Methods, control methods, systems and equipment for measuring magnetic resonance scanning labeling efficiency

By inserting a measurement subsequence within the delay time of the ASL sequence, the problem of excessively long ASL sequence scan time is solved, enabling fast and accurate measurement of labeling efficiency.

CN117314889BActive Publication Date: 2026-03-10SHANGHAI UNITED IMAGING HEALTHCARE
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-11-03
Publication Date
2026-03-10

AI Technical Summary

Technical Problem

In existing technologies, an additional measurement sequence is required for each ASL sequence scan, resulting in an excessively long scan time.

Method used

By segmenting the measurement sequence based on the delay time of the ASL sequence and inserting measurement sub-sequences within the delay time, the scan time is shortened.

Benefits of technology

This technology enables rapid measurement of labeling efficiency without affecting the calculation of the original ASL sequence CBF value, thus shortening the scan time.

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Abstract

This application discloses a method, control method, system, and device for measuring labeling efficiency in magnetic resonance imaging (MRI) scans. The measurement method includes: performing a measurement sequence scan on a target object; wherein the measurement sequence is used to measure the labeling efficiency of a corresponding arterial spin labeling sequence, the arterial spin labeling sequence including several labeling periods and imaging periods, with a delay time between the labeling periods and imaging periods; dividing the measurement sequence into corresponding measurement sub-sequences based on the delay duration of each delay time, and setting the measurement sub-sequences within their respective delay times; applying a first labeling pulse to the target object in each measurement sub-sequence to obtain a corresponding measurement image; obtaining the labeling efficiency of the first labeling pulse based on the measurement image, and using the labeling efficiency as the labeling measurement result of the arterial spin labeling sequence scan. By using the delay time of the ASL sequence to divide the measurement sequence into delay times, the overall scan time is shortened.
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Description

Technical Field

[0001] This application relates to the field of magnetic resonance scanning technology, and in particular to a method, control method, system and device for measuring magnetic resonance scanning labeling efficiency. Background Technology

[0002] Magnetic resonance imaging (MRI) is a relatively new technology compared to CT (Computed Tomography), providing excellent soft tissue contrast.

[0003] Magnetic resonance perfusion imaging (MRI) provides blood flow perfusion information, offering crucial data for the diagnosis of vascular diseases, tumors, and other conditions. Non-contrast MRI, also known as arterial spin labeling (ASL), is a drug-free MRI technique that directly obtains blood flow data reflecting tissue perfusion. Cerebral blood flow (CBF) is commonly used to assess tissue perfusion. Accurate measurement of labeling efficiency is necessary for accurate CBF calculation.

[0004] The current common method for measuring label efficiency is to first scan a sequence to measure label efficiency before scanning the subject's ASL sequence. Since an additional measurement sequence is required each time the subject undergoes an ASL sequence scan, the overall scanning time is relatively long. Summary of the Invention

[0005] The technical problem to be solved by this application is to overcome the defect in the prior art that an additional measurement sequence is required for each ASL sequence scan, resulting in an excessively long overall scan. This application provides a method, control method, system, device and medium for measuring magnetic resonance scanning labeling efficiency.

[0006] This application solves the above-mentioned technical problems through the following technical solution:

[0007] In a first aspect, a method for measuring magnetic resonance scanning labeling efficiency is provided, the method comprising:

[0008] Perform a measurement sequence scan on the object being scanned;

[0009] The measurement sequence is used to measure the labeling efficiency of the corresponding arterial spin labeling sequence. The arterial spin labeling sequence includes several labeling periods and imaging periods, with a delay time between the labeling periods and the imaging periods.

[0010] The measurement sequence is divided into corresponding measurement sub-sequences based on each delay time, and the measurement sub-sequences are set at the corresponding delay times;

[0011] In each of the measurement sub-sequences, a first marker pulse is applied to the scanned object to obtain the corresponding measurement image;

[0012] Wherein, the pulse parameters of the first labeling pulse and the second labeling pulse of the arterial spin labeling sequence are the same;

[0013] The labeling efficiency of the first labeling pulse is obtained based on the measured image, and the labeling efficiency is used as the labeling measurement result of the arterial spin labeling sequence scan.

[0014] Preferably, the step of dividing the measurement sequence into corresponding measurement subsequences based on each delay time includes:

[0015] Obtain the total delay duration for all the aforementioned delay times;

[0016] In response to the total delay being less than the measurement duration of the measurement sequence, the difference between the measurement duration and the total delay is calculated.

[0017] The measurement sequence is divided into a first measurement subsequence corresponding to the difference duration and a second measurement subsequence matching the delay time.

[0018] Preferably, the step of dividing the measurement sequence into corresponding measurement subsequences based on each delay time includes:

[0019] The shortest delay duration among all the aforementioned delay times is taken as the standard delay time;

[0020] The measurement sequence is divided into several third measurement subsequences based on the standard delay time, with the number of subsequences equal to the delay time. The remaining measurement duration of the measurement sequence is then used as the fourth measurement subsequence.

