A high-concentration multi-collagen peptide composition and its preparation method and application

By adding a variety of collagen peptides and auxiliary ingredients to the collagen peptide composition, the stability and absorption effect of the composition are improved, the problem of low collagen peptide content in the prior art is solved, and the skin's moisturizing, anti-sugar and anti-oxidation ability is significantly improved.

CN118661858BActive Publication Date: 2025-03-28JILIN HENGMEI YUCHUANG HEALTH TECH CO LTD +1
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Patent Information

Application Number
CN202411149638.1
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-08-21
Publication Date
2025-03-28
Estimated Expiration
2044-08-21

AI Technical Summary

Technical Problem

The content of collagen peptides in the prior art is relatively low, and there is still room for improvement in the skin's moisturizing, anti-sugar and antioxidant abilities.

Method used

Provided is a high concentration of multiple collagen peptide composition, including a mixture of collagen peptide A, elastin peptide, collagen peptide B, ray collagen peptide and fish oligopeptide, combining sodium hyaluronate, pectin and konjac gum, to improve the stability and absorption effect of collagen peptide by controlling the mass ratio of these components.

Benefits of technology

It significantly improves the skin's moisturizing, anti-sugar and anti-oxidant abilities, enhances the skin's elasticity and water retention effect, and delays skin aging.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention provides a high-concentration multiple collagen peptide composition and its preparation method and application, relates to the field of food, the high-concentration collagen peptide composition includes 420-560 parts of collagen peptide, 20-40 parts of xylitol, 0.5-2 parts of sodium hyaluronate, 0.1-0.2 parts of pectin and 0.1-0.2 parts of konjac gum, and the collagen peptide is a mixture of collagen peptide A, elastin peptide, collagen peptide B, skate collagen peptide and fish oligopeptide. The collagen peptide composition in the present invention has a high content of multiple collagen peptides, good taste and good stability, and can help improve the moisturizing, sugar resistance and antioxidant ability of the skin.
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Description

Technical Field

[0001] The present invention relates to the field of food, and in particular to a high-concentration multiple collagen peptide composition, a preparation method and application thereof. Background Art

[0002] Collagen peptides are a type of product with a relative molecular mass of less than 10,000 Da, which is produced by extraction, hydrolysis and refining of fresh animal tissues rich in collagen (including skin, bones, tendons, tendons, scales, etc.). Compared with its precursor native collagen, collagen peptides have a lower molecular weight, so they are easy to digest and absorb by the human body. At the same time, the unique Gly-Pro-Hyp sequence of collagen peptides also gives them unique physical and chemical properties and biological activity. They can not only be used as health foods, beauty products, and packaging materials, but also as food additives in meat product improvement, frozen foods, beverages, cakes and dairy products.

[0003] For compositions containing collagen peptides, the prior art, such as patent CN111938159A, discloses a collagen peptide composition and its oral liquid and preparation method, which includes the following raw materials: 1-10 parts of blueberry juice, 8-17 parts of fish collagen peptides, 1-7 parts of polysaccharide alcohols, 0.1-1.5 parts of oil components, 0.5-5 parts of unsaturated fatty acids, and 0.01-0.1 parts of vitamins. After long-term drinking, the oral liquid in the invention has good antioxidant, anti-ultraviolet damage, beauty and skin care, and spot lightening and wrinkle removal effects. However, the content of collagen peptides in the invention is relatively low.

[0004] For example, patent CN115844022A discloses an oral cosmetic composition containing collagen peptide and vitamin C and its use, which contains collagen peptide, vitamin C, elastin peptide, γ-aminobutyric acid (GABA) and blood orange powder, and can effectively regulate skin biorhythm, promote the secretion of collagen peptide in the skin, improve wrinkles, and reduce skin pigmentation. However, the moisturizing, anti-sugar and anti-oxidation capabilities of the composition in this invention still have room for further improvement.

