A constant temperature perfusion system with adjustable neurointerventional perfusion pressure and its use method

The constant temperature perfusion system addresses infusion inaccuracies by using electromagnetic and elastic components to adjust squeezing forces, improving accuracy and rebound efficiency in neurointerventional drug delivery.

CN118142019BActive Publication Date: 2025-01-03THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV +1
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Patent Information

Application Number
CN202410252038.1
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-03-06
Publication Date
2025-01-03
Estimated Expiration
2044-03-06

AI Technical Summary

Technical Problem

Existing neurointerventional infusion systems face issues with infusion tube bending and elastic creep, leading to inaccuracies in drug delivery due to the extrusion of the infusion tube during operation, which affects the infusion accuracy and rebound efficiency.

Method used

A constant temperature perfusion system with adjustable neurointerventional perfusion pressure, utilizing electromagnetic and elastic components to detect and correct tube twisting and creeping, ensuring accurate and efficient drug delivery through a peristaltic structure with adjustable squeezing forces.

Benefits of technology

Improves infusion accuracy by correcting tube twisting and enhancing rebound efficiency, maintaining precise drug delivery to the catheter, and preventing slow rebound, thus ensuring reliable treatment outcomes.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention relates to the technical field of neurointerventional treatment instruments, and in particular to a constant temperature perfusion system with adjustable neurointerventional perfusion pressure and a method for using the system, comprising a shell, an upper baffle is provided inside the shell, a driving device is provided on the top of the upper baffle, an extrusion assembly is provided below the upper baffle, a lower baffle is provided at the bottom of the extrusion assembly, a bearing platform is provided below the lower baffle, and an infusion tube is provided above the bearing platform; fixed rings are symmetrically provided on the top of the bearing platform, an annular sleeve is provided on the inner ring of the fixed ring, the annular sleeve fixes the infusion tube, a fixing assembly is provided on the outer side of the annular sleeve, a limit rod is provided between the two fixed rings, and an adjustment assembly is provided on the two limit rods; by detecting the compression amount of the elastic member, the specific state of the infusion tube between the connecting plates is obtained, and the electromagnetic member and the fixing assembly are controlled to perform corresponding specific actions according to the state of the infusion tube, thereby solving the problem of distortion and creep of the infusion tube during the movement of the driving motor.
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Description

Technical Field

[0001] The present invention relates to the technical field of neurointerventional therapeutic instruments, and in particular to a constant temperature perfusion system with adjustable neurointerventional perfusion pressure and a method of using the system. Background Art

[0002] In neurosurgery, the use of non-open interventional treatment is gradually becoming popular. Interventional treatment is a general term for a series of technologies that use puncture needles, catheters and other interventional equipment to introduce specific instruments into the body's lesions through natural channels or tiny incisions under the guidance and monitoring of imaging equipment such as digital subtraction angiography, CT, ultrasound and magnetic resonance imaging. Compared with surgical treatment, it is less traumatic, has a shorter recovery period, and has less surgical impact on patients. Therefore, it is widely used in the field of neurosurgery.

[0003] A Chinese patent with application number 202120497664.9 discloses an interventional drug treatment device for oncology, including an interventional device body and a control panel, a groove is provided on the left side of the interventional device body, a medicine tank is installed in the groove, a heating plate is installed on the lower inner wall of the groove, a pressure sensor is installed on the bottom inner wall of the groove, the medicine tank is connected to an infusion pump through a hose, and the infusion pump is connected to an infusion port through a hose, a fluid accumulation tank is provided on the right side of the medicine tank, and the top of the fluid accumulation tank is connected to a liquid extraction pump through a hose, and the pressure sensor and display screen installed at the bottom of the medicine tank can confirm the patient's medicine input amount and the remaining medicine amount in the medicine tank, so as to facilitate confirmation of the treatment plan according to the patient's actual situation.

[0004] Although the above patent can detect the amount of liquid medicine input and the remaining amount of liquid medicine in the liquid medicine tank, in the process of delivering liquid medicine through the infusion pump, the extrusion group in the infusion pump sequentially squeezes the infusion tube between the extrusion group and the baffle (extrusion zone) at a set speed to make the liquid in the infusion tube flow forward. The infusion pipeline in the extrusion zone is easy to bend due to the extrusion of the peristaltic device during operation, which increases the length of the infusion tube in the extrusion zone and affects the infusion accuracy.

[0005] At the same time, under the long-term reciprocating extrusion of the extrusion group, the infusion tube located inside the extrusion area is affected by elastic creep, resulting in a delay in the rebound of the infusion tube, affecting the infusion accuracy.

[0006] Therefore, it is necessary to invent a constant temperature perfusion system with adjustable neurointerventional perfusion pressure and a method of using the system to solve the above problems. Summary of the invention

[0007] The object of the present invention is to provide a constant temperature perfusion system with adjustable neurointerventional perfusion pressure and a method of using the same, so as to solve the technical problems raised in the above-mentioned background technology.