[0021] Secondly, a control method for magnetic resonance scanning is provided, the control method comprising:

[0022] The scanned object is scanned based on an arterial spin labeling sequence to obtain imaging label images and imaging control images;

[0023] Obtain the target labeling efficiency of the arterial spin labeling sequence;

[0024] The target labeling efficiency is obtained based on the measurement method of magnetic resonance scanning labeling efficiency described in the first aspect;

[0025] The target perfusion image of the scanned object is obtained by combining the imaging marker image, the imaging control image, and the target marker efficiency based on a preset imaging rule.

[0026] Preferably, the arterial spin labeling sequence includes several scan periods, and the control method further includes:

[0027] In response to the measurement sequence being completed before the arterial spin labeling sequence, it is determined whether the target labeling efficiency is greater than a preset efficiency threshold;

[0028] In response to the target labeling efficiency being less than the preset efficiency threshold, the labeling pulse parameters of the arterial spin labeling sequence are adjusted, and the remaining scan period is performed based on the adjusted labeling pulse parameters.

[0029] Preferably, the step of obtaining the target perfusion image of the scanned object based on the imaging marker image, the imaging control image, and the target marker efficiency according to a preset imaging rule includes:

[0030] A first perfusion image is obtained by processing the imaging marker image and the imaging control image;

[0031] The first perfusion image and the target marker efficiency are input into a preset reconstruction model, and the corresponding second perfusion image is output. The second perfusion image is used as the target perfusion image.

[0032] Thirdly, a measurement system for magnetic resonance scanning labeling efficiency is provided, the measurement system comprising a scanning module, a measurement allocation module, an image generation module, and an efficiency output module;

[0033] The scanning module is used to perform measurement sequence scanning on the object being scanned; wherein, the measurement sequence is used to measure the labeling efficiency of the corresponding arterial spin labeling sequence, the arterial spin labeling sequence includes several labeling periods and imaging periods, and a delay time is included between the labeling periods and the imaging periods;

[0034] The measurement allocation module is used to divide the measurement sequence into corresponding measurement sub-sequences based on each delay time, and set the measurement sub-sequences at the corresponding delay time;

[0035] The image generation module is used to apply a first labeling pulse to the scanned object in each measurement sub-sequence to obtain a corresponding measurement image; wherein the pulse parameters of the first labeling pulse and the second labeling pulse of the arterial spin labeling sequence are the same;

[0036] The efficiency output module is used to obtain the labeling efficiency of the first labeling pulse based on the measurement image, and use the labeling efficiency as the labeling measurement result of the arterial spin labeling sequence scan.

[0037] Fourthly, a control system for magnetic resonance scanning is provided, the control system including an image scanning module, an efficiency acquisition module, and an image output module;

[0038] The image scanning module is used to scan the object being scanned based on an arterial spin labeling sequence to obtain imaging label images and imaging control images;

[0039] The efficiency acquisition module is used to acquire the target labeling efficiency of the arterial spin labeling sequence;

[0040] The target labeling efficiency is obtained based on the magnetic resonance scanning labeling efficiency measurement system described in the third aspect;

[0041] The image output module is used to obtain the target perfusion image of the scanned object based on the imaging marker image, the imaging control image, and the target marker efficiency according to a preset imaging rule.

[0042] Fifthly, an electronic device is provided, including a memory, a processor, and a computer program stored in the memory and for running on the processor, wherein the processor executes the computer program to implement a method for measuring magnetic resonance scanning labeling efficiency as described in any one of the first aspects, or a method for controlling magnetic resonance scanning as described in any one of the second aspects.

[0043] In a sixth aspect, a computer storage medium is provided, on which a computer program is stored, wherein the computer program, when executed by a processor, implements a method for measuring magnetic resonance scanning labeling efficiency as described in any one aspect of the first aspect, or a method for controlling magnetic resonance scanning as described in any one aspect of the second aspect.

[0044] Based on common knowledge in the field, the above-mentioned preferred conditions can be combined arbitrarily to obtain various preferred embodiments of this application.

