A repairing and anti-aging composition and a repairing and anti-aging cosmetic

Through the combination composition of bee flower/leaf/stem water, sea anise callus culture filtrate, phytol and carboxymethyl beta-glucan sodium, the existing anti-aging ingredients are solved, and excellent anti-aging and repairing effects are achieved.

CN118453476BActive Publication Date: 2025-05-16SHANGHAI ZUNYA IND CO LTD

Patent Information

Application Number
CN202410665613.0
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-05-27
Publication Date
2025-05-16
Estimated Expiration
2044-05-27

AI Technical Summary

Technical Problem

The existing anti-aging ingredients are highly irritating when used in people with damaged skin barriers, and cannot effectively solve the anti-aging problem of people with damaged skin barriers.

Method used

The combination composition of four components, namely, bee flower/leaf/stem water, sea anise callus culture filtrate, phytol and carboxymethyl beta-glucan sodium, provides excellent anti-aging and repairing effects through its synergistic effect.

Benefits of technology

It achieves the ability to significantly improve the anti-aging effect while maintaining the stable state of the skin and reduces irritation, making it suitable for people with damaged skin barriers.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present application relates to the technical field of daily cosmetics, and specifically discloses a repairing and anti-aging composition and a repairing and anti-aging cosmetic. The active ingredients contained in the repairing and anti-aging composition include the following components in parts by weight: 0.994-7.952 parts of water from lemon balm / leaf / stem; 1-3 parts of filtrate from callus culture of sea fennel; 0.0015-0.005 parts of phytol; 0.9-4.5 parts of sodium carboxymethyl β-glucan. A repairing and anti-aging cosmetic is prepared from the above-mentioned repairing and anti-aging composition and cosmetic excipients. The repairing and anti-aging composition of the present application, which contains sodium carboxymethyl β-glucan, significantly enhances the antioxidant effect of the flavonoid components in the water from lemon balm / leaf / stem, thereby significantly improving the anti-aging effect.
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Description

Technical Field

[0001] The present application relates to the technical field of daily cosmetics, and more specifically, to a repairing and anti-aging composition and a repairing and anti-aging cosmetic. Background Art

[0002] Skin aging is a natural and progressive physiological process that directly affects the appearance and function of the skin. In order to delay aging, various anti-aging and anti-wrinkle products have emerged. However, due to sun exposure and other reasons, people's skin barriers will be damaged to varying degrees. These people with damaged skin barriers cannot use ingredients with strong anti-aging effects. Therefore, to solve the anti-aging problem of people with damaged skin barriers, the mildness of anti-aging ingredients must be given priority to achieve skin anti-aging while maintaining the skin's stable state.

[0003] Although the current high-efficiency anti-aging ingredients such as retinol, vitamin C, and acids have obvious anti-aging effects, they are also very irritating and are not suitable for people with damaged skin barriers. Plant extracts with anti-aging effects are mild, but the anti-aging effect is not good. Summary of the invention

[0004] In order to ensure that the product has excellent anti-aging effects while reducing irritation so as to be suitable for people with damaged skin barriers, the present application provides a repair and anti-aging composition and a repair and anti-aging cosmetic.

[0005] In the first aspect, the present application provides a repair and anti-aging composition, which adopts the following technical solution:

[0006] A repair and anti-aging composition, containing active ingredients including the following components in parts by weight:

[0007] Melissa flower / leaf / stem water 0.994-7.952 parts;

[0008] 1-3 parts of filtrate of callus culture of sea fennel;

[0009] Phytol 0.0015-0.005 parts;

[0010] Sodium carboxymethyl β-glucan 0.9-4.5 parts.

[0011] By adopting the above technical solution: the compound of the above four components, on the one hand, is less irritating than the strong anti-aging components, and has the effect of repairing the skin barrier, and at the same time has better anti-aging effect.

