The invention relates to a rapid efficient ammonia nitrogen remover and a preparation method and application thereof. The rapid efficient ammonia nitrogen remover is prepared from the following components in percentage by mass: 5-35% of an oxidant, 5-50% of an inorganic coagulant, 2-40% of an adsorption material, 1-15% of a calcium salt and 1-20% of an effervescent disintegrant. The rapid efficient ammonia nitrogen remover can be dissolved in water, and is free of a residue, free of secondary pollution, the operation is simple and convenient, the time required for purifying the water is short, ammonia nitrogen can be quickly and efficiently removed, and the rapid efficient ammonia nitrogen remover has a certain removal effect on COD, total phosphorus and suspended matters at the same time. The rapid efficient ammonia nitrogen remover integrates oxidation, breakpoint chlorination, coagulating sedimentation, adsorption, pH value control and rapid collapse body dissolution, and the ammonia nitrogen can be quickly and efficiently removed.