Traditional Chinese medicine composition, preparation and use thereof

Abstract

The application discloses a traditional Chinese medicine composition, which comprises the following raw materials: shengteng, honeysuckle, chrysanthemum, peppermint, forsythia, platycodon, radix peucedani, anemarrhena, radix pini, radix styracis, scabrousfruit, calcined turtle, artemisia, apricot kernel, gypsum, ephedra, licorice, ophiopogon, radix scrophulariae, radix bupleuri. The application further discloses a preparation containing the traditional Chinese medicine composition and application of the traditional Chinese medicine composition in preparation of a medicine for treating viral pneumonia. The traditional Chinese medicine composition has a rapid relieving effect on high fever and cough caused by viral pneumonia, can effectively treat viral pneumonia, and relieve the pain of patients. The safety and effectiveness of the traditional Chinese medicine composition are proved through years of clinical practice.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine, and particularly relates to traditional Chinese medicine compositions, their preparations, and uses. Background Technology

[0002] Viral pneumonia is an inflammation of the lungs caused by the downward spread of upper respiratory tract viral infections. It can occur year-round, but is most prevalent in winter and spring. There are approximately twenty different viruses that can cause viral pneumonia, including influenza virus, adenovirus, respiratory syncytial virus, rhinovirus, Haemophilus parainfluenzae virus, coronavirus, cytomegalovirus, and Epstein-Barr virus (EBV). Patients can be infected with more than one virus simultaneously and often develop secondary bacterial infections; patients with weakened immune systems often also develop secondary fungal infections. Respiratory viruses can be transmitted rapidly and widely through droplets and direct contact. Viral pneumonia typically has a rapid onset and progression. The main clinical symptoms are fever and cough. As the disease progresses, complications such as persistent high fever, chest tightness, difficulty breathing, lung abscess, pleural effusion, and atelectasis may occur. In severe cases, it can lead to pulmonary insufficiency, shock, respiratory failure, and even multiple organ failure, ultimately endangering life. Avian influenza virus and SARS virus can cause severe pneumonia with a high mortality rate, especially in elderly, frail, and immunocompromised patients. Timely diagnosis and treatment are crucial for viral pneumonia.

[0003] Currently, the most common laboratory method for confirmation is the detection of viral nucleic acid via reverse transcription polymerase chain reaction (RT-PCR) of respiratory secretions. Antiviral drugs are selected based on the drug sensitivity of the infecting virus. Commonly used drugs include ribavirin and oseltamivir; in the absence of a corresponding sensitive drug, supportive treatment is primarily administered. Convalescent plasma has been used for patients with viral pneumonia caused by SARS and MERS, and its application in the early stages of the disease can improve prognosis.

[0004] Traditional Chinese medicine (TCM) believes that the main cause of viral pneumonia is exposure to pathogenic heat. Pathogenic heat most easily invades the lung system, causing respiratory diseases. The theory that exposure to pathogenic heat leads to viral pneumonia is similar to the modern epidemiological explanation of the disease's pathogenesis. TCM believes that "when the body's vital energy is strong, pathogenic factors cannot invade." Therefore, in treating viral pneumonia, TCM not only advocates expelling pathogenic factors but also emphasizes supporting and strengthening the patient's own vital energy to achieve the effect of the body's resistance overcoming the pathogenic factors. Summary of the Invention

[0005] Based on the above-mentioned technical problems, the present invention combines and modifies traditional prescriptions to obtain a traditional Chinese medicine composition and preparation that has a better therapeutic effect on viral pneumonia.

[0006] The specific solution of this invention is as follows:

[0007] One of the objectives of this invention is to provide a traditional Chinese medicine composition comprising the following ingredients: raw vine, honeysuckle, chrysanthemum, peppermint, forsythia, platycodon, angelica dahurica, anemarrhena, aster, stemona, burdock seed, processed turtle shell, artemisia annua, apricot kernel, gypsum, ephedra, licorice, ophiopogon japonicus, scutellaria baicalensis, and bupleurum chinense.

