Pet antifungal ointment and preparation method thereof
By combining a specific ratio of Chinese herbal extracts with modern ointments, a pet anti-ringworm cream is prepared, which solves the problem of poor effect of existing pet psoriasis treatment, achieves rapid sterilization, itching relief and skin repair, and reduces the risk of recurrence.
Patent Information
- Application Number
- CN202410714068.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-04
- Publication Date
- 2025-10-17
- Estimated Expiration
- 2044-06-04
AI Technical Summary
Existing pet psoriasis treatment drugs have poor therapeutic effects, are irritating, easily develop drug resistance and are prone to recurrence. Traditional Chinese medicine is rarely used in the pet field.
A pet anti-ringworm cream is prepared by combining Chinese herbal extracts in a specific ratio with modern ointments, including ingredients such as glycerol, vitamin E oil, vaseline, menthol, ethanol solution, thymol and carbomer gum. The Chinese herbal extracts are composed of Stemona tuberosa, Dictamni bark, Kochia scoparia, Croton leaf, Sea red bean and Bambusa schrenckii root, and are prepared through a reasonable preparation process.
Pet anti-ringworm cream has the effects of rapid sterilization, anti-itching, and skin repair, reduces damage caused by scratching, improves the barrier function of the mucosa, has few side effects, and has significant and quick therapeutic effects.
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Figure CN118593420B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of pet antifungal technology, in particular to a pet antifungal ointment and a preparation method thereof. BACKGROUND
[0002] With the rapid development of economy and urbanization, in order to meet the spiritual life, more and more dogs, cats and other pets as companion animals into thousands of households. In the process of daily management of pets, due to the feeding concept of many pet owners has not fully adapted to the physiological characteristics of pets, often will appear to the pet overfeeding snacks, leading to vitamin deficiency in pets; excessive cleaning of pets, making the skin of pets keep wet state for a long time, and even destroy the skin mucosa barrier of pets; randomly use drugs, do not carry out regular internal and external deworming, etc., which has brought great threat to the health of pets, greatly increased the probability of pets getting sick.
[0003] Skin disease is the most common and easily induced disease in the process of pet feeding, and the most common skin disease is skin fungus, which is more difficult to treat than general skin infection, often accompanied by diffusion, infectivity, and even can be transmitted to pet owners, which must be paid attention to. Skin fungus such as cat fungus and dog fungus is mainly caused by fungal infection, and is accompanied by bacterial infection. The treatment of pet skin fungus currently mainly uses chemical drugs and disinfectant type drugs, which often have poor treatment effect and have certain irritation to the skin of pets. Pets are prone to hair loss, skin irritation, redness, itching, desquamation and other symptoms, and some can only be maintained, but long-term use will produce side effects such as drug resistance and easy recurrence. Traditional Chinese medicine has a long history in China and has very outstanding effect in external use of antifungal agents. It has small side effects and can cure many serious skin problems. However, the use of traditional Chinese medicine in the field of pets is relatively less, and the application of products is relatively blank, so the present application is proposed. SUMMARY
[0004] The present application aims to provide a pet antifungal ointment and a preparation method thereof. The pet antifungal ointment prepared by selecting raw materials has excellent bactericidal effect, can promote the repair of tissue damage, has excellent treatment effect on pet fungus, and has fast and significant effect.
[0005] In order to achieve the above-mentioned purpose of the present application, the following technical scheme is adopted:
[0006] The present application provides a pet antifungal ointment, which comprises the following components by weight percentage:
[0007] Glycerin 36%, Vitamin E oil 1%, Vaseline 0.05%, Menthol 0.02%, Ethanol solution 0.1%, Traditional Chinese medicine extract 2%, Musk amyl 0.05%, Carbomer glue 0.8%, Triethanolamine 0.02%, and the rest is water;
[0008] The traditional Chinese medicine extract is prepared from the following raw materials by weight:
[0009] Baihuopi 8-16 parts, Baishanpi 5-10 parts, Dishuizi 1-3 parts, Batouye 4-11 parts, Hairongdou 1-3 parts, and Zhuyepiaogen 3-8 parts.
