Traditional Chinese medicine formula for treating tinea capitis and preparation method thereof

Abstract

The application provides a traditional Chinese medicine formula for treating Meiheqi and a preparation method thereof, wherein the traditional Chinese medicine formula comprises Fructus Mume, Herba Linderae, Ramulus Cinnamomi, light Fufangpi, Angelica sinensis, Radix Ginseng, Phellodendri, Rhizoma Coptidis, Radix Paeoniae Alba, Radix Paeoniae Rubra and Fructus Viticis, and the formula can be adjusted according to the conditions of different patients to adapt to different patients. The traditional Chinese medicine formula has remarkable curative effect on treating Meiheqi by decocting the medicines into a decoction for patients to take.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of traditional Chinese medicine composition for treating plum-pit qi, in particular to a traditional Chinese medicine formula for treating plum-pit qi and a preparation method thereof. BACKGROUND

[0002] Plum-pit qi is a common disease in clinical practice of traditional Chinese medicine, which is characterized by the feeling of foreign body in the throat, like plum-pit, and the symptoms of being unable to spit out or swallow, and the symptoms of being intermittent. It is a classic description of plum-pit qi that "there is a feeling of roasted meat in the throat, and there is a feeling of sputum in the stomach, like roasted meat, which cannot be spit out or swallowed" in "Medical Canon of Golden Mirror". The patient has the feeling of plum-pit obstruction in the throat, and the feeling is obvious when swallowing water, but there is no abnormality or even relief when swallowing food, and no obvious organic lesions are found in the throat or adjacent organs. Modern medicine believes that gastroesophageal reflux disease, throat reflux, pharyngeal neurosis, esophageal motor disorder and dysfunction of upper esophageal sphincter are common causes of plum-pit qi. Chronic pharyngitis, the pharynx is innervated by multiple nerves such as vagus nerve, glossopharyngeal nerve, accessory nerve, trigeminal nerve and cervical plexus, and the nerve endings are widely exposed in the pharynx, acting as sensors, and the abnormal sensitivity is sensitive to various organic lesions, mental factors and other stimuli, so that the receptor potential ion channel on the mucosal surface is opened under the action of the medium, thereby producing abnormal sensation in the pharynx.

[0003] In recent years, with the increase of modern life pressure, the disease prevalence rate increases year by year, which seriously affects the daily work and life quality of patients. The main clinical treatment of western medicine is to use basic prescriptions such as Deanxit, oryzanol and vitamin B1, which can relieve mood, regulate autonomic nervous disorder and improve neuritis, and actively psychological counseling, which has relatively fast effect, but a considerable part of patients have poor effect or no effect, and the disease is easy to relapse after stopping the drug, thereby increasing the patient's psychological burden. The understanding of traditional Chinese medicine for this disease is unique, and the treatment always emphasizes syndrome differentiation and treatment, combination of disease and syndrome, treatment according to the syndrome, less adverse reactions and relatively low price, but many traditional Chinese medicine formulas for treating plum-pit qi at present have the defects of low cure rate and inability to cure. Therefore, it is urgent to research a traditional Chinese medicine formula with good effect for treating plum-pit qi. SUMMARY

[0004] An advantage of the present application is to provide a traditional Chinese medicine formula for treating plum-pit qi and a preparation method thereof, which comprises a plurality of low-cost and non-toxic traditional Chinese medicines, and is used for treating plum-pit qi after scientific blending, has short treatment time and definite curative effect, and is worthy of clinical popularization and application.

[0005] Another advantage of the present application is to provide a traditional Chinese medicine formula for treating pharyngolaryngeal foreign body sensation and a preparation method thereof, wherein the various drugs in the formula cooperate with each other to produce a synergistic effect, and the formula can improve the symptoms related to the digestive tract, repair the related nerves and mucosa of the throat, and has a remarkable effect on most patients with pharyngolaryngeal foreign body sensation.

[0006] Another advantage of the present application is to provide a traditional Chinese medicine formula for treating pharyngolaryngeal foreign body sensation and a preparation method thereof, wherein the Fructus Mume in the formula has an antioxidant and antibacterial effect, and the Fructus Mume can block M receptors, inhibit intestinal peristalsis, relax smooth muscles, and regulate the immune function of patients and improve the immunity of patients during the treatment of pharyngolaryngeal foreign body sensation.

[0007] Another advantage of the present application is to provide a traditional Chinese medicine formula for treating pharyngolaryngeal foreign body sensation and a preparation method thereof, which has low cost, simple preparation method, and is convenient and easy to take for patients.

[0008] Another advantage of the present application is to provide a traditional Chinese medicine formula for treating pharyngolaryngeal foreign body sensation and a preparation method thereof, which can adjust the proportion and components of the drugs in the formula according to the different conditions of different patients, increase or decrease the drugs and the proportion, so that the traditional Chinese medicine formula can adapt to the conditions of different patients, and achieve a better therapeutic effect, a higher cure rate, and a lower recurrence rate.

[0009] According to one aspect of the present application, a traditional Chinese medicine formula for treating pharyngolaryngeal foreign body sensation, i.e., Fengzao Meihuer Decoction, is provided, wherein the Fengzao Meihuer Decoction comprises the following drugs: Fructus Mume, Lindsaea concinna, Ramulus Cinnamomi, light Fufangpi, Angelica sinensis, Radix ginseng, Phellodendri, Coptis deltoidea, Radix Paeoniae Alba, and Vitex negundo.

[0010] Preferably, the proportion of the weight parts of each of the drugs is as follows: Fructus Mume 15-25 parts, Lindsaea concinna 1-3 parts, Ramulus Cinnamomi 4-10 parts, light Fufangpi 5-15 parts, Angelica sinensis 8-15 parts, Radix ginseng 2-8 parts, Phellodendri 5-15 parts, Coptis deltoidea 3-10 parts, Radix Paeoniae Alba 10-30 parts, and Vitex negundo 10-20 parts.

[0011] More specifically, the proportion of the weight parts of each of the drugs is as follows: Fructus Mume 20 parts, Lindsaea concinna 3 parts, Ramulus Cinnamomi 6 parts, light Fufangpi 10 parts, Angelica sinensis 10 parts, Radix ginseng 5 parts, Phellodendri 10 parts, Coptis deltoidea 5 parts, Radix Paeoniae Alba 15 parts, and Vitex negundo 20 parts.

[0012] According to the embodiment of the present application, the traditional Chinese medicine formula in the present application can also include one or more of 20-40 parts of Rabdosia japonica, 5-15 parts of fried Aurantii Fructus, 10-25 parts of Lily, 10-20 parts of Platycladi Medulla, 10-30 parts of Clematis, 5-10 parts of Platycodon, and 5-15 parts of Saposhnikovia.

