A broad-spectrum preservative for cosmetics and preparation method thereof

Abstract

The invention discloses a broad-spectrum preservative for cosmetics and a preparation method thereof, wherein the broad-spectrum preservative comprises the following raw materials in parts by mass: 30-50 parts of water, 10-15 parts of lactic acid and lactate, 10-15 parts of benzyl alcohol, 10-15 parts of costus root extract, 10-15 parts of forsythia extract, 10-15 parts of bamboo leaf prickly ash fruit extract, and 5-8 parts of natural antioxidants. The present invention adds antioxidants to the raw materials on the basis of adding a variety of natural antibacterial compositions to achieve a broad-spectrum antibacterial effect, and cooperates with the non-volatile property of lactic acid to help improve the thermal stability of the preservative, improves the problem of poor sterilization effect of natural preservatives on the market under high temperature environments, and the raw materials of the present invention are 100% extracted from pure natural animals and plants, do not contain toxic or irritating substances, are particularly suitable for skin cosmetics, and users have a better experience.

Description

Technical Field

[0001] The present invention relates to a preparation technology of a cosmetic preservative, in particular to a broad-spectrum cosmetic preservative and a preparation method thereof. Background Art

[0002] Preservatives are an important additive in the preparation of cosmetics, which can effectively prevent product changes and contamination caused by microorganisms during formulation, transportation, storage or consumer use. Preservatives play a very important role in water-containing products: they kill microorganisms and waterborne bacteria and prevent the growth of bacteria, molds and yeasts.

[0003] At present, the most frequently used preservatives in cosmetics are those derived from chemical synthesis. Common preservatives derived from chemical synthesis mainly include formaldehyde release systems, parabens, isothiazolinones, halogens, etc. Although preservatives derived from chemical synthesis can play a preservative role, effectively kill microorganisms and aquatic bacteria, and prevent fungal growth, they may irritate the skin, causing symptoms such as redness, swelling, and itching. People with sensitive skin are more likely to have such reactions. If cosmetics containing certain chemical synthesis preservatives are used for a long time, it may cause chronic inflammation, resulting in loss of skin elasticity and wrinkles. On the other hand, chemical preservatives kill all microorganisms on the surface of the skin without distinguishing between harmful and beneficial ones, which destroys the ecological balance of the microecological community and leads to the occurrence of skin diseases.

[0004] For the above reasons, some universities and enterprises have begun to develop and produce preservatives of natural origin: substances extracted from natural plants or animals with preservative effects, which are used to prevent the growth of microorganisms in cosmetics, thereby extending the shelf life of cosmetics. Compared with chemical synthetic preservatives, natural preservatives have many advantages: first, they are derived from natural substances, so they are gentler on the skin and will not cause allergies or irritation. Secondly, natural preservatives usually have moisturizing, antioxidant and anti-inflammatory effects, which can help maintain skin health. In addition, because their molecular structure is relatively simple, they are more easily absorbed by the skin, so they also have a better moisturizing effect.

[0005] Although pure natural preservatives have many advantages over chemical synthetic preservatives as mentioned above, they also have the problem of narrow antibacterial spectrum and poor bactericidal effect, especially in a high temperature environment. Summary of the invention

[0006] In view of the shortcomings of the prior art, the present invention aims to provide a broad-spectrum preservative for cosmetics to solve the problems of the narrow antibacterial spectrum of pure natural preservatives in the prior art and poor sterilization effect under high temperature environment. The specific technical scheme is as follows:

[0007] A broad-spectrum preservative for cosmetics, characterized by comprising the following raw materials in parts by mass: 30-50 parts of water, 10-15 parts of lactic acid and lactate, 10-15 parts of benzyl alcohol, 10-15 parts of costusroot extract, 10-15 parts of forsythia extract, 10-15 parts of Zanthoxylum bungeanum fruit extract, and 5-8 parts of natural antioxidants.

[0008] As a preferred embodiment: the raw materials include the following parts by mass: 45 parts of water, 12 parts of lactic acid and lactate, 12 parts of benzyl alcohol, 10 parts of costusroot extract, 15 parts of forsythia extract, 10 parts of Zanthoxylum bungeanum fruit extract, and 5 parts of natural antioxidants.