[0010] Preferably, the pet antifungal ointment comprises the following components by weight percentage:
[0011] Glycerin 36%, Vitamin E oil 1%, Vaseline 0.05%, Menthol 0.02%, Ethanol solution 0.1%, Traditional Chinese medicine extract 2%, Musk amyl 0.05%, Carbomer glue 0.8%, Triethanolamine 0.02%, and the rest is water;
[0012] The traditional Chinese medicine extract is prepared from the following raw materials by weight:
[0013] Baihuopi 8-16 parts, Baishanpi 5-10 parts, Dishuizi 1-3 parts, Batouye 4-11 parts, Hairongdou 1-3 parts, and Zhuyepiaogen 3-8 parts.
[0014] Preferably, the traditional Chinese medicine extract is prepared by the following method:
[0015] (a) weigh each raw material according to the mass:
[0016] (b) put each crushed raw material into water for extraction to obtain an extraction liquid;
[0017] (c) combine, concentrate, and dry each extraction liquid to obtain the traditional Chinese medicine extract.
[0018] Preferably, the extraction comprises: putting the raw material into water at 80-100 ℃ according to the mass ratio of raw material to water of 1: (6-10) for 0.5-1 h, filtering, collecting the filtrate and the residue, adding water to the residue at 80-100 ℃ according to the mass ratio of raw material to water of 1: (6-10) for 0.5-1 h, filtering, collecting the filtrate, and combining the filtrates to obtain the extraction liquid.
[0019] Preferably, the concentration of the ethanol solution is 92%-98%.
[0020] The second aspect of the present application provides a preparation method of the above-mentioned pet antifungal ointment, which comprises the following steps:
[0021] (a) each component is weighed according to parts by weight:
[0022] (b) under stirring, add glycerol to carbomer and stir for a period of time, then add water and continue stirring until the carbomer is fully dissolved, stand for a period of time to obtain a glue solution;
[0023] (c) add triethanolamine, vitamin E oil, vaseline, menthol, ethanol solution, traditional Chinese medicine extract and thymol to the glue solution and stir evenly to obtain the pet antidermatophytic ointment.
[0024] Preferably, in step (b), glycerol is stirred for 2-4 min after being added.
[0025] Preferably, the standing for a period of time is 1-3 h.
[0026] Compared with the prior art, the pet antidermatophytic ointment has at least the following beneficial effects:
[0027] The pet antidermatophytic ointment is prepared by reasonably screening and matching traditional Chinese medicines, strictly screening drug sources, uniquely selecting traditional Chinese medicines, reasonably matching traditional Chinese medicines and appropriately controlling the amount of drugs.
[0028] Stachys Floridana has the effects of moistening the lungs to stop coughing and killing insects and lice, and is used to treat cough, phthisis, whooping cough, pinworm disease, body lice and tinea;
[0029] Cortex Dictamni has the effects of clearing heat and drying dampness, dispelling wind and relieving itching, and detoxification, and is used to treat wind rash, eczema, tinea, jaundice and damp-heat arthralgia;
[0030] Fructus Kochiae has the effects of clearing heat and draining dampness, dispelling wind and relieving itching, and is used to treat difficult urination, turbid urine, bloody dysentery, wind rash, eczema, tinea, skin itching and sores;
[0031] Croton Leaf has the effects of dispelling wind and activating blood, killing insects and detoxification, and is used to treat malaria, arthralgia, contusion and injury, tinea and snakebite;
[0032] Red Sea Bean has the effects of dispelling wind and clearing heat, drying dampness and relieving itching, and moisturizing the skin and beautifying the complexion, and is used to treat facial dark spots, acne, rhinophyma, facial wind and tinea versicolor;
[0033] Rhizoma Zanthoxyli has the effects of dispelling wind and cold, warming the middle and regulating qi, and activating blood and relieving pain, and is used to treat arthralgia due to wind and dampness, diarrhea, dysentery, laceration and bleeding, tinea and snakebite.