[0012] Melissa officinalis is a plant that contains rare aromatic essential oil molecules. Melissa officinalis / leaf / stem water contains aromatic ingredients such as β-caryophyllene, citral, citronellal, dianthin, etc., which have good sedative, soothing and anti-inflammatory effects. In addition, Melissa officinalis / leaf / stem water also contains polyphenols and flavonoids. Flavonoids can promote the synthesis of collagen, thereby reducing the formation of fine lines, fading existing wrinkles, and can also repair damaged skin and promote skin cell regeneration;

[0013] The filtrate of sea fennel callus culture is rich in various nutrients needed for growth and metabolism, which can promote the repair of dermal cells and the regeneration of epidermal cells, and promote the production of skin collagen;

[0014] Phytol is mainly found in plant lipids and is the main component of plant cell walls. The phytol selected in this application is mainly derived from the extract of Physcomitrella patens, which can help restore the health of skin epidermal cell nuclei, enhance the skin's ability to adapt to the environment, strengthen the quality of the skin barrier, and improve the skin's adaptability to changes in the external environment;

[0015] Melissa officinalis / leaf / stem water and sea fennel callus culture filtrate provide basic anti-aging effects, but the anti-aging effect of the four combined is significantly improved. The reason may be that the Melissa officinalis / leaf / stem water contains polyphenols and flavonoids. Flavonoids inhibit free Ca in cells. 2+ The increase in the level of β-glucan can inhibit the lipoxygenase LOX, thereby reducing the production of free radicals, while sodium carboxymethyl β-glucan can inhibit the Ca 2+ The influx of flavonoids into the skin can significantly enhance the antioxidant effect of flavonoids, thereby significantly improving the anti-aging effect.

[0016] Optionally, the active ingredient contained in the repair and anti-aging composition also includes black camellia seed oil.

[0017] By adopting the above technical solution: Black tea seed oil is an extract of the flower / leaf / vine of the bellflower, rich in oils and glycerols, which can be used to soften the skin and can also be used as a fragrance. It is rich in ω-3 / ω-6 fatty acids, which can be used to rebuild damaged skin barriers and relieve allergic reactions. It has a good effect on relieving skin eczema, strengthens the skin barrier, improves the ability to resist inflammation, reduces the deterioration of red blood streaks, prevents inflammation, and improves the overall appearance of skin with red blood streaks.

[0018] Optionally, the active ingredient contained in the repair and anti-aging composition also includes unsaponifiable matter of sunflower seed oil.

[0019] By adopting the above technical solution: Sunflower seed oil unsaponifiable matter is an extract of sunflower seed oil, which is rich in various vitamins, essential fatty acids and antioxidants. It can penetrate into the bottom layer of the skin, replenish the nutrients needed by the skin, promote metabolism, and enhance skin vitality. The active ingredients such as linoleic acid help to reduce pigmentation and inhibit melanin production, which has a significant effect on improving pigmentation problems. In addition, sunflower seed oil unsaponifiable matter can also strengthen the skin barrier function and delay aging.

[0020] Optionally, the active ingredient contained in the repair and anti-aging composition also includes sunflower seed oil.

[0021] By adopting the above technical solution: sunflower seed oil has a moisturizing effect, and has an anti-inflammatory effect of activating oxidase-activated receptors and promoting skin wound healing, has an inhibitory effect on tyrosinase, and can also play a whitening effect.

[0022] In the second aspect, the present application provides a repair and anti-aging cosmetic, which adopts the following technical solution:

[0023] A repairing and anti-aging cosmetic is prepared from the above-mentioned repairing and anti-aging composition and cosmetic auxiliary materials.

[0024] By adopting the above technical solution: adding a repairing and anti-aging composition, the corresponding efficacy of cosmetics is improved without irritation.

[0025] Optionally, the amount of the repair and anti-aging composition added to the cosmetic is 1-10%.

[0026] By adopting the above technical scheme: when the added amount of the repair and anti-aging composition is within the above range, it can be used to improve the efficacy of cosmetics. When the dosage is further increased, due to the small improvement in the repair and anti-aging efficacy, combined with factors such as cost, it is necessary to control the upper limit of the amount of the repair and anti-aging composition to 10%.

[0027] Optionally, the cosmetic is one of skin care lotion, lotion, essence, cream, facial mask liquid, and gel.