[0005] For example, Chinese patent CN116268253A discloses a sodium hyaluronate collagen peptide solid beverage and a preparation method thereof, wherein the solid beverage comprises the following components by weight: 0.5-2 parts of sodium hyaluronate, 40-80 parts of collagen peptide, 1-5 parts of vitamin C, and 1-5 parts of vitamin E. 0.01-0.02 parts and 10-50 parts of functional excipients. During the preparation, sodium hyaluronate, collagen peptide, vitamin C, vitamin E and optional functional excipients are first disinfected and sterilized in a clean area, and then the disinfected and sterilized materials are sieved to obtain uniform materials, and then the formula amount of sodium hyaluronate, collagen peptide, vitamin C, vitamin E and optional functional excipients are weighed, and each material is added to a clean column hopper mixer for mixing to obtain a uniformly mixed material, and finally the uniformly mixed material is loaded into a granule packaging machine, and granule packaging is continued according to the set inner packaging net content to obtain a sodium hyaluronate collagen solid beverage. However, the type of collagen peptides in the solid beverage in this invention is relatively single, and it is not possible to supplement a variety of collagens more comprehensively.

[0006] In view of the problems existing in the prior art, it is necessary to find a high-concentration multiple collagen peptide composition and a preparation method and application thereof. Summary of the invention

[0007] In view of the problems existing in the prior art, the present invention provides a high-concentration multiple collagen peptide composition and a preparation method and application thereof. The collagen peptide composition has a high content of collagen peptides, good taste and good stability, and can help improve the skin's moisturizing, anti-sugar and anti-oxidation abilities.

[0008] To achieve the above purpose, the technical solution adopted by the present invention is as follows:

[0009] The invention provides a high-concentration multiple collagen peptide composition, which comprises, by weight, 420-560 parts of collagen peptide, 20-40 parts of xylitol, 0.5-2 parts of sodium hyaluronate, 0.1-0.2 parts of pectin and 0.1-0.2 parts of konjac gum.

[0010] Wherein, the collagen peptide is a mixture of collagen peptide A, elastin peptide, collagen peptide B, ray collagen peptide and fish oligopeptide;

[0011] The mass ratio of the collagen peptide A, elastin peptide, collagen peptide B, skate collagen peptide and fish oligopeptide is 40-48:0.4-2:2-4:0.2-1:0.2-1.

[0012] Preferably, the mass ratio of the collagen peptide A, elastin peptide, collagen peptide B, skate collagen peptide and fish oligopeptide is 45:1:3:0.5:0.5.

[0013] As some preferred embodiments, the collagen peptide composition includes, by weight, 400-480 parts of collagen peptide A, 4-20 parts of elastin peptide, 20-40 parts of collagen peptide B, 2-10 parts of ray collagen peptide, 2-10 parts of fish oligopeptide, 20-40 parts of xylitol, 0.5-2 parts of sodium hyaluronate, 0.1-0.2 parts of pectin and 0.1-0.2 parts of konjac gum.

[0014] As other preferred embodiments, the collagen peptide composition includes, by weight, 420-460 parts of collagen peptide A, 8-15 parts of elastin peptide, 25-35 parts of collagen peptide B, 4-8 parts of ray collagen peptide, 4-8 parts of fish oligopeptide, 25-35 parts of xylitol, 1-2 parts of sodium hyaluronate, 0.15-0.2 parts of pectin and 0.15-0.2 parts of konjac gum.

[0015] As a preferred embodiment, the mass ratio of the sodium hyaluronate, pectin and konjac gum is 5-15:1:1; preferably 10:1:1.

[0016] As a preferred embodiment, the collagen peptide composition comprises, by weight, 450 parts of collagen peptide A, 10 parts of elastin peptide, 30 parts of collagen peptide B, 5 parts of skate collagen peptide, 5 parts of fish oligopeptide, 30 parts of xylitol, 1.5 parts of sodium hyaluronate, 0.15 parts of pectin and 0.15 parts of konjac gum.

[0017] The composition of the present invention is based on a mixture of collagen peptide A, elastin peptide, collagen peptide B, skate collagen peptide and fish oligopeptides. The combination of multiple collagen peptides can better improve the skin moisturizing effect, increase the collagen content, and enable the composition to better improve skin elasticity and improve the skin's water retention effect.