[0034] The beneficial effects of the present application are also embodied in that reasonable ointment raw material control, scientific production process, reasonable collocation of traditional Chinese medicine and modern ointment, good properties, pet owners can independently and quickly treat; The traditional Chinese medicine for treating tinea has strong adhesion on the tinea of pets, which can increase the contact area of the medicine and prolong the contact time; It has a unique smell, which can reduce the pet licking; It can quickly relieve itching, reduce the damage of the pet to the affected area caused by continuous scratching, and further reduce the risk of transmission; At the same time, the ointment can also increase the mucosal barrier, provide sufficient sterilization and repair time for traditional Chinese medicine, and improve the repair efficiency. Compared with traditional medicine, it is more convenient and fast, the effect is outstanding, and the effect is fast; The treatment is often more thorough, the skin is relatively mild, and the side effects are small. Therefore, under the joint action of reasonable raw materials and process, the prepared pet tinea ointment has excellent sterilization effect, excellent treatment effect, fast effect, and promotes the rapid recovery of tinea. BRIEF DESCRIPTION OF DRAWINGS
[0035] Figure 1 It is a microscope observation diagram of cat tinea in case 1 of the typical case of the present application;
[0036] Figure 2 It is a first day photograph of cat tinea in case 1 of the typical case of the present application;
[0037] Figure 3 It is a second day photograph of cat tinea in case 1 of the typical case of the present application;
[0038] Figure 4 It is a third day photograph of cat tinea in case 1 of the typical case of the present application;
[0039] Figure 5 It is a fourth day photograph of cat tinea in case 1 of the typical case of the present application;
[0040] Figure 6 It is a sixth day photograph of cat tinea in case 1 of the typical case of the present application;
[0041] Figure 7 It is a seventh day photograph of cat tinea in case 1 of the typical case of the present application;
[0042] Figure 8 It is a microscope observation diagram of cat tinea in case 2 of the typical case of the present application;
[0043] Figure 9 It is a first day photograph of cat tinea in case 2 of the typical case of the present application;
[0044] Figure 10 It is a second day photograph of cat tinea in case 2 of the typical case of the present application;
[0045] Figure 11The third day photograph of the cat tinea of case 2 in the typical case of the present application;
[0046] Figure 12 The fourth day photograph of the cat tinea of case 2 in the typical case of the present application;
[0047] Figure 13 The sixth day photograph of the cat tinea of case 2 in the typical case of the present application;
[0048] Figure 14 The seventh day photograph of the cat tinea of case 2 in the typical case of the present application. DETAILED DESCRIPTION
[0049] The technical solutions of the present application will be described in detail below with examples. The following examples are only used to more clearly illustrate the technical solutions of the present application, and therefore only serve as examples, and cannot limit the protection scope of the present application.
[0050] It should be noted that, unless otherwise specified, the technical terms or scientific terms used in the present application should be understood as the usual meanings understood by the skilled in the art to which the present application belongs.
[0051] Example 1
[0052] The present example is a pet tinea-removing ointment, which comprises the following components in weight percentage:
[0053] glycerol 32%, vitamin E oil 0.8%, vaseline 0.08%, menthol 0.01%, ethanol solution 0.8%, traditional Chinese medicine extract 0.5%, musk ampernol 0.08%, carbomer glue 0.6%, triethanolamine 0.01%, and the balance is water;
[0054] The traditional Chinese medicine extract is prepared from the following traditional Chinese medicine raw materials in weight parts:
[0055] 100 parts of Radix Stachyuri, 5 parts of Cortex Phellodendri, 3 parts of Fructus Kochiae, 4 parts of leaf of Croton tiglium, 3 parts of sea red beans, and 3 parts of root of Zanthoxylum armatum DC;
[0056] The concentration of the ethanol solution is 92%;
[0057] The traditional Chinese medicine extract is prepared by the following method:
[0058] (a) each raw material is weighed according to the mass:
[0059] (b) according to the mass ratio of raw material to water of 1:6, the raw material is placed in water at 100℃ for 0.5h, filtered, and the filtrate and filter residue are collected, and then according to the mass ratio of raw material to water of 1:6, water is added to the filter residue at 100℃ for 0.5h, filtered, and the filtrate is collected, and the filtrates are combined to obtain the extract;
[0060] (c) combining, concentrating, and drying the extracts to obtain the Chinese herbal medicine extract.