[0008] To achieve the above object, the present invention provides the following technical solutions:

[0009] A constant temperature perfusion system with adjustable neurointerventional perfusion pressure comprises a shell, an upper partition is provided inside the shell, a driving device is provided on the top of the upper partition, an extrusion assembly is provided below the upper partition, a lower partition is provided at the bottom of the extrusion assembly, the extrusion assembly is movably connected to the lower partition, a bearing platform is provided below the lower partition, and an infusion tube is provided above the bearing platform.

[0010] A fixing ring is symmetrically provided on the top of the supporting platform, an electric heating device is provided inside the fixing ring, an annular sleeve is provided on the inner ring of the fixing ring, the annular sleeve fixes the infusion tube, a fixing component is provided on the outer side of the annular sleeve, and the fixing component is used for adjusting the squeezing force of the fixing ring on the infusion tube.

[0011] A limit rod is provided between the two fixing rings, and an adjustment assembly is provided on the two limit rods. The adjustment assembly includes connecting blocks arranged in an array on the outside of the limit rods, and elastic members are provided on the outside of the connecting blocks. A connecting plate is provided at one end of the elastic member away from the connecting block, and the connecting plate is located in the area between the two limit rods. The opposite sides of the two corresponding connecting plates are in contact with the outside of the infusion tube, and an electromagnetic member is provided at the connection between the connecting plate and the elastic member.

[0012] The present invention arranges electromagnetic components and elastic components, and obtains the specific state of the connecting plate, that is, the state of the infusion tube between the two connecting plates by detecting the compression amount of the elastic components. Then, according to the specific state of the infusion tube, the electromagnetic components are controlled to perform corresponding actions. When the infusion tube is twisted, the electromagnetic block forces the elastic component with excessive compression to displace relative to the connecting plate. During the displacement of the connecting plate, on the one hand, the infusion tube is squeezed to improve the infusion accuracy of the infusion tube; on the other hand, the twisted part that affects the infusion accuracy is corrected, so that the infusion tube returns to the bottom of the pressing block. When the infusion tube creeps, the electromagnetic block is continuously switched on and off, forcing the connecting plates on both sides of the infusion tube to squeeze the infusion tube, thereby improving the rebound efficiency of the infusion tube and avoiding the delivery of the medicine due to the slow rebound of the infusion tube.

[0013] Furthermore, the electromagnetic component includes an electromagnetic block arranged on the connecting plate, and a magnetic block corresponding to the electromagnetic block is arranged inside the connecting block. After the electromagnetic block is started, it drives the elastic component to perform telescopic movement.

[0014] Furthermore, the fixing assembly includes a pushing member arranged inside the limiting rod, the telescopic end of the pushing member is provided with an extrusion plate, the end of the extrusion plate is provided with an air storage member, the outside of the air storage member is provided with a delivery pipe, the other end of the delivery pipe is connected to a limiting ring sleeve, and the limiting ring sleeve is located on both sides of the annular sleeve.

[0015] Furthermore, the extrusion assembly includes eccentric wheels distributed in an array, a peristaltic structure is provided at the bottom of the eccentric wheel, a transmission shaft is provided on the outer side of the eccentric wheel, and the transmission shaft is passed through the eccentric wheel.

[0016] The peristaltic structure is slidably connected to the lower partition plate and squeezes the outer wall of the infusion tube; the transmission shaft is used to drive the eccentric wheel to rotate so as to drive the peristaltic structure to reciprocate up and down.

[0017] Furthermore, the peristaltic structure includes a pressure rod slidably connected to the lower partition, the pressure rod is located at the bottom of the eccentric wheel, and the bottom of the pressure rod passes through one end of the lower partition and is connected to a pressure block, and a spring is provided between the pressure block and the lower partition.

[0018] Furthermore, the outer sides of each pressing block are in contact with each other, and during the rotation of the transmission shaft, the eccentric wheel drives the pressing block to perform cosine motion through the pressure rod, and the pressing block presses the outer wall of the infusion tube.

[0019] Furthermore, the driving device includes a driving motor arranged on the top of the upper partition, the output shaft of the driving motor is provided with a transmission wheel, the outer side of the transmission wheel is provided with a transmission belt, the other end of the transmission belt passes through the upper partition and is connected to a connecting wheel arranged at the end of the transmission shaft, and an empty groove for the transmission belt to move is opened on the upper partition.

[0020] Furthermore, a bottle stopper puncture device is installed at one end of the infusion tube, and a needle tube is installed at the other end of the infusion tube. The end of the needle tube is connected to a joint, and the end of the joint is provided with an interconnection device, and the end of the interconnection device is connected to a catheter.