[0018] Among them, collagen peptide A: the average molecular weight is less than 1000Da. Its function is to maintain the morphology and structure of the skin and tissues and organs, and it is also an important raw material for repairing damaged tissues. Collagen and fibroblasts in the dermis of the skin complement each other and provide support for the skin. When collagen metabolism is normal, the dense collagen fibers can play an effective supporting role; after skin aging, the partial loss of collagen will cause the collagen peptide bonds and elastic network supporting the skin to break, and its structure will be destroyed. The skin tissue will be oxidized, atrophied, and collapsed, and the skin will show aging phenomena such as dryness, wrinkles, sagging and inelasticity. Therefore, to delay aging, collagen must be supplemented in time to ensure that the collagen content in the skin is sufficient.

[0019] Elastin peptide: It is an important protein in connective tissue, named for its elastic properties. It is mainly found in elastic tissues and organs such as animal arteries, ligaments, cartilage, lungs and skin. Elastin accounts for 2% of the total dermal protein and coexists with collagen at a ratio of 1:10. It can give tissues elasticity and tensile strength and plays an important role in skin aging. Its degradation and destruction will cause skin elasticity loss, sagging, various wrinkles, and even patches and nodules that lose skin color.

[0020] Collagen peptide B: average molecular weight less than 500Da, CTP content higher than 30%, GPH content higher than 3.4%. It has significant effects on skin moisturizing, skin wrinkle prevention, bone health and hair quality. It can promote the synthesis of collagen, increase the content of hyaluronic acid in the body, and achieve the effect of moisturizing, plumping and firming the skin.

[0021] Ray Collagen Peptide: Unique composition and golden ratio, collagen peptide + glycosaminoglycan GAGs (chondroitin sulfate, glucosamine, hyaluronic acid, etc.). Selected from marine cartilaginous fish, rich in collagen and glycosaminoglycan GAGs (100%), unique proteoglycan ingredients, can retain matrix moisture, lock in moisture and maintain the skin support structure.

[0022] Fish oligopeptides: Rich in tetrapeptides (proline (or hydroxyproline)-glycine-X-arginine), they can competitively react with glucose or other sugar derivatives in the body, thereby blocking the cross-linking of proteins in the body to form AGEs, thereby playing an anti-glycation role.

[0023] The invention further adds sodium hyaluronate, pectin and konjac gum. Sodium hyaluronate has the functions of moisturizing and repairing the skin, and can increase the elasticity and softness of the skin. Pectin contains a variety of polysaccharides with strong antioxidant capacity, can neutralize free radicals, reduce oxidative damage, and has a certain effect on delaying aging. Konjac gum is rich in collagen, starch, etc., and can effectively increase satiety after penetrating into the body. In addition, it can promote the discharge of intestinal waste, accelerate intestinal peristalsis, and improve constipation. In the implementation process, it is unexpectedly found that by controlling the mass ratio of sodium hyaluronate, pectin and konjac gum, the stability of collagen peptide can be significantly improved, and the collagen peptide can be better absorbed, so that the composition can have better moisturizing, anti-sugar and anti-oxidation effects.

[0024] As some preferred embodiments, the collagen peptide composition further comprises, by weight, 0.01-0.02 parts of zinc gluconate, 0.05-0.1 parts of vitamin C, 0.05-0.1 parts of vitamin E, 0.005-0.01 parts of sweeteners and 0.01-0.02 parts of acidulants.

[0025] Wherein, the sweetener includes steviol glycoside and / or sucralose, and the acidulant includes citric acid and / or DL-malic acid.

[0026] As a preferred embodiment, the collagen peptide composition includes 450 parts of collagen peptide A, 10 parts of elastin peptide, 30 parts of collagen peptide B, 5 parts of ray collagen peptide, 5 parts of fish oligopeptide, 30 parts of xylitol, 1.5 parts of sodium hyaluronate, 0.3 parts of pectin, 0.3 parts of konjac gum, 0.02 parts of zinc gluconate, 0.1 parts of vitamin C, 0.1 parts of vitamin E, 0.01 parts of sweetener, and 0.015 parts of acidulant.