[0008] The functions of each component in this traditional Chinese medicine composition are as follows:

[0009] Raw vine: dispels wind and releases the exterior, relieves cough and resolves phlegm, promotes qi circulation and relieves pain;

[0010] Honeysuckle: Clears heat and detoxifies, treats wind-related ailments, nourishes blood, and quenches thirst;

[0011] Forsythia: dispels wind-heat, clears heat and detoxifies, reduces swelling and dissipates nodules;

[0012] Ephedra: Induces sweating to relieve exterior syndromes, promotes lung function to relieve asthma, and promotes diuresis to reduce edema;

[0013] Stemona japonica: moistens lung qi, resolves phlegm and relieves cough;

[0014] Gypsum: Clears heat and drains fire, relieves irritability and quenches thirst;

[0015] Aster: It disperses and clears heat, resolves phlegm and relieves cough;

[0016] Scutellaria baicalensis: clears heat and dries dampness, drains fire and detoxifies, and stops bleeding;

[0017] Chrysanthemum: dispels wind-heat, calms the liver and improves eyesight, clears heat and detoxifies;

[0018] Peppermint: Disperses wind-heat, clears the head and eyes, soothes the throat, promotes rash eruption, and soothes the liver and regulates qi.

[0019] Platycodon grandiflorus: clears the lungs, soothes the throat, eliminates phlegm, and drains pus;

[0020] Bupleurum chinense: relieves exterior syndromes and dispels cold, soothes the liver and harmonizes the stomach;

[0021] Peucedanum praeruptorum: Clears wind-heat, regulates lung qi, and eliminates excess heat;

[0022] Burdock seed: Clears stagnant heat in the liver meridian and regulates wind-heat in the lungs;

[0023] Ophiopogon japonicus: Nourishes Yin and generates fluids, moistens the lungs and clears the heart, soothes the throat, and relieves fatigue;

[0024] Almonds: relieve phlegm and muscle tension, dispel wind and cold;

[0025] Anemarrhena asphodeloides: Clears kidney fire, moistens lungs and nourishes yin;

[0026] Artemisia annua: relieves summer heat and fever, cools the blood and stops bleeding;

[0027] Roasted turtle shell: Nourishes Yin and clears heat, subdues Yang and extinguishes wind, softens hardness and dissipates nodules;

[0028] Licorice: Clears heat and detoxifies, tonifies the spleen and replenishes qi, moistens the lungs and resolves phlegm, relieves spasms and pain, and harmonizes the effects of other herbs.

[0029] The traditional Chinese medicine composition of this invention uses raw vine, ephedra, honeysuckle, forsythia, prepared turtle shell, and artemisia annua as the principal herbs, which can induce sweating to relieve exterior syndromes, clear lung heat, nourish yin and relieve fever. Gypsum, anemarrhena, angelica, aster, burdock seed, stemona, chrysanthemum, scutellaria, platycodon, bupleurum, and peppermint as the assistant herbs, which can clear heat and dispel pathogens, nourish yin and moisten dryness, and relieve cough and resolve phlegm. Apricot kernel and ophiopogon are the adjuvant herbs, assisting the principal herbs in moistening the lungs, relieving asthma, and generating fluids. Licorice is the guiding herb, relieving cough and asthma while harmonizing the other herbs and detoxifying their toxicity.

[0030] Preferably, the ingredients, by weight, include the following: 5-50 parts of raw vine, 5-50 parts of honeysuckle, 5-50 parts of chrysanthemum, 5-50 parts of peppermint, 5-50 parts of forsythia, 5-50 parts of platycodon, 5-50 parts of angelica, 5-50 parts of anemarrhena, 5-50 parts of aster, 5-50 parts of stemona, 5-50 parts of burdock, 5-50 parts of processed turtle shell, 5-50 parts of artemisia, 5-50 parts of apricot kernel, 5-50 parts of gypsum, 5-50 parts of ephedra, 5-50 parts of licorice, 5-50 parts of ophiopogon, 5-50 parts of scutellaria, and 5-50 parts of bupleurum.