[0028] By adopting the above technical solution, it has a wider application range.

[0029] Optionally, the cosmetic is a cream, and the cosmetic excipients in the cream are: water, glycerin, allantoin, 1,2-pentanediol, carbomer, xanthan gum, sodium stearoyl glutamate, oil, lactobionic acid, levulinic acid, and sodium levulinate.

[0030] Optionally, the oil is one or more of C10-18 fatty acid triglycerides, castor seed oil, sweet almond oil and avocado oil.

[0031] In summary, this application has the following beneficial effects:

[0032] 1. The repair and anti-aging composition of the present application contains four products containing active ingredients, namely, lemon balm / leaf / stem water, sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan. It not only has a better repair effect, but also further adds sodium carboxymethyl β-glucan to the anti-aging effects of lemon balm / leaf / stem water and sea fennel callus culture filtrate. Through the synergistic effect between the four active substances and the synergistic effect between sodium carboxymethyl β-glucan and lemon balm / leaf / stem water, it exerts a significant anti-aging effect.

[0033] 2. The repair and anti-aging composition of the present application has good effects and good stability, and can be used in many types of cosmetics and has a wide range of uses;

[0034] 3. The repairing and anti-aging cosmetics of the present application are added with the repairing and anti-aging composition prepared in the present application, and the dosage thereof is limited to achieve a better repairing and anti-aging effect. DETAILED DESCRIPTION

[0035] The present application is further described in detail below with reference to the embodiments.

[0036] The lemon balm flower / leaf / stem water used in this application is collected from GOLGEMMA, with the trade name LEMON BALM GEOGARD CEBCOSMOS HYDROLATE HYDA0008, which contains 99.4% of lemon balm flower / leaf / stem water, 0.048% of dehydroacetic acid, 0.522% of benzyl alcohol, and 0.03% of water by weight percentage;

[0037] The filtrate of callus culture of sea fennel was collected from BIOTECH MARINE Company, trade name: CELTOSOMECRITHMUM MARITIMUM, content 100%;

[0038] Phytol was purchased from MIBELLE Company, trade name: MOSSCELLTEC No.1 (0571), containing 0.05% phytol, 5.995% water, and 94% isomalt by weight;

[0039] Sodium carboxymethyl β-glucan was obtained from MIBELLE Company, with the trade name CM-GLUCAN GRANULATE (0713), which contains 90% sodium carboxymethyl β-glucan, 5% water and 5% ethanol by weight percentage;

[0040] Ribes nigra seed oil, sunflower seed oil unsaponifiable matter, and sunflower seed oil are collected from RAHN Company, with the trade name DEFENSILPLUS, which contains, by weight percentage, 78.41% octyldodecanol, 17.5% ribes nigra seed oil, 2.5% unsaponifiable matter of sunflower (Helianthus annuus) seed oil, 0.5% cardiospermum halicabaum flower / leaf / vine extract, 0.5% tocopherol (vitamin E), 0.5% sunflower (Helianthus annuus) seed oil, and 0.09% rosemary (Rosmarinus officinalis) leaf extract;

[0041] Retinol was obtained from IRA Company with the trade name RETINOL 33.000 Ul / g CYCLOSYSTEM COMPLEX (25001), which contained 7.1% hydroxypropyl cyclodextrin, 1.03% retinol, 18.1% water, 15.61% caprylic / capric triglyceride, 0.2% tocopherol (vitamin E), 57.69% polysorbate-20, 0.2% sodium metabisulfite and 0.07% butylated hydroxytoluene by weight percentage;

[0042] Levulinic acid and sodium levulinate were obtained from EVONIK Company, with the trade name DERMOSOFT 700B, which contained 40% levulinic acid, 23% sodium levulinate, 17% glycerol, and 20% water by weight;

[0043] Allantoin was obtained from Shandong Ailitong New Materials Co., Ltd., with the trade name of allantoin (Ailitong), with a content of 100%; 1,2-pentanediol was obtained from SYMRISE, with the trade name of HYDROLITE 5GREEN, with a content of 100%;