[0027] Furthermore, the present invention also provides a method for preparing the above-mentioned collagen peptide composition, comprising the following steps: uniformly mixing collagen peptide A, xylitol, elastin peptide, collagen peptide B, skate collagen peptide, fish oligopeptide, sodium hyaluronate, pectin, konjac gum, zinc gluconate, vitamin C, vitamin E, sweetener, and acidulant to obtain the composition.

[0028] Furthermore, the collagen peptide composition provided by the present invention or the collagen peptide combination prepared by the above preparation method can be used to prepare moisturizing, anti-sugar and antioxidant products.

[0029] Furthermore, the product also includes edible additives.

[0030] Furthermore, the dosage form of the product includes tablets, powders or pills.

[0031] The technical effects achieved by the present invention are:

[0032] (1) The composition of the present invention is based on a mixture of collagen peptide A, elastin peptide, collagen peptide B, skate collagen peptide and fish oligopeptide. The combination of multiple collagen peptides can better improve the skin moisturizing effect and increase the collagen content, so that the composition can better improve skin elasticity and improve the skin's water retention effect.

[0033] (2) The present invention also adds sodium hyaluronate, pectin and konjac gum. Sodium hyaluronate has the effect of moisturizing and repairing the skin, and can increase the elasticity and softness of the skin; pectin contains a variety of polysaccharides with strong antioxidant capacity, which can neutralize free radicals, reduce oxidative damage, and have a certain effect on delaying aging; konjac gum is rich in collagen, starch, etc., and after penetrating into the body, it can effectively increase the sense of fullness. In addition, it can promote the discharge of intestinal waste, accelerate intestinal peristalsis, and improve constipation. During the implementation process, it was unexpectedly found that by controlling the mass ratio of sodium hyaluronate, pectin and konjac gum, the stability of collagen peptide can be significantly improved, and the collagen peptide can be better absorbed, so that the composition can have better moisturizing, anti-sugar and antioxidant effects.

[0034] (3) The present invention also adds auxiliary nutrients such as zinc gluconate, vitamin C, vitamin E, etc. to the composition and processes the collagen with small molecules, so that the effective ingredients can be better utilized and absorbed, and finally develops a collagen drink with high content, good taste and good stability. DETAILED DESCRIPTION

[0035] The following describes the embodiments of the present invention through specific examples, and those skilled in the art can easily understand other advantages and effects of the present invention from the contents disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments, and the details in this specification can also be modified or changed in various ways based on different viewpoints and applications without departing from the spirit of the present invention.

[0036] Before further describing the specific embodiments of the present invention, it should be understood that the scope of protection of the present invention is not limited to the specific embodiments described below; it should also be understood that the terms used in the examples of the present invention are for describing specific embodiments rather than for limiting the scope of protection of the present invention.

[0037] When the embodiment gives a numerical range, it should be understood that, unless otherwise specified in the present invention, the two endpoints of each numerical range and any numerical value between the two endpoints can be selected. Unless otherwise defined, all technical and scientific terms used herein have the same meanings as those of ordinary skill in the art to which the present invention belongs.

[0038] The following sources of raw materials are provided for illustrative purposes:

[0039] Collagen peptide A: average molecular weight less than 1000Da. Purchased from Hubei Ruibang Biotechnology Co., Ltd.; collagen peptide B: average molecular weight less than 500Da, CTP content higher than 30%, purchased from Shanghai Zhaoming Industrial Co., Ltd.; elastin peptide: purchased from Shanghai Ruixinda Health Technology Co., Ltd.; skate collagen peptide: purchased from Shanghai Kaida Biotechnology Co., Ltd.; fish oligopeptide: purchased from Beijing Shengminuo Biotechnology Co., Ltd.; sodium hyaluronate: model 80,200-200,000, purchased from Shandong Focus Freda Biological Co., Ltd.; pectin: purchased from Yantai DSM Andre Pectin Co., Ltd.; konjac gum: purchased from Sanyuan Lihua Biotechnology Co., Ltd.; zinc gluconate: purchased from Zhengzhou Ruipu Bioengineering Co., Ltd.; xylitol: purchased from Zhejiang Huakang Pharmaceutical Co., Ltd.; the remaining raw materials are all common commercial products, so their sources are not specifically limited.