[0013] According to another aspect of the present application, the present application also provides a preparation method of a traditional Chinese medicine formula for treating phlegm, including the following steps:

[0014] (A) Soaking: each of the medicines included in the traditional Chinese medicine formula in the present application is soaked in clean water for at least 0.5 h;

[0015] (B) Decoction: after the soaking is completed, decoction is performed twice, the medicine juice is poured out after the first decoction is completed, water is added for the second decoction, and the medicine juice of the two decoctions is reserved;

[0016] (C) Mixing: the medicine juice of the two decoctions is mixed evenly; and

[0017] (D) Residue removal and juice collection, and dosage packaging.

[0018] In the above steps, the decoction time is controlled to be 20-40 min each time, boiling is performed during the decoction, after the juice collection, the total amount of the medicine juice is controlled to be in the range of 200-300 mL for the patient to take

[0019] Explanation: in the prescription, Fructus Mume is the monarch drug, which is sour in taste, can astringe the lung, promote intestinal peristalsis, and improve liver function, and can be used for treating chronic cough due to lung deficiency, and heat and thirst due to deficiency, and can tonify the liver, and can also be used for treating liver and stomach.

[0020] Radix Aconiti (diluted slices), Herba Linderae, and Ramulus Cinnamomi are very hot and pungent, which can warm the meridians, dispel cold, warm the channels, assist Yang and transform Qi, and remove the evil of water, dampness, and phlegm.

[0021] Rhizoma Coptidis and Cortex Phellodendri are bitter and cold in taste, which can clear heat and dampness, and have the effects of clearing heat, detoxifying, and purging fire.

[0022] Radix et Rhizoma Ginseng can treat spleen and lung deficiency, cough, and lack of strength, and can promote the production of saliva and quench thirst.

[0023] Angelica can tonify liver blood, and is sweet and heavy in taste, which can tonify blood, and is light and pungent in Qi, so it can also move blood, and has the effect of tonifying and moving.

[0024] Radix Scrophulariae is sweet and bitter in taste, bitter can clear heat, and sweet can tonify and benefit, which is a good medicine for clearing heat and reducing fire, benefiting the throat, cooling blood, red tongue, thirst, bone dryness, and cough, sore throat, and diphtheria, and can also be used for treating liver stagnation and phlegm and blood stasis, and can also be used for treating liver stagnation and phlegm and blood stasis.

[0025] Radix Angelicae Dahuricae is warm and pungent in nature, which has the effects of promoting blood circulation, removing pus, reducing swelling, and relieving pain.

[0026] Mandarin orange nature cold, bitter, with the effect of dispelling wind and heat, clear and benefit the eyes, dispel wind and relieve pain.

[0027] Bitter, sweet, sour, warm, with the effect of regulating qi, wide, stagnation and swelling, treatment of phlegm, labor and cough, and stomach distension, dry throat, not thirsty.

[0028] Wind flavor, sweet, warm, with the effect of dispelling wind and relieving the surface, removing dampness and relieving pain, stopping convulsions.

[0029] Narrow lung, expelling phlegm, pus, clear throat, treatment of cough, sore throat, hoarse, chest tightness.

[0030] Xiangcha herb can clear heat and dampness, promote blood circulation, eliminate blood stasis, and has the effect of detoxification and swelling on sore throat and throat.

[0031] Lily can clear lung and relieve cough, clear heart and calm the mind, and tonify the middle and benefit qi.

[0032] Cypress seed can nourish the heart and calm the mind, moisten the intestines and defecate, and treat yin deficiency, insomnia, palpitation and night sweating.

[0033] Kusnezoff monkshood root can dispel wind and dampness and relieve pain, and can also promote blood circulation and unblock collaterals. It is good at dispelling wind and dampness, unblocking collaterals, and eliminating phlegm and water or softening and resolving masses.

[0034] This prescription is the mutual cooperation of monarch, minister, assistant and messenger in traditional Chinese medicine. It can improve the symptoms of the digestive tract by using bitter and sweet, considering both deficiency and excess, using both warm and clear, and regulating liver and spleen. With the help of Shengshai and the warmth of kidney yang, the spleen yang is naturally vigorous.

[0035] A large dose of plum not only contracts the liver and discharges the liver, but also acid and sweet yin to nourish the liver to control its yang. On the one hand, it helps ginseng and angelica to supplement deficiency, and on the other hand, it helps coptis and phellodendron to treat diarrhea, and also controls the excessive dispersion of zingiber and piper. On this basis, the addition of white yarrow and mandarin orange, which is a pair of dispelling wind medicine, can ascend and open the channels and reach the throat disease, open the lung qi and resolve phlegm and resolve phlegm. The combination of these medicines and ginseng can clear the upper and warm the lower, regulate yin and yang, resolve phlegm and resolve phlegm. It is effective for most patients with plum pit qi for a long time, and is worth further promotion and application in clinic.

[0036] Modern pharmacological studies have confirmed that Wumei, Xixin, Guizhi, Danfupian, Danggui, Shengsaishen, Huangbai, Chuanlian and other drugs have the effects of anti-inflammatory response, regulating immune function, promoting the recovery of gastrointestinal function, repairing intestinal mucosal barrier, regulating intestinal flora, antioxidant damage, analgesia, etc. Their inhibitory effect increases with the increase of the dose. Among them, Baizhi and Manjingzi are wind-removing drugs. Studies have found that Baizhi extract has the effects of anti-allergy and vasodilation, and can increase the content of central dopamine and 5-hydroxytryptamine to play the role of analgesia and tranquilization. Manjingzi extract has the effects of analgesia, anti-inflammatory and vasodilation. The combination of the two wind-removing drugs can raise the clear and unblock the orifices, guide the drugs upward, and directly reach the throat disease, and jointly repair the related nerve function of the throat.