[0044] Carbomer was obtained from LUBRIZOL ADVANCED MATERIALS, trade name CARBOPOL ULTREZ10POLYMER, content 100%;

[0045] Xanthan gum is obtained from CP KELCO US, INC. under the trade name CG-T XANTHAN GUM, content 100%;

[0046] Sodium stearoyl glutamate was obtained from BASF, trade name EUMULGIN SG, content 100%;

[0047] Lactobionic acid was obtained from SPEC CHEM INDUSTRY INC., with the trade name SPECKARE LBA (110034), with a content of 100%;

[0048] C10-18 fatty acid triglycerides were obtained from GATTEFOSSE, trade name LIPOCIRE A SG (5838), content 100%;

[0049] Castor seed oil was obtained from GUSTAV HEESS, trade name RHODICARE S, content 100%;

[0050] Sweet almond oil was obtained from A&A FRATELLIPARODI SPA, trade name PARYOL 480MR (MP 013392), content 100%;

[0051] Avocado tree butter was collected from A&A FRATELLIPARODI SPA, with the trade name PARYOL 218BK / R (MP017491) and a content of 100%.

[0052] Preparation Example 1

[0053] A repair and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), and CM-GLUCANGRANULATE (0713) in a weight ratio of 1:1:3:1, and the contents of lemon balm flower / leaf / stem water, sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan are as shown in Table 1.

[0054] Preparation Example 2

[0055] A repair and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), and CM-GLUCANGRANULATE (0713) in a weight ratio of 4.5:2:6:3, wherein the contents of lemon balm flower / leaf / stem water, sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan are as shown in Table 1.

[0056] Preparation Example 3

[0057] A repair and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), and CM-GLUCANGRANULATE (0713) in a weight ratio of 8:3:10:5, and the contents of lemon balm flower / leaf / stem water, sea fennel callus culture filtrate, phytol, and sodium carboxymethyl β-glucan are as shown in Table 1.

[0058] Comparative Preparation Example 1

[0059] A repair and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571) and CM-GLUCANGRANULATE (0713) in a weight ratio of 4:0.5:2:0.5, and the contents of lemon balm flower / leaf / stem water, sea fennel callus culture filtrate, phytol and carboxymethyl beta-glucan sodium are as shown in Table 1.

[0060] Comparative Preparation Example 2

[0061] A repair and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571) and CM-GLUCANGRANULATE (0713) in a weight ratio of 4:3.5:15:5.5, and the contents of lemon balm flower / leaf / stem water, sea fennel callus culture filtrate, phytol and carboxymethyl β-glucan sodium are as shown in Table 1.

[0062] Table 1 (unit: kg)

[0063]

[0064] Comparative Preparation Example 3

[0065] A repair and anti-aging composition, which is different from Preparation Example 2 in that it only contains LEMON BALMGEOGARD CEB COSMOS HYDROLATE HYDA0008, that is, it does not contain sea fennel callus culture filtrate, phytol and carboxymethyl β-glucan sodium.

[0066] Comparative Preparation Example 4

[0067] A repairing and anti-aging composition, which differs from Preparation Example 2 in that it contains only CM-GLUCANGRANULATE (0713), i.e., does not contain lemon balm / leaf / stem water, sea fennel callus culture filtrate, or phytol.

[0068] Comparative Preparation Example 5

[0069] A repairing and anti-aging composition, which is different from Preparation Example 2 in that it does not contain LEMON BALMGEOGARD CEB COSMOS HYDROLATE HYDA0008, that is, it does not contain lemon balm flower / leaf / stem water.

[0070] Comparative Preparation Example 6

[0071] A repair and anti-aging composition, which is different from Preparation Example 2 in that it does not contain CM-GLUCANGRANULATE (0713), that is, it does not contain sodium carboxymethyl β-glucan.

[0072] Preparation Example 4

[0073] A repairing and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), CM-GLUCANGRANULATE (0713), and DEFENSIL PLUS in a weight ratio of 4.5:2:6:3:2.

[0074] Preparation Example 5

[0075] A repairing and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), CM-GLUCANGRANULATE (0713), and DEFENSIL PLUS in a weight ratio of 4.5:2:6:3:6.