[0045] The positive and progressive effects of this application are as follows: by utilizing the delay time between multiple scans in the ASL sequence, the measurement sequence is partially or completely split and set in the delay time, thereby shortening the overall scan time of the ASL sequence and the measurement sequence, and realizing rapid measurement of magnetic resonance scanning labeling efficiency. Attached Figure Description

[0046] Figure 1 This is a flowchart of the method for measuring the magnetic resonance scanning labeling efficiency according to Embodiment 1 of this application;

[0047] Figure 2 This is a schematic diagram of the ASL sequence scanning method in the magnetic resonance scanning labeling efficiency measurement method of Embodiment 1 of this application;

[0048] Figure 3This is a schematic diagram of the measurement sequence in the magnetic resonance scanning labeling efficiency measurement method of Embodiment 1 of this application;

[0049] Figure 4 This is a time-series diagram of ASL sequences and measurement sequences in the prior art;

[0050] Figure 5 This is a timing diagram of the measurement sequence in the magnetic resonance scanning labeling efficiency measurement method of Embodiment 1 of this application;

[0051] Figure 6 This is a timing diagram of the ASL sequence and the measurement sequence in the magnetic resonance scanning labeling efficiency measurement method of Embodiment 1 of this application;

[0052] Figure 7 This is the first flowchart of step S102 in the method for measuring magnetic resonance scanning labeling efficiency according to Embodiment 1 of this application;

[0053] Figure 8 This is the second flowchart of step S102 in the method for measuring magnetic resonance scanning labeling efficiency according to Embodiment 1 of this application;

[0054] Figure 9 This is a flowchart of the magnetic resonance scanning control method according to Embodiment 2 of this application;

[0055] Figure 10 This is a flowchart of step S203 in the magnetic resonance scanning control method of Embodiment 2 of this application;

[0056] Figure 11 This is a schematic diagram of the imaging marker image, imaging control image, and first perfusion image of the magnetic resonance scanning control method of Embodiment 2 of this application;

[0057] Figure 12 This is a schematic diagram of the module of the magnetic resonance scanning labeling efficiency measurement system of Embodiment 3 of this application;

[0058] Figure 13 This is a schematic diagram of the control system for magnetic resonance scanning according to Embodiment 4 of this application;

[0059] Figure 14 This is a schematic diagram of the hardware structure of the electronic device according to Embodiment 5 of this application. Detailed Implementation

[0060] The present application is further illustrated below by way of embodiments, but this does not limit the present application to the scope of the embodiments described.

[0061] In the description of this application, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined as "first," "second," or "third" may explicitly or implicitly include one or more of that feature. In the description of this application, "multiple" means two or more, unless otherwise explicitly specified.

[0062] Example 1

[0063] This embodiment provides a method for measuring the labeling efficiency of magnetic resonance scanning, such as... Figure 1 As shown, the measurement method includes:

[0064] S101. Perform a measurement sequence scan on the object being scanned;

[0065] The measurement sequence is used to measure the labeling efficiency of the corresponding arterial spin labeling sequence, wherein the arterial spin labeling sequence includes several labeling periods and imaging periods, and a delay time is included between the labeling periods and the imaging periods;

[0066] S102. Divide the measurement sequence into corresponding measurement sub-sequences based on each delay time, and set the measurement sub-sequences at the corresponding delay times;

[0067] S103. Apply a first marker pulse to the scanned object in each measurement sub-sequence to obtain the corresponding measurement image;

[0068] Wherein, the pulse parameters of the first labeling pulse and the second labeling pulse of the arterial spin labeling sequence are the same;

[0069] S104. Based on the measured image, obtain the labeling efficiency of the first labeling pulse, and use the labeling efficiency as the labeling measurement result of the arterial spin labeling sequence scan.