[0009] By selecting raw materials with appropriate mass fractions, a balance between the antibacterial effect and stability of the preservative is achieved, and the samples are made of pure natural raw materials, which are not easy to cause irritation to human skin.

[0010] As a preferred embodiment: the following raw materials are also included in parts by weight: 5-10 parts of tea polyphenols and 5-10 parts of patchouli.

[0011] By adding tea polyphenols and patchouli to the raw materials, tea polyphenols have bactericidal, antibacterial and antioxidant effects, increase the antibacterial spectrum of preservatives, and improve the stability of preservatives;

[0012] Patchouli has the effects of clearing heat, sterilization and anti-oxidation. When used in combination with tea polyphenols, it can improve the stability of preservatives. At the same time, its refreshing fragrance can also enhance the user experience of cosmetics.

[0013] As a preferred embodiment: the antioxidant is one or more of vitamin E, glutathione, astaxanthin, coenzyme Q10 and carotenoids.

[0014] Pure natural antioxidants such as vitamin E, glutathione, astaxanthin, coenzyme Q10 and carotenoids are selected. They have good antioxidant function, are not likely to cause overreaction when in contact with human skin, and have good compatibility with other raw materials.

[0015] As a preferred embodiment: the benzyl alcohol is extracted from one or more essential oils of jasmine, hyacinth, ylang-ylang, and bitter almond.

[0016] The benzyl alcohol in the present invention is benzyl alcohol extracted from natural plant essential oils, has no irritating odor, is relatively mild to the skin, and can destroy the cell membrane barrier by dissolving lipids, enhance the permeability of microbial cells to other antibacterial drugs, and inhibit the necessary enzymes involved in the Krebs cycle.

[0017] As a preferred embodiment: the Forsythia suspensa extract is extracted from Forsythia suspensa.

[0018] Forsythia has a broad-spectrum antibacterial and antiviral effect, which mainly depends on the forsythiaside contained in Forsythia. The forsythiaside content in green Forsythia is 0.078%, while that in old Forsythia is only 0.013%. The forsythiaside content in green Forsythia is higher than that in old Forsythia, and the forsythiaside in green Forsythia mainly comes from the fruit shell, which is easy to extract.

[0019] The present invention also provides a method for preparing a broad-spectrum preservative for cosmetics, comprising the following steps:

[0020] S1: preparing raw materials: fermenting at least one of corn and sugar cane, separating and purifying lactic acid by distillation after fermentation, and mixing it with lactate;

[0021] Extracting natural benzyl alcohol from one or more essential oils of jasmine, hyacinth, ylang-ylang, and bitter almond by extraction;

[0022] Prepare costus root extract, forsythia suspensa extract, Zanthoxylum bungeanum fruit extract, distilled water and antioxidants;

[0023] S2: Processing the extract: 10-15 parts of costusroot extract, 10-15 parts of forsythia extract, and 10-15 parts of zanthoxylum bungeanum fruit extract are mixed, and the mixed extract is crushed by a grinder, and then sieved, and the sieved residue is put into the grinder again for crushing or manually grinding, and then sieved, and the above process is repeated until no residue can be sieved out to obtain the extract powder for standby use;

[0024] S3: preparing a mixed solution: preparing 30-50 parts of distilled water, taking 10-15 parts of lactic acid and lactate, 10-15 parts of benzyl alcohol and no more than half of distilled water and mixing, and then adding 5-8 parts of antioxidant, stirring, standing and precipitating to form a layered mixed solution, and setting aside;

[0025] S4: Adding the extract: Add the extract powder obtained in step S2 to the layered mixed solution formed in step S3, and heat to 35°C-37°C, stir, and let stand to precipitate, then add distilled water in an amount not exceeding 1 part by mass each time, stir, and let stand to precipitate, and repeat the above steps until all the raw materials are dissolved in the mixed solution to obtain a heated solution;

[0026] S5: Obtaining a finished solution: Cooling the heated solution obtained in step S4 to 20°C-25°C, stirring, standing and settling, and then filtering the precipitate to obtain a finished preservative solution.

