An automatic cleaning device for a dissolution tester

Abstract

This invention relates to an automatic cleaning device for a dissolution apparatus, comprising a telescopic base and a rotating nozzle. The telescopic base includes several telescopic discs nested sequentially from the outside to the inside. The bottom of each telescopic disc is hollow, and the top of each telescopic disc has an opening for accommodating another telescopic disc. The top of the innermost telescopic disc is equipped with a rotating nozzle connected to the opening. A sealing ring is provided at the top of the inner wall of all telescopic discs except the innermost one. A sealing ring is provided at the bottom outer end of the bottom of all telescopic discs except the outermost one. The side of the sealing ring fits against the inner wall of the adjacent telescopic disc, and the top of the sealing ring cooperates with the sealing ring for sealing. By injecting water into the inner cavity of the telescopic base, the telescopic discs rise sequentially from the inside to the outside under water pressure and are rotated and sprayed by the rotating nozzle, which can greatly improve cleaning efficiency, effectively remove drug residues in the dissolution cup, and ensure the cleaning quality of the dissolution cup.

Description

Technical Field

[0001] This invention belongs to the field of drug dissolution apparatus technology, specifically relating to an automatic cleaning device for a dissolution apparatus. Background Technology

[0002] Tablet dissolution testing begins with culture medium preparation. The test medium is prepared at a specific pH and temperature, degassed at 6 PPM, and then precisely transferred to the dissolution vessel. During the test, the culture medium temperature is maintained at 37 degrees Celsius to ensure the tablets dissolve at body temperature. After the test, all test media must be collected, and all dissolution vessels must be cleaned for the next test. Currently, cleaning the dissolution vessels requires manual removal, rinsing, and air-drying. During manual cleaning, the vessel opening is upwards, and sediment may remain at the bottom, necessitating multiple, prolonged rinsing sessions.

[0003] Chinese patent document CN202223338523.6 discloses a drug dissolution apparatus. This application includes a cleaning device comprising a cleaning tank fixedly connected to a base. The cleaning tank has a water supply pipe inside, and two water spray pipes are fixedly connected to the inner bottom wall of the cleaning tank, communicating with the water supply pipe. Each water spray pipe has multiple spray nozzles. A baffle is fixedly connected inside the cleaning tank. Both ends of the water supply pipe extend out of the cleaning tank and connect to two branch pipes for cleaning the dissolution cups. This application cleans the dissolution cups by inverting them and placing them inside the cleaning tank, then rinsing them with water spray pipes. While this effectively removes residual drug from the dissolution cups, the cleaning device has a fixed structure, occupies a large space, and has a low degree of automation. Summary of the Invention

[0004] To address the aforementioned problems, this invention discloses an automatic cleaning device for dissolution apparatus, which solves the problem that existing dissolution apparatus cleaning devices cannot thoroughly remove drug residues when cleaning the dissolution cup. Furthermore, the cleaning device can automatically rise to the dissolution cup under water pressure for efficient rinsing.

[0005] The specific technical solution is as follows:

[0006] An automatic cleaning device for a dissolution apparatus includes a telescopic base and a rotating nozzle. The telescopic base comprises a plurality of telescopic discs nested sequentially from the outside to the inside. The bottom ends of each telescopic disc are hollow, and the top of each disc has an opening for accommodating another telescopic disc. The innermost telescopic disc has a rotating nozzle connected to the opening at its top. All telescopic discs except the innermost one have a sealing ring at the top of their inner walls. All other telescopic discs except the outermost one have a sealing ring at their top. Each telescopic disc has a sealing ring on its outer bottom edge. The side of the sealing ring fits against the inner wall of the adjacent telescopic disc, and the top of the sealing ring cooperates with the sealing ring to seal. The outermost telescopic disc has a sealing plate at its bottom edge, which forms a closed space inside the telescopic base. A water inlet pipe runs through the sealing plate and is connected to the inner cavity of the telescopic base. Water is injected into the inner cavity of the telescopic base through the water inlet pipe, causing the telescopic discs to rise one by one from the inside to the outside under the action of water pressure and to rotate and spray the inside of the dissolution cup through the rotating nozzle.

[0007] Furthermore, except for the innermost telescopic disc, all telescopic discs have a limiting ring on their inner sidewall for supporting and positioning the sealing ring. The sealing ring has a stepped groove on its side that is adapted to the size of the limiting ring.

[0008] Furthermore, the upper end of the innermost telescopic disc is provided with a threaded seat that communicates with the through-hole, and the rotating nozzle is screwed onto the threaded seat.

[0009] Furthermore, all telescopic discs except the outermost telescopic disc are equipped with pressing parts at their top ends. One end of each pressing part is fixedly connected to the top of one of the telescopic discs, and the other end of each pressing part is attached to the top of another adjacent telescopic disc.

