Use of a traditional Chinese medicine composition in the preparation of a medicament for treating intestinal injury
By regulating gut microbiota and immune response through a combination of traditional Chinese medicine, this method addresses the intestinal damage caused by a high-fat diet, improves intestinal barrier function, and suppresses inflammation, providing a safe and effective treatment method.
CN118453760BActive Publication Date: 2026-06-02SHIJIAZHUANG YILING PHARMA CO LTD
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SHIJIAZHUANG YILING PHARMA CO LTD
- Filing Date
- 2024-05-22
- Publication Date
- 2026-06-02
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Figure CN118453760B_ABST
Abstract
This invention relates to the application of a traditional Chinese medicine composition in the preparation of a drug for treating intestinal injury. The traditional Chinese medicine composition comprises: 50-150 parts of ginseng, 60-180 parts of polygonatum, 40-90 parts of atractylodes, 30-58 parts of sophora flavescens, 60-180 parts of ophiopogon japonicus, 60-110 parts of rehmannia glutinosa, 40-90 parts of polygonum multiflorum, 60-180 parts of cornus officinalis, 40-90 parts of poria cocos, 35-58 parts of eupatorium fortunei, 35-58 parts of coptis chinensis, 35-90 parts of anemarrhena asphodeloides, 35-58 parts of epimedium, 40-110 parts of salvia miltiorrhiza, 60-180 parts of kudzu root, 80-140 parts of litchi seed, and 40-90 parts of lycium chinense root bark. The above-mentioned traditional Chinese medicine composition can inhibit the expression of TNF, AGE-RAGE, TLR and IL-17 and the infiltration of macrophages. It also helps to regulate the proliferation and differentiation of intestinal cells, restore beneficial bacteria in the intestine, and significantly improve the barrier function of the intestine, thereby effectively improving the damaged intestinal function.
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