[0021] Furthermore, a human-machine interaction device is provided on the top of the upper partition, and a control system is provided inside the human-machine interaction device, and the control system is used to control the movement of electrical components inside the shell.

[0022] A snap-fit ​​frame is provided at the bottom of the shell, the bottom of the snap-fit ​​frame is flush with the top of the supporting platform, and through grooves are provided at the connection between the two ends of the snap-fit ​​frame and the shell.

[0023] The present invention also provides a method for using the constant temperature perfusion system, which comprises the following steps:

[0024] Step 1: First, pass the infusion tube through the two fixing rings on the carrier, and then connect the two ends of the infusion tube to the external medicine bottle and the connector on the interconnection device, so as to complete the assembly of the infusion tube and the catheter;

[0025] Step 2: After the infusion tube and the catheter are assembled, the amount of liquid medicine that enters the human body per unit time is calculated according to the patient's weight, and the speed of the drive motor is set on the human-machine interaction device according to the calculated value;

[0026] Step 3: Start the drive motor, the drive motor drives the connecting wheel to rotate synchronously through the transmission belt, the connecting wheel drives the peristaltic structure to operate through the eccentric wheel, the peristaltic structure squeezes the infusion tube, so that the liquid medicine in the infusion tube can accurately enter the inside of the catheter;

[0027] Step 4: When the peristaltic structure squeezes the infusion tube, the specific state of the connecting plate, that is, the specific state of the infusion tube between the connecting plates, is obtained by detecting the compression amount of the elastic member. The electromagnetic member and the fixed component are controlled to perform corresponding specific actions according to the state of the infusion tube.

[0028] Technical effects and advantages of the present invention:

[0029] 1. The present invention arranges an electromagnetic component and an elastic component, and obtains the specific state of the infusion tube between the two connecting plates by detecting the compression amount of the elastic component, and controls the electromagnetic component to perform corresponding actions. When the infusion tube is twisted, the electromagnetic block forces the elastic component with excessive compression to displace relative to the connecting plate. During the displacement of the connecting plate, on the one hand, the infusion tube is squeezed to improve the infusion accuracy of the infusion tube; on the other hand, the twisted part that affects the infusion accuracy is corrected, so that the infusion tube returns to the bottom of the pressure block.

[0030] 2. The present invention arranges electromagnetic components and elastic components, detects the compression amount of the elastic components, obtains the specific state of the infusion tube between the connecting plates, and controls the electromagnetic components to perform corresponding actions. When the infusion tube creeps, the electromagnetic block is continuously switched on and off, forcing the connecting plates on both sides of the infusion tube to squeeze the infusion tube, thereby improving the rebound efficiency of the infusion tube and avoiding the impact of slow rebound of the infusion tube on the delivery of the medicine. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 It is a schematic diagram of the main structure of the present invention.

[0032] Figure 2 It is a schematic structural diagram of the housing of the present invention.

[0033] Figure 3 It is a schematic diagram of the internal structure of the housing of the present invention.

[0034] Figure 4 It is a schematic structural diagram of the extrusion assembly of the present invention.

[0035] Figure 5 It is a schematic diagram of the structure of the regulating component and the infusion tube of the present invention.

[0036] Figure 6 It is a schematic diagram of the structure of the regulating component of the present invention.

[0037] Figure 7 It is a schematic structural diagram of the fixing assembly of the present invention.

[0038] Figure 8 This is a schematic diagram of the state of the infusion tube of the present invention when in use.

[0039] Fig. 9 It is a schematic structural diagram of the fixing assembly of the present invention.

[0040] Fig.10 It is a schematic diagram of the structure of the electromagnetic component of the present invention.

[0041] In the figure: 1, housing; 2, driving device; 201, driving motor; 202, transmission wheel; 203, transmission belt; 204, connecting wheel; 205, empty slot; 3, extrusion assembly; 301, eccentric wheel; 302, creeping structure; 3021, pressure rod; 3022, pressure block; 3023, spring; 303, transmission shaft; 4, bearing platform; 5, fixing ring; 6, annular sleeve; 7, fixing assembly; 701, pushing member; 702, extrusion plate; 703, gas storage member; 704, delivery tube; 705, limiting ring; 8, limiting rod; 9, adjustment assembly; 901, connection block; 902, elastic member; 903, connection plate; 904, electromagnetic member; 9041, electromagnetic block; 9042, magnetic block; 10, infusion tube; 11, upper partition; 12, lower partition; 13, electric heating device; 14, bottle stopper piercer; 15, connector; 16, interconnection device; 17, catheter; 18, human-machine interaction device; 19, snap-fit ​​frame; 20, through groove. DETAILED DESCRIPTION

[0042] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0043] Reference Figures 1 to 10As shown, a constant temperature perfusion system with adjustable neurointerventional perfusion pressure includes a shell 1, an upper partition 11 is provided inside the shell 1, a driving device 2 is provided on the top of the upper partition 11, an extrusion assembly 3 is provided below the upper partition 11, a lower partition 12 is provided at the bottom of the extrusion assembly 3, the extrusion assembly 3 is movably connected to the lower partition 12, a supporting platform 4 is provided below the lower partition 12, and an infusion tube 10 is provided above the supporting platform 4.