[0070] In this scheme, the measurement sequence is allocated based on the delay time. Since a single delay time is insufficient to acquire a complete measurement sequence, the allocated measurement sub-sequences are inserted into the corresponding delay times to acquire multiple first-label pulses and corresponding measurement images. Simultaneous measurement of CBF using the ASL sequence and measurement of label efficiency using the measurement sequence do not affect the calculation of the original ASL sequence's CBF value; the CBF calculation model remains unchanged due to simultaneous measurement of label efficiency. Therefore, the measurement of label efficiency does not affect the original labeling and perfusion results. By placing the control chart for measuring label efficiency into the control group and perfusion group respectively, the perfusion map obtained by subtracting the control group and label group removes the labeling influence of measuring label efficiency. Therefore, the CBF calculation model remains unchanged due to simultaneous measurement of label efficiency. The delay time of the original ASL sequence also remains unchanged. Figure 2 It is a scan of the ASL perfusion imaging region and Figure 3 This is a schematic diagram of the measurement marker efficiency region. The two are completely unrelated in spatial location and therefore do not affect each other. For example, as shown... Figure 2 As shown, the labeled area in the figure represents the region where a second labeling pulse is applied to the scanned object during the labeling period in the arterial spin labeling sequence, and the perfusion imaging area represents the acquisition area during the imaging period in the arterial spin labeling sequence; as Figure 3 As shown in the figure, the marked band represents the region where a first marked pulse is applied to the scanned object in the measurement sequence, and the measurement area is the measurement region of the measurement image in the measurement sequence. The pulse parameters of the first and second marked pulses are the same, including the same position in the marked area and acquisition area of ​​the scanned object. Optionally, the pulse intensities of the first and second marked pulses are the same, and the marking time of the first marked pulse in the measurement sequence is shorter. For example, as... Figure 4 As shown, in existing magnetic resonance imaging (MRI) systems, the entire measurement sequence is scanned first, followed by the ASL sequence. The entire MRI scan cycle is relatively long. Furthermore, the arterial spin labeling sequence, as shown in the diagram, has several unutilized delay times between pairs of labeling and imaging periods, between the labeling period (represented by the control and labeling modules on the left) and the imaging period (represented by the ASL acquisition module on the right). Figure 5 The diagram shows the timing sequence of the measurement sequence in this scheme. In the measurement sequence, a first marker pulse with the same pulse parameters as the ASL sequence is applied through the control module and marker module. This is used to generate the control chart and marker chart corresponding to the measurement sequence. The measurement acquisition module then acquires the control chart and marker chart corresponding to the measurement sequence to obtain the corresponding measurement image. Figure 6As shown, in this scheme, the measurement sequence is set based on the delay time in the ASL sequence. The magnetic resonance scanning system executes the measurement sub-sequence during the delay time between the labeling period and the imaging period of the ASL sequence, shortening the entire magnetic resonance scanning cycle. The measurement image acquisition module obtains the measurement image from the measurement sequence scan based on the control module and the labeling module. When the region of interest to be scanned is the brain, the label is injected into the body of the scanned object, and the scanned object is scanned based on the measurement sequence using magnetic resonance imaging. 2D GRE (Gradient Echo Magnetic Resonance Imaging) imaging is performed at the blood vessels. The measurement sequence is divided into several measurement sub-sequences interspersed in the acquisition sequence during the arterial self-labeled sequence scan. Each measurement sub-sequence obtains a pair of control group images and label group images. The labeling efficiency corresponding to the measurement image is calculated by using the label group images and control group images, which serves as the labeling efficiency measurement result of the arterial self-labeled sequence, so as to enable the arterial self-labeled sequence to better complete CBF perfusion imaging. The ASL sequence, combined with the measurement sequence as illustrated in the diagram above, is repeatedly scanned until all corresponding data acquisition is complete. All data includes perfusion data from the ASL sequence and labeling efficiency measurements from the measurement sequence. The measurement data is then processed to obtain the labeling efficiency value. This measured labeling efficiency value is applied to the model calculation for ASL sequence perfusion imaging to obtain a more accurate CBF value. By matching the delay time of the measurement sub-sequence of the measurement sequence with the arterial spin-labeled sequence, CBF perfusion imaging and labeling efficiency measurements of the arterial spin-labeled sequence can be completed simultaneously in the shortest possible time, improving the measurement efficiency of magnetic resonance perfusion imaging and the flexibility of measurement sequence settings.

[0071] As a feasible approach, such as Figure 7 As shown, step S102 includes:

[0072] S1021. Obtain the total delay duration of all the aforementioned delay times;

[0073] S1022. In response to the total delay duration being less than the measurement duration of the measurement sequence, the difference between the measurement duration and the total delay duration is calculated.

[0074] S1023. Divide the measurement sequence into a first measurement subsequence corresponding to the difference duration and a second measurement subsequence matching the delay time.

[0075] In this scheme, based on the total duration of the delay time, each delay time is utilized to the maximum extent. The measurement sequence is assigned a corresponding measurement sub-sequence according to each delay time, thus interleaving the measurement sequence with the arterial spin labeling sequence. For example, if the ASL sequence includes 10 periods, then there are 9 corresponding delay times. The difference duration is calculated based on the total delay duration of these 9 delay times and the measurement duration of the measurement sequence, and is used as the first measurement sub-sequence. The portion of the measurement sequence after removing the difference duration is assigned as 9 corresponding second measurement sub-sequences based on the 9 delay times. For example, the first measurement sub-sequence, which serves as the difference duration, begins before the arterial spin labeling sequence, so that the measurement sequence is completed before the arterial spin labeling sequence. Depending on actual operational needs, the start time of the measurement sequence can also be appropriately advanced so that the measurement sequence is completed earlier than the arterial spin labeling sequence, for example, by reducing the number of second measurement sub-sequences and adding the extra second measurement sub-sequences to the first measurement sub-sequence. This shortens the extra scan time occupied by the measurement sequence beyond the arterial spin labeling sequence, improving the efficiency of the measurement sequence.

[0076] As a feasible approach, such as Figure 8 As shown, step S102 includes:

[0077] S1024. Obtain the shortest standard delay duration among all the aforementioned delay times;

[0078] S1025. The measurement sequence is divided into several third measurement sub-sequences with the same number of delay times based on the standard delay duration, and the remaining measurement duration of the measurement sequence is used as the fourth measurement sub-sequence.