[0040] Example 1-5 A high concentration collagen peptide composition and its preparation method

[0041] The specific collagen compositions of Examples 1 to 5 are shown in Table 1 below:

[0042] Table 1

[0043]

[0044] The preparation method specifically comprises the following steps: uniformly mixing collagen peptide A, xylitol, elastin peptide, collagen peptide B, skate collagen peptide, fish oligopeptide, sodium hyaluronate, pectin, konjac gum, zinc gluconate, vitamin C, vitamin E, sweetener and acidulant to obtain the product.

[0045] Comparative Example 1

[0046] The only difference from Example 5 is that collagen peptide B is not added, the content of collagen peptide A is 480 parts, and the contents of other components remain unchanged.

[0047] The specific preparation method is: evenly mix collagen peptide A, xylitol, elastin peptide, skate collagen peptide, fish oligopeptide, sodium hyaluronate, pectin, konjac gum, zinc gluconate, vitamin C, vitamin E, sweetener and acidulant to obtain the product.

[0048] Comparative Example 2

[0049] The only difference from Example 5 is that the skate collagen peptide and fish oligopeptide are not added, the elastin content is 20 parts, and the contents of other components remain unchanged.

[0050] The specific preparation method is: evenly mix collagen peptide A, xylitol, elastin peptide, collagen peptide B, sodium hyaluronate, pectin, konjac gum, zinc gluconate, vitamin C, vitamin E, sweetener and acidulant to obtain the product.

[0051] Comparative Example 3

[0052] The only difference from Example 5 is that pectin and konjac gum are replaced by sodium hyaluronate, namely 1.8 parts of sodium hyaluronate, and the contents of other components remain unchanged.

[0053] The specific preparation method is: evenly mix collagen peptide A, xylitol, elastin peptide, collagen peptide B, skate collagen peptide, fish oligopeptide, sodium hyaluronate, zinc gluconate, vitamin C, vitamin E, sweetener and acidulant.

[0054] Comparative Example 4

[0055] The only difference from Example 5 is that the mass ratio of sodium hyaluronate, pectin and konjac gum is 22:1:1, and the contents of other components remain unchanged. That is:

[0056] Sodium hyaluronate (part) 1.65 Pectin (parts) 0.075 Konjac gum (part) 0.075

[0057] The specific preparation method is: evenly mix collagen peptide A, xylitol, elastin peptide, collagen peptide B, skate collagen peptide, fish oligopeptide, sodium hyaluronate, pectin, konjac gum, zinc gluconate, vitamin C, vitamin E, sweetener and acidulant to obtain the product.

[0058] Comparative Example 5

[0059] The only difference from Example 5 is that the mass ratio of sodium hyaluronate, pectin and konjac gum is 3:1:1, and the contents of other components remain unchanged. That is:

[0060] Sodium hyaluronate (part) 1.08 Pectin (parts) 0.36 Konjac gum (part) 0.36

[0061] The specific preparation method is: evenly mix collagen peptide A, xylitol, elastin peptide, collagen peptide B, skate collagen peptide, fish oligopeptide, sodium hyaluronate, pectin, konjac gum, zinc gluconate, vitamin C, vitamin E, sweetener and acidulant to obtain the product.

[0062] 1. DPPH free radical scavenging rate test

[0063] 1.1 Test substances: the collagen peptide compositions in Examples 1-5 and Comparative Examples 1-5.

[0064] 1.2 Experimental methods:

[0065] Take 2 mL of the collagen peptide composition in each example and add it to a test tube, then add 2 mL of 0.1 mmol / L DPPH solution (prepared with 95% ethanol solution by volume) to the test tube, mix well and place in the dark for 30 minutes, measure the absorbance at a wavelength of 517 nm, perform three parallel samples for each group, and take the average value.

[0066] Among them, DPPH free radical scavenging rate = ×100%;

[0067] In the above formula, A0 is the absorbance of DPPH solution after adding the test substance, and A is the absorbance of DPPH solution when no test substance is added.

