A traditional Chinese medicine preparation for treating diaper dermatitis and a preparation method thereof

Abstract

This invention relates to the field of traditional Chinese medicine (TCM) technology, providing a TCM preparation for treating diaper dermatitis and its preparation method. The TCM preparation for treating diaper dermatitis comprises the following components by weight: 5-10g of Phellodendron bark, 5-10g of Sophora flavescens root, 5-10g of Kochia scoparia fruit, 5-10g of Sanguisorba officinalis root, 5-10g of Platycladus orientalis leaf, 5-10g of Lycium chinense root bark, 5-10g of Pogostemon cablin, and 5-10g of Polygonatum sibiricum. The optimal weight proportion is: 10g each of Phellodendron bark, Sophora flavescens root, Kochia scoparia fruit, Sanguisorba officinalis root, Platycladus orientalis leaf, Lycium chinense root bark, Pogostemon cablin, and Polygonatum sibiricum. This TCM preparation for treating diaper dermatitis not only selects herbs with heat-clearing, dampness-drying, blood-cooling, and detoxifying effects, but also considers the delicate nature of children's internal organs and insufficient vital energy, selecting herbs such as Polygonatum sibiricum and Pogostemon cablin to achieve the purpose of tonifying deficiency to expel pathogens, addressing both the root cause and the symptoms.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine preparation for treating diaper dermatitis and a preparation method thereof. BACKGROUND

[0002] Diaper dermatitis (DD) is a common and frequently-occurring disease of children's skin, and its main clinical manifestations are large patches of red plaques, papules or exudation of erosion, even secondary bacterial or candida infection, occurring at diaper sites with clear boundaries. In severe cases, especially in malnourished infants with chronic diarrhea, skin ulcers can occur. According to statistics, the incidence of DD in children is 14.1% to 35.1% per year, which is prone to secondary fungal or bacterial infection, decreased immunity, etc., and endangers life. With the widespread use of disposable diapers in infants, the quality of disposable diapers is uneven, and pregnant women have high-calorie diets, which makes the incidence of the disease increase year by year. How to prevent and treat the disease is imminent.

[0003] Western medicine mainly uses local anti-inflammatory and astringent methods, and mainly uses zinc oxide preparations, tannic acid ointment, erythromycin ointment, calamine lotion, boric acid powder, or uses them alone or in combination, and also uses oxygen therapy and electromagnetic wave therapy, but the curative effects are not as good as those of traditional Chinese medicine treatment. Because of the particularity of the constitution of children, compared with western medicine, traditional Chinese medicine external washing has the characteristics of simplicity, safety and effectiveness in the treatment of diaper dermatitis. Traditional Chinese medicine believes that diaper dermatitis in children is extremely similar to the description of the disease in ancient medical books "Dan", "Jiuzi Sore", and "Monkey Malnutrition", which is a superficial skin inflammation occurring on the buttocks of children, mainly with skin moisture, papules, erythema, erosion and pain. Ancient and modern Chinese medicine doctors use the dialectical method of combining local and overall observation of skin lesions to observe different diseases to determine the dialectical type. It is believed that the disease is related to internal fire (fetal toxins), improper use of diapers, and the skin of the buttocks is affected by damp heat and dirty evil, internal and external damp heat and fire toxin, blood stasis, and the treatment is mainly external treatment, and different treatment methods such as clearing heat and blood, detoxifying and swelling, and removing corruption and promoting tissue regeneration are used to achieve the goal of treating the symptoms and the root cause simultaneously. SUMMARY

[0004] The present application aims to provide a traditional Chinese medicine preparation for treating diaper dermatitis and a preparation method thereof, which aims to solve the problems raised in the background art.

[0005] To achieve the above-mentioned purpose, the present application provides the following technical solutions:

[0006] A traditional Chinese medicine preparation for treating diaper dermatitis comprises the following components by weight: 5-10g of Huangbai, 5-10g of Kushen, 5-10g of Difushizi, 5-10g of Diyu, 5-10g of Cibaicai, 5-10g of Diguopi, 5-10g of Huoxiang, and 5-10g of Huangjing.

[0007] Further, the following components by weight are included: Phellodendri Chinensis Cortex 10g, Sophorae Flavescentis Radix 10g, Fructus Kochiae 10g, Radix Sanguisorbae 10g, Biota Orientalis Leaf 10g, Cortex Lycii Radicis 10g, Agastache Rugosus 10g, Polygonatum Sibiricum 10g.

[0008] Further, the following components by weight are included: Phellodendri Chinensis Cortex 7-9g, Sophorae Flavescentis Radix 7-9g, Fructus Kochiae 7-9g, Radix Sanguisorbae 7-9g, Biota Orientalis Leaf 7-9g, Cortex Lycii Radicis 7-9g, Agastache Rugosus 7-9g, Polygonatum Sibiricum 7-9g.