[0037] Studies have shown that mental and psychological factors, self-nerve function disorder, esophageal sensory abnormalities, esophageal motility disorders and gastrointestinal diseases are closely related to the occurrence and development of Meini. Based on the network pharmacology method and molecular docking technology, the active chemical components contained in the main prescription Wumei Pill in the prescription are mainly used for the key genes of smooth muscle, liver, lung, thyroid, bronchial epithelial cells and other organs. Not only does it verify the composition concept of “cold and heat combination, attack and tonification combination” from the immunological point of view, but also highlights the immune regulation effect of Wumei Pill, and promotes the recovery of gastrointestinal function and esophageal motility disorders. Modern pharmacological studies have shown that Wumei Pill can promote inflammation and mucosal damage repair, regulate gastrointestinal function, and components such as ursolic acid in Wumei have exact antibacterial, antioxidant and antitumor effects. Wumei water extraction and Wumei extract have the effects of astringent intestine and antidiarrhea. Studies on Wumei extract on the movement of rabbit isolated small intestine have found that by blocking M receptors, it can inhibit intestinal peristalsis and reduce smooth muscle, and play the role of relaxing smooth muscle. Because of the above-mentioned pathologies, the combination of drugs is selected for the treatment of Meini. DETAILED DESCRIPTION

[0038] The following description is used to disclose the present application so that those skilled in the art can implement the present application. The preferred embodiments in the following description are only as examples, and other obvious modifications can be thought by those skilled in the art. The basic principles of the present application defined in the following description can be applied to other embodiments, modifications, improvements, equivalents and other technical solutions without departing from the spirit and scope of the present application.

[0039] The weight ratio of each of the drugs in the traditional Chinese medicine formula of the present application is as follows: Wumei 15-25 parts, Xixin 1-3 parts, Guizhi 4-10 parts, Danfupian 5-15 parts, Danggui 8-15 parts, Shengsaishen 2-8 parts, Huangbai 5-15 parts, Chuanlian 3-10 parts, Yuanshen 10-30 parts, Baizhi 10-15 parts and Manjingzi 10-20 parts.

[0040] Based on the symptoms of different patients, highly targeted and personalized treatment plans can be provided to adapt to the specific conditions of the patients and improve the treatment effect. Therefore, based on the above-mentioned traditional Chinese medicine formula, it can be added to or modified so that the traditional Chinese medicine formula of the present invention can also include one or more of the following: 20-40 parts of fragrant tea herb, 5-15 parts of stir-fried bitter orange peel, 10-25 parts of lily bulb, 10-20 parts of arborvitae seed, 10-30 parts of clematis root, 5-10 parts of platycodon root, and 5-15 parts of saposhnikovia root. Specific implementation methods are as follows:

[0041] Example 1

[0042] The weight proportions of each of the drugs in the traditional Chinese medicine formula for treating globus hystericus provided by this invention are as follows: 20 parts of dried plum, 3 parts of asarum, 6 parts of cinnamon twig, 10 parts of prepared aconite root, 10 parts of angelica root, 5 parts of raw ginseng, 10 parts of phellodendron bark, 5 parts of coptis root, 15 parts of scrophularia root, 15 parts of angelica dahurica, and 20 parts of vitex fruit.

[0043] Example 2

[0044] 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts lightly ground aconite root, 10 parts angelica root, 5 parts sun-dried ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 30 parts fragrant tea vegetable, and 10 parts stir-fried immature bitter orange peel.

[0045] Example 3

[0046] 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts lightly ground aconite root, 10 parts angelica root, 5 parts sun-dried ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 10 parts stir-fried immature bitter orange peel, 15 parts lily bulb, and 12 parts cypress seed.

[0047] Example 4

[0048] 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts lightly ground aconite root, 10 parts angelica root, 5 parts sun-dried ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 15 parts stir-fried immature bitter orange peel, and 20 parts clematis root.

[0049] Example 5

[0050] 20 parts of dried plum, 3 parts of asarum, 6 parts of cinnamon twig, 10 parts of lightly ground aconite root, 10 parts of angelica root, 5 parts of sun-dried ginseng, 10 parts of phellodendron bark, 5 parts of coptis root, 15 parts of scrophularia root, 15 parts of angelica root, 20 parts of vitex fruit, 6 parts of platycodon root, and 10 parts of saposhnikovia root.

[0051] Example 6

[0052] 20 parts of dried plum, 3 parts of asarum, 6 parts of cinnamon twig, 10 parts of lightly ground aconite root, 10 parts of angelica root, 5 parts of sun-dried ginseng, 10 parts of phellodendron bark, 5 parts of coptis root, 15 parts of scrophularia root, 15 parts of angelica root, 20 parts of vitex fruit, 10 parts of saposhnikovia root, and 12 parts of stir-fried immature bitter orange peel.

[0053] Example Seven

[0054] Fructus mume 15 parts, Asarum 5 parts, Ramulus cinnamomi 4 parts, light Fufang tablet 15 parts, Angelica 5 parts, raw and dried ginseng 6 parts, Phellodendron 8 parts, Rhizoma Corydalis 8 parts, Radix Paeoniae Alba 10 parts, Vitex 20 parts, Platycodon 8 parts, Radix Sophorae 15 parts, and Fried Aurantii Fructus 10 parts.

[0055] Example Eight

[0056] Fructus mume 25 parts, Asarum 3 parts, Ramulus cinnamomi 10 parts, light Fufang tablet 8 parts, Angelica 15 parts, raw and dried ginseng 2 parts, Phellodendron 15 parts, Rhizoma Corydalis 5 parts, Radix Paeoniae Alba 10 parts, Vitex 20 parts, Baihe 15 parts, and Fried Aurantii Fructus 15 parts.

[0057] Example Nine

[0058] Fructus mume 20 parts, Asarum 2 parts, Ramulus cinnamomi 6 parts, light Fufang tablet 10 parts, Angelica 12 parts, raw and dried ginseng 8 parts, Phellodendron 15 parts, Rhizoma Corydalis 3 parts, Radix Paeoniae Alba 25 parts, Vitex 10 parts, and Fried Aurantii Fructus 20 parts.

[0059] Example Ten

[0060] Fructus mume 25 parts, Asarum 3 parts, Ramulus cinnamomi 6 parts, light Fufang tablet 10 parts, Angelica 12 parts, raw and dried ginseng 5 parts, Phellodendron 10 parts, Rhizoma Corydalis 6 parts, Radix Paeoniae Alba 20 parts, Vitex 15 parts, and Radix Tripterygii 30 parts.

[0061] It is worth mentioning that the above examples are only as examples, and those skilled in the art can understand that the above formula can be added and subtracted to adapt to different patients.

[0062] The traditional Chinese medicine of the above examples of the application is prepared by the following decoction method, and the decoction is used for patients to take.