[0044] A fixing ring 5 is symmetrically provided on the top of the supporting platform 4, and an electric heating device 13 is provided inside the fixing ring 5. After the fixing ring 5 completes the installation of the infusion tube 10, the electric heating device 13 is started to heat the medicine in the infusion tube 10 to ensure that the temperature of the medicine output by the infusion tube 10 is stable and reduce the cold stimulation of the medicine to the blood vessels.

[0045] The inner circle of the fixing ring 5 is provided with an annular sleeve 6 for fixing the infusion tube 10 . The outer side of the annular sleeve 6 is provided with a fixing component 7 for adjusting the squeezing force of the fixing ring 5 on the infusion tube 10 .

[0046] A limiting rod 8 is provided between the two fixing rings 5, and an adjusting assembly 9 is provided on the two limiting rods 8. The adjusting assembly 9 includes a connecting block 901 arranged in an array on the outside of the limiting rod 8, and an elastic member 902 is provided on the outside of the connecting block 901. A connecting plate 903 is provided on the end of the elastic member 902 away from the connecting block 901. The connecting plate 903 is located in the area between the two limiting rods 8, and the opposite sides of the two corresponding connecting plates 903 are in contact with the outside of the infusion tube 10. An electromagnetic member 904 is provided at the connection between the connecting plate 903 and the elastic member 902.

[0047] Specifically, the electromagnetic member 904 includes an electromagnetic block 9041 disposed on the connecting plate 903. A magnetic block 9042 corresponding to the electromagnetic block 9041 is disposed inside the connecting block 901. After being started, the electromagnetic block 9041 drives the elastic member 902 to perform telescopic movement.

[0048] Specifically, the fixing assembly 7 includes a pushing member 701 arranged inside the limiting rod 8, the telescopic end of the pushing member 701 is provided with an extrusion plate 702, the end of the extrusion plate 702 is provided with an air storage member 703, the outer side of the air storage member 703 is provided with a delivery pipe 704, the other end of the delivery pipe 704 is connected to a limiting ring sleeve 705, and the limiting ring sleeve 705 is located on both sides of the annular sleeve 6.

[0049] Specifically, the extrusion assembly 3 includes eccentric wheels 301 distributed in an array, a peristaltic structure 302 is provided at the bottom of the eccentric wheel 301 , a transmission shaft 303 is provided on the outer side of the eccentric wheel 301 , and the transmission shaft 303 is penetrated in the eccentric wheel 301 .

[0050] The peristaltic structure 302 is slidably connected to the lower partition 12 and squeezes the outer wall of the infusion tube 10; the transmission shaft 303 is used to drive the eccentric wheel 301 to rotate so as to drive the peristaltic structure 302 to reciprocate up and down.

[0051] Specifically, the peristaltic structure 302 includes a compression rod 3021 slidably connected to the lower partition 12, the compression rod 3021 is located at the bottom of the eccentric wheel 301, and one end of the bottom of the compression rod 3021 that passes through the lower partition 12 is connected to a pressure block 3022, and a spring 3023 is provided between the pressure block 3022 and the lower partition 12.

[0052] Specifically, the outer sides of the pressing blocks 3022 are in contact with each other. When the transmission shaft 303 rotates, the eccentric wheel 301 drives the pressing blocks 3022 to perform cosine motion through the pressure rod 3021 , and the pressing blocks 3022 squeeze the outer wall of the infusion tube 10 .

[0053] Specifically, the driving device 2 includes a driving motor 201 arranged on the top of the upper partition 11, the output shaft of the driving motor 201 is provided with a transmission wheel 202, the outer side of the transmission wheel 202 is provided with a transmission belt 203, the other end of the transmission belt 203 passes through the upper partition 11 and is connected to a connecting wheel 204 arranged at the end of the transmission shaft 303, and an empty groove 205 is opened on the upper partition 11 for the transmission belt 203 to move.

[0054] Specifically, a bottle stopper puncture device 14 is installed at one end of the infusion tube 10, and a needle tube is installed at the other end of the infusion tube 10. The end of the needle tube is connected to a connector 15, and the end of the connector 15 is provided with an interconnection device 16. The end of the interconnection device 16 is connected to a catheter 17.

[0055] Specifically, a human-machine interaction device 18 is provided on the top of the upper partition 11 , and a control system is provided inside the human-machine interaction device 18 . The control system is used to control the movement of electrical components inside the housing 1 .