[0009] A preparation method of the traditional Chinese medicine preparation for treating diaper dermatitis according to the above description, comprising the following steps:

[0010] The components are weighed according to the prescription, soaked for 20-40 minutes, and then decocted until 500mL. After standing until the medicinal liquid and precipitate are layered, filtration recovery and juice taking are performed, and the medicinal liquid is bottled and divided into two parts for later use.

[0011] Compared with the prior art, the present application has the following beneficial effects:

[0012] The traditional Chinese medicine preparation for treating diaper dermatitis not only selects traditional Chinese medicines with heat-clearing and dampness-drying, blood-cooling and detoxification effects, but also considers the characteristics of tender viscera and insufficient vital qi of children, and selects traditional Chinese medicines such as Polygonatum Sibiricum and Agastache Rugosus to achieve the purpose of tonifying deficiency to expel evil, and to treat both symptoms and root causes. DETAILED DESCRIPTION

[0013] In order to make the purpose, technical scheme and advantages of the present application clearer, the present application is further described in detail below in combination with examples. It should be understood that the specific examples described herein are only used to explain the present application and do not limit the present application.

[0014] The specific implementation of the present application is described in detail below in combination with specific examples.

[0015] Example 1, one embodiment of the present application provides a traditional Chinese medicine preparation for treating diaper dermatitis, which includes the following components by weight: Phellodendri Chinensis Cortex 5-10g, Sophorae Flavescentis Radix 5-10g, Fructus Kochiae 5-10g, Radix Sanguisorbae 5-10g, Biota Orientalis Leaf 5-10g, Cortex Lycii Radicis 5-10g, Agastache Rugosus 5-10g, Polygonatum Sibiricum 5-10g.

[0016] The preparation method of the traditional Chinese medicine preparation, comprising the following steps:

[0017] The components are weighed according to the prescription, soaked for 20-40 minutes, and then decocted until about 500mL. After standing until the medicinal liquid and precipitate are layered, filtration recovery and juice taking are performed, and the medicinal liquid is bottled and divided into two parts for later use.

[0018] In the embodiment of the present application, preferably, according to the traditional Chinese medicine, diaper dermatitis in children is caused by internal fire (fetal toxin) and improper use of diapers, and the skin of the buttocks is affected by damp-heat and turbid evil, internal and external damp-heat and fire toxin, blood stasis, and the like. In the present application, Huangbai is used as the monarch drug for clearing heat and drying dampness, purging fire and detoxifying; Kuhsiang can clear heat and dry dampness, and kill insects and relieve itching; Dishizi can clear heat and dry dampness, dispel wind and relieve itching; Disui can cool blood, detoxify and astringe sores, and the above three drugs are used as the ministerial drugs; Cidai leaves are cold and cool into blood and dispel wind, and are combined with Diguopi to enhance the blood cooling effect of the present application; Huoxiang can resolve dampness and release the exterior, and regulate the spleen and stomach; Huangjing can tonify qi, nourish yin, invigorate the spleen, moisten the lung and strengthen the kidney, and is combined with Huoxiang to achieve the purpose of treating the root and the branch; the traditional Chinese medicine preparation has the effects of clearing heat and drying dampness, cooling blood and detoxifying, and nourishing yin and resolving rash, and can effectively treat diaper dermatitis in children. The curative effect is remarkable, and the adverse reactions are few.

[0019] According to the severity of diaper dermatitis in children, 10g of Marsdenia tenacissima, 10g of Lonicera japonica and 10g of Angelica sinensis can be added to the above-mentioned traditional Chinese medicine composition to further improve the symptoms.

[0020] In one embodiment of the present application, a traditional Chinese medicine preparation for treating diaper dermatitis is provided, which comprises the following components by weight: Huangbai 10g, Kuhsiang 10g, Dishizi 10g, Disui 10g, Cidai leaves 10g, Diguopi 10g, Huoxiang 10g and Huangjing 10g.

[0021] The preparation method of the traditional Chinese medicine preparation comprises the following steps:

[0022] According to the prescription amount, an appropriate amount of each component is weighed, soaked for 20-40min, and then decocted until about 500mL. After standing until the medicinal liquid and the precipitate are layered, the medicinal liquid is recovered, filtered, and bottled. Two portions are obtained, and are ready for use.

[0023] In one embodiment of the present application, a traditional Chinese medicine preparation for treating diaper dermatitis is provided, which comprises the following components by weight: Huangbai 10g, Kuhsiang 10g, Dishizi 10g, Disui 10g, Cidai leaves 10g, Diguopi 10g, Huoxiang 10g and Huangjing 10g.

[0024] The preparation method of the traditional Chinese medicine preparation comprises the following steps:

[0025] According to the prescription amount, an appropriate amount of each component is weighed, soaked for 20-40min, and then decocted until about 500mL. After standing until the medicinal liquid and the precipitate are layered, the medicinal liquid is recovered, filtered, and bottled. Two portions are obtained, and are ready for use.