[0063] 1. The preparation method of the traditional Chinese medicine formula provided by the application, comprising the following steps:

[0064] (1) soaking: first, all the medicines in the traditional Chinese medicine formula of the application are soaked in clean water for more than 0.5 h, and all the medicines are immersed in water during soaking;

[0065] (2) decoction: after soaking is completed, decoction is carried out, and the total decoction is carried out twice, first decoction: after water is boiled for 20 min, the medicine juice is poured out, and then second decoction is carried out; second decoction: water is added again, and after boiling for 30 min, the medicine juice is poured out;

[0066] (3) mixing: the medicine juice of the first decoction and the second decoction is mixed together and stirred to be uniformly mixed; and

[0067] (4) The total amount of decoction after mixing is controlled within 400 mL, preferably within 300 mL. When the decoction is relatively large, the residue can be removed to collect the juice.

[0068] 2. Method of taking: take twice a day, in the morning and evening.

[0069] 3. Time of taking: take about 1.5 hours after meals.

[0070] 4. Matters needing attention:

[0071] (1) The time for each decoction is 20-40 minutes.

[0072] (2) If the total amount of decocted juice is too much, the residue can be removed and the soup can be collected on the fire to 300 mL or less.

[0073] (3) Patients with nausea, vomiting, and loss of appetite should try to control the total amount of juice to less than 300 mL, and can use the method of taking small amounts of medicine several times a day.

[0074] (4) When the weather is hot, please put the decocted juice in the refrigerator, and take it out and warm it up before taking it.

[0075] 5. If nausea, vomiting, or skin allergy occurs during the taking process, stop taking the medicine immediately and seek medical advice.

[0076] In order to further investigate the clinical efficacy and safety of the traditional Chinese medicine formula provided in the present application and the traditional Chinese medicine formula for treating Meiqi in the above examples, the efficacy of the present application drug was clinically observed on 52 Meiqi patients.

[0077] All cases were diagnosed as Meiqi according to the "Diagnosis and Efficacy Standard of TCM Syndromes" issued by the State Administration of Traditional Chinese Medicine.

[0078] The beneficial effects of the present application will be illustrated below in combination with clinical experimental data:

[0079] 1. General information:

[0080] The present application collected 52 cases of Meiqi patients who came to the hospital for treatment from August 2021 to September 2022. Among them, there were 12 male cases and 40 female cases (male: female = 12:40). The youngest was 37 years old, the oldest was 74 years old, and the average age was 56.75 years old, of which the age range was: (30, 40] = 4 people, accounting for 7.69%; (40, 50] = 7 people, accounting for 13.46%; (50, 60] = 25 people, accounting for 48.08%; (60, 70] = 15 people, accounting for 28.85%; (70, 80] = 2 people, accounting for 3.85%.

[0081] 2. Diagnosis standard:

[0082] Symptoms: often as repeated throat obstruction, throat have a sense of foreign body, swallow not down, spit not out, belching frequently, abnormal stool, pulse string slip. To the throat, esophagus and other related organ examination, there is no organic lesions, exclude the possibility of throat and esophageal mass.

[0083] Western medicine diagnosis: chronic pharyngitis, chronic superficial gastritis, etc.

[0084] TCM diagnosis: plum kernel qi; stomach disease; dialectical: upper heat and lower cold syndrome.

[0085] 3. Treatment method:

[0086] The traditional Chinese medicine formula of the application is decocted and taken, taken after breakfast and dinner, seven doses for a course of treatment, and re-examination or follow-up after the course of treatment.

[0087] 4. Efficacy criteria:

[0088] Significant: pharyngeal foreign body sensation disappeared, no recurrence after stopping medication.

[0089] Effective: pharyngeal foreign body sensation is significantly reduced, and the throat feels relaxed, but sometimes there is still a slight foreign body sensation.

[0090] Ineffective: pharyngeal foreign body sensation still exists, and foreign body sensation is not reduced.

[0091] 5. Treatment effect:

[0092] 52 cases of plum kernel qi patients were treated by the above treatment method, and the treatment conditions are shown in Table 1.

[0093] Table 1 Treatment conditions of 52 cases of plum kernel qi patients

[0094] Number of cases n Significant n (%) Effective n (%) Ineffective n (%) Total effective n (%) 52 39(75％) 9((17.31％)) 4(7.69％) (92.31)

[0095] It can be seen that the traditional Chinese medicine formula of the application has significant effect in the treatment of plum kernel qi, and is suitable for the treatment of plum kernel qi patients. The beneficial effects of the traditional Chinese medicine formula provided by the application are further illustrated below in combination with clinical specific cases.

[0096] Typical case 1

[0097] Peng, female, 59 years old, retired. Initial diagnosis on July 10, 2022. Complaint: repeated throat obstruction for more than half a year, aggravated for 1 month. The patient had a throat foreign body sensation after arguing with family members half a year ago, which was not paid attention to. One month ago, the symptoms worsened, and the throat was blocked, the gas rushed to the chest, accompanied by stomach fullness, acid reflux, alternating constipation and diarrhea, cold limbs, poor sleep, pale red tongue, thin white fur, and thin slippery pulse. Gastroscopy showed chronic atrophic gastritis with mild intestinal metaplasia. Western medical diagnosis: 1. Pharyngeal neurosis, 2. Chronic atrophic gastritis. TCM diagnosis: 1. Meiguoqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguo Decoction. Medicines: 20 parts of Fructus Mume, 3 parts of Asarum, 6 parts of Ramulus Cinnamomi, 10 parts of Dried Poria (first added), 10 parts of Angelica sinensis, 5 parts of Radix Pseudostellariae, 10 parts of Phellodendri, 5 parts of Radix et Rhizoma Corydalis, 15 parts of Radix Pseudostellariae, 15 parts of Radix Angelicae Dahuricae, 20 parts of Fructus Viticis, 30 parts of Herba Rabdosiae, 10 parts of Fructus Aurantii Immaturus. 7 doses of water decoction were taken, and the patient took 6 pills of Dailixin every day. On July 17, the patient felt better, and there was no obvious foreign body sensation in the throat, no gas rushing, occasional stomach fullness, less severe than before, no acid reflux, dry stool, cold limbs, poor sleep, pale red tongue, thin white fur, and thin slippery pulse. The patient continued to take the same prescription for 7 doses. One week later, the patient called and said that all symptoms were cured.