[0031] Preferably, the ingredients, by weight, include the following: 10-30 parts of raw vine, 10-30 parts of honeysuckle, 10-30 parts of chrysanthemum, 10-30 parts of peppermint, 10-30 parts of forsythia, 10-30 parts of platycodon, 10-30 parts of angelica dahurica, 10-30 parts of anemarrhena asphodeloides, 10-30 parts of stemona japonica, 10-30 parts of burdock seed, 10-30 parts of processed turtle shell, 10-30 parts of artemisia annua, 10-30 parts of apricot kernel, 10-30 parts of gypsum, 10-30 parts of ephedra, 10-30 parts of licorice, 10-30 parts of ophiopogon japonicus, 10-30 parts of scutellaria baicalensis, and 10-30 parts of bupleurum chinense.

[0032] The second objective of this invention is to provide a pharmaceutical preparation comprising any of the above-mentioned traditional Chinese medicine compositions.

[0033] Preferably, it also includes pharmaceutically acceptable excipients.

[0034] Preferably, the pharmaceutical preparation includes any one of the following: ointment, decoction, tablet, granule, capsule, powder, pill, drop, tea, or mixture. In particular, preparation as granules and capsules facilitates storage, carrying, and administration.

[0035] Preferably, the pharmaceutical preparation is selected from ointments.

[0036] Preferably, the ointment is an extract, and its preparation method includes the following steps: (1) Take the above raw materials in proportion, crush them and set them aside; (2) Put gypsum into a container, add 20 times the amount of purified water, boil over high heat until boiling, then simmer over low heat for 0.5 hours, filter, and obtain gypsum decoction; (3) Soak raw vine, forsythia, platycodon, angelica, anemarrhena, aster, stemona, burdock, roasted turtle shell, apricot kernel, gypsum decoction, ephedra, licorice, ophiopogon, scutellaria, and bupleurum in 20 times the amount of purified water for 30 minutes, add gypsum decoction, boil over high heat until boiling, then simmer over low heat for 30 minutes, add honeysuckle, chrysanthemum, mint, and artemisia annua and decoct together for 10 minutes, filter, and collect the filtrate; (4) Take the filter residue and add 10 times the amount of purified water, boil over high heat until boiling, then simmer over low heat for 10 minutes, filter, combine the two filtrates, concentrate the filtrate, and obtain the extract.

[0037] The third objective of this invention is to provide the application of the traditional Chinese medicine composition or the pharmaceutical preparation in the preparation of drugs for treating viral pneumonia.

[0038] Preferably, the pathogenic virus in viral pneumonia includes at least one of influenza virus, adenovirus, respiratory syncytial virus, rhinovirus, Haemophilus parainfluenzae virus, coronavirus, cytomegalovirus, and Epstein-Barr virus.

[0039] This invention does not specifically limit the coronaviruses that cause viral pneumonia. This invention also does not specifically limit the influenza viruses that cause viral pneumonia, including but not limited to influenza virus strain H1N1.

[0040] The traditional Chinese medicine composition described in this invention can be used not only in the preparation of drugs for treating viral pneumonia, but also in the preparation of drugs for treating diseases complicated by microbial infections.

[0041] Beneficial effects of this invention:

[0042] This invention provides a traditional Chinese medicine composition for treating viral pneumonia. It is derived from traditional formulas through modification and combination. Years of clinical practice have proven its safety and efficacy. It provides rapid relief of high fever and cough symptoms caused by viral pneumonia and features multi-target, multi-effect, and multi-pathway treatment. The composition contains multiple broad-spectrum antiviral and antibacterial components, making it less likely for pathogens to develop drug resistance. It exhibits significant anti-inflammatory capabilities, enhances the patient's immunity, and has advantages such as rapid onset of action, few side effects, and low cost. It can effectively treat viral pneumonia, alleviate patient suffering, save lives, and reduces the likelihood of post-infection sequelae. Attached Figure Description

[0043] Figure 1 An optical microscope image of primitive MDCK cells;

[0044] Figure 2An optical microscope image of original MDCK cells after infection with influenza virus H1N1.