[0079] In this scheme, the shortest standard delay duration is selected from the delay times, and the measurement sequence is quickly allocated based on the standard delay duration. For example, if the ASL sequence includes 10 periods, then there are 9 corresponding delay times. The 5th delay time has the shortest duration, so it is used as the standard delay duration. The measurement sequence is then divided into 9 third measurement subsequences with corresponding standard delay durations. If there is any remaining measurement duration in the measurement sequence, it is used as a fourth measurement subsequence. For example, if the standard delay duration is T... y The total duration of the measurement sequence is T. c The duration of the third measurement subsequence is T3, and the duration of the fourth measurement subsequence is T4. Then T4 = T c -9×T3, T y =T3; By determining the standard delay duration to reduce the amount of computation allocated, the extra scan time occupied by the measurement sequence in addition to the arterial spin labeling sequence is shortened, while improving the working efficiency of the measurement sequence.

[0080] As an achievable approach, in response to a total delay duration exceeding the measurement duration of the measurement sequence, the temporal order of each delay time within the arterial spin label sequence is sorted, and the measurement sequence is sequentially assigned to corresponding measurement sub-sequences based on the earliest occurring delay time, until the entire measurement sequence is assigned.

[0081] The magnetic resonance scanning labeling efficiency measurement method provided in this embodiment shortens the overall scanning time of the ASL sequence and the measurement sequence by utilizing the delay time between multiple scans in the ASL sequence and setting part or all of the measurement sequence in the delay time, thereby improving the rapid measurement of magnetic resonance scanning labeling efficiency.

[0082] Example 2

[0083] This embodiment provides a method for controlling magnetic resonance scanning, such as... Figure 9 As shown, the control method includes:

[0084] S201. Scan the object being scanned based on arterial spin labeling sequences to obtain imaging label images and imaging control images;

[0085] S202. Obtain the target labeling efficiency of the arterial spin labeling sequence;

[0086] The target labeling efficiency is obtained based on the magnetic resonance scanning labeling efficiency measurement method described in Example 1;

[0087] S203. The target perfusion image of the scanned object is obtained by combining the imaging marker image, the imaging control image, and the target marker efficiency based on a preset imaging rule.

[0088] In this scheme, the target labeling efficiency is obtained through the measurement method of magnetic resonance scanning labeling efficiency. This enables the measurement sequence to be completed simultaneously with the arterial spin labeling sequence, shortening the total duration of the measurement sequence and the arterial spin labeling sequence, reducing the overall working time of the magnetic resonance scanning sequence, and improving scanning efficiency.

[0089] As one possible implementation, the arterial spin labeling sequence includes several scan periods, and the control method further includes:

[0090] In response to the measurement sequence being completed before the arterial spin labeling sequence, it is determined whether the labeling efficiency is greater than a preset efficiency threshold;

[0091] In response to the target labeling efficiency being less than the preset efficiency threshold, the labeling pulse parameters of the arterial spin labeling sequence are adjusted, and the remaining scan period is performed based on the adjusted labeling pulse parameters.

[0092] In this scheme, the target labeling efficiency is obtained by using the measurement sequence that is completed first. When the target labeling efficiency cannot meet the efficiency threshold, the labeling pulse parameters of the arterial spin labeling sequence are adjusted in real time to improve the efficiency of magnetic resonance imaging while ensuring the imaging quality of magnetic resonance imaging.

[0093] As one possible approach, in response to the target labeling efficiency being less than the preset efficiency threshold, image quality identification is performed on the imaging control image and imaging label image corresponding to the completed scanning period of the arterial spin labeling sequence; in response to the image quality of the acquired imaging control image and imaging label image not meeting the preset image quality, the magnetic resonance scanning system is controlled to rescan the completed scanning period of the arterial spin labeling sequence based on the adjusted labeling pulse parameters to ensure the imaging quality of the magnetic resonance scan.

[0094] As a feasible approach, such as Figure 10 As shown, step S203 includes:

[0095] S2031. Based on the imaging marker image and the imaging control image, a first perfusion image is obtained;

[0096] S2032. Input the first perfusion image and the target marker efficiency into a preset reconstruction model, output the corresponding second perfusion image, and use the second perfusion image as the target perfusion image.

[0097] In this approach, paired imaging marker images and imaging control images are obtained by scanning the same region of interest using arterial spin labeling sequences. For example, ... Figure 11 As shown, the left image is the imaging label image (Label), the middle image is the imaging control image (Control), and the right image is the first perfusion image (Sub). The first perfusion image is obtained by subtracting the corresponding imaging label image and imaging control image. The first perfusion image is calibrated and reconstructed by adjusting the efficiency of the target label. For example, the preset reconstruction model includes an image registration model, an image denoising model, an image enhancement model, or an image reconstruction model, etc. Preferably, the model architecture of the preset reconstruction model is a deep convolutional neural network. This achieves high-quality imaging of magnetic resonance imaging and improves the efficiency of magnetic resonance imaging.