[0076] Preparation Example 6

[0077] A repairing and anti-aging composition is prepared by conventionally mixing LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008, CELTOSOME CRITHMUM MARITIMUM, MOSSCELLTEC No.1 (0571), CM-GLUCANGRANULATE (0713), and DEFENSIL PLUS in a weight ratio of 4.5:2:6:3:10.

[0078] Anti-aging test

[0079] 1. Determination of hydroxyl free radical scavenging rate

[0080] (1) Reagent configuration

[0081] FeSO4·7H2O solution: accurately weigh 2.224 g FeSO4·7H2O, dissolve it in 100 mL deionized water, mix well, take 10 mL, and make up to 100 mL to prepare 8 mmol / LFeSO4·7H2O solution.

[0082] H2O2 solution: Weigh 68 mg of 30% H2O2 solution, mix it with 1 mL of deionized water, and make up to 100 mL to prepare a 6 mmol / L H2O2 solution.

[0083] Sodium salicylate solution: Weigh 0.3202 g of sodium salicylate, dissolve it in an appropriate amount of deionized water, and make up to 100 mL to prepare a 20 mmol / L sodium salicylate solution.

[0084] Repair and anti-aging composition sample solution: Weigh 0.5 g of the repair and anti-aging composition in each preparation example or comparative preparation example and dissolve it in an appropriate amount of deionized water, add water to make the volume to 100 mL, and prepare an anti-aging composition sample mother solution with a mass concentration of 5 mg / mL. Then use the mother solution to prepare a sample solution with a mass concentration of 0.5 mg / mL for use.

[0085] (2) Hydroxyl free radical scavenging rate test

[0086] Add each reagent to four groups of test tubes according to the dosage shown in Table 3, and heat them in a 37°C water bath for 1 h. Then take an appropriate amount of solution and add it to a quartz cuvette. Measure the absorbance at a wavelength of 510 nm. Make 3 parallel groups for each experimental group.

[0087] Table 3 The amount of each reagent added in the hydroxyl free radical scavenging rate test

[0088]

[0089] The hydroxyl radical scavenging rate was calculated according to hydroxyl radical scavenging rate = [1-(A1-A2) / A0] x 100%.

[0090] Where A0 is the absorbance of group A0, where A1 is the absorbance of group A1, where A2 is the absorbance of group A2.

[0091] Test Results

[0092] Referring to the above-mentioned method for testing the hydroxyl radical scavenging rate, the test results of the preparation examples and the comparative preparation examples are recorded in the following table.

[0093] Table 4 Test results

[0094]

[0095]

[0096] According to Table 4, the test results of Preparation Example 2 and Comparative Preparation Examples 3 and 4 are compared. The sample solution contains lemon balm / leaf / stem water, sea fennel callus culture filtrate, phytol and sodium carboxymethyl β-glucan at the same time, and the scavenging rate of hydroxyl free radicals is significantly higher than that when only lemon balm / leaf / stem water or sodium carboxymethyl β-glucan is used, indicating that the four have a certain synergistic anti-aging effect after compounding. And the anti-aging and repairing effect of the composition of the present application is significantly better than that of the plant extract (lemon balm / leaf / stem water).

[0097] According to Table 4, the difference between Preparation Examples 5 and 6 and Preparation Example 2 is that the hydroxyl radical scavenging rate is significantly reduced due to the lack of lemon balm flower / leaf / stem water or sodium carboxymethyl β-glucan, indicating that only when the two are present at the same time, there is a significant anti-aging effect.

[0098] Examples 1-3, Comparative Examples 1-2

[0099] A cosmetic, which is a cream, wherein the components and their corresponding weights are shown in Table 5, and is prepared by the following steps:

[0100] Water, glycerin, allantoin, 1,2-pentanediol, carbomer, xanthan gum and sodium stearoyl glutamate were mixed and stirred at 80°C and 500 rpm for 20 min to obtain a first aqueous phase; oils (C10-18 fatty acid triglycerides, castor seed oil, sweet almond oil and avocado tree fat) were mixed and stirred at 80°C and 500 rpm for 10 min to obtain an oil phase; lactobionic acid and DERMOSOFT 700B were conventionally stirred and mixed to obtain a second aqueous phase;

[0101] Add the oil phase to the first aqueous phase, stir and mix, stop heating and continue stirring until the temperature reaches room temperature, then add the repair and anti-aging composition (prepared in Preparation Example 1) and the second aqueous phase, stir and mix, and the mixture is obtained.