[0027] In the present invention, in the process of preparing the broad-spectrum preservative for cosmetics, when preparing the mixture, no excessive water is added, so that the raw materials in the mixed solution cannot be completely dissolved in the water, and then the temperature is increased and distilled water is continuously added until the precipitate is completely dissolved, so as to ensure that the mixed solution reaches a fully dissolved state under the increased temperature. In the normal increased temperature state, the liquid dissolution rate will be high, and after cooling to room temperature again, part of the precipitate will be precipitated. After removing the precipitated precipitate, the remaining solution is the solution with the highest concentration under room temperature. Therefore, in addition to having the effect of broad-spectrum antibacterial, it is not easy to dissolve into other substances and has high stability. At the same time, due to the addition of antioxidants and stabilizers, it can maintain a certain antiseptic function under high temperature environment, and will not dilute the concentration of the cosmetics after mixing with the cosmetics, thereby affecting the efficacy.

[0028] As a preferred embodiment: the precipitate filtered in step S5 is collected and sealed for storage, and used in the next step S4 of preparing the preservative: the extract powder obtained in step S2 is added to the layered mixed liquid formed in step S3, and then the precipitate is added.

[0029] The composition of the precipitate filtered out in step 5 is consistent with that of the finished preservative, so it can be collected and added back into the layered mixed liquid, and then dissolved in water, which can effectively save costs and improve the production efficiency of the preservative.

[0030] As a preferred embodiment: in step S2, the obtained extract powder is sealed and refrigerated in an environment of 0°C-5°C.

[0031] Setting a low temperature environment of 0℃-5℃ to store the extract powder is beneficial to ensure the activity of the extract powder. On the other hand, it also appropriately lowers the temperature. When the extract powder comes into contact with the mixed liquid, the temperature of the mixed liquid is lowered due to the low temperature of the extract powder. Since a lot of stirring and a long time of standing are required at the beginning of mixing, the lower temperature can reduce volatilization and save costs on the one hand. On the other hand, a large amount of distilled water must be added at the beginning of mixing. In a low temperature environment, the precipitation caused by adding water and stirring is more obvious, which avoids excessive water injection at one time, which affects the product concentration and efficacy.

[0032] The present invention also provides application of the broad-spectrum preservative for cosmetics in skin cosmetics.

[0033] Since the raw materials of the present invention are all extracted from pure nature, do not contain irritating substances and odors, and a variety of Chinese herbal medicines with odors are added thereto, they are particularly suitable for use as preservatives in cosmetics that come into contact with the skin. In addition, the product has good thermal stability and a large pH adaptability, and can also have good antiseptic performance in an environment where the pH value on the skin surface is neutral and the temperature is slightly high.

[0034] Compared with the prior art, the present invention has the following beneficial effects:

[0035] The present invention adds lactic acid and lactate into the raw materials. Lactic acid and lactate are obtained by fermentation of natural plants and are natural components of human skin and hair. They have unique pH adjustment and moisturizing functions, have bactericidal effects, are non-irritating to human skin, and lactic acid also has a certain stabilizer function.

[0036] The invention adds costus root extract to the raw materials. Costus root has antibacterial and anti-inflammatory effects, and utilizes its strong aromatic smell to be added to cosmetics to enhance user experience.

[0037] The present invention adds a Forsythia suspensa extract to the raw material, which has a broad-spectrum antibacterial effect, contains rich vitamin C, has an antioxidant function, and improves the stability of the preservative;

[0038] On the basis of the broad-spectrum antibacterial effect of the present invention, an antioxidant is added to the raw material, and the non-volatile property of lactic acid is combined to help improve the thermal stability of the preservative, thereby improving the problem that the sterilization effect of natural preservatives currently on the market deteriorates under high temperature environments;

[0039] The present invention uses 100% pure natural raw materials, especially benzyl alcohol raw materials are extracted from essential oils of natural plants. According to the international standard ISO 16128, the natural origin index of the preservative is as high as 100%;

[0040] Compared with chemical synthetic preservatives that kill all bacteria, the MIC value (minimum inhibitory concentration) of the present invention when acting on pathogens on the skin surface is lower than the MIC value when acting on certain commensal bacteria (such as Staphylococcus epidermidis and Corynebacterium striatum). Therefore, at the concentration used, pathogenic bacteria can be selectively killed without killing beneficial bacteria, thereby protecting the balance of the microbial community on the skin surface.