[0061] The preparation method of the above-mentioned pet anti-ringworm ointment comprises the following steps:
[0062] (a) Weigh each component according to weight:
[0063] (b) adding glycerol to the carbomer with stirring for 2 minutes, then adding water and continuing to stir until the carbomer is fully dissolved, and then allowing to stand for 3 hours to obtain a gel;
[0064] (c) adding triethanolamine, vitamin E oil, vaseline, menthol, ethanol solution, Chinese herbal extract and thymol to the glue and stirring well to obtain the pet anti-ringworm ointment.
[0065] Example 2
[0066] This embodiment is a pet anti-ringworm ointment, which includes the following components in percentage by weight:
[0067] Glycerol 40%, vitamin E oil 1.2%, petrolatum 0.02%, menthol 0.03%, ethanol solution 1.2%, Chinese herbal medicine extract 3%, thymol 0.03%, carbomer gel 1%, triethanolamine 0.03%, and the balance is water;
[0068] The Chinese medicine extract is prepared from the following Chinese medicine raw materials in parts by weight:
[0069] 8 parts of Stemona tuberosa, 10 parts of Dictamnus cortex, 1 part of Kochia scoparia fruit, 11 parts of Croton tiglium leaves, 1 part of Crimson Beans, and 8 parts of Bamboo Leaf and Pepper Root;
[0070] The concentration of the ethanol solution is 98%;
[0071] The Chinese medicine extract is prepared by the following method:
[0072] (a) Weigh each raw material by mass:
[0073] (b) extracting the raw material with water at a mass ratio of raw material to water of 1:10 at 80°C for 1 hour, filtering, collecting the filtrate and filter residue, then adding water to the filter residue at a mass ratio of raw material to water of 1:10, extracting at 80°C for 1 hour, filtering, collecting the filtrate, and combining the filtrates to obtain an extract;
[0074] (c) combining, concentrating, and drying the extracts to obtain the Chinese herbal medicine extract.
[0075] The preparation method of the above-mentioned pet anti-ringworm ointment comprises the following steps:
[0076] (a) Weigh each component according to weight:
[0077] (b) adding glycerol into carbomer under stirring condition, stirring for 4 min, then adding water and continuing to stir until carbomer is fully dissolved, standing for 1 h to obtain a glue solution;
[0078] (c) adding triethanolamine, vitamin E oil, vaseline, menthol, ethanol solution, traditional Chinese medicine extract and thymol into the glue solution and stirring evenly to obtain the pet antidermatosis ointment.
[0079] Example 3
[0080] The pet antidermatosis ointment comprises the following components in weight percentage:
[0081] glycerol 36%, vitamin E oil 1%, vaseline 0.05%, menthol 0.02%, ethanol solution 0.1%, traditional Chinese medicine extract 2%, thymol 0.05%, carbomer glue 0.8%, triethanolamine 0.02%, and the balance being water;
[0082] The traditional Chinese medicine extract is prepared from the following traditional Chinese medicine raw materials in weight parts:
[0083] 100 parts of Radix Stemonae, 80 parts of Cortex Phellodendri, 2 parts of Fructus Kochiae, 80 parts of leaf of Croton tiglium, 2 parts of sea red beans and 5 parts of root of Zanthoxylum armatum DC;
[0084] The concentration of the ethanol solution is 95%;
[0085] The traditional Chinese medicine extract is prepared by the following method:
[0086] (a) weighing each raw material according to the mass:
[0087] (b) according to the mass ratio of raw material to water being 1:8, the raw material is extracted in water at 90°C for 0.8 h, filtered, and the filtrate and residue are collected, then according to the mass ratio of raw material to water being 1:8, water is added to the residue and extracted at 90°C for 0.8 h, filtered, and the filtrate is collected, and the filtrates are combined to obtain the extract;
[0088] (c) combining, concentrating and drying each extract to obtain the traditional Chinese medicine extract.