[0068] 1.3 Experimental results:

[0069] The experimental results are shown in Table 2 below:

[0070] Table 2

[0071]

[0072] According to the test data in Table 2 above, the compositions prepared in Examples 1-5 of the present invention have a good effect of scavenging DPPH free radicals, especially the composition prepared in Example 5 has the best effect of scavenging DPPH free radicals, reaching more than 83%; in Comparative Examples 1-2, changing the type of collagen peptide will significantly affect the effect of the composition in scavenging DPPH free radicals, and changing the type or mass ratio of sodium hyaluronate, pectin and konjac gum in Comparative Examples 3-5 will affect the effect of the composition in scavenging DPPH free radicals.

[0073] 2. Elastase Activity Inhibition Experiment

[0074] Experimental principle: Elastase is a highly selective and specific proteolytic enzyme. It catalyzes the hydrolysis of many amino acids such as glycine, leucine, alanine and other hydroxyl-containing polypeptide bonds, and can decompose elastin in connective tissue protein. Inhibiting the activity of elastase can effectively slow down the degradation of elastin and reduce the occurrence of skin aging, wrinkles and photoaging.

[0075] Determination of elastase inhibition rate: 90 μL buffer, 30 μL sample diluent of different concentrations and 10 μL substrate were added to a 96-well plate, mixed and incubated at 25 °C for 20 min. Subsequently, 20 μL elastase solution was added and incubated for 10 min, the absorbance was detected, and the average value was taken. The test results are shown in Table 3 below.

[0076] The elastase inhibition rate of the sample was calculated according to the following formula:

[0077] Elastase inhibition rate (%) = (control group - experimental group) / control group × 100%

[0078] Table 3

[0079]

[0080] According to the test data in Table 3 above, it can be seen that the compositions prepared in Examples 1-5 of the present invention have better effects on inhibiting elastase, especially the composition prepared in Example 5 has the best effect on inhibiting elastase; in Comparative Examples 1-2, changing the type of collagen peptide will significantly affect the effect of the composition on inhibiting elastase, and changing the type or mass ratio of sodium hyaluronate, pectin and konjac gum in Comparative Examples 3-5 will affect the effect of the composition on inhibiting elastase.

[0081] 3. Human Food Tasting Test

[0082] Test samples: compositions provided in Examples 1-5 and Comparative Examples 1-5;

[0083] Test method: A questionnaire was distributed to select people with skin problems. The subjects were randomly divided into groups and took 1 sample (5g of the composition) 1 hour before going to bed every day for 30 consecutive days. During the test, the subjects were not allowed to take items that maintain skin moisture and skin elasticity, or cosmetics that affect the results, and did not change their original eating habits during the test.

[0084] On the 0th day and the 30th day, the skin moisture content was tested with the skin moisture tester Corneometer CM825 to evaluate the skin moisture content before and after drinking. The probe repeated the measurement 3 times in the same tested area and took the average value.

[0085] Moisture content growth rate (%) = [(moisture content on the 30th day - moisture content on the 0th day) / moisture content on the 0th day] × 100%.

[0086] The skin condition on the 0th day and the 30th day was tested using a skin elasticity meter, Cutometer MPA580. The test site was the zygomatic area. The probe was used to measure the same test area three times and the average value was taken.

[0087] The test parameter is R2 (the ratio of the skin's rebound value Ua when there is no negative pressure to the maximum stretching value Uf when there is negative pressure). The closer R2 is to 1, the better the skin's elasticity. The average change value of R2 = R2 value on the 30th day - R2 value on the 0th day. The average change rate of R2 (%) = [average change value of R2 / R2 value on the 0th day] × 100%.

[0088] The test results are shown in Table 4 below.

[0089] Table 4

[0090]

[0091] According to the test data in Table 4, after taking the composition prepared by Examples 1-5 of the present invention before going to bed every day for 30 days, the skin moisture content growth rate reaches more than 10%, and the average R2 change rate reaches more than 12%. This shows that the composition prepared by the present invention can increase skin moisture, firmness and elasticity, and can reduce skin fine lines; the effect of the composition prepared by Comparative Examples 1-5 after taking is not as good as that of the composition prepared by Examples 1-5.