[0098] Typical case 2

[0099] Zhang, female, 62 years old, retired. Initial diagnosis on July 22, 2022. Complaint: repeated throat obstruction for 3 years. The patient had repeated stomach fullness for 3 years, and felt that the throat was blocked, which could not be spit out or swallowed. The patient had a mouth ulcer, and the stool was loose. The tongue was pale red, the tongue fur was white and greasy, and the pulse was thin and slippery. Western medical diagnosis: chronic superficial gastritis. TCM diagnosis: 1. Meiguoqi 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguo Decoction. Medicines: 20 parts of Fructus Mume, 3 parts of Asarum, 6 parts of Ramulus Cinnamomi, 10 parts of Dried Poria (first added), 10 parts of Angelica sinensis, 5 parts of Radix Pseudostellariae, 10 parts of Phellodendri, 5 parts of Radix et Rhizoma Corydalis, 15 parts of Radix Pseudostellariae, 15 parts of Radix Angelicae Dahuricae, 20 parts of Fructus Viticis, 10 parts of Fructus Aurantii Immaturus, 15 parts of Fritillaria, 12 parts of Semen Platycladi. 7 doses of water decoction were taken, and the patient took 6 pills of Dailixin every day. On July 17, the patient felt better, and there was no obvious foreign body sensation in the throat, no gas rushing, occasional stomach fullness, less severe than before, no acid reflux, dry stool, cold limbs, poor sleep, pale red tongue, thin white fur, and thin slippery pulse. The patient continued to take the same prescription for 7 doses. One week later, the patient called and said that all symptoms were cured.

[0100] Typical case 3

[0101] Li, female, 49 years old. Initial diagnosis on March 15, 2022. Complaint: Recurrent throat congestion for more than a year. There is a foreign body obstruction in the throat, which cannot be spit out or swallowed. Dry mouth, hot and stuffy, mouth sores, loose stools, cold limbs, poor sleep. Pale red tongue, thick white tongue fur, thin and slippery pulse. Discontinued use of western medicine for treating pharyngitis for one year, and the symptoms recurred. Western medical diagnosis: chronic pharyngitis. Traditional Chinese medical diagnosis: 1. Meiguqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment principle: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguqi Decoction. Medicines: Fructus Mume 20 parts, Radix et Rhizoma Linderae 3 parts, Ramulus Cinnamomi 6 parts, Dried Poria 10 parts, Radix Angelicae Sinensis 10 parts, Radix et Rhizoma Ginseng 5 parts, Cortex Phellodendri 10 parts, Radix et Rhizoma Coptidis 5 parts, Radix et Rhizoma Polygonati 15 parts, Radix Angelicae Pubescentis 15 parts, Fructus Viticis 20 parts, Radix Platycodonis 6 parts, and Radix Saposhnikoviae 10 parts. 7 doses of water decoction, taken warm after breakfast and dinner. Second visit: throat obstruction and sleep improved, continued taking the original prescription for 7 doses. Third visit: all symptoms improved.

[0102] Typical case 4

[0103] Liu, female, 57 years old, retired. Initial diagnosis on November 12, 2021. Complaint: Recurrent throat obstruction for more than half a year, aggravated for two months. Family relationship is not harmonious, often depressed, half a year ago after getting angry, throat obstruction appeared, which cannot be swallowed or spit out, not taken seriously, two months ago, the symptoms aggravated, like a foreign body obstruction in the throat, gas rushing up to the chest, chest tightness and pain, frequent belching, accompanied by stomach fullness, acid reflux, cold limbs, poor sleep, pale red tongue, thin white tongue fur, thin and slippery pulse. After hospital examination, there is no abnormality in the throat and esophagus. Western medical diagnosis: chronic superficial gastritis. Traditional Chinese medical diagnosis: 1. Meiguqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment principle: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguqi Decoction. Medicines: Fructus Mume 20 parts, Radix et Rhizoma Linderae 3 parts, Ramulus Cinnamomi 6 parts, Dried Poria 10 parts, Radix Angelicae Sinensis 10 parts, Radix et Rhizoma Ginseng 5 parts, Cortex Phellodendri 10 parts, Radix et Rhizoma Coptidis 5 parts, Radix et Rhizoma Polygonati 10 parts, Radix Angelicae Pubescentis 15 parts, Fructus Viticis 20 parts, Fried Fructus Aurantii 15 parts, and Radix et Rhizoma Stephaniae Tetrandrae 20 parts. 7 doses of water decoction, taken warm after breakfast and dinner. November 20, re-visit, the patient felt that the above symptoms improved, no obvious foreign body sensation in the throat, no gas rushing up, occasional chest tightness, acid reflux, cold limbs, better sleep than before, pale red tongue, thin white tongue fur, thin and slippery pulse, continued taking the original prescription for 7 doses. After one week, the patient reported that all symptoms were cured, and there was no recurrence within half a year.

[0104] Typical case 5

[0105] Lin, male, 63 years old, retired. Initial diagnosis on May 6, 2022. Complaint: repeated throat congestion for 4 years. The patient has no history of smoking. Four years ago, he experienced repeated stomach fullness, a feeling of obstruction in the throat, difficulty in swallowing, dry mouth, poor sleep, and other symptoms. Gastroscopy showed chronic superficial gastritis and esophageal mucosa changes. Pathology: mild chronic non-atrophic gastritis, HP (-). Pale red tongue, white and dry tongue fur, and thin and slippery pulse. Western medical diagnosis: pharyngeal neurosis. Traditional Chinese medical diagnosis: 1. Meiguqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguqi Decoction. Medicines: Fructus Mume 25 parts, Asarum 3 parts, Cinnamomum 10 parts, Dried Poria 8 parts (first), Angelica 15 parts, Ginseng 2 parts, Amur Cork Tree 15 parts, Coptis 5 parts, Yuan Shen 20 parts, Bai Zhi 10 parts, Vitex 20 parts, Lily 15 parts, Xiangcha Cai 20 parts, and Fried Citron 15 parts. 7 doses of water decoction, taken warm after breakfast and dinner. Second visit: throat obstruction and sleep improved, original prescription continued for 14 doses for two courses, two weeks later, no visit, telephone follow-up, symptoms of foreign body sensation disappeared, normal bowel movements.

[0106] Typical Case 6

[0107] Ji, female, 51 years old. Initial diagnosis on April 20, 2022. Complaint: repeated throat congestion for more than two years. The patient feels a sense of obstruction and adhesion in the throat, difficulty in swallowing, and often feels a foreign body in the throat, presses the throat with hands, coughs and clears the throat, swallows water, dry mouth, and other symptoms. After examination in the hospital, there is no organic lesion in the throat and esophagus, and the possibility of laryngeal and esophageal tumors is excluded. Pale red tongue, white and greasy tongue fur, and thin and slippery pulse. Western medical diagnosis: pharyngeal neurosis. Traditional Chinese medical diagnosis: 1. Meiguqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguqi Decoction. Medicines: Fructus Mume 20 parts, Asarum 3 parts, Cinnamomum 6 parts, Dried Poria 10 parts (first), Angelica 10 parts, Ginseng 5 parts, Amur Cork Tree 10 parts, Coptis 5 parts, Yuan Shen 12 parts, Bai Zhi 15 parts, Vitex 20 parts, Wind-Protecting Herb 10 parts, and Fried Citron 12 parts. 7 doses of water decoction, taken warm after breakfast and dinner. Second visit: throat obstruction and dry mouth symptoms improved, original prescription continued for 7 doses. Third visit: symptoms improved.