[0089] The preparation method of the above-mentioned pet antidermatosis ointment comprises the following steps:
[0090] (a) weighing each component according to the weight parts:
[0091] (b) adding glycerol into carbomer under stirring condition, stirring for 3 min, then adding water and continuing to stir until carbomer is fully dissolved, standing for 2 h to obtain a glue solution;
[0092] (c) adding triethanolamine, vitamin E oil, vaseline, menthol, ethanol solution, traditional Chinese medicine extract and thymol to the glue solution and stirring evenly, to obtain the pet antifungal ointment.
[0093] Comparative Example 1
[0094] The pet antifungal ointment comprises the following components by weight percentage:
[0095] glycerol 36%, vitamin E oil 1%, vaseline 0.05%, menthol 0.02%, ethanol solution 0.1%, traditional Chinese medicine extract 2%, thymol 0.05%, carbomer glue 0.8%, triethanolamine 0.02%, and the balance is water;
[0096] The traditional Chinese medicine extract is prepared from the following traditional Chinese medicine raw materials by weight:
[0097] Radix Stemonae 17 parts, Cortex Meliae 8 parts, Fructus Kochiae 2 parts, leaf of Croton tiglium 8 parts and sea red bean 2 parts;
[0098] The concentration of the ethanol solution is 95%;
[0099] The traditional Chinese medicine extract is prepared by the following method:
[0100] (a) weighing each raw material according to the mass:
[0101] (b) placing the raw materials in water at 90°C for extraction for 0.8 h according to the mass ratio of raw material to water of 1:8, filtering, collecting the filtrate and filter residue, adding water to the filter residue at 90°C for extraction for 0.8 h according to the mass ratio of raw material to water of 1:8, filtering, collecting the filtrate, and combining the filtrates to obtain the extract;
[0102] (c) combining, concentrating and drying each extract to obtain the traditional Chinese medicine extract.
[0103] The preparation method of the pet antifungal ointment comprises the following steps:
[0104] (a) weighing each component according to the weight parts:
[0105] (b) adding glycerol to the carbomer under stirring for 3 min, then adding water and continuing to stir until the carbomer is fully dissolved, and placing for 2 h to obtain a glue solution;
[0106] (c) adding triethanolamine, vitamin E oil, vaseline, menthol, ethanol solution, traditional Chinese medicine extract and thymol to the glue solution and stirring evenly, to obtain the pet antifungal ointment.
[0107] Comparative Example 2
[0108] The comparative example is a pet antifungal ointment comprising the following components by weight percentage:
[0109] Glycerol 36%, vitamin E oil 1%, vaseline 0.05%, menthol 0.02%, ethanol solution 0.1%, traditional Chinese medicine extract 2%, thymol 0.05%, carbomer glue 0.8%, triethanolamine 0.02%, and the balance is water;
[0110] The traditional Chinese medicine extract is prepared from the following traditional Chinese medicine raw materials by weight:
[0111] Stemona 20 parts, Dictamnus 8 parts, Fructus Kochiae 2 parts, sea red bean 2 parts, and bamboo leaf pepper root 5 parts;
[0112] The concentration of the ethanol solution is 95%;
[0113] The traditional Chinese medicine extract is prepared by the following method:
[0114] (a) Each raw material is weighed by mass:
[0115] (b) According to the mass ratio of raw material to water of 1:8, the raw material is placed in water at 90°C for 0.8h, filtered, and the filtrate and filter residue are collected. Then, according to the mass ratio of raw material to water of 1:8, water is added to the filter residue at 90°C for 0.8h, filtered, and the filtrate is collected. The filtrates are combined to obtain the extract;
[0116] (c) The extracts are combined, concentrated, and dried to obtain the traditional Chinese medicine extract.