[0045] Figure 3 An optical microscope image of original MDCK cells + influenza virus H1N1 + negative control serum;

[0046] Figure 4 An optical microscope image of original MDCK cells + influenza virus H1N1 + positive control serum;

[0047] Figure 5 An optical microscope image of serum composed of primitive MDCK cells, influenza virus H1N1, and traditional Chinese medicine. Detailed Implementation

[0048] The technical solution of the present invention will be described in detail below through specific embodiments. However, it should be clearly stated that these embodiments are for illustrative purposes only and are not intended to limit the scope of the present invention.

[0049] Example 1

[0050] A traditional Chinese medicine composition, by weight, comprises the following ingredients: 6g of raw vine, 15g of honeysuckle, 15g of chrysanthemum, 9g of peppermint, 13g of forsythia, 5g of platycodon, 5g of angelica dahurica, 10g of anemarrhena asphodeloides, 5g of aster, 8g of stemona japonica, 5g of burdock, 15g of processed turtle shell, 5g of artemisia annua, 5g of apricot kernel, 10g of gypsum, 7g of ephedra, 5g of licorice, 5g of ophiopogon japonicus, 10g of scutellaria baicalensis, and 5g of bupleurum chinense.

[0051] A kind of extract preparation method includes: (1) taking the above raw materials and crushing them for later use; (2) putting gypsum into a container, adding 20 times the amount of purified water, boiling over high heat until boiling, then simmering over low heat for 0.5 hours, filtering to obtain gypsum decoction; (3) soaking raw vine, forsythia, platycodon, angelica, anemarrhena, aster, stemona, burdock, roasted turtle shell, apricot kernel, gypsum decoction, ephedra, licorice, ophiopogon, scutellaria, and bupleurum in 20 times the amount of purified water for 30 minutes, adding gypsum decoction, boiling over high heat until boiling, then simmering over low heat for 30 minutes, adding honeysuckle, chrysanthemum, mint, and artemisia annua and decocting together for 10 minutes, filtering and collecting the filtrate; (3) taking the filter residue and adding 10 times the amount of purified water, boiling over high heat until boiling, then simmering over low heat for 10 minutes, filtering and combining the two filtrates, concentrating the filtrate to obtain the extract.

[0052] Example 2

[0053] A type of traditional Chinese medicine granule, by weight, comprises the following ingredients: 150g of raw vine, 150g of honeysuckle, 100g of chrysanthemum, 120g of peppermint, 100g of forsythia, 150g of platycodon, 130g of angelica dahurica, 100g of anemarrhena, 150g of aster, 150g of stemona japonica, 150g of burdock, 300g of processed turtle shell, 200g of artemisia annua, 150g of apricot kernel, 300g of gypsum, 120g of ephedra, 100g of licorice, 150g of ophiopogon japonicus, 150g of scutellaria baicalensis, and 100g of bupleurum chinense.

[0054] The preparation method of the traditional Chinese medicine granules includes:

[0055] (1) Place gypsum in a container, add 20 times the amount of purified water, boil over high heat until boiling, then simmer over low heat for 0.5 hours, filter to obtain gypsum decoction; (2) Soak raw vine, forsythia, platycodon, angelica, anemarrhena, aster, stemona, burdock, prepared turtle shell, apricot kernel, gypsum decoction, ephedra, licorice, ophiopogon, scutellaria, and bupleurum in 20 times the amount of purified water for 30 minutes, add gypsum decoction, and boil over high heat until boiling. Boil and simmer for 30 minutes, add honeysuckle, chrysanthemum, mint and artemisia and simmer for 10 minutes, filter and collect the filtrate; (3) Take the filter residue and add 10 times the amount of purified water, boil over high heat until boiling and simmer over low heat for 10 minutes, filter and combine the two filtrates, concentrate the filtrate to obtain the extract; (4) Add an appropriate amount of cyclodextrin to the obtained extract to prepare soft material, granulate through a 24-mesh sieve, dry at 50℃ to obtain granules.