[0026] The usage and dosage of the above-mentioned traditional Chinese medicine preparation are as follows: external washing, 1 time in the morning and 1 time in the evening. After preparation, take one portion of the medicinal liquid to 37℃, and use gauze to dip an appropriate amount of medicinal liquid to wash the affected area, without the need for rinsing with clean water. Another portion can be placed in cold storage, and when used, it is heated to 37℃, and used as before. If the child has a large area of dermatitis, the amount of water can be increased to 1500ml, and boiled to about 800ml, divided into two portions, and when used, the entire buttocks is soaked in the medicinal liquid, without the need for rinsing with clean water.

[0027] The following illustrates the therapeutic effect of the traditional Chinese medicine preparation through clinical observation (1 dose per day, 2 times a day, 7 days as a course of treatment).

[0028] Yuan, female, 7 months old. Diagnosed on November 5, 2022. The child had redness on the buttocks and perineum, crying, restlessness, poor appetite, poor sleep, yellow urine, normal stool, pale red tongue, yellow and greasy fur, and slippery pulse. Diagnosed as infantile diaper dermatitis. External washing of the traditional Chinese medicine preparation of Example 2 of the present application, 1 course of treatment, the child's redness on the buttocks and perineum was reduced, and the crying and eating improved. Continue external washing for 1 course of treatment, the child's redness on the buttocks and perineum subsided, and the appetite and sleep were normal. Follow-up after half a year showed no recurrence.

[0029] Zhou, female, 6 months old. Diagnosed on September 11, 2022. The child had papules on the buttocks with exudate, scratching, skin moisture, obvious crying, restlessness, poor appetite, refusal to eat, poor sleep, yellow urine, dry stool, pale red tongue, yellow and greasy fur, and slippery pulse. Diagnosed as infantile diaper dermatitis. External washing of the traditional Chinese medicine preparation of Example 2 of the present application, 1 course of treatment, the child's papules on the buttocks were reduced, and there was no exudate. Continue external washing for 2 courses of treatment, the child's papules on the buttocks subsided, and the appetite and sleep were normal. Follow-up after half a year showed no recurrence.

[0030] Chen, male, 10 months old. Diagnosed on June 26, 2022. The child had redness on the buttocks, a small amount of papules, scratching, obvious crying, emotional restlessness, poor appetite, refusal to eat, poor sleep, yellow urine, normal stool, pale red tongue, yellow and greasy fur, and slippery pulse. Diagnosed as infantile diaper dermatitis. External washing of the traditional Chinese medicine preparation of Example 2 of the present application, 1 course of treatment, the child's redness on the buttocks was reduced, and the crying was reduced. Continue external washing for 2 courses of treatment, the child's redness and papules on the buttocks subsided, and the appetite and sleep were normal. Follow-up after half a year showed no recurrence.

[0031] The above is only a preferred embodiment of the present application, it should be noted that for those skilled in the art, without departing from the concept of the present application, a number of modifications and improvements can be made, which should be considered as the protection scope of the present application, these will not affect the effect and practicality of the patent.

Claims

1. A traditional Chinese medicine preparation for treating diaper dermatitis, characterized in that, It consists of the following components by weight: 5-10g of Phellodendron bark, 5-10g of Sophora flavescens root, 5-10g of Kochia scoparia fruit, 5-10g of Sanguisorba officinalis root, 5-10g of Platycladus orientalis leaf, 5-10g of Lycium chinense root bark, 5-10g of Pogostemon cablin, and 5-10g of Polygonatum sibiricum.

2. The traditional Chinese medicine preparation for treating diaper dermatitis according to claim 1, characterized in that, It consists of the following components by weight: 10g of Phellodendron bark, 10g of Sophora flavescens root, 10g of Kochia scoparia fruit, 10g of Sanguisorba officinalis root, 10g of Platycladus orientalis leaf, 10g of Lycium chinense root bark, 10g of Pogostemon cablin, and 10g of Polygonatum sibiricum.

3. The traditional Chinese medicine preparation for treating diaper dermatitis according to claim 1, characterized in that, It consists of the following components by weight: 7-9g of Phellodendron bark, 7-9g of Sophora flavescens root, 7-9g of Kochia scoparia fruit, 7-9g of Sanguisorba officinalis root, 7-9g of Platycladus orientalis leaf, 7-9g of Lycium chinense root bark, 7-9g of Pogostemon cablin, and 7-9g of Polygonatum sibiricum.

4. A method for preparing a traditional Chinese medicine preparation for treating diaper dermatitis according to any one of claims 1-3, characterized in that, Includes the following steps: Weigh out appropriate amounts of each component according to the prescription, soak for 20-40 minutes, then decoct until 500 mL remains. Let stand until the liquid and precipitate separate into layers, filter and collect the liquid, bottle it into two portions, and set aside for later use.