[0056] A snap-fit ​​frame 19 is provided at the bottom of the shell 1, and the bottom of the snap-fit ​​frame 19 is flush with the top of the supporting platform 4. Through grooves 20 are provided at the connection between the two ends of the snap-fit ​​frame 19 and the shell 1. When the infusion tube 10 is connected to the fixing ring 5, the snap-fit ​​frame 19 is removed from the shell 1 to provide space for the installation of the infusion tube 10. After the installation is completed, the infusion tube 10 can be snapped onto the shell 1 again. At this time, the infusion tube 10 is located inside the through groove 20.

[0057] The treatment method of neurointerventional perfusion surgery is: puncture the patient's thigh, then insert catheter 17 at the puncture site, catheter 17 follows the blood vessels to the liver, and then sends catheter 17 directly along the blood vessels of the liver into the blood vessels that provide nutrition to the tumor, and then injects therapeutic liquid through catheter 17. The liquid medicine enters the interior of the tumor along the blood vessels, and the liquid medicine destroys the tumor, resulting in the shrinkage of the tumor, so that it can be removed.

[0058] The device is mainly aimed at the technical problem that the accuracy of the drug solution delivered by the infusion tube 10 to the catheter 17 cannot be accurately controlled during neurointerventional perfusion therapy.

[0059] The specific operation steps are as follows: When in use, first pass the infusion tube 10 through the two fixing rings 5 ​​on the supporting platform 4 (specifically as Figure 5 As shown), then the end of the infusion tube 10 with the bottle stopper puncture device 14 is connected to the medicine bottle, and the medicine in the medicine bottle flows out of the medicine bottle along the infusion tube 10 until the medicine flows out of the needle tube, and then the end of the infusion tube 10 with the needle tube is connected to the connector 15 on the interconnection device 16, so that the assembly of the infusion tube 10 and the catheter 17 is completed (as shown in detail). Figure 1 As shown), (the assembly of the infusion tube 10 and the catheter 17 belongs to the prior art and will not be described in detail here).

[0060] Then, the speed of the driving motor 201 is set on the human-machine interaction device 18, so as to control the amount of liquid medicine delivered by the infusion tube 10 to the catheter 17 per unit time. After the speed setting of the driving motor 201 is completed, the driving motor 201 is started to operate, and the output shaft of the driving motor 201 drives the transmission wheel 202 to operate, and the transmission wheel 202 drives the connecting wheel 204 to rotate synchronously through the transmission belt 203. Since both ends of the transmission shaft 303 are rotatably connected to the inner wall of the shell 1, during the rotation of the connecting wheel 204, the transmission wheel 202 synchronously drives the transmission shaft 303 to rotate, and the transmission wheel 202 drives the eccentric wheel 301 to rotate synchronously. Since the bottom of the eccentric wheel 301 is distributed in a cosine curve (specifically as shown in FIG. Figure 8 As shown in the figure, when the transmission shaft 303 rotates, the eccentric wheel 301 is synchronously driven to perform cosine motion. During the operation of the eccentric wheel 301, the outer side of the eccentric wheel 301 squeezes the end of the pressure rod 3021. After the pressure rod 3021 is squeezed, the pressing block 3022 is driven to squeeze the infusion tube 10. The movement state of the pressing block 3022 is a cosine wave state, so that the liquid medicine in the infusion tube 10 can accurately enter the interior of the catheter 17.

[0061] During the process of the pressing block 3022 squeezing the infusion tube 10, the connecting plates 903 on both sides of the infusion tube 10 limit it. After the driving motor 201 is started, the pressing block 3022 squeezes the infusion tube 10, and the cross-section of the infusion tube 10 continuously switches between a circle and an ellipse. During this period, the outer wall of the infusion tube 10 squeezes the connecting plate 903, and the connecting plate 903 squeezes the elastic member 902, so that the elastic member 902 is compressed. A pressure sensor is provided at the connection between the elastic member 902 and the connecting block 901. The human-computer interaction device 18 can obtain the compression amount of the elastic member 902 by detecting the value of the pressure sensor, and obtain the specific state of the connecting plate 903 through the compression amount of the elastic member 902, that is, the state of the infusion tube 10 between the connecting plates 903. Then, according to the specific state of the infusion tube 10, the electromagnetic member 904 and the fixing component 7 are controlled to perform corresponding specific actions.

[0062] It should be noted that the elastic member 902 includes a fixed spring or an elastic telescopic rod, one end of the fixed spring is connected to the connecting plate 903 , and the other end of the fixed spring is connected to the connecting block 901 .