[0041] The preservative preparation method of the present invention has a more environmentally friendly process, reducing waste and energy consumption;

[0042] The preservative of the present invention is low-irritating to human skin, colorless, mild odor, 100% water-soluble and free of parabens, formaldehyde donors and halogens.

[0043] It performs well in both wash-free and rinse-off cosmetics, providing economical and efficient antiseptic protection while also reducing the irritation that may be caused by the high usage of traditional preservatives.

[0044] Among the components of the preservative disclosed in the present invention, lactic acid and lactate have the function of skin care and moisturizing, are components of the skin's natural moisturizing factor, and have the antibacterial property of organic acid. When used in combination with benzyl alcohol, they can still have good antibacterial ability in a neutral or even weakly alkaline environment, are effective at pH values ​​of 4-8, have a broad-spectrum preservative effect (mainly against bacteria, yeast, and mold), and overcome the disadvantage that general preservatives need to be in a strongly acidic environment to exert their antibacterial effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0045] Figure 1 The present invention is a flow chart of a method for preparing a broad-spectrum preservative for cosmetics disclosed in the present invention. DETAILED DESCRIPTION

[0046] The embodiments of the present disclosure are described in detail below with reference to the accompanying drawings.

[0047] The following describes the embodiments of the present disclosure through specific examples, and those skilled in the art can easily understand other advantages and effects of the present disclosure from the contents disclosed in this specification. Obviously, the described embodiments are only a part of the embodiments of the present disclosure, rather than all of the embodiments. The present disclosure can also be implemented or applied through other different specific embodiments, and the details in this specification can also be modified or changed in various ways based on different viewpoints and applications without departing from the spirit of the present disclosure. It should be noted that the following embodiments and features in the embodiments can be combined with each other without conflict. Based on the embodiments in the present disclosure, all other embodiments obtained by ordinary technicians in the field without making creative work are within the scope of protection of the present disclosure.

[0048] A broad-spectrum preservative for cosmetics comprises the following raw materials in parts by mass: 30-50 parts of water, 10-15 parts of lactic acid and lactate, 10-15 parts of benzyl alcohol, 10-15 parts of costusroot extract, 10-15 parts of forsythia extract, 10-15 parts of Zanthoxylum bungeanum fruit extract, and 5-8 parts of natural antioxidants.

[0049] Among them, lactic acid and lactate are derived from corn and sugar cane, and are obtained by fermenting muscle glycogen. They are natural components of human skin and hair, have unique pH adjustment and moisturizing functions, and are widely used in a variety of daily chemical products, such as bath products, skin care products, hair care products, and oral care products.

[0050] Naturally extracted benzyl alcohol: It is an aromatic alcohol with a mild sweet taste, mainly derived from the essential oil components of some plant flowers and fruits, such as jasmine, hyacinth, ylang-ylang, and natural components of many edible fruits and green / black tea. It is mainly used as a preservative and fragrance in cosmetics, food and medicine, and can also be used as a local anesthetic. Benzyl alcohol mainly fights bacteria and molds. The mechanism of action is to destroy the cell membrane barrier through the dissolution of lipids, enhance the permeability of microbial cells to other antimicrobial drugs, and inhibit the necessary enzymes involved in the Krebs cycle. It is approved for global use, mainly in combination with other preservatives, and can replace highly effective and controversial preservatives.

[0051] The extract of Aucklearia Lappa is rich in volatile oil, one of the main components of which is anisaldehyde, which has pharmacological effects such as antibacterial, anti-inflammatory, and digestion-promoting, and can be used to make medicines or drug formulas.