[0117] The preparation method of the pet antifungal ointment described above comprises the following steps:
[0118] (a) Each component is weighed by weight:
[0119] (b) Under stirring conditions, glycerol is added to carbomer and stirred for 3min. Then, water is added and stirred until the carbomer is fully dissolved. After standing for 2h, a glue solution is obtained;
[0120] (c) Triethanolamine, vitamin E oil, vaseline, menthol, ethanol solution, traditional Chinese medicine extract, and thymol are added to the glue solution and stirred evenly to obtain the pet antifungal ointment.
[0121] Comparative Example 3
[0122] The example is a pet antifungal ointment comprising the following components by weight percentage:
[0123] Glycerin 36%, Vitamin E oil 1%, Vaseline 0.05%, Menthol 0.02%, Ethanol solution 0.1%, Traditional Chinese medicine extract 2%, Thymol 0.05%, Carbomer glue 0.8%, Triethanolamine 0.02%, and the rest is water;
[0124] The traditional Chinese medicine extract is prepared from the following raw materials by weight:
[0125] Stachys 12 parts, Cnidium 8 parts, Semen Kochiae 2 parts, Croton leaf 8 parts, Red bean 2 parts, and Bamboo leaf pepper root 5 parts;
[0126] The concentration of the ethanol solution is 95%;
[0127] The traditional Chinese medicine extract is prepared by the following method:
[0128] (a) Each raw material is weighed according to the mass:
[0129] (b) According to the mass ratio of raw material to water of 1:8, the raw material is placed in water at 90°C for 0.8h, filtered, and the filtrate and residue are collected. Then, according to the mass ratio of raw material to water of 1:8, water is added to the residue at 90°C for 0.8h, filtered, and the filtrate is collected. The filtrates are combined to obtain the extract;
[0130] (c) The extracts are combined, concentrated, and dried to obtain the traditional Chinese medicine extract.
[0131] The preparation method of the pet antifungal ointment described above comprises the following steps:
[0132] (a) Each component is weighed according to the weight parts:
[0133] (b) Under stirring conditions, glycerin is added to carbomer and stirred for 3min. Then, water is continuously stirred until the carbomer is fully dissolved. After 2h, the glue liquid is obtained;
[0134] (c) Triethanolamine, Vitamin E oil, Vaseline, Menthol, ethanol solution, traditional Chinese medicine extract, and thymol are added to the glue liquid and stirred evenly to obtain the pet antifungal ointment.
[0135] Experimental example
[0136] The pet antifungal ointments prepared by Example 3 and Comparative Examples 1-3 are obtained respectively;
[0137] The pet antifungal ointments of Example 3 and Comparative Examples 1-3 are used to treat 30 pet cats with cat tinea respectively.
[0138] Treatment method: The pet antifungal ointment is applied to the cat tinea position, and applied once in the morning and once in the evening every day, for 7 days.
[0139] Therapeutic effect judgment:
[0140] Effective: cat dandruff area reduced by more than 80%;
[0141] Effective: cat dandruff area reduced by more than 80%;
[0142] Ineffective: cat dandruff area reduced by less than 10%, or no change or even increased.
[0143] The statistical results are shown in Table 1:
[0144] Table 1 Treatment effect of cat dandruff
[0145]
[0146] From Table 1, it can be seen that:
[0147] The pet dandruff ointment prepared by the examples and comparative examples of the present application has a certain therapeutic effect, compared with the comparative examples, the pet dandruff ointment prepared by the examples of the present application has better therapeutic effect, and has better curative effect in a shorter time.
[0148] Typical cases:
[0149] 1. Variety: English short, age: 6.5 months, male, weight: 2.4 kg, body temperature: 38.3℃, no history of any previous disease, clinical diagnosis: touching the body is relatively smooth, a larger scab is found at the neck, and blood oozes out after being pulled open; as shown in Figure 1 , a large number of microspores exist in routine tests, and the pet dandruff ointment of Example 3 is used for treatment, which is applied once in the morning and evening, and the situations of the first to seventh days, the first to fourth days and the sixth to seventh days are shown in Figures 2-7 , respectively.