[0056] Example 3

[0057] A traditional Chinese medicine decoction, by weight, comprises the following ingredients: 15g of raw vine, 15g of honeysuckle, 12g of chrysanthemum, 12g of peppermint, 10g of forsythia, 15g of platycodon, 15g of angelica dahurica, 12g of anemarrhena asphodeloides, 15g of aster, 15g of stemona japonica, 15g of burdock seed, 30g of prepared turtle shell, 20g of artemisia annua, 15g of apricot kernel, 30g of gypsum, 12g of ephedra, 10g of licorice, 15g of ophiopogon japonicus, 15g of scutellaria baicalensis, and 15g of bupleurum chinense.

[0058] The preparation method of the traditional Chinese medicine decoction includes:

[0059] (1) Place gypsum in a container, add 20 times the amount of purified water, boil over high heat until boiling, then simmer over low heat for 0.5 hours, filter to obtain gypsum decoction; (2) Soak raw vine, forsythia, platycodon, angelica, anemarrhena, aster, stemona, burdock, roasted turtle shell, apricot kernel, gypsum decoction, ephedra, licorice, ophiopogon, scutellaria, and bupleurum in 20 times the amount of purified water for 30 minutes, add gypsum decoction, boil over high heat until boiling, then simmer over low heat for 30 minutes, add honeysuckle, chrysanthemum, mint, and artemisia annua and decoct for 10 minutes, filter and collect the filtrate; (3) Take the residue and add 10 times the amount of purified water, boil over high heat until boiling, then simmer over low heat for 10 minutes, filter and combine the two filtrates, which can be used as a decoction. Adults should take it in 4 divided doses per day.

[0060] To study the pharmacological effects of the aforementioned traditional Chinese medicine composition, Lianhua Qingwen capsules (Yiling Pharmaceutical) were used as a positive control drug. The antiviral and anti-inflammatory effects of this traditional Chinese medicine composition were evaluated using the following in vitro and in vivo experimental methods:

[0061] (1) In vitro inhibitory experiment of serum of traditional Chinese medicine composition against influenza virus strain H1N1

[0062] Three male SD rats were administered purified water by gavage as a negative control group; three male SD rats were administered a clinically equivalent dose of Lianhua Qingwen capsule contents suspension by gavage as a positive control group; and three male SD rats were administered a clinically equivalent dose of this traditional Chinese medicine decoction by gavage as an experimental group.

[0063] After three consecutive days of gavage, blood was collected from the heart of anesthetized rats. The blood collection tubes were left to stand at room temperature for 30 minutes, then centrifuged at 1600g for 10 minutes at 4℃ to collect serum. The serum from three rats in each group was mixed to obtain negative control serum, positive control serum, and serum from the traditional Chinese medicine composition.

[0064] Canine kidney cells (MDCK) were seeded into 96-well culture plates and cultured at 37°C with 5% CO2 for 24 hours. After the cells formed a monolayer, influenza virus H1N1 PR8 / 34 subtype culture medium (50×TCID50) was added to infect the cells for 2 hours. After removing the virus solution, the medium was replaced with serum containing a traditional Chinese medicine composition diluted to 15% with RPMI 1640 medium, negative control serum, and positive control serum, respectively. Cytopathic effect (CPE) was observed under a microscope daily. After 72 hours, when the virus control cells were fully infected, the inhibitory effect of the samples on influenza virus-induced cytopathic effect was determined.