[0052] Forsythia Suspensa Extract: Forsythia Suspensa contains triterpenoid saponins, and the peel contains sterols, phenolic components (forsythia phenol), alkaloids, saponins, oleanolic acid, coumarins, and rich vitamins and a small amount of volatile oils. Forsythia Suspensa has a broad-spectrum antibacterial effect, and has a strong inhibitory effect on Staphylococcus aureus and Shigella dysenteriae. It has an inhibitory effect on Salmonella typhi, Vibrio cholerae, Escherichia coli, Pseudomonas aeruginosa, Bordetella pertussis, Mycobacterium tuberculosis, Pneumococcus, and hemolytic Streptococcus. It also has an inhibitory effect on influenza virus and has antifungal effects. Alcohol extract has a killing effect on Leptospira. Forsythia phenol is an effective antibacterial ingredient. The oleanolic acid contained in this product has cardiotonic, diuretic and blood pressure lowering effects; Forsythia Suspensa also contains rich vitamin C, which can reduce vascular permeability and fragility and prevent bleeding. The decoction has an antiemetic effect and can counteract vomiting caused by digitalis and apomorphine. The antiemetic effect may be due to the fact that Forsythia can inhibit the emetic chemoreceptor area of ​​the medulla oblongata. Oleanolic acid is the effective component of Forsythia against liver damage, and both can reduce serum alanine aminotransferase in experimental liver damage animals. The content of forsythia glycoside in green Forsythia is 0.078%, while that in old Forsythia is only 0.013%. The content of forsythia glycoside in green Forsythia is higher than that in old Forsythia, and the forsythia glycoside in green Forsythia mainly comes from the fruit shell, which is easy to extract. Therefore, in the present invention, it is preferred to use green Forsythia extract to prepare the preservative solution.

[0053] Zanthoxylum alata fruit extract. Zanthoxylum alata contains a lot of volatile plant oils, especially limonene, which has strong bactericidal and antibacterial effects. The roots, stems, leaves, fruits and seeds are all used as herbal medicines. It can dispel wind and cold, promote qi circulation and relieve pain. It can treat rheumatoid arthritis, toothache, and swelling and pain caused by falls. It is also used as an anthelmintic and fish intoxicant.

[0054] The antioxidant in the present invention is preferably one or more of vitamin E, glutathione, astaxanthin, coenzyme Q10 and carotenoids. In the preferred embodiment of the present invention, the raw materials also include: 5-10 parts of tea polyphenols and 5-10 parts of patchouli. Tea polyphenols have bactericidal, antibacterial and antioxidant effects, can effectively inhibit Coriolus versicolor and Glechoma spp., increase the antibacterial spectrum of preservatives, and improve the stability of preservatives; patchouli has the effects of clearing heat, sterilization and antioxidant. When used in combination with tea polyphenols to improve the stability of preservatives, its fresh fragrance can also increase the use experience of cosmetics. The non-volatile property of lactic acid is used in combination with patchouli as a volatile oil, and it will not affect the efficacy of preservatives while emitting fragrance.

[0055] Embodiment 1

[0056] The preservative disclosed in the present invention has good thermal stability and low volatility due to the use of lactic acid and benzyl alcohol as raw materials, and can maintain good antibacterial function in acidic and weakly alkaline environments:

[0057] Using hand sanitizer as a nutrient carrier, 1% of the preservative composition of the present invention was added to the formula, specifically: 45 parts of water, 12 parts of lactic acid and lactate, 12 parts of benzyl alcohol, 10 parts of costusroot extract, 15 parts of forsythia extract, 10 parts of bamboo leaf prickly ash fruit extract, and 5 parts of astaxanthin, and the preservative effect was tested for 28 days.

[0058] Specifically:

[0059]

[0060] Hand sanitizer preparation process:

[0061] (1) Mix phase A, keep stirring at 400 rpm, disperse evenly, and heat to 85°C for later use;

[0062] (2) Add phase B to phase A, stir at 400 rpm until dissolved, and heat to 85°C for later use;

[0063] (3) Cool down to 45°C and add the components in phase C in sequence;

[0064] The pH (10% aqueous solution) of hand sanitizer 1 was controlled at 5.0-6.0, and the pH (10% aqueous solution) of hand sanitizer 2 was controlled at 7.0-8.0.