[0098] The magnetic resonance scanning control method provided in this solution achieves the target labeling efficiency by measuring the labeling efficiency of magnetic resonance scanning. This allows the measurement sequence to be completed simultaneously with the arterial spin labeling sequence, shortening the total duration of the measurement sequence and the arterial spin labeling sequence. This improves the efficiency of magnetic resonance imaging while ensuring the imaging quality of the magnetic resonance scan.

[0099] Example 3

[0100] This embodiment provides a magnetic resonance scanning labeling efficiency measurement system 100, such as... Figure 12 As shown, the measurement system 100 includes a scanning module 101, a measurement allocation module 102, an image generation module 103, and an efficiency output module 104;

[0101] The scanning module 101 is used to perform a measurement sequence scan on the object being scanned; wherein, the measurement sequence is used to measure the corresponding arterial spin labeling sequence, the arterial spin labeling sequence includes several labeling periods and imaging periods, and a delay time is included between the labeling periods and the imaging periods;

[0102] The measurement allocation module 102 is used to divide the measurement sequence into corresponding measurement sub-sequences based on each delay time, and set the measurement sub-sequences at the corresponding delay time;

[0103] The image generation module 103 is used to apply a first labeling pulse to the scanned object in each measurement sub-sequence to obtain a corresponding measurement image; wherein the pulse parameters of the first labeling pulse are the same as those of the second labeling pulse of the arterial spin labeling sequence.

[0104] The efficiency output module 104 is used to obtain the labeling efficiency of the first labeling pulse based on the measurement image, and use the labeling efficiency as the labeling measurement result of the arterial spin labeling sequence scan.

[0105] In one possible implementation, the measurement allocation module 102 includes a delay duration statistics unit and an allocation unit;

[0106] The delay duration statistics unit is used to obtain the total delay duration of all the delay times;

[0107] The allocation unit is configured to calculate the difference between the measurement duration and the total delay duration in response to the total delay duration being less than the measurement duration of the measurement sequence.

[0108] The measurement sequence is divided into a first measurement subsequence corresponding to the difference duration and a second measurement subsequence matching the delay time.

[0109] As one possible approach, the delay duration statistics unit is also used to obtain the shortest delay time among all the delay times as the standard delay time;

[0110] The allocation unit is further configured to divide the measurement sequence into several third measurement sub-sequences with the same number of delay times based on the standard delay time, and the remaining measurement duration of the measurement sequence is used as a fourth measurement sub-sequence.

[0111] It should be noted that the implementation principle of the magnetic resonance scanning labeling efficiency measurement system in this embodiment is the same as that of the magnetic resonance scanning labeling efficiency measurement method in Embodiment 1, so it will not be described again here.

[0112] The magnetic resonance scanning labeling efficiency measurement system provided in this embodiment shortens the overall scanning time of the ASL sequence and the measurement sequence by utilizing the delay time between multiple scans in the ASL sequence and setting part or all of the measurement sequence in the delay time, thereby improving the rapid measurement of magnetic resonance scanning labeling efficiency.

[0113] Example 4

[0114] This embodiment provides a magnetic resonance scanning control system 200, such as... Figure 13 As shown, the control system 200 includes an image scanning module 201, an efficiency acquisition module 202, and an image output module 203;

[0115] The image scanning module 201 is used to scan the object being scanned based on an arterial spin labeling sequence to acquire labeled images and control images.

[0116] The efficiency acquisition module 202 is used to acquire the labeling efficiency of the arterial spin labeling sequence;

[0117] The labeling efficiency is obtained based on the magnetic resonance scanning labeling efficiency measurement system described in Example 3;

[0118] The image output module 203 is used to obtain the target perfusion image of the scanned object based on the marked image, control image and marking efficiency according to a preset imaging rule.

[0119] In one possible manner, the arterial spin labeling sequence includes several scan periods, and the control system 200 further includes a verification module and an adjustment module;

[0120] The verification module is used to determine whether the labeling efficiency is greater than a preset efficiency threshold in response to the measurement sequence being completed before the arterial spin labeling sequence.

[0121] The adjustment module is used to adjust the labeling pulse parameters of the arterial spin labeling sequence in response to the labeling efficiency being less than the preset efficiency threshold.

[0122] In one possible manner, the image output module 203 is further configured to process the labeled image and the control image to obtain a first perfusion image; input the first perfusion image and the labeled efficiency into a preset reconstruction model, output a corresponding second perfusion image, and use the second perfusion image as the target perfusion image.

[0123] It should be noted that the implementation principle of the magnetic resonance scanning control system in this embodiment is the same as that of the magnetic resonance scanning control method in Embodiment 2, so it will not be described again here.

[0124] The magnetic resonance scanning control system provided in this embodiment achieves the target labeling efficiency obtained by the magnetic resonance scanning labeling efficiency measurement method, and completes the measurement sequence work while executing the arterial spin labeling sequence. This shortens the total time of the measurement sequence and the arterial spin labeling sequence, improves the efficiency of magnetic resonance scanning imaging, and ensures the imaging quality of magnetic resonance scanning.