[0063] by Figure 5 For example, the elastic members 902 on the connecting plate 903 are distributed on the left and right sides of the supporting platform 4. When the control system detects that the compression amount of the elastic member 902 on the left side of the supporting platform 4 is greater than the set value, and the compression amount of the elastic member 902 on the right side of the supporting platform 4 is less than the set value, it indicates that when the peristaltic structure 302 squeezes the infusion tube 10, the infusion tube 10 is twisted, thereby causing the movement amount of the connecting plate 903 on the left side of the supporting platform 4 to be greater than the movement amount of the connecting plate 903 on the right side of the supporting platform 4. At this time, the control system passes a positive current into the electromagnetic block 9041 located on the left side of the supporting platform 4 according to the difference in the compression amount of the elastic members 902 on the left and right sides. The electromagnetic block 9041 generates a repulsive force with the magnetic block 9042, forcing the connecting plate 903 on the left side to move to the right. During the displacement of the connecting plate 903 on the left side, on the one hand, the infusion tube 10 is squeezed to improve the infusion accuracy of the infusion tube 10; on the other hand, the twisted part that affects the infusion accuracy is corrected, so that the infusion tube 10 returns to the bottom of the pressing block 3022.

[0064] At the same time, the human-computer interaction device 18 controls the pusher 701 to extend, and the pusher 701 pushes the extrusion plate 702 to squeeze the gas storage member 703. After the gas storage member 703 is squeezed, the internal gas enters the limiting ring sleeve 705 through the delivery pipe 704, and the limiting ring sleeve 705 expands and fixes the infusion tube 10, so that the original single-point limiting and fixing method of the annular sleeve 6 for the infusion tube 10 is transformed into multi-point fixing, which improves the stability of the infusion tube 10 and prevents the infusion tube 10 from twisting again.

[0065] It should be noted that: the limit rod 8 in this embodiment adopts a hollow design, and the pushing member 701 includes an electric push rod, one end of the electric push rod is fixedly connected to the inner wall of the limit rod 8, and the other end of the electric push rod is connected to the extrusion plate 702.

[0066] by Figure 5 For example, when the control system detects that the fluctuation value of the elastic member 902 at a certain position on the left and right sides of the carrier 4 is less than the set state, but the maximum compression amount of the elastic member 902 does not exceed the set value, it indicates that the infusion tube 10 located between the two fixing rings 5 ​​creeps during the long-term squeezing process of the creeping structure 302, that is, the rebound of the infusion tube 10 slows down, resulting in the fluctuation value of the elastic member 902 on the left and right sides of the carrier 4 being less than the set state. At this time, the control system adjusts the electromagnetic blocks 9041 on the left and right sides of the carrier 4 according to the fluctuation value of the elastic members 902 on the left and right sides. A forward current is passed through the part and is continuously switched on and off. The specific action steps are: when the pressing block 3022 moves up, a forward current is passed through, forcing the connecting plates 903 on the left and right sides to move toward the middle of the supporting platform 4, and the connecting plates 903 squeeze the infusion tube 10 to improve the rebound efficiency of the infusion tube 10 and avoid affecting the delivery of the medicine due to the slow rebound of the infusion tube 10; after the pressing block 3022 moves up to the top, the electromagnetic block 9041 is powered off, and the outer wall of the connecting plate 903 only keeps in contact with the outer wall of the infusion tube 10, and the connecting plate 903 does not squeeze the infusion tube 10.

[0067] It should be noted that after the pressing block 3022 moves up to the top, the bottom of the pressing block 3022 remains in contact with the outer wall of the infusion tube 10 .

[0068] by Figure 5 For example, when the control system detects that the fluctuation value of the elastic member 902 at a certain point on the left and right sides of the support platform 4 is less than the set state, but the maximum compression amount of the elastic member 902 is not less than the set value, it indicates that the viscosity of the drug liquid in the infusion tube 10 is relatively high. After being squeezed by the peristaltic structure 302, the infusion tube 10 cannot be completely squeezed, resulting in the fluctuation value of the elastic member 902 on the left and right sides of the support platform 4 being less than the set state. At this time, the control system passes a positive current into the electromagnetic blocks 9041 on the left and right sides of the support platform 4 according to the fluctuation value of the elastic members 902 on the left and right sides and continuously switches on and off, forcing the connecting plates 903 located at the upper and lower ends of the support platform 4 to perform staggered squeezing on the infusion tube 10, thereby improving the transportation effect of the drug liquid with higher viscosity in the infusion tube 10. In the process of the connecting plates 903 performing staggered squeezing on the infusion tube 10, the control system simultaneously controls the fixing components 7 in the two fixing rings 5 ​​to perform corresponding actions.

[0069] It should be noted that: when the two connecting plates 903 located at the upper end of the supporting platform 4 squeeze the infusion tube 10, the control system controls the pushing member 701 located at the lower end of the supporting platform 4 to further extend, forcing the limiting ring sleeve 705 to expand again. The limiting ring sleeve 705 squeezes the liquid outlet end of the infusion tube 10, so that the inner diameter of the liquid outlet end of the infusion tube 10 is reduced, thereby preventing excessive liquid from flowing out of the liquid outlet end after the infusion tube 10 is compressed.