[0065] Inspection methods and standards:

[0066] United States Pharmacopoeia USP51, European Pharmacopoeia EP9.0-5.1.3

[0067] USP51: Compared with the initial value, the value did not increase on days 14 and 28;

[0068] EP9.0-5.1.3: The logarithmic reduction of fungi on the 14th day is not less than 1 compared to the initial value, and the values ​​from the 14th day to the 28th day do not increase;

[0069] Tested microorganisms:

[0070] Escherichia Coli ATCC8739

[0071] Staphylococcus Aureus ATCC6538

[0072] Pseudomonas Aeruginosa ATCC9027

[0073] Candida Albicans ATCC10231

[0074] Aspergillus Niger ATCC16404

[0075] Experimental results:

[0076]

[0077] Conclusion: The composition can pass two bacterial and fungal challenges and has excellent antiseptic effect. In an acidic and weakly alkaline environment of pH 7-8, the preservative of the present invention has better antiseptic and antibacterial effects.

[0078] Embodiment 2

[0079] The hand sanitizer in Example 1 is still used as a carrier, and 1% of the preservative solution is added. The first control group is the preservative formula in Example 1, the second control group replaces lactic acid and lactate with sorbic acid and sorbate, the third control group adds 8 parts of tea polyphenols, the fourth control group adds 8 parts of patchouli, and the fifth control group adds 8 parts of tea polyphenols and 8 parts of patchouli. The test environment is ph = 5-6, the temperature is 40°C, and the USP51 standard is adopted. The experimental results are as follows:

[0080] The first control group: the logarithmic value on day 14 was <1.3, the logarithmic reduction value was >5.2, the bacteria did not increase from day 14 to day 28, and the fungi did not increase from day 14 to day 28;

[0081] The second control group: the logarithmic value on day 14 was <1.5, the logarithmic reduction value was >5.0, the bacteria did not increase from day 14 to day 28, and the fungi did not increase from day 14 to day 28;

[0082] The third control group: the logarithmic value on day 14 was <1.1, the logarithmic reduction value was >5.4, the bacteria did not increase from day 14 to day 28, and the fungi did not increase from day 14 to day 28;

[0083] The fourth control group: the logarithmic value on day 14 was <1.3, the logarithmic reduction value was >5.2, the bacteria did not increase from day 14 to day 28, and the fungi did not increase from day 14 to day 28;

[0084] The fifth control group: the logarithmic value on day 14 was <1.0, the logarithmic reduction value was >5.5, the bacteria did not increase from day 14 to day 28, and the fungi did not increase from day 14 to day 28.

[0085] It can be concluded that in a weakly acidic environment with a pH of 5-6 and a temperature of 40°C, which is higher than normal temperature, the preservative function of lactic acid is higher than that of sorbic acid, the addition of tea polyphenols can effectively improve the stability of the preservative, and the addition of patchouli has no obvious change. The addition of a mixture of tea polyphenols and patchouli can better ensure the antibacterial effect of the preservative and ensure the stability and efficacy of the preservative in a high temperature environment.

[0086] Embodiment 3

[0087] One of the preferred preparation methods of the broad-spectrum preservative for cosmetics disclosed in the present invention is as follows Figure 1 As shown:

[0088] S1: preparing raw materials: fermenting sugar cane, separating and purifying lactic acid by distillation after fermentation, and mixing it with lactate;

[0089] Natural benzyl alcohol is extracted from the essential oils of hyacinth and ylang-ylang flowers;

[0090] Prepare costus root extract, forsythia suspensa extract, Zanthoxylum bungeanum fruit extract, distilled water and anti-astaxanthin;

[0091] S2: Processing the extract: 10 parts of costusroot extract, 15 parts of forsythia extract, 10 parts of Zanthoxylum bungeanum fruit extract, and 5 parts of patchouli are mixed, and the mixed extract is crushed by a grinder, sieved after crushing, and the sieved residue is put into the grinder again for crushing or manually ground, and then sieved, and the above process is repeated until no residue can be sieved out to obtain the extract powder, and 8 parts of tea polyphenols powder are mixed for standby use;