[0108] Typical Case 7

[0109] Zhang, female, 74 years old. Initial diagnosis on July 3, 2022. Complaint of recurrent throat obstruction for more than 2 years. Present history: often feel that the throat is blocked, gas rushes up to the chest, accompanied by stomach fullness, chronic atrophic gastritis with severe intestinalization, cold limbs, poor sleep, pale red tongue, thin white fur, thin and slippery pulse. Western medical diagnosis: 1. Pharyngeal neurosis, 2. Chronic atrophic gastritis. TCM diagnosis: 1. Meiguqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment principle: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguqi Decoction. Medicines: Wu Mei 20 parts, Xixin 3 parts, Guizhi 6 parts, Danfupian (first entered) 10 parts, Danggui 10 parts, Shengsaishen 5 parts, Huangbai 10 parts, Chuanlian 5 parts, Yuanshen 25 parts, Baizhi 15 parts, Manjingzi 20 parts, Xiangchacai 30 parts, Chaozhishi 10 parts. 7 doses of water decoction, warm after breakfast and dinner, after taking medicine, the symptoms are improved.

[0110] Typical case 8

[0111] Shu, female, 58 years old. Initial diagnosis on July 3, 2022. Complaint of throat obstruction, swallowing is not easy. Present history: sore throat, constipation, cold limbs, poor sleep, pale red tongue, thin white fur, thin and slippery pulse. Western medical diagnosis: pharyngeal neurosis. TCM diagnosis: 1. Meiguqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment principle: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguqi Decoction. Medicines: Wu Mei 20 parts, Xixin 3 parts, Guizhi 6 parts, Danfupian (first entered) 10 parts, Danggui 10 parts, Shengsaishen 5 parts, Huangbai 10 parts, Chuanlian 5 parts, Yuanshen 15 parts, Baizhi 15 parts, Manjingzi 20 parts, Xiangchacai 30 parts, Chaozhishi 10 parts. 7 doses of water decoction, warm after breakfast and dinner, after taking medicine, the symptoms are improved.

[0112] Typical case 9

[0113] Wang, female, 52 years old. Initial diagnosis on June 26, 2022. Complaint of throat obstruction. Present history: sore throat, constipation, cold limbs, poor sleep, original esophagitis, gastritis, erosion, chronic diarrhea, pale white tongue fur, thin and slippery pulse, western medical diagnosis: 1. Pharyngeal neurosis, 2. Gastritis. TCM diagnosis: 1. Meiguqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment principle: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguqi Decoction. Medicines: Wu Mei 20 parts, Xixin 3 parts, Guizhi 6 parts, Danfupian (first entered) 10 parts, Danggui 10 parts, Shengsaishen 5 parts, Huangbai 10 parts, Chuanlian 5 parts, Yuanshen 15 parts, Baizhi 15 parts, Manjingzi 20 parts, Xiangchacai 30 parts, Chaozhishi 10 parts, Weilingxian 10 parts. 7 doses of water decoction, warm after breakfast and dinner. Re-diagnosis on July 3, 2022, the upper symptoms are improved, and Fengzao Meiguqi Decoction is continued for 7 doses.

[0114] Typical case 10

[0115] Zhu, female, 65 years old. Initial diagnosis on April 12, 2022. Complaints of throat obstruction. Current medical history: gastritis with erosion, abdominal pain, acid reflux, pale red tongue fur, thin and slippery pulse, liver and stomach heat, stomach pain sometimes, Western medical diagnosis: 1. pharyngeal neurosis, 2. gastritis. TCM diagnosis: 1. Meiguoqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguo Decoction. Medicines: Fructus Mume 20 parts, Asarum 3 parts, Ramulus Cinnamomi 6 parts, Dried Poria 10 parts, Angelica 10 parts, Radix Ginseng 5 parts, Cortex Phellodendri 10 parts, Cortex Cinnamomi 5 parts, Radix Paeoniae Alba 15 parts, Fructus Chaenomelis 20 parts, Herba Rabdosiae 40 parts, Radix Platycodi 10 parts, Radix Stephaniae Tetrandrae 5 parts. 7 doses of water decoction, warm after breakfast and dinner. Re-examination on April 20, 2022, upper symptoms improved, still dry heat, dizziness, aversion to cold, stomach cold and diarrhea, chronic gastritis, Fengzao Meiguo Decoction for 7 more doses, symptoms relieved.

[0116] Typical case 11

[0117] Dai, female, 57 years old. Initial diagnosis on June 12, 2022. Complaints of throat obstruction. Current medical history: chronic atrophic gastritis with mild intestinal metaplasia, throat obstruction like phlegm obstruction, epigastric fullness and discomfort, greasy and pale tongue fur, thin and slippery pulse, Western medical diagnosis: 1. pharyngeal neurosis, 2. chronic atrophic gastritis. TCM diagnosis: 1. Meiguoqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguo Decoction. Medicines: Fructus Mume 20 parts, Asarum 3 parts, Ramulus Cinnamomi 6 parts, Dried Poria 10 parts, Angelica 10 parts, Radix Ginseng 5 parts, Cortex Phellodendri 10 parts, Cortex Cinnamomi 5 parts, Radix Paeoniae Alba 15 parts, Fructus Chaenomelis 20 parts, Herba Rabdosiae 30 parts, Fried Aurantii Fructus 10 parts. 7 doses of water decoction, warm after breakfast and dinner. Re-examination on June 19, 2022, upper symptoms improved, still throat obstruction, Fengzao Meiguo Decoction for 7 more doses. Re-examination on June 28, 2022, upper symptoms improved, still pharyngeal discomfort, pale and greasy tongue fur, Fengzao Meiguo Decoction for 14 more doses, later telephone follow-up, symptoms relieved.