[0125] Example 5

[0126] like Figure 14 The diagram shown is a structural schematic of an electronic device provided in Embodiment 3 of this application. It includes a memory, a processor, and a computer program stored in the memory and used to run on the processor. When the processor executes the computer program, it implements the method for measuring the magnetic resonance scanning labeling efficiency described in Embodiment 1, or the magnetic resonance scanning control method described in Embodiment 2. Figure 14 The electronic device 30 shown is merely an example and should not impose any limitations on the functionality and scope of use of the embodiments of this application.

[0127] The electronic device 30 may be in the form of a general-purpose computing device, such as a server device. The components of the electronic device 30 may include, but are not limited to: at least one processor 31, at least one memory 32, and a bus 33 connecting different system components (including memory 32 and processor 31).

[0128] Bus 33 includes a data bus, an address bus, and a control bus.

[0129] The memory 32 may include volatile memory, such as random access memory (RAM) 321 and / or cache memory 322, and may further include read-only memory (ROM) 323.

[0130] The memory 32 may also include a program / utility 325 having a set (at least one) of program modules 324, including but not limited to: an operating system, one or more application programs, other program modules, and program data, each or some combination of these examples may include an implementation of a network environment.

[0131] The processor 31 executes various functional applications and data processing by running computer programs stored in the memory 32, such as the method for measuring magnetic resonance scanning labeling efficiency described in Embodiment 1 of this application, or the method for controlling magnetic resonance scanning described in Embodiment 2.

[0132] Electronic device 30 can also communicate with one or more external devices 34 (e.g., keyboard, pointing device, etc.). This communication can be performed via input / output (I / O) interface 35. Furthermore, the model-generated device 30 can also communicate with one or more networks (e.g., local area network (LAN), wide area network (WAN), and / or public network, such as the Internet) via network adapter 36. As shown, network adapter 36 communicates with other modules of the model-generated device 30 via bus 33. It should be understood that, although not shown in the figure, other hardware and / or software modules can be used in conjunction with the model-generated device 30, including but not limited to: microcode, device drivers, redundant processors, external disk drive arrays, RAID (disk array) systems, tape drives, and data backup storage systems.

[0133] It should be noted that although the units / modules or sub-units / modules of the electronic device are mentioned in the detailed description above, this division is merely exemplary and not mandatory. In fact, according to the embodiments of this application, the features and functions of two or more units / modules described above can be embodied in one unit / module. Conversely, the features and functions of one unit / module described above can be further divided and embodied by multiple units / modules.

[0134] Example 6

[0135] This application also provides a computer-readable storage medium having a computer program stored thereon, which, when executed by a processor, implements the method for measuring the magnetic resonance scanning labeling efficiency described in Embodiment 1, or the method for controlling magnetic resonance scanning described in Embodiment 2.

[0136] The readable storage medium may be more specifically adopted, including but not limited to: portable disk, hard disk, random access memory, read-only memory, erasable programmable read-only memory, optical storage device, magnetic storage device, or any suitable combination thereof.

[0137] In a possible implementation, this application may also be implemented as a program product comprising program code, which, when the program product is run on a terminal device, causes the terminal device to execute the measurement method for magnetic resonance scanning label efficiency described in Embodiment 1, or the control method for magnetic resonance scanning described in Embodiment 2.

[0138] The program code for executing this application can be written in any combination of one or more programming languages. The program code can be executed entirely on the user device, partially on the user device, as a standalone software package, partially on the user device and partially on a remote device, or entirely on a remote device.

[0139] While specific embodiments of this application have been described above, those skilled in the art should understand that these are merely illustrative examples, and the scope of protection of this application is defined by the appended claims. Those skilled in the art can make various changes or modifications to these embodiments without departing from the principles and essence of this application, but all such changes and modifications fall within the scope of protection of this application.

Claims

1. A method of measuring the efficiency of a magnetic resonance scan marker, characterized by, The measurement method comprises: performing a measurement sequence scan on a scanned object; wherein the measurement sequence is used to measure the labeling efficiency of a corresponding arterial spin labeling sequence, the arterial spin labeling sequence comprising a plurality of labeling periods and imaging periods, the labeling periods and the imaging periods comprising a delay time therebetween; dividing the measurement sequence into corresponding measurement sub-sequences based on each of the delay times, and setting the measurement sub-sequences at the corresponding delay times; applying a first labeling pulse to the scanned object in each of the measurement sub-sequences to obtain a corresponding measurement image; wherein the first labeling pulse and a second labeling pulse of the arterial spin labeling sequence have the same pulse parameters, and the measurement region of the measurement image is different from the spatial position of the acquisition region in the imaging period; obtaining the labeling efficiency of the first labeling pulse based on the measurement image, and taking the labeling efficiency as the labeling measurement result of the arterial spin labeling sequence scan.