[0070] When the two connecting plates 903 at the lower end of the support platform 4 squeeze the infusion tube 10, the control system controls the pushing member 701 at the upper end of the support platform 4 to further extend, forcing the limiting ring sleeve 705 to expand again. The limiting ring sleeve 705 squeezes the liquid outlet end of the infusion tube 10, so that the inner diameter of the liquid inlet end of the infusion tube 10 is reduced, thereby preventing the liquid medicine from flowing out of the liquid inlet end after the infusion tube 10 is compressed.

[0071] The present invention arranges an electromagnetic member 904 and an elastic member 902, and obtains the specific state of the connecting plate 903 by detecting the compression amount of the elastic member 902, that is, the state of the infusion tube 10 between the two connecting plates 903. Then, according to the specific state of the infusion tube 10, the electromagnetic member 904 is controlled to perform corresponding actions; when the infusion tube 10 is twisted, the electromagnetic block 9041 forces the elastic member 902 with excessive compression to move relative to the connecting plate 903. During the displacement of the connecting plate 903, on the one hand, the infusion tube 10 is squeezed to improve the infusion accuracy of the infusion tube 10; on the other hand, the twisted part that affects the infusion accuracy is corrected, so that the infusion tube 10 returns to the bottom of the pressing block 3022; when the infusion tube 10 creeps, the electromagnetic block 9041 is continuously turned on and off, forcing the connecting plates 903 on both sides of the infusion tube 10 to squeeze the infusion tube 10, thereby improving the rebound efficiency of the infusion tube 10 and avoiding the delivery of the medicine due to the slow rebound of the infusion tube 10.

[0072] It should be noted that: an alarm is provided inside the human-machine interaction device 18, and a photoelectric sensor is provided at the through slot 20 (the photoelectric sensor is located at the through slot 20 corresponding to the liquid inlet end of the infusion tube 10). The photoelectric sensor is used to detect whether there is liquid medicine inside the infusion tube 10. When the photoelectric sensor detects that there is no liquid medicine inside the infusion tube 10 (that is, the liquid medicine in the liquid medicine bottle has been used up), the alarm is activated. The alarm includes an audible and visual alarm. The alarm sound generated by the alarm can remind medical staff to replace the liquid medicine bottle or disconnect the infusion tube 10 from the interconnection device 16, and at the same time control the drive motor 201 to drive the peristaltic structure 302 to be in Figure 8 state, that is, one of the pressing blocks 3022 completely squeezes the infusion tube 10, and the liquid medicine cannot continue to enter the patient's body through the infusion tube 10, thereby preventing the situation where air enters the patient's body through the infusion tube 10 when medical staff cannot arrive in time.

[0073] The present invention also provides a method for using the constant temperature perfusion system, which comprises the following steps:

[0074] Step 1: First, the infusion tube 10 is passed through the two fixing rings 5 ​​on the carrier 4, and then the two ends of the infusion tube 10 are respectively connected to the external medicine bottle and the connector 15 on the interconnection device 16, so that the assembly of the infusion tube 10 and the catheter 17 is completed;

[0075] Step 2: After the infusion tube 10 and the catheter 17 are assembled, the amount of liquid medicine entering the human body per unit time is calculated according to the patient's weight, and the speed of the driving motor 201 is set on the human-machine interaction device 18 according to the calculated value;

[0076] Step 3: Start the driving motor 201 to run. The driving motor 201 drives the connecting wheel 204 to rotate synchronously through the transmission belt 203. The connecting wheel 204 drives the peristaltic structure 302 to run through the eccentric wheel 301. The peristaltic structure 302 squeezes the infusion tube 10, so that the liquid medicine in the infusion tube 10 can accurately enter the interior of the catheter 17.

[0077] Step 4: During the process of the peristaltic structure 302 squeezing the infusion tube 10, the specific state of the connecting plate 903, that is, the specific state of the infusion tube 10 between the connecting plates 903, is obtained by detecting the compression amount of the elastic member 902, and the electromagnetic member 904 and the fixing component 7 are controlled to perform corresponding specific actions according to the state of the infusion tube 10.