[0010] Furthermore, all the pressing components are ring-shaped, and the pressing components are sequentially connected from the inside to the outside.

[0011] Furthermore, the top of the telescopic base is provided with a mounting groove for accommodating the pressing component, and when the telescopic base is retracted, the top of the telescopic base is horizontal.

[0012] Furthermore, the bottom of the outermost telescopic disc is provided with a horizontal annular support plate, the bottom of which is fixedly connected to the sealing plate, and the upper end of which is fitted to the bottom of the other telescopic discs.

[0013] Furthermore, the inner diameter of each of the openings corresponds to the diameter of its adjacent telescopic disc.

[0014] The beneficial effects of this invention are reflected in:

[0015] (1) The present invention uses a telescopic base in conjunction with a rotating nozzle. Under the action of water pressure, the rotating nozzle can be raised into the inverted dissolution cup by the telescopic base and rotated for rinsing. This can greatly improve the cleaning efficiency, effectively remove drug residues in the dissolution cup, and ensure the cleaning quality of the dissolution cup.

[0016] (2) The present invention has a compact structure. The telescopic base is composed of several closely fitting telescopic discs. By injecting water into the inner cavity of the telescopic base, the telescopic discs automatically extend upward under the action of water pressure. The telescopic discs are sealed by sealing rings and sealing rings pressing against each other to prevent leakage and ensure the rinsing quality of the rotating nozzle. Furthermore, a pressing component is set on the top of the telescopic discs so that the telescopic base can automatically descend and retract after rinsing, reducing space occupation. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the structure during the contraction process of the present invention.

[0018] Figure 2 This is a side view of the invention when it is contracted.

[0019] Figure 3 for Figure 2 Sectional view along line AA.

[0020] Figure 4 This is a top view of the present invention.

[0021] Figure 5 This is a schematic diagram of the structure of the present invention when it is extended.

[0022] Figure 6 This is a side sectional view of the invention when it is extended.

[0023] 1. Telescopic base; 2. Telescopic disc; 21. Through port; 22. Threaded seat; 23. Annular support plate; 24. Sealing ring; 25. Sealing ring; 25. Step groove; 26. Limiting ring; 27. Mounting groove; 28. Pressing component; 3. Sealing plate; 4. Water inlet pipe; 5. Rotating nozzle. Detailed Implementation

[0024] To make the technical solution of this invention clearer and more explicit, the invention will be further described below with reference to the accompanying drawings. Any solution derived by equivalent substitution and conventional reasoning of the technical features of this invention falls within the protection scope of this invention. The fixed connections and fixed installations mentioned in this invention are all common connection methods in the mechanical field, including welding, bolt and nut connections, and screw connections.

[0025] In the description of this invention, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0026] Please see Figure 1-6 This embodiment provides an automatic cleaning device for a dissolution apparatus, including a telescopic base 1 and a rotating nozzle 5. The telescopic base 1 includes several telescopic discs 2 nested sequentially from the outside to the inside. The bottom end of each telescopic disc 2 is hollow, and the top center of each telescopic disc 2 has an opening 21 for accommodating another telescopic disc 2. The inner diameter of each opening 21 corresponds to the diameter of its adjacent telescopic disc 2. The top center of the innermost telescopic disc 2 has a threaded seat 22 that communicates with the opening 21, and the rotating nozzle 5 is screwed onto the threaded seat 22. The bottom of the outermost telescopic disc 2 has a horizontally arranged annular support plate 23. The upper end of the annular support plate 23 is fitted against the bottom of the other telescopic discs 2 and serves as a support and positioning element.

[0027] All telescopic discs 2 except the innermost telescopic disc 2 have a sealing ring 24 at the top of their inner walls. All telescopic discs 2 except the outermost telescopic disc 2 have a sealing ring 25 at their bottom outer ends. The sides of the sealing ring 25 are fitted against the inner walls of the adjacent telescopic discs 2, and the top of the sealing ring 25 cooperates with the sealing ring 24 to seal. A sealing plate 3 is fixedly connected to the bottom of the annular support plate 23. The sealing plate 3 seals the bottom of the telescopic base 1, forming a closed space inside the telescopic base 1. A water inlet pipe 4, which is connected to the inner cavity of the telescopic base 1, runs through the center of the sealing plate 3. Water is injected into the inner cavity of the telescopic base 1 through the water inlet pipe 4, causing the telescopic discs 2 to rise one by one from the inside out under water pressure. This allows the rotating nozzle 5 to extend upward into the inverted dissolution cup. The rotating nozzle 5 can automatically rotate and spray under water pressure, thereby rinsing the inside of the dissolution cup. The inverted cleaning of the dissolution cup allows drug residues to be discharged quickly, improving cleaning efficiency.