[0065] (1) Optical micrograph of primitive MDCK cells observed under a 200x light microscope. Figure 1 As shown; (2) Optical microscope image of the original MDCK cells after 72 hours of infection with influenza virus H1N1 PR8 / 34 subtype culture medium. Figure 2As shown; (3) After removing the virus solution, the optical microscope image after 72 hours of replacing it with negative control serum is shown. Figure 3 As shown; (4) After removing the virus solution, the optical microscope image after 72 hours of replacing it with positive control serum is shown. Figure 4 As shown; (5) After removing the virus solution, the optical microscope image of the serum containing the traditional Chinese medicine composition after 72 hours is shown. Figure 5 As shown.

[0066] It can be seen that both Lianhua Qingwen capsules and the traditional Chinese medicine decoction described in this invention have approximately 25% inhibitory activity against CPE induced by the H1N1 influenza virus strain. This experiment demonstrates that the traditional Chinese medicine decoction described in this invention, like Lianhua Qingwen capsules, possesses direct antiviral capabilities.

[0067] (2) Anti-inflammatory activity test

[0068] Twenty-four healthy male Kunming mice of SFP grade were purchased and acclimatized to the animal facility for one week, weighing 18–22 g. The required environmental temperature was (22±1)℃ and the relative humidity was maintained at (55±5)%. During the feeding period, the mice had free access to water and food, and all conditions were strictly implemented in accordance with the relevant requirements for laboratory animals.

[0069] Mice were randomly divided into four groups: a negative control group, a sepsis model group, a Lianhua Qingwen capsule group, and a traditional Chinese medicine decoction group. The sepsis model group, Lianhua Qingwen capsule group, and traditional Chinese medicine decoction group received intraperitoneal injections of lipopolysaccharide (LPS) solution at a dose of 15 mg / kg, while the negative control group received an equal volume of sterile saline intraperitoneally. Seven hours after modeling, the Lianhua Qingwen capsule group and the traditional Chinese medicine decoction group were administered a clinically equivalent dose via gavage at 0.1 ml / 10 g. The negative control group and the sepsis model group were administered an equal volume of sterile purified water via gavage. Gavage was performed twice daily, once in the morning and once in the afternoon, for three consecutive days. The survival rate and performance of each group were observed and recorded daily via video.

[0070] Observations revealed that: (1) Animals in the negative control group maintained the same mental state as before modeling throughout the experiment. Seven hours after intraperitoneal injection of LPS solution, animals were observed to be lethargic, with dull fur, reduced activity, chills, and loose stools; (2) Twenty-four hours after modeling, the sepsis model group experienced worsening symptoms, becoming weaker, with bristling fur, severely swollen and red eyes that were difficult to open, and discharge from the corners of the eyes. Their condition improved slightly the next day and further improved on the third day. Two mice died within three days; (3) Twenty-four hours after gavage, the Lianhua Qingwen capsule group showed milder inflammatory symptoms than the sepsis model group. Two mice died within three days; (4) The herbal decoction group showed significantly milder inflammatory symptoms at each time point after gavage compared to the Lianhua Qingwen capsule group. Animals were in better mental condition, more active, with smoother fur, normal eyes, and no animal deaths. This experiment demonstrates that the herbal decoction described in this invention has stronger anti-inflammatory capabilities and better therapeutic effects than the Lianhua Qingwen capsule.

[0071] Typical clinical treatment cases

[0072] Case 1: Dai, male, 8 years old, had a fever of 39 degrees Celsius or higher for more than three days, severe cough, shortness of breath, and chest X-ray showed posterior basal lesions in the lower lobe of the right lung. His condition did not improve after the administration of antibiotics and antiviral drugs. After taking the traditional Chinese medicine decoction described in Example 3, his body temperature returned to normal the next day, his cough was significantly relieved, the fine moist rales in the right lung disappeared on the third day, and he recovered after seven days.