[0092] S3: preparing a mixed solution: preparing 50 parts of distilled water, taking 12 parts of lactic acid and lactate, 12 parts of benzyl alcohol and 15 parts of distilled water and mixing them, and then adding 5 parts of antioxidant, stirring, standing and precipitating to form a layered mixed solution, and setting aside;

[0093] S4: Adding the extract: Add the extract powder obtained in step S2 to the layered mixed solution formed in step S3, and heat to 35°C-37°C, stir, and let stand to precipitate, then add distilled water in an amount not exceeding 1 part by mass each time, stir, and let stand to precipitate, and repeat the above steps until all the raw materials are dissolved in the mixed solution to obtain a heated solution;

[0094] S5: Obtaining a finished solution: Cooling the heated solution obtained in step S4 to 20°C-25°C, stirring, standing and settling, and then filtering the precipitate to obtain a finished preservative solution.

[0095] The hand washing liquid in Example 1 is still used as a carrier, and 1% of the preservative solution is added, the pH value is 5-6, and the temperature is 40°C.

[0096] The first control group used the preservative solution prepared as above;

[0097] In the second control group, 50 parts of distilled water were directly added in step S3, and then mixed with the extract powder and stirred to obtain a preservative solution;

[0098] In the third control group, the heating step was omitted in step S4, and distilled water was directly added in an amount not exceeding 1 portion each time, stirred, and allowed to stand for precipitation. The above steps were repeated until all the raw materials were dissolved in the mixed solution to obtain a preservative solution.

[0099] Using USP51, the test results are as follows:

[0100] The first control group: the logarithmic value on day 14 was <1.1, the logarithmic reduction value was >5.4, the bacteria did not increase from day 14 to day 28, and the fungi did not increase from day 14 to day 28;

[0101] The second control group: the logarithmic value on day 14 was <1.4, the logarithmic reduction value was >5.1, the bacteria did not increase from day 14 to day 28, and the fungi did not increase from day 14 to day 28;

[0102] The third control group: the logarithmic value on day 14 was <1.3, the logarithmic reduction value was >5.2, the bacteria did not increase from day 14 to day 28, and the fungi did not increase from day 14 to day 28.

[0103] It is concluded that the antibacterial effect of the preservative of the present invention is related to the concentration of the preservative when the temperature is higher than room temperature. When the preservative has just reached a fully dissolved state, its concentration is the highest and no other substances can be dissolved therein. Its stability is also higher and it can remain active in an environment of 40°C and maintain a better antibacterial effect.

[0104] Embodiment 4

[0105] In order to test the irritation of the preservative solvent of the present invention to human skin, the following experiment was carried out:

[0106] The hand washing liquid in Example 1 is still used as a carrier, and 4% of the preservative solution is added to make the effect difference more obvious;

[0107] The first control group: using the preservative solution of the first control group in Example 3;

[0108] The second control group: using common paraben preservatives on the market;

[0109] The third control group: the benzyl alcohol in the raw material was replaced with the benzyl alcohol obtained by hydrolysis of benzyl chloride in the same mass fraction;

[0110] The fourth control group: no tea polyphenols and patchouli were added;

[0111] The fifth control group: lactic acid and lactate were replaced by sorbic acid and sorbate.

[0112] Two groups of test people were selected. The first test group was children aged 8-14 years old, and the second test group was adults aged 18 years old or above. There were 100 people in each group. They were respectively washed with the hand sanitizers of the five control groups above at intervals of half an hour. The evaluation of the hand sanitizers in each control group was recorded. The experimental results are as follows:

[0113]

[0114] It is concluded that the preservatives prepared with the natural raw materials and preparation method of the present invention are significantly less irritating than the common paraben preservatives on the market, especially the pure naturally extracted lactic acid and lactate and benzyl alcohol are extremely less irritating to the human body, and the added tea polyphenols and patchouli have little effect on irritation, but can produce a refreshing direction and improve the user experience.