[0028] In this embodiment, except for the innermost telescopic disc 2, all telescopic discs 2 are provided with limiting rings 26 on their inner sidewalls for supporting and positioning the sealing ring 24. The upper side of the sealing ring 25 is provided with a stepped groove 251 that is adapted to the size of the limiting ring 26, so that when the telescopic base 1 extends upward, the stepped groove 251 of the sealing ring 25 can accommodate the limiting ring 26, so that the top of the sealing ring 25 can fit tightly with the bottom of the sealing ring 24 to achieve a seal.

[0029] In this embodiment, to prevent excessive friction between the telescopic discs 2 after rinsing, which could cause the telescopic base 1 to fail to retract automatically and uniformly, annular pressing members 28 are provided at the top of all telescopic discs 2 except the outermost one. The weight of the pressing members is selected according to the actual situation. One inner end of each pressing member 28 is fixedly connected to the top of one of the telescopic discs 2, and one outer end of each pressing member 28 is attached to the top of another adjacent telescopic disc 2. This allows the inner telescopic disc 2 to press down on the outer telescopic disc 2 after it descends, thereby driving the outer telescopic disc 2 to descend as the inner telescopic disc 2 descends, thus enabling the telescopic base 1 to retract automatically and uniformly.

[0030] In this embodiment, the top of the telescopic base 1 is provided with a mounting groove 27 for accommodating the pressing member 28, and the pressing members 28 are sequentially connected from the inside to the outside. When the telescopic base 1 is retracted, the top of the telescopic base 1 is horizontal.

[0031] The rotating nozzle used in this embodiment is a conventional rotating cleaning nozzle, such as the K4-19250 tank cleaning nozzle produced by Hunan Changyuan Company, which will not be described in detail here.

[0032] The above description is merely a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the scope of the technology disclosed in the present invention should be included within the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be determined by the scope of the claims.

Claims

1. An automatic cleaning device for a dissolution apparatus, characterized in that, The device includes a telescopic base (1) and a rotating nozzle (5). The telescopic base (1) includes several telescopic discs (2) that are sequentially nested from the outside to the inside. The bottom of each telescopic disc (2) is hollow, and the top of each telescopic disc (2) has an opening (21) for accommodating another telescopic disc (2). The top of the innermost telescopic disc (2) is provided with a rotating nozzle (5) that communicates with the opening (21). The top of the inner wall of all telescopic discs (2) except the innermost telescopic disc (2) is provided with a sealing ring (24). The bottom of all telescopic discs (2) except the outermost telescopic disc (2) is sealed. A sealing ring (25) is provided at the bottom of the outer side of each end. The side of the sealing ring (25) is fitted with the inner wall of the adjacent telescopic disc (2). The top of the sealing ring (25) is sealed with the sealing ring (24). The bottom of the telescopic disc (2) located on the outermost side is provided with a sealing plate (3), which makes the inner cavity of the telescopic base (1) form a closed space. A water inlet pipe (4) connected to the inner cavity of the telescopic base (1) is provided through the sealing plate (3). Water is injected into the inner cavity of the telescopic base (1) through the water inlet pipe (4), so that the telescopic disc (2) rises from the inside to the outside under the action of water pressure and is sprayed into the inside of the dissolution cup by the rotating nozzle (5). All telescopic discs (2) except the outermost telescopic disc (2) are provided with pressing members (28) at their top ends. One end of each pressing member (28) is fixedly connected to the top of one of the telescopic discs (2), and the other end of each pressing member (28) is attached to the top of another adjacent telescopic disc (2). The pressing members (28) are all in a ring shape, and the pressing members (28) are connected from the inside to the outside in sequence. The top of the telescopic base (1) is provided with a mounting groove (27) for accommodating the pressing members (28), and when the telescopic base (1) is retracted, the top of the telescopic base (1) is horizontal. Except for the innermost telescopic disc (2), all telescopic discs (2) have a limiting ring (26) on their inner sidewalls for supporting and positioning the sealing ring (24). The sealing ring (25) has a stepped groove (251) on its side that is adapted to the size of the limiting ring (26). The innermost telescopic disc (2) has a threaded seat (22) connected to the through port (21) at its upper end, and the rotating nozzle (5) is screwed onto the threaded seat (22).

2. The automatic cleaning device for a dissolution apparatus as described in claim 1, characterized in that, The bottom of the outermost telescopic disc (2) is provided with a horizontal annular support plate (23). The bottom of the annular support plate (23) is fixedly connected to the sealing plate (3), and the upper end of the annular support plate (23) is fitted to the bottom of the other telescopic discs (2).

3. The automatic cleaning device for a dissolution apparatus as described in claim 1, characterized in that, The inner diameter of each of the openings (21) corresponds to the diameter of its adjacent telescopic disc (2).

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