[0150] 2. Variety: English short, age: 4 months, male, weight: 1.9 kg, body temperature: 38.7℃, infected with herpes virus when just out of the nest, no history of any previous disease, clinical diagnosis: touching the whole hair is relatively smooth, the internal dandruff is relatively more when the hair is pulled apart, and the hair loss is relatively serious, and there is also a circular hair loss scab at the back of the neck; as shown in Figure 8 , a large number of microspores and a certain amount of coccus exist in routine tests, and the pet dandruff ointment of Example 3 is used for treatment, which is applied once in the morning and evening, and the situations of the first to seventh days, the first to fourth days and the sixth to seventh days are shown in Figures 9-14 , respectively.
[0151] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, and are not intended to limit the present application; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that the technical solutions recorded in the foregoing embodiments can still be modified, or some or all of the technical features can be replaced by equivalents; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application, and they should be covered in the scope of the claims and the description of the present application.
Claims
1. A pet anti-ringworm ointment, characterized in that: The pet anti-ringworm ointment comprises the following components in percentage by weight: Glycerol 32%-40%, vitamin E oil 0.8%-1.2%, petrolatum 0.02%-0.08%, menthol 0.01%-0.03%, ethanol solution 0.8%-1.2%, traditional Chinese medicine extract 0.5%-3%, thymol 0.03%-0.08%, carbomer gel 0.6%-1%, triethanolamine 0.01%-0.03%, and the balance is water; The Chinese medicine extract is prepared from the following Chinese medicine raw materials in parts by weight: 8-16 parts of Stemona tuberosa, 5-10 parts of Dictamnus cortex, 1-3 parts of Kochia scoparia fruit, 4-11 parts of Croton tiglium leaves, 1-3 parts of Sea Red Beans, and 3-8 parts of Bamboo Leaf and Pepper Root.
2. The pet anti-ringworm ointment according to claim 1, characterized in that The pet anti-ringworm ointment comprises the following components in percentage by weight: Glycerol 36%, vitamin E oil 1%, petrolatum 0.05%, menthol 0.02%, ethanol solution 0.1%, Chinese herbal medicine extract 2%, thymol 0.05%, carbomer gel 0.8%, triethanolamine 0.02%, the balance is water; The Chinese medicine extract is prepared from the following Chinese medicine raw materials in parts by weight: 12 parts of Stemona tubers, 8 parts of Dictamnus cortex, 2 parts of Kochia scoparia fruit, 8 parts of Croton tiglium leaves, 2 parts of Sea Red Beans and 5 parts of Bamboo Leaf and Pepper Root.
3. The pet anti-ringworm ointment according to claim 1, characterized in that The Chinese medicine extract is prepared by the following method: (a) Weigh each raw material by mass: (b) extracting the crushed raw materials in water to obtain extracts; (c) combining, concentrating, and drying the extracts to obtain the Chinese herbal medicine extract.
4. The pet anti-ringworm ointment according to claim 3, characterized in that The extraction comprises: placing the raw material in water at a mass ratio of raw material to water of 1:(6-10) for extraction at 80-100°C for 0.5-1 hour, filtering, collecting the filtrate and filter residue, then adding water to the filter residue at a mass ratio of raw material to water of 1:(6-10) for extraction at 80-100°C for 0.5-1 hour, filtering, collecting the filtrate, and combining the filtrates to obtain an extract.
5. The pet anti-ringworm ointment according to claim 1, characterized in that The concentration of the ethanol solution is 92% to 98%.
6. The method for preparing the pet anti-tinea ointment according to any one of claims 1 to 5, wherein: The steps include: (a) Weigh each component according to weight: (b) adding glycerol to the carbomer under stirring and stirring for a period of time, then adding water and continuing to stir until the carbomer is fully dissolved, and allowing to stand for a period of time to obtain a gel; (c) adding triethanolamine, vitamin E oil, vaseline, menthol, ethanol solution, Chinese herbal extract and thymol to the glue and stirring well to obtain the pet anti-ringworm ointment.
7. The preparation method according to claim 6, characterized in that In the step (b), the mixture is stirred for 2 to 4 minutes after the glycerol is added.
8. The preparation method according to claim 6, characterized in that The placement period is 1 to 3 hours.
Citation Information
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