[0073] Case 2: Mr. Gong, male, 26 years old, caught a chill after falling into the water, developed a fever of 40 degrees Celsius, headache, muscle aches, and cough with thick, yellow phlegm that was difficult to expectorate. He was diagnosed with influenza complicated by lobar pneumonia and bacterial infection at the hospital. After taking the traditional Chinese medicine decoction described in Example 3, his temperature returned to normal the next day, his cough subsided, and he recovered completely after 5 days.

[0074] Case 3: Ms. Jia, 45 years old, presented with a persistent fever above 39 degrees Celsius for three days, along with sore throat, severe cough, white and sticky sputum, chest tightness, and fatigue. A CT scan revealed multiple patchy ground-glass opacities in the lower lobes of both lungs. A nasal swab test for novel coronavirus antigen was positive, and a nucleic acid test for novel coronavirus was also positive, confirming a diagnosis of novel coronavirus infection. After treatment with the traditional Chinese medicine decoction described in Example 3, her temperature returned to normal the following day, her cough and sore throat subsided, her sputum became thinner and clearer, and her overall condition improved significantly. Seven days later, both the nasal swab test for novel coronavirus antigen and the nucleic acid test were negative.

[0075] Case 4: Mr. Zhang, male, 78 years old, presented with a persistent fever above 38.5 degrees Celsius for four days, cough with thick sputum, chest tightness and chest pain, constipation, and a fingertip oxygen saturation of 90%. A CT scan revealed multiple infectious lesions in both lungs. Both novel coronavirus antigen and nucleic acid tests were positive, confirming a diagnosis of novel coronavirus infection. After two days of treatment with the traditional Chinese medicine decoction described in Example 3, his body temperature returned to normal, his cough subsided, his chest tightness and pain disappeared, his oxygen saturation returned to 95%, and his mental state improved significantly. Six days later, his symptoms completely disappeared, and a CT scan showed normal lungs. Eight days later, both novel coronavirus antigen and nucleic acid tests were negative.

[0076] The above description is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in the present invention, based on the technical solution and inventive concept of the present invention, should be covered within the scope of protection of the present invention.

Claims

1. A traditional Chinese medicine composition for treating viral pneumonia, characterized in that, The medicinal materials, by weight, are: 10-30 parts of raw vine, 10-30 parts of honeysuckle, 10-30 parts of chrysanthemum, 10-30 parts of peppermint, 10-30 parts of forsythia, 10-30 parts of platycodon, 10-30 parts of angelica dahurica, 10-30 parts of anemarrhena asphodeloides, 10-30 parts of stemona japonica, 10-30 parts of burdock, 10-30 parts of processed turtle shell, 10-30 parts of artemisia annua, 10-30 parts of apricot kernel, 10-30 parts of gypsum, 10-30 parts of ephedra, 10-30 parts of licorice, 10-30 parts of ophiopogon japonicus, 10-30 parts of scutellaria baicalensis, and 10-30 parts of bupleurum chinense.

2. A pharmaceutical preparation, characterized in that, The traditional Chinese medicine composition as described in claim 1 is included.

3. The pharmaceutical preparation according to claim 2, characterized in that, It also includes pharmaceutically acceptable excipients.

4. The pharmaceutical preparation according to claim 2, characterized in that, The pharmaceutical preparation is any one of the following: ointment, decoction, tablet, granule, capsule, powder, pill, drop, tea, or mixture.

5. The use of the traditional Chinese medicine composition according to claim 1 or the pharmaceutical preparation according to any one of claims 2-4 in the preparation of a drug for treating viral pneumonia.

6. The application according to claim 5, characterized in that: The pathogenic virus in the viral pneumonia is at least one of the following: influenza virus, adenovirus, respiratory syncytial virus, rhinovirus, Haemophilus parainfluenzae virus, coronavirus, cytomegalovirus, and Epstein-Barr virus.

Images