2. The method of measuring magnetic resonance scan labeling efficiency of claim 1, wherein, The step of dividing the measurement sequence into corresponding measurement sub-sequences based on each of the delay times comprises: obtaining the total delay time of all the delay times; in response to the total delay time being less than the measurement time of the measurement sequence, calculating the difference time between the measurement time and the total delay time; dividing the measurement sequence into a first measurement sub-sequence corresponding to the difference time, and a second measurement sub-sequence matching the delay times.

3. The method of measuring magnetic resonance scan labeling efficiency of claim 1, wherein, The step of dividing the measurement sequence into corresponding measurement sub-sequences based on each of the delay times comprises: obtaining the shortest delay time among all the delay times as a standard delay time; dividing the measurement sequence into a plurality of third measurement sub-sequences based on the standard delay time, the number of the third measurement sub-sequences being the same as the number of the delay times, and the remaining measurement time of the measurement sequence being a fourth measurement sub-sequence.

4. A method of controlling a magnetic resonance scan, characterized by, The control method comprises: performing an arterial spin labeling sequence scan on a scanned object to obtain an imaging labeling image and an imaging control image; obtaining a target labeling efficiency of the arterial spin labeling sequence; wherein the target labeling efficiency is obtained based on the magnetic resonance scan labeling efficiency measurement method of any one of claims 1 to 3; obtaining a target perfusion image of the scanned object based on the imaging labeling image, the imaging control image, and the target labeling efficiency according to a preset imaging rule.

5. A method of controlling a magnetic resonance scan as claimed in claim 4, characterized in that, The arterial spin labeling sequence comprises a plurality of scanning periods, and the control method further comprises: in response to the measurement sequence being completed before the arterial spin labeling sequence, determining whether the target labeling efficiency is greater than a preset efficiency threshold; in response to the target labeling efficiency being less than the preset efficiency threshold, adjusting the labeling pulse parameters of the arterial spin labeling sequence, and performing the remaining scanning periods based on the adjusted labeling pulse parameters.

6. The method of controlling a magnetic resonance scan of claim 4, wherein, The step of obtaining a target perfusion image of the scanned object based on the imaging labeling image, the imaging control image, and the target labeling efficiency according to a preset imaging rule comprises: processing the imaging labeling image and the imaging control image to obtain a first perfusion image; The first perfusion image and the target labeling efficiency are input into a preset reconstruction model, and a corresponding second perfusion image is output as the target perfusion image.

7. A system for measuring the efficiency of a magnetic resonance scan marker, characterized by, The measurement system comprises a scanning module, a measurement distribution module, an image generation module and an efficiency output module; The scanning module is configured to perform measurement sequence scanning on the scanned object; wherein the measurement sequence is used to measure the labeling efficiency of a corresponding arterial spin labeling sequence, the arterial spin labeling sequence comprises a plurality of labeling periods and imaging periods, and the delay time is included between the labeling period and the imaging period; The measurement distribution module is configured to divide the measurement sequence into corresponding measurement sub-sequences based on each delay time, and set the measurement sub-sequences at the corresponding delay times; The image generation module is configured to apply a first labeling pulse to the scanned object in each measurement sub-sequence to obtain a corresponding measurement image; Wherein, the pulse parameters of the first labeling pulse and the second labeling pulse of the arterial spin labeling sequence are the same, and the measurement region of the measurement image is different from the spatial position of the acquisition region in the imaging period; The efficiency output module is configured to obtain the labeling efficiency of the first labeling pulse based on the measurement image, and take the labeling efficiency as the labeling measurement result of the arterial spin labeling sequence scanning.

8. A control system for a magnetic resonance scan, characterized in that The control system comprises an image scanning module, an efficiency acquisition module and an image output module; The image scanning module is configured to scan the scanned object based on the arterial spin labeling sequence to obtain an imaging labeling image and an imaging control image; The efficiency acquisition module is configured to obtain a target labeling efficiency of the arterial spin labeling sequence; Wherein, the target labeling efficiency is obtained based on the magnetic resonance scanning labeling efficiency measurement system of claim 7; The image output module is configured to obtain a target perfusion image of the scanned object based on the imaging labeling image, the imaging control image and the target labeling efficiency based on a preset imaging rule.

9. An electronic device comprising a memory, a processor, and a computer program stored on the memory for running on the processor, characterized in that, The processor executes the computer program to implement the magnetic resonance scanning labeling efficiency measurement method of any one of claims 1-3, or the magnetic resonance scanning control method of any one of claims 4-6.

10. A computer storage medium having stored thereon a computer program, characterized in that The computer program is executed by the processor to implement the magnetic resonance scanning labeling efficiency measurement method of any one of claims 1-3, or the magnetic resonance scanning control method of any one of claims 4-6.

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