[0102] Table 5 Components and their weights in Examples 1-3 and Comparative Examples 1-2 (kg)

[0103]

[0104]

[0105] Comparative Example 3

[0106] A cosmetic is a cream, which is different from Example 2 in that an equal amount of RETINOL 33.000 Ul / g CYCLOSYSTEM COMPLEX (25001) (containing 1.03% retinol) is used instead of the repair and anti-aging composition.

[0107] Examples 4-8, Comparative Examples 4-9

[0108] A cosmetic is a cream, which is different from Example 2 in that the use of the repair and anti-aging composition is shown in the following table, but the amount of the repair and anti-aging composition in the cream remains unchanged.

[0109] Table 6 Usage of the repair and anti-aging compositions in Examples 4-8 and Comparative Examples 4-9

[0110] Example 4 5 6 7 8 \ Preparation example of repair and anti-aging effect composition 2 3 4 5 6 \ Comparative Example 4 5 6 7 8 9 Comparative preparation examples of repair and anti-aging effect compositions 1 2 3 4 5 6

[0111] Performance Testing

[0112] The following performance tests were performed on the cosmetics prepared in the embodiments and comparative examples, and the test results are recorded in Table 7.

[0113] Detection Methods

[0114] 68 wrinkled subjects aged 35-40 with healthy skin were selected and divided into 17 groups, each with 4 subjects. The subjects in each group used the cosmetics prepared in Examples 1-8 and Comparative Examples 1-9 respectively. Usage: After cleansing the face, the subject took 0.5g of the cosmetics and applied it on the cheek area of ​​3*3cm, washed it off after 10 minutes, covered it once at 9 am and once at 6 pm, and the following test was performed at the same skin position:

[0115] 1. Wrinkle area change test:

[0116] The American facial image analyzer VISIA-CR was used to measure the wrinkle area of ​​the subjects before using cosmetics, which was recorded as the initial value. The wrinkle area was measured again after 7 days of continuous use, which was recorded as the ending value. Finally, the change rate of the wrinkle area was calculated, change rate = (initial value - ending value) / initial value. The larger the change rate, the better the anti-aging effect of the cosmetics.

[0117] 1. Test for changes in transepidermal water loss (TEWL): Use the German CK skin tester Tewameter TMHex to measure the transepidermal water loss of the test subjects before using cosmetics, and record it as the initial value. After 7 days of continuous use, the transepidermal water loss is measured again, and recorded as the termination value. Finally, the change rate of transepidermal water loss (TEWL) is calculated, change rate = (initial value - termination value) / initial value. The greater the change rate, the better the repair effect of the cosmetics.

[0118] 68 wrinkled subjects aged 35-40 with healthy skin were selected and divided into 17 groups, with 4 subjects in each group. The subjects in each group used the cosmetics prepared in Examples 1-8 and Comparative Examples 1-9, respectively, and the following tests were performed:

[0119] 1. Irritation test: According to the closed patch test method, the cosmetics were removed after 2 hours, and the skin reaction was observed at 0.5h, 24h, and 48h after the patch test. The skin irritation reaction was scored according to the skin reaction grading standard 5.3.2.1.3 in the "Procedures and Methods for Safety Evaluation of Cosmetics" GB7919-1987, with 0 points for the least irritation and 8 points for the most irritation.

[0120] Table 7 Performance test results

[0121]

[0122] According to Table 7, the test results of Examples 1-3 and Comparative Example 1 are compared. The wrinkle area change rate and TEWL change rate of the creams of Examples 1-3 increase with the increase in the amount of the repair and anti-aging composition; the data of the cream in Comparative Example 1 that does not contain the repair and anti-aging composition decreases significantly, indicating that the repair and anti-aging composition has enhanced the repair and anti-aging effect of the cosmetics. When the amount of the repair and anti-aging composition is increased from 5% to 10%, the effect improvement rate slows down. Considering the comprehensive cost, the amount of Example 2 is the best amount.