[0078] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0079] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A constant temperature perfusion system with adjustable perfusion pressure for neurointervention, comprising a housing (1), characterized in that: An upper partition (11) is provided inside the shell (1), a driving device (2) is provided on the top of the upper partition (11), an extrusion assembly (3) is provided below the upper partition (11), a lower partition (12) is provided at the bottom of the extrusion assembly (3), the extrusion assembly (3) is movably connected to the lower partition (12), a bearing platform (4) is provided below the lower partition (12), and an infusion tube (10) is provided above the bearing platform (4); A fixing ring (5) is symmetrically arranged on the top of the support platform (4), an electric heating device (13) is arranged inside the fixing ring (5), an annular sleeve (6) is arranged on the inner ring of the fixing ring (5), the annular sleeve (6) fixes the infusion tube (10), a fixing component (7) is arranged on the outer side of the annular sleeve (6), and the fixing component (7) is used to adjust the squeezing force of the fixing ring (5) on the infusion tube (10); A limiting rod (8) is provided between the two fixing rings (5), and an adjusting assembly (9) is provided on each of the two limiting rods (8). The adjusting assembly (9) comprises connecting blocks (901) arranged in an array on the outside of the limiting rods (8), and elastic members (902) are provided on the outside of the connecting blocks (901). A connecting plate (903) is provided at one end of the elastic member (902) away from the connecting block (901), and the connecting plate (903) is located in the area between the two limiting rods (8), and opposite sides of two corresponding connecting plates (903) are in contact with the outside of the infusion tube (10), and an electromagnetic member (904) is provided at the connection between the connecting plate (903) and the elastic member (902); The electromagnetic member (904) comprises an electromagnetic block (9041) arranged on a connecting plate (903); a magnetic block (9042) corresponding to the electromagnetic block (9041) is arranged inside the connecting block (901); and when the electromagnetic block (9041) is activated, it drives the elastic member (902) to perform telescopic movement; The fixing assembly (7) comprises a pushing member (701) arranged inside the limiting rod (8); the telescopic end of the pushing member (701) is provided with an extrusion plate (702); the end of the extrusion plate (702) is provided with an air storage member (703); the outer side of the air storage member (703) is provided with a delivery pipe (704); the other end of the delivery pipe (704) is connected to a limiting ring sleeve (705); the limiting ring sleeve (705) is located on both sides of the annular sleeve (6); The extrusion assembly (3) comprises eccentric wheels (301) arranged in an array, a peristaltic structure (302) being provided at the bottom of the eccentric wheel (301), a transmission shaft (303) being provided on the outer side of the eccentric wheel (301), and the transmission shaft (303) being passed through the eccentric wheel (301); The peristaltic structure (302) is slidably connected to the lower partition (12) and squeezes the outer wall of the infusion tube (10); the transmission shaft (303) is used to drive the eccentric wheel (301) to rotate so as to drive the peristaltic structure (302) to reciprocate up and down; The peristaltic structure (302) includes a pressure rod (3021) slidably connected to the lower partition (12), the pressure rod (3021) is located at the bottom of the eccentric wheel (301), and one end of the bottom of the pressure rod (3021) that passes through the lower partition (12) is connected to a pressure block (3022), and a spring (3023) is provided between the pressure block (3022) and the lower partition (12).

2. A constant temperature perfusion system with adjustable neurointerventional perfusion pressure according to claim 1, characterized in that: The outer sides of the pressing blocks (3022) are in contact with each other. During the rotation of the transmission shaft (303), the eccentric wheel (301) drives the pressing blocks (3022) to perform cosine motion via the pressure rod (3021), and the pressing blocks (3022) press the outer wall of the infusion tube (10).

3. The constant temperature perfusion system with adjustable neurointerventional perfusion pressure according to claim 1, characterized in that: The driving device (2) comprises a driving motor (201) arranged on the top of the upper partition (11); the output shaft of the driving motor (201) is provided with a transmission wheel (202); a transmission belt (203) is provided on the outer side of the transmission wheel (202); the other end of the transmission belt (203) passes through the upper partition (11) and is connected to a connecting wheel (204) arranged at the end of the transmission shaft (303); and an empty groove (205) for the transmission belt (203) to move is opened on the upper partition (11).

4. A constant temperature perfusion system with adjustable neurointerventional perfusion pressure according to claim 3, characterized in that: A bottle stopper piercer (14) is installed at one end of the infusion tube (10), and a needle tube is installed at the other end of the infusion tube (10). The end of the needle tube is connected to a joint (15), and the end of the joint (15) is provided with an interconnection device (16), and the end of the interconnection device (16) is connected to a catheter (17).

5. The constant temperature perfusion system with adjustable pressure for neurointerventional perfusion according to claim 1, characterized in that: A human-machine interaction device (18) is provided on the top of the upper partition (11), and a control system is provided inside the human-machine interaction device (18), and the control system is used to control the movement of electrical components inside the housing (1); A snap-fit ​​frame (19) is provided at the bottom of the shell (1), the bottom of the snap-fit ​​frame (19) is flush with the top of the support platform (4), and through grooves (20) are provided at the connection points between the two ends of the snap-fit ​​frame (19) and the shell (1).

Citation Information

Patent Citations

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    CN215275039U

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    CN112915313A

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