[0092] Finally, it should be noted that the above content is only used to illustrate the technical solution of the present invention, rather than to limit the scope of protection of the present invention. Simple modifications or equivalent substitutions of the technical solution of the present invention by ordinary technicians in this field do not deviate from the essence and scope of the technical solution of the present invention.

Claims

1. A high-concentration multi-collagen peptide composition, characterized in that: The invention comprises the following components by weight: 400-480 parts of collagen peptide A, 4-20 parts of elastin peptide, 20-40 parts of collagen peptide B, 2-10 parts of skate collagen peptide, 2-10 parts of fish oligopeptide, 20-40 parts of xylitol, 0.5-2 parts of sodium hyaluronate, 0.1-0.2 parts of pectin, 0.1-0.2 parts of konjac gum, 0.01-0.02 parts of zinc gluconate, 0.05-0.1 parts of vitamin C, 0.05-0.1 parts of vitamin E, 0.005-0.01 parts of steviol glycoside and / or sucralose and 0.01-0.02 parts of acidulant; The mass ratio of the collagen peptide A, elastin peptide, collagen peptide B, ray collagen peptide and fish oligopeptide is 40-48:0.4-2:2-4:0.2-1:0.2-1; The collagen peptide A has an average molecular weight of less than 1000 Da and was purchased from Hubei Ruibang Biotechnology Co., Ltd. The collagen peptide B has an average molecular weight of less than 500 Da and a CTP content of more than 30%, and is purchased from Shanghai Zhaoming Industrial Co., Ltd. The mass ratio of the sodium hyaluronate, pectin and konjac gum is 5-15:1:

1.

2. The high-concentration multi-collagen peptide composition according to claim 1, characterized in that: The mass ratio of the collagen peptide A, elastin peptide, collagen peptide B, ray collagen peptide and fish oligopeptide is 45:1:3:0.5:0.

5.

3. The high-concentration multi-collagen peptide composition according to claim 1, characterized in that: The invention is composed of the following components by weight: 420-460 parts of collagen peptide A, 8-15 parts of elastin peptide, 25-35 parts of collagen peptide B, 4-8 parts of skate collagen peptide, 4-8 parts of fish oligopeptide, 25-35 parts of xylitol, 1-2 parts of sodium hyaluronate, 0.15-0.2 parts of pectin, 0.15-0.2 parts of konjac gum, 0.01-0.02 parts of zinc gluconate, 0.05-0.1 parts of vitamin C, 0.05-0.1 parts of vitamin E, 0.005-0.01 parts of steviol glycoside and / or sucralose and 0.01-0.02 parts of acidulant.

4. The high-concentration multi-collagen peptide composition according to claim 1, characterized in that: The collagen peptide composition is composed of the following components in parts by weight: 450 parts of collagen peptide A, 10 parts of elastin peptide, 30 parts of collagen peptide B, 5 parts of skate collagen peptide, 5 parts of fish oligopeptide, 30 parts of xylitol, 1.5 parts of sodium hyaluronate, 0.15 parts of pectin, 0.15 parts of konjac gum, 0.02 parts of zinc gluconate, 0.1 parts of vitamin C, 0.1 parts of vitamin E, 0.01 parts of steviol glycoside and 0.015 parts of citric acid.

5. The method for preparing a high-concentration multi-collagen peptide composition according to claim 1, characterized in that: The following steps are involved: The collagen peptide A, xylitol, elastin peptide, collagen peptide B, skate collagen peptide, fish oligopeptide, sodium hyaluronate, pectin, konjac gum, zinc gluconate, vitamin C, vitamin E, steviol glycoside and / or sucralose, and acidulant are uniformly mixed to obtain the product.

6. Use of the high-concentration multiple collagen peptide composition according to any one of claims 1 to 4 or the high-concentration multiple collagen peptide composition prepared by the preparation method according to claim 5 in the preparation of moisturizing, anti-sugar and antioxidant products.

7. The use according to claim 6, characterized in that: The dosage forms of the product include tablets, powders or pills.

Citation Information

Patent Citations

  • Sodium hyaluronate collagen peptide solid beverage and preparation method thereof

    CN116268253A

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