[0118] Typical case 12

[0119] Chen, female, 56 years old. Initial diagnosis on July 3, 2022. Complaints of pharyngeal obstruction and difficulty in expectoration for more than 3 years. Present illness: irritable, cold limbs, white and greasy tongue, pale red, thin and slippery pulse, Western medicine diagnosis: pharyngeal neurosis. TCM diagnosis: 1. Meiguangqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguang Decoction. Medicines: 20 parts of plum, 3 parts of asarum, 6 parts of cassia twig, 10 parts of light fritillary tablet (first), 10 parts of angelica, 5 parts of raw and dried ginseng, 10 parts of golden cypress, 5 parts of Sichuan corydalis, 15 parts of Yuan Shen, 15 parts of white magnolia, 20 parts of vitex, 30 parts of Xiangchaecai, 10 parts of fried bitter orange. 7 doses of water decoction, warm after breakfast and dinner, after taking medicine, the upper symptoms improved, pharyngeal obstruction relieved. The original prescription continued for 7 doses, the spirit gradually improved, and the diet increased.

[0120] Typical case 13

[0121] Lin, male, 53 years old. Initial diagnosis on June 2, 2022. Complaints of pharyngeal obstruction. Present illness: fullness in the epigastric region, repeated attacks, belching and dry stool, poor sleep, thin white tongue, pale red, thin and slippery pulse, dry mouth, history of gastritis, Western medicine diagnosis: 1. Pharyngeal neurosis, 2. Gastritis. TCM diagnosis: 1. Meiguangqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguang Decoction. Medicines: 20 parts of plum, 3 parts of asarum, 6 parts of cassia twig, 10 parts of light fritillary tablet (first), 10 parts of angelica, 5 parts of raw and dried ginseng, 10 parts of golden cypress, 5 parts of Sichuan corydalis, 15 parts of Yuan Shen, 15 parts of white magnolia, 20 parts of vitex, 30 parts of Xiangchaecai, 10 parts of fried bitter orange. 7 doses of water decoction, warm after breakfast and dinner. Re-diagnosis on June 9, 2022, upper symptoms improved, continue with Fengzao Meiguang Decoction for 7 days. Re-diagnosis on June 18, 2022, upper symptoms improved, still have pharyngeal obstruction, eyes jumping, poor sleep, dry and loose stool, dry and cold, thin and white tongue, pale red, thin and slippery pulse, continue with Fengzao Meiguang Decoction for 7 days.

[0122] Typical case 14

[0123] Lü, female, 37 years old, initial diagnosis on June 26, 2022. Complaints of pharyngeal obstruction. Present illness: irritable, pruritus of the vulva, yellowish leukorrhea, thin white tongue, thin and slippery pulse. Western medicine diagnosis: pharyngeal neurosis. TCM diagnosis: 1. Meiguangqi, 2. Weipibing. Syndrome differentiation: upper heat and lower cold. Treatment: clearing the upper and warming the lower, regulating yin and yang. Prescription: Fengzao Meiguang Decoction. Medicines: 20 parts of plum, 3 parts of asarum, 6 parts of cassia twig, 10 parts of light fritillary tablet (first), 10 parts of angelica, 5 parts of raw and dried ginseng, 10 parts of golden cypress, 5 parts of Sichuan corydalis, 15 parts of Yuan Shen, 15 parts of white magnolia, 20 parts of vitex, 30 parts of Xiangchaecai, 10 parts of fried bitter orange. 7 doses of water decoction, warm after breakfast and dinner. Re-diagnosis on July 3, 2022, upper symptoms improved, continue with Fengzao Meiguang Decoction for 7 days.

[0124] Typical Case 15

[0125] Mr. Han, male, 61 years old. First visit on July 1, 2022. Chief complaint: throat obstruction and discomfort. Present illness: atrophic gastritis with erosion, epigastric fullness, chronic pharyngitis, a feeling of something stuck in the throat, thin white and greasy tongue coating, pale red tongue body, wiry, thready and slippery pulse. Western medicine diagnosis: 1. Pharyngeal neurosis, 2. Chronic atrophic gastritis. Traditional Chinese medicine diagnosis: 1. Globus hystericus, 2. Stomach fullness. Differentiation of syndromes: Upper heat and lower cold syndrome. Treatment principle: Clear the upper and warm the lower, harmonize yin and yang. Prescription: Modified Fengzao Meihe Tang (Wind-drying Globus Hystericus Decoction). Ingredients: 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts lightly ground aconite root (added first), 10 parts angelica root, 5 parts raw ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 30 parts fragrant tea vegetable, 10 parts stir-fried immature bitter orange peel. Seven doses were decocted in water and taken warm after breakfast and dinner. Also, 6 tablets of Duloxetine* were taken, one tablet daily. Second visit: All symptoms improved.

[0126] Typical Case 16

[0127] Ms. Zhao, female, 49 years old. First visit on August 12, 2021. Chief complaint: Difficulty swallowing, belching and acid reflux for more than 4 months. Present illness: Difficulty swallowing, belching and acid reflux, white and greasy tongue coating with pale red tongue body, wiry and thready pulse. Western medicine diagnosis: Pharyngeal neurosis. Traditional Chinese medicine diagnosis: 1. Globus hystericus, 2. Stomach fullness syndrome. Differentiation of syndrome: Upper heat and lower cold syndrome. Treatment principle: Clear the upper and warm the lower, harmonize yin and yang. Prescription: Modified Fengzao Meihe Tang (Wind-drying Globus Hystericus Decoction). Ingredients: 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts prepared aconite root (added first), 10 parts angelica root, 5 parts raw ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 30 parts fragrant tea vegetable, 10 parts stir-fried immature bitter orange peel. 7 doses to be decocted in water and taken warm after breakfast and dinner. The patient returned for a follow-up visit on August 19, 2021, and the symptoms had improved. Seven doses of Fengzao Meihe Decoction were prescribed. On August 26, 2021, the patient returned for a follow-up visit, and the symptoms of throat obstruction persisted. Seven doses of Fengzao Meihe Decoction were prescribed again. On September 3, 2021, the patient returned for a follow-up visit, and the symptoms had improved. Seven doses of Fengzao Meihe Decoction were prescribed again.

[0128] Typical Case 17

[0129] Ms. Wang, female, 63 years old. First visit on July 3, 2022. Chief complaint: throat obstruction and discomfort. Present illness: dry mouth and throat, irritability, occasional diarrhea, thin yellow and greasy tongue coating, red tongue body, wiry, thready and slippery pulse. Western medicine diagnosis: pharyngeal neurosis. Traditional Chinese medicine diagnosis: 1. Globus hystericus, 2. Stomach fullness syndrome. Differentiation of syndromes: upper heat and lower cold syndrome. Treatment principle: clear the upper and warm the lower, harmonize yin and yang. Prescription: Modified Fengzao Meihe Tang (Wind-drying Globus Hystericus Decoction). Ingredients: 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts prepared aconite root (added first), 10 parts angelica root, 5 parts raw ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 30 parts fragrant tea vegetable, 10 parts stir-fried immature bitter orange peel. 7 doses to be decocted in water and taken warm after breakfast and dinner.