[0123] According to Table 7, the difference between Comparative Example 3 and Example 2 is that an equal amount of a product containing retinol is used to replace the repair and anti-aging composition, and the repair and anti-aging effects are similar, but the irritation is extremely high.

[0124] According to Table 7, Comparative Examples 6-9 are compared with Example 2. The difference between each comparative example and Example 2 is that: Comparative Example 6 uses an equal amount of the product LEMON BALM GEOGARD CEB COSMOS HYDROLATE HYDA0008 (containing lemon balm / leaf / stem water, without sea fennel callus culture filtrate, phytol and carboxymethyl β-glucan sodium) instead of the repair and anti-aging efficacy composition; Comparative Example 7 uses an equal amount of the product CM-GLUCAN GRANULATE (0713) (containing sodium carboxymethyl β-glucan, but excluding lemon balm / leaf / stem water, sea fennel callus culture filtrate, and phytol) replaces the repairing and anti-aging composition; the repairing and anti-aging composition of comparative example 8 does not contain lemon balm / leaf / stem water; the repairing and anti-aging composition of comparative example 9 does not contain sodium carboxymethyl β-glucan; from the results in Table 7, it can be seen that the wrinkle area change rate and TEWL change rate of the facial creams prepared in comparative examples 6-9 are significantly reduced, indicating that the cream has a significant effect only when the four components of the repairing and anti-aging composition of the present application are compounded.

[0125] It should be noted that the oils and fats in this application can be compounded by selecting one or more of C10-18 fatty acid triglycerides, castor seed oil, sweet almond oil and avocado oil. This application only briefly introduces the compounding of these four as an example.

[0126] 4. Stability test: The cosmetics were stored at -18 and 48°C for 30 days. No unstable conditions such as oil deterioration occurred, indicating good stability.

[0127] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make modifications to the present embodiment without any creative contribution as needed, but such modifications are protected by the patent law as long as they are within the scope of the claims of the present application.

Claims

1. A repair and anti-aging composition, characterized in that: The active ingredients contained include the following components in parts by weight: Melissa flower / leaf / stem water 0.994-7.952 parts; 1-3 parts of filtrate of callus culture of sea fennel; Phytol 0.0015-0.005 parts; Sodium carboxymethyl β-glucan 0.9-4.5 parts.

2. A repair and anti-aging composition according to claim 1, characterized in that: The active ingredient contained in the repair and anti-aging composition also includes black camellia seed oil.

3. A repair and anti-aging composition according to claim 1, characterized in that: The active ingredients contained in the repair and anti-aging composition also include unsaponifiable matter of sunflower seed oil.

4. A repair and anti-aging composition according to claim 1, characterized in that: The active ingredient contained in the repair and anti-aging composition also includes sunflower seed oil.

5. A repair and anti-aging cosmetic, characterized in that: The cosmetic is prepared from the repair and anti-aging composition and cosmetic accessories described in any one of claims 1 to 4.

6. A repair and anti-aging cosmetic according to claim 5, characterized in that: In the cosmetic, the amount of the repair and anti-aging composition added is 1-10%.

7. The repair and anti-aging cosmetic according to claim 5, characterized in that: The cosmetic is one of skin care lotion, emulsion, essence, cream, facial mask liquid and gel.

8. The repair and anti-aging cosmetic according to claim 7, characterized in that: The cosmetic is a cream, in which the cosmetic auxiliary materials are: water, glycerin, allantoin, 1,2-pentanediol, carbomer, xanthan gum, sodium stearoyl glutamate, oil, lactobionic acid, levulinic acid, and sodium levulinate.

9. A repair and anti-aging cosmetic according to claim 8, characterized in that: The oil is one or more of C10-18 fatty acid triglycerides, castor seed oil, sweet almond oil and avocado oil.

Citation Information

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