[0115] In the present invention, unless otherwise clearly specified and limited, the first feature "on" the second feature may be that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. "Multiple" means at least two, such as two, three, etc., unless otherwise clearly and specifically limited.

[0116] The above is only for explaining the implementation mode of the present invention and is not intended to limit the present invention. For those skilled in the art, any modification, equivalent substitution, improvement, etc. made within the spirit and principle of the present invention without creative work should be included in the protection scope of the present invention.

Claims

1. A broad-spectrum preservative for cosmetics, characterized in that: The invention comprises the following raw materials in parts by weight: 30-50 parts of water, 10-15 parts of lactic acid and lactate, 10-15 parts of benzyl alcohol, 10-15 parts of costusroot extract, 10-15 parts of forsythia extract, 10-15 parts of zanthoxylum bungeanum fruit extract, 5-8 parts of natural antioxidants, 5-10 parts of tea polyphenols and 5-10 parts of patchouli.

2. The broad-spectrum preservative for cosmetics according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 45 parts of water, 12 parts of lactic acid and lactate, 12 parts of benzyl alcohol, 10 parts of costusroot extract, 15 parts of forsythia extract, 10 parts of Zanthoxylum bungeanum fruit extract and 5 parts of natural antioxidant.

3. The broad-spectrum preservative for cosmetics according to claim 1, characterized in that :The antioxidant is one or more of vitamin E, glutathione, astaxanthin, coenzyme Q10 and carotenoids.

4. The broad-spectrum preservative for cosmetics according to claim 1, characterized in that: The benzyl alcohol is extracted from one or more essential oils of jasmine, hyacinth, ylang-ylang and bitter almond.

5. The broad-spectrum preservative for cosmetics according to claim 1, characterized in that: The Forsythia suspensa extract is extracted from Forsythia suspensa.

6. A method for preparing a broad-spectrum preservative for cosmetics, characterized in that: The following steps are involved: S1: preparing raw materials: fermenting at least one of corn and sugar cane, separating and purifying lactic acid by distillation after fermentation, and mixing it with lactate; Extracting natural benzyl alcohol from one or more essential oils of jasmine, hyacinth, ylang-ylang, and bitter almond by extraction; Prepare costus root extract, forsythia suspensa extract, Zanthoxylum bungeanum fruit extract, distilled water and antioxidants; S2: Processing the extract: 10-15 parts of costusroot extract, 10-15 parts of forsythia extract, and 10-15 parts of zanthoxylum bungeanum fruit extract are mixed, and the mixed extract is crushed by a grinder, and then sieved, and the sieved residue is put into the grinder again for crushing or manually grinding, and then sieved, and the above process is repeated until no residue can be sieved out to obtain the extract powder for standby use; S3: preparing a mixed solution: preparing 30-50 parts of distilled water, taking 10-15 parts of lactic acid and lactate, 10-15 parts of benzyl alcohol and no more than half of distilled water and mixing, and then adding 5-8 parts of antioxidant, stirring, standing and precipitating to form a layered mixed solution, and setting aside; S4: Adding the extract: Add the extract powder obtained in step S2 to the layered mixed solution formed in step S3, and heat to 35°C-37°C, stir, and let stand to precipitate, then add distilled water in an amount not exceeding 1 part by mass each time, stir, and let stand to precipitate, and repeat the above steps until all the raw materials are dissolved in the mixed solution to obtain a heated solution; S5: Obtaining a finished product solution: Cooling the heated solution obtained in step S4 to 20°C-25°C, stirring, standing and settling, and then filtering the precipitate to obtain a finished preservative solution; The precipitate filtered in step S5 is collected and sealed for storage, and used in the next step S4 of preparing the preservative: the extract powder obtained in step S2 is added to the layered mixed solution formed in step S3, and then the precipitate is added; In step S2, the obtained extract powder is sealed and refrigerated in an environment of 0°C-5°C.

7. Use of the broad-spectrum preservative for cosmetics according to any one of claims 1 to 5 in the preparation of skin cosmetics.

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