium anastomotic suture according to claim 1, characterized in that, The specific detection and analysis are as follows: the titanium ingot undergoes flaw detection to remove risers and shrinkage cavities, the surface of the titanium ingot is subjected to cold working and peeling treatment, and then samples are taken from the upper, middle, and lower sides of the titanium ingot side surface, as well as from the center of the titanium ingot end face, to analyze the gas and impurity composition; by mass percentage, the titanium ingot composition is controlled within the following range: O < 0.09%, N < 0.010%, H < 0.008%, C < 0.015%, Fe < 0.060%, Ti balance.

7. The method for preparing a high-performance medical pure titanium anastomotic suture according to claim 1, characterized in that, The fine cold-drawn wire deformation size range is: Φ0.8-1.0mm→Φ0.20-0.30mm, and the linear speed is: 1000-3000mm / minute.

8. The method for preparing a high-performance medical pure titanium anastomotic suture according to claim 1, characterized in that, The surface treatment of the pure titanium anastomotic suture involves ultrasonic cleaning of the suture surface with alcohol. The suture is fed by a suture feeding device and passes through an ultrasonic device filled with alcohol liquid. Under the action of ultrasonic waves, the liquid repeatedly cleans the surface of the suture. The suture is then continuously sent out from the outlet, quickly dried by hot air, and wound into the finished spool by a suture winding mechanism.

9. The high-performance medical pure titanium anastomotic suture prepared by the preparation method according to any one of claims 1-8.