[0130] Typical Case 18

[0131] Mr. Ding, male, 54 years old, first visit on September 1, 2021. Chief complaint: cough with phlegm, and a feeling of obstruction in the throat for over a year. Present illness: loose stools, abdominal distension, pale red tongue with a thin white coating, and a thready, wiry, and slippery pulse. Western medicine diagnosis: pharyngeal neurosis. Traditional Chinese medicine diagnosis: 1. Globus hystericus, 2. Stomach fullness syndrome. Differentiation of syndromes: upper heat and lower cold syndrome. Treatment principle: clear the upper and warm the lower, harmonize yin and yang. Prescription: Modified Fengzao Meihe Tang (Wind-Drying Globus Hystericus Decoction). Ingredients: 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts prepared aconite root (added first), 10 parts angelica root, 5 parts raw ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 30 parts fragrant tea vegetable, and 10 parts stir-fried immature bitter orange peel. 7 doses to be decocted in water and taken warm after breakfast and dinner. 7 doses of Fengzao Meihe Tang were prescribed.

[0132] Typical Case 19

[0133] Ms. Chen, female, 59 years old. First visit on July 8, 2022. Chief complaint: throat obstruction and discomfort. Present illness: epigastric fullness, upward rushing of qi to the chest, bitter taste in the mouth, dry mouth, throat obstruction as if obstructed by phlegm, loose stools, pale red tongue with thin white coating, thready, wiry, and slippery pulse. Western medicine diagnosis: 1. Pharyngeal neurosis. 2. Chronic atrophic gastritis. Traditional Chinese medicine diagnosis: 1. Globus hystericus 2. Stomach fullness syndrome. Differentiation of syndromes: Upper heat and lower cold syndrome. Treatment principle: Clear the upper and warm the lower, harmonize yin and yang. Prescription: Modified Fengzao Meihe Tang (Wind-drying Globus Hystericus Decoction). Ingredients: 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts prepared aconite root (added first), 10 parts angelica root, 5 parts raw ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 30 parts fragrant tea vegetable, 10 parts stir-fried immature bitter orange peel. Seven doses were decocted in water and taken warm after breakfast and dinner. Second visit: All symptoms improved.

[0134] Typical Case 20

[0135] Mr. Tu, male, 44 years old. First visit on January 8, 2022. Chief complaint: throat obstruction and difficulty swallowing. Present illness: frequent feeling of something blocking the throat, shortness of breath rising to the chest, accompanied by epigastric fullness, mild intestinal metaplasia, alternating constipation and loose stools, pale red tongue with thin white coating, thready, wiry, and slippery pulse. Western medicine diagnosis: 1. Pharyngeal neurosis, 2. Chronic atrophic gastritis. Traditional Chinese medicine diagnosis: 1. Globus hystericus, 2. Stomach fullness. Syndrome differentiation: Upper heat and lower cold syndrome. Treatment principle: Clear the upper and warm the lower, harmonize yin and yang. Prescription: Modified Fengzao Meihe Tang (Wind-drying Globus Hystericus Decoction). Ingredients: 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts prepared aconite root (added first), 10 parts angelica root, 5 parts raw ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 30 parts fragrant tea vegetable, 10 parts stir-fried immature bitter orange peel. Seven doses were decocted in water and taken warm after breakfast and dinner. Second visit: All symptoms improved.

[0136] Those skilled in the art should understand that the embodiments of the present invention described above are merely examples and do not limit the present invention. The objectives of the present invention have been fully and effectively achieved. The functions and structural principles of the present invention have been shown and explained in the embodiments, and any modifications or variations of the embodiments of the present invention may be made without departing from the described principles.

Claims

1. A traditional Chinese medicine composition for treating globus hystericus, characterized in that, It is made from the following ingredients in parts by weight: 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts lightly ground aconite root, 10 parts angelica root, 5 parts sun-dried ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 30 parts fragrant tea vegetable, and 10 parts stir-fried immature bitter orange peel.

2. A traditional Chinese medicine composition for treating globus hystericus, characterized in that, It is made from the following ingredients in parts by weight: 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts lightly ground aconite root, 10 parts angelica root, 5 parts sun-dried ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 10 parts stir-fried immature bitter orange peel, 15 parts lily bulb, and 12 parts cypress seed.

3. A traditional Chinese medicine composition for treating globus hystericus, characterized in that, It is made from the following ingredients in parts by weight: 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts lightly ground aconite root, 10 parts angelica root, 5 parts sun-dried ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 15 parts stir-fried immature bitter orange peel, and 20 parts clematis root.

4. A traditional Chinese medicine composition for treating globus hystericus, characterized in that, It is made from the following ingredients in parts by weight: 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts lightly ground aconite root, 10 parts angelica root, 5 parts sun-dried ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 6 parts platycodon root, and 10 parts saposhnikovia root.

5. A traditional Chinese medicine composition for treating globus hystericus, characterized in that, It is made from the following ingredients in parts by weight: 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts lightly ground aconite root, 10 parts angelica root, 5 parts sun-dried ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 15 parts lily bulb, 20 parts fragrant tea vegetable, and 15 parts stir-fried immature bitter orange peel.

6. A traditional Chinese medicine composition for treating globus hystericus, characterized in that, It is made from the following ingredients in parts by weight: 20 parts dried plum, 3 parts asarum, 6 parts cinnamon twig, 10 parts lightly ground aconite root, 10 parts angelica root, 5 parts sun-dried ginseng, 10 parts phellodendron bark, 5 parts coptis root, 15 parts scrophularia root, 15 parts angelica root, 20 parts vitex fruit, 10 parts saposhnikovia root, and 12 parts stir-fried immature bitter orange peel.

7. The method for preparing the traditional Chinese medicine composition for treating globus hystericus according to any one of claims 1 to 6, characterized in that, Includes the following steps: (A) Soaking: Submerge all the raw materials described above in clean water and soak for at least 0.5 hours; (B) Decoction: After soaking, decoct twice. After the first decoction, pour out the decoction, add water and continue to decoct a second time, and retain the decoction from both decoctions. (C) Mixing: Mix the decoctions from the two decoctions thoroughly; (D) Remove residue and collect juice, then divide into doses and package. In the above steps, the decoction time should be controlled at 20-40 minutes each time. During the decoction process, the liquid should be brought to a boil. After reducing the liquid, the total amount of liquid should be controlled within the range of 200-300mL for the patient to take.